David M Knott — SEC Insider Profile, Roles & Companies

Institution

Insider at

ARWR LGND selling Aug. 17, 2015 FF

Insider transactions

0 buys (P) 0 sells (S) Net: $0 + 11 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

11 other filings hidden

Date	Ticker	Code	Shares	Price	Value	Owned after	Δ own	A/D	vs now
April 12, 2016	1294250	S	18,013	$0.86	$15,491	260,135 Indirect	-6.48%	Disposed
April 12, 2016	1294250	S	85,840	$0.86	$73,822	397,200 Indirect	-17.77%	Disposed
April 12, 2016	1294250	S	9,400	$0.87	$8,178	278,148 Indirect	-3.27%	Disposed
April 12, 2016	1294250	S	44,600	$0.87	$38,802	483,040 Indirect	-8.45%	Disposed
April 11, 2016	1294250	S	8,549	$0.89	$7,609	287,548 Indirect	-2.89%	Disposed
April 11, 2016	1294250	S	40,900	$0.89	$36,401	527,640 Indirect	-7.19%	Disposed
April 8, 2016	1294250	S	538	$0.93	$500	296,097 Indirect	-0.18%	Disposed
April 8, 2016	1294250	S	2,160	$0.93	$2,009	568,540 Indirect	-0.38%	Disposed
March 10, 2016	1294250	J	3,580	·	·	0 Indirect	-100.00%	Disposed
Dec. 22, 2015	1294250	S	3,897	$1.51	$5,884	296,635 Indirect	-1.30%	Disposed
Dec. 22, 2015	1294250	S	19,300	$1.51	$29,143	570,700 Indirect	-3.27%	Disposed
Dec. 21, 2015	1294250	S	37,000	$1.55	$57,350	590,000 Indirect	-5.90%	Disposed
Dec. 21, 2015	1294250	S	7,364	$1.55	$11,414	300,532 Indirect	-2.39%	Disposed
Dec. 18, 2015	1294250	S	11,798	$1.57	$18,523	307,896 Indirect	-3.69%	Disposed
Dec. 18, 2015	1294250	S	57,600	$1.57	$90,432	627,000 Indirect	-8.41%	Disposed
Dec. 17, 2015	1294250	S	3,400	$1.56	$5,304	319,694 Indirect	-1.05%	Disposed
Dec. 17, 2015	1294250	S	16,700	$1.56	$26,052	684,600 Indirect	-2.38%	Disposed
Dec. 16, 2015	1294250	S	4,871	$1.76	$8,573	323,094 Indirect	-1.49%	Disposed
Dec. 16, 2015	1294250	S	23,800	$1.76	$41,888	701,300 Indirect	-3.28%	Disposed
Dec. 15, 2015	1294250	S	6,401	$1.83	$11,714	327,965 Indirect	-1.91%	Disposed
Dec. 15, 2015	1294250	S	31,900	$1.83	$58,377	725,100 Indirect	-4.21%	Disposed
Dec. 14, 2015	1294250	S	5,769	$1.90	$10,961	334,366 Indirect	-1.70%	Disposed
Dec. 14, 2015	1294250	S	20,200	$1.90	$38,380	757,000 Indirect	-2.60%	Disposed
Nov. 17, 2015	1294250	J	940	·	·	0 Indirect	-100.00%	Disposed
Aug. 17, 2015	LGND	S	4,000	$95.98	$383,920	66,152 Direct	-5.70%	Disposed	406.0% (price as of 2026-10-02)
Aug. 13, 2015	LGND	S	7,225	$96.20	$695,045	30,771 Indirect	-19.02%	Disposed	404.8% (price as of 2026-10-02)
Aug. 13, 2015	LGND	S	27,300	$96.20	$2,626,260	196,186 Indirect	-12.22%	Disposed	404.8% (price as of 2026-10-02)
Aug. 13, 2015	LGND	S	2,000	$96.20	$192,400	969,300 Indirect	-0.21%	Disposed	404.8% (price as of 2026-10-02)
Aug. 12, 2015	LGND	S	2,600	$96.45	$250,770	37,996 Indirect	-6.40%	Disposed	403.5% (price as of 2026-10-02)
Aug. 12, 2015	LGND	S	9,875	$96.45	$952,444	223,486 Indirect	-4.23%	Disposed	403.5% (price as of 2026-10-02)
Aug. 12, 2015	LGND	S	800	$96.45	$77,160	971,300 Indirect	-0.08%	Disposed	403.5% (price as of 2026-10-02)
Aug. 7, 2015	LGND	S	200	$99.02	$19,804	40,596 Indirect	-0.49%	Disposed	390.5% (price as of 2026-10-02)
July 23, 2015	1294250	S	1,200	$3.08	$3,696	340,135 Indirect	-0.35%	Disposed
July 23, 2015	1294250	S	6,100	$3.08	$18,788	777,200 Indirect	-0.78%	Disposed
July 20, 2015	1294250	S	900	$3.17	$2,853	341,335 Indirect	-0.26%	Disposed
July 20, 2015	1294250	S	4,100	$3.17	$12,997	783,300 Indirect	-0.52%	Disposed
July 17, 2015	1294250	S	2,500	$3.18	$7,950	342,235 Indirect	-0.73%	Disposed
July 17, 2015	1294250	S	12,500	$3.18	$39,750	787,400 Indirect	-1.56%	Disposed
July 15, 2015	1294250	S	15,700	$3.17	$49,769	799,900 Indirect	-1.92%	Disposed
July 15, 2015	1294250	S	2,403	$3.17	$7,618	344,735 Indirect	-0.69%	Disposed
July 13, 2015	1294250	S	800	$3.22	$2,576	347,138 Indirect	-0.23%	Disposed
July 13, 2015	1294250	S	4,200	$3.22	$13,524	815,600 Indirect	-0.51%	Disposed
July 10, 2015	1294250	S	2,000	$3.24	$6,480	347,938 Indirect	-0.57%	Disposed
July 10, 2015	1294250	S	13,100	$3.24	$42,444	819,800 Indirect	-1.57%	Disposed
July 9, 2015	1294250	S	30,000	$3.18	$95,400	349,938 Indirect	-7.90%	Disposed
July 8, 2015	1294250	S	8,100	$3.18	$25,758	379,938 Indirect	-2.09%	Disposed
July 7, 2015	1294250	S	200	$3.25	$650	388,038 Indirect	-0.05%	Disposed
June 26, 2015	1294250	S	4,954	$3.25	$16,100	388,238 Indirect	-1.26%	Disposed
June 25, 2015	1294250	S	10,000	$3.28	$32,800	393,192 Indirect	-2.48%	Disposed
June 22, 2015	1294250	S	1,839	$3.35	$6,161	403,192 Indirect	-0.45%	Disposed
June 19, 2015	1294250	S	3,847	$3.30	$12,695	405,031 Indirect	-0.94%	Disposed
June 18, 2015	1294250	S	16,916	$3.31	$55,992	408,878 Indirect	-3.97%	Disposed
June 17, 2015	1294250	S	2,733	$3.40	$9,292	425,794 Indirect	-0.64%	Disposed
June 15, 2015	1294250	S	11,340	$3.38	$38,329	428,527 Indirect	-2.58%	Disposed
June 12, 2015	1294250	S	10,000	$3.36	$33,600	439,867 Indirect	-2.22%	Disposed
April 24, 2015	LGND	A	2,754	·	·	2,754 Direct	·	Acquired	(price as of 2026-10-02)
April 24, 2015	LGND	A	925	·	·	70,152 Direct	+1.34%	Acquired	(price as of 2026-10-02)
Feb. 23, 2015	1294250	S	4,600	$3.51	$16,146	449,867 Indirect	-1.01%	Disposed
Feb. 19, 2015	1294250	S	7,890	$3.51	$27,694	454,467 Indirect	-1.71%	Disposed
Feb. 18, 2015	1294250	S	28,600	$3.52	$100,672	462,357 Indirect	-5.83%	Disposed
Feb. 17, 2015	1294250	S	30,000	$3.53	$105,900	490,957 Indirect	-5.76%	Disposed
Feb. 13, 2015	1294250	S	57,501	$3.63	$208,729	520,957 Indirect	-9.94%	Disposed
Dec. 29, 2014	1294250	S	2,923	$3.91	$11,429	578,458 Indirect	-0.50%	Disposed
Dec. 8, 2014	1294250	S	4,500	$4.35	$19,575	581,381 Indirect	-0.77%	Disposed
Dec. 5, 2014	1294250	S	15,876	$4.44	$70,489	585,881 Indirect	-2.64%	Disposed
Oct. 9, 2014	LGND	P	4,000	$43.01	$172,040	69,227 Direct	+6.13%	Acquired	1029.1% (price as of 2026-10-02)
Oct. 9, 2014	LGND	A	4,000	$43.01	$172,040	69,227 Direct	+6.13%	Acquired	1029.1% (price as of 2026-10-02)
June 4, 2014	LGND	A	3,312	·	·	3,312 Direct	·	Acquired	(price as of 2026-10-02)
June 4, 2014	LGND	A	1,484	·	·	65,227 Direct	+2.33%	Acquired	(price as of 2026-10-02)
Feb. 20, 2014	LGND	S	900	$72.97	$65,673	1,843 Indirect	-32.81%	Disposed	565.5% (price as of 2026-10-02)
Feb. 18, 2014	LGND	S	3,900	$73.31	$285,909	40,796 Indirect	-8.73%	Disposed	562.5% (price as of 2026-10-02)
Feb. 18, 2014	LGND	S	11,531	$73.31	$845,338	233,361 Indirect	-4.71%	Disposed	562.5% (price as of 2026-10-02)
Feb. 14, 2014	LGND	S	6,700	$77.10	$516,570	44,696 Indirect	-13.04%	Disposed	529.9% (price as of 2026-10-02)
Feb. 14, 2014	LGND	S	19,769	$77.10	$1,524,190	244,892 Indirect	-7.47%	Disposed	529.9% (price as of 2026-10-02)
Oct. 2, 2013	1294250	S	18,057	$4.84	$87,396	0 Indirect	-100.00%	Disposed
Oct. 2, 2013	1294250	S	18,651	$4.84	$90,271	601,757 Indirect	-3.01%	Disposed
Oct. 1, 2013	1294250	S	8,792	$4.85	$42,641	18,057 Indirect	-32.75%	Disposed
Oct. 1, 2013	1294250	S	9,000	$4.85	$43,650	620,408 Indirect	-1.43%	Disposed
Sept. 30, 2013	1294250	S	39,400	$4.86	$191,484	26,849 Indirect	-59.47%	Disposed
Sept. 30, 2013	1294250	S	40,600	$4.86	$197,316	629,408 Indirect	-6.06%	Disposed
Sept. 27, 2013	1294250	S	200	$5.00	$1,000	66,249 Indirect	-0.30%	Disposed
Sept. 27, 2013	1294250	S	300	$5.00	$1,500	670,008 Indirect	-0.04%	Disposed
Sept. 26, 2013	1294250	S	19,700	$5.00	$98,500	66,449 Indirect	-22.87%	Disposed
Sept. 26, 2013	1294250	S	20,300	$5.00	$101,500	670,308 Indirect	-2.94%	Disposed
Sept. 12, 2013	LGND	S	160,000	$46.78	$7,484,800	51,396 Indirect	-75.69%	Disposed	938.1% (price as of 2026-10-02)
June 17, 2013	1294250	S	128,942	$5.50	$709,181	86,149 Indirect	-59.95%	Disposed
June 14, 2013	1294250	S	25,000	$5.50	$137,500	215,091 Indirect	-10.41%	Disposed
June 14, 2013	1294250	S	21,058	$5.50	$115,819	240,091 Indirect	-8.06%	Disposed
June 11, 2013	LGND	A	7,335	·	·	7,335 Direct	·	Acquired	(price as of 2026-10-02)
June 11, 2013	LGND	A	4,318	·	·	63,743 Direct	+7.27%	Acquired	(price as of 2026-10-02)
Feb. 22, 2013	1294250	S	7,834	$6.00	$47,004	261,149 Indirect	-2.91%	Disposed
Feb. 21, 2013	1294250	S	5,040	$6.00	$30,240	268,983 Indirect	-1.84%	Disposed
Feb. 7, 2013	1294250	S	1,161	$6.51	$7,558	274,023 Indirect	-0.42%	Disposed
Feb. 6, 2013	1294250	S	10,000	$6.64	$66,400	275,184 Indirect	-3.51%	Disposed
Feb. 5, 2013	1294250	S	10,000	$6.55	$65,500	285,184 Indirect	-3.39%	Disposed
Feb. 4, 2013	1294250	S	20,832	$6.61	$137,700	295,184 Indirect	-6.59%	Disposed
Feb. 1, 2013	1294250	S	10,000	$6.70	$67,000	316,016 Indirect	-3.07%	Disposed
Jan. 31, 2013	1294250	S	5,001	$6.95	$34,757	326,016 Indirect	-1.51%	Disposed
Jan. 30, 2013	1361872	U	30,372	$6.70	$203,492	0 Indirect	-100.00%	Disposed
Jan. 30, 2013	1361872	U	2,783	$6.70	$18,646	0 Indirect	-100.00%	Disposed

Showing latest 100 of 693 transactions

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

Date	Ticker	Security	Underlying	Exercise price	Expiration	Shares	A/D
March 10, 2016	1294250	Series A Convertible Preferred Stock	Common Stock (28,870)	$6.20	·	3,580	Disposed
Nov. 17, 2015	1294250	Series A Convertible Preferred Stock	Common Stock (7,580)	$6.20	·	940	Disposed
April 24, 2015	LGND	Non-Qualified Stock Option (right to buy) [F5]	Common Stock (2,754)	$89.75	April 24, 2025	2,754	Acquired
June 4, 2014	LGND	Non-Qualified Stock Option (right to buy) [F5]	Common Stock (3,312)	$67.53	June 4, 2024	3,312	Acquired
June 11, 2013	LGND	Non-Qualified Stock Option (right to buy) [F5]	Common Stock (7,335)	$32.30	June 11, 2023	7,335	Acquired
May 31, 2012	LGND	Non-Qualified Stock Option (right to buy) [F5]	Common Stock (7,335)	$12.53	May 31, 2022	7,335	Acquired
June 1, 2011	LGND	Non-Qualified Stock Option (right to buy) [F1,F8,F9]	Common Stock (7,335)	$10.12	June 1, 2021	7,335	Acquired
Feb. 15, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (13,600)	$5.00	March 4, 2011	13,600	Disposed
Feb. 15, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (193,902)	$5.00	March 4, 2011	193,902	Disposed
Feb. 15, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (71,700)	$5.00	March 4, 2011	71,700	Disposed
Feb. 15, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (244,800)	$5.00	March 4, 2011	244,800	Disposed
Feb. 11, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (233,700)	$5.00	March 4, 2011	233,700	Disposed
Feb. 11, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (68,400)	$5.00	March 4, 2011	68,400	Disposed
Feb. 11, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (185,000)	$5.00	March 4, 2011	185,000	Disposed
Feb. 11, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (12,900)	$5.00	March 4, 2011	12,900	Disposed
Feb. 8, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (25,800)	$5.00	March 4, 2011	25,800	Disposed
Feb. 8, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (2)	$5.00	March 4, 2011	2	Disposed
Feb. 8, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (370,198)	$5.00	March 4, 2011	370,198	Disposed
Feb. 8, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (136,700)	$5.00	March 4, 2011	136,700	Disposed
Feb. 8, 2011	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (467,300)	$5.00	March 4, 2011	467,300	Disposed
Nov. 19, 2010	LGND	Non-Qualified Stock Option (right to buy) [F1]	Common Stock (3,333)	$53.34	March 1, 2017	3,333	Acquired
Nov. 19, 2010	LGND	Non-Qualified Stock Option (right to buy) [F1]	Common Stock (20,000)	$8.89	March 1, 2017	20,000	Disposed
Nov. 19, 2010	LGND	Non-Qualified Stock Option (right to buy) [F1]	Common Stock (2,500)	$17.88	May 29, 2019	2,500	Acquired
Nov. 19, 2010	LGND	Non-Qualified Stock Option (right to buy) [F1]	Common Stock (15,000)	$2.98	May 29, 2019	15,000	Disposed
Nov. 19, 2010	LGND	Non-Qualified Stock Option (right to buy) [F1]	Common Stock (2,500)	$8.58	May 25, 2020	2,500	Acquired
Nov. 19, 2010	LGND	Non-Qualified Stock Option (right to buy) [F1]	Common Stock (15,000)	$1.43	May 25, 2020	15,000	Disposed
Sept. 22, 2010	1361872	Class A Common Stock Warrants (right to buy)	Class A Common Stock (23,169)	$5.00	May 24, 2011	23,169	Disposed
July 7, 2010	FF	Warrants to purchase one share of Common Stock [F1]	Common Stock (70,600)	$6.00	July 12, 2010	70,600	Disposed
July 7, 2010	FF	Warrants to purchase one share of Common Stock [F1]	Common Stock (454,200)	$6.00	July 12, 2010	454,200	Disposed
July 7, 2010	FF	Warrants to purchase one share of Common Stock [F1]	Common Stock (355,300)	$6.00	July 12, 2010	355,300	Disposed
July 7, 2010	FF	Warrants to purchase one share of Common Stock [F1]	Common Stock (883,800)	$6.00	July 12, 2010	883,800	Disposed
July 1, 2010	1331931	Convertible Note	Common Stock	$10.00	Jan. 21, 2013	1,000	Disposed
July 1, 2010	1331931	Convertible Note	Common Stock	$10.00	Jan. 21, 2013	8,000	Disposed
July 1, 2010	1331931	Convertible Note	Common Stock	$10.00	Jan. 21, 2013	4,000	Disposed
July 1, 2010	1331931	Convertible Note	Common Stock	$10.00	Jan. 21, 2013	7,000	Disposed
July 1, 2010	1331931	Convertible Note	Common Stock	$10.00	Jan. 21, 2013	30,000	Disposed
July 1, 2010	1331931	Warrants to purchase one share of Common Stock	Common Stock	$0.10	Jan. 21, 2016	23,077	Disposed
July 1, 2010	1331931	Warrants to purchase one share of Common Stock	Common Stock	$0.10	Jan. 21, 2016	184,615	Disposed
July 1, 2010	1331931	Warrants to purchase one share of Common Stock	Common Stock	$0.10	Jan. 21, 2016	92,308	Disposed
July 1, 2010	1331931	Warrants to purchase one share of Common Stock	Common Stock	$0.10	Jan. 21, 2016	161,538	Disposed
July 1, 2010	1331931	Warrants to purchase one share of Common Stock	Common Stock	$0.10	Jan. 21, 2016	692,308	Disposed
June 28, 2010	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	15,300	Disposed
June 28, 2010	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	100,698	Disposed
May 25, 2010	LGND	Non-Qualified Stock Option (right to buy)	Common Stock (15,000)	$1.43	May 25, 2011	15,000	Acquired
April 19, 2010	1331931	Option to purchase Common Stock	Common Stock (5,480)	$0.00	March 22, 2010	5,480	Disposed
April 19, 2010	1331931	Option to purchase Common Stock	Common Stock (8,996)	$0.00	March 22, 2010	8,996	Disposed
April 19, 2010	1331931	Option to purchase Common Stock	Common Stock (2,991)	$0.00	March 22, 2010	2,991	Disposed
April 19, 2010	1331931	Option to purchase Common Stock	Common Stock (97,621)	$0.00	March 22, 2010	97,621	Disposed
April 19, 2010	1331931	Option to purchase Common Stock	Common Stock (1,048)	$0.00	March 22, 2010	1,048	Disposed
April 19, 2010	1331931	Option to purchase Common Stock	Common Stock (47,752)	$0.00	March 22, 2010	47,752	Disposed
April 19, 2010	1331931	Option to purchase Common Stock	Common Stock (57,687)	$0.00	March 22, 2010	57,687	Disposed
Oct. 16, 2009	1361872	Class A Common Stock Warrants (right to buy)	Class A Common Stock (23,169)	$5.00	May 24, 2011	23,169	Acquired
May 29, 2009	LGND	Non-Qualified Stock Option (right to buy)	Common Stock (15,000)	$2.98	May 29, 2010	15,000	Acquired
Dec. 19, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock	$6.00	July 12, 2010	406,600	Disposed
Dec. 19, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock	$6.00	July 12, 2010	27,600	Acquired
Dec. 19, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock	$6.00	July 12, 2010	58,700	Acquired
Dec. 19, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock	$6.00	July 12, 2010	320,300	Acquired
Nov. 26, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	48,900	Disposed
Nov. 26, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	22,400	Acquired
Nov. 26, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	35,200	Acquired
Oct. 31, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	62,000	Acquired
Oct. 31, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	4,900	Acquired
Oct. 31, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	768,500	Acquired
Oct. 31, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	496,300	Acquired
Oct. 31, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	808,300	Acquired
July 17, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock (195,200)	$6.00	July 12, 2010	195,200	Acquired
July 17, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock (115,900)	$6.00	July 12, 2010	115,900	Acquired
July 17, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock (188,900)	$6.00	July 12, 2010	188,900	Acquired
July 16, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock (16,900)	$6.00	July 12, 2010	16,900	Acquired
July 16, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock (9,900)	$6.00	July 12, 2010	9,900	Acquired
July 16, 2008	FF	Common Stock Warrants (right to buy) [F1]	Common Stock (16,200)	$6.00	July 12, 2010	16,200	Acquired
July 7, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	3,900	Disposed
July 7, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	3,900	Acquired
July 2, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	8,000	Disposed
July 2, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	700	Disposed
July 2, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	57,900	Acquired
July 2, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	34,600	Acquired
July 2, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	57,300	Disposed
July 2, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	37,300	Disposed
July 2, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock	$5.00	March 4, 2011	2,100	Acquired
June 17, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (3,400)	$5.00	March 4, 2011	3,400	Acquired
June 17, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (58,100)	$5.00	March 4, 2011	58,100	Acquired
June 17, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (98,500)	$5.00	March 4, 2011	98,500	Acquired
June 16, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (500)	$5.00	March 4, 2011	500	Acquired
June 16, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (9,000)	$5.00	March 4, 2011	9,000	Acquired
June 16, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (15,500)	$5.00	March 4, 2011	15,500	Acquired
May 9, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (1,700)	$5.00	March 4, 2011	1,700	Acquired
May 9, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (45,400)	$5.00	March 4, 2011	45,400	Acquired
May 9, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (102,900)	$5.00	March 4, 2011	102,900	Acquired
April 17, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (533,500)	$5.00	March 4, 2011	20,000	Acquired
April 17, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (345,300)	$5.00	March 4, 2011	7,600	Acquired
April 17, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (4,900)	$5.00	March 4, 2011	300	Acquired
April 17, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (95,500)	$5.00	March 4, 2011	2,100	Acquired
April 14, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (93,400)	$5.00	March 4, 2011	2,100	Acquired
April 14, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (4,600)	$5.00	March 4, 2011	200	Acquired
April 14, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (337,700)	$5.00	March 4, 2011	7,200	Acquired
April 14, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (513,500)	$5.00	March 4, 2011	20,500	Acquired
March 18, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (3,850)	$5.00	March 4, 2011	3,850	Disposed
March 18, 2008	1373988	Common Stock Warrants (right to buy) [F1]	Common Stock (7,150)	$5.00	March 4, 2011	7,150	Disposed
May 3, 2007	1373988	Common Stock Warrants (right to buy)(1)	Common Stock (165,200)	$5.00	March 4, 2011	165,200	Disposed

Showing latest 100 of 171 transactions

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 46 holdings

Securities held when first becoming an insider, per SEC Form 3.

Date	Ticker	Security	Shares	Ownership
July 18, 2008	FF	Common Stock, $.0001 par value per share [F1]	547,100	Indirect
July 18, 2008	FF	Common Stock, $.0001 par value per share [F1]	325,800	Indirect
July 18, 2008	FF	Common Stock, $.0001 par value per share [F1]	7,900	Indirect
July 18, 2008	FF	Common Stock, $.0001 par value per share [F1]	752,550	Indirect
July 18, 2008	FF	Common Stock, $.0001 par value per share [F1]	44,800	Indirect
July 18, 2008	FF	Warrants to purchase one share of Common Stock [F1]→ Common Stock (358,400)	358,400	Indirect
July 18, 2008	FF	Warrants to purchase one share of Common Stock [F1]→ Common Stock (229,500)	229,500	Indirect
July 18, 2008	FF	Warrants to purchase one share of Common Stock [F1]→ Common Stock (183,400)	183,400	Indirect
July 18, 2008	FF	Warrants to purchase one share of Common Stock [F1]→ Common Stock (449,600)	449,600	Indirect
Nov. 20, 2007	DYAI	Common Stock, $0.001 par value per share	·	Indirect
Nov. 20, 2007	DYAI	Common Stock, $0.001 par value per share	·	Indirect
Nov. 20, 2007	DYAI	Common Stock, $0.001 par value per share	·	Indirect
Nov. 20, 2007	DYAI	Common Stock, $0.001 par value per share	·	Indirect
Nov. 20, 2007	DYAI	Common Stock, $0.001 par value per share	·	Indirect
Nov. 20, 2007	DYAI	Common Stock, $0.001 par value per share	·	Indirect
Nov. 20, 2007	DYAI	Common Stock, $0.001 par value per share	·	Indirect
March 9, 2007	LGND	Common Stock	2,419,383	Indirect
March 9, 2007	LGND	Common Stock	1,326,841	Indirect
March 9, 2007	LGND	Common Stock	18,400	Indirect
March 9, 2007	LGND	Common Stock	3,929,331	Indirect
March 9, 2007	LGND	Common Stock	259,184	Indirect
March 9, 2007	LGND	Common Stock	32,400	Indirect
March 9, 2007	LGND	Common Stock	547,518	Indirect
Oct. 25, 2006	LGND	Common Stock	2,271,000	Indirect
Oct. 25, 2006	LGND	Common Stock	1,256,700	Indirect
Oct. 25, 2006	LGND	Common Stock	18,400	Indirect
Oct. 25, 2006	LGND	Common Stock	3,788,400	Indirect
Oct. 25, 2006	LGND	Common Stock	32,400	Indirect
Oct. 25, 2006	LGND	Common Stock	448,700	Indirect
Oct. 25, 2006	LGND	6% Convertible Subordinated Notes due 2007→ Common Stock (148,383)	148,383	Indirect
Oct. 25, 2006	LGND	6% Convertible Subordinated Notes due 2007→ Common Stock (70,141)	70,141	Indirect
Oct. 25, 2006	LGND	6% Convertible Subordinated Notes due 2007→ Common Stock (140,931)	140,931	Indirect
Oct. 25, 2006	LGND	6% Convertible Subordinated Notes due 2007→ Common Stock (259,184)	259,184	Indirect
Oct. 25, 2006	LGND	6% Convertible Subordinated Notes due 2007→ Common Stock (29,318)	29,318	Indirect
Jan. 30, 2006	ARWR	Common stock, $0.001 par value per share	40,300	Indirect
Jan. 30, 2006	ARWR	Common stock, $0.001 par value per share	160,200	Indirect
Jan. 30, 2006	ARWR	Common stock, $0.001 par value per share	45,600	Indirect
Jan. 30, 2006	ARWR	Common stock, $0.001 par value per share	1,330,500	Indirect
Jan. 30, 2006	ARWR	Common stock, $0.001 par value per share	1,739,181	Indirect
Jan. 30, 2006	ARWR	Common stock, $0.001 par value per share	733,800	Indirect
Jan. 30, 2006	ARWR	Warrant to purchase Common Stock, $0.001 par value per share→ Common Stock, $0.001 par value per share (3,075)	3,075	Indirect
Jan. 30, 2006	ARWR	Warrant to purchase Common Stock, $0.001 par value per share→ Common Stock, $0.001 par value per share (12,075)	12,075	Indirect
Jan. 30, 2006	ARWR	Warrant to purchase Common Stock, $0.001 par value per share→ Common Stock, $0.001 par value per share (3,450)	3,450	Indirect
Jan. 30, 2006	ARWR	Warrant to purchase Common Stock, $0.001 par value per share→ Common Stock, $0.001 par value per share (108,475)	108,475	Indirect
Jan. 30, 2006	ARWR	Warrant to purchase Common Stock, $0.001 par value per share→ Common Stock, $0.001 par value per share (161,688)	161,688	Indirect
Jan. 30, 2006	ARWR	Warrant to purchase Common Stock, $0.001 par value per share→ Common Stock, $0.001 par value per share (68,400)	68,400	Indirect