IONS Ionis Pharmaceuticals, Inc. - Common Stock
$60,34
Preço · Ago 19, 2026
Fundamentais a partir de Jul 29, 2026
Intervalo 52 Semanas
$42–$87
41% of range
Classificação do Analista
BUY
31 analysts
Preço-Alvo
$89
+48% upside
P/E (TTM)
-25.4
ROE
-68.1%
Margem de Lucro Líquido
—
IONS Instantâneo da Ação Preço, capitalização de mercado, P/E, EPS, ROE, dívida/patrimônio, intervalo de 52 semanas
Preço
$60.34
Capitalização de Mercado
$9.85B
P/E (TTM)
-25.4
EPS (TTM)
$-2.38
Receita (TTM)
—
Rendimento div.
—
ROE
-68.1%
Dívida/Capital
3.6
Intervalo 52 Semanas
$42 – $87
IONS Gráfico de Preço da Ação OHLCV diário com indicadores técnicos — panorâmica, zoom e personalize sua visualização
Configure
Desempenho de 10 Anos Tendências de receita, lucro líquido, margens e EPS
Receita e Lucro Líquido
—
2016-12-31
→
2017-12-31
EPS
$-2.38
2016-12-31
→
2025-12-31
Fluxo de caixa livre
$-320M
2016-12-31
→
2025-12-31
Margens
—
Avaliação Rácios P/E, P/S, P/B, EV/EBITDA — a ação está cara ou barata?
Métrica
Tendência de 5 anos
IONS
Mediana de Pares
P/E (TTM)
-25.4
16.0
P/S (TTM)
10.4
32.5
P/B
20.1
3.9
EV / EBITDA
-23.4
—
Price / FCF (Preço / FCF)
-30.8
—
Lucratividade Margens bruta, operacional e líquida; ROE, ROA, ROIC
Métrica
Tendência de 5 anos
IONS
Mediana de Pares
ROA
-11.7%
-22.2%
ROE
-68.1%
-37.6%
ROIC
-17.1%
—
Saúde financeira Dívida, liquidez, solvência — força do balanço patrimonial
Métrica
Tendência de 5 anos
IONS
Mediana de Pares
Debt / Equity (Dívida / Patrimônio Líquido)
3.6
0.0
Current Ratio (Índice de liquidez corrente)
3.8
5.7
Quick Ratio (Índice de Liquidez Seca)
3.4
—
Crescimento Crescimento da receita, EPS e lucro líquido: YoY, CAGR 3 anos, CAGR 5 anos
Métrica
Tendência de 5 anos
IONS
Mediana de Pares
Eficiência de Capital Giro de ativos, giro de estoques, giro de contas a receber
Métrica
Tendência de 5 anos
IONS
Mediana de Pares
IONS Consenso dos analistas Opiniões de analistas otimistas e pessimistas, preço-alvo de 12 meses, potencial de alta
COMPRA
31 analistas
- Compra forte 8 25,8%
- Compra 17 54,8%
- Manter 6 19,4%
- Venda 0 0,0%
- Venda forte 0 0,0%
Preço-alvo de 12 meses
21 analistas · 2026-08-18
Mediana
$90.00
← Abaixo de todos os alvos
$60.34
Mín
$66.00
Máx
$115.00
Alvo mediano
$90.00
+49,2%
Alvo médio
$89.33
+48,1%
Histórico de Lucros EPS real vs. estimativa, surpresa %, taxa de acerto, próxima data de resultados
Surpresa Média
0.42%
| Período | EPS Actual | EPS est. | Surpresa |
|---|---|---|---|
| 30 de Junho de 2026 | $-0.69 | $-1.09 | 0.40% |
| 31 de Março de 2026 | $-0.56 | $-0.93 | 0.37% |
| 31 de Dezembro de 2025 | $-1.41 | $-1.35 | -0.06% |
| 30 de Setembro de 2025 | $-0.80 | $-1.26 | 0.46% |
| 30 de Junho de 2025 | $0.70 | $-0.44 | 1.1% |
| 31 de Março de 2025 | $-0.93 | $-1.14 | 0.21% |
Comparação de pares (subindústria GICS) Métricas chave vs pares do setor
| Ticker | Capitalização de Mercado | P/E | Receita YoY | Margem Líquida | ROE | Margem Bruta |
|---|---|---|---|---|---|---|
| IONS | $12.92B | -33.2 | — | — | -68.1% | — |
| SMMT | $13.56B | -12.1 | — | — | -235.1% | — |
| KYMR | $6.33B | -21.1 | -16.7% | -794.0% | -24.4% | — |
| APGE | $5.16B | -17.9 | — | — | — | — |
| PTGX | $5.47B | -42.6 | -89.4% | -282.8% | -20.3% | — |
| KRYS | $7.20B | 36.0 | 33.9% | 52.6% | 18.1% | — |
| SYRE | $2.56B | 10.1 | -62.0% | — | -26.5% | — |
| PCVX | $6.05B | -8.2 | — | — | -26.6% | — |
| IMVT | $5.07B | -9.0 | 229.2% | — | -73.7% | — |
| TWST | $1.71B | -21.6 | 20.3% | -20.6% | -17.0% | — |
| IBRX | $2.00B | -5.2 | 668.3% | -310.2% | 71.0% | — |
Fundamentos Completos Todas as métricas por ano — demonstração de resultados, balanço patrimonial, fluxo de caixa
Demonstração de Resultados 16
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | · | · | $508M | $347M | $284M | $214M | |
| Cost of Revenue | $16M | $11M | $9M | $14M | $11M | $12M | $4M | $2M | $0 | $0 | · | · | |
| R&D Expense | $916M | $902M | $900M | · | $638M | $531M | $462M | $412M | $372M | $340M | $320M | $239M | |
| SG&A Expense | $394M | $267M | $233M | $150M | $186M | $354M | $287M | $245M | $108M | $49M | $37M | $20M | |
| Operating Expenses | $1.33B | $1.18B | $1.14B | $998M | $841M | $901M | $757M | $661M | $483M | $393M | $359M | $262M | |
| Operating Income | $-382M | $-475M | $-354M | $-410M | $-30M | $-172M | $366M | $-61M | $31M | $-20M | $-76M | $-48M | |
| Interest Expense | $17M | $17M | $13M | $8M | $9M | $10M | $12M | $45M | $45M | $39M | $37M | $22M | |
| Other Non-op | $-15M | $1M | $14M | $-7M | $-10M | $-62.0K | $-686.0K | $-182.0K | $-4M | $0 | · | · | |
| Pretax Income | $-380M | $-460M | $-334M | $-258M | $-29M | $-135M | $339M | $-76M | $-17M | $-57M | $-88M | $-54M | |
| Income Tax | $2M | $-6M | $32M | $12M | $-551.0K | $345M | $52M | $-291M | $-6M | $3M | $372.0K | $-15M | |
| Net Income | $-381M | $-454M | $-366M | $-270M | $-29M | $-444M | $278M | $274M | $346.0K | $-60M | $-88M | $-39M | |
| EPS (Basic) | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 | $-3.18 | $2.00 | $2.09 | $0.15 | $-0.50 | $-0.74 | · | |
| EPS (Diluted) | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 | $-3.18 | $1.90 | $2.07 | $0.15 | $-0.50 | $-0.74 | · | |
| Shares (Basic) | 160,010,000 | 149,514,000 | 143,190,000 | 141,848,000 | 141,021,000 | 139,612,000 | 139,998,000 | 132,320,000 | 124,016,000 | 120,933,000 | 119,719,000 | · | |
| Shares (Diluted) | 160,010,000 | 149,514,000 | 143,190,000 | 141,848,000 | 141,021,000 | 139,612,000 | 153,164,000 | 134,056,000 | 126,098,000 | 120,933,000 | 119,719,000 | · | |
| EBITDA | $-382M | $-475M | $-354M | $-410M | $-30M | $-172M | $366M | $-61M | $25M | $-46M | $-76M | $-48M |
Balanço Patrimonial 24
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $372M | $242M | $399M | $276M | $869M | $398M | $683M | $279M | $130M | $85M | $129M | $143M | |
| Short-term Investments | $2.31B | $2.06B | $1.93B | $1.71B | $1.25B | · | · | · | · | · | · | · | |
| Inventory | $10M | $13M | $7M | $22M | $25M | $22M | $18M | $9M | $10M | · | · | · | |
| Other Current Assets | $237M | $218M | $205M | $168M | $143M | $140M | $140M | $102M | $73M | $17M | $15M | $16M | |
| Current Assets | $2.99B | $2.62B | $2.64B | $2.20B | $2.35B | $2.13B | $2.72B | $2.21B | $1.17B | $798M | $837M | $837M | |
| PP&E (Net) | $123M | $94M | $71M | $74M | $178M | $181M | $154M | $132M | $122M | $93M | $90M | $89M | |
| Accum. Depreciation | $109M | $106M | $97M | $88M | $103M | $87M | $74M | $61M | $88M | $80M | $73M | $66M | |
| Intangibles | · | · | · | · | $29M | $28M | $26M | $24M | $22M | $20M | · | · | |
| Other Non-current Assets | $172M | $127M | $105M | $75M | $71M | $50M | $28M | $13M | $10M | $1M | · | · | |
| Total Assets | $3.52B | $3.00B | $2.99B | $2.53B | $2.61B | $2.39B | $3.23B | $2.67B | $1.32B | $912M | $948M | $956M | |
| Accounts Payable | $28M | $43M | $26M | $18M | $12M | $17M | $16M | $29M | $25M | $21M | $28M | $18M | |
| Accrued Liabilities | $106M | $108M | $148M | $140M | $89M | $90M | $67M | $48M | $67M | $36M | $28M | $30M | |
| Current Liabilities | $782M | $309M | $448M | $312M | $241M | $599M | $273M | $280M | $244M | $134M | $149M | $115M | |
| Capital Leases | $262M | $162M | $171M | $179M | $19M | · | · | · | · | · | · | · | |
| Other Non-current Liabilities | $28M | $52M | $42M | $16M | $7M | · | · | · | · | · | · | · | |
| Total Liabilities | $3.03B | $2.42B | $2.60B | $1.96B | $1.84B | $1.65B | $1.55B | $1.48B | $957M | $813M | $747M | $698M | |
| Long-term Debt | $1.81B | $1.25B | $1.31B | $1.19B | · | · | · | · | · | · | · | · | |
| Total Debt | $1.76B | $1.20B | $1.24B | $1.18B | · | · | · | · | · | · | · | · | |
| Common Stock | $163.0K | $158.0K | $144.0K | $142.0K | $141.0K | $140.0K | $140.0K | $138.0K | $125.0K | $122.0K | $120.0K | $118.0K | |
| Retained Earnings | $-2.63B | $-2.25B | $-1.80B | $-1.43B | $-1.16B | $-1.13B | $-708M | $-967M | $-1.24B | $-1.18B | $-1.09B | $-1.01B | |
| AOCI | $-25M | $-31M | $-33M | $-57M | $-33M | $-21M | $-25M | $-32M | $-32M | $-30M | $-14M | $40M | |
| Stockholders' Equity | $489M | $588M | $387M | $573M | $772M | $743M | $1.47B | $1.05B | $281M | $100M | $201M | $258M | |
| Liabilities + Equity | $3.52B | $3.00B | $2.99B | $2.53B | $2.61B | $2.39B | $3.23B | $2.67B | $1.32B | $912M | $948M | $956M | |
| Shares Outstanding | 163,304,875 | 157,908,815 | 144,340,526 | 142,057,736 | 141,210,015 | 140,365,594 | 140,339,615 | 137,928,828 | 124,976,373 | 121,636,273 | 120,351,480 | 118,442,726 |
Fluxo de Caixa 14
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $134M | $130M | $106M | $100M | $121M | $230M | $147M | $131M | $86M | $72M | $59M | $31M | |
| Deferred Tax | $0 | $0 | $0 | $0 | $0 | $342M | $904.0K | $-291M | $0 | $0 | $0 | $-11M | |
| Amort. of Intangibles | $2M | $2M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | · | · | |
| Operating Cash Flow | $-269M | $-501M | $-308M | $-274M | $31M | $36M | $346M | $603M | $174M | $-112M | $21M | $6M | |
| CapEx | $51M | $45M | $24M | $16M | $12M | $35M | $31M | $14M | $35M | $7M | $8M | $8M | |
| Investing Cash Flow | $-278M | $-134M | $-214M | $-263M | $195M | $274M | $-41M | $-930M | $-358M | $57M | $-60M | · | |
| Stock Issued | $0 | $489M | $0 | $0 | · | $0 | $0 | $448M | $72M | $0 | $0 | $0 | |
| Stock Repurchased | · | · | · | $0 | $0 | $91M | $34M | $0 | $0 | · | · | · | |
| Net Stock Activity | $0 | $489M | · | $0 | $0 | $-91M | $-34M | · | $72M | · | $0 | $0 | |
| Financing Cash Flow | $676M | $478M | $644M | $-55M | $246M | $-597M | $100M | $476M | $229M | $11M | $25M | · | |
| Net Change in Cash | $130M | $-157M | $123M | $-593M | $472M | $-286M | $404M | $149M | $45M | $-44M | $-14M | · | |
| Taxes Paid | $-639.0K | $-6M | $48M | $5M | · | $26M | $9M | $0 | $0 | · | · | · | |
| Free Cash Flow | $-320M | $-546M | $-331M | $-290M | $19M | $772.0K | $315M | $589M | $139M | $-119M | $13M | $-1M | |
| Levered FCF | $-337M | $-563M | $-345M | $-299M | $10M | $-128M | $272M | $716M | $106M | $-159M | $-23M | $-17M |
Lucratividade 7
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | 4.8% | -13.4% | -26.7% | -22.3% | |
| Net Margin | · | · | · | · | · | · | · | · | -1.2% | -25.0% | -31.1% | -18.2% | |
| Pretax Margin | · | · | · | · | · | · | · | · | -4.6% | -24.1% | -31.0% | -25.4% | |
| EBITDA Margin | · | · | · | · | · | · | · | · | 4.8% | -13.4% | -26.7% | -22.3% | |
| ROA | -11.7% | -15.2% | -13.3% | -10.5% | -1.1% | -16.1% | 10.0% | 13.7% | -0.53% | -9.3% | -9.2% | -4.3% | |
| ROE | -68.1% | -71.9% | -104.3% | -40.1% | -3.8% | -39.0% | 23.4% | 41.2% | -2.8% | -57.6% | -38.5% | -12.3% | |
| ROIC | -17.1% | -26.0% | -23.8% | -24.5% | -3.8% | -58.4% | 21.8% | 16.5% | 5.5% | -48.1% | -37.9% | -13.3% |
Liquidez e Solvência 5
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.8 | 8.5 | 5.9 | 7.1 | 9.7 | 3.7 | 10.0 | 7.9 | 5.2 | 6.0 | 5.6 | 7.3 | |
| Quick Ratio | 3.4 | 7.4 | 5.2 | 6.4 | 3.6 | 0.7 | 2.5 | 1.0 | 0.6 | 0.6 | 0.9 | 1.2 | |
| Debt / Equity | 3.6 | 2.0 | 3.2 | 2.1 | · | · | · | · | · | · | · | · | |
| LT Debt / Equity | 2.7 | 2.0 | 3.2 | 2.1 | · | · | · | · | · | · | · | · | |
| Interest Coverage | -22.1 | -28.0 | -27.9 | -50.5 | -3.2 | -3.8 | 7.5 | -1.4 | 0.5 | -1.2 | -2.1 | -2.1 |
Eficiência 2
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | · | · | 0.5 | 0.4 | 0.3 | 0.2 | |
| Inventory Turnover | 1.4 | 1.1 | 0.4 | 0.6 | 0.5 | 0.6 | 0.3 | 0.2 | · | · | · | · |
Avaliação (TTM) 14
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $944M | $705M | $788M | $587M | $810M | $729M | $1.12B | $600M | $508M | $347M | $284M | $214M | |
| Net Income TTM | $-381M | $-454M | $-366M | $-270M | $-29M | $-444M | $278M | $274M | $346.0K | $-60M | $-88M | $-39M | |
| Market Cap | $12.92B | $5.52B | $7.30B | $5.37B | $4.30B | $7.94B | $8.48B | $7.46B | $6.29B | $5.82B | $7.45B | $7.31B | |
| Enterprise Value | $12.00B | $4.43B | $6.21B | $4.55B | · | · | · | · | · | · | · | · | |
| P/E | -33.2 | -11.5 | -19.8 | -19.9 | -152.2 | -17.8 | 31.8 | 26.1 | 335.3 | -95.7 | -83.7 | -176.4 | |
| P/S | 13.7 | 7.8 | 9.3 | 9.1 | 5.3 | 10.9 | 7.6 | 12.4 | 12.4 | 16.8 | 26.3 | 34.1 | |
| P/B | 26.4 | 9.2 | 18.9 | 9.4 | 5.6 | 9.4 | 5.8 | 7.1 | 19.0 | 58.4 | 37.1 | 28.4 | |
| P / Tangible Book | 26.4 | 9.4 | 18.9 | 9.4 | 5.8 | 11.1 | · | · | · | · | · | · | |
| P / Cash Flow | -48.1 | -11.0 | -23.7 | -19.6 | 139.5 | 221.1 | 24.5 | 12.4 | 36.1 | -51.9 | 352.8 | 1163.5 | |
| P / FCF | -40.4 | -10.1 | -22.0 | -18.5 | 228.0 | 10280.1 | 26.9 | 12.7 | 45.1 | -48.8 | 554.9 | -5930.8 | |
| EV / EBITDA | -31.4 | -9.3 | -17.6 | -11.1 | · | · | · | · | · | · | · | · | |
| EV / FCF | -37.5 | -8.1 | -18.7 | -15.7 | · | · | · | · | · | · | · | · | |
| EV / Revenue | 12.7 | 6.3 | 7.9 | 7.8 | · | · | · | · | · | · | · | · | |
| Earnings Yield | -3.0% | -8.7% | -5.1% | -5.0% | -0.66% | -5.6% | 3.1% | 3.8% | 0.30% | -1.1% | -1.2% | -0.57% |
Demonstração de Resultados 15
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $268M | $246M | $203M | $157M | $452M | $132M | $227M | $134M | $225M | $119M | $325M | $144M | $188M | $131M | $152M | $160M | |
| Cost of Revenue | $3M | $3M | $8M | $2M | $4M | $1M | $4M | $1M | $4M | $2M | $3M | $2M | $3M | $1M | $4M | $2M | |
| SG&A Expense | $150M | $150M | $130M | $97M | $91M | $76M | $88M | $62M | $65M | $53M | $71M | $70M | $46M | $46M | $48M | $34M | |
| Operating Expenses | $370M | $364M | $418M | $317M | $312M | $278M | $337M | $282M | $291M | $269M | $331M | $287M | $279M | $245M | $360M | $219M | |
| Operating Income | $-102M | $-117M | $-214M | $-160M | $140M | $-147M | $-111M | $-149M | $-66M | $-150M | $-6M | $-143M | $-90M | $-114M | $-208M | $-59M | |
| Interest Expense | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $4M | $2M | $2M | $2M | $2M | |
| Other Non-op | $987.0K | $-456.0K | $-16M | $363.0K | $102.0K | $465.0K | $302.0K | $142.0K | $610.0K | $277.0K | $235.0K | $2M | $11M | $230.0K | $123.0K | $5M | |
| Pretax Income | $-113M | $-92M | $-228M | $-128M | $124M | $-147M | $-107M | $-144M | $-66M | $-143M | $-3M | $-141M | $-77M | $-113M | $-44M | $-47M | |
| Income Tax | $1M | $218.0K | $1M | $213.0K | $-20.0K | $116.0K | $-3M | $-4M | $64.0K | $75.0K | $6M | $7M | $8M | $11M | $8M | $283.0K | |
| Net Income | $-115M | $-93M | $-229M | $-129M | $124M | $-147M | $-104M | $-140M | $-66M | $-143M | $-9M | $-147M | $-85M | $-124M | $-52M | $-47M | |
| EPS (Basic) | $-0.69 | $-0.56 | $-1.41 | $-0.80 | $0.78 | $-0.93 | $-0.66 | $-0.95 | $-0.45 | $-0.98 | $-0.06 | $-1.03 | $-0.60 | $-0.87 | $-0.37 | $-0.33 | |
| EPS (Diluted) | $-0.69 | $-0.56 | $-1.41 | $-0.80 | $0.70 | $-0.93 | $-0.66 | $-0.95 | $-0.45 | $-0.98 | $-0.06 | $-1.03 | $-0.60 | $-0.87 | $-0.37 | $-0.33 | |
| Shares (Basic) | 165,419,000 | 164,874,000 | -317,627,000 | 159,765,000 | 159,137,000 | 158,735,000 | -290,575,000 | 148,593,000 | 145,958,000 | 145,538,000 | -285,960,000 | 143,317,000 | 143,098,000 | 142,735,000 | -283,495,000 | 141,950,000 | |
| Shares (Diluted) | 165,419,000 | 164,874,000 | -340,821,000 | 159,765,000 | 182,331,000 | 158,735,000 | -290,575,000 | 148,593,000 | 145,958,000 | 145,538,000 | -285,960,000 | 143,317,000 | 143,098,000 | 142,735,000 | -283,495,000 | 141,950,000 | |
| EBITDA | $-102M | $-117M | · | $-160M | $140M | $-147M | · | $-149M | $-66M | $-150M | · | $-143M | $-90M | $-114M | · | $-59M |
Balanço Patrimonial 23
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $350M | $173M | $372M | $338M | $297M | $264M | $242M | $335M | $294M | $349M | · | $352M | $425M | $309M | · | $315M | |
| Short-term Investments | $1.70B | $1.75B | $2.31B | $1.90B | $1.99B | $1.88B | $2.06B | $2.15B | $1.78B | $1.86B | · | $1.88B | $1.96B | $2.04B | · | $1.67B | |
| Inventory | $51M | $6M | $10M | $10M | $8M | $12M | $13M | $28M | $29M | $30M | · | $26M | $26M | $22M | · | $21M | |
| Other Current Assets | $327M | $306M | $237M | $244M | $226M | $223M | $218M | $184M | $195M | $174M | · | $181M | $178M | $160M | · | $143M | |
| Current Assets | $2.49B | $2.94B | $2.99B | $2.52B | $2.58B | $2.42B | $2.62B | $2.71B | $2.33B | $2.42B | · | $2.58B | $2.62B | $2.54B | · | $2.15B | |
| PP&E (Net) | $155M | $142M | $123M | $106M | $112M | $103M | $94M | $83M | $76M | $73M | · | $71M | $92M | $85M | · | $181M | |
| Accum. Depreciation | · | · | $109M | · | · | · | $106M | · | · | · | · | · | · | · | · | · | |
| Intangibles | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $30M | |
| Other Non-current Assets | $117M | $136M | $172M | $166M | $132M | $132M | $127M | $120M | $119M | $106M | · | $104M | $86M | $78M | · | $59M | |
| Total Assets | $2.99B | $3.45B | $3.52B | $3.03B | $2.99B | $2.81B | $3.00B | $3.08B | $2.69B | $2.76B | · | $2.93B | $2.97B | $2.89B | · | $2.42B | |
| Accounts Payable | $48M | $26M | $28M | $14M | $23M | $17M | $43M | $9M | $9M | $13M | · | $6M | $24M | $10M | · | $21M | |
| Accrued Liabilities | $116M | $127M | $106M | $99M | $99M | $103M | $108M | $124M | $114M | $106M | · | $119M | $105M | $113M | · | $128M | |
| Current Liabilities | $316M | $717M | $782M | $903M | $897M | $250M | $309M | $305M | $306M | $328M | · | $404M | $288M | $259M | · | $283M | |
| Capital Leases | $262M | $259M | $262M | $263M | $164M | $159M | $162M | $168M | $166M | $169M | · | $173M | $175M | $177M | · | · | |
| Other Non-current Liabilities | $28M | $28M | · | $29M | $59M | $56M | · | $42M | $42M | $42M | · | $49M | $16M | $7M | · | · | |
| Total Liabilities | $2.55B | $2.96B | $3.03B | $2.42B | $2.35B | $2.34B | $2.42B | $2.42B | $2.43B | $2.47B | · | $2.62B | $2.54B | $2.40B | · | $1.83B | |
| Long-term Debt | · | · | $1.81B | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Common Stock | $166.0K | $166.0K | $163.0K | $161.0K | $159.0K | $159.0K | $158.0K | $158.0K | $146.0K | $146.0K | · | $143.0K | $143.0K | $143.0K | · | $142.0K | |
| Retained Earnings | $-2.84B | $-2.72B | $-2.63B | $-2.40B | $-2.27B | $-2.40B | $-2.25B | $-2.15B | $-2.00B | $-1.94B | · | $-1.79B | $-1.64B | $-1.55B | · | $-1.38B | |
| AOCI | $-34M | $-31M | $-25M | $-26M | $-28M | $-29M | $-31M | $-24M | $-35M | $-35M | · | $-46M | $-51M | $-49M | · | $-63M | |
| Stockholders' Equity | $440M | $491M | $489M | $618M | $632M | $476M | $588M | $662M | $264M | $297M | $387M | $315M | $428M | $487M | $573M | $594M | |
| Liabilities + Equity | $2.99B | $3.45B | $3.52B | $3.03B | $2.99B | $2.81B | $3.00B | $3.08B | $2.69B | $2.76B | · | $2.93B | $2.97B | $2.89B | · | $2.42B | |
| Shares Outstanding | 165,636,792 | 165,902,064 | 163,304,875 | 161,137,930 | 159,196,782 | 159,041,259 | 157,908,815 | 157,813,136 | 146,025,246 | 145,844,719 | · | 143,393,493 | 143,167,414 | 143,022,539 | · | 142,017,411 |
Fluxo de Caixa 11
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $46M | $43M | $43M | $31M | $30M | $30M | $36M | $32M | $31M | $31M | $26M | $26M | $27M | $27M | $26M | $24M | |
| Amort. of Intangibles | $700.0K | $661.0K | $638.0K | $621.0K | $598.0K | $582.0K | $459.0K | $617.0K | $621.0K | $639.0K | $655.0K | $660.0K | $637.0K | $607.0K | $610.0K | $608.0K | |
| Operating Cash Flow | $566M | $-793M | $-138M | $-131M | $151M | $-151M | $-116M | $-115M | $-120M | $-150M | $33M | $-109M | $-97M | $-134M | $-200M | $-24M | |
| CapEx | $16M | $22M | $21M | $5M | $12M | $13M | $25M | $9M | $6M | $4M | $-819.0K | $2M | $12M | $10M | $4M | $6M | |
| Investing Cash Flow | $23M | $537M | $-420M | $91M | $-120M | $170M | $68M | $-341M | $62M | $76M | $-27M | $69M | $70M | $-326M | $212M | $-184M | |
| Stock Issued | · | · | $0 | · | · | · | $27.0K | · | · | · | $0 | · | · | · | · | · | |
| Financing Cash Flow | $-412M | $57M | $591M | $81M | $1M | $2M | $-44M | $496M | $3M | $24M | $41M | $-32M | $144M | $492M | $-51M | $2M | |
| Net Change in Cash | $177M | $-199M | $34M | $41M | $33M | $22M | $-93M | $41M | $-55M | $-50M | $47M | $-73M | $116M | $33M | $-39M | $-207M | |
| Taxes Paid | $1M | $-8.0K | $22.0K | $-278.0K | $17.0K | $-400.0K | $-8M | $80.0K | $2M | $13.0K | · | · | · | · | · | · | |
| Free Cash Flow | · | $-815M | · | · | · | $-163M | · | · | · | $-154M | · | · | · | $-144M | · | · | |
| Levered FCF | · | $-820M | · | · | · | $-167M | · | · | · | $-159M | · | · | · | $-146M | · | · |
Lucratividade 7
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -38.2% | -47.7% | · | -102.2% | 30.9% | -111.6% | · | -111.1% | -29.3% | -125.1% | · | -99.4% | -47.9% | -87.5% | · | -37.0% | |
| Net Margin | -42.8% | -37.6% | · | -82.1% | 27.3% | -111.6% | · | -105.0% | -29.4% | -119.5% | · | -102.2% | -45.3% | -95.2% | · | -29.4% | |
| Pretax Margin | -42.3% | -37.5% | · | -81.9% | 27.3% | -111.6% | · | -107.7% | -29.4% | -119.4% | · | -97.6% | -41.1% | -86.5% | · | -29.2% | |
| EBITDA Margin | -38.2% | -47.7% | · | -102.2% | 30.9% | -111.6% | · | -111.1% | -29.3% | -125.1% | · | -99.4% | -47.9% | -87.5% | · | -37.0% | |
| ROA | -3.8% | -2.9% | · | -4.2% | 4.3% | -5.3% | · | -4.7% | -2.3% | -5.1% | · | -5.5% | -3.1% | -4.6% | · | -1.9% | |
| ROE | -21.4% | -19.1% | · | -20.1% | 27.6% | -38.0% | · | -28.7% | -19.1% | -36.5% | · | -32.4% | -16.2% | -20.8% | · | -8.3% | |
| ROIC | -23.5% | -23.9% | · | -26.0% | 22.1% | -30.9% | · | -21.9% | -25.1% | -50.4% | · | -47.5% | -23.2% | -25.8% | · | -10.0% |
Liquidez e Solvência 3
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 7.9 | 4.1 | · | 2.8 | 2.9 | 9.7 | · | 8.9 | 7.6 | 7.4 | · | 6.4 | 9.1 | 9.8 | · | 7.6 | |
| Quick Ratio | 6.5 | 2.7 | · | 2.5 | 2.6 | 8.6 | · | 8.2 | 6.8 | 6.7 | · | 5.5 | 8.3 | 9.1 | · | 7.0 | |
| Interest Coverage | -22.2 | -22.8 | · | -38.0 | 34.0 | -35.7 | · | -35.7 | -14.7 | -36.0 | · | -34.1 | -39.4 | -71.0 | · | -27.7 |
Eficiência 2
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.1 | · | 0.1 | 0.2 | 0.0 | · | 0.0 | 0.1 | 0.0 | · | 0.1 | 0.1 | 0.0 | · | 0.1 | |
| Inventory Turnover | 0.1 | 0.3 | · | 0.1 | 0.2 | 0.1 | · | 0.0 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 |
Avaliação (TTM) 10
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $874M | $1.06B | · | $967M | $944M | $717M | · | $803M | $813M | $777M | · | $615M | $631M | $576M | · | $875M | |
| Net Income TTM | $-565M | $-327M | · | $-256M | $-268M | $-458M | · | $-359M | $-366M | $-385M | · | $-409M | $-309M | $-329M | · | $7M | |
| Market Cap | $13.13B | $12.46B | · | $10.54B | $6.29B | $4.80B | · | $6.32B | $6.96B | $6.32B | · | $6.50B | $5.87B | $5.11B | · | $6.28B | |
| P/E | -22.9 | -36.3 | · | -38.7 | -21.5 | -10.1 | · | -16.4 | -18.9 | -16.2 | · | -15.8 | -18.9 | -15.5 | · | -368.6 | |
| P/S | 15.0 | 11.8 | · | 10.9 | 6.7 | 6.7 | · | 7.9 | 8.6 | 8.1 | · | 10.6 | 9.3 | 8.9 | · | 7.2 | |
| P/B | 29.9 | 25.4 | · | 17.1 | 10.0 | 10.1 | · | 9.5 | 26.4 | 21.3 | · | 20.6 | 13.7 | 10.5 | · | 10.6 | |
| P / Tangible Book | 29.9 | 25.4 | · | 17.1 | 10.0 | 10.1 | · | 9.5 | 26.4 | 21.3 | · | 20.6 | 13.7 | 10.5 | · | 11.1 | |
| P / Cash Flow | · | -15.7 | · | · | · | -31.8 | · | · | · | -42.2 | · | · | · | -38.1 | · | · | |
| P / FCF | · | -15.3 | · | · | · | -29.4 | · | · | · | -40.9 | · | · | · | -35.4 | · | · | |
| Earnings Yield | -4.4% | -2.8% | · | -2.6% | -4.7% | -9.9% | · | -6.1% | -5.3% | -6.2% | · | -6.3% | -5.3% | -6.5% | · | -0.27% |
Demonstrações Financeiras Demonstração de resultados, balanço patrimonial, fluxo de caixa — anual, últimos 5 anos
Demonstração de Resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Lucro líquido | $-381M | $-454M | $-366M | $-270M | $-29M |
| EPS Diluído | $-2.38 | $-3.04 | $-2.56 | $-1.90 | $-0.20 |
Balanço Patrimonial
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Dívida / Patrimônio Líquido | 3.6 | 2.0 | 3.2 | 2.1 | — |
| Índice de liquidez corrente | 3.8 | 8.5 | 5.9 | 7.1 | 9.7 |
| Índice de Liquidez Seca | 3.4 | 7.4 | 5.2 | 6.4 | 3.6 |
Fluxo de Caixa
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Fluxo de caixa livre | $-320M | $-546M | $-331M | $-290M | $19M |
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Investidores institucionais (13F) 575 declarantes · $10.8B total · Em 30 de Junho de 2026
Instituições que relatam a posse desta ação em seu Formulário 13F trimestral da SEC. Apenas posições compradas; um único declarante pode aparecer duas vezes para opções separadas. Grandes posições de compra/venda compensatórias geralmente refletem market-making ou inventário protegido, não convicção direcional.
Atividade institucional — Q2 2026 vs trimestre anterior
| Novas posições | Posições encerradas | Aumentou | Diminuído | Variação líquida de ações |
|---|---|---|---|---|
| 80 (-4 vs trimestre anterior) | 40 (-25 vs trimestre anterior) | 199 (+17 vs trimestre anterior) | 156 (+3 vs trimestre anterior) | +28.2M |
Comparado a Q1 2026. Os registros do Formulário 13F da SEC devem ser feitos em até 45 dias após o final do trimestre, mais um pequeno período de tolerância para registrantes atrasados — trimestres ainda dentro desse período são ignorados em favor do par mais recente totalmente reportado.
| Instituição | Valor | Ações | % de 13F rastreado | Tipo |
|---|---|---|---|---|
| Capital World Investors | $1.718.152.930 | 21.669.226 | 15,90% | Ações |
| FMR LLC | $1.062.239.646 | 13.396.893 | 9,83% | Ações |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $623.182.054 | 7.859.529 | 5,77% | Ações |
| VANGUARD CAPITAL MANAGEMENT LLC | $571.799.597 | 7.211.497 | 5,29% | Ações |
| WELLINGTON MANAGEMENT GROUP LLP | $558.240.214 | 7.040.487 | 5,17% | Ações |
| TWO SIGMA INVESTMENTS, LP | $495.748.197 | 6.252.342 | 4,59% | Ações |
| STATE STREET CORP | $343.710.098 | 4.334.848 | 3,18% | Ações |
| GEODE CAPITAL MANAGEMENT, LLC | $260.920.005 | 3.157.327 | 2,41% | Ações |
| TWO SIGMA ADVISERS, LP | $241.452.501 | 3.052.111 | 2,23% | Ações |
| Artisan Partners Limited Partnership | $209.327.536 | 2.640.024 | 1,94% | Ações |
| Tweedy, Browne Co LLC | $180.805.859 | 2.280.311 | 1,67% | Ações |
| Deep Track Capital, LP | $174.438.000 | 2.200.000 | 1,61% | Ações |
| BAKER BROS. ADVISORS LP | $162.364.274 | 2.047.727 | 1,50% | Ações |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $156.967.955 | 1.979.669 | 1,45% | Ações |
| AMERICAN CENTURY COMPANIES INC | $154.383.816 | 1.947.076 | 1,43% | Ações |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $127.260.529 | 1.605.001 | 1,18% | Ações |
| Pictet Asset Management Holding SA | $126.981.913 | 1.596.998 | 1,18% | Ações |
| BARCLAYS PLC | $125.150.305 | 1.578.387 | 1,16% | Ações |
| GOLDMAN SACHS GROUP INC | $117.215.755 | 1.478.317 | 1,08% | Ações |
| Polar Capital Holdings Plc | $115.289.325 | 1.454.021 | 1,07% | Ações |
| Alyeska Investment Group, L.P. | $112.426.560 | 1.417.916 | 1,04% | Ações |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $103.108.716 | 1.300.400 | 0,95% | Opção de compra |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $103.108.000 | 1.300.392 | 0,95% | Ações |
| VANGUARD FIDUCIARY TRUST CO | $84.114.400 | 1.060.845 | 0,78% | Ações |
| GROUPAMA ASSET MANAGMENT | $75.195.315 | 937.083 | 0,70% | Ações |
| Capital International Investors | $65.316.248 | 823.764 | 0,60% | Ações |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $65.184.309 | 822.100 | 0,60% | Opção de venda |
| Davern Capital Partners, LP | $63.329.637 | 798.709 | 0,59% | Ações |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | $62.422.083 | 787.263 | 0,58% | Ações |
| Connor, Clark & Lunn Investment Management Ltd. | $54.253.072 | 684.236 | 0,50% | Ações |
| Eversept Partners, LP | $52.702.794 | 664.684 | 0,49% | Ações |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $51.970.948 | 655.454 | 0,48% | Ações |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $51.370.722 | 647.884 | 0,48% | Ações |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $50.113.500 | 632.028 | 0,46% | Ações |
| Caption Management, LLC | $49.952.700 | 630.000 | 0,46% | Opção de compra |
| NEUBERGER BERMAN GROUP LLC | $46.951.653 | 592.151 | 0,43% | Ações |
| EVENTIDE ASSET MANAGEMENT, LLC | $45.591.750 | 575.000 | 0,42% | Ações |
| PERCEPTIVE ADVISORS LLC | $44.878.140 | 566.000 | 0,42% | Ações |
| RENAISSANCE TECHNOLOGIES LLC | $44.355.936 | 559.414 | 0,41% | Ações |
| JANE STREET GROUP, LLC | $44.045.595 | 555.500 | 0,41% | Opção de compra |
| JANE STREET GROUP, LLC | $43.070.328 | 543.200 | 0,40% | Opção de venda |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $41.414.514 | 522.317 | 0,38% | Ações |
| BOONE CAPITAL MANAGEMENT LLC | $41.228.976 | 519.977 | 0,38% | Ações |
| NEW YORK STATE COMMON RETIREMENT FUND | $39.648.965 | 500.050 | 0,37% | Ações |
| BNP PARIBAS FINANCIAL MARKETS | $36.049.119 | 454.649 | 0,33% | Ações |
| Candriam S.C.A. | $35.251.607 | 445.019 | 0,33% | Ações |
| FIRST TRUST ADVISORS LP | $33.872.360 | 427.197 | 0,31% | Ações |
| PINNACLE ASSOCIATES LTD | $33.282.136 | 419.752 | 0,31% | Ações |
| BANK OF AMERICA CORP /DE/ | $32.643.138 | 411.693 | 0,30% | Ações |
| NOMURA HOLDINGS INC | $31.889.804 | 402.192 | 0,30% | Ações |
| Ikarian Capital, LLC | $31.716.000 | 400.000 | 0,29% | Opção de compra |
| CITADEL ADVISORS LLC | $30.645.585 | 386.500 | 0,28% | Opção de venda |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $28.771.090 | 362.859 | 0,27% | Ações |
| BlackRock, Inc. | $28.184.582 | 355.462 | 0,26% | Ações |
| Caption Management, LLC | $27.426.411 | 345.900 | 0,25% | Opção de venda |
| TD Asset Management Inc | $27.002.051 | 340.548 | 0,25% | Ações |
| Freestone Grove Partners LP | $26.955.983 | 339.967 | 0,25% | Ações |
| AXA Investment Managers S.A. | $26.590.024 | 406.451 | 0,25% | Ações |
| Qube Research & Technologies Ltd | $26.479.054 | 333.952 | 0,25% | Ações |
| Capital Research Global Investors | $26.319.205 | 331.936 | 0,24% | Ações |
| CAPITAL FUND MANAGEMENT S.A. | $26.130.336 | 329.554 | 0,24% | Ações |
| ALLIANCEBERNSTEIN L.P. | $25.564.391 | 340.450 | 0,24% | Ações |
| Carmignac Gestion | $25.452.090 | 321.000 | 0,24% | Ações |
| Privium Fund Management B.V. | $25.366.774 | 319.924 | 0,23% | Ações |
| Swiss National Bank | $24.976.350 | 315.000 | 0,23% | Ações |
| ARK Investment Management LLC | $23.848.064 | 300.770 | 0,22% | Ações |
| Integral Health Asset Management, LLC | $23.787.000 | 300.000 | 0,22% | Opção de compra |
| Ikarian Capital, LLC | $23.787.000 | 300.000 | 0,22% | Opção de venda |
| MILLENNIUM MANAGEMENT LLC | $22.904.661 | 288.872 | 0,21% | Ações |
| DAVENPORT & Co LLC | $22.515.188 | 283.960 | 0,21% | Ações |
| Aberdeen Group plc | $21.995.046 | 277.400 | 0,20% | Ações |
| California Public Employees Retirement System | $21.475.141 | 270.843 | 0,20% | Ações |
| TimesSquare Capital Management, LLC | $20.700.361 | 275.674 | 0,19% | Ações |
| MILLENNIUM MANAGEMENT LLC | $20.417.175 | 257.500 | 0,19% | Opção de compra |
| TOCQUEVILLE ASSET MANAGEMENT L.P. | $19.918.837 | 251.215 | 0,18% | Ações |
| CITADEL ADVISORS LLC | $18.709.189 | 235.959 | 0,17% | Ações |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $18.514.136 | 233.499 | 0,17% | Ações |
| CITADEL ADVISORS LLC | $18.434.925 | 232.500 | 0,17% | Opção de compra |
| Orion Investment Co | $17.470.362 | 220.335 | 0,16% | Ações |
| Life Cycle Investment Partners Ltd | $17.435.554 | 219.896 | 0,16% | Ações |
| ALGERT GLOBAL LLC | $16.401.374 | 206.853 | 0,15% | Ações |
| Corient Private Wealth LP | $15.603.561 | 196.791 | 0,14% | Ações |
| Eagle Health Investments LP | $15.428.010 | 194.577 | 0,14% | Ações |
| SECTOR GAMMA AS | $15.022.918 | 189.468 | 0,14% | Ações |
| Polymer Capital Management (HK) LTD | $14.105.453 | 177.897 | 0,13% | Ações |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $13.252.259 | 176.485 | 0,12% | Ações |
| ADAR1 Capital Management, LLC | $13.184.817 | 166.286 | 0,12% | Ações |
| RHUMBLINE ADVISERS | $13.075.750 | 164.911 | 0,12% | Ações |
| Sicart Associates LLC | $12.741.427 | 160.694 | 0,12% | Ações |
| VANGUARD ASSET MANAGEMENT, Ltd | $12.296.928 | 155.088 | 0,11% | Ações |
| CSS LLC/IL | $12.074.995 | 152.289 | 0,11% | Ações |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | $11.996.656 | 151.301 | 0,11% | Ações |
| CITIGROUP INC | $11.996.577 | 151.300 | 0,11% | Opção de compra |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $11.893.500 | 150.000 | 0,11% | Ações |
| Focus Partners Wealth | $11.728.366 | 147.917 | 0,11% | Ações |
| Hudson Bay Capital Management LP | $11.497.050 | 145.000 | 0,11% | Ações |
| Artia Global Partners LP | $11.447.573 | 144.376 | 0,11% | Ações |
| Sonora Investment Management Group, LLC | $11.108.840 | 169.808 | 0,10% | Ações |
| Fisher Asset Management, LLC | $10.877.317 | 137.184 | 0,10% | Ações |
| Atle Fund Management AB | $10.873.116 | 137.131 | 0,10% | Ações |
Executivos da empresa 48 insiders · 30 diretores · 19 conselheiros
| Investidor com informação privilegiada | Função | Última atividade | Ações detidas | Compras 12m | Vendas 12m | Líquido 12m |
|---|---|---|---|---|---|---|
| Brett P Monia | Chief Executive Officer | 26 de Junho de 2026 M | 245.571 | 0 | 17 | $-42.648.430 |
| HOUGEN ELIZABETH L | EVP, Finance & CFO | 16 de Março de 2026 M | 82.660 | 0 | 6 | $-21.117.075 |
| Kleanthis G Xanthopoulos | President of Regulus | 3 de Dezembro de 2007 A | — | 0 | 0 | $0 |
| Holly B. Kordasiewicz | EVP, Chief Development Officer | 7 de Julho de 2026 S | 22.096 | 0 | 4 | $-4.810.107 |
| BENNETT C FRANK | EVP, Chief Scientific Officer | 7 de Julho de 2026 J | 0 | 0 | 14 | $-19.804.154 |
| Eugene Schneider | EVP, Chf Clinical Develop Ofcr | 26 de Junho de 2026 M | 77.114 | 0 | 6 | $-4.933.991 |
| Joseph Baroldi | EVP, Chief Business Officer | 26 de Junho de 2026 M | 4.669 | 0 | 17 | $-6.405.525 |
| O'NEIL PATRICK R. | EVP CLO & General Counsel | 26 de Junho de 2026 S | 61.470 | 0 | 16 | $-16.034.086 |
| Eric Swayze | EVP Research | 25 de Junho de 2026 S | 21.759 | 0 | 14 | $-8.058.784 |
| Brian Birchler | EVP, Corp and Development Ops | 15 de Abril de 2026 M | 67.500 | 0 | 6 | $-3.556.351 |
| Kyle Jenne | EVP, Chf GL Pdt Str Ofcr | 15 de Abril de 2026 M | 23.713 | 0 | 4 | $-3.334.240 |
| Shannon L. Devers | EVP, Chief Human Resources Ofc | 2 de Abril de 2026 S | 16.348 | 0 | 15 | $-8.854.430 |
| Richard S Geary | EVP, Chief Development Officer | 6 de Novembro de 2025 M | 59.657 | 0 | 13 | $-13.858.595 |
| Onaiza Cadoret-Manier | EVP,Chf GL Pdt Str & Oper Ofc | 2 de Fevereiro de 2024 S | 35.788 | 0 | 0 | $0 |
| Stanley T Crooke | Exec Chairman of the Board | 26 de Janeiro de 2021 S | 2.021 | 0 | 0 | $0 |
| Damien Mcdevitt | Chief Business Officer | 15 de Julho de 2019 M | 2.573 | 0 | 0 | $0 |
| Sarah Boyce | Chief Business Officer | 15 de Janeiro de 2018 M | 8.931 | 0 | 0 | $0 |
| ECKER DAVID J | Vice President | 2 de Setembro de 2008 M | 0 | 0 | 0 | $0 |
| Michael J Treble | Vice President, Pres of Ibis | 11 de Agosto de 2008 M | 0 | 0 | 0 | $0 |
| Jeffrey M Jonas | Executive Vice President | 2 de Janeiro de 2008 A | — | 0 | 0 | $0 |
| Mark K Wedel | VP & Chief Medical Officer | 6 de Julho de 2007 M | 6.603 | 0 | 0 | $0 |
| LEVIN ARTHUR A | Vice President | 25 de Abril de 2007 M | 1.674 | 0 | 0 | $0 |
| BROWN RICHARD K | Vice President | 8 de Março de 2006 M | 2.348 | 0 | 0 | $0 |
| MCNEIL JOHN A | Vice President | 3 de Janeiro de 2005 A | — | 0 | 0 | $0 |
| LOWENSTAM PATRICIA | Vice President | 3 de Janeiro de 2005 A | 603 | 0 | 0 | $0 |
| STEIN ARON | Vice President | 1 de Julho de 2004 J | 1.536 | 0 | 0 | $0 |
| Hans A De Haan | VP, Drug Development | 27 de Abril de 2004 S | 0 | 0 | 0 | $0 |
| LUNDSTEDT KAREN S | Vice President | 10 de Março de 2004 M | 5.407 | 0 | 0 | $0 |
| COLE DOUGLAS L | Vice President | 9 de Março de 2004 M | 9.616 | 0 | 0 | $0 |
| HOLMLUND JON T | Vice President | 1 de Julho de 2003 J | 983 | 0 | 0 | $0 |
| Michael R Hayden | Conselheiro | 31 de Julho de 2026 P | 24.000 | 2 | 0 | $1.058.700 |
| Peter N Reikes | Conselheiro | 15 de Julho de 2026 A | 14.222 | 0 | 0 | $0 |
| Ludwig Hantson | Conselheiro | 15 de Julho de 2026 A | — | 0 | 0 | $0 |
| Joan E Herman | Conselheiro | 15 de Julho de 2026 M | 51.306 | 0 | 2 | $-3.173.720 |
| BERTHELSEN SPENCER R | Conselheiro | 15 de Julho de 2026 M | 161.233 | 0 | 2 | $-1.193.280 |
| Allene M. Diaz | Conselheiro | 7 de Julho de 2026 M | 3.811 | 0 | 5 | $-5.278.717 |
| Michael J. Yang | Conselheiro | 1 de Julho de 2026 A | 7.940 | 0 | 0 | $0 |
| Joseph Loscalzo | Conselheiro | 1 de Julho de 2026 A | 36.330 | 0 | 6 | $-8.047.872 |
| Joseph Klein III | Conselheiro | 1 de Julho de 2026 A | 11.014 | 0 | 14 | $-9.356.036 |
| Lynne B Parshall | Conselheiro | 15 de Abril de 2026 S | 51.344 | 0 | 6 | $-2.171.964 |
| Joseph H Wender | Conselheiro | 1 de Dezembro de 2025 S | 36.035 | 0 | 13 | $-8.660.283 |
| MUTO FREDERICK T | Conselheiro | 15 de Julho de 2022 M | 59.597 | 0 | 0 | $0 |
| Breaux Castleman | Conselheiro | 1 de Julho de 2020 A | 19.183 | 0 | 0 | $0 |
| REED JOHN C | Conselheiro | 6 de Setembro de 2012 M | 0 | 0 | 0 | $0 |
| Richard D Dimarchi | Conselheiro | 1 de Julho de 2010 A | — | 0 | 0 | $0 |
| GARIELI CHRISTOPHER | Conselheiro | 1 de Julho de 2005 A | 155.431 | 0 | 0 | $0 |
| SKALETSKY MARK B | Conselheiro | 1 de Julho de 2004 A | — | 0 | 0 | $0 |
| ISIS PHARMACEUTICALS INC | Detentor de 10% | 10 de Outubro de 2020 P | 98.322.397 | 0 | 0 | $0 |
Executivos de declarações SEC Formulário 3/4/5; líquido = apenas P/V de mercado aberto
Ativistas e proprietários de 5%+ 5 participações
Investidores que apresentaram o Schedule 13D da SEC — propriedade benéfica acima de 5% com a intenção de influenciar o emissor (participações ativistas, campanhas no conselho, M&A). Cada linha mostra o estado mais recente conhecido da posição desse declarante.
| Declarante | Declarado | Participação | Status | Propósito | Declaração |
|---|---|---|---|---|---|
| Ionis Pharmaceuticals, Inc. (“Ionis”) ×8 declarações | 13 de Outubro de 2020 | — | Declaração inicial | M&A / venda | SEC |
| Isis Pharmaceuticals, Inc. (“ Isis ”) | 31 de Julho de 2015 | — | Declaração inicial | — | SEC |
| Isis Pharmaceuticals, Inc. (“Isis”), Stanley T. Crooke (“Crooke”), B. Lynne Parshall (“Parshall”) ×2 declarações | 6 de Novembro de 2014 | — | Declaração inicial | — | SEC |
| Genzyme Corporation | 15 de Janeiro de 2008 | — | Declaração inicial | Investimento passivo | SEC |
| Pessoa de relato não divulgada | 12 de Abril de 2001 | — | Declaração inicial | Investimento passivo | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Participação em ETFs Detido por 85 ETFs
O peso reflete apenas participações diretas em ações (N-PORT); fundos alavancados ou baseados em derivativos podem deter exposição adicional a swaps não mostrada.
| Fundo | Peso | Unidades | Em | Fonte |
|---|---|---|---|---|
| ARKG · ARK ETF Trust | 1,74% | 288.230 NS | 30 de Abril de 2026 | N-PORT |
| FXH · First Trust Exchange-Traded AlphaDE… | 1,72% | 201.598 NS | 30 de Abril de 2026 | N-PORT |
| BBP · ETFis Series Trust I | 1,48% | 11.708 NS | 30 de Abril de 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 1,37% | 3.614 NS | 31 de Maio de 2026 | N-PORT |
| CGMM · Capital Group Equity ETF Trust I | 1,14% | 414.653 NS | 31 de Maio de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,94% | 64.911 NS | 30 de Abril de 2026 | N-PORT |
| NUSC · Nushares ETF Trust | 0,87% | 150.398 NS | 30 de Abril de 2026 | N-PORT |
| TAX · EA Series Trust | 0,87% | 2.885 NS | 29 de Maio de 2026 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,84% | 1.257 NS | 30 de Abril de 2026 | N-PORT |
| COPY · RBB Fund Trust | 0,84% | 37.653 NS | 31 de Maio de 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,83% | 5.599 NS | 31 de Maio de 2026 | N-PORT |
| IBB · iShares Trust | 0,68% | 1.189.984 SH | 8 de Agosto de 2026 | Diário |
| FFND · Northern Lights Fund Trust II | 0,67% | 9.000 NS | 31 de Maio de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,64% | 8.994 SH | 8 de Agosto de 2026 | Diário |
| BIB · ProShares Trust | 0,63% | 6.109 NS | 31 de Maio de 2026 | N-PORT |
| MEDI · Harbor ETF Trust | 0,58% | 2.153 NS | 30 de Abril de 2026 | N-PORT |
| FDMO · FIDELITY COVINGTON TRUST | 0,53% | 60.169 NS | 30 de Abril de 2026 | N-PORT |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,53% | 36.525 NS | 30 de Abril de 2026 | N-PORT |
| OASC · Unified Series Trust | 0,47% | 5.182 NS | 31 de Maio de 2026 | N-PORT |
| QQQJ · Invesco Exchange-Traded Fund Trust … | 0,45% | 94.260 SH | 8 de Agosto de 2026 | Diário |
| CGGR · Capital Group Growth ETF | 0,36% | 1.150.284 NS | 31 de Maio de 2026 | N-PORT |
| VBK · VANGUARD INDEX FUNDS | 0,34% | 2.078.639 SH | 8 de Agosto de 2026 | Diário |
| SMMV · iShares Trust | 0,32% | 17.089 SH | 8 de Agosto de 2026 | Diário |
| BKMC · BNY Mellon ETF Trust | 0,30% | 25.160 NS | 30 de Abril de 2026 | N-PORT |
| ISCG · iShares Trust | 0,28% | 51.765 SH | 8 de Agosto de 2026 | Diário |
| SCHA · SCHWAB STRATEGIC TRUST | 0,26% | 778.644 NS | 31 de Maio de 2026 | N-PORT |
| IWP · iShares Trust | 0,24% | 895.755 SH | 8 de Agosto de 2026 | Diário |
| SCHM · SCHWAB STRATEGIC TRUST | 0,23% | 438.447 NS | 31 de Maio de 2026 | N-PORT |
| FSMD · FIDELITY COVINGTON TRUST | 0,23% | 71.810 NS | 30 de Abril de 2026 | N-PORT |
| BBMC · J.P. Morgan Exchange-Traded Fund Tr… | 0,22% | 60.227 NS | 30 de Abril de 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,22% | 110.695 SH | 8 de Agosto de 2026 | Diário |
| JMOM · J.P. Morgan Exchange-Traded Fund Tr… | 0,21% | 62.392 NS | 30 de Abril de 2026 | N-PORT |
| FFLG · FIDELITY COVINGTON TRUST | 0,21% | 16.403 NS | 30 de Abril de 2026 | N-PORT |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,20% | 36.263 NS | 30 de Abril de 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,20% | 50.927 SH | 8 de Agosto de 2026 | Diário |
| FHLC · FIDELITY COVINGTON TRUST | 0,19% | 70.978 NS | 30 de Abril de 2026 | N-PORT |
| VHT · VANGUARD WORLD FUND | 0,18% | 471.609 SH | 8 de Agosto de 2026 | Diário |
| SMLF · iShares Trust | 0,17% | 133.297 SH | 8 de Agosto de 2026 | Diário |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,16% | 10.044 NS | 30 de Abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,15% | 1.895.610 SH | 8 de Agosto de 2026 | Diário |
| VB · VANGUARD INDEX FUNDS | 0,15% | 3.600.281 SH | 8 de Agosto de 2026 | Diário |
| ESML · iShares Trust | 0,15% | 78.764 SH | 8 de Agosto de 2026 | Diário |
| IYH · iShares Trust | 0,15% | 98.412 SH | 8 de Agosto de 2026 | Diário |
| NBCR · Neuberger Berman ETF Trust | 0,14% | 16.581 NS | 31 de Maio de 2026 | N-PORT |
| ISCB · iShares Trust | 0,14% | 7.328 SH | 8 de Agosto de 2026 | Diário |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,13% | 176 NS | 31 de Maio de 2026 | N-PORT |
| SMMD · iShares Trust | 0,12% | 81.988 SH | 8 de Agosto de 2026 | Diário |
| WSML · iShares Trust | 0,08% | 9.548 SH | 8 de Agosto de 2026 | Diário |
| LRND · New York Life Investments ETF Trust | 0,07% | 2.788 NS | 30 de Abril de 2026 | N-PORT |
| EQAL · Invesco Exchange-Traded Fund Trust … | 0,07% | 9.928 SH | 8 de Agosto de 2026 | Diário |