APVO Aptevo Therapeutics Inc. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 14, 2026
$1.76
· of 52w range
· above low
· to high
$1.0052w low
$18.7252w high
Market Cap (MRQ)
$2M
P/E
-0.0
EPS
$-87.27
your badges
52W Range
$1–$19
Analyst Rating
BUY
Price Target
$26
P/E
-0.0
ROE
-217.2%
Net Profit Margin
·
Your badge strip is empty — pin a metric anywhere on this page.
APVO Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$1.76
Market Cap (MRQ)
$2M
P/E
-0.0
EPS
$-87.27
ROE
-217.2%
52W Range
$1–$19
APVO Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
range
bars
Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.
Stock splits
| Ex-date | Split | Type |
|---|---|---|
| Dec. 30, 2025 | 1-for-18 | Reverse |
| May 27, 2025 | 1-for-20 | Reverse |
| Dec. 4, 2024 | 1-for-37 | Reverse |
| March 6, 2024 | 1-for-44 | Reverse |
| March 27, 2020 | 1-for-14 | Reverse |
10-Year Performance Revenue, net income, margins and EPS trends
Revenue·2016-12-31 → 2022-12-31
EPS$-87.272021-12-31 → 2025-12-31
Free Cash Flow·2016-12-31 → 2022-12-31
Net margin·2016-12-31 → 2022-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | APVO | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -0.05Y avg ≈1179.2 | ≈1179.2 | · | · | |
| P/S | 0.15Y avg ≈53750.5 | ≈53750.5 | 13.0 | Undervalued | |
| P/B (MRQ) | 0.45Y avg ≈213755.0 | ≈213755.0 | 0.7 | Pricier | |
| Price / Cash Flow | -0.15Y avg ≈-18183.8 | ≈-18183.8 | · | · | |
| Price / Tangible Book | 0.15Y avg ≈213755.0 | ≈213755.0 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | APVO | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -121.4%5Y avg ≈-66.7% | ≈-66.7% | -125.6% | Top tier | |
| ROE | -217.2%5Y avg ≈-298.8% | ≈-298.8% | -217.2% | In line | |
| ROIC | -151.4% | · | · | · |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | APVO | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 2.15Y avg ≈2.6 | ≈2.6 | 2.2 | Low liquidity | |
| Quick Ratio | 3.65Y avg ≈2.2 | ≈2.2 | 1.9 | In line |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
-105.8%
Next Report
Nov 04, 2026
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| June 30, 2026 | Aug 14, 2026 | $-5.31 | $-6.14 | 13.5% |
| March 31, 2026 | May 12, 2026 | $-6.41 | $-5.71 | -12.2% |
| Dec. 31, 2025 | $-0.01 | $-8.25 | 99.9% | |
| Sept. 30, 2025 | $-33.48 | $-38.37 | 12.7% | |
| June 30, 2025 | $-151.20 | $-1527.55 | 90.1% | |
| March 31, 2025 | $-1580.40 | $-1545.91 | -2.2% | |
| Dec. 31, 2024 | $-29653.20 | $-2845.80 | -942.0% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | $3M | $12M | $4M | $32M | $23M | $15M | $10M | $34M | |
| Cost of Revenue | · | · | · | · | · | · | $20M | $11M | $5M | $12M | $17M | |
| R&D Expense | $15M | $14M | $17M | $18M | $19M | $18M | $25M | $35M | $29M | $29M | $35M | |
| SG&A Expense | $12M | $10M | $12M | $14M | $15M | $14M | $16M | $28M | $35M | $36M | $43M | |
| Operating Income | $-26M | $-25M | $-29M | $-29M | $-21M | $-27M | $-41M | $-52M | $-54M | $-139M | $-61M | |
| Other Non-op | $345.0K | $472.0K | $578.0K | $-4M | $-8M | $-1M | $-2M | $-2M | $-2M | $-810.0K | $-237.0K | |
| Pretax Income | $-26M | $-24M | $-19M | $7M | $-29M | $-31M | $-43M | $-54M | $-56M | $-140M | $-61M | |
| Income Tax | $0 | · | · | · | · | · | · | · | $-23M | $-20M | $-2M | |
| Net Income | $-26M | $-24M | $-17M | $8M | $-28M | $-18M | $-40M | $-54M | $7M | $-112M | $-59M | |
| EPS (Basic) | $-87.27 | $-31460.23 | $-2316.83 | $1.57 | $-6.07 | · | · | · | · | · | · | |
| EPS (Diluted) | $-87.27 | $-31460.23 | $-2316.83 | $1.57 | $-6.07 | · | · | · | · | · | · | |
| Shares (Basic) | 315,535 | 767 | 7,515 | 5,100,310 | 4,687,952 | · | · | · | · | · | · | |
| Shares (Diluted) | 315,535 | 767 | 7,515 | 5,102,914 | 4,687,952 | · | · | · | · | · | · | |
| EBITDA | $-26M | $-24M | $-28M | $-28M | $-20M | · | $-40M | $-49M | · | $-124M | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $22M | $9M | $17M | $23M | $45M | $40M | $12M | $31M | $7M | $10M | $5M | |
| Short-term Investments | · | · | · | · | · | · | · | · | $74M | $45M | · | |
| Receivables | · | · | · | · | · | · | $7M | $5M | $2M | $307.0K | $6M | |
| Inventory | · | · | · | · | · | · | $6M | $2M | $1M | $461.0K | $20M | |
| Prepaid Expense | $1M | $2M | $1M | $2M | $2M | $2M | $1M | $7M | $4M | $6M | $2M | |
| Other Current Assets | $853.0K | $1M | $689.0K | $744.0K | $780.0K | $133.0K | $160.0K | $4M | $7M | $2M | · | |
| Current Assets | $23M | $11M | $19M | $27M | $53M | $47M | $30M | $49M | $95M | $71M | $35M | |
| PP&E (Net) | $303.0K | $543.0K | $895.0K | $1M | $2M | $3M | $4M | $5M | $6M | $6M | $4M | |
| PP&E (Gross) | $14M | $14M | $14M | $14M | $15M | $14M | $14M | $14M | $13M | $13M | $10M | |
| Accum. Depreciation | $14M | $14M | $14M | $13M | $12M | $11M | $10M | $9M | $8M | $7M | $6M | |
| Goodwill | · | · | · | · | · | · | · | · | · | · | $29M | |
| Intangibles | · | · | · | · | · | · | $4M | $5M | $6M | $7M | · | |
| Other Non-current Assets | · | · | · | · | $68.0K | $746.0K | $757.0K | $905.0K | · | · | · | |
| Total Assets | $27M | $16M | $25M | $34M | $57M | $54M | $53M | $67M | $117M | $92M | $128M | |
| Accounts Payable | $877.0K | $1M | · | · | · | · | $6M | $12M | · | · | $10M | |
| Current Liabilities | $6M | $6M | $7M | $9M | $35M | $15M | $38M | $18M | $19M | $20M | $20M | |
| Capital Leases | $4M | $5M | $5M | $6M | $1M | $2M | $3M | · | · | · | · | |
| Deferred Tax | · | · | · | · | · | · | · | · | · | · | $16M | |
| Other Non-current Liabilities | · | $0 | · | · | · | · | · | $200.0K | $734.0K | $469.0K | $71.0K | |
| Total Liabilities | $10M | $11M | $13M | $16M | $55M | $37M | $42M | $37M | $35M | $41M | $39M | |
| Long-term Debt | · | · | $0 | $4M | $16M | $28M | · | · | $19M | · | · | |
| Total Debt | · | · | · | $3M | $12M | · | $20M | $19M | · | $18M | · | |
| Common Stock | $114.0K | $84.0K | $61.0K | $48.0K | $47.0K | $46.0K | $45.0K | $23.0K | $22.0K | $20.0K | · | |
| Retained Earnings | $-275M | $-248M | $-223M | $-206M | $-214M | $-186M | $-168M | $-127M | $-74M | $-81M | $-232M | |
| AOCI | · | · | · | · | · | · | · | · | $-105.0K | $-33.0K | · | |
| Stockholders' Equity | $17M | $5M | $12M | $18M | $1M | $17M | $12M | $30M | $82M | $51M | $89M | |
| Liabilities + Equity | $27M | $16M | $25M | $34M | $57M | $54M | $53M | $67M | $117M | $92M | $128M | |
| Shares Outstanding | 997,830 | 4,051 | 11,958 | 6,466,294 | 4,898,143 | 4,410,909 | 3,234,231 | 22,808,416 | 21,605,716 | 20,271,737 | 0 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $240.0K | $352.0K | $567.0K | $901.0K | $1M | $1M | $2M | $2M | $3M | $3M | $3M | |
| Stock-based Comp | $96.0K | $1M | $2M | $2M | $2M | $1M | $2M | $2M | $5M | $4M | $1M | |
| Deferred Tax | · | · | · | · | · | · | · | · | $-11M | $-15M | $-1M | |
| Amort. of Intangibles | · | · | · | · | · | · | $800.0K | $800.0K | $800.0K | $800.0K | $3M | |
| Other Non-cash | $39.0K | $-1M | $3M | $-32M | $4M | · | $-6M | $-2M | · | $84M | · | |
| Operating Cash Flow | $-26M | $-24M | $-12M | $-21M | $-22M | $-29M | $-42M | $-51M | $-42M | $-37M | $-49M | |
| CapEx | · | · | · | $29.0K | $713.0K | $88.0K | $153.0K | $976.0K | $1M | $3M | $2M | |
| Investing Cash Flow | $0 | $0 | $0 | $-29.0K | $-713.0K | $28M | $4M | $73M | $29M | · | · | |
| Debt Issued | · | · | · | · | · | · | · | · | · | $20M | · | |
| Net Debt Issued | · | $0 | $-3M | $-12M | $-11M | · | · | · | · | $20M | · | |
| Stock Issued | $38M | $10M | $6M | $7M | $10M | · | · | $623.0K | $442.0K | · | · | |
| Net Stock Activity | $38M | $10M | · | $7M | $10M | · | · | $623.0K | · | · | · | |
| Financing Cash Flow | $38M | $16M | $6M | $-3M | $26M | $24M | $20M | $-787.0K | $20M | · | · | |
| Net Change in Cash | $13M | $-8M | $-6M | $-24M | $4M | $23M | $-18M | $21M | $7M | $5M | $1M | |
| Taxes Paid | $0 | $0 | · | · | · | · | · | · | · | · | · | |
| Free Cash Flow | · | · | · | $-21M | $-22M | · | $-43M | $-52M | · | $-39M | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | -919.8% | -174.1% | · | -131.4% | -224.0% | · | -348.4% | · | |
| Net Margin | · | · | · | 257.8% | -231.5% | · | -124.8% | -232.8% | · | -308.5% | · | |
| Pretax Margin | · | · | · | 225.2% | -239.2% | · | -137.8% | -232.8% | · | -350.6% | · | |
| EBITDA Margin | · | · | · | -890.8% | -164.8% | · | -124.5% | -213.6% | · | -339.2% | · | |
| ROA | -121.4% | -119.4% | -59.0% | 17.7% | -51.7% | · | -66.9% | -58.2% | · | -99.8% | · | |
| ROE | -217.2% | -526.0% | -129.3% | 47.6% | -668.9% | · | -256.1% | -144.3% | · | -152.2% | · | |
| ROIC | -151.4% | · | · | · | · | · | · | · | · | -162.0% | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.8 | 1.7 | 2.6 | 3.2 | 1.5 | · | 0.8 | 2.8 | · | 3.7 | · | |
| Quick Ratio | 3.6 | 1.4 | 2.3 | 2.6 | 1.3 | · | 0.5 | 2.0 | · | 3.0 | · | |
| Debt / Equity | · | · | · | 0.2 | 9.6 | · | 1.7 | 0.6 | · | 0.4 | · | |
| LT Debt / Equity | · | · | · | 0.1 | · | · | · | 0.6 | · | 0.4 | · |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | 0.1 | 0.2 | · | 0.5 | 0.2 | · | 0.3 | · | |
| Inventory Turnover | · | · | · | · | · | · | 5.0 | · | · | 1.8 | · | |
| Receivables Turnover | · | · | · | · | · | · | 5.3 | 6.3 | · | 6.8 | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $17.42 | $3.26 | $0.63 | $2.78 | $0.25 | · | $0.26 | $1.33 | · | $2.49 | · | |
| Revenue / Share | · | · | · | $0.61 | · | · | · | · | · | · | · | |
| Cash Flow / Share | $-81.11 | $-86.13 | $-0.96 | $-4.12 | · | · | · | · | · | · | · | |
| Cash / Share | $21.67 | $5.97 | $0.87 | $3.50 | $9.20 | · | $0.27 | $1.34 | · | $0.48 | · | |
| EPS (TTM) | $-87.27 | $-31460.23 | $-2316.83 | $1.57 | $-6.07 | · | · | · | · | · | · |
Growth Rates
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | · | -74.7% | 185.3% | · | · | · | · | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $12M | $12M | $12M | $3M | $12M | $4M | $32M | $23M | $15M | $10M | · | |
| Net Income TTM | $-26M | $-24M | $-17M | $8M | $-28M | $-18M | $-40M | $-54M | $7M | $-112M | · | |
| Market Cap | $9M | $126M | $114.73B | $488.46B | $1.26T | · | $13.52T | $13.20T | · | $22.55T | · | |
| Enterprise Value | · | · | · | $488.44B | $1.26T | · | $13.52T | $13.20T | · | $22.55T | · | |
| P/E | -0.1 | -0.0 | -2.5 | 48114.1 | -42215.4 | · | · | · | · | · | · | |
| P/S | 0.8 | 10.7 | 9772.0 | 156858.9 | 102109.9 | · | 416952.2 | 572427.1 | · | 2258110.4 | · | |
| P/B | 0.5 | 26.4 | 9388.2 | 27175.8 | 1032183.8 | · | 1141636.4 | 434262.2 | · | 445897.1 | · | |
| P / Tangible Book | 0.5 | 26.4 | 9388.2 | 27175.8 | 1032183.8 | 317201.6 | · | · | · | · | · | |
| P / Cash Flow | -0.4 | -5.3 | -9781.2 | -23235.6 | -57896.4 | · | -318978.3 | -256780.7 | · | -611666.0 | · | |
| P / FCF | · | · | · | -23203.6 | -56052.9 | · | -317831.0 | -251997.7 | · | -572642.7 | · | |
| EV / EBITDA | · | · | · | -17607.8 | -61962.0 | · | -334958.7 | -267968.8 | · | -182445.8 | · | |
| EV / FCF | · | · | · | -23202.7 | -56051.4 | · | -317831.2 | -251997.5 | · | -572641.7 | · | |
| EV / Revenue | · | · | · | 156852.8 | 102107.2 | · | 416952.4 | 572426.6 | · | 2258106.7 | · | |
| Earnings Yield | -925.5% | -36496.8% | -39.3% | 0.00% | 0.00% | · | · | · | · | · | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | |
| R&D Expense | $4M | $4M | $4M | $4M | $3M | $4M | $4M | $3M | $4M | $4M | $4M | $4M | $5M | $4M | $5M | $4M | |
| SG&A Expense | $3M | $3M | $2M | $4M | $3M | $3M | $3M | $2M | $2M | $3M | $3M | $3M | $3M | $4M | $3M | $3M | |
| Operating Income | $-6M | $-7M | $-6M | $-8M | $-6M | $-6M | $-6M | $-5M | $-6M | $-7M | $-6M | $-7M | $-8M | $-8M | $-8M | $-8M | |
| Other Non-op | $87.0K | $140.0K | $190.0K | $61.0K | $22.0K | $72.0K | $70.0K | $112.0K | $141.0K | $149.0K | $188.0K | $227.0K | $230.0K | $-67.0K | $21.0K | $-25.0K | |
| Net Income | $-6M | $-7M | $-6M | $-8M | $-6M | $-6M | $-6M | $-5M | $-6M | $-7M | $-6M | $-6M | $-8M | $3M | $-5M | $-8M | |
| EPS (Basic) | $-5.31 | $-6.41 | $-72.25 | $-2.23 | $-151.29 | $-1581.81 | $-29497.20 | $-357.86 | $-1236.96 | $-368.21 | $-2258.10 | $-22.16 | $-53.95 | $17.38 | $-0.96 | $-1.50 | |
| EPS (Diluted) | $-5.31 | $-6.41 | $-72.25 | $-2.23 | $-151.29 | $-1581.81 | $-29497.20 | $-357.86 | $-1236.96 | $-368.21 | $-2258.10 | $-22.16 | $-53.95 | $17.38 | $-0.96 | $-1.50 | |
| Shares (Basic) | 1,196,364 | 1,060,678 | · | 4,049,046 | 41,008 | 4,051 | · | 14,254 | 4,756 | 18,560 | · | 285,886 | 147,321 | 159,597 | · | 5,090,592 | |
| Shares (Diluted) | 1,196,364 | 1,060,678 | · | 4,049,046 | 41,008 | 4,051 | · | 14,254 | 4,756 | 18,560 | · | 285,886 | 147,321 | 159,597 | · | 5,090,592 | |
| EBITDA | $-6M | · | · | $-8M | $-6M | $-6M | · | $-5M | $-6M | $-7M | · | $-7M | $-8M | $-8M | · | $-8M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $10M | $15M | $22M | $21M | $9M | $2M | $9M | $8M | $8M | $10M | $17M | $19M | $21M | $25M | $23M | $22M | |
| Prepaid Expense | $1M | $1M | $1M | $2M | $2M | $1M | $2M | $2M | $798.0K | $1M | $1M | $1M | $910.0K | $2M | $2M | $1M | |
| Other Current Assets | $462.0K | $851.0K | $853.0K | $77.0K | $82.0K | $120.0K | $1M | $624.0K | $715.0K | $691.0K | $689.0K | $649.0K | $764.0K | $2M | $744.0K | $658.0K | |
| Current Assets | $11M | $16M | $23M | $23M | $11M | $4M | $11M | $10M | $10M | $12M | $19M | $21M | $23M | $28M | $27M | $25M | |
| PP&E (Net) | $236.0K | $268.0K | $303.0K | $384.0K | $432.0K | $482.0K | $543.0K | $614.0K | $697.0K | $789.0K | $895.0K | $1M | $1M | $1M | $1M | $2M | |
| PP&E (Gross) | · | · | $14M | · | · | · | $14M | · | · | · | $14M | · | · | · | $14M | · | |
| Accum. Depreciation | · | · | $14M | · | · | · | $14M | · | · | · | $14M | · | · | · | $13M | · | |
| Total Assets | $15M | $20M | $27M | $27M | $16M | $8M | $16M | $15M | $15M | $18M | $25M | $27M | $29M | $35M | $34M | $32M | |
| Accounts Payable | $1M | $890.0K | $877.0K | · | · | · | $1M | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $5M | $5M | $6M | $6M | $5M | $5M | $6M | $6M | $5M | $6M | $7M | $7M | $7M | $6M | $9M | $8M | |
| Capital Leases | $3M | $4M | $4M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | $5M | $6M | $6M | $6M | $6M | $6M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | $14.0K | $14.0K | $14.0K | · | · | · | · | · | · | |
| Total Liabilities | $8M | $8M | $10M | $10M | $9M | $10M | $11M | $11M | $10M | $12M | $13M | $12M | $13M | $12M | $16M | $16M | |
| Long-term Debt | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | $3M | $4M | |
| Total Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $4M | |
| Common Stock | $114.0K | $114.0K | $114.0K | $110.0K | $99.0K | $84.0K | $84.0K | $82.0K | $69.0K | $66.0K | $61.0K | $56.0K | $49.0K | $49.0K | $48.0K | $47.0K | |
| Retained Earnings | $-288M | $-282M | $-275M | $-269M | $-260M | $-254M | $-248M | $-241M | $-236M | $-230M | $-223M | $-218M | $-211M | $-203M | $-206M | $-201M | |
| Stockholders' Equity | $6M | $12M | $17M | $17M | $7M | $-1M | $5M | $4M | $4M | $6M | $12M | $15M | $16M | $23M | $18M | $16M | |
| Liabilities + Equity | $15M | $20M | $27M | $27M | $16M | $8M | $16M | $15M | $15M | $18M | $25M | $27M | $29M | $35M | $34M | $32M | |
| Shares Outstanding | 1,418,952 | 1,203,753 | 997,830 | 13,808,966 | 3,224,156 | 1,458,504 | 4,051 | 17,050,536 | 4,080,665 | 673,430 | 11,958 | 14,465,703 | 7,543,440 | 7,239,471 | 6,466,294 | 5,090,644 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $32.0K | $35.0K | $81.0K | $49.0K | $49.0K | $61.0K | $71.0K | $84.0K | $91.0K | $106.0K | $116.0K | $123.0K | $150.0K | $178.0K | $161.0K | $222.0K | |
| Stock-based Comp | $58.0K | $57.0K | $2.0K | $77.0K | $-163.0K | $180.0K | $-72.0K | $149.0K | $273.0K | $719.0K | $358.0K | $455.0K | $465.0K | $915.0K | $357.0K | $359.0K | |
| Other Non-cash | · | · | · | · | · | $-408.0K | · | · | · | $-642.0K | · | · | · | $700.0K | · | · | |
| Operating Cash Flow | $-5M | $-8M | $-5M | $-7M | $-7M | $-7M | $-6M | $-5M | $-6M | $-7M | $-5M | $-6M | $-5M | $5M | $-6M | $-7M | |
| CapEx | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | $4.0K | |
| Investing Cash Flow | $0 | $0 | · | · | $0 | $0 | · | · | · | · | · | · | · | · | $0 | $-4.0K | |
| Net Debt Issued | · | · | · | · | · | · | · | · | · | · | · | · | · | $-3M | · | · | |
| Stock Issued | $726.0K | $872.0K | $32M | $-9M | $14M | $0 | · | $6M | · | · | $3M | $1M | $481.0K | $2M | · | $0 | |
| Net Stock Activity | · | · | · | · | · | · | · | $6M | · | · | · | · | · | $2M | · | · | |
| Financing Cash Flow | $726.0K | $871.0K | $6M | $18M | $14M | $0 | $7M | $5M | $4M | $-3.0K | $3M | $4M | $481.0K | $-2M | $6M | $-500.0K | |
| Net Change in Cash | $-5M | $-7M | $558.0K | $12M | $7M | $-7M | $961.0K | $-313.0K | $-2M | $-7M | $-2M | $-2M | $-4M | $3M | $59.0K | $-7M |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -42.2% | · | · | -35.8% | -40.6% | -49.4% | · | -24.1% | -26.8% | -26.0% | · | -21.5% | -23.5% | 6.9% | · | -16.0% | |
| ROE | -101.2% | · | · | -69.2% | -112.9% | -276.8% | · | -53.3% | -56.8% | -46.6% | · | -41.6% | -40.5% | 31.9% | · | -66.3% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.1 | · | · | 4.0 | 2.3 | 0.7 | · | 1.7 | 1.8 | 1.9 | · | 3.1 | 3.3 | 4.9 | · | 3.2 | |
| Quick Ratio | 1.9 | · | · | 3.8 | 1.9 | 0.4 | · | 1.3 | 1.5 | 1.6 | · | 2.8 | 3.0 | 4.4 | · | 2.8 | |
| Debt / Equity | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.2 | |
| LT Debt / Equity | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.1 |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $4.26 | · | · | $1.26 | $2.02 | $-1.01 | · | $0.26 | $1.09 | $9.06 | · | $1.02 | $2.15 | $3.21 | · | $3.10 | |
| Cash Flow / Share | · | · | · | · | · | $-4.51 | · | · | · | $-9.69 | · | · | · | $0.65 | · | · | |
| Cash / Share | $6.90 | · | · | $1.53 | $2.92 | $1.47 | · | $0.45 | $1.98 | $15.22 | · | $1.32 | $2.78 | $3.50 | · | $4.35 | |
| EPS (TTM) | $-86.20 | $-1598.85 | · | $-31232.53 | $-31588.16 | $-32673.83 | · | $-4221.13 | $-3885.43 | $-2702.42 | · | $-59.69 | $-39.03 | $20.50 | · | $1.26 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $3M | $12M | · | $3M | $3M | $3M | · | $3M | $3M | $3M | · | $3M | $3M | $3M | · | $7M | |
| Net Income TTM | $-26M | $-27M | · | $-26M | $-24M | $-24M | · | $-24M | $-25M | $-27M | · | $-16M | $-17M | $18M | · | $6M | |
| Market Cap | $6M | · | · | $20M | $10M | $34M | · | $2.27B | $924M | $2.34B | · | $155.43B | $358.60B | $479.68B | · | $503.88B | |
| Enterprise Value | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $503.87B | |
| P/E | -0.1 | -0.0 | · | 0.0 | -0.0 | -0.0 | · | -0.0 | -0.1 | -1.3 | · | -180.0 | -1218.0 | 3232.2 | · | 78557.5 | |
| P/S | 2.0 | · | · | 6.4 | 3.2 | 10.9 | · | 729.3 | 296.7 | 750.5 | · | 49913.6 | 115156.4 | 154041.3 | · | 74330.2 | |
| P/B | 1.0 | · | · | 1.2 | 1.5 | -23.0 | · | 513.8 | 207.0 | 383.0 | · | 10560.6 | 22063.4 | 20626.3 | · | 31968.3 | |
| P / Tangible Book | 1.0 | 0.4 | · | 1.2 | 1.5 | · | · | 513.8 | 207.0 | 383.0 | · | 10560.6 | 22063.4 | 20626.3 | · | 31968.3 | |
| P / Cash Flow | · | · | · | · | · | -5.1 | · | · | · | -351.4 | · | · | · | 105055.7 | · | · | |
| EV / Revenue | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 74327.5 | |
| Earnings Yield | -1941.4% | -37443.8% | · | -2153967.6% | -1035677.4% | -140835.5% | · | -3169.0% | -1715.9% | -77.9% | · | -0.56% | -0.08% | 0.03% | · | 0.00% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Revenue | · | · | · | $3M | $12M |
| Operating Margin % | · | · | · | -919.8% | -174.1% |
| Net Income | $-26M | $-24M | $-17M | $8M | $-28M |
| Diluted EPS | $-87.27 | $-31460.23 | $-2316.83 | $1.57 | $-6.07 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Debt / Equity | · | · | · | 0.2 | 9.6 |
| Current Ratio | 3.8 | 1.7 | 2.6 | 3.2 | 1.5 |
| Quick Ratio | 3.6 | 1.4 | 2.3 | 2.6 | 1.3 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Free Cash Flow | · | · | · | $-21M | $-22M |
Institutional owners (13F) 11 filers · $287K total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
11
Value held
$287K
New positions
1
Exited positions
0
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 1 (-3 vs prior Q) | 0 (-4 vs prior Q) | 1 (-1 vs prior Q) | 2 (+1 vs prior Q) | -3K |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| VANGUARD GROUP INC | $158,952 | 16,856 | 55.30% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $56,446 | 12,713 | 19.64% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $48,044 | 10,821 | 16.72% | Shares |
| VANGUARD FIDUCIARY TRUST CO | $18,390 | 4,142 | 6.40% | Shares |
| UBS Group AG | $3,242 | 730 | 1.13% | Shares |
| OSAIC HOLDINGS, INC. | $1,596 | 360 | 0.56% | Shares |
| SBI Securities Co., Ltd. | $484 | 109 | 0.17% | Shares |
| BARCLAYS PLC | $138 | 31 | 0.05% | Shares |
| GSA CAPITAL PARTNERS LLP | $96 | 21,539 | 0.03% | Shares |
| CWM, LLC | $21 | 5 | 0.01% | Shares |
| DANSKE BANK A/S | $4 | 1 | 0.00% | Shares |
Activists & 5%+ owners 2 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Tang Capital Partners, LP, Tang Capital Management, LLC, Kevin Tang ×6 filings | Nov. 26, 2021 | · | Initial filing | · | SEC |
| Undisclosed reporting person | Aug. 3, 2016 | · | Initial filing | · | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 17 insiders · 5 officers · 1 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Jane A Gross | SVP & Chief Scientific Officer | Jan. 29, 2021 A | 109,583 | 0 | 0 | $0 |
| Randy Joe Maddux | SVP of Operations, CMO | July 27, 2020 A | 75,000 | 0 | 0 | $0 |
| Michael Adelman | SVP, Commercial Operations | Feb. 18, 2020 A | 70,426 | 0 | 0 | $0 |
| Shawnte Mitchell | SVP, GC and Corporate Affairs | Feb. 18, 2020 A | 80,527 | 0 | 0 | $0 |
| Scott C Stromatt | Chief Medical Officer and SVP | March 1, 2019 M | 216,183 | 0 | 0 | $0 |
| Fuad El-Hibri | Director | Dec. 3, 2021 J | 7,373 | 0 | 0 | $0 |
| Emergent BioSolutions Inc. | 10% owner | Aug. 1, 2016 J | 0 | 0 | 0 | $0 |
| Soyoung Kwon | · | Aug. 6, 2026 M | 638 | 0 | 0 | $0 |
| Dirk Huebner | · | Aug. 6, 2026 M | 482 | 0 | 0 | $0 |
| Barbara Lopez Kunz | · | Aug. 6, 2026 M | 400 | 0 | 0 | $0 |
| Jeffrey G. Lamothe | · | Aug. 6, 2026 M | 961 | 0 | 0 | $0 |
| Grady Grant III | · | Aug. 6, 2026 M | 1,150 | 1 | 0 | $20,134 |
| John Niederhuber | · | Aug. 6, 2026 M | 400 | 0 | 0 | $0 |
| Marvin L White | · | Aug. 6, 2026 M | 1,261 | 0 | 0 | $0 |
| Daphne Taylor | · | Aug. 6, 2026 M | 638 | 0 | 0 | $0 |
| Daniel Abdun-Nabi | · | Aug. 6, 2026 M | 400 | 0 | 0 | $0 |
| Zsolt Harsanyi | · | Aug. 6, 2026 M | 400 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 1 ETF
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| VXF · VANGUARD INDEX FUNDS | 0.00% | 12,713 SH | Aug. 19, 2026 | Daily |
APVO Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 7 analysts
BUY
Median target
$25.50
+1348.9%
2 28.6%
Strong Buy
4 57.1%
Buy
1 14.3%
Hold
0 0.0%
Sell
0 0.0%
Strong Sell
12-Month Price Target
2 analysts · 2026-09-30Mean target $25.50 +1348.9%
← Below all targets
Current price $1.76
Low$21.00
Mean$25.50
High$30.00
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| APVO | $9M | -0.1 | · | · | -217.2% | · |
| MBIO | · | -2.5 | · | · | -30.9% | · |
| VIVS | $4M | -0.3 | -9.0% | -10567.2% | -294.8% | · |
| ADTX | $343.6K | -0.0 | -97.6% | -1349028.2% | -1183.4% | 8.4% |
| GOVX | $296.2K | · | -37.1% | -862.3% | -645.9% | · |
| ONCO | $2M | -0.1 | -67.7% | -1721.0% | -129.5% | 77.6% |
| REVB | · | · | · | · | · | · |
| DCOY | · | -0.0 | · | · | · | · |
| BRTX | $10M | -0.7 | -10.3% | -3959.4% | -547.6% | 93.4% |
| SBFM | · | · | · | · | · | · |
| BCAB | · | -0.6 | · | · | · | · |
My Metrics Your personal watchlist — selected rows from Full Fundamentals
Pick the metrics that matter to you — click the + next to any row in Full Fundamentals above.
Your selection is saved and follows you across all tickers.
Source: SEC 10-Q filed Aug 14, 2026