TARA Protara Therapeutics, Inc. - Common Stock
$4,08
Preço · Ago 19, 2026
Fundamentais a partir de Ago 11, 2026
Intervalo 52 Semanas
$3–$8
23% of range
Classificação do Analista
BUY
14 analysts
Preço-Alvo
$27
+552% upside
P/E (TTM)
-3.0
ROE
-33.7%
Margem de Lucro Líquido
—
Sobre Protara Therapeutics, Inc. - Common Stock Visão geral da empresa da Wikipedia
Proteon Therapeutics, Inc. is a developer of pharmaceuticals with offices in Waltham, Massachusetts and Kansas City, Missouri.
Ler mais
Proteon Therapeutics, Inc. is a developer of pharmaceuticals with offices in Waltham, Massachusetts and Kansas City, Missouri.
Company History
Proteon was founded by Dr. F. Nicholas Franano based on technology created at Johns Hopkins University. Major investors in the company include MPM Capital, Rockhill Partners, TVM Capital, Skyline Ventures, Prism VentureWorks, Vectis Life Sciences and Intersouth Partners. They have invested over $72 million in the company.
The company is led by Timothy Noyes, CEO; Steven Burke, CMO; George Eldridge, CFO; and Scott Toner, director of marketing.
On March 5, 2009, the company announced that it had raised $32 million from its existing investors plus MPM Capital and Vectis Life Sciences. Proteon also announced that it had entered into an option agreement to be acquired by Novartis for up to $550 million. The company went public in 2014.
In September 2019, Proteon Therapeutics merged with ArTara Therapeutics.
PRT-201
Proteon is developing PRT-201 (vonapanitase), a drug to improve blood flow following vascular surgery procedures, and, more broadly, is interested in vascular access for hemodialysis and peripheral arterial disease (PAD). PRT-201 is a recombinant human elastase manufactured for Proteon by Lonza.
In September 2008, the company announced that the Food and Drug Administration had granted fast track status to PRT-201.
In December 2016, they announced that the phase III trial of PRT-201 hadn't reached its primary endpoint, causing Proteon's stock price to drop more than 75%.
Fonte: Wikipedia (Inglês), CC BY-SA 4.0 · Ver na Wikipedia ↗
TARA Instantâneo da Ação Preço, capitalização de mercado, P/E, EPS, ROE, dívida/patrimônio, intervalo de 52 semanas
Preço
$4.08
Capitalização de Mercado
$218M
P/E (TTM)
-3.0
EPS (TTM)
$-1.34
Receita (TTM)
—
Rendimento div.
—
ROE
-33.7%
Dívida/Capital
—
Intervalo 52 Semanas
$3 – $8
TARA Gráfico de Preço da Ação OHLCV diário com indicadores técnicos — panorâmica, zoom e personalize sua visualização
Configure
Desempenho de 10 Anos Tendências de receita, lucro líquido, margens e EPS
Receita e Lucro Líquido
—
EPS
$-1.34
2021-12-31
→
2025-12-31
Fluxo de caixa livre
$-56M
2016-12-31
→
2025-12-31
Margens
—
Avaliação Rácios P/E, P/S, P/B, EV/EBITDA — a ação está cara ou barata?
Métrica
Tendência de 5 anos
TARA
Mediana de Pares
P/E (TTM)
-3.0
88.5
P/B
1.1
3.6
Price / FCF (Preço / FCF)
-3.9
—
Lucratividade Margens bruta, operacional e líquida; ROE, ROA, ROIC
Métrica
Tendência de 5 anos
TARA
Mediana de Pares
ROA
-29.4%
-38.8%
ROE
-33.7%
-61.0%
Saúde financeira Dívida, liquidez, solvência — força do balanço patrimonial
Métrica
Tendência de 5 anos
TARA
Mediana de Pares
Current Ratio (Índice de liquidez corrente)
14.6
3.9
Quick Ratio (Índice de Liquidez Seca)
14.2
—
Crescimento Crescimento da receita, EPS e lucro líquido: YoY, CAGR 3 anos, CAGR 5 anos
Métrica
Tendência de 5 anos
TARA
Mediana de Pares
Eficiência de Capital Giro de ativos, giro de estoques, giro de contas a receber
Métrica
Tendência de 5 anos
TARA
Mediana de Pares
TARA Consenso dos analistas Opiniões de analistas otimistas e pessimistas, preço-alvo de 12 meses, potencial de alta
COMPRA
14 analistas
- Compra forte 3 21,4%
- Compra 10 71,4%
- Manter 1 7,1%
- Venda 0 0,0%
- Venda forte 0 0,0%
Preço-alvo de 12 meses
7 analistas · 2026-08-13
Mediana
$26.00
Média
$26.57
← Abaixo de todos os alvos
$4.08
Mín
$24.00
Máx
$30.00
Alvo mediano
$26.00
+538,0%
Alvo médio
$26.57
+552,1%
Histórico de Lucros EPS real vs. estimativa, surpresa %, taxa de acerto, próxima data de resultados
Surpresa Média
0.07%
| Período | EPS Actual | EPS est. | Surpresa |
|---|---|---|---|
| 31 de Março de 2026 | $-0.31 | $-0.38 | 0.07% |
| 31 de Dezembro de 2025 | $-0.37 | $-0.33 | -0.04% |
| 30 de Setembro de 2025 | $-0.31 | $-0.39 | 0.08% |
| 30 de Junho de 2025 | $-0.35 | $-0.41 | 0.06% |
| 31 de Março de 2025 | $-0.29 | $-0.46 | 0.17% |
Comparação de pares (subindústria GICS) Métricas chave vs pares do setor
| Ticker | Capitalização de Mercado | P/E | Receita YoY | Margem Líquida | ROE | Margem Bruta |
|---|---|---|---|---|---|---|
| TARA | $286M | -4.0 | — | — | -33.7% | — |
| CNXU | — | — | — | — | — | — |
| GLSI | $300M | -14.7 | — | — | -2159.7% | — |
| PYXS | $72M | -0.9 | -14.2% | -574.5% | -112.9% | — |
| RCEL | $105M | -2.0 | 11.5% | -67.8% | 328.9% | 82.1% |
| AKBA | $427M | -80.5 | 47.5% | -2.3% | -17.3% | — |
| ALEC | $172M | -1.1 | -79.1% | -679.2% | -280.7% | — |
| EBS | $644M | 13.3 | -28.8% | 7.1% | 9.9% | — |
| ARCT | $174M | -2.6 | -46.1% | -80.2% | -29.6% | — |
| NBP | — | — | — | — | — | — |
Fundamentos Completos Todas as métricas por ano — demonstração de resultados, balanço patrimonial, fluxo de caixa
Demonstração de Resultados 16
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | · | · | · | · | · | $3M | |
| R&D Expense | $43M | $32M | $25M | $17M | $21M | $12M | $4M | $12M | $22M | $19M | $12M | $6M | |
| SG&A Expense | $22M | $17M | $19M | $21M | $26M | $22M | $4M | $10M | $9M | $10M | $8M | $4M | |
| Operating Expenses | $65M | $49M | $44M | $67M | $47M | $34M | $8M | $21M | $30M | $29M | $21M | $11M | |
| Operating Income | $-65M | $-49M | $-44M | $-67M | $-47M | $-34M | $-8M | $-21M | $-30M | $-29M | $-21M | $-8M | |
| Interest Expense | · | · | · | · | $0 | $34.0K | · | · | · | · | · | $857.0K | |
| Interest Income | $6M | $4M | $3M | $1M | $237.0K | $500.0K | · | · | · | · | · | · | |
| Other Non-op | $7M | $5M | $3M | $1M | $237.0K | $466.0K | · | $207.0K | $139.0K | $-14.0K | $-651.0K | $5M | |
| Pretax Income | $57M | $45M | · | · | · | · | $-15M | $-21M | $-30M | $-29M | $-21M | $-3M | |
| Income Tax | · | · | · | · | · | · | · | · | · | · | · | $-110.0K | |
| Net Income | $-57M | $-45M | $-40M | $-66M | $-47M | $-34M | $-8M | $-21M | $-30M | $-29M | $-21M | $-3M | |
| EPS (Basic) | $-1.34 | $-2.17 | $-3.57 | $-5.86 | $-4.21 | · | · | · | · | · | · | · | |
| EPS (Diluted) | $-1.34 | $-2.17 | $-3.57 | $-5.86 | $-4.21 | · | · | · | · | · | · | · | |
| Shares (Basic) | 42,836,129 | 20,592,847 | 11,331,338 | 11,259,615 | · | · | · | · | · | · | · | · | |
| Shares (Diluted) | 42,836,129 | 20,592,847 | 11,331,338 | 11,259,615 | 11,232,576 | · | · | · | · | · | · | · | |
| EBITDA | $-65M | $-49M | $-44M | $-67M | $-47M | $-34M | $-15M | · | · | $-29M | $-21M | $-8M |
Balanço Patrimonial 23
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $50M | $163M | $40M | $24M | $36M | $169M | $564.0K | $19M | $21M | $36M | $40M | $69M | |
| Short-term Investments | $106M | $7M | $26M | $60M | $56M | · | · | $2M | $21M | $5M | $25M | $15M | |
| Prepaid Expense | $4M | $2M | $3M | $2M | $2M | $787.0K | $78.0K | $1M | $1M | $1M | $1M | $1M | |
| Other Current Assets | $65.0K | $2.0K | $37.0K | $127.0K | $34.0K | $52.0K | · | · | · | · | · | · | |
| Current Assets | $160M | $172M | $69M | $86M | $93M | $169M | $764.0K | $23M | $43M | $43M | $67M | $85M | |
| PP&E (Net) | $759.0K | $1M | $1M | $2M | $2M | $1M | $459.0K | $263.0K | $259.0K | $372.0K | $224.0K | $83.0K | |
| PP&E (Gross) | $2M | $2M | $2M | $2M | $2M | $1M | $475.0K | $1M | $971.0K | $937.0K | $665.0K | $467.0K | |
| Accum. Depreciation | $1M | $1M | $824.0K | $483.0K | $236.0K | $119.0K | $16.0K | $827.0K | $712.0K | $565.0K | $441.0K | $384.0K | |
| Goodwill | · | · | · | · | $30M | $30M | · | · | · | · | · | · | |
| Other Non-current Assets | $20.0K | $27.0K | $11.0K | $16.0K | $865.0K | $1M | · | · | $218.0K | $393.0K | $706.0K | $114.0K | |
| Total Assets | $209M | $181M | $79M | $113M | $173M | $203M | $1M | $24M | $44M | $44M | $68M | $85M | |
| Accounts Payable | $3M | $4M | $2M | $2M | $954.0K | $914.0K | $716.0K | $441.0K | $291.0K | $556.0K | $1M | $917.0K | |
| Accrued Liabilities | $6M | $5M | $3M | $3M | $2M | $2M | $3M | $3M | $9M | $5M | $3M | $1M | |
| Current Liabilities | $11M | $11M | $6M | $6M | $4M | $3M | $3M | $3M | $9M | $5M | $4M | $2M | |
| Capital Leases | $2M | $3M | $4M | $5M | $6M | $999.0K | · | · | · | · | · | · | |
| Total Liabilities | $13M | $14M | $11M | $11M | $11M | $4M | $3M | $3M | $9M | $5M | $4M | $2M | |
| Common Stock | $54.0K | $35.0K | $11.0K | $11.0K | $11.0K | $11.0K | $3.0K | · | $18.0K | $17.0K | $16.0K | $16.0K | |
| Paid-in Capital | $499M | $412M | $269M | $263M | $256M | $246M | $11M | $209M | $203M | $198M | $195M | $192M | |
| Retained Earnings | $-302M | $-245M | $-200M | $-160M | $-94M | $-47M | $-13M | $-210M | $-190M | $-160M | $-131M | $-110M | |
| AOCI | $90.0K | $2.0K | $-31.0K | $-688.0K | $-211.0K | · | $3.0K | $5.0K | $-14.0K | · | $-11.0K | $-6.0K | |
| Stockholders' Equity | $196M | $167M | $68M | $102M | $162M | $199M | $-2M | $5M | $35M | $38M | $63M | $82M | |
| Liabilities + Equity | $209M | $181M | $79M | $113M | $173M | $203M | $1M | $24M | $44M | $44M | $68M | $85M | |
| Shares Outstanding | 53,587,260 | 35,044,772 | 11,364,903 | 11,267,389 | 11,235,731 | 11,211,840 | 2,627,533 | 481,091 | 17,674,729 | 16,603,559 | 16,501,500 | 16,448,455 |
Fluxo de Caixa 14
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | · | · | · | · | · | $123.0K | $57.0K | $30.0K | |
| Stock-based Comp | $4M | $4M | $6M | $7M | $10M | $10M | $424.0K | $3M | $3M | $3M | $2M | $459.0K | |
| Deferred Tax | $-11M | $-20M | $-14M | $-9M | $-5M | $-9M | · | · | · | · | · | · | |
| Restructuring | · | · | · | · | · | · | $3M | · | · | · | · | · | |
| Other Non-cash | · | · | · | · | · | · | · | · | · | $1M | $2M | $-7M | |
| Operating Cash Flow | $-56M | $-36M | $-38M | $-26M | $-35M | $-23M | $-5M | $-23M | $-22M | $-24M | $-18M | $-10M | |
| CapEx | $94.0K | $63.0K | $45.0K | $120.0K | $596.0K | $884.0K | $475.0K | $119.0K | $35.0K | $271.0K | $198.0K | $51.0K | |
| Investing Cash Flow | $-139M | $19M | $53M | $15M | $-98M | $3M | $-475.0K | $18M | $-16M | $20M | $-11M | · | |
| Stock Issued | · | · | · | · | · | $74M | · | · | · | · | · | $62M | |
| Stock Repurchased | · | · | $91.0K | $90.0K | $228.0K | · | · | · | · | · | · | · | |
| Net Stock Activity | · | · | $-91.0K | $-90.0K | $-228.0K | $66M | · | · | · | · | · | $62M | |
| Financing Cash Flow | $83M | $140M | $-91.0K | $-90.0K | $-228.0K | $189M | $500.0K | $3M | $23M | $208.0K | $163.0K | · | |
| Net Change in Cash | · | · | · | · | · | · | $-13M | $-2M | $-15M | $-4M | $-29M | $66M | |
| Free Cash Flow | $-56M | $-36M | $-38M | $-27M | $-35M | $-24M | $-16M | · | · | $-24M | $-18M | $-10M |
Lucratividade 5
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | -7391.4% | · | · | · | · | · | -257.1% | |
| Net Margin | · | · | · | · | · | -7291.4% | · | · | · | · | · | -113.4% | |
| EBITDA Margin | · | · | · | · | · | -7391.4% | · | · | · | · | · | -256.1% | |
| ROA | -29.4% | -34.2% | -42.0% | -46.1% | -25.1% | -33.2% | -98.3% | · | · | -51.4% | -28.1% | -7.4% | |
| ROE | -33.7% | -35.8% | -55.6% | -54.7% | -28.4% | -17.2% | -449.1% | · | · | -56.0% | -29.3% | 37.0% |
Liquidez e Solvência 3
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.6 | 15.7 | 11.2 | 15.0 | 21.7 | 58.1 | 12.0 | · | · | 8.4 | 16.1 | 36.2 | |
| Quick Ratio | 14.2 | 15.5 | 10.7 | 14.7 | 21.2 | 57.8 | 10.6 | · | · | 8.1 | 15.8 | 35.8 | |
| Interest Coverage | · | · | · | · | · | -1013.1 | · | · | · | · | · | -8.8 |
Eficiência 1
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | 0.0 | · | · | · | · | · | 0.1 |
Avaliação (TTM) 10
| Métrica | Tendência | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | · | · | · | · | · | · | · | · | · | · | · | $3M | |
| Net Income TTM | $-57M | $-45M | $-40M | $-66M | $-47M | $-34M | $-8M | $-21M | $-30M | $-29M | $-21M | $-3M | |
| Market Cap | $286M | $185M | $21M | $30M | $76M | $271M | $9M | · | · | $1.26B | $10.24B | $6.84B | |
| P/E | -4.0 | -2.4 | -0.5 | -0.5 | -1.6 | · | · | · | · | · | · | · | |
| P/S | · | · | · | · | · | · | · | · | · | · | · | 2321.1 | |
| P/B | 1.5 | 1.1 | 0.3 | 0.3 | 0.5 | 1.4 | 1.4 | · | · | 32.8 | 161.5 | 83.0 | |
| P / Tangible Book | 1.5 | 1.1 | 0.3 | 0.3 | 0.6 | 1.6 | · | · | · | · | · | · | |
| P / Cash Flow | -5.1 | -5.2 | -0.6 | -1.1 | -2.2 | -11.6 | -0.6 | · | · | -53.3 | -582.8 | -684.9 | |
| P / FCF | -5.1 | -5.2 | -0.6 | -1.1 | -2.2 | -11.2 | -0.6 | · | · | -52.7 | -576.3 | -681.5 | |
| Earnings Yield | -25.1% | -41.1% | -190.4% | -218.7% | -62.4% | · | · | · | · | · | · | · |
Demonstração de Resultados 12
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $17M | $14M | $13M | $10M | $11M | $9M | $9M | $8M | $6M | $8M | $6M | $6M | $7M | $5M | $5M | $3M | |
| SG&A Expense | $6M | $6M | $6M | $5M | $6M | $5M | $5M | $4M | $4M | $4M | $5M | $4M | $5M | $5M | $5M | $5M | |
| Operating Expenses | $23M | $20M | $19M | $15M | $17M | $14M | $14M | $12M | $11M | $12M | $11M | $11M | $12M | $10M | $40M | $8M | |
| Operating Income | $-23M | $-20M | $-19M | $-15M | $-17M | $-14M | $-14M | $-12M | $-11M | $-12M | $-11M | $-11M | $-12M | $-10M | $-40M | $-8M | |
| Interest Income | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $756.0K | $820.0K | $840.0K | $846.0K | $687.0K | $542.0K | $283.0K | |
| Other Non-op | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $756.0K | $820.0K | $840.0K | $846.0K | $687.0K | $542.0K | $283.0K | |
| Net Income | $-22M | $-18M | $-17M | $-13M | $-15M | $-12M | $-13M | $-11M | $-10M | $-11M | $-10M | $-10M | $-11M | $-9M | $-39M | $-8M | |
| EPS (Basic) | $-0.36 | $-0.31 | $-0.39 | $-0.31 | $-0.35 | $-0.29 | $-0.25 | $-0.50 | $-0.45 | $-0.97 | $-0.90 | $-0.87 | $-1.00 | $-0.80 | $-3.46 | $-0.68 | |
| EPS (Diluted) | $-0.36 | $-0.31 | $-0.39 | $-0.31 | $-0.35 | $-0.29 | $-0.25 | $-0.50 | $-0.45 | $-0.97 | $-0.90 | $-0.87 | $-1.00 | $-0.80 | $-3.46 | $-0.68 | |
| Shares (Basic) | 61,006,766 | 57,538,833 | -82,414,767 | 42,272,104 | 42,270,855 | 40,707,937 | -34,391,036 | 22,329,772 | 21,233,163 | 11,420,948 | -22,628,260 | 11,347,887 | 11,307,842 | 11,303,869 | -22,511,202 | 11,265,475 | |
| Shares (Diluted) | 61,006,766 | 57,538,833 | -82,414,767 | 42,272,104 | 42,270,855 | 40,707,937 | -34,391,036 | 22,329,772 | 21,233,163 | 11,420,948 | -22,628,260 | 11,347,887 | 11,307,842 | 11,303,869 | -22,511,202 | 11,265,475 | |
| EBITDA | $-23M | $-20M | · | $-15M | $-17M | $-14M | · | $-12M | $-11M | $-12M | · | $-11M | $-12M | $-10M | · | $-8M |
Balanço Patrimonial 23
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $17M | $15M | $50M | $13M | $31M | $91M | $163M | $52M | $90M | $52M | $40M | $34M | $34M | $21M | $24M | $47M | |
| Short-term Investments | $125M | $121M | $106M | $120M | $91M | $33M | $7M | $30M | · | $3M | $26M | $40M | $46M | $66M | $60M | $49M | |
| Prepaid Expense | $4M | $4M | $4M | $3M | $3M | $2M | $2M | $4M | $3M | $3M | $3M | $4M | $4M | $8M | $2M | $2M | |
| Other Current Assets | $230.0K | $17.0K | $65.0K | $218.0K | $78.0K | $16.0K | $2.0K | $3.0K | $4.0K | $3.0K | $37.0K | $2.0K | $1.0K | $127.0K | $127.0K | · | |
| Current Assets | $146M | $140M | $160M | $136M | $125M | $127M | $172M | $85M | $92M | $58M | $69M | $78M | $84M | $95M | $86M | $99M | |
| PP&E (Net) | $1M | $669.0K | $759.0K | $828.0K | $912.0K | $988.0K | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $2M | |
| PP&E (Gross) | · | · | $2M | · | · | · | $2M | · | · | · | $2M | · | · | · | $2M | · | |
| Accum. Depreciation | · | · | $1M | · | · | · | $1M | · | · | · | $824.0K | · | · | · | $483.0K | · | |
| Goodwill | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $30M | |
| Other Non-current Assets | $74.0K | $76.0K | $20.0K | $21.0K | $29.0K | $35.0K | $27.0K | $33.0K | $19.0K | $31.0K | $11.0K | $3M | $3M | $586.0K | $16.0K | $734.0K | |
| Total Assets | $176M | $192M | $209M | $145M | $157M | $169M | $181M | $94M | $102M | $68M | $79M | $88M | $95M | $106M | $113M | $149M | |
| Accounts Payable | $5M | $4M | $3M | $5M | $5M | $2M | $4M | $2M | $1M | $972.0K | $2M | $3M | $2M | $4M | $2M | $456.0K | |
| Accrued Liabilities | $7M | $4M | $6M | $4M | $3M | $4M | $5M | $5M | $3M | $4M | $3M | $3M | $2M | $1M | $3M | $2M | |
| Current Liabilities | $13M | $9M | $11M | $10M | $10M | $7M | $11M | $9M | $6M | $6M | $6M | $7M | $5M | $6M | $6M | $4M | |
| Capital Leases | $1M | $2M | $2M | $2M | $3M | $3M | $3M | $4M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | $6M | |
| Total Liabilities | $15M | $11M | $13M | $12M | $13M | $10M | $14M | $12M | $10M | $10M | $11M | $12M | $10M | $12M | $11M | $9M | |
| Common Stock | $59.0K | $55.0K | $54.0K | $39.0K | $39.0K | $39.0K | $35.0K | $21.0K | $21.0K | $11.0K | $11.0K | $11.0K | $11.0K | $11.0K | $11.0K | $11.0K | |
| Paid-in Capital | $503M | $502M | $499M | $417M | $416M | $415M | $412M | $314M | $313M | $270M | $269M | $267M | $266M | $264M | $263M | $261M | |
| Retained Earnings | $-342M | $-320M | $-302M | $-285M | $-272M | $-257M | $-245M | $-232M | $-221M | $-211M | $-200M | $-190M | $-180M | $-169M | $-160M | $-121M | |
| AOCI | $-363.0K | $-364.0K | $90.0K | $143.0K | $77.0K | $89.0K | $2.0K | $29.0K | · | $-1.0K | $-31.0K | $-165.0K | $-336.0K | $-469.0K | $-688.0K | $-1M | |
| Stockholders' Equity | $161M | $181M | $196M | $132M | $144M | $158M | $167M | $82M | $92M | $58M | $68M | $77M | $85M | $95M | $102M | $139M | |
| Liabilities + Equity | $176M | $192M | $209M | $145M | $157M | $169M | $181M | $94M | $102M | $68M | $79M | $88M | $95M | $106M | $113M | $149M | |
| Shares Outstanding | 59,083,935 | 55,055,582 | 53,587,260 | 38,587,260 | 38,581,863 | 38,577,813 | 35,044,772 | 20,629,772 | 11,364,903 | 11,433,837 | 11,364,903 | 11,364,903 | 11,307,962 | 11,306,753 | 11,267,389 | 11,267,389 |
Fluxo de Caixa 8
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $1M | $1M | $1M | $1M | $903.0K | $833.0K | $904.0K | $931.0K | $1M | $1M | $1M | $1M | $2M | $2M | $1M | $1M | |
| Operating Cash Flow | $-15M | $-21M | $-17M | $-12M | $-12M | $-15M | $-9M | $-8M | $-8M | $-10M | $-9M | $-7M | $-9M | $-13M | $-5M | $-5M | |
| CapEx | · | · | $24.0K | $4.0K | $22.0K | $44.0K | $0 | $8.0K | · | · | $0 | $37.0K | $2.0K | $6.0K | $6.0K | $83.0K | |
| Investing Cash Flow | $18M | $-15M | $-27M | $-7M | $-48M | $-58M | $22M | $-29M | $3M | $23M | $15M | $6M | $22M | $10M | $-18M | $19M | |
| Stock Repurchased | · | · | · | · | · | · | · | · | · | $76.0K | · | $27.0K | $0 | $64.0K | $0 | $18.0K | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $-76.0K | · | · | · | $-64.0K | · | · | |
| Financing Cash Flow | $-26.0K | $1M | $81M | $13.0K | $8.0K | $2M | $98M | $0 | $42M | $-76.0K | $0 | $-27.0K | $0 | $-64.0K | $0 | $-18.0K | |
| Free Cash Flow | · | · | · | · | · | $-15M | · | · | · | · | · | · | · | $-13M | · | · |
Lucratividade 5
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -1575.9% | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Net Margin | -1464.0% | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -1575.9% | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| ROA | -13.0% | -9.9% | · | -11.1% | -11.6% | -10.1% | · | -12.3% | -9.7% | -12.7% | · | -8.3% | -9.0% | -6.8% | · | -4.7% | |
| ROE | -14.2% | -10.5% | · | -12.4% | -12.7% | -11.0% | · | -14.1% | -10.7% | -14.5% | · | -9.1% | -9.8% | -7.3% | · | -5.0% |
Liquidez e Solvência 2
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 11.0 | 15.7 | · | 13.7 | 12.8 | 18.0 | · | 9.8 | 16.3 | 10.5 | · | 11.5 | 17.1 | 14.8 | · | 26.6 | |
| Quick Ratio | 10.7 | 15.2 | · | 13.4 | 12.5 | 17.7 | · | 9.4 | 15.9 | 10.0 | · | 10.9 | 16.3 | 13.5 | · | 26.0 |
Eficiência 1
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Avaliação (TTM) 8
| Métrica | Tendência | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-68M | $-58M | · | $-51M | $-48M | $-44M | · | $-42M | $-42M | $-41M | · | $-38M | $-37M | $-36M | · | $-38M | |
| Market Cap | $226M | $287M | · | $168M | $117M | $164M | · | $38M | $24M | $46M | · | $19M | $27M | $35M | · | $33M | |
| P/E | -2.9 | -4.1 | · | -3.0 | -1.9 | -1.9 | · | -0.7 | -0.6 | -1.1 | · | -0.5 | -0.7 | -1.0 | · | -0.9 | |
| P/B | 1.4 | 1.6 | · | 1.3 | 0.8 | 1.0 | · | 0.5 | 0.3 | 0.8 | · | 0.2 | 0.3 | 0.4 | · | 0.2 | |
| P / Tangible Book | 1.4 | 1.6 | · | 1.3 | 0.8 | 1.0 | · | 0.5 | 0.3 | 0.8 | · | 0.2 | 0.3 | 0.4 | · | 0.3 | |
| P / Cash Flow | · | -13.4 | · | · | · | -11.2 | · | · | · | -4.4 | · | · | · | -2.7 | · | · | |
| P / FCF | · | · | · | · | · | -11.1 | · | · | · | · | · | · | · | -2.7 | · | · | |
| Earnings Yield | -34.8% | -24.2% | · | -33.3% | -52.5% | -51.9% | · | -152.5% | -158.2% | -90.8% | · | -200.6% | -135.6% | -102.2% | · | -113.5% |
Demonstrações Financeiras Demonstração de resultados, balanço patrimonial, fluxo de caixa — anual, últimos 5 anos
Demonstração de Resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Lucro líquido | $-57M | $-45M | $-40M | $-66M | $-47M |
| EPS Diluído | $-1.34 | $-2.17 | $-3.57 | $-5.86 | $-4.21 |
Balanço Patrimonial
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Índice de liquidez corrente | 14.6 | 15.7 | 11.2 | 15.0 | 21.7 |
| Índice de Liquidez Seca | 14.2 | 15.5 | 10.7 | 14.7 | 21.2 |
Fluxo de Caixa
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Fluxo de caixa livre | $-56M | $-36M | $-38M | $-27M | $-35M |
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Investidores institucionais (13F) 127 declarantes · $162.3M total · Em 30 de Junho de 2026
Instituições que relatam a posse desta ação em seu Formulário 13F trimestral da SEC. Apenas posições compradas; um único declarante pode aparecer duas vezes para opções separadas. Grandes posições de compra/venda compensatórias geralmente refletem market-making ou inventário protegido, não convicção direcional.
Atividade institucional — Q2 2026 vs trimestre anterior
| Novas posições | Posições encerradas | Aumentou | Diminuído | Variação líquida de ações |
|---|---|---|---|---|
| 31 (+4 vs trimestre anterior) | 16 (-5 vs trimestre anterior) | 39 (-8 vs trimestre anterior) | 33 (+10 vs trimestre anterior) | +760K |
Comparado a Q1 2026. Os registros do Formulário 13F da SEC devem ser feitos em até 45 dias após o final do trimestre, mais um pequeno período de tolerância para registrantes atrasados — trimestres ainda dentro desse período são ignorados em favor do par mais recente totalmente reportado.
| Instituição | Valor | Ações | % de 13F rastreado | Tipo |
|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | $27.154.562 | 5.207.011 | 16,73% | Ações |
| MILLENNIUM MANAGEMENT LLC | $11.846.454 | 3.101.166 | 7,30% | Ações |
| Velan Capital Investment Management LP | $10.866.571 | 2.844.652 | 6,70% | Ações |
| VANGUARD CAPITAL MANAGEMENT LLC | $8.786.508 | 2.300.133 | 5,41% | Ações |
| Blackstone Inc. | $8.654.263 | 2.265.514 | 5,33% | Ações |
| ORBIMED ADVISORS LLC | $8.480.400 | 2.220.000 | 5,23% | Ações |
| Sio Capital Management, LLC | $7.341.551 | 1.921.872 | 4,52% | Ações |
| ACORN CAPITAL ADVISORS, LLC | $6.693.079 | 1.752.115 | 4,12% | Ações |
| Integral Health Asset Management, LLC | $5.730.000 | 1.500.000 | 3,53% | Ações |
| 5AM Venture Management, LLC | $5.232.567 | 1.369.782 | 3,22% | Ações |
| GEODE CAPITAL MANAGEMENT, LLC | $4.362.540 | 1.141.710 | 2,69% | Ações |
| STATE STREET CORP | $4.080.887 | 1.068.295 | 2,51% | Ações |
| Qube Research & Technologies Ltd | $3.993.871 | 1.045.516 | 2,46% | Ações |
| Balyasny Asset Management L.P. | $3.921.960 | 1.026.691 | 2,42% | Ações |
| BAKER BROS. ADVISORS LP | $3.711.565 | 971.614 | 2,29% | Ações |
| ADAR1 Capital Management, LLC | $3.592.756 | 940.512 | 2,21% | Ações |
| CITADEL ADVISORS LLC | $3.414.045 | 893.729 | 2,10% | Ações |
| BANK OF AMERICA CORP /DE/ | $3.287.679 | 860.649 | 2,03% | Ações |
| DIMENSIONAL FUND ADVISORS LP | $2.389.918 | 625.633 | 1,47% | Ações |
| Point72 Asset Management, L.P. | $2.096.920 | 548.932 | 1,29% | Ações |
| Catalio Capital Management, LP | $1.986.965 | 520.148 | 1,22% | Ações |
| GOLDMAN SACHS GROUP INC | $1.936.106 | 506.834 | 1,19% | Ações |
| Walleye Capital LLC | $1.930.750 | 505.432 | 1,19% | Ações |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1.878.130 | 491.657 | 1,16% | Ações |
| MORGAN STANLEY | $1.833.917 | 480.083 | 1,13% | Ações |
| UBS Group AG | $1.723.538 | 451.188 | 1,06% | Ações |
| VANGUARD FIDUCIARY TRUST CO | $1.278.489 | 334.683 | 0,79% | Ações |
| Verdad Advisers, LP | $1.192.791 | 312.249 | 0,73% | Ações |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $1.129.058 | 295.565 | 0,70% | Ações |
| RENAISSANCE TECHNOLOGIES LLC | $960.730 | 251.500 | 0,59% | Ações |
| OPPENHEIMER & CO INC | $910.543 | 238.362 | 0,56% | Ações |
| Jump Financial, LLC | $775.842 | 203.100 | 0,48% | Ações |
| CIBC WORLD MARKET INC. | $636.011 | 166.495 | 0,39% | Ações |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $603.449 | 157.971 | 0,37% | Ações |
| J. Goldman & Co LP | $515.700 | 135.000 | 0,32% | Ações |
| SUPERSTRING CAPITAL MANAGEMENT LP | $463.966 | 121.457 | 0,29% | Ações |
| Fisher Asset Management, LLC | $380.342 | 99.566 | 0,23% | Ações |
| AMERICAN CENTURY COMPANIES INC | $376.220 | 98.487 | 0,23% | Ações |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $325.961 | 85.330 | 0,20% | Ações |
| TWO SIGMA INVESTMENTS, LP | $266.071 | 69.652 | 0,16% | Ações |
| FMR LLC | $260.012 | 68.066 | 0,16% | Ações |
| XTX Topco Ltd | $244.281 | 63.948 | 0,15% | Ações |
| RHUMBLINE ADVISERS | $241.589 | 63.245 | 0,15% | Ações |
| TRUIST FINANCIAL CORP | $229.200 | 60.000 | 0,14% | Ações |
| Assenagon Asset Management S.A. | $229.024 | 59.954 | 0,14% | Ações |
| Trexquant Investment LP | $227.733 | 59.616 | 0,14% | Ações |
| DEUTSCHE BANK AG\ | $220.464 | 57.713 | 0,14% | Ações |
| ALPS ADVISORS INC | $217.897 | 57.041 | 0,13% | Ações |
| AMERIPRISE FINANCIAL INC | $214.863 | 56.247 | 0,13% | Ações |
| PRUDENTIAL FINANCIAL INC | $193.789 | 50.730 | 0,12% | Ações |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | $191.000 | 50.000 | 0,12% | Ações |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $154.252 | 40.380 | 0,10% | Ações |
| Alyeska Investment Group, L.P. | $151.753 | 39.726 | 0,09% | Ações |
| Quadrature Capital Ltd | $150.199 | 39.319 | 0,09% | Ações |
| Marex Group Ltd | $134.655 | 35.250 | 0,08% | Ações |
| WINTON GROUP Ltd | $125.296 | 32.800 | 0,08% | Ações |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $113.454 | 29.700 | 0,07% | Ações |
| MetLife Investment Management, LLC | $108.404 | 28.378 | 0,07% | Ações |
| MARSHALL WACE, LLP | $106.995 | 28.009 | 0,07% | Ações |
| ALLIANCEBERNSTEIN L.P. | $93.988 | 18.040 | 0,06% | Ações |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $92.043 | 24.095 | 0,06% | Ações |
| WOLVERINE TRADING, LLC | $88.200 | 20.000 | 0,05% | Opção de venda |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $87.478 | 22.900 | 0,05% | Opção de venda |
| CITIGROUP INC | $80.698 | 21.125 | 0,05% | Ações |
| Jain Global LLC | $80.220 | 21.000 | 0,05% | Ações |
| Invesco Ltd. | $78.295 | 20.496 | 0,05% | Ações |
| Vanguard Global Advisers, LLC | $76.885 | 20.127 | 0,05% | Ações |
| PRELUDE CAPITAL MANAGEMENT, LLC | $74.922 | 19.613 | 0,05% | Ações |
| EntryPoint Capital, LLC | $73.673 | 19.286 | 0,05% | Ações |
| LPL Financial LLC | $73.077 | 19.130 | 0,05% | Ações |
| VANGUARD GROUP INC | $70.479 | 13.223 | 0,04% | Ações |
| Squarepoint Ops LLC | $69.234 | 18.124 | 0,04% | Ações |
| IEQ CAPITAL, LLC | $68.489 | 17.929 | 0,04% | Ações |
| Police & Firemen's Retirement System of New Jersey | $67.114 | 17.569 | 0,04% | Ações |
| BARCLAYS PLC | $60.665 | 15.881 | 0,04% | Ações |
| BlackRock, Inc. | $58.950 | 15.432 | 0,04% | Ações |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $56.834 | 14.878 | 0,04% | Ações |
| INTECH INVESTMENT MANAGEMENT LLC | $51.807 | 13.562 | 0,03% | Ações |
| WOLVERINE TRADING, LLC | $51.315 | 11.636 | 0,03% | Ações |
| Mariner, LLC | $45.441 | 11.899 | 0,03% | Ações |
| Bank of New York Mellon Corp | $43.877 | 11.486 | 0,03% | Ações |
| VOYA INVESTMENT MANAGEMENT LLC | $43.812 | 11.469 | 0,03% | Ações |
| D. E. Shaw & Co., Inc. | $42.452 | 11.113 | 0,03% | Ações |
| COMMONWEALTH EQUITY SERVICES, LLC | $42.020 | 11.000 | 0,03% | Ações |
| WELLS FARGO & COMPANY/MN | $41.161 | 10.775 | 0,03% | Ações |
| Essential Partners LLC | $37.444 | 9.802 | 0,02% | Ações |
| MERCER GLOBAL ADVISORS INC /ADV | $34.525 | 9.038 | 0,02% | Ações |
| NORTHERN TRUST CORP | $32.061 | 8.393 | 0,02% | Ações |
| CWM, LLC | $30.458 | 5.846 | 0,02% | Ações |
| NEW YORK STATE COMMON RETIREMENT FUND | $30.178 | 7.900 | 0,02% | Ações |
| BNP PARIBAS FINANCIAL MARKETS | $28.788 | 7.536 | 0,02% | Ações |
| Tower Research Capital LLC (TRC) | $19.062 | 4.990 | 0,01% | Ações |
| Legal & General Group Plc | $17.129 | 4.490 | 0,01% | Ações |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $14.645 | 2.811 | 0,01% | Ações |
| Ameritas Investment Partners, Inc. | $12.598 | 3.298 | 0,01% | Ações |
| Nuveen, LLC | $9.642 | 2.524 | 0,01% | Ações |
| Integrated Wealth Concepts LLC | $6.684 | 1.750 | 0,00% | Ações |
| Arax Advisory Partners | $6.383 | 1.671 | 0,00% | Ações |
| Russell Investments Group, Ltd. | $6.085 | 1.593 | 0,00% | Ações |
| ROYAL BANK OF CANADA | $6.000 | 1.577 | 0,00% | Ações |
Executivos da empresa 40 insiders · 16 diretores · 20 conselheiros
| Investidor com informação privilegiada | Função | Última atividade | Ações detidas | Compras 12m | Vendas 12m | Líquido 12m |
|---|---|---|---|---|---|---|
| Jesse Shefferman | CEO and President | 29 de Junho de 2026 M | 691.832 | 0 | 1 | $-882.160 |
| Timothy P Noyes | President and CEO | 31 de Janeiro de 2019 A | 0 | 0 | 0 | $0 |
| Patrick Fabbio | Chief Financial Officer | 26 de Janeiro de 2026 F | 64.115 | 0 | 0 | $0 |
| Blaine Davis | Chief Financial Officer | 15 de Julho de 2022 F | 20.662 | 0 | 0 | $0 |
| George Arthur Eldridge, | Sr VP, CFO, Treasr, Asst Secy | 18 de Janeiro de 2019 A | 29.132 | 0 | 0 | $0 |
| William Conkling | Chief Commercial Officer | 2 de Junho de 2026 F | 69.992 | 0 | 0 | $0 |
| Jacqueline Zummo | Chief R&D Officer | 8 de Abril de 2026 S | 94.827 | 0 | 2 | $-124.989 |
| Hannah Fry | VP, Controller | 26 de Janeiro de 2026 F | 42.723 | 0 | 0 | $0 |
| Leonardo Viana Nicacio | Chief Medical Officer | 16 de Janeiro de 2026 A | 78.181 | 0 | 0 | $0 |
| Jathin Bandari | Chief Medical Officer | 19 de Janeiro de 2024 A | 56.704 | 0 | 0 | $0 |
| Julio Casoy | Chief Medical Officer | 9 de Janeiro de 2020 A | 45.500 | 0 | 0 | $0 |
| Steven Keith Burke | SVP and Chief Medical Officer | 15 de Março de 2019 G | 26.332 | 0 | 0 | $0 |
| Bradley J Hartman | VP, People | 18 de Janeiro de 2019 A | — | 0 | 0 | $0 |
| Matthew Paul Kowalsky | VP, Legal and Secretary | 18 de Janeiro de 2019 A | 29.479 | 0 | 0 | $0 |
| Scott E. Toner | Senior VP of Commercial | 18 de Janeiro de 2019 A | 23.357 | 0 | 0 | $0 |
| Gottlieb Daniel Philip | VP Corporate Development | 18 de Janeiro de 2019 A | 244 | 0 | 0 | $0 |
| Michael Edward Solomon | Conselheiro | 15 de Junho de 2026 A | 26.500 | 0 | 0 | $0 |
| Jane Huang | Conselheiro | 15 de Junho de 2026 A | — | 0 | 0 | $0 |
| Barry P Flannelly | Conselheiro | 15 de Junho de 2026 A | — | 0 | 0 | $0 |
| Cynthia Smith | Conselheiro | 15 de Junho de 2026 A | — | 0 | 0 | $0 |
| Richard S Levy | Conselheiro | 15 de Junho de 2026 A | 51.000 | 0 | 0 | $0 |
| Roger Garceau | Conselheiro | 15 de Junho de 2026 A | 33.000 | 0 | 0 | $0 |
| Gregory Sargen | Conselheiro | 15 de Junho de 2026 A | 31.000 | 0 | 0 | $0 |
| Luke M Beshar | Conselheiro | 15 de Junho de 2026 A | 198.000 | 0 | 0 | $0 |
| Scott Braunstein | Conselheiro | 9 de Junho de 2020 A | 26.500 | 0 | 0 | $0 |
| John Gordon Freund | Conselheiro | 8 de Novembro de 2019 C | 2.175.882 | 0 | 0 | $0 |
| Hubert Birner | Conselheiro | 8 de Junho de 2018 A | 1.943.059 | 0 | 0 | $0 |
| Paul J Hastings | Conselheiro | 8 de Junho de 2018 A | — | 0 | 0 | $0 |
| Scott A Canute | Conselheiro | 8 de Junho de 2018 A | — | 0 | 0 | $0 |
| Garen G Bohlin | Conselheiro | 8 de Junho de 2018 A | 53.312 | 0 | 0 | $0 |
| Jonathan S Leff | Conselheiro | 8 de Junho de 2018 A | — | 0 | 0 | $0 |
| Brendan O'Leary | Conselheiro | 9 de Junho de 2016 A | 1.387.198 | 0 | 0 | $0 |
| Dmitry Kobyzev | Conselheiro | 2 de Junho de 2015 A | 1.165.344 | 0 | 0 | $0 |
| Gregory D Phelps | Conselheiro | 2 de Junho de 2015 A | — | 0 | 0 | $0 |
| Opaleye, L.P. | Detentor de 10% | 9 de Janeiro de 2020 A | 2.208.472 | 0 | 0 | $0 |
| Martin Sebastian Olivo | — | 10 de Junho de 2021 P | 14.344 | 0 | 0 | $0 |
| Randall Marshall | — | 14 de Setembro de 2020 S | 585.600 | 0 | 0 | $0 |
| Timothy Haines | — | 12 de Novembro de 2019 C | 2.144.517 | 0 | 0 | $0 |
| Abingworth LLP | — | 12 de Novembro de 2019 C | 2.144.517 | 0 | 0 | $0 |
| Stuart A Kingsley | — | 8 de Junho de 2018 A | — | 0 | 0 | $0 |
Executivos de declarações SEC Formulário 3/4/5; líquido = apenas P/V de mercado aberto
Ativistas e proprietários de 5%+ 8 participações
Investidores que apresentaram o Schedule 13D da SEC — propriedade benéfica acima de 5% com a intenção de influenciar o emissor (participações ativistas, campanhas no conselho, M&A). Cada linha mostra o estado mais recente conhecido da posição desse declarante.
| Declarante | Declarado | Participação | Status | Propósito | Declaração |
|---|---|---|---|---|---|
| Deerfield Partners, L.P., Deerfield Private Design Fund III, L.P., Deerfield Private Design Fund IV, L.P., Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt IV, L.P., Deerfield Management Company, L.P., James E. Flynn | 8 de Janeiro de 2021 | — | Declaração inicial | — | SEC |
| Opaleye Management Inc., Opaleye, L.P., James Silverman ×3 declarações | 25 de Setembro de 2020 | — | Declaração inicial | — | SEC |
| Deerfield Special Situations Fund, L.P., Deerfield Partners, L.P., Deerfield Private Design Fund III, L.P., Deerfield Private Design Fund IV, L.P., Deerfield Mgmt, L.P., Deerfield Mgmt III, L.P., Deerfield Mgmt IV, L.P., Deerfield Management Company, L.P., James E. Flynn ×6 declarações | 17 de Janeiro de 2020 | — | Declaração inicial | — | SEC |
| Abingworth LLP, Abingworth Bioventures VI, LP | 17 de Janeiro de 2020 | — | Declaração inicial | M&A / venda | SEC |
| Abingworth LLP 98-051-8585, Abingworth Bioventures VI, LP 98-040-3543 ×3 declarações | 14 de Novembro de 2019 | — | Declaração inicial | Campanha no conselho | SEC |
| TVM Life Science Ventures VI L.P., TVM Life Science Ventures VI GmbH & Co. KG, TVM Life Science Ventures Management VI L.P., Hubert Birner, Stefan Fischer, Helmut Schuehsler ×2 declarações | 2 de Agosto de 2017 | — | Declaração inicial | Investimento passivo | SEC |
| Deerfield Mgmt, L.P., Deerfield Management Company, L.P., Deerfield Mgmt III, L.P., Deerfield Special Situations Fund, L.P., Deerfield Partners, L.P., Deerfield International Master Fund, L.P., Deerfield Private Design Fund III, L.P., James E. Flynn | 29 de Junho de 2017 | — | Declaração inicial | — | SEC |
| Skyline Venture Partners Qualified Purchaser Fund IV, L.P., Skyline Venture Management IV, LLC, John G. Freund, Yasunori Kaneko | 3 de Novembro de 2014 | — | Declaração inicial | Investimento passivo | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Participação em ETFs Detido por 22 ETFs
O peso reflete apenas participações diretas em ações (N-PORT); fundos alavancados ou baseados em derivativos podem deter exposição adicional a swaps não mostrada.
| Fundo | Peso | Unidades | Em | Fonte |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 0,16% | 55.748 NS | 31 de Maio de 2026 | N-PORT |
| IWC · iShares Trust | 0,05% | 175.831 SH | 8 de Agosto de 2026 | Diário |
| VFMO · VANGUARD WELLINGTON FUND | 0,03% | 141.979 SH | 8 de Agosto de 2026 | Diário |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,02% | 91.844 NS | 31 de Maio de 2026 | N-PORT |
| IWN · iShares Trust | 0,01% | 470.658 SH | 8 de Agosto de 2026 | Diário |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,01% | 300.912 SH | 8 de Agosto de 2026 | Diário |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 45.581 SH | 8 de Agosto de 2026 | Diário |
| RSSL · Global X Funds | 0,01% | 22.265 NS | 30 de Abril de 2026 | N-PORT |
| IWM · iShares Trust | 0,01% | 1.336.607 SH | 8 de Agosto de 2026 | Diário |
| DFAS · Dimensional ETF Trust | 0,01% | 179.929 NS | 30 de Abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,01% | 2.419 NS | 31 de Maio de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,01% | 3.715 NS | 30 de Abril de 2026 | N-PORT |
| UWM · ProShares Trust | 0,00% | 1.891 NS | 31 de Maio de 2026 | N-PORT |
| URTY · ProShares Trust | 0,00% | 1.912 NS | 31 de Maio de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 48 NS | 31 de Maio de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 5.791 NS | 30 de Abril de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 18.477 NS | 30 de Abril de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 7.914 NS | 30 de Abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 20.174 NS | 30 de Abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 586.965 SH | 8 de Agosto de 2026 | Diário |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1.657.879 SH | 8 de Agosto de 2026 | Diário |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 3.185 SH | 8 de Agosto de 2026 | Diário |