NTRA Natera, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$315.20
Price · Aug 19, 2026
Fundamentals as of Aug 7, 2026

About Natera, Inc. - Common Stock Company overview from Wikipedia

Natera, Inc. is a clinical genetic testing company based in Austin, Texas that specializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women's health, cancer, and organ health. Natera's proprietary technology combines novel molecular biology techniques with a suite of bioinformatics software that allows detection down to a single molecule in a tube of blood. Natera operates CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in San Carlos, California and Austin, Texas.

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Natera, Inc. is a clinical genetic testing company based in Austin, Texas that specializes in non-invasive, cell-free DNA (cfDNA) testing technology, with a focus on women's health, cancer, and organ health. Natera's proprietary technology combines novel molecular biology techniques with a suite of bioinformatics software that allows detection down to a single molecule in a tube of blood. Natera operates CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in San Carlos, California and Austin, Texas.

History

Natera (previously Gene Security Network) was founded by Matthew Rabinowitz and Jonathan Sheena in 2004. Natera launched its first product, the Spectrum preimplantation genetic test, in 2009.

In 2010, the company introduced the Anora miscarriage (POC) test. Natera's advanced carrier screening test, Horizon, launched in 2012. The following year, 2013, Natera launched the Panorama non-invasive prenatal test (NIPT).

In July 2015, Natera conducted an initial public offering of common stock at a price of $18.00 per share. The shares trade on the Nasdaq Global Select Market under the symbol "NTRA."

In 2017, Natera launched the Vistara single-gene NIPT. That same year, Natera introduced the Signatera molecular residual disease (MRD) test for research use only. The Signatera CLIA test was introduced for clinical use in 2019.

In 2018 Natera paid a $11 million fine to the department over allegations of improper billing and sales of Panorama to federal Healthcare services between the years of 2013 to 2016.

Natera launched the Prospera dd-cfDNA transplant assessment test in 2019, and the Renasight kidney gene panel and the Empower hereditary cancer test in 2020.

As of May 2021, Natera has performed over 3 million cell-free DNA tests. Natera's technology has also been written about in over 200 peer-reviewed journals and publications, including Nature, Science Magazine, and the Journal of Clinical Oncology.

Products and services

Women's health

The Panorama NIPT is the only single-nucleotide polymorphism (SNP)-based NIPT. The test analyzes fetal DNA found in the mother's blood to reveal a baby's risk for genetic disorders such as Down syndrome (trisomy 21) and Edwards syndrome (trisomy 18) as early as nine weeks. Panorama also tests for unique microdeletions and is the only test that can detect zygosity and fetal sex in twins.

Natera also offers Horizon, a carrier-screening test that uses next-generation sequencing to provide carrier status for up to 274 genetic conditions. Additionally, Natera offers the Anora products of conception (POC) miscarriage test, the Spectrum preimplantation genetic screening and diagnosis test, and the Vistara single-gene prenatal screening test. In 2020, Natera launched Empower, a hereditary cancer test that screens for up to 53 genes associated with increased risk for common hereditary cancers.

Oncology

Signatera is the first circulating tumor DNA (ctDNA) assay built for molecular residual disease (MRD) detection and cancer recurrence monitoring. In 2020, Signatera received the CE Mark, as well as final Medicare coverage in stage II-III colorectal cancer and draft coverage in immunotherapy response monitoring. Signatera has been clinically validated to detect colorectal cancer recurrence up to 16.5 months in advance of radiologic imaging and early-stage breast cancer up to two years earlier than imaging.

Organ health

The Prospera test is the first assay with high sensitivity to both T-cell-mediated and antibody-mediated rejection. In December 2019, the test received final Medicare coverage. In 2020, Natera launched Renasight, a test to determine if there is a genetic cause for an individual's kidney disease and if there may be other at-risk relatives.

Constellation

Natera offers a cloud-based bioinformatics platform called Constellation, allowing laboratories to access and use Natera's technology in their own facilities. Constellation is currently only available outside of the United States.

Source: Wikipedia, CC BY-SA 4.0 · View on Wikipedia ↗

Wikidata ↗

NTRA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$315.20
Market Cap
$44.03B
P/E (TTM)
-207.4
EPS (TTM)
$-1.52
Revenue (TTM)
$2.31B
Div Yield
ROE
-14.1%
Debt/Equity
0.0
52W Range
$157 – $326

NTRA Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $2.31B
10-point trend, +985.2%
2016-12-31 2025-12-31
EPS $-1.52
10-point trend, +22.1%
2016-12-31 2025-12-31
Free Cash Flow $109M
10-point trend, +212.4%
2016-12-31 2025-12-31
Margins -9.0%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
NTRA
Peer Median
P/E (TTM)
5-point trend, -740.8%
-207.4
17.7
P/S (TTM)
5-point trend, -2.3%
19.1
6.8
P/B
5-point trend, +37.4%
25.7
6.4
Price / FCF
5-point trend, +1342.0%
403.5

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
NTRA
Peer Median
Operating Margin
5-point trend, +82.0%
-13.4%
Net Profit Margin
5-point trend, +88.0%
-9.0%
20.3%
ROA
5-point trend, +76.4%
-10.3%
11.4%
ROE
5-point trend, +78.9%
-14.1%
16.8%
ROIC
5-point trend, +79.9%
-13.4%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
NTRA
Peer Median
Debt / Equity
5-point trend, -38.8%
0.0
Current Ratio
5-point trend, -32.0%
3.4
3.4
Quick Ratio
5-point trend, -85.8%
0.7

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
NTRA
Peer Median
Revenue YoY
5-point trend, +268.7%
35.9%
Revenue CAGR 3Y
5-point trend, +268.7%
41.1%
Revenue CAGR 5Y
5-point trend, +268.7%
42.6%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
NTRA
Peer Median
EPS (Diluted)
5-point trend, +70.8%
$-1.52

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
NTRA
Peer Median

NTRA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 30 analysts
  • Strong Buy 12 40.0%
  • Buy 14 46.7%
  • Hold 4 13.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

21 analysts · 2026-08-17
Median target $348.00 +10.4%
Mean target $330.64 +4.9%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.11%
Period EPS Actual EPS Est Surprise
June 30, 2026 $-0.47 $-0.50 0.03%
March 31, 2026 $-0.60 $-0.55 -0.05%
Dec. 31, 2025 $0.36 $-0.52 0.88%
Sept. 30, 2025 $-0.64 $-0.38 -0.26%
June 30, 2025 $-0.74 $-0.63 -0.11%
March 31, 2025 $-0.50 $-0.65 0.15%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
NTRA $32.00B -150.7 35.9% -9.0% -14.1%
GILD $152.32B 18.1 2.4% 28.9% 40.5%
VRTX $115.15B 29.6 8.9% 32.9% 22.1%
REGN $106.21B 18.6 0.99% 31.4% 14.7%
RVMD
BIIB $25.84B 20.0 2.2% 13.1% 7.2%
ALNY $52.64B 170.7 65.2% 8.5% 60.4%
INSM $37.29B -27.1 66.7% -210.5% -128.4%
INCY $19.60B 15.4 21.2% 25.0% 27.6%
MRNA $11.62B -4.1 -39.9% -145.2% -31.3%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +1347.8% $2.31B $1.70B $1.08B $820M $625M $391M $302M $258M $210M $213M $190M $159M
Cost of Revenue 5-point trend, +101.6% · · · · · · · $158M $136M $134M $113M $78M
R&D Expense 12-point trend, +3509.2% $624M $404M $321M $316M $264M $100M $51M $51M $50M $42M $28M $17M
SG&A Expense 12-point trend, +1770.6% $1.18B $841M $618M $589M $511M $304M $206M $155M $155M $136M $110M $63M
Operating Expenses 12-point trend, +1549.2% $2.62B $1.92B $1.53B $1.36B $1.09B $607M $419M $372M $345M $314M $250M $159M
Operating Income 12-point trend, -46703.2% $-310M $-222M $-446M $-541M $-468M $-216M $-116M $-115M $-135M $-101M $-60M $665.0K
Interest Expense 12-point trend, -3.6% $4M $11M $13M $9M $8M $15M $11M $10M $4M $533.0K $4M $4M
Other Non-op 2-point trend, -360.1% · · · · · · · · · · $-8M $-2M
Pretax Income 12-point trend, -5103.6% $-268M $-190M $-435M $-547M $-471M $-230M $-123M $-128M $-137M $-100M $-70M $-5M
Income Tax 11-point trend, -399626.7% $-60M $695.0K $271.0K $978.0K $618.0K $98.0K $2M $321.0K $454.0K $142.0K · $15.0K
Net Income 12-point trend, -3940.4% $-208M $-190M $-435M $-548M $-472M $-230M $-125M $-128M $-138M $-100M $-70M $-5M
EPS (Basic) 11-point trend, +43.3% $-1.52 $-1.53 $-3.78 $-5.57 $-5.21 $-2.84 $-1.79 $-2.22 $-2.58 $-1.95 $-2.68 ·
EPS (Diluted) 11-point trend, +43.3% $-1.52 $-1.53 $-3.78 $-5.57 $-5.21 $-2.84 $-1.79 $-2.22 $-2.59 $-1.95 $-2.68 ·
Shares (Basic) 11-point trend, +421.8% 136,721,000 124,718,000 114,997,000 98,408,000 90,558,000 81,011,000 69,555,000 57,848,000 53,312,000 51,576,000 26,204,000 ·
Shares (Diluted) 11-point trend, +421.8% 136,721,000 124,718,000 114,997,000 98,408,000 90,558,000 81,011,000 69,555,000 57,848,000 53,604,000 51,576,000 26,204,000 ·
EBITDA 11-point trend, -393.8% $-268M $-191M $-422M $-524M $-457M $-208M $-109M $-107M $-127M $-90M $-54M ·
Balance Sheet 28
Annual Balance Sheet data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 9-point trend, +434.6% · · · $466M $84M $49M $62M $46M $13M $15M $29M $87M
Short-term Investments 10-point trend, -88.7% · $23M $237M $432M $830M $689M $379M $107M $106M $131M $202M ·
Receivables 12-point trend, +4890.4% $297M $314M $278M $244M $122M $79M $53M $62M $44M $13M $6M $6M
Inventory 12-point trend, +493.0% $68M $45M $41M $35M $27M $20M $12M $14M $9M $6M $8M $12M
Prepaid Expense 12-point trend, +4148.7% $56M $49M $61M $34M $30M $27M $16M $6M $9M $7M $5M $1M
Current Assets 12-point trend, +1305.9% $1.50B $1.38B $1.26B $1.21B $1.09B $863M $523M $241M $181M $174M $251M $106M
PP&E (Net) 12-point trend, +1554.9% $241M $162M $111M $92M $66M $33M $23M $24M $30M $32M $13M $15M
PP&E (Gross) 12-point trend, +1357.6% $352M $240M $168M $128M $85M $83M $65M $59M $57M $52M $26M $24M
Accum. Depreciation 12-point trend, +1057.8% $111M $78M $56M $36M $19M $50M $42M $34M $27M $19M $14M $10M
Goodwill $141M · · · · · · · · · · ·
Intangibles 2-point trend, +3318.2% $374M $11M · · · · · · · · · ·
Other Non-current Assets 12-point trend, +1991.7% $37M $26M $15M $18M $19M $15M $12M $3M $4M $4M $1M $2M
Total Assets 12-point trend, +1840.0% $2.40B $1.66B $1.44B $1.39B $1.24B $932M $583M $268M $215M $211M $265M $124M
Accounts Payable 12-point trend, +273.9% $33M $35M $15M $31M $27M $8M $9M $15M $9M $11M $7M $9M
Accrued Liabilities 7-point trend, +484.2% · · · · · $60M $49M $32M $33M $20M $19M $10M
Short-term Debt 11-point trend, +90.8% $80M $80M $80M $80M $50M $50M $50M $50M $50M $50M $42M ·
Current Liabilities 12-point trend, +1377.1% $441M $344M $307M $310M $219M $199M $180M $114M $106M $96M $80M $30M
Capital Leases 7-point trend, +350.5% $118M $97M $67M $77M $61M $21M $26M · · · · ·
Other Non-current Liabilities 6-point trend, +779.4% $12M $8M · · $1M $320.0K $310.0K · $1M · · ·
Total Liabilities 12-point trend, +1162.2% $686M $465M $676M $689M $583M $446M $304M $236M $189M $104M $80M $54M
Long-term Debt 3-point trend, +0.9% · · $283M $282M $280M · · · · · · ·
Total Debt 11-point trend, +90.8% $80M $80M $80M $80M $50M $50M $50M $50M $50M $50M $42M ·
Common Stock 12-point trend, +1300.0% $14.0K $12.0K $11.0K $11.0K $10.0K $9.0K $8.0K $7.0K $6.0K $5.0K $5.0K $1.0K
Retained Earnings 12-point trend, -1443.9% $-2.78B $-2.57B $-2.38B $-1.94B $-1.39B $-929M $-699M $-575M $-446M $-346M $-250M $-180M
AOCI 11-point trend, +81.8% $-258.0K $-344.0K $-3M $-16M $-2M $4M $919.0K $-552.0K $-766.0K $-725.0K $-1M ·
Stockholders' Equity 12-point trend, +1099.5% $1.71B $1.20B $765M $706M $653M $486M $279M $32M $25M $144M $226M $-171M
Liabilities + Equity 12-point trend, +1840.0% $2.40B $1.66B $1.44B $1.39B $1.24B $932M $583M $268M $215M $211M $265M $124M
Shares Outstanding 12-point trend, +1930.7% 139,693,000 132,646,000 119,581,000 111,255,000 95,140,000 86,223,000 78,005,000 62,083,000 54,040,000 52,665,000 50,346,000 6,879,000
Cash Flow 15
Annual Cash Flow data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, +711.3% $42M $31M $24M $17M $11M $9M $8M $8M $7M $6M $6M $5M
Stock-based Comp 12-point trend, +6772.3% $354M $274M $192M $152M $115M $50M $29M $14M $11M $11M $7M $5M
Amort. of Intangibles 9-point trend, +3900000.00 $4M $1M $0 · · · $1M $1M $1M $600.0K $200.0K $0
Restructuring Flat — no change across 2 periods · · · · $400.0K $400.0K · · · · · ·
Other Non-cash 11-point trend, +39.4% $27M $21M $-28M $-53M $10M $-12M $25M $36M $21M $5M $20M ·
Operating Cash Flow 12-point trend, +1952.4% $215M $136M $-247M $-432M $-335M $-183M $-63M $-71M $-98M $-74M $-38M $10M
CapEx 12-point trend, +966.5% $106M $66M $39M $48M $41M $20M $5M $4M $10M $23M $8M $10M
Investing Cash Flow 11-point trend, +37.2% $-132M $138M $168M $330M $-205M $-331M $-266M $-5M $14M $47M $-211M ·
Debt Issued · · · · · · · · $75M · · ·
Net Debt Issued · · · · · · · · $75M · · ·
Financing Cash Flow 11-point trend, -75.1% $47M $30M $254M $483M $576M $501M $341M $114M $80M $13M $190M ·
Net Change in Cash 3-point trend, +95.5% · · · · · · · · $-3M $-14M $-58M ·
Taxes Paid 9-point trend, +181.9% $499.0K $1M $295.0K $549.0K $283.0K $67.0K $2M $332.0K $177.0K · · ·
Free Cash Flow 11-point trend, +338.8% $109M $69M $-286M $-479M $-376M $-202M $-68M $-74M $-107M $-97M $-46M ·
Levered FCF 10-point trend, +208.6% $106M $59M $-299M $-489M $-385M $-217M $-79M $-85M $-111M $-98M · ·
Profitability 7
Annual Profitability data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +57.2% -13.4% -13.1% -41.2% -66.0% -74.9% -55.3% -38.5% -44.5% -63.5% -44.5% -31.4% ·
Net Margin 11-point trend, +75.5% -9.0% -11.2% -40.2% -66.8% -75.4% -58.8% -41.3% -49.7% -64.6% -44.1% -36.9% ·
Pretax Margin 10-point trend, +73.6% -11.6% -11.2% -40.1% -66.7% -75.3% -58.7% -40.6% -49.6% -64.4% -44.0% · ·
EBITDA Margin 11-point trend, +59.2% -11.6% -11.3% -39.0% -63.9% -73.0% -53.1% -35.9% -41.6% -60.2% -41.6% -28.5% ·
ROA 11-point trend, +71.6% -10.3% -12.3% -30.7% -41.6% -43.5% -30.3% -29.3% -53.1% -70.0% -40.2% -36.1% ·
ROE 11-point trend, +98.7% -14.1% -18.4% -56.1% -102.6% -66.8% -45.0% -68.7% -288.9% -204.7% -57.5% -1046.5% ·
ROIC 10-point trend, +78.3% -13.4% -17.5% -52.8% -69.0% -66.6% -40.4% -35.9% -139.6% -338.4% -61.9% · ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, +8.9% 3.4 4.0 4.1 3.9 5.0 4.3 2.9 2.1 1.4 1.8 3.1 ·
Quick Ratio 11-point trend, -77.1% 0.7 1.0 1.7 3.7 4.7 4.1 2.7 1.9 1.2 1.7 2.9 ·
Debt / Equity 11-point trend, -79.4% 0.0 0.1 0.1 0.1 0.1 0.1 0.2 1.6 -4.8 0.5 0.2 ·
Interest Coverage 11-point trend, -346.1% -76.2 -20.8 -35.3 -58.1 -56.4 -14.3 -10.9 -10.9 -31.8 -181.0 -17.1 ·
Efficiency 3
Annual Efficiency data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, +16.1% 1.1 1.1 0.8 0.6 0.6 0.5 0.7 1.1 1.1 0.9 1.0 ·
Inventory Turnover 4-point trend, +21.5% · · · · · · · 14.0 17.6 18.7 11.5 ·
Receivables Turnover 11-point trend, -76.6% 7.6 5.7 4.1 4.5 6.2 5.9 5.2 4.8 19.5 22.5 32.3 ·
Per Share 5
Annual Per Share data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, +234.0% $12.26 $9.01 $6.40 $6.34 $6.87 $5.64 $3.57 $0.52 $-0.19 $2.02 $3.67 ·
Revenue / Share 8-point trend, +328.6% $16.87 $13.61 $9.41 $8.33 $6.91 · $4.35 $4.45 $3.94 · · ·
Cash Flow / Share 8-point trend, +187.2% $1.57 $1.09 $-2.15 $-4.38 $-3.70 · $-0.91 $-1.22 $-1.81 · · ·
Cash / Share 8-point trend, +628.5% · · · $4.19 $0.89 $0.56 $0.79 $0.75 $0.23 $0.29 $0.57 ·
EPS (TTM) 11-point trend, +43.3% $-1.52 $-1.53 $-3.78 $-5.57 $-5.21 $-2.84 $-1.79 $-2.22 $-2.59 $-1.95 $-2.68 ·
Growth Rates 3
Annual Growth Rates data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -40.1% 35.9% 56.8% 32.0% 31.1% 60.0% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +1.8% 41.1% 39.5% 40.4% · · · · · · · · ·
Revenue CAGR 5Y 42.6% · · · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for NTRA
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 11-point trend, +1111.5% $2.31B $1.70B $1.08B $820M $625M $391M $302M $258M $210M $213M $190M ·
Net Income TTM 11-point trend, -196.2% $-208M $-190M $-435M $-548M $-472M $-230M $-125M $-128M $-138M $-100M $-70M ·
Market Cap 11-point trend, +5785.6% $32.00B $21.00B $7.49B $4.47B $8.89B $8.58B $2.63B $867M $486M $617M $544M ·
Enterprise Value 8-point trend, +927.6% · · · $3.65B $8.02B $7.89B $2.24B $763M $417M $520M $355M ·
P/E 11-point trend, -3640.0% -150.7 -103.5 -16.6 -7.2 -17.9 -35.0 -18.8 -6.3 -3.5 -6.0 -4.0 ·
P/S 11-point trend, +385.8% 13.9 12.4 6.9 5.4 14.2 21.9 8.7 3.4 2.3 2.9 2.9 ·
P/B 11-point trend, +535.0% 18.7 17.6 9.8 6.3 13.6 17.6 9.4 26.9 -46.8 5.8 2.9 ·
P / Tangible Book 6-point trend, +51.4% 26.7 17.7 9.8 6.3 13.6 17.6 · · · · · ·
P / Cash Flow 11-point trend, +1134.2% 148.6 154.8 -30.3 -10.4 -26.5 -47.0 -41.4 -12.3 -5.0 -8.3 -14.4 ·
P / FCF 11-point trend, +2564.2% 293.3 303.3 -26.2 -9.3 -23.6 -42.5 -38.4 -11.6 -4.6 -6.4 -11.9 ·
EV / EBITDA 8-point trend, -6.4% · · · -7.0 -17.6 -38.0 -20.6 -7.1 -3.3 -5.8 -6.5 ·
EV / FCF 8-point trend, +2.0% · · · -7.6 -21.3 -39.1 -32.7 -10.2 -3.9 -5.4 -7.8 ·
EV / Revenue 8-point trend, +138.5% · · · 4.5 12.8 20.2 7.4 3.0 2.0 2.4 1.9 ·
Earnings Yield 11-point trend, +97.3% -0.66% -0.97% -6.0% -13.9% -5.6% -2.9% -5.3% -15.9% -28.8% -16.7% -24.8% ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $2.31B$1.70B$1.08B$820M$625M
Operating Margin % -13.4%-13.1%-41.2%-66.0%-74.9%
Net Income $-208M$-190M$-435M$-548M$-472M
Diluted EPS $-1.52$-1.53$-3.78$-5.57$-5.21
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.00.10.10.10.1
Current Ratio 3.44.04.13.95.0
Quick Ratio 0.71.01.73.74.7
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $109M$69M$-286M$-479M$-376M

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Institutional owners (13F) 935 filers · $20.5B total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
172 (+66 vs prior Q) 63 (-37 vs prior Q) 340 (+35 vs prior Q) 248 (-6 vs prior Q) +27.7M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
VANGUARD CAPITAL MANAGEMENT LLC $1,690,649,234 6,228,216 8.25% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $1,569,697,628 5,782,640 7.66% Shares
FMR LLC $1,189,034,607 4,380,308 5.80% Shares
STATE STREET CORP $992,317,506 3,655,618 4.84% Shares
WELLINGTON MANAGEMENT GROUP LLP $965,965,683 3,558,540 4.71% Shares
Castle Hook Partners LP $704,759,120 2,596,276 3.44% Shares
GEODE CAPITAL MANAGEMENT, LLC $644,934,457 2,382,981 3.15% Shares
FARALLON CAPITAL MANAGEMENT, L.L.C. $602,175,451 2,218,366 2.94% Shares
NORGES BANK $496,243,717 1,828,122 2.42% Shares
FRED ALGER MANAGEMENT, LLC $467,285,974 1,721,444 2.28% Shares
Sofinnova Investments, Inc. $420,823,506 1,550,280 2.05% Shares
Capital World Investors $408,365,851 1,504,387 1.99% Shares
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $408,180,994 1,503,706 1.99% Shares
MAVERICK CAPITAL LTD $368,266,171 1,356,663 1.80% Shares
D. E. Shaw & Co., Inc. $322,096,327 1,186,577 1.57% Shares
GOLDMAN SACHS GROUP INC $311,099,616 1,146,066 1.52% Shares
Clearbridge Investments, LLC $276,424,438 1,018,325 1.35% Shares
RTW INVESTMENTS, LP $271,450,000 1,000,000 1.32% Shares
VANGUARD FIDUCIARY TRUST CO $249,356,413 918,609 1.22% Shares
WESTFIELD CAPITAL MANAGEMENT CO LP $197,243,187 726,628 0.96% Shares
ARK Investment Management LLC $186,989,592 688,855 0.91% Shares
Sumitomo Mitsui Trust Group, Inc. $174,716,892 643,643 0.85% Shares
Chevy Chase Trust Holdings, LLC $162,830,912 599,856 0.79% Shares
WORLDQUANT MILLENNIUM ADVISORS LLC $160,551,817 591,460 0.78% Shares
FIRST TRUST ADVISORS LP $138,768,953 511,214 0.68% Shares
GILDER GAGNON HOWE & CO LLC $135,199,396 498,064 0.66% Shares
AMERICAN CENTURY COMPANIES INC $129,951,802 478,732 0.63% Shares
VICTORY CAPITAL MANAGEMENT INC $125,949,543 463,988 0.61% Shares
Avala Global LP $124,867,000 460,000 0.61% Shares
JANE STREET GROUP, LLC $120,781,406 444,949 0.59% Shares
Robeco Institutional Asset Management B.V. $110,918,814 408,616 0.54% Shares
VIKING GLOBAL INVESTORS LP $106,053,886 390,694 0.52% Shares
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC $105,594,050 389,000 0.52% Shares
Driehaus Capital Management LLC $104,202,054 383,872 0.51% Shares
GOLDMAN SACHS GROUP INC $103,829,625 382,500 0.51% Call option
Swiss National Bank $103,096,710 379,800 0.50% Shares
JANE STREET GROUP, LLC $100,300,775 369,500 0.49% Put option
Amova Asset Management Americas, Inc. $99,926,238 368,066 0.49% Shares
Man Group plc $97,455,436 359,018 0.48% Shares
California Public Employees Retirement System $93,399,430 344,076 0.46% Shares
Squarepoint Ops LLC $91,279,949 336,268 0.45% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $84,486,098 311,240 0.41% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $82,819,395 305,100 0.40% Put option
DIMENSIONAL FUND ADVISORS LP $82,812,880 305,076 0.40% Shares
COATUE MANAGEMENT LLC $80,563,646 296,790 0.39% Shares
Capital Impact Advisors, LLC $80,411,091 296,228 0.39% Shares
AMERIPRISE FINANCIAL INC $75,314,616 277,451 0.37% Shares
ENVESTNET ASSET MANAGEMENT INC $74,936,546 276,064 0.37% Shares
CITADEL ADVISORS LLC $72,099,020 265,607 0.35% Shares
VANGUARD ASSET MANAGEMENT, Ltd $71,251,553 262,485 0.35% Shares
ORBIMED ADVISORS LLC $71,119,900 262,000 0.35% Shares
TWO SIGMA ADVISERS, LP $70,490,993 307,700 0.34% Shares
PRINCIPAL FINANCIAL GROUP INC $70,377,484 259,265 0.34% Shares
PointState Capital LP $70,037,357 258,012 0.34% Shares
Point72 Asset Management, L.P. $68,655,134 252,920 0.34% Shares
Assenagon Asset Management S.A. $68,098,390 250,869 0.33% Shares
BlackRock, Inc. $61,219,847 225,529 0.30% Shares
National Pension Service $61,139,769 225,234 0.30% Shares
ALLIANCEBERNSTEIN L.P. $58,410,679 292,068 0.29% Shares
TD Asset Management Inc $56,207,523 207,064 0.27% Shares
ZEVENBERGEN CAPITAL INVESTMENTS LLC $55,932,001 206,049 0.27% Shares
CITADEL ADVISORS LLC $54,561,450 201,000 0.27% Put option
Artemis Investment Management LLP $54,313,616 200,087 0.27% Shares
NEUBERGER BERMAN GROUP LLC $52,978,986 195,170 0.26% Shares
Mitsubishi UFJ Asset Management Co., Ltd. $50,424,281 185,759 0.25% Shares
BNP PARIBAS FINANCIAL MARKETS $49,380,284 181,913 0.24% Shares
Eversept Partners, LP $47,722,810 175,807 0.23% Shares
Erste Asset Management GmbH $47,112,625 173,011 0.23% Shares
FRONTIER CAPITAL MANAGEMENT CO LLC $47,109,261 173,547 0.23% Shares
RHUMBLINE ADVISERS $46,531,361 171,418 0.23% Shares
JENNISON ASSOCIATES LLC $46,107,586 169,857 0.23% Shares
TUDOR INVESTMENT CORP ET AL $45,830,804 168,837 0.22% Shares
LPL Financial LLC $45,315,137 166,937 0.22% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $44,300,640 163,200 0.22% Call option
Qube Research & Technologies Ltd $43,724,895 161,079 0.21% Shares
IEQ CAPITAL, LLC $40,419,133 148,901 0.20% Shares
Ensign Peak Advisors, Inc $39,971,827 147,253 0.20% Shares
JANE STREET GROUP, LLC $39,930,295 147,100 0.19% Call option
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $39,561,022 197,815 0.19% Shares
MILLENNIUM MANAGEMENT LLC $39,068,984 143,927 0.19% Shares
ROYAL BANK OF CANADA $38,963,000 143,535 0.19% Shares
PANAGORA ASSET MANAGEMENT INC $38,891,999 143,275 0.19% Shares
HighTower Advisors, LLC $38,255,720 140,931 0.19% Shares
Caption Management, LLC $38,003,000 140,000 0.19% Call option
BNP PARIBAS ASSET MANAGEMENT Holding S.A. $37,658,258 138,730 0.18% Shares
Rokos Capital Management LLP $37,210,859 137,049 0.18% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $36,308,609 133,758 0.18% Shares
RAYMOND JAMES FINANCIAL INC $35,775,481 131,794 0.17% Shares
MAPLELANE CAPITAL, LLC $34,338,425 126,500 0.17% Call option
CANADA PENSION PLAN INVESTMENT BOARD $33,741,235 124,300 0.16% Shares
BANK OF AMERICA CORP /DE/ $32,343,539 119,151 0.16% Shares
Davern Capital Partners, LP $32,295,764 118,975 0.16% Shares
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM $32,267,262 118,870 0.16% Shares
ThornTree Capital Partners LP $31,493,900 116,021 0.15% Shares
CITADEL ADVISORS LLC $30,918,155 113,900 0.15% Call option
MARSHALL WACE, LLP $30,550,069 112,544 0.15% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $30,538,398 112,501 0.15% Shares
UBS Group AG $29,990,339 110,482 0.15% Shares
Science & Technology Partners, L.P. $29,826,926 109,880 0.15% Shares
AVIVA PLC $29,381,205 108,238 0.14% Shares

Company insiders 21 insiders · 1 officers · 12 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Robert Alan Schueren Chief Operating Officer Oct. 7, 2020 M 52,855 0 0 $0
Rowan E Chapman Director July 15, 2026 S 4,663 0 2 $-679,637
Eric H Rubin Director June 26, 2026 A 2,204 0 0 $0
Monica Bertagnolli Director June 26, 2026 A 7,020 0 0 $0
Gail Boxer Marcus Director June 26, 2026 A 7,852 0 1 $-651,646
Roy D. Baynes Director June 26, 2026 A 20,158 0 0 $0
Thomas J. Lynch Jr. Director June 26, 2026 A 1,905 0 0 $0
Herm Rosenman Director June 26, 2026 A 5,927 0 5 $-15,143,996
ROELOF BOTHA ("RB") Director June 26, 2026 A 4,585 0 6 $-17,184,060
Dr. James I. Healy Director Dec. 13, 2023 S 0 0 0 $0
Todd C Cozzens Director June 12, 2020 A 7,278 0 0 $0
John Steuart Director May 16, 2019 M 7,278 0 0 $0
Edward C. Driscoll Jr. Director May 16, 2019 M 52,009 0 0 $0
Jonathan Sheena Aug. 10, 2026 S 230,464 0 41 $-7,235,616
Matthew Rabinowitz Aug. 7, 2026 S 2,000 0 25 $-23,012,521
Michael Burkes Brophy Aug. 4, 2026 S 51,637 0 7 $-1,498,665
John Fesko Aug. 3, 2026 S 183,774 0 3 $-519,299
Solomon Moshkevich Aug. 3, 2026 S 129,019 0 13 $-2,685,306
Daniel Rabinowitz Aug. 3, 2026 S 170,073 0 19 $-13,604,463
Steven Leonard Chapman Aug. 3, 2026 S 99,897 0 10 $-2,476,206
Ruth Williams Brinkley April 24, 2026 A 5,475 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 1 position

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Sofinnova Venture Partners VIII, L.P. (“SVP VIII”), Sofinnova Management VIII, L.L.C., Sofinnova Venture Partners IX, L.P. (“SVP IX”), Sofinnova Management IX, L.L.C., Dr. Michael F. Powell (“Powell”), Dr. James I. Healy ×3 filings Feb. 13, 2020 Initial filing Passive investment SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 103 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
GNOM · Global X Funds 4.15% 10,370 NS May 31, 2026 N-PORT
ARKG · ARK ETF Trust 4.07% 243,718 NS April 30, 2026 N-PORT
IBB · iShares Trust 2.79% 1,002,768 SH Aug. 8, 2026 Daily
MEDI · Harbor ETF Trust 2.35% 3,142 NS April 30, 2026 N-PORT
QQQJ · Invesco Exchange-Traded Fund Trust … 2.22% 81,682 SH Aug. 8, 2026 Daily
HTEC · EXCHANGE TRADED CONCEPTS TRUST 2.17% 5,611 NS April 30, 2026 N-PORT
MID · AMERICAN CENTURY ETF TRUST 1.72% 7,656 NS May 31, 2026 N-PORT
HFGO · Hartford Funds Exchange-Traded Trust 1.57% 13,843 NS April 30, 2026 N-PORT
FMED · Fidelity Covington Trust 1.43% 2,615 NS May 31, 2026 N-PORT
FXH · First Trust Exchange-Traded AlphaDE… 1.34% 56,770 NS April 30, 2026 N-PORT
ARKK · ARK ETF Trust 1.17% 369,404 NS April 30, 2026 N-PORT
GURU · Global X Funds 1.04% 2,954 NS April 30, 2026 N-PORT
IWP · iShares Trust 1.04% 789,272 SH Aug. 8, 2026 Daily
VBK · VANGUARD INDEX FUNDS 1.01% 1,802,288 SH Aug. 8, 2026 Daily
LABU · Direxion Shares ETF Trust 0.98% 24,696 NS April 30, 2026 N-PORT
TAX · EA Series Trust 0.92% 1,046 NS May 29, 2026 N-PORT
HQGO · Lattice Strategies Trust 0.68% 1,580 NS April 30, 2026 N-PORT
SXQG · EXCHANGE TRADED CONCEPTS TRUST 0.66% 1,989 NS May 31, 2026 N-PORT
TEXN · iShares Trust 0.63% 396 SH Aug. 8, 2026 Daily
SMLF · iShares Trust 0.60% 95,727 SH Aug. 8, 2026 Daily
IYH · iShares Trust 0.59% 81,823 SH Aug. 8, 2026 Daily
BBMC · J.P. Morgan Exchange-Traded Fund Tr… 0.56% 54,813 NS April 30, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.54% 404,713 SH Aug. 8, 2026 Daily
CANC · Tema ETF Trust 0.54% 4,238 NS May 31, 2026 N-PORT
CGMM · Capital Group Equity ETF Trust I 0.48% 60,571 NS May 31, 2026 N-PORT
IMCG · iShares Trust 0.48% 74,206 SH Aug. 8, 2026 Daily
FTC · First Trust Exchange-Traded AlphaDE… 0.48% 29,486 NS April 30, 2026 N-PORT
VXF · VANGUARD INDEX FUNDS 0.44% 1,643,356 SH Aug. 8, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.44% 3,120,454 SH Aug. 8, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.44% 60,581 NS April 30, 2026 N-PORT
LQAI · Exchange Listed Funds Trust 0.40% 41 NS April 30, 2026 N-PORT
ROUS · Lattice Strategies Trust 0.28% 8,068 NS April 30, 2026 N-PORT
IWR · iShares Trust 0.26% 555,978 SH Aug. 8, 2026 Daily
GSLC · Goldman Sachs ETF Trust 0.26% 178,926 NS May 31, 2026 N-PORT
SIZE · iShares Trust 0.25% 4,071 SH Aug. 8, 2026 Daily
IMCB · iShares Trust 0.25% 15,707 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.24% 21,798 SH Aug. 8, 2026 Daily
MMLG · First Trust Exchange-Traded Fund VI… 0.24% 1,020 NS May 31, 2026 N-PORT
EUSA · iShares, Inc. 0.24% 17,374 SH Aug. 8, 2026 Daily
FAD · First Trust Exchange-Traded AlphaDE… 0.24% 5,580 NS April 30, 2026 N-PORT
MMSC · First Trust Exchange-Traded Fund VI… 0.24% 558 NS May 31, 2026 N-PORT
JMOM · J.P. Morgan Exchange-Traded Fund Tr… 0.23% 23,988 NS April 30, 2026 N-PORT
AVIE · AMERICAN CENTURY ETF TRUST 0.22% 103 NS May 31, 2026 N-PORT
GINN · Goldman Sachs ETF Trust 0.22% 2,049 NS May 31, 2026 N-PORT
GSEW · Goldman Sachs ETF Trust 0.20% 15,978 NS May 31, 2026 N-PORT
FEX · First Trust Exchange-Traded AlphaDE… 0.17% 12,285 NS April 30, 2026 N-PORT
EQAL · Invesco Exchange-Traded Fund Trust … 0.13% 3,281 SH Aug. 8, 2026 Daily
GGUS · Goldman Sachs ETF Trust 0.11% 2,357 NS May 31, 2026 N-PORT
ILCG · iShares Trust 0.11% 13,472 SH Aug. 8, 2026 Daily
VONG · VANGUARD SCOTTSDALE FUNDS 0.11% 216,186 SH Aug. 8, 2026 Daily