ENSC Ensysce Biosciences, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$0.38
Price · Aug 19, 2026
Fundamentals as of Aug 13, 2026

ENSC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$0.38
Market Cap
$2M
P/E (TTM)
-0.1
EPS (TTM)
$-3.98
Revenue (TTM)
$5M
Div Yield
ROE
-294.0%
Debt/Equity
0.1
52W Range
$0 – $3

ENSC Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $5M
6-point trend, +28.9%
2020-12-31 2025-12-31
EPS $-3.98
6-point trend, -3.98
2020-12-31 2025-12-31
Free Cash Flow $-8M
2025-12-31 2025-12-31
Margins -200.9%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ENSC
Peer Median
P/E (TTM)
5-point trend, +100.0%
-0.1
P/S (TTM)
5-point trend, -100.0%
0.3
2.4
P/B
5-point trend, +100.0%
0.5
1.0
EV / EBITDA
5-point trend, +100.0%
0.2
Price / FCF
-0.2

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ENSC
Peer Median
Operating Margin
5-point trend, +64.1%
-202.1%
Net Profit Margin
5-point trend, +75.7%
-200.9%
-313.2%
ROA
5-point trend, +55.1%
-156.0%
-105.1%
ROE
5-point trend, -172.2%
-294.0%
-142.1%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ENSC
Peer Median
Debt / Equity
5-point trend, +105.9%
0.1
0.0
Current Ratio
5-point trend, +66.9%
1.6
1.6
Quick Ratio
5-point trend, +26.8%
0.9

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ENSC
Peer Median
Revenue YoY
5-point trend, +43.5%
-2.8%
Revenue CAGR 3Y
5-point trend, +43.5%
26.2%
Revenue CAGR 5Y
5-point trend, +43.5%
5.2%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ENSC
Peer Median
EPS (Diluted)
5-point trend, -168.9%
$-3.98

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ENSC
Peer Median

ENSC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 7 analysts
  • Strong Buy 2 28.6%
  • Buy 4 57.1%
  • Hold 1 14.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

1 analysts · 2026-08-18
Median target $8.25 +2100.0%
Mean target $8.25 +2100.0%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.39%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.52 $-0.74 0.22%
Dec. 31, 2025 $-0.75 $-1.29 0.54%
Sept. 30, 2025 $-1.29 $-0.88 -0.41%
June 30, 2025 $-0.79 $-1.20 0.41%
March 31, 2025 $-1.39 $-3.08 1.7%
Dec. 31, 2024 $-2.90 $-2.79 -0.11%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ENSC $4M -0.2 -2.8% -200.9% -294.0%
ALZN $5M -0.4 -598.1%
FBLG -0.5
ERNA
BOLT $11M -0.3 0.07% -433.7% -102.2%
CDIO
ACXP $6M -0.5 -180.3%
PMCB $8M -0.3 -56.7%
BRTX $10M -0.7 -10.3% -3959.4% -547.6% 93.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for ENSC
Metric Trend 202520242023202220212020
Revenue 6-point trend, +28.9% $5M $5M $2M $3M $4M $4M
R&D Expense 6-point trend, +136.4% $10M $7M $8M $20M $5M $4M
SG&A Expense 6-point trend, +326.9% $5M $5M $5M $7M $19M $1M
Operating Expenses 6-point trend, +176.1% $15M $12M $13M $27M $23M $6M
Operating Income 6-point trend, -534.8% $-10M $-7M $-11M $-24M $-20M $-2M
Interest Expense 4-point trend, -64.4% · · $353.9K $109.5K $1M $995.5K
Interest Income · · · · · $719.6K
Other Non-op 5-point trend, +126.0% $73.4K $17.3K $15.4K $86.2K $-282.3K ·
Pretax Income · · · · · $5M
Net Income 6-point trend, -6225.5% $-10M $-8M $-11M $-24M $-29M $-160.9K
EPS (Basic) 6-point trend, -3.98 $-3.98 $-11.45 $-70.40 $-139.42 $-29.64 $0.00
EPS (Diluted) 6-point trend, -3.98 $-3.98 $-11.45 $-70.40 $-139.42 $-1.48 $0.00
Shares (Basic) 6-point trend, -83.8% 2,557,377 697,686 150,937 179,925 1,008,227 15,768,725
Shares (Diluted) 6-point trend, -84.5% 2,557,377 697,686 150,937 179,925 20,164,503 16,507,387
EBITDA 6-point trend, -648.1% $-10M $-7M $-11M $-24M $-20M $-1M
Balance Sheet 19
Annual Balance Sheet data for ENSC
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, +2119.4% $4M $4M $1M $3M $12M $194.2K
Prepaid Expense 6-point trend, +1496.6% $3M $2M $1M $2M $3M $157.5K
Other Current Assets 3-point trend, +14.2% $20.6K $18.0K $18.0K · · ·
Current Assets 6-point trend, +1982.6% $7M $5M $2M $5M $16M $347.9K
PP&E (Net) 2-point trend, +82104.6% $124.1K · · · · $151
Other Non-current Assets 6-point trend, +2104.6% $83.3K $252.6K $419.2K $585.9K $754.8K $3.8K
Total Assets 6-point trend, +2018.3% $7M $6M $3M $6M $16M $351.8K
Accounts Payable 6-point trend, +89.5% $3M $1M $2M $3M $301.1K $2M
Short-term Debt 6-point trend, -92.8% $306.7K $301.7K $854.7K $4M $13M $4M
Current Liabilities 6-point trend, -34.8% $5M $2M $3M $9M $16M $7M
Other Non-current Liabilities 4-point trend, -99.7% · $10.1K $26.4K $310.3K $4M ·
Total Liabilities 6-point trend, -34.8% $5M $2M $3M $10M $25M $7M
Total Debt 5-point trend, -97.6% $306.7K $301.7K $854.7K $4M $13M ·
Common Stock 6-point trend, -70.9% $459 $136 $21 $53 $124 $1.6K
Paid-in Capital 6-point trend, +188.7% $143M $133M $121M $107M $78M $50M
Retained Earnings 6-point trend, -149.7% $-140M $-130M $-122M $-111M $-86M $-56M
Stockholders' Equity 6-point trend, +149.9% $3M $4M $-322.9K $-4M $-8M $-6M
Liabilities + Equity 6-point trend, +2018.3% $7M $6M $3M $6M $16M $351.8K
Shares Outstanding 6-point trend, -71.0% 4,574,977 1,355,773 209,739 534,490 1,232,160 15,768,725
Cash Flow 11
Annual Cash Flow data for ENSC
Metric Trend 202520242023202220212020
Stock-based Comp 6-point trend, -0.9% $177.1K $110.7K $879.2K $1M $121.8K $178.7K
Operating Cash Flow 6-point trend, -525.8% $-8M $-8M $-11M $-18M $-8M $-1M
CapEx $123.6K · · · · ·
Investing Cash Flow 3-point trend, -100.1% $-123.6K · · $4.5K · $183M
Stock Issued · · · · $7M ·
Stock Repurchased · · · · · $185M
Net Stock Activity 2-point trend, +103.6% · · · · $7M $-185M
Financing Cash Flow 6-point trend, +694.4% $9M $10M $9M $9M $20M $1M
Net Change in Cash 6-point trend, +648.6% $808.3K $2M $-2M $-9M $12M $-147.3K
Taxes Paid 6-point trend, +56.2% $2.5K $3.2K $3.2K $1.6K $1.6K $1.6K
Free Cash Flow $-8M · · · · ·
Profitability 5
Annual Profitability data for ENSC
Metric Trend 202520242023202220212020
Operating Margin 5-point trend, +64.1% -202.1% -129.2% -480.5% -959.9% -562.7% ·
Net Margin 5-point trend, +75.7% -200.9% -153.3% -476.4% -959.3% -825.4% ·
EBITDA Margin 5-point trend, +64.1% -202.1% -129.2% -480.5% -959.9% -562.7% ·
ROA 5-point trend, +55.1% -156.0% -192.3% -247.3% -217.1% -347.6% ·
ROE 5-point trend, -172.2% -294.0% -471.8% 526.4% 417.6% 407.1% ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for ENSC
Metric Trend 202520242023202220212020
Current Ratio 5-point trend, +66.9% 1.6 2.4 0.7 0.6 1.0 ·
Quick Ratio 5-point trend, +26.8% 0.9 1.6 0.3 0.3 0.7 ·
Debt / Equity 5-point trend, +105.9% 0.1 0.1 -2.6 -1.1 -1.6 ·
Interest Coverage 3-point trend, -97.4% · · -30.3 -221.2 -15.3 ·
Efficiency 1
Annual Efficiency data for ENSC
Metric Trend 202520242023202220212020
Asset Turnover 5-point trend, +84.4% 0.8 1.3 0.5 0.2 0.4 ·
Per Share 5
Annual Per Share data for ENSC
Metric Trend 202520242023202220212020
Book Value / Share 5-point trend, +319.7% $0.70 $2.74 $-0.10 $-0.58 $-0.32 ·
Revenue / Share 4-point trend, +1031.5% $1.98 $7.47 $0.99 · $0.18 ·
Cash Flow / Share 4-point trend, -646.9% $-3.05 $-10.75 $-4.76 · $-0.41 ·
Cash / Share 5-point trend, +89.3% $0.94 $2.58 $0.36 $0.49 $0.50 ·
EPS (TTM) 6-point trend, -3.98 $-3.98 $-11.45 $-70.40 $-139.42 $-1.48 $0.00
Growth Rates 3
Annual Growth Rates data for ENSC
Metric Trend 202520242023202220212020
Revenue YoY 5-point trend, +73.0% -2.8% 133.6% -11.6% -28.5% -10.2% ·
Revenue CAGR 3Y 3-point trend, +252.0% 26.2% 13.8% -17.2% · · ·
Revenue CAGR 5Y 5.2% · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for ENSC
Metric Trend 202520242023202220212020
Revenue TTM 6-point trend, +28.9% $5M $5M $2M $3M $4M $4M
Net Income TTM 6-point trend, -6225.5% $-10M $-8M $-11M $-24M $-29M $-160.9K
Market Cap 5-point trend, -100.0% $4M $11M $50M $866M $416.96B ·
Enterprise Value 5-point trend, -100.0% $205.3K $8M $50M $867M $416.96B ·
P/E 5-point trend, +100.0% -0.2 -0.7 -0.2 -1.0 -11432.4 ·
P/S 5-point trend, -100.0% 0.8 2.1 22.4 343.2 118079.5 ·
P/B 5-point trend, +100.0% 1.3 3.0 -154.9 -233.1 -52925.8 ·
P / Tangible Book 2-point trend, -56.0% 1.3 3.0 · · · ·
P / Cash Flow 5-point trend, +100.0% -0.5 -1.5 -4.6 -48.4 -50588.8 ·
P / FCF -0.5 · · · · ·
EV / EBITDA 5-point trend, +100.0% -0.0 -1.2 -4.6 -35.8 -20984.1 ·
EV / FCF -0.0 · · · · ·
EV / Revenue 5-point trend, -100.0% 0.0 1.5 22.3 343.6 118079.6 ·
Earnings Yield 6-point trend, -4.33 -432.6% -140.7% -442.8% -103.3% -0.01% 0.00%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $5M$5M$2M$3M$4M
Operating Margin % -202.1%-129.2%-480.5%-959.9%-562.7%
Net Income $-10M$-8M$-11M$-24M$-29M
Diluted EPS $-3.98$-11.45$-70.40$-139.42$-1.48
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.10.1-2.6-1.1-1.6
Current Ratio 1.62.40.70.61.0
Quick Ratio 0.91.60.30.30.7
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-8M

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Institutional owners (13F) 19 filers · $187K total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
6 (+2 vs prior Q) 1 (-5 vs prior Q) 5 (0 vs prior Q) 1 (+1 vs prior Q) +313K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
ADAGE CAPITAL PARTNERS GP, L.L.C. $43,416 149,711 23.23% Shares
PERCEPTIVE ADVISORS LLC $25,133 86,666 13.44% Shares
CITADEL ADVISORS LLC $24,996 86,193 13.37% Shares
XTX Topco Ltd $22,331 77,005 11.95% Shares
JANE STREET GROUP, LLC $17,906 61,746 9.58% Shares
GEODE CAPITAL MANAGEMENT, LLC $17,697 61,027 9.47% Shares
VANGUARD GROUP INC $11,826 12,854 6.33% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $9,941 34,280 5.32% Shares
TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC $3,770 13,000 2.02% Shares
TWO SIGMA SECURITIES, LLC $3,756 12,953 2.01% Shares
VANGUARD CAPITAL MANAGEMENT LLC $3,728 12,854 1.99% Shares
Tower Research Capital LLC (TRC) $1,767 6,094 0.95% Shares
BARCLAYS PLC $418 1,440 0.22% Shares
SBI Securities Co., Ltd. $186 641 0.10% Shares
Virtu Financial LLC $28 95,391 0.01% Shares
BlackRock, Inc. $19 65 0.01% Shares
HRT FINANCIAL LP $15 54,429 0.01% Shares
FNY Investment Advisers, LLC $0 3,000 0.00% Shares
Clear Street Group Inc. $0 1 0.00% Shares

Company insiders 11 insiders · 2 officers · 1 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
George Peng Chief Financial Officer Dec. 5, 2017 J 100,265 0 0 $0
Eric Carrera Senior Vice President Dec. 5, 2017 J 63,031 0 0 $0
Bob G Gower Director April 23, 2026 C 916,740 2 0 $444,135
MORGAN STANLEY 10% owner June 19, 2020 S 0 0 0 $0
HG Vora Capital Management, LLC 10% owner Dec. 5, 2017 J 2,837,500 0 0 $0
Richard Chester Wright June 30, 2021 A 0 0 $0
Andrew Benton June 30, 2021 A 0 0 $0
Kevin Geoffrey Birkett June 30, 2021 A 0 0 $0
Lynn Kirkpatrick June 30, 2021 A 284,851 0 0 $0
Steven Robert Martin June 30, 2021 A 0 0 $0
William K Schmidt June 30, 2021 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 6 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Bob Gene Gower Aug. 18, 2026 6.10% Amendment M&A / sale SEC
Bob G. Gower ×2 filings July 18, 2023 Initial filing SEC
MLCP GLL Funding LLC, Matthews Lane Capital Partners LLC, Daniel B. Silvers ×3 filings July 7, 2022 Initial filing SEC
Richard Wright July 12, 2021 Initial filing SEC
William Chang July 12, 2021 Initial filing SEC
Lynn Kirkpatrick July 12, 2021 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 1 ETF

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
VXF · VANGUARD INDEX FUNDS 0.00% 12,854 SH Aug. 8, 2026 Daily