PHIO Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $0.99
Market Cap (MRQ) $11M
P/E -0.2
EPS $-9.08
ROE -57.5%
52W Range $1–$4

PHIO Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

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Stock splits 6
Ex-date Split Type
July 5, 2024 1-for-9 Reverse
Jan. 26, 2023 1-for-12 Reverse
Jan. 15, 2020 1-for-55 Reverse
Jan. 8, 2018 1-for-10 Reverse
April 18, 2016 1-for-10 Reverse
July 24, 2013 1-for-30 Reverse

10-Year Performance Revenue, net income, margins and EPS trends

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Revenue·
2016-12-31 → 2020-12-31
EPS$-9.08
2021-12-31 → 2024-12-31
Free Cash Flow$-8M
2016-12-31 → 2025-12-31
Net margin·
2016-12-31 → 2024-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend PHIO 5Y avg Peer Median Verdict
P/E -0.25Y avg ≈-2.6 ≈-2.6 · ·
P/B (MRQ) 0.95Y avg ≈2.2 ≈2.2 1.4 Undervalued
Price / FCF (TTM) -0.95Y avg ≈-2.0 ≈-2.0 · ·
Price / Cash Flow (TTM) -0.95Y avg ≈-2.0 ≈-2.0 · ·
Price / Tangible Book 0.65Y avg ≈15.1 ≈15.1 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

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Avg Surprise 0.17%
Next Report Nov 11, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 12, 2026 $-0.36 $-0.37 2.0%
March 31, 2026 May 13, 2026 $-0.34 $-0.24 -41.8%
Dec. 31, 2025 $-0.25 $-0.35 27.0%
Sept. 30, 2025 $-0.44 $-0.46 4.1%
June 30, 2025 $-0.45 $-0.37 -22.5%
Dec. 31, 2024 $-0.85 $-1.25 32.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

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Income Statement 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue ·····$0$21.0K$138.0K$15.0K$19.0K$34.0K·
R&D Expense $5M$4M$6M$7M$9M$4M$4M$4M$5M$5M$7M$6M
SG&A Expense $5M$4M$4M$4M$5M$5M$5M$3M$4M$4M$3M$3M
Operating Expenses $9M$7M$11M$11M$14M$9M$9M$8M$14M$9M$10M$9M
Operating Income $-9M$-7M$-11M$-11M$-14M$-9M$-9M$-7M$-14M$-9M$-10M$-9M
Other Non-op $2.0K$6.0K$-2.0K$-18.0K$224.0K$-1.0K$79.0K$4.0K$-11.0K$6.0K$-2.0K$9.0K
Pretax Income ···$-11M$-13M$-9M$-9M$-7M$-14M$-9M$-10M$-9M
Income Tax $0$0$0$0$0$0$0$0$-2M$0$0$0
Net Income $-9M$-7M$-11M$-11M$-13M$-9M$-9M$-7M$-12M$-9M$-10M$-9M
EPS (Basic) $-1.45$-9.08$-46.76$-10.10$-12.43·······
EPS (Diluted) ·$-9.08$-46.76$-10.10$-12.43·······
Shares (Basic) 5,984,017787,466231,5081,136,5661,069,234·······
Shares (Diluted) ·787,466231,5081,136,5661,069,234·······
EBITDA $-9M$-7M$-11M$-11M·$-9M$-9M$-7M$-14M$-9M$-10M$-9M
Balance Sheet 20
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents $21M$5M$8M$12M$24M$14M$7M$15M$4M$13M$5M$8M
Prepaid Expense $445.0K$354.0K$832.0K$615.0K$620.0K$870.0K$316.0K$221.0K$201.0K$150.0K$311.0K$442.0K
Current Assets $21M$6M$9M$12M$25M$15M$7M$15M$4M$13M$11M$9M
PP&E (Net) $11.0K$2.0K$6.0K$183.0K$133.0K$157.0K$210.0K$172.0K$248.0K$114.0K$163.0K$183.0K
PP&E (Gross) $239.0K$308.0K$1M$1M$1M·······
Accum. Depreciation $228.0K$306.0K$1M$1M$1M$1M$1M$981.0K$900.0K$831.0K$778.0K$702.0K
Other Non-current Assets ·$0$3.0K$24.0K$27.0K$18.0K$18.0K$0$18.0K$27.0K$18.0K$18.0K
Total Assets $21M$6M$9M$13M$25M$16M$8M$15M$4M$13M$11M$9M
Accounts Payable $435.0K$253.0K$657.0K$779.0K$283.0K$728.0K$809.0K$550.0K$511.0K$917.0K$1M$285.0K
Accrued Liabilities $905.0K$762.0K$942.0K$1M$3M$1M$964.0K$1M$2M$2M$1M$1M
Current Liabilities ·$1M$2M$2M$3M$2M$2M$2M$2M$3M$2M$1M
Capital Leases ·$0$0$35.0K$170.0K$295.0K$411.0K$0····
Total Liabilities $1M$1M$2M$2M$3M$3M$2M$2M····
Total Debt ·····$231.0K······
Common Stock $1.0K$0$0$0$0$1.0K$1.0K$0$0$0$1.0K$2.0K
Paid-in Capital $175M$151M$147M$139M$139M$117M$101M$99M$80M$73M$66M$48M
Retained Earnings $-155M$-146M$-139M$-128M$-117M$-104M$-95M$-86M$-79M$-66M$-57M$-47M
Stockholders' Equity $20M$5M$8M$11M$22M$13M$6M$14M$2M$11M$9M$3M
Liabilities + Equity $21M$6M$9M$13M$25M$16M$8M$15M$4M$13M$11M$9M
Shares Outstanding 11,617,2501,733,717416,3681,139,0241,127,9175,780,973669,433342,5782,429,9931,300,318653,48521,984,272
Cash Flow 12
Metric Trend 202520242023202220212020201920182017201620152014
D&A $3.0K$2.0K$56.0K$71.0K$75.0K$72.0K$67.0K$81.0K$70.0K$53.0K$77.0K$87.0K
Stock-based Comp $481.0K$147.0K$303.0K$414.0K$480.0K$136.0K$300.0K$282.0K$314.0K$756.0K$2M$2M
Deferred Tax ·······$0$-2M$-4M$-4M$-3M
Other Non-cash $235.0K$-111.0K$-282.0K$-1M·$-216.0K$-104.0K$-523.0K$4M$4M$5M$2M
Operating Cash Flow $-8M$-7M$-11M$-12M$-12M$-9M$-9M$-8M$-10M$-8M$-7M$-8M
CapEx $12.0K$1.0K$5.0K$121.0K$51.0K$19.0K$72.0K$5.0K$203.0K$4.0K$57.0K$95.0K
Investing Cash Flow $-12.0K$8.0K$-5.0K$-121.0K$-51.0K$-19.0K$-72.0K$-5.0K$-103.0K···
Stock Issued ·······$1M$290.0K·$9M$2M
Net Stock Activity ·······$1M··$9M$2M
Financing Cash Flow $24M$4M$7M$-26.0K$22M$16M$772.0K$19M$292.0K···
Net Change in Cash $16M$-3M·····$11M$-9M$8M$-3M$-3M
Free Cash Flow $-8M$-7M$-11M$-12M·$-9M$-9M$-8M$-10M$-8M$-7M$-8M
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin ·-3197.8%····-42795.2%-5336.2%-93746.7%-47447.4%··
Net Margin ·-3095.2%····-42419.0%-5333.3%-83013.3%-47336.8%··
Pretax Margin ······-42419.0%-5333.3%-93820.0%-47336.8%··
EBITDA Margin ·-3197.0%····-42476.2%-5277.5%-93280.0%-47168.4%··
ROA -63.9%-94.7%-97.6%-60.5%·-74.0%-76.3%-75.8%-142.3%-73.2%-100.5%-73.0%
ROE -57.5%-147.9%-144.9%-94.2%·-61.8%-133.4%-96.0%-196.3%-91.1%-175.7%-229.0%
ROIC ···-105.8%·-66.4%-156.3%-54.2%-678.8%-83.0%-115.1%-321.5%
Liquidity & Solvency 4
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio ·5.75.76.4·6.93.98.71.75.24.86.7
Quick Ratio ·5.35.26.1·6.53.78.51.65.12.36.4
Debt / Equity ·····0.0······
LT Debt / Equity ·····0.0······
Efficiency 1
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover ·0.0···0.00.00.00.00.0··
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $1.73$2.72$2.06$9.52·$2.25$8.59$0.72$1.41$0.83$0.14$0.23
Revenue / Share ·$0.29··········
Cash Flow / Share ·$-9.03$-5.16$-10.67········
Cash / Share $1.81$3.10$2.27$10.34·$2.46$10.36$0.79$2.75$0.99$0.08$0.72
EPS (TTM) $-6.02$-9.08$-46.76$-10.10$-12.43·······
Valuation (TTM) 13
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $0$0$0$0$0$0$21.0K$138.0K$15.0K$19.0K$34.0K$399.0K
Net Income TTM $-9M$-7M$-11M$-11M$-13M$-9M$-9M$-7M$-12M$-9M$-10M$-9M
Market Cap $12M$3M$26M$46M·$1.68B$680M$36.93B$42.94B$552.26B$14.83T$11.20T
Enterprise Value ·····$1.67B······
P/E -0.2-0.2-0.1-4.0-8.7·······
P/S ······32379.5267635.72862988.029066211.3436124657.328078591.4
P/B 0.60.73.34.2·129.0118.32720.123428.750875.91667968.34081369.0
P / Tangible Book 0.60.73.34.266.7129.0······
P / Cash Flow -1.5-0.4-2.4-3.8·-190.8-78.7-4911.4-4513.9-71167.3-2026546.2-1444103.9
P / FCF -1.5-0.4-2.4-3.7·-190.4-78.0-4908.1-4419.6-71130.6-2010881.3-1426634.1
EV / EBITDA ·····-191.0······
EV / FCF ·····-188.8······
Earnings Yield -573.3%-504.4%-683.6%-25.1%-11.5%·······

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

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Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Operating Margin % · -3197.8% · · ·
Net Income $-9M $-7M $-11M $-11M $-13M
Diluted EPS · $-9.08 $-46.76 $-10.10 $-12.43

Institutional owners (13F) 25 filers · $742K total · As of June 30, 2026

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Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 25
Value held $742K
New positions 4
Exited positions 4
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
4 (-11 vs prior Q) 4 (-1 vs prior Q) 6 (+1 vs prior Q) 8 (+8 vs prior Q) -21K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
JANE STREET GROUP, LLC $120,699 117,755 16.28% Shares
GEODE CAPITAL MANAGEMENT, LLC $117,437 114,574 15.84% Shares
VANGUARD CAPITAL MANAGEMENT LLC $96,619 94,262 13.03% Shares
VANGUARD GROUP INC $92,009 87,628 12.41% Shares
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. $51,000 50,000 6.88% Shares
Cetera Investment Advisers $48,688 47,500 6.57% Shares
CITADEL ADVISORS LLC $48,329 47,150 6.52% Shares
VANGUARD FIDUCIARY TRUST CO $39,123 38,169 5.28% Shares
NORTHERN TRUST CORP $28,462 27,768 3.84% Shares
TWO SIGMA INVESTMENTS, LP $22,039 21,501 2.97% Shares
XTX Topco Ltd $18,937 18,475 2.55% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $12,300 12,000 1.66% Shares
CITIGROUP INC $11,895 11,605 1.60% Shares
CAPTRUST FINANCIAL ADVISORS $10,250 10,000 1.38% Shares
Tower Research Capital LLC (TRC) $6,361 6,206 0.86% Shares
MORGAN STANLEY $6,150 6,000 0.83% Shares
UBS Group AG $5,522 5,387 0.74% Shares
OSAIC HOLDINGS, INC. $2,060 2,000 0.28% Shares
Spire Wealth Management $2,050 1,990 0.28% Shares
SBI Securities Co., Ltd. $1,278 1,247 0.17% Shares
BARCLAYS PLC $237 231 0.03% Shares
ASSETMARK, INC $113 110 0.02% Shares
HRT FINANCIAL LP $13 13,182 0.00% Shares
Activest Wealth Management $9 9 0.00% Shares
Caitong International Asset Management Co., Ltd $6 6 0.00% Shares

Company insiders 19 insiders · 8 officers · 11 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Robert J Bitterman Chairman, Pres. & CEO Sept. 28, 2026 A 764,871 7 0 $44,860
Gerrit Dispersyn President & CEO March 1, 2022 F 212,327 0 0 $0
Lisa Cabott Carson Chief Financial Officer Sept. 28, 2026 A 189,112 0 0 $0
Robert M. Infarinato VP, CFO Sept. 11, 2024 A 11,000 0 0 $0
Caitlin Kontulis Secretary & VP Finance & Admin March 1, 2024 F 10,643 0 0 $0
John A Barrett Chief Development Officer April 22, 2019 A 222,991 0 0 $0
Alexey Eliseev Chief Business Officer Sept. 7, 2017 S 950,312 0 0 $0
Pamela Pavco Chief Development Officer Feb. 1, 2017 A 17,173 0 0 $0
Ronald Todd Plott Director Sept. 29, 2026 P 42,000 3 0 $27,450
Patricia A Bradford Director Sept. 24, 2026 P 64,151 2 0 $18,925
Jonathan E Freeman Director Feb. 5, 2026 A 32,655 0 0 $0
David H Deming Director Feb. 5, 2026 A 37,800 0 0 $0
Curtis Lockshin Director Feb. 5, 2026 A 35,155 0 0 $0
Robert L Ferrara Director Sept. 11, 2025 A 38,766 0 0 $0
Geert Cauwenbergh Director Feb. 17, 2023 A 4,235 0 0 $0
Paul H. Dorman Director Feb. 15, 2022 A 20,370 0 0 $0
Keith L Brownlie Director Feb. 13, 2019 A 20,000 0 0 $0
Advanced RNA Technologies, LLC · July 31, 2014 P 1,221,723 0 0 $0
Galena Biopharma, Inc. · May 2, 2013 S 32,393,095 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 1 ETF

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
VXF · VANGUARD INDEX FUNDS 0.00% 94,262 SH Aug. 19, 2026 Daily

PHIO Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

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rating · 7 analysts BUY
Median target $14.00 +1321.2%
2 28.6% Strong Buy
4 57.1% Buy
1 14.3% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

1 analysts · 2026-09-30

Mean target $14.00 +1321.2%

Low$14.00 Mean$14.00 High$14.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

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FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PHIO $12M -0.2 · · -57.5% ·
BIVI · · · · · ·
CNSY · · · · · ·
INTS $1M -0.0 · · -165.1% ·
GTBP $20M -0.1 · · -645.4% ·
LTRN · -1.9 · · · ·
MTVA $19M -1.1 -44.6% -2543.7% -173.5% ·

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Source: SEC 10-Q filed Aug 6, 2026