KALA KALA BIO, Inc. - Common Stock
NASDAQ · Biotechnology · View on SEC EDGAR ↗ close Oct 2, 2026 10-K/10-Q Aug 19, 2026
$0.39
· of 52w range
· above low
· to high
$0.1052w low
$5.8852w high
Market Cap (MRQ)
$7M
P/E
-0.0
EPS
$-3.31
Revenue
$0
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52W Range
$0–$6
Analyst Rating
HOLD
Price Target
·
P/E
-0.0
ROE
-1423.8%
Net Profit Margin
·
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KALA Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$0.39
Market Cap (MRQ)
$7M
P/E
-0.0
EPS
$-3.31
Revenue
$0
ROE
-1423.8%
52W Range
$0–$6
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Stock splits
| Ex-date | Split | Type |
|---|---|---|
| May 11, 2026 | 1-for-50 | Reverse |
| Oct. 21, 2022 | 1-for-50 | Reverse |
About KALA BIO, Inc. - Common Stock Company overview from Wikipedia
sectorHealthcare
industryBiotechnology
employees6
countryUS
10-Year Performance Revenue, net income, margins and EPS trends
Revenue$02016-12-31 → 2025-12-31
EPS$-3.312020-12-31 → 2025-12-31
Free Cash Flow·2017-12-31 → 2019-12-31
Net margin·2019-12-31 → 2022-12-31
Valuation & Ratios
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
| Metric | 5Y trend | KALA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| P/E | -0.05Y avg ≈-0.6 | ≈-0.6 | · | · | |
| P/B (MRQ) | 0.85Y avg ≈49.5 | ≈49.5 | · | · | |
| Price / Cash Flow | -0.05Y avg ≈-8.0 | ≈-8.0 | · | · | |
| Price / Tangible Book | 0.05Y avg ≈49.5 | ≈49.5 | · | · |
Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.
Profitability Gross, operating and net margins; ROE, ROA, ROIC
| Metric | 5Y trend | KALA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| ROA | -83.0%5Y avg ≈-66.0% | ≈-66.0% | -134.9% | Top tier | |
| ROE | -1423.8%5Y avg ≈-627.6% | ≈-627.6% | -412.8% | Weak |
Financial Health Debt, liquidity, solvency — balance sheet strength
| Metric | 5Y trend | KALA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Current Ratio (MRQ) | 6.95Y avg ≈4.0 | ≈4.0 | 2.6 | Strong liquidity | |
| Quick Ratio | 3.05Y avg ≈3.6 | ≈3.6 | 2.0 | Strong liquidity |
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
No data for this ratio group yet
Not enough fundamentals data to compute this ratio group yet.
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
| Metric | 5Y trend | KALA | 5Y avg | Peer Median | Verdict |
|---|---|---|---|---|---|
| Asset Turnover | 0.05Y avg ≈0.0 | ≈0.0 | · | · | |
| Revenue / Employee | ≈$0.00 | · | · | · |
value · ≈ 5Y avg · industry median · verdict relative to median
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
30.9%
| Period | Report | EPS Actual | EPS Est | Surprise |
|---|---|---|---|---|
| Dec. 31, 2025 | $-33.50 | $-73.44 | 54.4% | |
| Sept. 30, 2025 | $-43.00 | $-73.72 | 41.7% | |
| June 30, 2025 | $-85.50 | $-86.87 | 1.6% | |
| March 31, 2025 | $-70.50 | $-103.53 | 31.9% | |
| Dec. 31, 2024 | $-1.74 | $-2.33 | 25.2% |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $4M | $11M | $6M | $6M | · | $0 | $0 | |
| R&D Expense | · | · | · | · | · | $18M | $27M | $29M | $29M | $25M | |
| SG&A Expense | $24M | $18M | $21M | $65M | $105M | $81M | $65M | $35M | $11M | $8M | |
| Operating Expenses | $39M | $41M | $40M | $86M | $141M | $103M | $94M | $65M | $40M | $33M | |
| Operating Income | $-39M | $-41M | $-40M | $-82M | $-130M | $-96M | $-88M | $-65M | $-40M | $-33M | |
| Interest Expense | · | · | $6M | $7M | $8M | $9M | $8M | $3M | $1M | $767.0K | |
| Interest Income | $1M | $2M | $3M | $664.0K | $104.0K | $493.0K | $2M | $2M | $527.0K | $147.0K | |
| Other Non-op | $5M | · | $-4M | $-926.0K | · | · | · | · | · | · | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | |
| Net Income | $-27M | $-39M | $-42M | $-45M | $-143M | $-104M | $-94M | $-67M | $-42M | $-33M | |
| EPS (Basic) | $-3.31 | $-10.15 | $-17.35 | $-29.48 | $-108.32 | $-1.99 | · | · | · | · | |
| EPS (Diluted) | $-3.31 | $-10.15 | $-17.35 | $-29.48 | $-108.32 | $-1.99 | · | · | · | · | |
| Shares (Basic) | 8,148,275 | 3,796,047 | 2,432,008 | 1,520,611 | 1,316,495 | 52,377,526 | · | · | · | · | |
| Shares (Diluted) | 8,148,275 | 3,796,047 | 2,432,008 | 1,520,611 | 1,316,495 | 52,377,526 | · | · | · | · | |
| EBITDA | $-39M | $-41M | $-39M | $-81M | $-129M | $-95M | $-88M | $-65M | $-40M | · |
Balance Sheet
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $8M | $51M | $51M | $70M | $92M | $77M | $85M | $171M | $115M | $45M | |
| Short-term Investments | · | · | · | · | · | $76M | · | · | · | · | |
| Receivables | · | · | · | $195.0K | $15M | $10M | $12M | · | · | · | |
| Inventory | · | · | · | · | $9M | $5M | $5M | $4M | · | · | |
| Prepaid Expense | $2M | $2M | $2M | $8M | $6M | $3M | $4M | $2M | $648.0K | $154.0K | |
| Other Current Assets | · | · | · | · | · | · | · | $477.0K | $196.0K | $41.0K | |
| Current Assets | $9M | $53M | $53M | $86M | $124M | $171M | $105M | $177M | $115M | $46M | |
| PP&E (Net) | · | $749.0K | $753.0K | $400.0K | $3M | $3M | $3M | $2M | $786.0K | $594.0K | |
| PP&E (Gross) | $869.0K | $2M | $2M | $2M | $6M | $7M | $5M | $4M | $2M | $2M | |
| Accum. Depreciation | $869.0K | $1M | $1M | $1M | $3M | $3M | $3M | $2M | $2M | $1M | |
| Total Assets | $9M | $55M | $56M | $87M | $139M | $222M | $154M | $221M | $117M | $46M | |
| Accounts Payable | $986.0K | $628.0K | $919.0K | $3M | $5M | $2M | $3M | $5M | $1M | $997.0K | |
| Accrued Liabilities | · | · | $6M | $9M | $21M | $19M | $21M | $11M | $7M | $4M | |
| Current Liabilities | $2M | $17M | $8M | $26M | $37M | $22M | $25M | $17M | $15M | $6M | |
| Capital Leases | · | $1M | $2M | · | $548.0K | · | · | $29M | · | · | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | $8.0K | $17.0K | |
| Total Liabilities | $2M | $43M | $48M | $68M | $123M | $122M | $125M | $116M | $27M | $16M | |
| Long-term Debt | · | $29M | $34M | $43M | $80M | $75M | $75M | $75M | $19M | $10M | |
| Total Debt | · | $30M | $34M | $43M | $79M | $72M | $71M | $70M | $19M | · | |
| Common Stock | $1.0K | $6.0K | $3.0K | $2.0K | $1.0K | $59.0K | $36.0K | $34.0K | $25.0K | $1.0K | |
| Paid-in Capital | $702M | $680M | $637M | $606M | $559M | $500M | $325M | $306M | $224M | $4M | |
| Retained Earnings | $-695M | $-668M | $-629M | $-587M | $-542M | $-400M | $-295M | $-201M | $-134M | $-92M | |
| AOCI | · | · | · | · | · | $4.0K | · | · | · | · | |
| Stockholders' Equity | $7M | $12M | $8M | $19M | $17M | $100M | $30M | $105M | $90M | $-88M | |
| Liabilities + Equity | $9M | $55M | $56M | $87M | $139M | $222M | $154M | $221M | $117M | $46M | |
| Shares Outstanding | 556,995 | 6,091,182 | 2,759,372 | 1,706,971 | 1,322,464 | 58,915,375 | 36,086,254 | 33,863,077 | 24,538,309 | 1,181,429 |
Cash Flow
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $317.0K | $259.0K | $303.0K | $537.0K | $975.0K | $912.0K | $843.0K | · | · | · | |
| Stock-based Comp | $7M | $8M | $7M | $7M | $16M | $13M | $10M | $9M | $4M | $2M | |
| Other Non-cash | $-12M | $481.0K | $7M | $-42M | $17M | $-591.0K | · | · | · | · | |
| Operating Cash Flow | $-32M | $-29M | $-28M | $-79M | $-108M | $-91M | $-93M | $-54M | $-34M | $-27M | |
| CapEx | · | · | · | · | · | · | $1M | $2M | $480.0K | $153.0K | |
| Investing Cash Flow | $-15.0K | $-208.0K | $-429.0K | $63M | $71M | $-78M | $-1M | $-2M | $-480.0K | $-153.0K | |
| Debt Issued | · | · | · | · | $78M | · | · | $72M | $10M | $1M | |
| Net Debt Issued | · | · | · | · | $78M | · | · | $72M | $10M | · | |
| Stock Issued | $9M | $3M | $19M | $1M | $41M | $159M | $8M | $30M | $30M | · | |
| Net Stock Activity | $9M | $3M | $19M | $1M | $41M | $159M | · | $30M | $30M | · | |
| Financing Cash Flow | $-12M | $30M | $9M | $-8M | $43M | $161M | $9M | $124M | $104M | $67M | |
| Net Change in Cash | $-44M | $286.0K | $-20M | $-24M | $5M | $-8M | $-85M | $68M | $69M | $40M | |
| Free Cash Flow | · | · | · | · | · | · | $-94M | $-56M | $-35M | · |
Profitability
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | -2099.3% | -1158.8% | -1512.6% | -1452.5% | · | · | · | |
| Net Margin | · | · | · | -1151.6% | -1268.7% | -1639.8% | -1553.3% | · | · | · | |
| EBITDA Margin | · | · | · | -2085.5% | -1150.1% | -1498.3% | -1452.5% | · | · | · | |
| ROA | -83.0% | -69.1% | -59.1% | -39.6% | -79.0% | -55.5% | -50.3% | -39.6% | -52.0% | · | |
| ROE | -1423.8% | -401.3% | -450.7% | -497.9% | -364.4% | -101.3% | -207.9% | -83.5% | -4403.9% | · |
Liquidity & Solvency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.8 | 3.1 | 6.3 | 3.3 | 3.3 | 7.7 | 4.3 | 10.4 | 8.0 | · | |
| Quick Ratio | 3.0 | 3.0 | 6.1 | 2.8 | 2.9 | 7.3 | 3.9 | 10.0 | 7.9 | · | |
| Debt / Equity | · | 2.5 | 4.6 | 2.3 | 4.7 | 0.7 | 2.4 | 0.7 | 0.2 | · | |
| LT Debt / Equity | · | 1.6 | 4.6 | 2.0 | 4.7 | 0.7 | 2.4 | 0.7 | 0.1 | · | |
| Interest Coverage | · | · | -6.8 | -11.2 | -15.5 | -11.2 | -10.4 | -19.5 | -39.1 | · |
Efficiency
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | 0.0 | · | 0.0 | · | |
| Receivables Turnover | · | · | · | 0.5 | 0.9 | 0.6 | 1.1 | · | · | · |
Per Share
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $0.25 | $2.02 | $2.72 | $11.12 | $0.26 | $1.70 | $0.82 | $3.10 | $3.65 | · | |
| Revenue / Share | $0.00 | $0.00 | $0.00 | $2.56 | $0.17 | · | · | · | · | · | |
| Cash Flow / Share | $-3.93 | $-7.74 | $-11.48 | $-51.89 | $-1.66 | · | · | · | · | · | |
| Cash / Share | $0.27 | $8.40 | $18.44 | $41.30 | $1.41 | $1.31 | $2.37 | $5.05 | $4.67 | · | |
| EPS (TTM) | $-3.31 | $-10.15 | $-17.35 | $-29.48 | $-108.32 | $-1.99 | · | · | · | · |
Growth Rates
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | · | · | · | -65.4% | 76.7% | · | · | · | · | · |
Valuation (TTM)
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $0 | $0 | $4M | $11M | $6M | $6M | · | $0 | · | |
| Net Income TTM | $-27M | $-39M | $-42M | $-45M | $-143M | $-104M | $-94M | $-67M | $-42M | · | |
| Market Cap | $15M | $42M | $19M | $65M | $3.96B | $19.97B | $6.66B | $8.28B | $22.69B | · | |
| Enterprise Value | · | $22M | $3M | $38M | $3.95B | $19.89B | $6.64B | $8.18B | $22.59B | · | |
| P/E | -0.2 | -0.7 | -0.4 | -1.3 | -0.6 | -170.4 | · | · | · | · | |
| P/S | · | · | · | 16.7 | 352.6 | 3139.3 | 1096.1 | · | · | · | |
| P/B | 2.2 | 3.4 | 2.6 | 3.4 | 235.8 | 199.7 | 224.2 | 78.9 | 253.0 | · | |
| P / Tangible Book | 2.2 | 3.4 | 2.6 | 3.4 | 235.8 | 199.7 | · | · | · | · | |
| P / Cash Flow | -0.5 | -1.4 | -0.7 | -0.8 | -36.6 | -220.2 | -71.8 | -153.0 | -665.3 | · | |
| P / FCF | · | · | · | · | · | · | -70.8 | -148.6 | -656.1 | · | |
| EV / EBITDA | · | -0.5 | -0.1 | -0.5 | -30.6 | -208.7 | -75.3 | -126.4 | -566.5 | · | |
| EV / FCF | · | · | · | · | · | · | -70.6 | -146.8 | -653.3 | · | |
| EV / Revenue | · | · | · | 9.7 | 351.4 | 3126.5 | 1093.8 | · | · | · | |
| Earnings Yield | -595.3% | -146.2% | -247.9% | -77.3% | -179.0% | -0.59% | · | · | · | · |
Income Statement
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | $420.0K | |
| R&D Expense | $59.0K | $61.0K | · | $6M | $6M | $6M | · | $5M | $5M | $6M | · | $6M | $4M | $4M | · | $5M | |
| SG&A Expense | $2M | $2M | $10M | $5M | $5M | $5M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | $6M | $6M | $10M | |
| Operating Expenses | $2M | $2M | $10M | $7M | $11M | $11M | $9M | $10M | $10M | $12M | $10M | $9M | $10M | $12M | $10M | $15M | |
| Operating Income | $-2M | $-2M | $-10M | $-7M | $-11M | $-11M | $-9M | $-10M | $-10M | $-12M | $-10M | $-9M | $-10M | $-12M | $-10M | $-15M | |
| Interest Expense | · | · | · | · | · | · | · | · | · | $1M | · | $1M | $1M | $1M | $2M | $1M | |
| Interest Income | $140.0K | $74.0K | $0 | $270.0K | $407.0K | $463.0K | $478.0K | $570.0K | $504.0K | $504.0K | $610.0K | $708.0K | $718.0K | $675.0K | $354.0K | $234.0K | |
| Other Non-op | $0 | $107.0K | $4M | $-112.0K | $-127.0K | $2M | · | · | $26.0K | $124.0K | $-5.0K | $-2M | $-119.0K | $-2M | $-1M | $443.0K | |
| Net Income | $-2M | $-2M | $686.0K | $-8M | $-11M | $-9M | $-8M | $-9M | $-10M | $-12M | $-9M | $-9M | $-10M | $-14M | $-13M | $29M | |
| EPS (Basic) | $-21.32 | $-0.14 | $0.88 | $-1.07 | $-85.64 | $-70.49 | $-0.86 | $-1.93 | $-3.16 | $-4.20 | $-2.59 | $-3.41 | $-4.36 | $-6.99 | $-7.77 | $19.39 | |
| EPS (Diluted) | $-21.32 | $-0.14 | $0.88 | $-1.07 | $-85.64 | $-70.49 | $-0.86 | $-1.93 | $-3.16 | $-4.20 | $-2.59 | $-3.41 | $-4.36 | $-6.99 | $-7.63 | $19.25 | |
| Shares (Basic) | 74,159 | 11,873,568 | · | 7,042,457 | 130,262 | 126,917 | · | 4,627,578 | 3,030,213 | 2,813,210 | · | 2,550,210 | 2,387,793 | 2,069,186 | · | 1,499,001 | |
| Shares (Diluted) | 74,159 | 11,873,568 | · | 7,042,457 | 130,262 | 126,917 | · | 4,627,578 | 3,030,213 | 2,813,210 | · | 2,550,210 | 2,387,793 | 2,069,186 | · | 1,510,421 | |
| EBITDA | $-2M | $-2M | · | $-7M | $-11M | $-11M | · | $-10M | $-10M | $-12M | · | $-9M | $-10M | $-12M | · | $-15M |
Balance Sheet
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $229.0K | $2M | $8M | $21M | $32M | $42M | $51M | $49M | $54M | $48M | $51M | $56M | $49M | $64M | $70M | $52M | |
| Short-term Investments | $7M | $7M | · | · | · | · | · | · | · | · | · | · | $10M | · | · | · | |
| Receivables | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $190.0K | |
| Inventory | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0 | |
| Prepaid Expense | $3M | $4M | $2M | $3M | $2M | $3M | $2M | $2M | $5M | $2M | $2M | $2M | $1M | $2M | $8M | $23M | |
| Current Assets | $11M | $12M | $9M | $24M | $34M | $46M | $53M | $51M | $59M | $50M | $53M | $58M | $66M | $71M | $86M | $85M | |
| PP&E (Net) | · | · | · | $603.0K | $657.0K | $695.0K | $749.0K | $762.0K | $617.0K | $714.0K | $753.0K | $802.0K | $637.0K | $504.0K | $400.0K | $517.0K | |
| PP&E (Gross) | · | · | $869.0K | · | · | · | $2M | · | · | · | $2M | · | · | · | $2M | · | |
| Accum. Depreciation | · | · | $869.0K | · | · | · | $1M | · | · | · | $1M | · | · | · | $1M | · | |
| Total Assets | $11M | $12M | $9M | $25M | $36M | $48M | $55M | $54M | $62M | $53M | $56M | $61M | $66M | $72M | $87M | $86M | |
| Accounts Payable | $1M | $1M | $986.0K | $917.0K | $658.0K | $931.0K | $628.0K | $711.0K | $665.0K | $732.0K | $919.0K | $787.0K | $760.0K | $997.0K | $3M | $7M | |
| Accrued Liabilities | · | · | · | · | · | · | · | $4M | $4M | $5M | · | $6M | $5M | $5M | $9M | $25M | |
| Current Liabilities | $2M | $2M | $2M | $33M | $16M | $23M | $17M | $24M | $19M | $12M | $8M | $10M | $10M | $10M | $26M | $40M | |
| Capital Leases | · | · | · | $1M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | · | · | · | · | |
| Total Liabilities | $2M | $2M | $2M | $34M | $39M | $43M | $43M | $47M | $48M | $46M | $48M | $50M | $49M | $49M | $68M | $87M | |
| Long-term Debt | · | · | · | $27M | $27M | $29M | $29M | $34M | $34M | $34M | · | $34M | $34M | $34M | $43M | · | |
| Total Debt | · | · | · | $28M | $28M | $31M | · | $35M | $35M | $35M | · | $34M | $34M | $33M | · | $43M | |
| Common Stock | $20.0K | $19.0K | $28.0K | $7.0K | $7.0K | $6.0K | $6.0K | $5.0K | $5.0K | $3.0K | $3.0K | $3.0K | $3.0K | $2.0K | $2.0K | $1.0K | |
| Paid-in Capital | $707M | $707M | $702M | $687M | $685M | $683M | $680M | $667M | $665M | $648M | $637M | $632M | $630M | $625M | $606M | $573M | |
| Retained Earnings | $-698M | $-697M | $-695M | $-696M | $-688M | $-677M | $-668M | $-660M | $-651M | $-641M | $-629M | $-621M | $-612M | $-602M | $-587M | $-574M | |
| AOCI | · | · | · | · | · | · | · | · | · | · | · | $1.0K | $9.0K | · | · | · | |
| Stockholders' Equity | $9M | $11M | $7M | $-9M | $-3M | $6M | $12M | $7M | $14M | $7M | $8M | $11M | $17M | $23M | $19M | $-968.0K | |
| Liabilities + Equity | $11M | $12M | $9M | $25M | $36M | $48M | $55M | $54M | $62M | $53M | $56M | $61M | $66M | $72M | $87M | $86M | |
| Shares Outstanding | 19,339,786 | 18,589,832 | 27,849,725 | 7,432,925 | 6,679,115 | 6,452,398 | 6,091,182 | 4,610,139 | 4,598,419 | 2,816,454 | 2,759,372 | 2,693,116 | 2,538,687 | 2,309,287 | 1,706,971 | 1,476,637 |
Cash Flow
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | $54.0K | $128.0K | $67.0K | $68.0K | $69.0K | $63.0K | $61.0K | $66.0K | $70.0K | $79.0K | $77.0K | $77.0K | $80.0K | $151.0K | |
| Stock-based Comp | $-136.0K | $-471.0K | $401.0K | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $960.0K | $1M | |
| Other Non-cash | · | · | · | · | · | $-2M | · | · | · | $-1M | · | · | · | $3M | · | · | |
| Operating Cash Flow | $-2M | $-3M | $-5M | $-11M | $-17M | $-9M | $-5M | $-5M | $-9M | $-11M | $-8M | $-3M | $-8M | $-10M | $-14M | $-16M | |
| Investing Cash Flow | $0 | $-7M | $0 | $1.0K | · | · | $-69.0K | $-90.0K | $-36.0K | $-13.0K | $-7.0K | $10M | $-10M | $-108.0K | $51.0K | $65M | |
| Stock Issued | · | · | · | · | · | · | $923.0K | $0 | · | · | $570.0K | $0 | $3M | $15M | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | · | · | · | · | $15M | · | · | |
| Financing Cash Flow | $0 | $4M | $-9M | $30.0K | $-3M | $-135.0K | $7M | $-180.0K | $15M | $8M | $3M | $40.0K | $3M | $3M | $32M | $-40M | |
| Net Change in Cash | $-2M | $-6M | $-14M | $-11M | $-10M | $-9M | $2M | $-5M | $6M | $-2M | $-5M | $7M | $-15M | $-7M | $18M | $9M |
Profitability
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -3468.8% | |
| Net Margin | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 6922.1% | |
| EBITDA Margin | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -3468.8% | |
| ROA | -6.8% | -5.3% | · | -19.1% | -22.8% | -17.7% | · | -15.5% | -14.9% | -18.9% | · | -11.9% | -13.8% | -15.7% | · | 20.8% | |
| ROE | -54.2% | -19.7% | · | 837.6% | -212.2% | -144.7% | · | -99.0% | -61.4% | -78.4% | · | -169.8% | 148.1% | -159.1% | · | 96.1% |
Liquidity & Solvency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 6.9 | 7.9 | · | 0.7 | 2.1 | 2.0 | · | 2.1 | 3.1 | 4.2 | · | 5.6 | 6.7 | 7.0 | · | 2.1 | |
| Quick Ratio | 4.7 | 5.6 | · | 0.6 | 2.0 | 1.8 | · | 2.1 | 2.8 | 4.1 | · | 5.4 | 6.0 | 6.2 | · | 1.3 | |
| Debt / Equity | · | · | · | -3.3 | -8.8 | 5.4 | · | 5.1 | 2.5 | 5.2 | · | 3.0 | 1.9 | 1.4 | · | -44.1 | |
| LT Debt / Equity | · | · | · | · | -5.9 | 2.6 | · | 2.5 | 1.7 | 4.3 | · | 3.0 | 1.9 | 1.4 | · | -44.1 | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -8.2 | · | -6.0 | -6.8 | -7.9 | · | -10.1 |
Efficiency
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.1 |
Per Share
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Book Value / Share | $0.47 | $0.58 | · | $-1.17 | $-0.48 | $0.88 | · | $1.49 | $2.98 | $2.37 | · | $4.17 | $6.89 | $10.16 | · | $-0.66 | |
| Revenue / Share | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $0.28 | |
| Cash Flow / Share | · | $-0.24 | · | · | $-2.54 | $-1.39 | · | · | · | $-3.85 | · | · | · | $-4.68 | · | · | |
| Cash / Share | $0.01 | $0.09 | · | $2.84 | $4.78 | $6.54 | · | $10.67 | $11.79 | $17.21 | · | $20.82 | $19.40 | $27.56 | · | $35.48 | |
| EPS (TTM) | $-21.65 | $-85.97 | · | $-158.06 | $-158.92 | $-76.44 | · | $-11.88 | $-13.36 | $-14.56 | · | $-22.39 | $0.27 | $-14.29 | · | $-107.70 |
Valuation (TTM)
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $4M | $4M | · | $4M | $4M | $4M | · | $4M | $4M | $4M | · | $4M | $4M | $4M | · | $6M | |
| Net Income TTM | $-10M | $-20M | · | $-36M | $-37M | $-36M | · | $-39M | $-39M | $-40M | · | $-46M | $-9M | $-26M | · | $-80M | |
| Market Cap | $33M | $3M | · | $11M | $32M | $37M | · | $26M | $33M | $22M | · | $24M | $37M | $35M | · | $16M | |
| Enterprise Value | · | · | · | $19M | $28M | $25M | · | $12M | $13M | $8M | · | $2M | $11M | $4M | · | $7M | |
| P/E | -0.1 | -0.0 | · | -0.0 | -0.0 | -0.1 | · | -0.5 | -0.5 | -0.5 | · | -0.4 | 54.0 | -1.1 | · | -0.1 | |
| P/S | 8.6 | 0.8 | · | 2.9 | 8.2 | 9.5 | · | 6.8 | 8.4 | 5.8 | · | 6.2 | 9.5 | 8.9 | · | 2.8 | |
| P/B | 3.7 | 0.3 | · | -1.3 | -9.9 | 6.5 | · | 3.8 | 2.4 | 3.4 | · | 2.1 | 2.1 | 1.5 | · | -16.9 | |
| P / Tangible Book | 3.7 | 0.3 | · | · | · | 6.5 | · | 3.8 | 2.4 | 3.4 | · | 2.1 | 2.1 | 1.5 | · | · | |
| P / Cash Flow | · | -1.1 | · | · | -1.9 | -4.2 | · | · | · | -2.1 | · | · | · | -3.6 | · | · | |
| EV / Revenue | · | · | · | 4.8 | 7.2 | 6.5 | · | 3.1 | 3.4 | 2.2 | · | 0.5 | 2.9 | 1.1 | · | 1.1 | |
| Earnings Yield | -1251.5% | -49693.6% | · | -10330.7% | -3338.7% | -1334.0% | · | -208.4% | -188.4% | -182.7% | · | -251.6% | 1.8% | -95.0% | · | -974.7% |
Most recent period on the left · null values shown as ·
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Revenue | $0 | $0 | $0 | $4M | $11M |
| Operating Margin % | · | · | · | -2099.3% | -1158.8% |
| Net Income | $-27M | $-39M | $-42M | $-45M | $-143M |
| Diluted EPS | $-3.31 | $-10.15 | $-17.35 | $-29.48 | $-108.32 |
| Metric | 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 |
|---|---|---|---|---|---|
| Debt / Equity | · | 2.5 | 4.6 | 2.3 | 4.7 |
| Current Ratio | 3.8 | 3.1 | 6.3 | 3.3 | 3.3 |
| Quick Ratio | 3.0 | 3.0 | 6.1 | 2.8 | 2.9 |
No data for this statement
Not enough fundamentals data to build this statement yet.
Institutional owners (13F) 4 filers · $51K total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Holders
4
Value held
$51K
New positions
0
Exited positions
29
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 0 | 29 | 0 | 1 | · |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair. Change vs prior quarter not shown: filer coverage differs too much between these two quarters for a reliable comparison.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| VANGUARD GROUP INC | $50,601 | 91,009 | 99.76% | Shares |
| Legacy Investment Solutions, LLC | $119 | 25 | 0.23% | Shares |
| HARBOUR INVESTMENTS, INC. | $5 | 3 | 0.01% | Shares |
| Motiv8 Investments LLC | $0 | 2 | 0.00% | Shares |
Activists & 5%+ owners 7 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Lazar David E. ×2 filings | July 2, 2026 | 3.90% | Amendment | · | SEC |
| SR One Capital Fund II Aggregator, LP, SR One Capital Partners II, LP, SR One Capital Management, LLC, Simeon George ×3 filings | Oct. 15, 2025 | 4.60% | Amendment | · | SEC |
| Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker, Felix J. Baker ×3 filings | Oct. 2, 2025 | 9.99% | Amendment | Board campaign | SEC |
| Longitude Capital Partners II, LLC, Longitude Venture Partners II, L.P., Longitude Capital Partners IV, LLC, Longitude Venture Partners IV, L.P., Patrick G. Enright, Juliet Tammenoms Bakker ×4 filings | Oct. 18, 2023 | · | Initial filing | · | SEC |
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×6 filings | June 3, 2022 | · | Initial filing | · | SEC |
| Lagunita Biosciences, LLC, Lagunita, LLC, Garland Investments, L.P., Mark S. Blumenkranz ×3 filings | Nov. 26, 2021 | · | Initial filing | M&A / sale | SEC |
| RA Capital Management, LLC, Peter Kolchinsky ×2 filings | Oct. 5, 2018 | · | Initial filing | Passive investment | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Company insiders 22 insiders · 6 officers · 15 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Lazar David E. | Chief Executive Officer | Dec. 18, 2025 J | · | 0 | 0 | $0 |
| Mary Reumuth | CHIEF FINANCIAL OFFICER | Oct. 23, 2025 S | 28,906 | 0 | 2 | $-27,544 |
| Darius Kharabi | CHIEF BUSINESS OFFICER | Oct. 22, 2025 S | 41,760 | 0 | 1 | $-17,269 |
| Eric Trachtenberg | Chief Legal Officer, Chief Compliance Officer and Secretary | Jan. 4, 2024 A | 68,066 | 0 | 0 | $0 |
| Hongming Chen | CHIEF SCIENTIFIC OFFICER | Oct. 27, 2021 S | 204,515 | 0 | 0 | $0 |
| Michele Larussa | Sr. VP, Regulatory and Quality | Feb. 7, 2018 A | · | 0 | 0 | $0 |
| Mark T Iwicki | Director | Oct. 23, 2025 S | 103,540 | 0 | 1 | $-125,464 |
| Todd Bazemore | Director | Oct. 22, 2025 S | 35,932 | 0 | 1 | $-39,647 |
| Marjan Farid | Director | June 15, 2025 A | 10,242 | 0 | 0 | $0 |
| Daniel C. Myers | Director | June 15, 2025 A | 10,374 | 0 | 0 | $0 |
| Howard B Rosen | Director | June 15, 2025 A | 16,240 | 0 | 0 | $0 |
| Andrew I Koven | Director | June 15, 2025 A | 16,972 | 0 | 0 | $0 |
| Gregory D Perry | Director | June 15, 2025 A | 13,344 | 0 | 0 | $0 |
| Mark S. Blumenkranz | Director | June 11, 2024 A | 13,091 | 0 | 0 | $0 |
| Robert Bradley Paull | Director | June 16, 2022 A | 40,000 | 0 | 0 | $0 |
| Gregory Grunberg | Director | June 17, 2021 A | 40,000 | 0 | 0 | $0 |
| Rajeev Shah | Director | June 17, 2021 A | 20,000 | 0 | 0 | $0 |
| Hill Paulina | Director | June 12, 2018 A | · | 0 | 0 | $0 |
| Robert Langer | Director | June 12, 2018 A | · | 0 | 0 | $0 |
| Robert I Tepper | Director | July 25, 2017 C | 1,621,092 | 0 | 0 | $0 |
| Hadley Harbor Master Investors (Cayman) L.P. | 10% owner | July 25, 2017 C | 846,566 | 0 | 0 | $0 |
| Romulus K Brazzell | · | Oct. 22, 2025 S | 35,952 | 0 | 1 | $-38,801 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
ETF ownership Held by 1 ETF
Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.
| Fund | Weight | Units | As of | Source |
|---|---|---|---|---|
| VXF · VANGUARD INDEX FUNDS | 0.00% | 220,623 SH | Aug. 19, 2026 | Daily |
KALA Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
rating · 6 analysts
SELL
0 0.0%
Strong Buy
0 0.0%
Buy
3 50.0%
Hold
1 16.7%
Sell
2 33.3%
Strong Sell
Peer comparison (GICS sub-industry) Key metrics vs sector peers
FY basis, prices as of each company's last fiscal year-end close.
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Source: SEC 10-Q filed Aug 19, 2026