ENSC Ensysce Biosciences, Inc. - Common Stock

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$0.29
Price · May 20, 2026
Fundamentals as of May 15, 2026

ENSC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$0.29
Market Cap
$4M
P/E (TTM)
-0.2
EPS (TTM)
$-3.98
Revenue (TTM)
$5M
Div Yield
ROE
-294.0%
Debt/Equity
0.1
52W Range
$0 – $3

ENSC Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $5M
6-point trend, +28.9%
2020-12-31 2025-12-31
EPS $-3.98
6-point trend, -3.98
2020-12-31 2025-12-31
Free Cash Flow $-8M
2025-12-31 2025-12-31
Margins -200.9%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
ENSC
Peer Median
P/E (TTM)
5-point trend, +100.0%
-0.2
P/S (TTM)
5-point trend, -100.0%
0.8
1.8
P/B
5-point trend, +100.0%
1.3
2.2
EV / EBITDA
5-point trend, +100.0%
-0.0
Price / FCF
-0.5

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
ENSC
Peer Median
Operating Margin
5-point trend, +64.1%
-202.1%
Net Profit Margin
5-point trend, +75.7%
-200.9%
-656.1%
ROA
5-point trend, +55.1%
-156.0%
-55.7%
ROE
5-point trend, -172.2%
-294.0%
-146.7%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
ENSC
Peer Median
Debt / Equity
5-point trend, +105.9%
0.1
94.6
Current Ratio
5-point trend, +66.9%
1.6
1.6
Quick Ratio
5-point trend, +26.8%
0.9

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
ENSC
Peer Median
Revenue YoY
5-point trend, +43.5%
-2.8%
Revenue CAGR 3Y
5-point trend, +43.5%
26.2%
Revenue CAGR 5Y
5-point trend, +43.5%
5.2%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
ENSC
Peer Median
EPS (Diluted)
5-point trend, -168.9%
$-3.98

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
ENSC
Peer Median

ENSC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 7 analysts
  • Strong Buy 2 28.6%
  • Buy 4 57.1%
  • Hold 1 14.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

1 analysts · 2026-05-19
Median target $16.45 +5625.7%
Mean target $16.45 +5625.7%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.39%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.52 $-0.74 0.22%
Dec. 31, 2025 $-0.75 $-1.29 0.54%
Sept. 30, 2025 $-1.29 $-0.88 -0.41%
June 30, 2025 $-0.79 $-1.20 0.41%
March 31, 2025 $-1.39 $-3.08 1.7%
Dec. 31, 2024 $-2.90 $-2.79 -0.11%

Peer Comparison Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ENSC $4M -0.2 -2.8% -200.9% -294.0%
DRMA
MBIO -2.5 -30.9%
AKTX $26.17B -64.1%
BRTX $10M -0.7 -10.3% -3959.4% -547.6% 93.4%
CDIO
REVB
GRI $122.9K -0.0 -256.3%
ALZN $5M -0.5 -121.7%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 15
Annual Income Statement data for ENSC
Metric Trend 202520242023202220212020
Revenue 6-point trend, +28.9% $5M $5M $2M $3M $4M $4M
R&D Expense 6-point trend, +136.4% $10M $7M $8M $20M $5M $4M
SG&A Expense 6-point trend, +326.9% $5M $5M $5M $7M $19M $1M
Operating Expenses 6-point trend, +176.1% $15M $12M $13M $27M $23M $6M
Operating Income 6-point trend, -534.8% $-10M $-7M $-11M $-24M $-20M $-2M
Interest Expense 4-point trend, -64.4% · · $353.9K $109.5K $1M $995.5K
Interest Income · · · · · $719.6K
Other Non-op 5-point trend, +126.0% $73.4K $17.3K $15.4K $86.2K $-282.3K ·
Pretax Income · · · · · $5M
Net Income 6-point trend, -6225.5% $-10M $-8M $-11M $-24M $-29M $-160.9K
EPS (Basic) 6-point trend, -3.98 $-3.98 $-11.45 $-70.40 $-139.42 $-29.64 $0.00
EPS (Diluted) 6-point trend, -3.98 $-3.98 $-11.45 $-70.40 $-139.42 $-1.48 $0.00
Shares (Basic) 6-point trend, -83.8% 2,557,377 697,686 150,937 179,925 1,008,227 15,768,725
Shares (Diluted) 6-point trend, -84.5% 2,557,377 697,686 150,937 179,925 20,164,503 16,507,387
EBITDA 6-point trend, -648.1% $-10M $-7M $-11M $-24M $-20M $-1M
Balance Sheet 19
Annual Balance Sheet data for ENSC
Metric Trend 202520242023202220212020
Cash & Equivalents 6-point trend, +2119.4% $4M $4M $1M $3M $12M $194.2K
Prepaid Expense 6-point trend, +1496.6% $3M $2M $1M $2M $3M $157.5K
Other Current Assets 3-point trend, +14.2% $20.6K $18.0K $18.0K · · ·
Current Assets 6-point trend, +1982.6% $7M $5M $2M $5M $16M $347.9K
PP&E (Net) 2-point trend, +82104.6% $124.1K · · · · $151
Other Non-current Assets 6-point trend, +2104.6% $83.3K $252.6K $419.2K $585.9K $754.8K $3.8K
Total Assets 6-point trend, +2018.3% $7M $6M $3M $6M $16M $351.8K
Accounts Payable 6-point trend, +89.5% $3M $1M $2M $3M $301.1K $2M
Short-term Debt 6-point trend, -92.8% $306.7K $301.7K $854.7K $4M $13M $4M
Current Liabilities 6-point trend, -34.8% $5M $2M $3M $9M $16M $7M
Other Non-current Liabilities 4-point trend, -99.7% · $10.1K $26.4K $310.3K $4M ·
Total Liabilities 6-point trend, -34.8% $5M $2M $3M $10M $25M $7M
Total Debt 5-point trend, -97.6% $306.7K $301.7K $854.7K $4M $13M ·
Common Stock 6-point trend, -70.9% $459 $136 $21 $53 $124 $1.6K
Paid-in Capital 6-point trend, +188.7% $143M $133M $121M $107M $78M $50M
Retained Earnings 6-point trend, -149.7% $-140M $-130M $-122M $-111M $-86M $-56M
Stockholders' Equity 6-point trend, +149.9% $3M $4M $-322.9K $-4M $-8M $-6M
Liabilities + Equity 6-point trend, +2018.3% $7M $6M $3M $6M $16M $351.8K
Shares Outstanding 6-point trend, -71.0% 4,574,977 1,355,773 209,739 534,490 1,232,160 15,768,725
Cash Flow 11
Annual Cash Flow data for ENSC
Metric Trend 202520242023202220212020
Stock-based Comp 6-point trend, -0.9% $177.1K $110.7K $879.2K $1M $121.8K $178.7K
Operating Cash Flow 6-point trend, -525.8% $-8M $-8M $-11M $-18M $-8M $-1M
CapEx $123.6K · · · · ·
Investing Cash Flow 3-point trend, -100.1% $-123.6K · · $4.5K · $183M
Stock Issued · · · · $7M ·
Stock Repurchased · · · · · $185M
Net Stock Activity 2-point trend, +103.6% · · · · $7M $-185M
Financing Cash Flow 6-point trend, +694.4% $9M $10M $9M $9M $20M $1M
Net Change in Cash 6-point trend, +648.6% $808.3K $2M $-2M $-9M $12M $-147.3K
Taxes Paid 6-point trend, +56.2% $2.5K $3.2K $3.2K $1.6K $1.6K $1.6K
Free Cash Flow $-8M · · · · ·
Profitability 5
Annual Profitability data for ENSC
Metric Trend 202520242023202220212020
Operating Margin 5-point trend, +64.1% -202.1% -129.2% -480.5% -959.9% -562.7% ·
Net Margin 5-point trend, +75.7% -200.9% -153.3% -476.4% -959.3% -825.4% ·
EBITDA Margin 5-point trend, +64.1% -202.1% -129.2% -480.5% -959.9% -562.7% ·
ROA 5-point trend, +55.1% -156.0% -192.3% -247.3% -217.1% -347.6% ·
ROE 5-point trend, -172.2% -294.0% -471.8% 526.4% 417.6% 407.1% ·
Liquidity & Solvency 4
Annual Liquidity & Solvency data for ENSC
Metric Trend 202520242023202220212020
Current Ratio 5-point trend, +66.9% 1.6 2.4 0.7 0.6 1.0 ·
Quick Ratio 5-point trend, +26.8% 0.9 1.6 0.3 0.3 0.7 ·
Debt / Equity 5-point trend, +105.9% 0.1 0.1 -2.6 -1.1 -1.6 ·
Interest Coverage 3-point trend, -97.4% · · -30.3 -221.2 -15.3 ·
Efficiency 1
Annual Efficiency data for ENSC
Metric Trend 202520242023202220212020
Asset Turnover 5-point trend, +84.4% 0.8 1.3 0.5 0.2 0.4 ·
Per Share 5
Annual Per Share data for ENSC
Metric Trend 202520242023202220212020
Book Value / Share 5-point trend, +319.7% $0.70 $2.74 $-0.10 $-0.58 $-0.32 ·
Revenue / Share 4-point trend, +1031.5% $1.98 $7.47 $0.99 · $0.18 ·
Cash Flow / Share 4-point trend, -646.9% $-3.05 $-10.75 $-4.76 · $-0.41 ·
Cash / Share 5-point trend, +89.3% $0.94 $2.58 $0.36 $0.49 $0.50 ·
EPS (TTM) 6-point trend, -3.98 $-3.98 $-11.45 $-70.40 $-139.42 $-1.48 $0.00
Growth Rates 3
Annual Growth Rates data for ENSC
Metric Trend 202520242023202220212020
Revenue YoY 5-point trend, +73.0% -2.8% 133.6% -11.6% -28.5% -10.2% ·
Revenue CAGR 3Y 3-point trend, +252.0% 26.2% 13.8% -17.2% · · ·
Revenue CAGR 5Y 5.2% · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for ENSC
Metric Trend 202520242023202220212020
Revenue TTM 6-point trend, +28.9% $5M $5M $2M $3M $4M $4M
Net Income TTM 6-point trend, -6225.5% $-10M $-8M $-11M $-24M $-29M $-160.9K
Market Cap 5-point trend, -100.0% $4M $11M $50M $866M $416.96B ·
Enterprise Value 5-point trend, -100.0% $205.3K $8M $50M $867M $416.96B ·
P/E 5-point trend, +100.0% -0.2 -0.7 -0.2 -1.0 -11432.4 ·
P/S 5-point trend, -100.0% 0.8 2.1 22.4 343.2 118079.5 ·
P/B 5-point trend, +100.0% 1.3 3.0 -154.9 -233.1 -52925.8 ·
P / Tangible Book 2-point trend, -56.0% 1.3 3.0 · · · ·
P / Cash Flow 5-point trend, +100.0% -0.5 -1.5 -4.6 -48.4 -50588.8 ·
P / FCF -0.5 · · · · ·
EV / EBITDA 5-point trend, +100.0% -0.0 -1.2 -4.6 -35.8 -20984.1 ·
EV / FCF -0.0 · · · · ·
EV / Revenue 5-point trend, -100.0% 0.0 1.5 22.3 343.6 118079.6 ·
Earnings Yield 6-point trend, -4.33 -432.6% -140.7% -442.8% -103.3% -0.01% 0.00%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $5M$5M$2M$3M$4M
Operating Margin % -202.1%-129.2%-480.5%-959.9%-562.7%
Net Income $-10M$-8M$-11M$-24M$-29M
Diluted EPS $-3.98$-11.45$-70.40$-139.42$-1.48
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.10.1-2.6-1.1-1.6
Current Ratio 1.62.40.70.61.0
Quick Ratio 0.91.60.30.30.7
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-8M

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