IRON — Institutionelle Eigentümer (13F)
Institutionen, die diese Aktie in ihrer vierteljährlichen SEC-Formular 13F melden. Nur Long-Positionen; ein einzelner Einreicher kann für separate Optionsscheine zweimal erscheinen. Große gegenläufige Put/Call-Positionen spiegeln typischerweise Market-Making oder abgesicherte Bestände wider, nicht die gerichtete Überzeugung.
| Institution | Wert | Aktien | % der verfolgten 13F | Typ |
|---|---|---|---|---|
| FMR LLC | $357.981.753 | 4.894.473 | 11,37% | Aktien |
| BlackRock, Inc. | $180.502.133 | 2.467.899 | 5,73% | Aktien |
| RA CAPITAL MANAGEMENT, L.P. | $179.209.164 | 2.450.221 | 5,69% | Aktien |
| VANGUARD GROUP INC | $140.371.470 | 1.767.680 | 4,46% | Aktien |
| JPMORGAN CHASE & CO | $139.868.053 | 1.875.795 | 4,44% | Aktien |
| WELLINGTON MANAGEMENT GROUP LLP | $127.362.413 | 1.741.351 | 4,05% | Aktien |
| STATE STREET CORP | $120.595.865 | 1.648.836 | 3,83% | Aktien |
| Vestal Point Capital, LP | $113.367.000 | 1.550.000 | 3,60% | Aktien |
| Atlas Venture Life Science Advisors, LLC | $110.724.818 | 1.513.875 | 3,52% | Aktien |
| VANGUARD CAPITAL MANAGEMENT LLC | $100.130.635 | 1.369.027 | 3,18% | Aktien |
| Frazier Life Sciences Management, L.P. | $99.093.875 | 1.354.852 | 3,15% | Aktien |
| TCG Crossover Management, LLC | $98.143.787 | 1.341.862 | 3,12% | Aktien |
| BVF INC/IL | $84.375.182 | 1.153.612 | 2,68% | Aktien |
| Woodline Partners LP | $70.088.672 | 958.281 | 2,23% | Aktien |
| Siren, L.L.C. | $64.977.649 | 888.401 | 2,06% | Aktien |
| Logos Global Management LP | $63.997.500 | 875.000 | 2,03% | Aktien |
| Opaleye Management Inc. | $62.534.700 | 855.000 | 1,99% | Aktien |
| GEODE CAPITAL MANAGEMENT, LLC | $57.772.342 | 789.724 | 1,84% | Aktien |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $48.052.980 | 657.000 | 1,53% | Aktien |
| DIMENSIONAL FUND ADVISORS LP | $41.622.451 | 569.018 | 1,32% | Aktien |
| Bellevue Group AG | $40.958.400 | 560.000 | 1,30% | Aktien |
| Saturn V Capital Management LP | $38.378.752 | 524.730 | 1,22% | Aktien |
| ARMISTICE CAPITAL, LLC | $33.644.400 | 460.000 | 1,07% | Aktien |
| JENNISON ASSOCIATES LLC | $32.146.492 | 439.520 | 1,02% | Aktien |
| Aberdeen Group plc | $32.048.046 | 438.174 | 1,02% | Aktien |
| Palo Alto Investors LP | $30.473.488 | 416.646 | 0,97% | Aktien |
| EVENTIDE ASSET MANAGEMENT, LLC | $28.938.480 | 395.651 | 0,92% | Aktien |
| Pictet Asset Management Holding SA | $28.186.328 | 385.375 | 0,90% | Aktien |
| Assenagon Asset Management S.A. | $28.097.316 | 384.158 | 0,89% | Aktien |
| LOOMIS SAYLES & CO L P | $27.929.533 | 381.864 | 0,89% | Aktien |
| Foresite Capital Management V, LLC | $27.359.407 | 374.069 | 0,87% | Aktien |
| ORBIMED ADVISORS LLC | $26.150.110 | 357.535 | 0,83% | Aktien |
| BAKER BROS. ADVISORS LP | $25.573.913 | 349.657 | 0,81% | Aktien |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20.620.872 | 281.937 | 0,66% | Aktien |
| Octagon Capital Advisors LP | $19.747.800 | 270.000 | 0,63% | Aktien |
| NORTHERN TRUST CORP | $19.381.368 | 264.990 | 0,62% | Aktien |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $18.824.919 | 257.382 | 0,60% | Aktien |
| Checkpoint Capital L.P. | $17.562.743 | 240.125 | 0,56% | Aktien |
| VANGUARD FIDUCIARY TRUST CO | $16.470.982 | 225.198 | 0,52% | Aktien |
| CITADEL ADVISORS LLC | $15.308.787 | 209.308 | 0,49% | Aktien |
| Bank of New York Mellon Corp | $14.973.763 | 204.727 | 0,48% | Aktien |
| BNP PARIBAS FINANCIAL MARKETS | $13.508.592 | 184.695 | 0,43% | Aktien |
| Catalio Capital Management, LP | $11.657.346 | 159.384 | 0,37% | Aktien |
| Caption Management, LLC | $10.971.000 | 150.000 | 0,35% | Kaufoption |
| Sofinnova Investments, Inc. | $10.695.920 | 146.239 | 0,34% | Aktien |
| Bain Capital Life Sciences Investors, LLC | $10.329.855 | 141.234 | 0,33% | Aktien |
| TWO SIGMA INVESTMENTS, LP | $10.001.895 | 136.750 | 0,32% | Aktien |
| BANK OF AMERICA CORP /DE/ | $9.882.018 | 135.111 | 0,31% | Aktien |
| Alyeska Investment Group, L.P. | $9.142.500 | 125.000 | 0,29% | Aktien |
| Ensign Peak Advisors, Inc | $8.931.199 | 122.111 | 0,28% | Aktien |
| UBS Group AG | $8.116.419 | 110.971 | 0,26% | Aktien |
| Trexquant Investment LP | $7.877.105 | 107.699 | 0,25% | Aktien |
| KENNEDY CAPITAL MANAGEMENT LLC | $7.809.085 | 106.769 | 0,25% | Aktien |
| MILLENNIUM MANAGEMENT LLC | $7.770.979 | 106.248 | 0,25% | Aktien |
| GOLDMAN SACHS GROUP INC | $7.122.593 | 97.383 | 0,23% | Aktien |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $7.090.307 | 110.890 | 0,23% | Aktien |
| MORGAN STANLEY | $6.699.315 | 91.595 | 0,21% | Aktien |
| SILVERARC CAPITAL MANAGEMENT, LLC | $6.055.992 | 82.800 | 0,19% | Aktien |
| RAYMOND JAMES FINANCIAL INC | $5.703.384 | 77.980 | 0,18% | Aktien |
| Squarepoint Ops LLC | $5.549.278 | 75.872 | 0,18% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5.383.104 | 73.600 | 0,17% | Kaufoption |
| DNB Asset Management AS | $5.348.509 | 73.127 | 0,17% | Aktien |
| Casdin Capital, LLC | $4.754.100 | 65.000 | 0,15% | Aktien |
| SPHERA FUNDS MANAGEMENT LTD. | $4.647.169 | 63.538 | 0,15% | Aktien |
| Nuveen, LLC | $4.414.511 | 60.357 | 0,14% | Aktien |
| PEAK6 LLC | $4.388.400 | 60.000 | 0,14% | Kaufoption |
| KVP Capital Advisors, LP | $4.260.405 | 58.250 | 0,14% | Aktien |
| MOORE CAPITAL MANAGEMENT, LP | $4.227.199 | 57.796 | 0,13% | Aktien |
| XTX Topco Ltd | $4.147.769 | 56.710 | 0,13% | Aktien |
| NEXTBio Capital Management LP | $3.851.187 | 52.655 | 0,12% | Aktien |
| ALGERT GLOBAL LLC | $3.792.309 | 51.850 | 0,12% | Aktien |
| ExodusPoint Capital Management, LP | $3.775.706 | 51.623 | 0,12% | Aktien |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $3.725.000 | 50.000 | 0,12% | Aktien |
| Burkehill Global Management, LP | $3.657.000 | 50.000 | 0,12% | Aktien |
| Brevan Howard Capital Management LP | $3.656.707 | 49.996 | 0,12% | Aktien |
| Swiss National Bank | $3.642.372 | 49.800 | 0,12% | Aktien |
| AMERIPRISE FINANCIAL INC | $3.355.224 | 45.874 | 0,11% | Aktien |
| Atle Fund Management AB | $3.194.901 | 43.682 | 0,10% | Aktien |
| Quadrature Capital Ltd | $3.102.526 | 42.419 | 0,10% | Aktien |
| Invesco Ltd. | $3.076.049 | 42.057 | 0,10% | Aktien |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.878.790 | 39.360 | 0,09% | Aktien |
| ALPS ADVISORS INC | $2.820.644 | 38.565 | 0,09% | Aktien |
| CITIGROUP INC | $2.802.506 | 38.317 | 0,09% | Aktien |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $2.798.483 | 38.262 | 0,09% | Aktien |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $2.679.411 | 36.634 | 0,09% | Aktien |
| RHUMBLINE ADVISERS | $2.621.620 | 35.844 | 0,08% | Aktien |
| LAZARD ASSET MANAGEMENT LLC | $2.562.387 | 35.034 | 0,08% | Aktien |
| SEVEN GRAND MANAGERS, LLC | $2.559.900 | 35.000 | 0,08% | Aktien |
| MARSHALL WACE, LLP | $2.515.577 | 34.394 | 0,08% | Aktien |
| Jump Financial, LLC | $2.380.634 | 32.549 | 0,08% | Aktien |
| BANK OF MONTREAL /CAN/ | $2.363.007 | 32.308 | 0,08% | Aktien |
| DEUTSCHE BANK AG\ | $2.241.229 | 30.643 | 0,07% | Aktien |
| ALLIANCEBERNSTEIN L.P. | $2.216.800 | 34.670 | 0,07% | Aktien |
| RTW INVESTMENTS, LP | $2.194.200 | 30.000 | 0,07% | Aktien |
| Squadron Capital Management LLC | $2.194.200 | 30.000 | 0,07% | Kaufoption |
| VICTORY CAPITAL MANAGEMENT INC | $2.129.618 | 29.117 | 0,07% | Aktien |
| WELLS FARGO & COMPANY/MN | $2.115.464 | 28.924 | 0,07% | Aktien |
| TUDOR INVESTMENT CORP ET AL | $2.096.412 | 28.663 | 0,07% | Aktien |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2.031.171 | 27.771 | 0,06% | Aktien |
| Y-Intercept (Hong Kong) Ltd | $1.966.588 | 26.888 | 0,06% | Aktien |
| Rafferty Asset Management, LLC | $1.943.037 | 26.566 | 0,06% | Aktien |
| Campbell & CO Investment Adviser LLC | $1.870.044 | 25.568 | 0,06% | Aktien |
| PNC Financial Services Group, Inc. | $1.633.435 | 22.333 | 0,05% | Aktien |
| TD Asset Management Inc | $1.579.824 | 21.600 | 0,05% | Aktien |
| Engineers Gate Manager LP | $1.430.033 | 19.552 | 0,05% | Aktien |
| BARCLAYS PLC | $1.368.450 | 18.710 | 0,04% | Aktien |
| Legal & General Group Plc | $1.350.019 | 18.458 | 0,04% | Aktien |
| DLD Asset Management, LP | $1.330.238 | 18.200 | 0,04% | Verkaufsoption |
| CITADEL ADVISORS LLC | $1.258.008 | 17.200 | 0,04% | Verkaufsoption |
| MetLife Investment Management, LLC | $1.213.246 | 16.588 | 0,04% | Aktien |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1.182.775 | 16.114 | 0,04% | Aktien |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.178.359 | 16.111 | 0,04% | Aktien |
| JANE STREET GROUP, LLC | $1.171.045 | 16.011 | 0,04% | Aktien |
| CITADEL ADVISORS LLC | $1.155.612 | 15.800 | 0,04% | Kaufoption |
| STATE OF WISCONSIN INVESTMENT BOARD | $1.128.477 | 15.429 | 0,04% | Aktien |
| Man Group plc | $1.091.615 | 14.925 | 0,03% | Aktien |
| HighVista Strategies LLC | $1.039.978 | 14.219 | 0,03% | Aktien |
| PROFUND ADVISORS LLC | $988.048 | 13.509 | 0,03% | Aktien |
| Ikarian Capital, LLC | $972.762 | 13.300 | 0,03% | Kaufoption |
| Ikarian Capital, LLC | $972.762 | 13.300 | 0,03% | Verkaufsoption |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $948.699 | 12.971 | 0,03% | Aktien |
| Qube Research & Technologies Ltd | $933.120 | 12.758 | 0,03% | Aktien |
| SEI INVESTMENTS CO | $925.008 | 12.647 | 0,03% | Aktien |
| MARTINGALE ASSET MANAGEMENT L P | $878.339 | 12.009 | 0,03% | Aktien |
| Vanguard Global Advisers, LLC | $848.205 | 11.597 | 0,03% | Aktien |
| JANUS HENDERSON GROUP PLC | $739.462 | 11.555 | 0,02% | Aktien |
| NEW YORK STATE COMMON RETIREMENT FUND | $736.959 | 10.076 | 0,02% | Aktien |
| AQR CAPITAL MANAGEMENT LLC | $721.745 | 9.868 | 0,02% | Aktien |
| JANE STREET GROUP, LLC | $665.574 | 9.100 | 0,02% | Kaufoption |
| Entropy Technologies, LP | $614.961 | 8.408 | 0,02% | Aktien |
| Police & Firemen's Retirement System of New Jersey | $610.353 | 8.345 | 0,02% | Aktien |
| China Universal Asset Management Co., Ltd. | $602.600 | 8.239 | 0,02% | Aktien |
| Lion Point Capital, LP | $592.434 | 8.100 | 0,02% | Aktien |
| Russell Investments Group, Ltd. | $591.190 | 8.083 | 0,02% | Aktien |
| State of New Jersey Common Pension Fund D | $586.583 | 8.020 | 0,02% | Aktien |
| PSP Research LLC | $585.120 | 8.000 | 0,02% | Aktien |
| Cubist Systematic Strategies, LLC | $575.848 | 8.714 | 0,02% | Aktien |
| Quantinno Capital Management LP | $533.703 | 7.297 | 0,02% | Aktien |
| JANE STREET GROUP, LLC | $526.608 | 7.200 | 0,02% | Verkaufsoption |
| ARIZONA STATE RETIREMENT SYSTEM | $500.570 | 6.844 | 0,02% | Aktien |
| EntryPoint Capital, LLC | $465.975 | 6.371 | 0,01% | Aktien |
| SummitTX Capital, L.P. | $461.440 | 6.309 | 0,01% | Aktien |
| Creative Planning | $457.418 | 6.254 | 0,01% | Aktien |
| INTECH INVESTMENT MANAGEMENT LLC | $442.790 | 6.054 | 0,01% | Aktien |
| AXQ CAPITAL, LP | $441.400 | 6.035 | 0,01% | Aktien |
| D. E. Shaw & Co., Inc. | $440.815 | 6.027 | 0,01% | Aktien |
| Vanguard Investments Australia, Ltd. | $435.841 | 5.959 | 0,01% | Aktien |
| Susquehanna Portfolio Strategies, LLC | $424.797 | 5.808 | 0,01% | Aktien |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $412.510 | 5.640 | 0,01% | Aktien |
| VOYA INVESTMENT MANAGEMENT LLC | $397.150 | 5.430 | 0,01% | Aktien |
| KLP KAPITALFORVALTNING AS | $380.328 | 5.200 | 0,01% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $365.700 | 5.000 | 0,01% | Verkaufsoption |
| ProShare Advisors LLC | $362.701 | 4.959 | 0,01% | Aktien |
| Virtus Investment Advisers, LLC | $351.950 | 4.812 | 0,01% | Aktien |
| JONES FINANCIAL COMPANIES LLLP | $345.184 | 4.616 | 0,01% | Aktien |
| PRUDENTIAL FINANCIAL INC | $338.638 | 4.630 | 0,01% | Aktien |
| Eleva Capital SAS | $327.053 | 5.115 | 0,01% | Aktien |
| Fiduciary Trust Co | $296.290 | 4.051 | 0,01% | Aktien |
| AlphaCentric Advisors LLC | $294.754 | 4.030 | 0,01% | Aktien |
| BOOTHBAY FUND MANAGEMENT, LLC | $292.560 | 4.000 | 0,01% | Kaufoption |
| BOOTHBAY FUND MANAGEMENT, LLC | $292.560 | 4.000 | 0,01% | Verkaufsoption |
| E Fund Management Co., Ltd. | $273.982 | 3.746 | 0,01% | Aktien |
| Bryce Point Capital, LLC | $258.505 | 3.912 | 0,01% | Aktien |
| CAPSTONE INVESTMENT ADVISORS, LLC | $245.385 | 3.355 | 0,01% | Aktien |
| Jain Global LLC | $228.928 | 3.130 | 0,01% | Aktien |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $225.417 | 3.082 | 0,01% | Aktien |
| DLD Asset Management, LP | $219.420 | 3.000 | 0,01% | Aktien |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $213.130 | 2.914 | 0,01% | Aktien |
| TEACHER RETIREMENT SYSTEM OF TEXAS | $211.741 | 2.895 | 0,01% | Aktien |
| STRS OHIO | $197.478 | 2.700 | 0,01% | Aktien |
| Ameritas Investment Partners, Inc. | $187.824 | 2.568 | 0,01% | Aktien |
| Quantbot Technologies LP | $152.863 | 2.090 | 0,00% | Aktien |
| PRICE T ROWE ASSOCIATES INC /MD/ | $137.168 | 1.875.399 | 0,00% | Aktien |
| Mirae Asset Global Investments Co., Ltd. | $124.923 | 1.708 | 0,00% | Aktien |
| US BANCORP \DE\ | $89.889 | 1.229 | 0,00% | Aktien |
| ROYAL BANK OF CANADA | $73.000 | 989 | 0,00% | Aktien |
| Foresite Capital Management VI LLC | $70.946 | 970 | 0,00% | Aktien |
| Tower Research Capital LLC (TRC) | $68.678 | 939 | 0,00% | Aktien |
| CWM, LLC | $66.178 | 1.035 | 0,00% | Aktien |
| GF FUND MANAGEMENT CO. LTD. | $59.170 | 809 | 0,00% | Aktien |
| Allworth Financial LP | $46.298 | 633 | 0,00% | Aktien |
| NISA INVESTMENT ADVISORS, LLC | $41.397 | 566 | 0,00% | Aktien |
| Steward Partners Investment Advisory, LLC | $38.618 | 528 | 0,00% | Aktien |
| Bayforest Capital Ltd | $32.986 | 451 | 0,00% | Aktien |
| AlphaQuest LLC | $29.064 | 366 | 0,00% | Aktien |
| State of Wyoming | $25.306 | 346 | 0,00% | Aktien |
| GAMMA Investing LLC | $21.357 | 292 | 0,00% | Aktien |
| Kemnay Advisory Services Inc. | $19.675 | 269 | 0,00% | Aktien |
| OSAIC HOLDINGS, INC. | $19.602 | 268 | 0,00% | Aktien |
| TORONTO DOMINION BANK | $14.482 | 198 | 0,00% | Aktien |
| J.Safra Asset Management Corp | $11.776 | 161 | 0,00% | Aktien |
| Larson Financial Group LLC | $8.996 | 123 | 0,00% | Aktien |
| Sterling Capital Management LLC | $7.241 | 99 | 0,00% | Aktien |
| Smartleaf Asset Management LLC | $6.854 | 92 | 0,00% | Aktien |
| HRT FINANCIAL LP | $6.642 | 90.822 | 0,00% | Aktien |
| Arax Advisory Partners | $6.290 | 86 | 0,00% | Aktien |
| CoreCap Advisors, LLC | $5.705 | 78 | 0,00% | Aktien |
| iA Global Asset Management Inc. | $4.829 | 66.023 | 0,00% | Aktien |
| Optiver Holding B.V. | $4.754 | 65 | 0,00% | Aktien |
| Farther Finance Advisors, LLC | $3.439 | 47 | 0,00% | Aktien |
| Versant Capital Management, Inc | $3.273 | 50 | 0,00% | Aktien |
| Lindbrook Capital, LLC | $2.879 | 58 | 0,00% | Aktien |
| FIRST HORIZON CORP | $2.633 | 36 | 0,00% | Aktien |
| ROTHSCHILD INVESTMENT LLC | $2.340 | 32 | 0,00% | Aktien |
| Silver Grove Financial Group, Inc. | $1.902 | 26 | 0,00% | Aktien |
| FIFTH THIRD BANCORP | $1.844 | 25 | 0,00% | Aktien |
| COMERICA BANK | $1.544 | 19 | 0,00% | Aktien |
| Parkside Financial Bank & Trust | $1.462 | 20 | 0,00% | Aktien |
| Quarry LP | $1.317 | 18 | 0,00% | Aktien |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | $1.287 | 17.599 | 0,00% | Aktien |
| JPL Wealth Management, LLC | $1.244 | 17 | 0,00% | Aktien |
| EverSource Wealth Advisors, LLC | $1.243 | 17 | 0,00% | Aktien |
| GSA CAPITAL PARTNERS LLP | $1.194 | 16.324 | 0,00% | Aktien |
| Geneos Wealth Management Inc. | $951 | 13 | 0,00% | Aktien |
| HUNTINGTON NATIONAL BANK | $878 | 12 | 0,00% | Aktien |
| ASSETMARK, INC | $878 | 12 | 0,00% | Aktien |
| Cornerstone Financial Management LLC | $805 | 11 | 0,00% | Aktien |
| Bare Financial Services, Inc | $658 | 9 | 0,00% | Aktien |
| SG Americas Securities, LLC | $563 | 7.704 | 0,00% | Aktien |
| Keating Financial Advisory Services, Inc. | $439 | 6 | 0,00% | Aktien |
| Essential Partners LLC | $366 | 5 | 0,00% | Aktien |
| Virtu Financial LLC | $343 | 4.694 | 0,00% | Aktien |
| Global Retirement Partners, LLC | $293 | 4 | 0,00% | Aktien |
| Clearstead Advisors, LLC | $148 | 2 | 0,00% | Aktien |
| Hughes Financial Services, LLC | $146 | 2 | 0,00% | Aktien |
| Downshift Financial, LLC | $146 | 2 | 0,00% | Aktien |
| KBC Group NV | $74 | 1.011 | 0,00% | Aktien |
| Fortitude Family Office, LLC | $73 | 1 | 0,00% | Aktien |
| Wealth Enhancement Trust Services, Inc. | $73 | 1 | 0,00% | Aktien |
| SBI Securities Co., Ltd. | $73 | 1 | 0,00% | Aktien |
| IFP Advisors, Inc | $73 | 1 | 0,00% | Aktien |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | $53 | 730 | 0,00% | Aktien |
| Pacer Advisors, Inc. | $32 | 444 | 0,00% | Aktien |
| Covestor Ltd | $1 | 7 | 0,00% | Aktien |
| GW&K Investment Management, LLC | $1 | 16 | 0,00% | Aktien |