ALNY logo
ALNY NASDAQ US

Alnylam Pharmaceuticals, Inc. - Common Stock

Healthcare · Biotechnology Website · IPO May 2004
$318.85
▼ $-9.88 (-3.01%)
Vol 872K
6
Quality Score
fail
Mkt Cap
$52.5B
P/E
1205.9
ROE
26.1%
Margin
1.4%
D/E
1071.05
Beta
0.32
52W
$206–$496

Wall Street Consensus

36 analysts · Apr 2026
7
Strong Buy
20
Buy
9
Hold
0
Sell
0
Strong Sell
75.0%
Buy Rating

Price Chart

Earnings

Beat rate: 75.0%
Quarter EPS Est EPS Act Surprise
Dec 2025 $1.15 $0.82 $-0.33
Sep 2025 $0.76 $2.11 +$1.35
Jun 2025 $-0.73 $-0.51 +$0.22
Mar 2025 $-1.03 $-0.44 +$0.59

Fundamentals Trend

Metric 2025-06-30 2025-09-02 2025-10-02 2025-11-03 2025-12-03 2026-01-02
ROE (TTM) -274.2% -274.2% -274.2% -274.2% -274.2% 26.1%
P/E (TTM) 1205.90
Net Margin -8.6% -13.0% -13.0% -13.0% -13.0% 1.4%
Gross Margin 81.5% 83.6% 83.6% 83.6% 83.6% 83.9%
D/E Ratio 985.35 409.64 409.64 409.64 409.64 1071.05
Current Ratio 2.80 2.80 2.80 2.80 2.80 2.54

Key Ratios

ROA (TTM)
1.0%
P/S (TTM)
16.37
P/B
452.4
EPS (TTM)
$0.23
CF/Share
$-3.62
Rev Growth 3Y
+38.6%
52W High
$495.55
52W Low
$205.87
$205.87 52-Week Range $495.55

How does ALNY compare to Biotechnology peers?

Peer group: Micro-cap Biotechnology (All) · 528 companies

ALNY AAPG ABEO ABOS ABP

ALNY valuation vs Biotechnology peers

P/E ratio
1205.9
6321% above peers (18.8)
vs Peers
vs Industry
Undervalued
P/S ratio
16.4
27% above peers (12.9)
vs Peers
vs Industry
Pricier
P/B ratio
452.4
18290% above peers (2.5)
vs Peers
vs Industry
Overvalued
Div yield
0% below peers (0.0%)
vs Peers
vs Industry
Low yield

ALNY profitability vs Biotechnology peers

ROE
26.1%
139% above peers (-67.3%)
vs Peers
vs Industry
Top tier
Net margin
1.4%
100% above peers (-286.8%)
vs Peers
vs Industry
Below avg
Gross margin
83.9%
7% above peers (78.6%)
vs Peers
vs Industry
Weak
ROA
1.0%
102% above peers (-46.7%)
vs Peers
vs Industry
Top tier

ALNY financial health vs Biotechnology peers

D/E ratio
1071.1
0% below peers (0.0)
vs Peers
vs Industry
High debt
Current ratio
2.5
43% below peers (4.4)
vs Peers
vs Industry
Low liquidity
Beta
0.3
67% below peers (1.0)
vs Peers
vs Industry
More volatile

ALNY fundamentals radar

ALNY Peer median Industry

ALNY profitability vs leverage

Bubble size = market cap · X = net margin · Y = D/E ratio

ALNY vs peers: key metrics