Cathy Friedman

Insider

First SEC filing: June 16, 2021 · Latest: June 12, 2026

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Insider at Companies where this person is a reporting insider.
Insider transactions Every share this person bought or sold, from Form 4 filings.
Derivatives Options and other derivative holdings reported by this person.
Initial holdings The stakes this person held when they first started reporting.

Insider at

Insider transactions

0 buys (P) 0 sells (S) Net: $0 + 25 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

25 other filings hidden

Date	Ticker	Code	Shares	Price	Value	Owned after	Δ own	A/D	vs now
June 10, 2026	LYEL	A	9,250	—	—	9,250 Direct	—	Acquired	(price as of 2026-08-20)
Sept. 8, 2023	LYEL	A	55,000	—	—	55,000 Direct	—	Acquired	(price as of 2026-08-20)
June 16, 2023	LYEL	A	65,000	—	—	65,000 Direct	—	Acquired	(price as of 2026-08-20)
June 14, 2023	SEER	A	23,443	—	—	173,574 Direct	+15.62%	Acquired	(price as of 2026-08-20)
June 14, 2023	SEER	A	34,735	—	—	34,735 Direct	—	Acquired	(price as of 2026-08-20)
June 15, 2022	SEER	A	29,640	—	—	29,640 Direct	—	Acquired	(price as of 2026-08-20)
June 15, 2022	SEER	A	9,945	—	—	150,131 Direct	+7.09%	Acquired	(price as of 2026-08-20)
June 8, 2022	LYEL	A	65,000	—	—	65,000 Direct	—	Acquired	(price as of 2026-08-20)
Dec. 14, 2021	LYEL	J	218,722	—	—	236,370 Indirect	+1239.36%	Acquired	(price as of 2026-08-20)
Dec. 14, 2021	LYEL	J	3,765,842	—	—	0 Indirect	-100.00%	Disposed	(price as of 2026-08-20)
June 21, 2021	LYEL	C	3,765,842	—	—	0 Indirect	-100.00%	Disposed	(price as of 2026-08-20)
June 21, 2021	LYEL	P	17,648	$17.00	$300,016	17,648 Indirect	—	Acquired	-95.4% (price as of 2026-08-20)
June 21, 2021	LYEL	C	3,765,842	—	—	3,765,842 Indirect	—	Acquired	(price as of 2026-08-20)
June 17, 2021	SEER	A	15,000	—	—	15,000 Direct	—	Acquired	(price as of 2026-08-20)
April 20, 2017	INVA	A	19,857	—	—	73,805 Direct	+36.81%	Acquired	(price as of 2026-08-20)
April 26, 2016	INVA	A	18,328	—	—	53,948 Direct	+51.45%	Acquired	(price as of 2026-08-20)
April 24, 2015	INVA	A	13,950	—	—	35,620 Direct	+64.37%	Acquired	(price as of 2026-08-20)
Dec. 22, 2014	INVA	A	6,500	—	—	21,670 Direct	+42.85%	Acquired	(price as of 2026-08-20)
June 2, 2014	INVA	A	7,585	—	—	7,585 Direct	—	Acquired	(price as of 2026-08-20)
June 2, 2014	INVA	A	7,585	—	—	7,585 Direct	—	Acquired	(price as of 2026-08-20)
June 2, 2014	INVA	A	7,585	—	—	15,170 Direct	+100.00%	Acquired	(price as of 2026-08-20)
June 2, 2014	INVA	A	7,585	—	—	7,585 Direct	—	Acquired	(price as of 2026-08-20)
June 2, 2014	INVA	A	6,000	—	—	6,000 Direct	—	Acquired	(price as of 2026-08-20)
June 2, 2014	INVA	A	6,000	—	—	6,000 Direct	—	Acquired	(price as of 2026-08-20)
June 2, 2014	INVA	A	6,000	—	—	12,000 Direct	+100.00%	Acquired	(price as of 2026-08-20)
June 2, 2014	INVA	A	6,000	—	—	6,000 Direct	—	Acquired	(price as of 2026-08-20)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II)

Options, RSUs and convertible securities reported on Form 4 Table II.

Date	Ticker	Security	Underlying	Exercise price	Expiration	Shares	A/D
June 10, 2026	LYEL	Option (right to buy)	Common Stock (9,250)	$13.22	June 9, 2036	9,250	Acquired
Sept. 8, 2023	LYEL	Option (right to buy) [F3]	Common Stock (55,000)	$3.19	Sept. 7, 2033	55,000	Acquired
June 16, 2023	LYEL	Option (right to buy)	Common Stock (65,000)	$3.19	June 15, 2033	65,000	Acquired
June 14, 2023	SEER	Stock Option (right to buy)	Class A Common Stock (34,735)	$4.33	June 14, 2033	34,735	Acquired
June 15, 2022	SEER	Stock Option (right to buy)	Class A Common Stock (29,640)	$7.33	June 15, 2031	29,640	Acquired
June 8, 2022	LYEL	Option (right to buy)	Common Stock (65,000)	$5.31	June 7, 2032	65,000	Acquired
June 21, 2021	LYEL	Series A Convertible Preferred Stock	Common Stock (3,765,842)	—	—	3,765,842	Disposed
June 17, 2021	SEER	Stock Option (right to buy)	Class A Common Stock (15,000)	$33.74	June 17, 2031	15,000	Acquired
June 2, 2014	INVA	Stock Option (Right to Buy)	Common Stock	$23.08	June 1, 2024	7,585	Acquired
June 2, 2014	INVA	Stock Option (Right to Buy)	Common Stock	$23.08	June 1, 2024	7,585	Acquired
June 2, 2014	INVA	Stock Option (Right to Buy)	Common Stock	$23.08	June 1, 2024	6,000	Acquired
June 2, 2014	INVA	Stock Option (Right to Buy)	Common Stock	$23.08	June 1, 2024	6,000	Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 6 holdings

Securities held when first becoming an insider, per SEC Form 3.

Date	Ticker	Security	Shares	Ownership
June 16, 2021	LYEL	Common Stock	100,000	Indirect
June 16, 2021	LYEL	Series A Convertible Preferred Stock→ Common Stock (3,765,842)	3,765,842	Indirect
June 16, 2021	LYEL	Option (right to buy)→ Common Stock (400,000)	400,000	Direct
June 16, 2021	LYEL	Option (right to buy)→ Common Stock (250,000)	250,000	Direct
Dec. 3, 2020	SEER	Class A Common Stock	140,186	Direct
March 18, 2013	NSLRL	GSVC Common Stock	0	Direct