PBYI Puma Biotechnology Inc - Common Stock

NASDAQ · Biotechnology · SEC EDGAR'da Görüntüle ↗
$9,41
Fiyat · Ağu 19, 2026
Temel veriler itibarıyla Ağu 6, 2026

Puma Biotechnology Inc - Common Stock Hakkında Wikipedia'dan şirket genel bakışı

Puma Biotechnology is a publicly traded biopharmaceutical company headquartered in Los Angeles, CA.

Devamını oku

Puma Biotechnology is a publicly traded biopharmaceutical company (NASDAQ: PBYI) headquartered in Los Angeles, CA.

Creation

Puma was founded in September 2010 by Alan Auerbach to identify and in-license compounds that were already in clinical development. This was the same business plan Auerbach had followed at Cougar Biotechnology, which he founded in 2003, and through which he in-licensed abiraterone acetate from BTG plc. Cougar further developed abiraterone before the company was sold to Johnson & Johnson in 2009. Auerbach brought many Cougar employees with him after founding Puma in 2010.

Funding for development

In August 2011 Puma licensed two drug candidates from Pfizer: neratinib (PB272) and an analog (PB357) to serve as a backup candidate.

As part of an approximately $60 million financing round in October 2011, Puma entered into a reverse merger with the shell company Innovative Acquisitions Corp., formed in 2007. In April 2012 the company's stock began trading over the counter. In October 2012 the company raised around $138 million and its shares were listed on the New York Stock Exchange.

In 2016 Puma discovered that Robert Gadimian, senior director of regulatory affairs, had twice bought and sold stock based on his knowledge of unpublished clinical trial results; Puma quickly fired him after conducting an internal investigation and reported the insider trading to the SEC.

Approval and licensing of neratinib

In March 2016 Puma held a pre-NDA meeting with the FDA in which the FDA raised concerns about the design and conduct of clinical trials that Puma had run and recommended that Puma not file the NDA with that data.

Puma did file the NDA, and in May 2017 an FDA review panel recommended that the FDA approve neratinib but raised concerns that the intended use was too broad and should be limited to people with specific mutations. The FDA's briefing document to the panel had raised concerns about the marginal benefit of the drug and the side effects. In July 2017 the FDA approved neratinib for use in preventing the return of breast cancer after treatment that included trastuzumab and without any need for genetic testing, and with warnings about the risk of severe diarrhea. U.S. sales of neratinib totaled $200.5 million in 2018.

In January 2018 an EMA committee gave a negative review to neratinib. In June 2018 this same EMA committee recommended the approval of neratinib, which received European Commission (EC) approval in September 2018.

In 2019 Puma licensed commercialization rights in Europe and part of Africa to Pierre Fabre for an upfront payment of $60 million and milestone payments that could reach $345 million. Previously, Puma licensed rights in Greater China to CANbrdige Life Sciences, rights in Israel to Medison Pharma, rights in Canada to Knight Therapeutics, rights in South East Asian to Specialised Therapeutics and rights in Latin America to Pint Pharma.

== References ==

Kaynak: Wikipedia (İngilizce), CC BY-SA 4.0 · Wikipedia'da Görüntüle ↗

Wikidata ↗

PBYI Hisse Senedi Özeti Fiyat, piyasa değeri, P/E, EPS, ROE, borç/öz sermaye, 52 haftalık aralık

Fiyat
$9.41
Piyasa Değeri
$479M
P/E (TTM)
15.6
EPS (TTM)
$0.61
Gelir (TTM)
$228M
Temettü Verimi
ROE
26.5%
D/E Borç/Özsermaye
0.2
52 Haftlık Aralık
$4 – $10

PBYI Hisse Senedi Fiyat Grafiği Teknik göstergeler ile günlük OHLCV — kaydır, yakınlaştır ve görünümünüzü özelleştirin

10 Yıllık Performans Gelir, net kar, marjlar ve EPS trendleri

Gelir ve Net Gelir $228M
9-point trend, +724.9%
2017-12-31 2025-12-31
Hisse Başına Kâr $0.61
6-point trend, +140.1%
2020-12-31 2025-12-31
Serbest Nakit Akışı $42M
8-point trend, +128.6%
2016-12-31 2025-12-31
Marjlar 13.6%

Değerleme P/E, P/S, P/B, EV/EBITDA oranları — hisse senedi pahalı mı ucuz mu?

Metrik
5 Yıllık trend
PBYI
Akran Ortalaması
P/E (TTM)
5-point trend, +244.5%
15.6
17.4
P/S (TTM) (F/S (TTM))
5-point trend, +172.8%
2.1
52.3
P/B (F/D)
5-point trend, +104.6%
3.7
4.8
EV / EBITDA
5-point trend, -94.3%
10.8
Price / FCF (Fiyat / Serbest Nakit Akışı)
5-point trend, +21.8%
11.5

Kârlılık Brüt, faaliyet ve net kâr marjları; ROE, ROA, ROIC

Metrik
5 Yıllık trend
PBYI
Akran Ortalaması
Operating Margin (Faaliyet Kâr Marjı)
5-point trend, +3102.0%
16.3%
Net Profit Margin (Net Kâr Marjı)
5-point trend, +218.3%
13.6%
-670.1%
ROA
5-point trend, +217.1%
14.5%
-41.1%
ROE
5-point trend, -93.9%
26.5%
-52.6%
ROIC
5-point trend, +1437.7%
21.2%

Finansal Sağlık Borç, likidite, solventlik — bilanço gücü

Metrik
5 Yıllık trend
PBYI
Akran Ortalaması
Debt / Equity (Borç / Öz Sermaye)
5-point trend, +100.4%
0.2
Current Ratio (Cari Oran)
5-point trend, +56.7%
2.0
7.7
Quick Ratio (Cari Oran)
5-point trend, +77.9%
1.9

Büyüme Gelir, EPS ve net gelir büyümesi: YOY, 3 Yıllık CAGR, 5 Yıllık CAGR

Metrik
5 Yıllık trend
PBYI
Akran Ortalaması
Revenue YoY (Gelir Yıllık Bazda)
5-point trend, -9.8%
-0.91%
Revenue CAGR 3Y (Gelir 3 Yıllık Bileşik Büyüme Oranı)
5-point trend, -9.8%
0.05%
Revenue CAGR 5Y (Gelir 5 Yıllık Bileşik Büyüme Oranı)
5-point trend, -9.8%
0.29%
EPS YoY (EPS YB)
5-point trend, +184.7%
-1.6%
Net Income YoY (Net Gelir Yıllık Bazda)
5-point trend, +206.8%
2.8%

Hisse Başı Metrikler Hisse Başı Kâr, hisse başına defter değeri, hisse başına nakit akışı, hisse başına temettü

Metrik
5 Yıllık trend
PBYI
Akran Ortalaması
EPS (Diluted) (Hisse Başına Kar (Seyreltilmiş))
5-point trend, +184.7%
$0.61

Sermaye Verimliliği Aktif devir hızı, stok devir hızı, alacak devir hızı

Metrik
5 Yıllık trend
PBYI
Akran Ortalaması

PBYI Analist Uzlaşması Boğa ve ayı analist görüşleri, 12 aylık fiyat hedefi, yukarı yönlü potansiyel

SAT 6 analist
  • Güçlü Al 0 0,0%
  • Al 0 0,0%
  • Tut 3 50,0%
  • Sat 1 16,7%
  • Güçlü Sat 2 33,3%

12 Aylık Fiyat Hedefi

1 analist · 2026-08-18
Medyan hedef $6.00 -36,2%
Ortalama hedef $6.00 -36,2%

Kazanç Geçmişi EPS gerçekleşen vs tahmin, sürpriz %, kazanma oranı, bir sonraki kazanç tarihi

Ort. Sürpriz
0.07%
Dönem EPS Gerçek EPS Tahmin Sürpriz
30 Haziran 2026 $0.16 $0.04 0.12%
31 Mart 2026 $-0.07 $-0.13 0.06%
31 Aralık 2025 $0.26 $0.23 0.03%
30 Eylül 2025 $0.17 $0.05 0.12%
30 Haziran 2025 $0.12 $0.10 0.02%
31 Mart 2025 $0.06 $-0.02 0.08%

Akran karşılaştırması (GICS alt sektörü) Anahtar metrikler sektördeki benzerlerine karşı

Hisse Sembolü Piyasa Değeri P/E Gelir YoY Net Kar Marjı ROE Brüt Kar Marjı
PBYI $300M 9.8 -0.91% 13.6% 26.5%
CABA $220M -1.0 -115.5%
QTTB $43M 1.4 55.5% 200.3%
OCGN $422M -5.6 8.8% -1537.4% 1488.8%
LRMR $317M -2.2 -167.4%
RZLT $388M -4.6 -56.9%
BNTC $307M -11.1 -43.8%
EDIT $201M -1.1 25.4% -395.0% -688.8%
CMPX $958M -45.9%
PROK 1075.0% -7725.2% 6.9%

Tüm Temeller Tüm metrikler yıla göre — gelir tablosu, bilanço, nakit akışı

Gelir Tablosu 17
PBYI için Yıllık Gelir Tablosu verileri
Metrik Eğilim 202520242023202220212020201920182017
Revenue 9-point trend, +724.9% $228M $230M $236M $228M $253M $225M $272M $251M $28M
Cost of Revenue 9-point trend, +943.7% $58M $64M $63M $55M $64M $39M $37M $35M $6M
R&D Expense 5-point trend, -65.4% · · · · $72M $98M $133M $165M $208M
SG&A Expense 9-point trend, -33.6% $71M $80M $90M $90M $116M $118M $142M $146M $107M
Operating Expenses 9-point trend, -40.3% $191M $200M $203M $204M $252M $256M $311M $346M $320M
Operating Income 9-point trend, +112.8% $37M $31M $33M $24M $1M $-30M $-39M $-95M $-292M
Interest Expense 7-point trend, +1751.4% · · $13M $12M $13M $14M $15M $11M $720.0K
Interest Income 9-point trend, +224.7% $4M $5M $3M $813.0K $160.0K $489.0K $3M $2M $1M
Other Non-op 9-point trend, +1116.8% $1M $862.0K $759.0K $-28.0K $292.0K $367.0K $128.0K $-714.0K $-101.0K
Pretax Income 8-point trend, +131.5% $36M $24M $23M $457.0K $-29M $-60M $-76M $-114M ·
Income Tax 9-point trend, +4671000.00 $5M $-6M $1M $455.0K $324.0K $207.0K $53.0K $17.0K $0
Net Income 9-point trend, +110.7% $31M $30M $22M $2.0K $-29M $-60M $-76M $-114M $-292M
EPS (Basic) 7-point trend, +100.0% $0.62 $0.62 $0.46 $0.00 $-0.72 $-1.52 $-75595.00 · ·
EPS (Diluted) 6-point trend, +140.1% $0.61 $0.62 $0.45 $0.00 $-0.72 $-1.52 · · ·
Shares (Basic) 6-point trend, +26.4% 50,011,485 48,648,701 47,134,331 44,674,501 40,638,852 39,576,107 · · ·
Shares (Diluted) 6-point trend, +28.0% 50,653,283 49,100,433 47,550,852 44,929,998 40,638,852 39,576,107 · · ·
EBITDA 9-point trend, +112.8% $37M $31M $33M $24M $1M $-30M $-39M $-95M $-292M
Bilanço 26
PBYI için Yıllık Bilanço verileri
Metrik Eğilim 202520242023202220212020201920182017
Cash & Equivalents 9-point trend, -63.7% $30M $69M $85M $76M $63M $85M $60M $108M $82M
Short-term Investments 8-point trend, +19.1% $68M $32M $11M $5M $19M $8M $52M $57M ·
Receivables 9-point trend, +454.9% $54M $32M $48M $40M $33M $26M $29M $21M $10M
Inventory 9-point trend, +171.8% $6M $9M $7M $5M $7M $3M $3M $3M $2M
Prepaid Expense 9-point trend, -72.0% $4M $6M $4M $6M $9M $11M $13M $12M $13M
Other Current Assets 8-point trend, -85.7% $256.0K $91.0K $912.0K $2M $447.0K $4M $323.0K $2M ·
Current Assets 9-point trend, +52.9% $163M $148M $156M $134M $140M $146M $166M $203M $106M
PP&E (Net) 9-point trend, -95.8% $187.0K $515.0K $855.0K $1M $2M $2M $3M $4M $4M
PP&E (Gross) 9-point trend, -43.9% $5M $8M $9M $9M $9M $9M $9M $9M $9M
Accum. Depreciation 9-point trend, +13.2% $5M $8M $8M $7M $7M $6M $6M $5M $4M
Intangibles 9-point trend, -14.4% $41M $51M $61M $71M $66M $74M $40M $44M $48M
Total Assets 9-point trend, +30.7% $216M $213M $231M $222M $227M $244M $235M $259M $166M
Accounts Payable 9-point trend, -81.7% $5M $6M $7M $6M $11M $12M $19M $21M $28M
Accrued Liabilities 9-point trend, +63.2% $50M $37M $53M $53M $93M $61M $69M $46M $31M
Current Liabilities 9-point trend, +39.3% $81M $96M $99M $77M $110M $114M $91M $67M $58M
Capital Leases 7-point trend, -79.2% $5M $1M $7M $12M $16M $20M $23M · ·
Other Non-current Liabilities 3-point trend, -100.0% $0 $121.0K $121.0K · · · · · ·
Total Liabilities 9-point trend, -23.4% $86M $121M $177M $200M $229M $250M $217M $225M $112M
Long-term Debt 9-point trend, -53.2% $23M $68M $102M $102M $102M $84M $95M $152M $48M
Total Debt 6-point trend, -77.1% $23M $67M $100M $98M $97M $98M · · ·
Common Stock 9-point trend, +25.0% $5.0K $5.0K $5.0K $5.0K $4.0K $4.0K $4.0K $4.0K $4.0K
Retained Earnings 9-point trend, -17.9% $-1.28B $-1.31B $-1.35B $-1.37B $-1.37B $-1.34B $-1.28B $-1.20B $-1.09B
AOCI 8-point trend, +400.0% $36.0K $6.0K $-4.0K $0 $-2.0K $0 $62.0K $-12.0K ·
Stockholders' Equity 9-point trend, +144.5% $130M $92M $53M $22M $-2M $-6M $17M $34M $53M
Liabilities + Equity 9-point trend, +30.7% $216M $213M $231M $222M $227M $244M $235M $259M $166M
Shares Outstanding 9-point trend, +34.1% 50,408,023 49,105,834 47,646,787 46,345,660 41,175,507 40,086,387 39,203,304 38,325,037 37,594,851
Nakit Akışı 14
PBYI için Yıllık Nakit Akışı verileri
Metrik Eğilim 202520242023202220212020201920182017
D&A 9-point trend, +289.1% $11M $12M $12M $10M $11M $10M $8M $7M $3M
Stock-based Comp 9-point trend, -93.6% $7M $8M $10M $12M $33M $37M $57M $87M $109M
Deferred Tax 4-point trend, +3245000.00 $3M $-7M $0 $0 · · · · ·
Amort. of Intangibles 9-point trend, +506.2% $10M $10M $8M $8M $8M $6M $4M $4M $2M
Operating Cash Flow 9-point trend, +124.2% $42M $39M $27M $-16M $21M $773.0K $22M $-24M $-172M
CapEx 9-point trend, -83.5% $71.0K $56.0K $140.0K $0 $0 $46.0K $306.0K $439.0K $431.0K
Investing Cash Flow 9-point trend, -134.4% $-36M $-20M $-19M $7M $-11M $33M $5M $-58M $-15M
Debt Issued 3-point trend, -50.0% · · · · · · $25M $105M $50M
Net Debt Issued 3-point trend, -50.0% · · · · · · $25M $105M $50M
Financing Cash Flow 9-point trend, -160.2% $-45M $-34M $0 $12M $-32M $-10M $-67M $108M $75M
Net Change in Cash 9-point trend, +64.9% $-40M $-15M $8M $4M $-22M $24M $-40M $27M $-113M
Taxes Paid $1M · · · · · · · ·
Free Cash Flow 7-point trend, +124.1% $42M $39M $27M $-16M $21M · · $-25M $-173M
Levered FCF 3-point trend, +84.1% · · $14M $-16M $8M · · · ·
Kârlılık 7
PBYI için Yıllık Kârlılık verileri
Metrik Eğilim 202520242023202220212020201920182017
Operating Margin 9-point trend, +101.5% 16.3% 13.4% 13.9% 10.4% 0.51% -13.5% -14.4% -37.7% -1056.1%
Net Margin 9-point trend, +101.3% 13.6% 13.1% 9.2% 0.00% -11.5% -26.7% -27.8% -45.2% -1054.6%
Pretax Margin 6-point trend, +159.0% 15.7% 10.5% 9.6% 0.20% -11.4% -26.6% · · ·
EBITDA Margin 9-point trend, +101.5% 16.3% 13.4% 13.9% 10.4% 0.51% -13.5% -14.4% -37.7% -1056.1%
ROA 9-point trend, +110.4% 14.5% 13.6% 9.5% 0.00% -12.4% -25.0% -30.6% -53.5% -139.6%
ROE 9-point trend, +111.9% 26.5% 37.1% 46.8% 0.01% 435.8% 1873.7% -436.4% -283.2% -221.9%
ROIC 6-point trend, +164.2% 21.2% 24.4% 20.3% 0.09% 1.4% -33.0% · · ·
Likidite ve Solventlik 5
PBYI için Yıllık Likidite ve Solventlik verileri
Metrik Eğilim 202520242023202220212020201920182017
Current Ratio 9-point trend, +9.8% 2.0 1.5 1.6 1.7 1.3 1.3 1.8 3.0 1.8
Quick Ratio 9-point trend, +18.8% 1.9 1.4 1.4 1.6 1.0 1.0 1.5 2.8 1.6
Debt / Equity 6-point trend, +101.0% 0.2 0.7 1.9 4.5 -39.7 -16.5 · · ·
LT Debt / Equity 6-point trend, +100.0% 0.0 0.2 1.2 4.5 -39.7 -14.1 · · ·
Interest Coverage 7-point trend, +100.6% · · 2.4 2.0 0.1 -2.2 -2.6 -8.6 -406.1
Verimlilik 3
PBYI için Yıllık Verimlilik verileri
Metrik Eğilim 202520242023202220212020201920182017
Asset Turnover 9-point trend, +702.9% 1.1 1.0 1.0 1.0 1.1 0.9 1.1 1.2 0.1
Inventory Turnover 7-point trend, +48.7% 8.2 8.2 10.8 9.5 12.1 · · 14.9 5.5
Receivables Turnover 9-point trend, -6.9% 5.3 5.8 5.3 6.3 8.7 8.3 11.0 16.5 5.7
Hisse Başına 5
PBYI için Yıllık Hisse Başına verileri
Metrik Eğilim 202520242023202220212020201920182017
Book Value / Share 9-point trend, +82.4% $2.59 $1.88 $1.12 $0.52 $-0.06 $-0.15 $0.45 $0.90 $1.42
Revenue / Share 4-point trend, -11.2% $4.51 $4.69 $4.96 $5.08 · · · · ·
Cash Flow / Share 4-point trend, +334.3% $0.83 $0.79 $0.57 $-0.35 · · · · ·
Cash / Share 9-point trend, -72.9% $0.59 $1.41 $1.78 $1.85 $1.57 $2.13 $1.53 $2.83 $2.17
EPS (TTM) 6-point trend, +140.1% $0.61 $0.62 $0.45 $0.00 $-0.72 $-1.52 · · ·
Büyüme Oranları 6
PBYI için Yıllık Büyüme Oranları verileri
Metrik Eğilim 202520242023202220212020201920182017
Revenue YoY 5-point trend, -107.3% -0.91% -2.2% 3.3% -9.9% 12.5% · · · ·
Revenue CAGR 3Y 3-point trend, -96.8% 0.05% -3.1% 1.5% · · · · · ·
Revenue CAGR 5Y 0.29% · · · · · · · ·
EPS YoY 2-point trend, -104.3% -1.6% 37.8% · · · · · · ·
Net Income YoY 3-point trend, -100.0% 2.8% 40.2% 1079450.0% · · · · · ·
Net Income CAGR 3Y 2396.3% · · · · · · · ·
Değerleme (TTM) 14
PBYI için Yıllık Değerleme (TTM) verileri
Metrik Eğilim 202520242023202220212020201920182017
Revenue TTM 9-point trend, +724.9% $228M $230M $236M $228M $253M $225M $272M $251M $28M
Net Income TTM 9-point trend, +110.7% $31M $30M $22M $2.0K $-29M $-60M $-76M $-114M $-292M
Market Cap 9-point trend, -91.9% $300M $150M $206M $174M $122M $411M $343M $780M $3.72B
Enterprise Value 6-point trend, -46.0% $225M $116M $210M $191M $137M $416M · · ·
P/E 5-point trend, +244.5% 9.8 4.9 9.6 · -4.2 -6.8 · · ·
P/S 9-point trend, -99.0% 1.3 0.6 0.9 0.8 0.5 1.8 1.3 3.1 134.2
P/B 9-point trend, -96.7% 2.3 1.6 3.9 8.1 -49.8 -69.1 19.6 22.7 69.7
P / Tangible Book 2-point trend, -7.7% 3.4 3.7 · · · · · · ·
P / Cash Flow 9-point trend, +133.3% 7.2 3.8 7.6 -11.0 5.9 532.1 15.3 -32.4 -21.5
P / FCF 7-point trend, +133.4% 7.2 3.9 7.7 -11.0 5.9 · · -31.8 -21.5
EV / EBITDA 6-point trend, +144.0% 6.0 3.7 6.4 8.1 106.1 -13.7 · · ·
EV / FCF 5-point trend, -18.7% 5.4 3.0 7.8 -12.1 6.6 · · · ·
EV / Revenue 6-point trend, -46.7% 1.0 0.5 0.9 0.8 0.5 1.8 · · ·
Earnings Yield 6-point trend, +169.2% 10.2% 20.3% 10.4% 0.00% -23.7% -14.8% · · ·

Finansal Tablolar Gelir tablosu, bilanço, nakit akışı — yıllık, son 5 yıl

Gelir Tablosu
2025-12-312024-12-312023-12-312022-12-312021-12-31
Gelir $228M$230M$236M$228M$253M
Faaliyet Kâr Marjı % 16.3%13.4%13.9%10.4%0.51%
Net Gelir $31M$30M$22M$2.0K$-29M
Seyreltilmiş Hisse Başı Kâr $0.61$0.62$0.45$0.00$-0.72
Bilanço
2025-12-312024-12-312023-12-312022-12-312021-12-31
Borç / Öz Sermaye 0.20.71.94.5-39.7
Cari Oran 2.01.51.61.71.3
Cari Oran 1.91.41.41.61.0
Nakit Akışı
2025-12-312024-12-312023-12-312022-12-312021-12-31
Serbest Nakit Akışı $42M$39M$27M$-16M$21M

Metriklerim Kişisel izleme listeniz — Tam Temeller'den seçilen satırlar

📊

Sizin için önemli olan metrikleri seçin — yukarıdaki Tam Temeller'deki herhangi bir satırın yanındaki ➕ düğmesine tıklayın.

Seçiminiz kaydedildi ve tüm hisse senetlerinde sizinle birlikte gelir.

Kurumsal Sahipler (13F) 173 dosya · $239.8M toplam · Tarih itibarıyla 30 Haziran 2026

Çeyreklik SEC Form 13F'lerinde bu hisse senedini tuttuklarını bildiren kurumlar. Yalnızca uzun pozisyonlar; tek bir başvuru sahibi, ayrı opsiyon bacakları için iki kez görünebilir. Büyük dengeleyici alım/satım bacakları genellikle piyasa yapımını veya korunmuş envanteri yansıtır, yönlü bir inancı değil.

Kurumsal faaliyet — Q2 2026 ve önceki çeyrek
Yeni pozisyonlar Çıkan pozisyonlar Artırıldı Azaldı Net hisse senedi değişimi
28 (+2 önceki Ç'ye göre) 15 (-2 önceki Ç'ye göre) 56 (+1 önceki Ç'ye göre) 47 (+7 önceki Ç'ye göre) +4.1M

Q1 2026 ile karşılaştırıldı. SEC Form 13F başvuruları, çeyrek sonundan itibaren 45 gün içinde ve geç başvuranlar için kısa bir ek süre içinde tamamlanmalıdır — bu pencere içindeki çeyrekler, en son tam olarak raporlanan çifte tercih edilerek atlanır.

Kurum Değer Hisse senetleri % izlenen 13F'nin Tür
ACORN CAPITAL ADVISORS, LLC $33.504.835 4.131.299 13,97% Hisse senetleri
VANGUARD GROUP INC $21.011.306 3.531.312 8,76% Hisse senetleri
AMERICAN CENTURY COMPANIES INC $18.815.168 2.319.996 7,85% Hisse senetleri
RENAISSANCE TECHNOLOGIES LLC $14.891.687 1.836.213 6,21% Hisse senetleri
VANGUARD CAPITAL MANAGEMENT LLC $14.887.065 1.835.643 6,21% Hisse senetleri
VANGUARD PORTFOLIO MANAGEMENT LLC $14.805.608 1.825.599 6,18% Hisse senetleri
DIMENSIONAL FUND ADVISORS LP $11.407.283 1.406.570 4,76% Hisse senetleri
GEODE CAPITAL MANAGEMENT, LLC $9.618.136 1.185.702 4,01% Hisse senetleri
O'SHAUGHNESSY ASSET MANAGEMENT, LLC $9.113.880 1.123.783 3,80% Hisse senetleri
STATE STREET CORP $7.722.058 952.165 3,22% Hisse senetleri
KENNEDY CAPITAL MANAGEMENT LLC $7.082.082 873.253 2,95% Hisse senetleri
BRIDGEWAY CAPITAL MANAGEMENT, LLC $6.420.006 791.616 2,68% Hisse senetleri
RITHOLTZ WEALTH MANAGEMENT $6.080.862 749.798 2,54% Hisse senetleri
Connor, Clark & Lunn Investment Management Ltd. $5.214.292 642.946 2,17% Hisse senetleri
MILLENNIUM MANAGEMENT LLC $4.884.166 602.240 2,04% Hisse senetleri
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $4.318.170 532.450 1,80% Hisse senetleri
GLOBEFLEX CAPITAL L P $3.104.565 382.807 1,29% Hisse senetleri
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $2.506.850 309.106 1,05% Hisse senetleri
D. E. Shaw & Co., Inc. $2.300.377 283.647 0,96% Hisse senetleri
Russell Investments Group, Ltd. $2.207.323 272.173 0,92% Hisse senetleri
VANGUARD FIDUCIARY TRUST CO $2.182.158 269.070 0,91% Hisse senetleri
FEDERATED HERMES, INC. $2.033.712 250.766 0,85% Hisse senetleri
Empowered Funds, LLC $1.786.763 220.316 0,75% Hisse senetleri
PANAGORA ASSET MANAGEMENT INC $1.764.290 217.545 0,74% Hisse senetleri
GOLDMAN SACHS GROUP INC $1.758.256 216.801 0,73% Hisse senetleri
FMR LLC $1.708.274 210.638 0,71% Hisse senetleri
PRUDENTIAL FINANCIAL INC $1.600.095 197.299 0,67% Hisse senetleri
STATE OF WISCONSIN INVESTMENT BOARD $1.526.562 188.232 0,64% Hisse senetleri
Prospera Financial Services Inc $1.287.530 158.762 0,54% Hisse senetleri
Haven Private, LLC $1.203.913 148.448 0,50% Hisse senetleri
TWO SIGMA INVESTMENTS, LP $1.140.161 140.587 0,48% Hisse senetleri
BlackRock, Inc. $1.134.784 139.924 0,47% Hisse senetleri
FIRST TRUST ADVISORS LP $1.055.970 130.206 0,44% Hisse senetleri
Bank of New York Mellon Corp $1.048.964 129.342 0,44% Hisse senetleri
Round Rock Advisors LLC $1.045.476 128.912 0,44% Hisse senetleri
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $1.040.051 128.243 0,43% Hisse senetleri
STRS OHIO $686.106 84.600 0,29% Hisse senetleri
CANADA PENSION PLAN INVESTMENT BOARD $596.085 73.500 0,25% Hisse senetleri
Trexquant Investment LP $585.729 72.223 0,24% Hisse senetleri
Vise Technologies, Inc. $584.163 72.030 0,24% Hisse senetleri
SUSQUEHANNA INTERNATIONAL GROUP, LLP $520.662 64.200 0,22% Alım opsiyonu
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $497.000 61.255 0,21% Hisse senetleri
OpenArc Corporate Advisory, LLC $482.472 59.491 0,20% Hisse senetleri
RHUMBLINE ADVISERS $466.397 57.510 0,19% Hisse senetleri
TWO SIGMA ADVISERS, LP $423.045 71.100 0,18% Hisse senetleri
D'Orazio & Associates, Inc. $394.795 48.680 0,16% Hisse senetleri
Vanguard Global Advisers, LLC $375.225 46.267 0,16% Hisse senetleri
DEUTSCHE BANK AG\ $350.287 43.192 0,15% Hisse senetleri
Man Group plc $336.614 41.506 0,14% Hisse senetleri
WELLINGTON MANAGEMENT GROUP LLP $333.240 41.090 0,14% Hisse senetleri
WINTON GROUP Ltd $328.528 40.509 0,14% Hisse senetleri
XTX Topco Ltd $326.801 40.296 0,14% Hisse senetleri
State of Wyoming $323.046 39.833 0,13% Hisse senetleri
WELLS FARGO & COMPANY/MN $304.977 37.605 0,13% Hisse senetleri
EntryPoint Capital, LLC $303.200 37.386 0,13% Hisse senetleri
Baron Wealth Management LLC $294.977 36.372 0,12% Hisse senetleri
Creative Planning $289.827 35.737 0,12% Hisse senetleri
LPL Financial LLC $280.095 34.537 0,12% Hisse senetleri
Universal- Beteiligungs- und Servicegesellschaft mbH $279.673 34.485 0,12% Hisse senetleri
BANK OF AMERICA CORP /DE/ $257.468 31.747 0,11% Hisse senetleri
Kathmere Capital Management, LLC $252.805 31.172 0,11% Hisse senetleri
FRANKLIN RESOURCES INC $242.165 29.860 0,10% Hisse senetleri
ENVESTNET ASSET MANAGEMENT INC $236.731 29.190 0,10% Hisse senetleri
Y-Intercept (Hong Kong) Ltd $212.660 26.222 0,09% Hisse senetleri
MARTINGALE ASSET MANAGEMENT L P $205.703 25.364 0,09% Hisse senetleri
Metis Global Partners, LLC $204.891 25.264 0,09% Hisse senetleri
MetLife Investment Management, LLC $201.720 24.873 0,08% Hisse senetleri
SUSQUEHANNA INTERNATIONAL GROUP, LLP $195.451 24.100 0,08% Satım opsiyonu
C2C Wealth Management, LLC $191.558 23.620 0,08% Hisse senetleri
Nuveen, LLC $187.982 23.179 0,08% Hisse senetleri
PRELUDE CAPITAL MANAGEMENT, LLC $174.754 21.548 0,07% Hisse senetleri
One Wealth Advisors, LLC $170.951 21.079 0,07% Hisse senetleri
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $165.306 20.383 0,07% Hisse senetleri
CITIGROUP INC $154.990 19.111 0,06% Hisse senetleri
BAILARD, INC. $146.791 18.100 0,06% Hisse senetleri
Invesco Ltd. $142.493 17.570 0,06% Hisse senetleri
JANE STREET GROUP, LLC $141.925 17.500 0,06% Alım opsiyonu
Spark Investment Management LLC $137.870 17.000 0,06% Hisse senetleri
MORGAN STANLEY $137.416 16.944 0,06% Hisse senetleri
ALLIANCEBERNSTEIN L.P. $136.490 21.360 0,06% Hisse senetleri
Brandywine Global Investment Management, LLC $129.710 21.800 0,05% Hisse senetleri
Police & Firemen's Retirement System of New Jersey $127.481 15.719 0,05% Hisse senetleri
SUSQUEHANNA INTERNATIONAL GROUP, LLP $125.510 15.476 0,05% Hisse senetleri
Lido Advisors, LLC $122.015 15.045 0,05% Hisse senetleri
Mariner, LLC $120.593 14.869 0,05% Hisse senetleri
Caprock Group, LLC $112.421 13.862 0,05% Hisse senetleri
PERKINS CAPITAL MANAGEMENT INC $108.674 13.400 0,05% Hisse senetleri
TOCQUEVILLE ASSET MANAGEMENT L.P. $107.960 13.312 0,05% Hisse senetleri
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $105.624 13.203 0,04% Hisse senetleri
UBS Group AG $99.923 12.321 0,04% Hisse senetleri
MANUFACTURERS LIFE INSURANCE COMPANY, THE $97.774 12.056 0,04% Hisse senetleri
CWM, LLC $97.531 15.263 0,04% Hisse senetleri
R Squared Ltd $97.247 11.991 0,04% Hisse senetleri
Abel Hall, LLC $93.427 11.520 0,04% Hisse senetleri
IEQ CAPITAL, LLC $86.542 10.671 0,04% Hisse senetleri
Williams & Novak, LLC $85.066 10.489 0,04% Hisse senetleri
Vanguard Personalized Indexing Management, LLC $84.409 10.408 0,04% Hisse senetleri
Ethic Inc. $83.290 10.270 0,03% Hisse senetleri
AQR CAPITAL MANAGEMENT LLC $83.136 10.251 0,03% Hisse senetleri
INTECH INVESTMENT MANAGEMENT LLC $82.803 10.210 0,03% Hisse senetleri

Şirket yöneticileri 24 içeriden öğrenenler · 10 yöneticiler · 12 yönetim kurulu üyeleri

İçeriden Öğrenen Rol Son işlem Sahip olunan hisse senetleri Alımlar 12ay Satışlar 12ay Net 12ay
Alan H Auerbach President and CEO 06 Temmuz 2026 S 7.261.671 0 1 $-363.919
Maximo F Nougues Chief Financial Officer 06 Temmuz 2026 S 230.637 0 1 $-77.528
Douglas M Hunt The Reporting Person is the Senior Vice President of Regulatory Affairs of the Issuer. 06 Temmuz 2026 S 196.841 0 1 $-69.880
Alvin F Wong Chief Scientific Officer 17 Haziran 2021 A 0 0 $0
Richard Paul Bryce Title of Reporting Person: Chief Medical and Scientific Officer 05 Nisan 2021 S 121.662 0 0 $0
Jeffrey Jerome Ludwig Chief Commercial Officer 17 Şubat 2021 A 36.069 0 0 $0
Steven Lo Chief Commercial Officer 22 Temmuz 2019 S 19.557 0 0 $0
Charles R Eyler Title of Reporting Person: Senior Vice President, Finance and Administration and Treasurer 04 Şubat 2019 S 31.957 0 0 $0
Robert Charnas The Reporting Person is the Senior Vice President of Regulatory Affairs and Project Management of the Issuer. 16 Şubat 2017 A 26.453 0 0 $0
Richard Benton Phillips The Reporting Person is the Interim Head of Regulatory Affairs, Quality Assurance and Pharmacovigilance of the Issuer. 15 Nisan 2016 A 0 0 $0
Brian M Stuglik Yönetim kurulu üyesi 12 Haziran 2026 S 113.858 0 1 $-58.320
Allison Dorval Yönetim kurulu üyesi 12 Haziran 2026 S 90.780 0 1 $-83.592
Adrian Senderowicz Yönetim kurulu üyesi 12 Haziran 2026 S 27.000 0 1 $-194.400
Troy Edward Wilson Yönetim kurulu üyesi 12 Haziran 2026 S 59.750 0 1 $-77.760
Jay M Moyes Yönetim kurulu üyesi 12 Haziran 2026 S 58.322 0 1 $-158.840
Alessandra Cesano Yönetim kurulu üyesi 11 Haziran 2026 A 68.850 0 0 $0
MILLER MICHAEL PATRICK Yönetim kurulu üyesi 11 Haziran 2026 A 81.000 0 0 $0
Ann Calby Miller Yönetim kurulu üyesi 15 Haziran 2021 A 40.732 0 0 $0
Hugh O'Dowd Yönetim kurulu üyesi 09 Haziran 2020 A 25.748 0 0 $0
Frank Zavrl Yönetim kurulu üyesi 09 Haziran 2020 A 50.993 0 0 $0
Thomas Malley Yönetim kurulu üyesi 15 Aralık 2014 A 156.551 0 0 $0
Faraaz Siddiqi 04 Ekim 2011 D 0 0 0 $0
Kapil Munjal 04 Ekim 2011 D 0 0 0 $0
Robert Andrew Johnson 04 Ekim 2011 D 0 0 0 $0

SEC Form 3/4/5 başvurularından yöneticiler; net = yalnızca açık piyasa Alış/Satış

Aktivistler ve %5+ sahipler 7 pozisyon

SEC Çizelge 13D dosyalayan yatırımcılar — ihraççı üzerinde nüfuz etme niyetiyle %5'in üzerinde faydalı sahiplik (aktivist hisseler, yönetim kurulu kampanyaları, M&A). Her satır, o başvuru sahibinin pozisyonunun bilinen en son durumunu gösterir.

Başvuru sahibi Dosyalandı Hisse Durum Amaç Başvuru
Alan H. Auerbach ×6 başvurular 13 Aralık 2022 İlk başvuru SEC
Kapil Munjal 2) 04 Ekim 2011 İlk başvuru SEC
Faraaz Siddiqi 2) 04 Ekim 2011 İlk başvuru SEC
Robert Johnson 2) 04 Ekim 2011 İlk başvuru SEC
Robert Johnson 21 Kasım 2007 İlk başvuru SEC
Açıklanmayan raporlama kişisi 19 Kasım 2007 İlk başvuru SEC
Faraaz Siddiqi 19 Kasım 2007 İlk başvuru SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF sahipliği 36 ETF'ler tarafından tutuluyor

Ağırlık yalnızca doğrudan öz sermaye varlıklarını (N-PORT) yansıtır; kaldıraçlı veya türev tabanlı fonlar gösterilmeyen ek swap pozisyonlarına sahip olabilir.

Fon Ağırlık Birimler Tarih itibarıyla Kaynak
ROSC · Lattice Strategies Trust 0,72% 52.608 NS 30 Nisan 2026 N-PORT
DWAS · Invesco Exchange-Traded Fund Trust … 0,46% 233.908 SH 08 Ağustos 2026 Günlük
IWC · iShares Trust 0,08% 150.797 SH 08 Ağustos 2026 Günlük
VFQY · VANGUARD WELLINGTON FUND 0,06% 34.260 SH 08 Ağustos 2026 Günlük
AVUV · AMERICAN CENTURY ETF TRUST 0,05% 1.924.360 NS 31 Mayıs 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0,04% 55.680 NS 31 Mayıs 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0,03% 2.746 SH 08 Ağustos 2026 Günlük
AVSC · AMERICAN CENTURY ETF TRUST 0,02% 95.559 NS 31 Mayıs 2026 N-PORT
VTWV · VANGUARD SCOTTSDALE FUNDS 0,02% 32.358 SH 08 Ağustos 2026 Günlük
IWN · iShares Trust 0,02% 356.623 SH 08 Ağustos 2026 Günlük
BIB · ProShares Trust 0,02% 1.879 NS 31 Mayıs 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,02% 55.064 SH 08 Ağustos 2026 Günlük
IWM · iShares Trust 0,01% 1.153.241 SH 08 Ağustos 2026 Günlük
RSSL · Global X Funds 0,01% 19.123 NS 30 Nisan 2026 N-PORT
VFMO · VANGUARD WELLINGTON FUND 0,01% 16.014 SH 08 Ağustos 2026 Günlük
VTWO · VANGUARD SCOTTSDALE FUNDS 0,01% 254.380 SH 08 Ağustos 2026 Günlük
DFAS · Dimensional ETF Trust 0,01% 166.672 NS 30 Nisan 2026 N-PORT
DFAT · Dimensional ETF Trust 0,01% 156.761 NS 30 Nisan 2026 N-PORT
DFSV · Dimensional ETF Trust 0,01% 82.003 NS 30 Nisan 2026 N-PORT
ITWO · ProShares Trust 0,01% 2.027 NS 31 Mayıs 2026 N-PORT
DXUV · Dimensional ETF Trust 0,01% 3.611 NS 30 Nisan 2026 N-PORT
EBI · RBB Fund Trust 0,01% 5.394 NS 31 Mayıs 2026 N-PORT
UWM · ProShares Trust 0,00% 1.585 NS 31 Mayıs 2026 N-PORT
IWO · iShares Trust 0,00% 65.370 SH 08 Ağustos 2026 Günlük
URTY · ProShares Trust 0,00% 1.603 NS 31 Mayıs 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,00% 2.071 NS 31 Mayıs 2026 N-PORT
AVUS · AMERICAN CENTURY ETF TRUST 0,00% 34.919 NS 31 Mayıs 2026 N-PORT
DCOR · Dimensional ETF Trust 0,00% 6.348 NS 30 Nisan 2026 N-PORT
HDG · ProShares Trust 0,00% 40 NS 31 Mayıs 2026 N-PORT
DFAU · Dimensional ETF Trust 0,00% 9.704 NS 30 Nisan 2026 N-PORT
DFUS · Dimensional ETF Trust 0,00% 15.090 NS 30 Nisan 2026 N-PORT
DFAC · Dimensional ETF Trust 0,00% 12.376 NS 30 Nisan 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0,00% 446.899 SH 08 Ağustos 2026 Günlük
VTI · VANGUARD INDEX FUNDS 0,00% 1.343.121 SH 08 Ağustos 2026 Günlük
VTWG · VANGUARD SCOTTSDALE FUNDS 0,00% 7.680 SH 08 Ağustos 2026 Günlük
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 2.979 SH 08 Ağustos 2026 Günlük