LXRX Hisse Senedi Özeti Fiyat, piyasa değeri, P/E, EPS, ROE, borç/öz sermaye, 52 haftalık aralık

03
Fiyat $1.82
Piyasa Değeri (MRQ) $813M
P/E (TTM) -12.1
Hisse Başına Kâr (TTM) $-0.15
Gelir (TTM) $41M
ROE (TTM) -40.2%
D/E Borç/Özsermaye (MRQ) 0.3
52 Haftlık Aralık $1–$3

LXRX Hisse Senedi Fiyat Grafiği Teknik göstergeler ile günlük OHLCV — kaydır, yakınlaştır ve görünümünüzü özelleştirin

04
aralık
çubuklar

Çubuk çözünürlüğü seçilen döneme uyum sağlar — bir çubuk için açılış/yüksek/düşük/kapanış değerlerini görmek için grafiğin üzerine gelin.

Hisse bölünmeleri 1
Ex-tarihi Bölünme Tür
21 Mayıs 2015 1-for-7 Ters

Lexicon Pharmaceuticals, Inc. - Common Stock Hakkında Wikipedia'dan şirket genel bakışı

05 · wikidata

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

The company's clinical drug candidates include sotagliflozin (LX4211) for the treatment of type 2 diabetes; LX1033 for the treatment of irritable bowel syndrome and other gastrointestinal disorders; telotristat ethyl (LX1032) for the treatment of the symptoms associated with carcinoid syndrome; and LX2931 for the treatment of autoimmune diseases, such as rheumatoid arthritis.

Company history

Lexicon Pharmaceuticals was founded in September 1995 as a biotech venture of Baylor College of Medicine. The company went public in April 2000 with $220 million initial public offerings. In June, 2001 Lexicon purchased a privately owned small chemical library synthesis company, Coelacanth Corporation in Princeton, New Jersey, which became the site for the company's small molecule and medicinal chemistry efforts. The company's original name was Lexicon Genetics Incorporated, but in 2007, the name changed to Lexicon Pharmaceuticals, Inc. to reflect a renewed focus on drug development.

The company initially focused on using gene knockout technology to define the function of genes. This effort complemented and benefited from the international effort to sequence the human and mouse genomes (see Human Genome Project). Using its proprietary gene trapping and gene targeting technologies, the company created A repository of genetically modified mouse embryonic stem cells, known as OmniBank, and established a large-scale mammalian knockout program to discover the physiological and behavioral functions of the most druggable mammalian genes. The information collected from this program is stored in the company's LexVision database, which contains almost 5,000 gene knockouts studied. Over the years, Lexicon evolved from a genomics company into a drug discovery and development company focused on discovering and developing treatments for human disease. The company currently has multiple drug candidates in various stages of clinical trials.

In 2016, the company was ranked #8 on the Deloitte Fast 500 North America list.

Technology

Lexicon uses patented gene trapping and gene targeting technologies to generate and study knockout mice to discover the physiological and behavioral effects that result from the disruption of a single gene knockout. Because there is a close similarity in gene function and physiology between mice and humans, with a large majority of human genes having a counterpart in the mouse genome, knockout mouse technology has become a powerful tool in the discovery of new medicines.

The value of Lexicon's technology in drug discovery has been described in a retrospective analysis by the scientific journal Nature. The conclusion of this analysis was that, in most cases, there was a direct correlation when comparing the physiological characteristics, or phenotypes, of knockout mice to the therapeutic effect of the 100 best-selling drugs of 2001. The tremendous utility of knockout mouse technology was recognized in 2007 with the Nobel Prize in Physiology or Medicine to Drs. Mario Capecchi, Martin Evans, and Oliver Smithies.

In developing small molecule drugs for its validated targets, Lexicon uses medicinal chemistry known as "click chemistry." Dr. K. Barry Sharpless, who was awarded the 2001 Nobel Prize in Chemistry, developed this tools for the rapid synthesis of novel compounds. Lexicon uses solution-phase chemistry to generate diverse libraries of optically pure compounds that are built using organic reactions that allow the company to generate collections of different compounds and to tailor the compound collections to address various therapeutic target families. Lexicon's medicinal chemists design these libraries by analyzing the chemical structures of drugs that have been proven safe and effective against human disease and using that knowledge in the design of scaffolds and chemical building blocks for the generation of large numbers of new drug-like compounds.

Locations

Lexicon operates from two locations found in Texas and New Jersey. The corporate headquarters are in The Woodlands, Texas just north of Houston. This location serves as Lexicon's primary research facility to discover and validate the company's drug targets and test drug candidates in preclinical research. The company's clinical development and regulatory team is also based at the corporate headquarters.

Lexicon's campus in Princeton, New Jersey is the home of Lexicon's small molecule medicinal chemistry and preclinical development efforts. This site serves as Lexicon's primary medicinal chemistry site to create new chemical entities for therapeutic development.

== References ==

Kaynak: Wikipedia (İngilizce), CC BY-SA 4.0 · Wikipedia'da Görüntüle ↗

Wikidata ↗

sektörHealthcare endüstriPharmaceuticals çalışanlar81 ülkeUS

10 Yıllık Performans Gelir, net kar, marjlar ve EPS trendleri

06
Gelir$50M
2016-12-31 → 2025-12-31
Hisse Başına Kâr$-0.14
2017-12-31 → 2025-12-31
Serbest Nakit Akışı$-68M
2016-12-31 → 2025-12-31
Net kar marjı-147.4%
2016-12-31 → 2025-12-31
Değerleme ve Oranlar 07–12

Değerleme P/E, P/S, P/B, EV/EBITDA oranları — hisse senedi pahalı mı ucuz mu?

Metrik 5 Yıllık trend LXRX 5Y ort. Akran Ortalaması Sonuç
P/E (TTM) -12.15Y ort. ≈-4.2 ≈-4.2 · ·
F/S (TTM) 19.65Y ort. ≈1530.9 ≈1530.9 6.6 Aşırı değerli
F/D (MRQ) 4.75Y ort. ≈4.1 ≈4.1 3.8 Aşırı değerli
EV / EBITDA (TTM) -12.5 · · ·
Price / FCF (Fiyat / Serbest Nakit Akışı) -9.85Y ort. ≈-5.6 ≈-5.6 · ·
Price / Cash Flow (Fiyat / Nakit Akışı) -9.85Y ort. ≈-5.7 ≈-5.7 · ·
EV / Gelir (TTM) 16.3 · · ·
EV / FCF -9.2 · · ·
Price / Tangible Book (Fiyat / Maddi Defter Değeri) 10.65Y ort. ≈6.7 ≈6.7 · ·

Akran ortalaması, metrik başına standartlaştırılmış bir temelde hesaplanır ve bu hisse senedi için gösterilen TTM/MRQ temelini her zaman eşleşmeyebilir.

değer · ≈ 5Y ort. · sektör ortalaması · ortalamaya göre değerlendirme

Kazanç Geçmişi EPS gerçekleşen vs tahmin, sürpriz %, kazanma oranı, bir sonraki kazanç tarihi

14
Ort. Sürpriz 48.2%
Sonraki Rapor Kas 13, 2026
DönemRaporEPS GerçekEPS TahminSürpriz
30 Haziran 2026 Ağu 4, 2026 $-0.07 $-0.05 -36.7%
31 Mart 2026 May 11, 2026 $0.00 $-0.04 100.0%
31 Aralık 2025 $-0.04 $-0.07 43.2%
30 Eylül 2025 $-0.04 $-0.07 40.6%
30 Haziran 2025 $0.01 $-0.08 112.6%
31 Mart 2025 $-0.07 $-0.10 29.6%

Tüm Temeller Tüm metrikler yıla göre — gelir tablosu, bilanço, nakit akışı

15
Gelir Tablosu 16
Metrik Eğilim 202520242023202220212020201920182017201620152014
Revenue $50M$31M$1M$139.0K$298.0K$24M$322M$63M$92M$79M$130M$23M
Cost of Revenue $274.0K$616.0K$85.0K$0$0$2M$3M$2M$2M$0$0·
R&D Expense $61M$84M$59M$53M$55M$154M$92M$100M$152M$164M$95M$89M
SG&A Expense $37M$143M$114M$48M$32M$47M$57M$64M$66M$43M$24M$19M
Operating Expenses $99M$228M$173M$101M$87M$204M$181M$166M$222M$206M$129M$123M
Operating Income $-49M$-197M$-172M$-101M$-87M$-48M$141M$-103M$-131M$-127M$1M$-100M
Interest Expense ···$3M$802.0K$15M$21M$21M$7M$7M$7M$2M
Other Non-op $7M$12M$8M$2M$134.0K$3M$3M$4M$2M$2M$572.0K$2M
Pretax Income ····$-88M$-59M$124M$-121M$-136M$-131M$-5M$-100M
Income Tax ·$0$0$0$0····$0$0$-70.0K
Net Income $-50M$-200M$-177M$-102M$-88M$-59M$130M$-121M$-123M$-131M$-5M$-100M
EPS (Basic) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.23$-1.14$-1.17···
EPS (Diluted) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.16$-1.14$-1.17···
Shares (Basic) 363,053,000320,031,000221,130,000165,733,000145,652,000·······
Shares (Diluted) 363,053,000320,031,000221,130,000165,733,000145,652,000110,841,000116,747,000105,830,000105,237,000···
EBITDA $-48M$-197M$-171M$-100M$-87M$-45M$145M$-100M$-133M$-135M·$-98M
Bilanço 30
Metrik Eğilim 202520242023202220212020201920182017201620152014
Cash & Equivalents $34M$67M$22M$46M$64M$126M$36M$80M$62M$47M$203M$137M
Short-term Investments $62M$171M$148M$92M$23M$26M$236M$80M$249M$300M$318M$202M
Receivables $2M$3M$1M$28.0K$14.0K$395.0K$57M$6M$5M$7M$911.0K$1M
Inventory $281.0K$231.0K$381.0K$0·$0$4M$5M$2M$0··
Other Current Assets $3M$5M$5M$2M$2M$5M$5M$3M$4M$4M$10M$5M
Current Assets $102M$246M$177M$141M$89M$158M$338M$173M$322M$358M$532M$369M
PP&E (Net) $2M$2M$2M$2M$1M$295.0K$14M$16M$18M$19M$21M$1M
PP&E (Gross) $5M$5M$7M$6M$6M$6M$76M$76M$76M$79M$81M$37M
Accum. Depreciation $3M$2M$5M$4M$5M$6M$62M$60M$59M$60M$59M$36M
Goodwill $45M$45M$45M$45M$45M$45M$45M$45M$45M$45M$45M$45M
Intangibles ······$20M$50M$52M$53M$53M$53M
Other Non-current Assets $368.0K$368.0K$828.0K$412.0K$2M$1M$2M$285.0K$429.0K$461.0K$433.0K$3M
Total Assets $185M$298M$229M$194M$137M$204M$418M$284M$437M$476M$652M$471M
Accounts Payable $3M$15M$14M$10M$9M$5M$12M$12M$39M$53M$20M$13M
Accrued Liabilities $13M$30M$17M$13M$13M$30M$42M$21M$12M$32M$25M$10M
Current Liabilities $21M$45M$32M$23M$22M$47M$65M$37M$105M$165M$123M$45M
Capital Leases $7M$5M$5M$5M········
Deferred Tax ······$0$6M$6M$19M$19M$19M
Other Non-current Liabilities $7M$7M$5M$5M$1M$611.0K$1M$238.0K$292.0K$805.0K$14M$24M
Total Liabilities $77M$152M$136M$77M$23M$47M$301M$311M$368M$318M$366M$187M
Long-term Debt $54M$100M·$49M$0$12M$249M$250M$252M$101M$106M$108M
Total Debt $54M$100M$100M·$0$12M$245M$245M$246M$101M·$108M
Common Stock $366.0K$363.0K$245.0K$189.0K$150.0K$142.0K$106.0K$106.0K$106.0K$105.0K$104.0K$104.0K
Paid-in Capital $2.13B$2.12B$1.86B$1.71B$1.61B$1.56B$1.46B$1.45B$1.44B$1.41B$1.40B$1.39B
Retained Earnings $-2.02B$-1.97B$-1.77B$-1.59B$-1.49B$-1.40B$-1.34B$-1.47B$-1.37B$-1.25B$-1.11B$-1.10B
Treasury Stock $5M$5M$3M$2M$8M$5M$4M$3M$2M$3M$3M$2M
AOCI $30.0K$119.0K$31.0K$-428.0K$-10.0K$-6.0K$84.0K$-12.0K$-222.0K$-195.0K$-219.0K$-63.0K
Stockholders' Equity $108M$146M$93M$117M$114M$156M$117M$-26M$68M$168M$286M$284M
Liabilities + Equity $185M$298M$229M$194M$137M$204M$418M$284M$437M$476M$652M$471M
Shares Outstanding 365,848,216363,020,303·189,214,000150,082,000142,289,000106,679,000106,162,000105,711,000104,582,000103,860,000103,663,000
Nakit Akışı 17
Metrik Eğilim 202520242023202220212020201920182017201620152014
D&A $621.0K$534.0K$554.0K$427.0K$292.0K$3M$4M$4M$3M$2M$727.0K$2M
Stock-based Comp $13M$13M$14M$12M$11M$13M$14M$12M$9M$7M$7M$7M
Deferred Tax ···$0$0$0$-6M$0$-13M$0$0$-70.0K
Amort. of Intangibles ·······$2M$2M···
Other Non-cash $-31M$8M$328.0K$1M$-10M$-101M$-28M$-43M$-57M$-44M·$16M
Operating Cash Flow $-68M$-179M$-162M$-89M$-87M$-143M$114M$-149M$-185M$-176M$185M$-76M
CapEx $0$1M$470.0K$1M$1M$87.0K$70.0K$95.0K$228.0K$231.0K$910.0K$80.0K
Investing Cash Flow $113M$-15M$-50M$-71M$2M$381M$-156M$170M$51M$18M$-117M$-108M
Debt Issued $0$0$50M$49M·$0$0$13M$146M$0$0$84M
Net Debt Issued $0$0·$49M$-12M$-217M$-1M$-2M$144M$-2M·$82M
Stock Issued $0$0$139M$94M$37M$70M$0$732.0K$8M$4M$114.0K$202M
Stock Repurchased ·$2M$824.0K$864.0K$3M$1M$941.0K$972.0K$2M$621.0K$357.0K$887.0K
Net Stock Activity $0$-2M$138M$93M$34M$69M$-941.0K$-240.0K$6M$3M·$201M
Financing Cash Flow $-48M$238M$188M$142M$23M$-148M$-2M$-2M$150M$987.0K$-2M$284M
Net Change in Cash $-3M$44M$-24M$-18M$-62M$90M$-44M$19M$15M$-156M$66M$100M
Free Cash Flow $-68M$-180M$-162M$-90M$-88M$-143M$114M$-149M$-186M$-176M·$-76M
Levered FCF ·········$-182M·$-78M
Kârlılık 7
Metrik Eğilim 202520242023202220212020201920182017201620152014
Operating Margin -98.2%-634.2%-14264.9%-72489.2%-29224.8%-199.2%43.9%-163.4%-151.3%-164.6%·-439.2%
Net Margin -101.1%-644.8%-14710.9%-73341.0%-29449.0%-244.1%40.4%-190.7%-142.9%-169.7%·-438.8%
Pretax Margin ····-29449.0%-244.1%38.5%-190.7%-156.9%-169.7%·-439.1%
EBITDA Margin -97.0%-632.5%-14218.9%-72182.0%-29126.9%-187.0%45.1%-157.6%-147.5%-162.1%·-430.7%
ROA -20.8%-75.9%-83.6%-61.6%-51.5%-18.9%37.1%-33.5%-28.3%-25.1%·-26.9%
ROE -39.7%-167.7%-168.5%-88.4%-65.0%-42.8%287.0%-576.0%-117.5%-63.8%·-44.2%
ROIC ·········-53.0%·-25.6%
Likidite ve Solventlik 5
Metrik Eğilim 202520242023202220212020201920182017201620152014
Current Ratio 4.95.45.66.14.03.45.24.72.62.2·8.2
Quick Ratio 4.75.35.46.03.93.35.04.52.52.2·7.6
Debt / Equity 0.50.71.1·0.00.12.1-9.34.70.6·0.4
LT Debt / Equity 0.50.71.1··0.02.0-9.24.40.5·0.3
Interest Coverage ···-36.2-108.6-3.36.8-5.0-19.6-20.9·-44.5
Verimlilik 3
Metrik Eğilim 202520242023202220212020201920182017201620152014
Asset Turnover 0.20.10.00.00.00.10.90.20.20.1·0.1
Inventory Turnover 1.12.00.4··0.90.70.81.9···
Receivables Turnover 17.013.92.36.61.50.810.311.814.719.8·25.0
Hisse Başına 5
Metrik Eğilim 202520242023202220212020201920182017201620152014
Book Value / Share $0.29··$0.62$0.76$1.10$1.10$-0.25$0.49$1.50·$0.39
Revenue / Share $0.14$0.10$0.01·$0.00$0.22$2.76·····
Cash Flow / Share $-0.19$-0.56$-0.73·$-0.60$-1.29$0.97·····
Cash / Share $0.09··$0.24$0.43$0.89$0.34$0.76$0.58$0.45·$0.19
EPS (TTM) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.16$-1.14$-1.17$-0.12$-0.12·
Büyüme Oranları 3
Metrik Eğilim 202520242023202220212020201920182017201620152014
Revenue YoY 60.2%2481.5%766.2%-53.4%-98.8%·······
Revenue CAGR 3Y 610.2%370.7%-63.1%·········
Revenue CAGR 5Y 15.7%···········
Değerleme (TTM) 14
Metrik Eğilim 202520242023202220212020201920182017201620152014
Revenue TTM $50M$31M$1M$139.0K$298.0K$24M$322M$63M$92M$79M$130M$23M
Net Income TTM $-50M$-200M$-177M$-102M$-88M$-59M$130M$-121M$-123M$-131M$-5M$-100M
Market Cap $421M··$361M$591M$487M$443M$705M$1.04B$1.45B·$4.62B
Enterprise Value $378M···$505M$346M$416M$790M$979M$1.20B·$4.39B
P/E -8.2-1.2-1.9-3.1-6.6-6.53.6-5.8-8.4-115.2-110.9·
P/S 8.4··2600.01984.320.31.411.211.418.2·202.3
P/B 3.9··3.15.23.13.8-26.720.09.2·16.3
P / Tangible Book 6.7··5.08.64.4······
P / Cash Flow -6.2··-4.1-6.8-3.43.9-4.7-5.6-8.2·-61.1
P / FCF -6.2··-4.0-6.7-3.43.9-4.7-5.6-8.2·-61.1
EV / EBITDA -7.8···-5.8-7.72.9-7.9-7.3-8.9·-44.6
EV / FCF -5.6···-5.7-2.43.7-5.3-5.3-6.8·-58.0
EV / Revenue 7.6···1693.214.41.312.510.715.2·192.1
Earnings Yield -12.2%-85.1%-52.3%-32.5%-15.2%-15.5%28.0%-17.2%-11.8%-0.87%-0.90%·

En son dönem solda · null değerler · olarak gösterilir

Finansal Tablolar Gelir tablosu, bilanço, nakit akışı — yıllık, son 5 yıl

16
Metrik 2025-12-312024-12-312023-12-312022-12-312021-12-31
Gelir $50M $31M $1M $139.0K $298.0K
Faaliyet Kâr Marjı % -98.2% -634.2% -14264.9% -72489.2% -29224.8%
Net Gelir $-50M $-200M $-177M $-102M $-88M
Seyreltilmiş Hisse Başı Kâr $-0.14 $-0.63 $-0.80 $-0.62 $-0.60

Kurumsal Sahipler (13F) 167 dosya · $890.0M toplam · Tarih itibarıyla 30 Haziran 2026

17

Çeyreklik SEC Form 13F'lerinde bu hisse senedini tuttuklarını bildiren kurumlar. Yalnızca uzun pozisyonlar; tek bir başvuru sahibi, ayrı opsiyon bacakları için iki kez görünebilir. Büyük dengeleyici alım/satım bacakları genellikle piyasa yapımını veya korunmuş envanteri yansıtır, yönlü bir inancı değil.

Sahipler 167
Tutulan Değer $890.0M
Yeni pozisyonlar 43
Çıkan pozisyonlar 27
Kurumsal faaliyet — Q2 2026 ve önceki çeyrek
Yeni pozisyonlar Çıkan pozisyonlar Artırıldı Azaldı Net hisse senedi değişimi
43 (+9 önceki Ç'ye göre) 27 (+14 önceki Ç'ye göre) 39 (-5 önceki Ç'ye göre) 38 (+14 önceki Ç'ye göre) +42.4M

Q1 2026 ile karşılaştırıldı. SEC Form 13F başvuruları, çeyrek sonundan itibaren 45 gün içinde ve geç başvuranlar için kısa bir ek süre içinde tamamlanmalıdır — bu pencere içindeki çeyrekler, en son tam olarak raporlanan çifte tercih edilerek atlanır.

Kurum Değer Hisse senetleri % izlenen 13F'nin Tür
Artal Group S.A. $420.374.549 175.156.062 47,23% Hisse senetleri
FMR LLC $124.276.907 51.782.045 13,96% Hisse senetleri
Siren, L.L.C. $106.328.443 44.303.518 11,95% Hisse senetleri
Sessa Capital IM, L.P. $45.506.006 18.960.836 5,11% Hisse senetleri
BlackRock, Inc. $41.636.978 17.348.741 4,68% Hisse senetleri
VANGUARD CAPITAL MANAGEMENT LLC $23.762.899 9.901.208 2,67% Hisse senetleri
Point72 Asset Management, L.P. $19.803.180 8.251.325 2,23% Hisse senetleri
GEODE CAPITAL MANAGEMENT, LLC $14.989.739 6.244.372 1,68% Hisse senetleri
STATE STREET CORP $11.802.646 4.917.769 1,33% Hisse senetleri
VANGUARD GROUP INC $11.047.532 9.606.549 1,24% Hisse senetleri
VANGUARD PORTFOLIO MANAGEMENT LLC $5.658.598 2.357.749 0,64% Hisse senetleri
NORTHERN TRUST CORP $4.724.686 1.968.619 0,53% Hisse senetleri
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4.696.260 1.956.775 0,53% Hisse senetleri
VANGUARD FIDUCIARY TRUST CO $3.922.970 1.634.571 0,44% Hisse senetleri
CITADEL ADVISORS LLC $3.842.837 1.601.182 0,43% Hisse senetleri
CIBC Private Wealth Group LLC $3.240.347 2.400.257 0,36% Hisse senetleri
Ishara Investments LP $3.050.400 1.271.000 0,34% Hisse senetleri
MILLENNIUM MANAGEMENT LLC $2.722.150 1.134.229 0,31% Hisse senetleri
RENAISSANCE TECHNOLOGIES LLC $2.704.800 1.127.000 0,30% Hisse senetleri
MACKENZIE FINANCIAL CORP $2.312.050 963.354 0,26% Hisse senetleri
ADAR1 Capital Management, LLC $1.800.000 750.000 0,20% Hisse senetleri
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1.672.262 696.776 0,19% Hisse senetleri
UBS Group AG $1.643.312 684.713 0,18% Hisse senetleri
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1.604.400 668.500 0,18% Alım opsiyonu
TWO SIGMA INVESTMENTS, LP $1.544.266 643.444 0,17% Hisse senetleri
Nuveen, LLC $1.407.994 586.664 0,16% Hisse senetleri
JANE STREET GROUP, LLC $1.398.960 582.900 0,16% Alım opsiyonu
Bank of New York Mellon Corp $1.364.893 568.706 0,15% Hisse senetleri
Invesco Ltd. $1.219.370 508.071 0,14% Hisse senetleri
GOLDMAN SACHS GROUP INC $1.165.310 485.546 0,13% Hisse senetleri
Compagnie Lombard Odier SCmA $1.152.000 480.000 0,13% Hisse senetleri
BANK OF AMERICA CORP /DE/ $1.011.117 421.299 0,11% Hisse senetleri
BARCLAYS PLC $929.960 387.483 0,10% Hisse senetleri
CITADEL ADVISORS LLC $886.320 369.300 0,10% Alım opsiyonu
XTX Topco Ltd $858.905 357.877 0,10% Hisse senetleri
CANADA PENSION PLAN INVESTMENT BOARD $618.960 257.900 0,07% Hisse senetleri
RHUMBLINE ADVISERS $616.523 256.885 0,07% Hisse senetleri
DEUTSCHE BANK AG\ $594.068 247.528 0,07% Hisse senetleri
WELLS FARGO & COMPANY/MN $553.128 230.470 0,06% Hisse senetleri
WELLINGTON MANAGEMENT GROUP LLP $431.280 179.700 0,05% Hisse senetleri
CITIGROUP INC $420.492 175.205 0,05% Hisse senetleri
GROUP ONE TRADING LLC $420.031 175.013 0,05% Hisse senetleri
Virtus Investment Advisers, LLC $408.996 170.415 0,05% Hisse senetleri
Headlands Technologies LLC $401.275 167.198 0,05% Hisse senetleri
Ikarian Capital, LLC $395.218 164.674 0,04% Hisse senetleri
Quarry LP $374.846 156.186 0,04% Hisse senetleri
MetLife Investment Management, LLC $351.384 146.410 0,04% Hisse senetleri
MORGAN STANLEY $318.964 132.902 0,04% Hisse senetleri
PANAGORA ASSET MANAGEMENT INC $316.901 132.042 0,04% Hisse senetleri
JPMORGAN CHASE & CO $289.975 109.839 0,03% Hisse senetleri

Tüm 167 kurumsal sahibi göster →

Aktivistler ve %5+ sahipler 11 pozisyon

18

SEC Çizelge 13D dosyalayan yatırımcılar — ihraççı üzerinde nüfuz etme niyetiyle %5'in üzerinde faydalı sahiplik (aktivist hisseler, yönetim kurulu kampanyaları, M&A). Her satır, o başvuru sahibinin pozisyonunun bilinen en son durumunu gösterir.

Başvuru sahibi Dosyalandı Hisse Durum Amaç Başvuru
Invus, L.P., Invus Advisors, L.L.C., Invus Public Equities, L.P., Invus Public Equities Advisors, LLC, Invus Global Management, LLC, Siren, L.L.C., Avicenna Life Sci Master Fund LP, Avicenna Life Sci Master GP LLC, Invus US Partners LLC, Ulys, L.L.C., Raymond Debbane, Artal Participations S.a r.l., Artal International S.C.A., Artal International Management S.A., Artal Group S.A., Westend S.A., Stichting Administratiekantoor Westend, Amaury Wittouck ×7 başvurular 08 Mayıs 2026 39,40% Değişiklik · SEC
Invus, L.P. (2), Invus Advisors, L.L.C. (2), Invus Public Equities, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Global Management, LLC (2), Siren, L.L.C. (2), Artal Participations S.à r.l. (2), Artal International S.C.A. (2), Artal International Management S.A. (2), Artal Group S.A. (2), Westend S.A. (2), Stichting Administratiekantoor Westend (2), Mr. Amaury Wittouck (2), Invus US Partners LLC (2), Ulys, L.L.C. (2), Mr. Raymond Debbane (2) ×15 başvurular 09 Aralık 2024 · İlk başvuru · SEC
24 Şubat 2012 · İlk başvuru · SEC
Raymond Debbane (2), Ulys, L.L.C. (2), Invus Advisors, L.L.C. (2), Invus, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Public Equities, L.P. (2), Invus C.V. (2) 27 Aralık 2011 · İlk başvuru · SEC
14 Kasım 2011 · İlk başvuru · SEC
15 Ağustos 2011 · İlk başvuru · SEC
Raymond Debbane, Ulys, L.L.C., Invus Advisors, L.L.C., Invus, L.P., Invus Public Equities Advisors, LLC, Invus Public Equities, L.P., Invus C.V. 19 Mart 2010 · İlk başvuru Sermaye yapısı SEC
Estate of Gordon A. Cain (, Mary H. Cain ×4 başvurular 05 Ağustos 2005 · İlk başvuru · SEC
Açıklanmayan raporlama kişisi, Açıklanmayan raporlama kişisi, Açıklanmayan raporlama kişisi 08 Ağustos 2003 · İlk başvuru · SEC
Açıklanmayan raporlama kişisi, Açıklanmayan raporlama kişisi, Açıklanmayan raporlama kişisi 18 Temmuz 2003 · İlk başvuru Pasif yatırım SEC
Açıklanmayan raporlama kişisi, Açıklanmayan raporlama kişisi, Açıklanmayan raporlama kişisi, Açıklanmayan raporlama kişisi 19 Mart 2003 · İlk başvuru · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Şirket yöneticileri 49 içeriden öğrenenler · 32 yöneticiler · 19 yönetim kurulu üyeleri

19
İçeriden Öğrenen Rol Son işlem Sahip olunan hisse senetleri Alımlar 12ay Satışlar 12ay Net 12ay
Michael Exton Chief Executive Officer 28 Şubat 2026 M 298.432 0 0 $0
Lonnel Coats Chief Executive Officer 28 Şubat 2024 M 1.098.068 0 0 $0
Arthur T Sands President & CEO 28 Şubat 2014 M 1.021.329 0 0 $0
Scott M Coiante SVP, Chief Financial Officer 28 Şubat 2026 M 105.356 0 0 $0
Ajay Bansal EVP Corp Dev and CFO 02 Haziran 2009 A · 0 0 $0
Julia P Gregory EVP and CFO 07 Şubat 2008 A 50.200 0 0 $0
Jeffrey L Wade President and COO 08 Temmuz 2024 A 324.214 0 0 $0
Rachel Yap Martens SVP, Partnerships & Corp Strat 28 Şubat 2026 M 31.264 0 0 $0
Suma Gopinathan SVP, Discovery 28 Şubat 2026 M 150.132 0 0 $0
Wendy Mcdermott SVP, Human Resources 28 Şubat 2026 M 277.945 0 0 $0
Craig B Granowitz SVP, Chief Medical Officer 28 Şubat 2026 M 323.430 0 0 $0
Lisa Defrancesco SVP, IR and Corp Comm 28 Şubat 2026 M 93.869 0 0 $0
Brian T Crum SVP, General Counsel & Secr. 28 Şubat 2026 M 428.802 0 0 $0
Kristen Alexander VP, Finance and Accounting 28 Şubat 2025 M 76.368 0 0 $0
Alan J Main EVP, Innov & Chem Sciences 28 Şubat 2025 M 339.104 0 0 $0
Brian Corrigan SVP, Regulatory & QA 13 Şubat 2025 A · 0 0 $0
Kenneth B. Kassler-Taub SVP, Regulatory & QA 28 Şubat 2024 M 162.672 0 0 $0
Thomas Garner SVP, Chief Commercial Officer 08 Şubat 2024 A · 0 0 $0
Kiernan Seth VP, Chief Commercial Officer 28 Şubat 2023 M 53.136 0 0 $0
James F Tessmer VP, Finance & Accounting 15 Mart 2021 M 71.766 0 0 $0
Alexander A Santini EVP and CCO 22 Nisan 2020 F 55.584 0 0 $0
Pablo Lapuerta EVP and CMO 22 Nisan 2020 F 85.719 0 0 $0
John Northcott VP, Marketing, Comm Strategy 02 Mart 2015 M 8.235 0 0 $0
Brian P Zambrowicz EVP, Chief Scientific Officer 28 Şubat 2014 M 278.703 0 0 $0
Steven Alan Tragash VP, Corporate Affairs 15 Şubat 2010 A · 0 0 $0
Philip M Brown SVP, Clinical Development 15 Şubat 2010 A 27.306 0 0 $0
James R Piggott PHD SVP of Pharm Bio 07 Şubat 2008 A 0 0 0 $0
Lance K Ishimoto SVP, Intellectual Property 07 Şubat 2008 A 10.200 0 0 $0
Tamar D Howson EVP of Bus Dev 07 Şubat 2008 A · 0 0 $0
Walter F Colbert SVP, HR and Corp Serv 13 Şubat 2007 A · 0 0 $0
Randall B Riggs SVP, Corp Licensing 23 Şubat 2004 M 15.000 0 0 $0
Christophe Person VP Informatics 12 Ocak 2004 M 0 0 0 $0
Ivan Cheung Yönetim kurulu üyesi 03 Haziran 2026 M 89.312 0 0 $0
Diane E. Sullivan Yönetim kurulu üyesi 03 Haziran 2026 M 126.122 0 0 $0
Judith L Swain Yönetim kurulu üyesi 03 Haziran 2026 M 174.486 0 0 $0
Amouyal Philippe Yönetim kurulu üyesi 03 Haziran 2026 M 374.486 0 0 $0
Sam L Barker Yönetim kurulu üyesi 03 Haziran 2026 M 213.771 0 0 $0
Christopher J Sobecki Yönetim kurulu üyesi 03 Haziran 2026 M 293.177 0 0 $0
Raymond Debbane Yönetim kurulu üyesi 03 Haziran 2026 M 1.995.498 7 0 $723.048
Robert J Lefkowitz MD Yönetim kurulu üyesi 13 Mayıs 2024 A 48.364 0 0 $0
Frank Palantoni Yönetim kurulu üyesi 21 Mayıs 2023 M 40.332 0 0 $0
Alan S Nies Yönetim kurulu üyesi 21 Mayıs 2023 M 41.046 0 0 $0
Invus C.V. Yönetim kurulu üyesi 31 Aralık 2020 J 0 0 0 $0
Kathleen M Wiltsey Yönetim kurulu üyesi 24 Nisan 2009 A · 0 0 $0
Clayton Stuart Rose Yönetim kurulu üyesi 26 Haziran 2007 P 25.000 0 0 $0
Barry Mills Yönetim kurulu üyesi 26 Nisan 2007 A 25.000 0 0 $0
Patricia M Cloherty Yönetim kurulu üyesi 27 Nisan 2006 A · 0 0 $0
Thomas C Caskey Yönetim kurulu üyesi 13 Ekim 2005 P 6.300 0 0 $0
Praveen Tyle · 28 Şubat 2021 M 120.791 0 0 $0

SEC Form 3/4/5 başvurularından yöneticiler; net = yalnızca açık piyasa Alış/Satış

ETF sahipliği 16 ETF'ler tarafından tutuluyor

20

Ağırlık yalnızca doğrudan öz sermaye varlıklarını (N-PORT) yansıtır; kaldıraçlı veya türev tabanlı fonlar gösterilmeyen ek swap pozisyonlarına sahip olabilir.

Fon Ağırlık Birimler Tarih itibarıyla Kaynak
BBC · ETFis Series Trust I 0,81% 161.882 NS 31 Temmuz 2026 N-PORT
PILL · Direxion Shares ETF Trust 0,45% 40.310 NS 31 Temmuz 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0,42% 53.319 SH 02 Ekim 2026 Günlük
IWC · iShares Trust 0,12% 842.323 SH 11 Eylül 2026 Günlük
VTWG · VANGUARD SCOTTSDALE FUNDS 0,04% 266.401 SH 19 Ağustos 2026 Günlük
IWO · iShares Trust 0,03% 2.343.443 SH 11 Eylül 2026 Günlük
VTWO · VANGUARD SCOTTSDALE FUNDS 0,02% 1.432.882 SH 19 Ağustos 2026 Günlük
RSSL · Global X Funds 0,02% 118.391 NS 31 Temmuz 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,02% 255.130 SH 02 Ekim 2026 Günlük
IWM · iShares Trust 0,02% 6.319.224 SH 11 Eylül 2026 Günlük
VXF · VANGUARD INDEX FUNDS 0,01% 2.594.934 SH 19 Ağustos 2026 Günlük
VHT · VANGUARD WORLD FUND 0,01% 637.561 SH 19 Ağustos 2026 Günlük
WSML · iShares Trust 0,01% 17.992 SH 11 Eylül 2026 Günlük
IWV · iShares Trust 0,00% 85.389 SH 03 Eylül 2026 Günlük
VTI · VANGUARD INDEX FUNDS 0,00% 7.083.651 SH 19 Ağustos 2026 Günlük
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 20.905 SH 19 Ağustos 2026 Günlük

LXRX Analist Uzlaşması Boğa ve ayı analist görüşleri, 12 aylık fiyat hedefi, yukarı yönlü potansiyel

21
derecelendirme · 11 analist AL
Medyan hedef $4.55 +150,0%
3 27,3% Güçlü Al
5 45,5% Al
3 27,3% Tut
0 0,0% Sat
0 0,0% Güçlü Sat

12 Aylık Fiyat Hedefi

6 analist · 2026-09-30

Ortalama hedef $4.55 +149,8%

← Tüm hedeflerin altında Mevcut fiyat $1.82
Düşük$2.00 Ortalama$4.55 Yüksek$8.00

Akran karşılaştırması (GICS alt sektörü) Anahtar metrikler sektördeki benzerlerine karşı

22

Mali yıl bazında, fiyatlar her şirketin son mali yıl kapanışına göredir.

Hisse Sembolü Piyasa Değeri P/E Gelir YoY Net Kar Marjı ROE Brüt Kar Marjı
LXRX $421M -8.2 60.2% -101.1% -39.7% ·
ANRO $568M -8.1 · · -46.1% ·
ALMS · -3.4 · -1011.8% -61.9% ·
APMD · · · · · ·
SGP · · · · 50.0% ·
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
ACRS $363M -5.7 -58.2% -829.6% -55.3% ·
ZVRA $509M 6.6 350.9% 78.2% 61.2% ·
AQST $788M -8.3 -22.6% -188.1% 157.7% ·
PHAT $1.18B -5.5 216.9% -126.4% 52.4% 87.1%

Son Haberler Bu şirketten bahseden son manşetler

23

Metriklerim Kişisel izleme listeniz — Tam Temeller'den seçilen satırlar

26

Sizin için önemli olan metrikleri seçin — Yukarıdaki Tam Temeller bölümündeki herhangi bir satırın yanındaki + işaretine tıklayın.

Seçiminiz kaydedildi ve tüm hisse senetlerinde sizinle birlikte gelir.

Kaynak: SEC 10-Q dosyalandı Ağu 6, 2026