NTRA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $410.35
Market Cap (MRQ) $58.93B
P/E (TTM) -304.0
EPS (TTM) $-1.35
Revenue (TTM) $2.71B
ROE (TTM) -12.5%
Debt/Equity (MRQ) 0.0
52W Range $167–$427

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About Natera, Inc. - Common Stock Company overview from Wikipedia

05 · wikidata

Natera, Inc. is a clinical genetic testing company based in Austin, Texas that specializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women's health, cancer, and organ health. Natera's proprietary technology combines novel molecular biology techniques with a suite of bioinformatics software that allows detection down to a single molecule in a tube of blood. Natera operates CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in San Carlos, California and Austin, Texas.

History

Natera (previously Gene Security Network) was founded by Matthew Rabinowitz and Jonathan Sheena in 2004. Natera launched its first product, the Spectrum preimplantation genetic test, in 2009.

In 2010, the company introduced the Anora miscarriage (POC) test. Natera's advanced carrier screening test, Horizon, launched in 2012. The following year, 2013, Natera launched the Panorama non-invasive prenatal test (NIPT).

In July 2015, Natera conducted an initial public offering of common stock at a price of $18.00 per share. The shares trade on the Nasdaq Global Select Market under the symbol "NTRA."

In 2017, Natera launched the Vistara single-gene NIPT. That same year, Natera introduced the Signatera molecular residual disease (MRD) test for research use only. The Signatera CLIA test was introduced for clinical use in 2019.

In 2018 Natera paid a $11 million fine to the department over allegations of improper billing and sales of Panorama to federal Healthcare services between the years of 2013 to 2016.

Natera launched the Prospera dd-cfDNA transplant assessment test in 2019, and the Renasight kidney gene panel and the Empower hereditary cancer test in 2020.

As of May 2021, Natera has performed over 3 million cell-free DNA tests. Natera's technology has also been written about in over 200 peer-reviewed journals and publications, including Nature, Science Magazine, and the Journal of Clinical Oncology.

Products and services

Women's health

The Panorama NIPT is the only single-nucleotide polymorphism (SNP)-based NIPT. The test analyzes fetal DNA found in the mother's blood to reveal a baby's risk for genetic disorders such as Down syndrome (trisomy 21) and Edwards syndrome (trisomy 18) as early as nine weeks. Panorama also tests for unique microdeletions and is the only test that can detect zygosity and fetal sex in twins.

Natera also offers Horizon, a carrier-screening test that uses next-generation sequencing to provide carrier status for up to 274 genetic conditions. Additionally, Natera offers the Anora products of conception (POC) miscarriage test, the Spectrum preimplantation genetic screening and diagnosis test, and the Vistara single-gene prenatal screening test. In 2020, Natera launched Empower, a hereditary cancer test that screens for up to 53 genes associated with increased risk for common hereditary cancers.

Oncology

Signatera is the first circulating tumor DNA (ctDNA) assay built for molecular residual disease (MRD) detection and cancer recurrence monitoring. In 2020, Signatera received the CE Mark, as well as final Medicare coverage in stage II-III colorectal cancer and draft coverage in immunotherapy response monitoring. Signatera has been clinically validated to detect colorectal cancer recurrence up to 16.5 months in advance of radiologic imaging and early-stage breast cancer up to two years earlier than imaging.

Organ health

The Prospera test is the first assay with high sensitivity to both T-cell-mediated and antibody-mediated rejection. In December 2019, the test received final Medicare coverage. In 2020, Natera launched Renasight, a test to determine if there is a genetic cause for an individual's kidney disease and if there may be other at-risk relatives.

Constellation

Natera offers a cloud-based bioinformatics platform called Constellation, allowing laboratories to access and use Natera's technology in their own facilities. Constellation is currently only available outside of the United States.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

sectorHealthcare industryBiotechnology employees6,135 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$2.31B
2016-12-31 → 2025-12-31
EPS$-1.52
2016-12-31 → 2025-12-31
Free Cash Flow$109M
2016-12-31 → 2025-12-31
Net margin-7.1%
2016-12-31 → 2025-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend NTRA 5Y avg Peer Median Verdict
P/E (TTM) -304.05Y avg ≈-59.2 ≈-59.2 · ·
P/S (TTM) 21.85Y avg ≈10.6 ≈10.6 7.3 Overvalued
P/B (MRQ) 32.45Y avg ≈13.2 ≈13.2 6.2 Overvalued
Price / FCF (TTM) 699.95Y avg ≈107.5 ≈107.5 · ·
Price / Cash Flow (TTM) 258.25Y avg ≈47.2 ≈47.2 18.3 Overvalued
Price / Tangible Book (MRQ) 40.35Y avg ≈14.8 ≈14.8 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 17.2%
Next Report Nov 04, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 5, 2026 $-0.47 $-0.50 6.7%
March 31, 2026 May 7, 2026 $-0.60 $-0.55 -9.7%
Dec. 31, 2025 $0.36 $-0.52 169.1%
Sept. 30, 2025 $-0.64 $-0.38 -68.2%
June 30, 2025 $-0.74 $-0.63 -17.8%
March 31, 2025 $-0.50 $-0.65 23.1%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 16
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $2.31B$1.70B$1.08B$820M$625M$391M$302M$258M$210M$213M$190M$159M
Cost of Revenue ·······$158M$136M$134M$113M$78M
R&D Expense $624M$404M$321M$316M$264M$100M$51M$51M$50M$42M$28M$17M
SG&A Expense $1.18B$841M$618M$589M$511M$304M$206M$155M$155M$136M$110M$63M
Operating Expenses $2.62B$1.92B$1.53B$1.36B$1.09B$607M$419M$372M$345M$314M$250M$159M
Operating Income $-310M$-222M$-446M$-541M$-468M$-216M$-116M$-115M$-135M$-101M$-60M$665.0K
Interest Expense $4M$11M$13M$9M$8M$15M$11M$10M$4M$533.0K$4M$4M
Other Non-op ··········$-8M$-2M
Pretax Income $-268M$-190M$-435M$-547M$-471M$-230M$-123M$-128M$-137M$-100M$-70M$-5M
Income Tax $-60M$695.0K$271.0K$978.0K$618.0K$98.0K$2M$321.0K$454.0K$142.0K·$15.0K
Net Income $-208M$-190M$-435M$-548M$-472M$-230M$-125M$-128M$-138M$-100M$-70M$-5M
EPS (Basic) $-1.52$-1.53$-3.78$-5.57$-5.21$-2.84$-1.79$-2.22$-2.58$-1.95$-2.68·
EPS (Diluted) $-1.52$-1.53$-3.78$-5.57$-5.21$-2.84$-1.79$-2.22$-2.59$-1.95$-2.68·
Shares (Basic) 136,721,000124,718,000114,997,00098,408,00090,558,00081,011,00069,555,00057,848,00053,312,00051,576,00026,204,000·
Shares (Diluted) 136,721,000124,718,000114,997,00098,408,00090,558,00081,011,00069,555,00057,848,00053,604,00051,576,00026,204,000·
EBITDA $-268M$-191M$-422M$-524M$-457M$-208M$-109M$-107M$-127M$-90M$-54M·
Balance Sheet 28
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents ···$466M$84M$49M$62M$46M$13M$15M$29M$87M
Short-term Investments ·$23M$237M$432M$830M$689M$379M$107M$106M$131M$202M·
Receivables $297M$314M$278M$244M$122M$79M$53M$62M$44M$13M$6M$6M
Inventory $68M$45M$41M$35M$27M$20M$12M$14M$9M$6M$8M$12M
Prepaid Expense $56M$49M$61M$34M$30M$27M$16M$6M$9M$7M$5M$1M
Current Assets $1.50B$1.38B$1.26B$1.21B$1.09B$863M$523M$241M$181M$174M$251M$106M
PP&E (Net) $241M$162M$111M$92M$66M$33M$23M$24M$30M$32M$13M$15M
PP&E (Gross) $352M$240M$168M$128M$85M$83M$65M$59M$57M$52M$26M$24M
Accum. Depreciation $111M$78M$56M$36M$19M$50M$42M$34M$27M$19M$14M$10M
Goodwill $141M···········
Intangibles $374M$11M··········
Other Non-current Assets $37M$26M$15M$18M$19M$15M$12M$3M$4M$4M$1M$2M
Total Assets $2.40B$1.66B$1.44B$1.39B$1.24B$932M$583M$268M$215M$211M$265M$124M
Accounts Payable $33M$35M$15M$31M$27M$8M$9M$15M$9M$11M$7M$9M
Accrued Liabilities ·····$60M$49M$32M$33M$20M$19M$10M
Short-term Debt $80M$80M$80M$80M$50M$50M$50M$50M$50M$50M$42M·
Current Liabilities $441M$344M$307M$310M$219M$199M$180M$114M$106M$96M$80M$30M
Capital Leases $118M$97M$67M$77M$61M$21M$26M·····
Other Non-current Liabilities $12M$8M··$1M$320.0K$310.0K·$1M···
Total Liabilities $686M$465M$676M$689M$583M$446M$304M$236M$189M$104M$80M$54M
Long-term Debt ··$283M$282M$280M·······
Total Debt $80M$80M$80M$80M$50M$50M$50M$50M$50M$50M$42M·
Common Stock $14.0K$12.0K$11.0K$11.0K$10.0K$9.0K$8.0K$7.0K$6.0K$5.0K$5.0K$1.0K
Retained Earnings $-2.78B$-2.57B$-2.38B$-1.94B$-1.39B$-929M$-699M$-575M$-446M$-346M$-250M$-180M
AOCI $-258.0K$-344.0K$-3M$-16M$-2M$4M$919.0K$-552.0K$-766.0K$-725.0K$-1M·
Stockholders' Equity $1.71B$1.20B$765M$706M$653M$486M$279M$32M$25M$144M$226M$-171M
Liabilities + Equity $2.40B$1.66B$1.44B$1.39B$1.24B$932M$583M$268M$215M$211M$265M$124M
Shares Outstanding 139,693,000132,646,000119,581,000111,255,00095,140,00086,223,00078,005,00062,083,00054,040,00052,665,00050,346,0006,879,000
Cash Flow 15
Metric Trend 202520242023202220212020201920182017201620152014
D&A $42M$31M$24M$17M$11M$9M$8M$8M$7M$6M$6M$5M
Stock-based Comp $354M$274M$192M$152M$115M$50M$29M$14M$11M$11M$7M$5M
Amort. of Intangibles $4M$1M$0···$1M$1M$1M$600.0K$200.0K$0
Restructuring ····$400.0K$400.0K······
Other Non-cash $27M$21M$-28M$-53M$10M$-12M$25M$36M$21M$5M$20M·
Operating Cash Flow $215M$136M$-247M$-432M$-335M$-183M$-63M$-71M$-98M$-74M$-38M$10M
CapEx $106M$66M$39M$48M$41M$20M$5M$4M$10M$23M$8M$10M
Investing Cash Flow $-132M$138M$168M$330M$-205M$-331M$-266M$-5M$14M$47M$-211M·
Debt Issued ········$75M···
Net Debt Issued ········$75M···
Financing Cash Flow $47M$30M$254M$483M$576M$501M$341M$114M$80M$13M$190M·
Net Change in Cash ········$-3M$-14M$-58M·
Taxes Paid $499.0K$1M$295.0K$549.0K$283.0K$67.0K$2M$332.0K$177.0K···
Free Cash Flow $109M$69M$-286M$-479M$-376M$-202M$-68M$-74M$-107M$-97M$-46M·
Levered FCF $106M$59M$-299M$-489M$-385M$-217M$-79M$-85M$-111M$-98M··
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin -13.4%-13.1%-41.2%-66.0%-74.9%-55.3%-38.5%-44.5%-63.5%-44.5%-31.4%·
Net Margin -9.0%-11.2%-40.2%-66.8%-75.4%-58.8%-41.3%-49.7%-64.6%-44.1%-36.9%·
Pretax Margin -11.6%-11.2%-40.1%-66.7%-75.3%-58.7%-40.6%-49.6%-64.4%-44.0%··
EBITDA Margin -11.6%-11.3%-39.0%-63.9%-73.0%-53.1%-35.9%-41.6%-60.2%-41.6%-28.5%·
ROA -10.3%-12.3%-30.7%-41.6%-43.5%-30.3%-29.3%-53.1%-70.0%-40.2%-36.1%·
ROE -14.1%-18.4%-56.1%-102.6%-66.8%-45.0%-68.7%-288.9%-204.7%-57.5%-1046.5%·
ROIC -13.4%-17.5%-52.8%-69.0%-66.6%-40.4%-35.9%-139.6%-338.4%-61.9%··
Liquidity & Solvency 4
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 3.44.04.13.95.04.32.92.11.41.83.1·
Quick Ratio 0.71.01.73.74.74.12.71.91.21.72.9·
Debt / Equity 0.00.10.10.10.10.10.21.6-4.80.50.2·
Interest Coverage -76.2-20.8-35.3-58.1-56.4-14.3-10.9-10.9-31.8-181.0-17.1·
Efficiency 3
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 1.11.10.80.60.60.50.71.11.10.91.0·
Inventory Turnover ·······14.017.618.711.5·
Receivables Turnover 7.65.74.14.56.25.95.24.819.522.532.3·
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $12.26$9.01$6.40$6.34$6.87$5.64$3.57$0.52$-0.19$2.02$3.67·
Revenue / Share $16.87$13.61$9.41$8.33$6.91·$4.35$4.45$3.94···
Cash Flow / Share $1.57$1.09$-2.15$-4.38$-3.70·$-0.91$-1.22$-1.81···
Cash / Share ···$4.19$0.89$0.56$0.79$0.75$0.23$0.29$0.57·
EPS (TTM) $-1.52$-1.53$-3.78$-5.57$-5.21$-2.84$-1.79$-2.22$-2.59$-1.95$-2.68·
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 35.9%56.8%32.0%31.1%60.0%·······
Revenue CAGR 3Y 41.1%39.5%40.4%·········
Revenue CAGR 5Y 42.6%···········
Valuation (TTM) 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $2.31B$1.70B$1.08B$820M$625M$391M$302M$258M$210M$213M$190M·
Net Income TTM $-208M$-190M$-435M$-548M$-472M$-230M$-125M$-128M$-138M$-100M$-70M·
Market Cap $32.00B$21.00B$7.49B$4.47B$8.89B$8.58B$2.63B$867M$486M$617M$544M·
Enterprise Value ···$3.65B$8.02B$7.89B$2.24B$763M$417M$520M$355M·
P/E -150.7-103.5-16.6-7.2-17.9-35.0-18.8-6.3-3.5-6.0-4.0·
P/S 13.912.46.95.414.221.98.73.42.32.92.9·
P/B 18.717.69.86.313.617.69.426.9-46.85.82.9·
P / Tangible Book 26.717.79.86.313.617.6······
P / Cash Flow 148.6154.8-30.3-10.4-26.5-47.0-41.4-12.3-5.0-8.3-14.4·
P / FCF 293.3303.3-26.2-9.3-23.6-42.5-38.4-11.6-4.6-6.4-11.9·
EV / EBITDA ···-7.0-17.6-38.0-20.6-7.1-3.3-5.8-6.5·
EV / FCF ···-7.6-21.3-39.1-32.7-10.2-3.9-5.4-7.8·
EV / Revenue ···4.512.820.27.43.02.02.41.9·
Earnings Yield -0.66%-0.97%-6.0%-13.9%-5.6%-2.9%-5.3%-15.9%-28.8%-16.7%-24.8%·

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $2.31B $1.70B $1.08B $820M $625M
Operating Margin % -13.4% -13.1% -41.2% -66.0% -74.9%
Net Income $-208M $-190M $-435M $-548M $-472M
Diluted EPS $-1.52 $-1.53 $-3.78 $-5.57 $-5.21

Institutional owners (13F) 928 filers · $36.5B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 928
Value held $36.5B
New positions 166
Exited positions 63
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
166 (+55 vs prior Q) 63 (-37 vs prior Q) 359 (+56 vs prior Q) 247 (-14 vs prior Q) +8.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
JPMORGAN CHASE & CO $3,505,094,525 12,865,346 9.61% Shares
BlackRock, Inc. $2,962,770,331 10,914,608 8.12% Shares
VANGUARD GROUP INC $2,819,278,675 12,306,424 7.73% Shares
VANGUARD CAPITAL MANAGEMENT LLC $1,690,649,234 6,228,216 4.63% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $1,569,697,628 5,782,640 4.30% Shares
FMR LLC $1,479,781,281 5,451,396 4.06% Shares
WELLINGTON MANAGEMENT GROUP LLP $1,096,858,330 4,040,738 3.01% Shares
STATE STREET CORP $992,317,506 3,655,618 2.72% Shares
GEODE CAPITAL MANAGEMENT, LLC $744,565,293 2,750,013 2.04% Shares
FRANKLIN RESOURCES INC $739,946,472 2,725,903 2.03% Shares
Castle Hook Partners LP $704,759,120 2,596,276 1.93% Shares
COATUE MANAGEMENT LLC $680,006,681 2,505,090 1.86% Shares
AQR CAPITAL MANAGEMENT LLC $628,086,698 2,344,570 1.72% Shares
FARALLON CAPITAL MANAGEMENT, L.L.C. $602,175,451 2,218,366 1.65% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $535,084,922 1,971,391 1.47% Shares
NORGES BANK $496,243,717 1,828,122 1.36% Shares
FRED ALGER MANAGEMENT, LLC $482,640,543 1,778,009 1.32% Shares
GOLDMAN SACHS GROUP INC $466,935,338 1,720,152 1.28% Shares
Sofinnova Investments, Inc. $420,823,506 1,550,280 1.15% Shares
Capital World Investors $408,365,851 1,504,387 1.12% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $408,180,994 1,503,706 1.12% Shares
MAVERICK CAPITAL LTD $368,266,171 1,356,663 1.01% Shares
D. E. Shaw & Co., Inc. $347,253,770 1,279,255 0.95% Shares
MORGAN STANLEY $345,906,057 1,274,287 0.95% Shares
FEDERATED HERMES, INC. $309,172,863 1,138,968 0.85% Shares
Clearbridge Investments, LLC $276,424,438 1,018,325 0.76% Shares
RTW INVESTMENTS, LP $271,450,000 1,000,000 0.74% Shares
JANE STREET GROUP, LLC $251,630,350 926,986 0.69% Shares
VANGUARD FIDUCIARY TRUST CO $249,356,413 918,609 0.68% Shares
Invesco Ltd. $237,065,949 873,332 0.65% Shares
NORTHERN TRUST CORP $227,070,096 836,508 0.62% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $218,934,197 806,536 0.60% Shares
BANK OF AMERICA CORP /DE/ $199,960,146 736,637 0.55% Shares
WESTFIELD CAPITAL MANAGEMENT CO LP $197,243,187 726,628 0.54% Shares
ARK Investment Management LLC $186,989,592 688,855 0.51% Shares
Sumitomo Mitsui Trust Group, Inc. $174,716,892 643,643 0.48% Shares
Chevy Chase Trust Holdings, LLC $162,830,912 599,856 0.45% Shares
RAYMOND JAMES FINANCIAL INC $160,992,382 593,083 0.44% Shares
WORLDQUANT MILLENNIUM ADVISORS LLC $160,551,817 591,460 0.44% Shares
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $150,579,670 752,936 0.41% Shares
UBS Group AG $150,312,452 553,739 0.41% Shares
Legal & General Group Plc $150,142,799 553,114 0.41% Shares
Bank of New York Mellon Corp $149,277,609 549,927 0.41% Shares
FIRST TRUST ADVISORS LP $138,768,953 511,214 0.38% Shares
WELLS FARGO & COMPANY/MN $136,489,991 502,818 0.37% Shares
Nuveen, LLC $135,477,536 499,089 0.37% Shares
GILDER GAGNON HOWE & CO LLC $135,199,396 498,064 0.37% Shares
AMERICAN CENTURY COMPANIES INC $129,951,802 478,732 0.36% Shares
VICTORY CAPITAL MANAGEMENT INC $125,949,543 463,988 0.35% Shares
Avala Global LP $124,867,000 460,000 0.34% Shares

Show all 928 institutional owners →

Activists & 5%+ owners 1 position

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Sofinnova Venture Partners VIII, L.P. (“SVP VIII”), Sofinnova Management VIII, L.L.C., Sofinnova Venture Partners IX, L.P. (“SVP IX”), Sofinnova Management IX, L.L.C., Dr. Michael F. Powell (“Powell”), Dr. James I. Healy ×3 filings Feb. 13, 2020 · Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 21 insiders · 7 officers · 15 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Steven Leonard Chapman CEO AND PRESIDENT Oct. 1, 2026 S 96,926 0 54 $-90,749,334
Michael Burkes Brophy CHIEF FINANCIAL OFFICER Aug. 4, 2026 S 51,637 0 41 $-21,731,496
Solomon Moshkevich PRESIDENT, CLINICALDIAGNOSTICS Oct. 1, 2026 S 106,914 0 64 $-23,640,470
John Fesko PRESIDENT, CHIEF BUS. OFFICER Aug. 10, 2026 S 197,257 0 18 $-9,345,666
Robert Alan Schueren CHIEF OPERATING OFFICER Jan. 27, 2023 A 24,091 0 0 $0
Matthew Rabinowitz EXECUTIVE CHAIRMAN Sept. 15, 2026 S 0 0 92 $-124,045,289
Daniel Rabinowitz SEC. AND CHIEF LEGAL OFFICER Aug. 3, 2026 S 170,073 0 41 $-23,609,158
Jonathan Sheena Director Sept. 23, 2026 S 9,000 0 144 $-29,839,868
Rowan E Chapman Director July 15, 2026 S 4,663 0 5 $-1,764,386
Eric H Rubin Director June 26, 2026 A 2,204 0 0 $0
Monica Bertagnolli Director June 26, 2026 A 7,020 0 0 $0
Gail Boxer Marcus Director June 26, 2026 A 7,852 0 5 $-2,413,550
Roy D. Baynes Director June 26, 2026 A 20,158 0 8 $-2,809,687
Thomas J. Lynch Jr. Director June 26, 2026 A 1,905 0 0 $0
Herm Rosenman Director June 26, 2026 A 5,927 0 5 $-15,143,996
ROELOF BOTHA ("RB") Director June 26, 2026 A 4,585 0 17 $-34,892,929
Dr. James I. Healy Director April 25, 2025 A 46,260 0 0 $0
Todd C Cozzens Director May 25, 2022 M 15,813 0 0 $0
John Steuart Director May 16, 2019 M 7,278 0 0 $0
Edward C. Driscoll Jr. Director May 16, 2019 M 52,009 0 0 $0
Ruth Williams Brinkley · April 24, 2026 A 5,475 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 75 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PBE · Invesco Exchange-Traded Fund Trust 6.29% 63,892 SH Oct. 2, 2026 Daily
ARKG · ARK ETF Trust 4.13% 240,145 NS July 31, 2026 N-PORT
PTH · Invesco Exchange-Traded Fund Trust 3.82% 26,940 SH Oct. 2, 2026 Daily
IBB · iShares Trust 3.30% 1,043,662 SH Sept. 11, 2026 Daily
QQQJ · Invesco Exchange-Traded Fund Trust … 2.95% 85,185 SH Oct. 2, 2026 Daily
MEDI · Harbor ETF Trust 2.26% 3,475 NS July 31, 2026 N-PORT
FXH · First Trust Exchange-Traded AlphaDE… 2.23% 87,424 NS July 31, 2026 N-PORT
HTEC · EXCHANGE TRADED CONCEPTS TRUST 2.23% 5,764 NS July 31, 2026 N-PORT
HFGO · Hartford Funds Exchange-Traded Trust 1.74% 13,080 NS July 31, 2026 N-PORT
PDP · Invesco Exchange-Traded Fund Trust 1.58% 57,481 SH Oct. 2, 2026 Daily
GURU · Global X Funds 1.52% 3,466 NS July 31, 2026 N-PORT
IWP · iShares Trust 1.31% 769,818 SH Sept. 11, 2026 Daily
ARKK · ARK ETF Trust 1.24% 257,162 NS July 31, 2026 N-PORT
VBK · VANGUARD INDEX FUNDS 1.01% 1,802,288 SH Aug. 19, 2026 Daily
HQGO · Lattice Strategies Trust 0.86% 1,588 NS July 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.84% 15,588 NS July 31, 2026 N-PORT
LSEQ · Harbor ETF Trust 0.80% 460 NS July 31, 2026 N-PORT
BBMC · J.P. Morgan Exchange-Traded Fund Tr… 0.79% 59,919 NS July 31, 2026 N-PORT
FTC · First Trust Exchange-Traded AlphaDE… 0.77% 37,874 NS July 31, 2026 N-PORT
TEXN · iShares Trust 0.74% 426 SH Sept. 11, 2026 Daily
IYH · iShares Trust 0.72% 79,898 SH Sept. 11, 2026 Daily
IMCG · iShares Trust 0.62% 75,541 SH Sept. 11, 2026 Daily
VHT · VANGUARD WORLD FUND 0.54% 404,713 SH Aug. 19, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.52% 64,051 NS July 31, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.44% 1,643,356 SH Aug. 19, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.44% 3,120,454 SH Aug. 19, 2026 Daily
LQAI · Exchange Listed Funds Trust 0.41% 34 NS July 31, 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0.38% 8,233 NS July 31, 2026 N-PORT
FEX · First Trust Exchange-Traded AlphaDE… 0.36% 20,763 NS July 31, 2026 N-PORT
ROUS · Lattice Strategies Trust 0.35% 9,234 NS July 31, 2026 N-PORT
IWR · iShares Trust 0.33% 559,634 SH Sept. 11, 2026 Daily
SIZE · iShares Trust 0.32% 4,182 SH Sept. 11, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.31% 20,376 SH Oct. 2, 2026 Daily
IMCB · iShares Trust 0.31% 15,983 SH Sept. 11, 2026 Daily
JMOM · J.P. Morgan Exchange-Traded Fund Tr… 0.30% 27,638 NS July 31, 2026 N-PORT
PWS · Pacer Funds Trust 0.24% 213 NS July 31, 2026 N-PORT
EUSA · iShares, Inc. 0.20% 12,005 SH Sept. 11, 2026 Daily
ILCG · iShares Trust 0.14% 13,232 SH Sept. 11, 2026 Daily
IWF · iShares Trust 0.14% 513,245 SH Sept. 11, 2026 Daily
VEGN · ETF Series Solutions 0.12% 801 NS July 31, 2026 N-PORT
EQAL · Invesco Exchange-Traded Fund Trust … 0.12% 2,318 SH Oct. 2, 2026 Daily
HEQQ · J.P. Morgan Exchange-Traded Fund Tr… 0.12% 132 NS July 31, 2026 N-PORT
VONG · VANGUARD SCOTTSDALE FUNDS 0.11% 216,186 SH Aug. 19, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.10% 7,532 SH Aug. 19, 2026 Daily
HAPI · Harbor ETF Trust 0.10% 1,778 NS July 31, 2026 N-PORT
PBUS · Invesco Exchange-Traded Fund Trust … 0.08% 23,570 SH Oct. 2, 2026 Daily
USCL · iShares Trust 0.08% 7,220 SH Sept. 11, 2026 Daily
GARP · iShares Trust 0.07% 7,023 SH Sept. 11, 2026 Daily
ILCB · iShares Trust 0.07% 2,633 SH Sept. 11, 2026 Daily
IYY · iShares Trust 0.07% 6,130 SH Sept. 11, 2026 Daily
ITOT · iShares Trust 0.06% 187,328 SH Sept. 11, 2026 Daily
IWB · iShares Trust 0.06% 95,076 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.06% 37,512 SH Sept. 11, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.06% 30,869 SH Aug. 19, 2026 Daily
BKLC · BNY Mellon ETF Trust 0.06% 11,523 NS July 31, 2026 N-PORT
VOTE · TCW ETF Trust 0.06% 2,309 NS July 31, 2026 N-PORT
DFUS · Dimensional ETF Trust 0.05% 42,084 NS July 31, 2026 N-PORT
RECS · Columbia ETF Trust I 0.05% 11,689 NS July 31, 2026 N-PORT
TOK · iShares Trust 0.05% 379 SH Sept. 11, 2026 Daily
VTI · VANGUARD INDEX FUNDS 0.05% 4,321,128 SH Aug. 19, 2026 Daily
VONE · VANGUARD SCOTTSDALE FUNDS 0.05% 22,505 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.05% 11,503 SH Aug. 19, 2026 Daily
TOV · EA Series Trust 0.05% 479 NS July 31, 2026 N-PORT
URTH · iShares, Inc. 0.05% 11,995 SH Sept. 11, 2026 Daily
CRBN · iShares Trust 0.05% 1,666 SH Sept. 11, 2026 Daily
ACWI · iShares Trust 0.04% 42,227 SH Sept. 11, 2026 Daily
TILT · FlexShares Trust 0.04% 3,402 NS July 31, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.04% 3,537 NS July 31, 2026 N-PORT
DFAU · Dimensional ETF Trust 0.04% 18,510 NS July 31, 2026 N-PORT
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.03% 113,866 SH Aug. 19, 2026 Daily
DCOR · Dimensional ETF Trust 0.03% 3,396 NS July 31, 2026 N-PORT
DFAC · Dimensional ETF Trust 0.02% 42,957 NS July 31, 2026 N-PORT
HDUS · Lattice Strategies Trust 0.02% 132 NS July 31, 2026 N-PORT
OMFL · Invesco Exchange-Traded Self-Indexe… 0.01% 1,514 SH Oct. 2, 2026 Daily
SMLF · iShares Trust · 96,755 SH Sept. 11, 2026 Daily

NTRA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 30 analysts BUY
Median target $360.00 -12.3%
12 40.0% Strong Buy
14 46.7% Buy
4 13.3% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

23 analysts · 2026-09-28

Mean target $352.80 -14.0%

Now Current price $410.35
Low$280.00 Mean$352.80 High$460.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
NTRA $32.00B -150.7 35.9% -9.0% -14.1% ·
GILD $152.32B 18.1 2.4% 28.9% 40.5% ·
VRTX $115.15B 29.6 8.9% 32.9% 22.1% ·
MRNA $11.62B -4.1 -39.9% -145.2% -31.3% ·
REGN $106.21B 18.6 0.99% 31.4% 14.7% ·
RVMD · · · · · ·
BIIB $25.84B 20.0 2.2% 13.1% 7.2% ·
ALNY $52.64B 170.7 65.2% 8.5% 60.4% ·
INSM $37.29B -27.1 66.7% -210.5% -128.4% ·
INCY $19.60B 15.4 21.2% 25.0% 27.6% ·

Latest News Recent headlines mentioning this company

23

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Source: SEC 10-Q filed Aug 7, 2026