your badges 52W Range $35–$95 49% of range Analyst Rating BUY 20 analysts Price Target $107 +67% upside P/E -29.4 ROE -64.8% Net Profit Margin -47.8%

ARWR Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $64.19
Market Cap (MRQ) $9.06B
P/E (TTM) -29.4
EPS (TTM) $-2.18
Revenue (TTM) $669M
ROE (TTM) -64.8%
52W Range $35–$95

ARWR Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
range
bars

Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.

Stock splits 2
Ex-date Split Type
Nov. 17, 2011 1-for-10 Reverse
Jan. 15, 2004 1-for-65 Reverse

About Arrowhead Pharmaceuticals, Inc. - Common Stock Company overview from Wikipedia

05 · wikidata
sectorHealthcare industryBiotechnology employees711 countryUS

10-Year Performance Revenue, net income, margins and EPS trends

06
Revenue$829M
2016-09-30 → 2025-09-30
EPS$-0.01
2017-09-30 → 2025-09-30
Free Cash Flow$157M
2016-09-30 → 2025-09-30
Net margin-47.8%
2016-09-30 → 2025-09-30
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend ARWR 5Y avg Peer Median Verdict
P/E (TTM) -29.45Y avg ≈-706.5 ≈-706.5 · ·
P/S (TTM) 13.55Y avg ≈19.8 ≈19.8 26.5 Undervalued
P/B (MRQ) 19.55Y avg ≈11.3 ≈11.3 8.5 Overvalued
Price / FCF (TTM) -120.65Y avg ≈11.7 ≈11.7 · ·
Price / Cash Flow (TTM) -153.45Y avg ≈4.9 ≈4.9 63.7 Undervalued
Price / Tangible Book (MRQ) 19.75Y avg ≈12.1 ≈12.1 · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 245.8%
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 6, 2026 $-1.36 $-1.35 -1.0%
March 31, 2026 $-0.93 $-1.21 23.2%
Dec. 31, 2025 $0.22 $0.26 -14.8%
Sept. 30, 2025 $-0.18 $-0.25 26.7%
June 30, 2025 $-1.26 $-1.05 -20.5%
March 31, 2025 $2.75 $-0.20 1461.4%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 15
Metric Trend 202520242023202220212020201920182017201620152014
Revenue $829M$4M$241M$243M$138M$88M$169M$16M$31M$158.3K$382.0K$175.0K
R&D Expense $607M$506M$353M·······$47M$23M
SG&A Expense $124M$99M$93M$124M$81M$52M$27M$19M$17M$24M$8M$6M
Operating Expenses $731M$605M$446M$422M$287M$181M$108M$72M$68M$82M$96M$53M
Operating Income $98M$-601M$-205M$-179M$-149M$-93M$61M$-56M$-37M$-82M$-96M$-53M
Interest Expense ··$18M$0$0·······
Other Non-op $5M$-2M$2M$765.0K$2M$-583.0K·$7.5K$1M$57.4K$417.9K$82.1K
Pretax Income $52M$-612M$-206M$-173M$-141M$-85M$68M$-54M$-34M$-82M$-92M$-59M
Income Tax $21M$-3M$3M$4M$2.0K$2.0K$174.0K$2.4K$2.4K$2.4K$2.4K$5.3K
Net Income $-2M$-599M$-205M$-176M$-141M$-85M$68M$-54M$-34M$-82M$-92M$-59M
EPS (Basic) $-0.01$-5.00$-1.92$-1.67$-1.36$-0.84$0.72$-0.65$-0.47···
EPS (Diluted) $-0.01$-5.00$-1.92$-1.67$-1.36$-0.84$0.69$-0.65$-0.47···
Shares (Basic) 133,758,000119,784,000106,750,000105,426,000103,745,000100,722,00093,859,00083,638,46973,898,598···
Shares (Diluted) 133,758,000119,784,000106,750,000105,426,000103,745,000100,722,00098,608,00083,638,46973,898,598···
EBITDA $121M·$-194M$-170M$-142M$-89M$64M$-56M$-37M$-82M$-96M$-52M
Balance Sheet 27
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents ····$184M$144M$222M$30M$25M$85M$81M$133M
Short-term Investments $693M··$0$127M$85M·····$22M
Receivables $7M$0$0$1M$10M$846.0K$661.4K$327.4K$67.8K$75.0K··
Prepaid Expense $11M$10M$9M$7M$4M$4M$3M$1M$867.4K$1M$3M$588.6K
Other Current Assets $14M$5M$4M$20M$2M$2M$3M$640.1K$1M$4M$823.6K$48.5K
Current Assets $951M$695M$416M$405M$385M$322M$265M$79M$68M$91M$103M$155M
PP&E (Net) $383M$386M$290M$110M$49M$31M$23M$14M$16M$15M$5M$4M
PP&E (Gross) $463M$444M$332M$142M$72M$47M$35M$24M$23M$20M$10M$8M
Accum. Depreciation $80M$58M$42M$32M$23M$16M$12M$10M$7M$5M$5M$4M
Intangibles $7M$9M$10M$12M$14M$15M$17M$19M$20M$22M$25M$1M
Other Non-current Assets $1M$4M$3M$218.0K$272.0K$264.0K$144.1K$141.9K$141.9K$122.3K$45.8K·
Total Assets $1.39B$1.14B$766M$692M$710M$523M$350M$112M$104M$128M$132M$183M
Accounts Payable $18M$11M$36M$3M$9M$7M$8M$3M$4M$12M$5M$3M
Accrued Liabilities $90M$63M$40M$47M$14M$5M$7M$5M$5M$5M$5M$1M
Short-term Debt ·······$223.8K$208.5K$194.3K·$50.0K
Current Liabilities $195M$103M$105M$139M$147M$41M$97M$12M$19M$26M$16M$12M
Capital Leases $104M$111M$105M$79M$23M$20M····$540.8K$758.3K
Other Non-current Liabilities ···$0···$200.0K$200.0K$200.0K$200.0K$255.2K
Total Debt ·······$223.8K$208.5K$194.3K·$50.0K
Common Stock $231.0K$217.0K$200.0K$198.0K$197.0K$195.0K$187.9K$180.9K$167.2K$162.1K$151.9K$147.0K
Paid-in Capital ·······$583M$514M$494M$427M$391M
Retained Earnings $-1.63B$-1.63B$-1.03B$-821M$-645M$-504M$-419M$-487M$-433M$-398M$-317M$-225M
Treasury Stock $53M$0··········
AOCI $6M$5M$-3M$-136.0K$-69.0K$18.0K$-391.6K$-21.6K$33.2K$7.4K$-136.4K·
Stockholders' Equity $466M$185M$271M$399M$409M$462M$244M$95M$81M$96M$110M$167M
Liabilities + Equity $1.39B$1.14B$766M$692M$710M$523M$350M$112M$104M$128M$132M$183M
Shares Outstanding 135,702,000124,376,000107,312,000105,960,000104,327,000102,376,00095,506,27188,505,30274,785,72669,746,68559,544,67754,656,936
Cash Flow 15
Metric Trend 202520242023202220212020201920182017201620152014
D&A $22M$17M$11M$9M$7M$4M$3M$3M$3M$3M$2M$1M
Stock-based Comp $63M$74M$78M$121M$77M$43M$12M$8M$8M$12M$10M$6M
Deferred Tax $0$0$0$0$0·······
Amort. of Intangibles $2M$2M$2M$2M$2M$2M$2M$2M$2M$2M$1M$54.7K
Other Non-cash $96M·$-37M$-90M$229M$-58M$90M····$16M
Operating Cash Flow $180M$-463M$-154M$-136M$171M$-96M$173M$-47M$-24M$-64M$-66M$-35M
CapEx $23M$141M$177M$53M$24M$12M$12M$1M$8M$4M$2M$2M
Investing Cash Flow $-129M$-420M$-96M$-5M$-142M$-241M$-48M$-7M$-49M$13M··
Stock Issued $241M$429M$0$0$0$250M$61M$57M$12M$52M·$173M
Net Stock Activity $241M··$0·$250M$61M$57M$12M$52M··
Financing Cash Flow $74M$871M$253M$65M$11M$258M$66M$60M$12M$55M··
Net Change in Cash ····$41M$-78M$192M$5M$-61M$4M$-51M$113M
Taxes Paid $814.0K$-4M$0$-2.0K$-2.0K$103.0K$-302.0K$-2.4K····
Free Cash Flow $157M·$-331M$-189M$148M$-107M$161M$-49M$-32M$-68M$-68M$-37M
Levered FCF ··$-349M·········
Profitability 7
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 11.9%·-85.2%-73.4%-107.8%-105.9%36.2%-346.5%-117.8%-51627.1%-25124.1%-30443.6%
Net Margin -0.20%·-85.3%-72.4%-101.8%-96.1%40.3%-337.3%·-51614.6%-24068.3%-33503.0%
Pretax Margin 6.2%·-85.8%-71.0%-101.8%-96.1%40.4%-337.3%-109.5%-51613.1%-24067.7%-33554.3%
EBITDA Margin 14.5%·-80.7%-69.8%-103.0%-101.0%37.9%-346.5%-117.8%-51627.1%-25124.1%-29674.7%
ROA -0.13%·-28.2%-25.1%-22.9%-19.4%29.5%-50.5%·-62.8%-58.4%-53.3%
ROE -0.50%·-61.3%-45.7%-33.0%-17.7%40.0%-61.5%·-79.4%-66.5%-60.4%
ROIC 12.3%·-76.6%-45.8%-36.5%-20.2%24.9%-58.3%-45.3%-85.4%-87.1%-32.0%
Liquidity & Solvency 4
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 4.9·4.02.92.67.92.76.43.63.56.513.1
Quick Ratio 0.0·0.00.02.25.62.32.51.33.35.113.0
Debt / Equity ·······0.00.00.0·0.0
Interest Coverage ··-11.2·········
Efficiency 2
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 0.7·0.30.30.20.20.70.10.30.00.00.0
Receivables Turnover 243.1·341.541.724.9116.8341.481.7439.92.1··
Per Share 5
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share $3.43·$2.53$3.76$3.92$4.51$2.56$1.08$1.09$1.37$1.85$3.05
Revenue / Share $6.20·$2.26$2.31$1.33$0.87$1.71·····
Cash Flow / Share $1.34·$-1.44$-1.29$1.65$-0.95$1.75·····
Cash / Share ····$1.77$1.40$2.32$0.34$0.33$1.22$1.36$2.42
EPS (TTM) $-0.01$-5.00$-1.92$-1.67$-1.36$-0.84$0.69$-0.65$-0.47···
Growth Rates 3
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 23258.2%-98.5%-1.0%75.9%57.2%·······
Revenue CAGR 3Y 50.5%-70.5%39.9%·········
Revenue CAGR 5Y 56.6%···········
Valuation (TTM) 14
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM $829M$4M$241M$243M$138M$88M$169M$16M$31M$158.3K$382.0K$175.0K
Net Income TTM $-2M$-599M$-205M$-176M$-141M$-85M$68M$-54M$-34M$-82M$-92M$-59M
Market Cap $4.68B·$2.88B$3.50B$6.51B$4.41B$2.69B$1.70B$324M$513M$343M$807M
Enterprise Value ·······$1.67B$299M$427M·$653M
P/E -3449.0-3.9-14.0-19.8-45.9-51.340.8-29.5-9.2···
P/S 5.6·12.014.447.150.115.9105.110.33237.7897.84613.0
P/B 10.0·10.68.815.99.511.017.74.05.43.14.8
P / Tangible Book 10.213.611.09.116.59.9······
P / Cash Flow 26.1·-18.7-25.738.0-46.215.6-35.9-13.5-8.0-5.2-22.8
P / FCF 29.8·-8.7-18.544.1-41.116.7-34.9-10.2-7.5-5.1-21.7
EV / EBITDA ·······-29.8-8.1-5.2·-12.6
EV / FCF ·······-34.3-9.4-6.3·-17.6
EV / Revenue ·······103.39.52699.8·3732.4
Earnings Yield -0.03%-25.8%-7.1%-5.1%-2.2%-1.9%2.5%-3.4%-10.8%···

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-09-302024-09-302023-09-302022-09-302021-09-30
Revenue $829M $4M $241M $243M $138M
Operating Margin % 11.9% · -85.2% -73.4% -107.8%
Net Income $-2M $-599M $-205M $-176M $-141M
Diluted EPS $-0.01 $-5.00 $-1.92 $-1.67 $-1.36

Institutional owners (13F) 536 filers · $10.7B total · As of Sept. 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 536
Value held $10.7B
New positions 124
Exited positions 54
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
124 (+4 vs prior Q) 54 (-2 vs prior Q) 161 (-7 vs prior Q) 162 (+41 vs prior Q) -134K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
BlackRock, Inc. $1,208,838,379 14,830,553 11.25% Shares
VANGUARD GROUP INC $1,015,310,304 15,293,121 9.45% Shares
Avoro Capital Advisors LLC $925,591,288 11,355,555 8.61% Shares
FMR LLC $655,324,429 8,039,804 6.10% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $517,698,946 6,351,355 4.82% Shares
VANGUARD CAPITAL MANAGEMENT LLC $498,103,779 6,110,953 4.63% Shares
STATE STREET CORP $464,170,106 5,694,640 4.32% Shares
NORGES BANK $317,606,649 3,896,536 2.95% Shares
Invesco Ltd. $316,582,884 3,883,976 2.95% Shares
GEODE CAPITAL MANAGEMENT, LLC $298,813,042 3,530,612 2.78% Shares
FRED ALGER MANAGEMENT, LLC $269,139,418 3,301,919 2.50% Shares
BAKER BROS. ADVISORS LP $162,431,742 1,992,783 1.51% Shares
Siren, L.L.C. $139,828,449 1,715,476 1.30% Shares
Vestal Point Capital, LP $128,378,250 1,575,000 1.19% Shares
DEERFIELD MANAGEMENT COMPANY, L.P. $113,221,873 1,389,055 1.05% Shares
FIRST TRUST ADVISORS LP $110,276,346 1,352,918 1.03% Shares
Driehaus Capital Management LLC $110,083,820 1,350,556 1.02% Shares
NORTHERN TRUST CORP $97,230,671 1,192,868 0.90% Shares
DIMENSIONAL FUND ADVISORS LP $96,310,585 1,181,608 0.90% Shares
GOLDMAN SACHS GROUP INC $93,737,071 1,150,007 0.87% Shares
BANK OF AMERICA CORP /DE/ $92,905,915 1,139,810 0.86% Shares
Hood River Capital Management LLC $91,352,088 1,120,747 0.85% Shares
Holocene Advisors, LP $90,164,487 1,106,177 0.84% Shares
JANUS HENDERSON GROUP PLC $90,119,095 1,436,990 0.84% Shares
MORGAN STANLEY $88,425,108 1,084,835 0.82% Shares
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $83,453,449 1,330,996 0.78% Shares
Fisher Asset Management, LLC $78,061,392 957,691 0.73% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $75,309,290 923,927 0.70% Shares
VANGUARD FIDUCIARY TRUST CO $73,093,114 896,738 0.68% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $70,718,076 867,600 0.66% Call option
UBS Group AG $70,222,495 861,520 0.65% Shares
Bank of New York Mellon Corp $70,060,927 859,538 0.65% Shares
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC $67,673,433 830,247 0.63% Shares
Western Financial Corp/CA $66,857,681 820,239 0.62% Shares
JPMORGAN CHASE & CO $51,770,437 637,399 0.48% Shares
Connor, Clark & Lunn Investment Management Ltd. $50,990,129 625,569 0.47% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $48,626,665 596,573 0.45% Shares
TWO SIGMA INVESTMENTS, LP $47,325,440 580,609 0.44% Shares
Pictet Asset Management Holding SA $46,708,118 573,419 0.43% Shares
BNP PARIBAS FINANCIAL MARKETS $45,534,991 558,643 0.42% Shares
1832 Asset Management L.P. $43,893,135 538,500 0.41% Shares
PRINCIPAL FINANCIAL GROUP INC $41,949,773 514,658 0.39% Shares
VOYA INVESTMENT MANAGEMENT LLC $39,409,678 483,495 0.37% Shares
Balyasny Asset Management L.P. $38,370,343 470,744 0.36% Shares
RENAISSANCE TECHNOLOGIES LLC $38,221,751 468,921 0.36% Shares
FRANKLIN RESOURCES INC $37,668,462 462,133 0.35% Shares
D. E. Shaw & Co., Inc. $35,176,456 431,560 0.33% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $34,600,995 424,500 0.32% Put option
Nuveen, LLC $33,898,624 415,883 0.32% Shares
RHUMBLINE ADVISERS $30,557,778 374,897 0.28% Shares

Show all 536 institutional owners →

Activists & 5%+ owners 3 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Sarepta Therapeutics, Inc., Sarepta Therapeutics Investments, Inc. ×2 filings Aug. 15, 2025 0.00% Amendment · SEC
Silence Therapeutics Plc ×3 filings Dec. 8, 2017 · Initial filing · SEC
Novartis Institutes for BioMedical Research, Inc., Novartis AG ×2 filings Nov. 28, 2017 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 33 insiders · 17 officers · 16 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Christopher Richard Anzalone Chief Executive Officer Jan. 2, 2026 S 3,792,739 0 25 $-24,010,562
Daniel Joseph Apel Chief Financial Officer April 22, 2026 S 162,905 0 3 $-934,286
Kenneth Allen Myszkowski Chief Financial Officer Jan. 7, 2025 S 455,433 0 0 $0
McDonnel Paul Clayton CFO (former) July 17, 2009 J · 0 0 $0
Joseph Theodore Kingsley III Chief Financial Officer March 29, 2007 A 12,000 0 0 $0
Leon Ekchian President Nov. 14, 2005 A · 0 0 $0
Patrick O'Brien COO Jan. 6, 2026 A 547,408 0 12 $-3,123,349
Bruce D Given Chief Operating Officer April 28, 2020 M 850,730 0 0 $0
James C Hamilton Chief Medical Officer April 23, 2026 S 226,958 0 10 $-4,626,561
Tracie Oliver Chief Commercial Officer July 2, 2024 S 127,107 0 0 $0
Javier San Martin Chief Medical Officer Jan. 5, 2024 S 198,497 0 0 $0
Curt Bradshaw Chief Scientific Officer Nov. 20, 2020 S 0 0 0 $0
Zhen Li Snr. VP, Chem and Non-Clin Dev Jan. 14, 2019 S 201,700 0 0 $0
Peter Brian Leone VP, Strategic Bus. Initiatives Oct. 19, 2018 M 130,000 0 0 $0
David L. Lewis Chief Scientific Officer Jan. 1, 2016 A 0 0 0 $0
STEWART R BRUCE Executive Chairman March 4, 2010 A 711,500 0 0 $0
James M Phillips JR Secretary March 31, 2004 A · 0 0 $0
Michael S Perry Director Aug. 18, 2026 S 111,459 0 2 $-2,004,418
Adeoye Y Olukotun Director Aug. 18, 2026 S 31,600 0 4 $-850,543
Matthew Gregory Cohen Director June 15, 2026 A 11,882 0 0 $0
Hongbo Lu Director May 12, 2026 S 52,012 0 1 $-228,334
Mauro Ferrari Director Dec. 26, 2025 S 69,053 0 2 $-1,020,512
Victoria Vakiener Director Dec. 19, 2025 S 35,723 0 3 $-679,491
William D. Waddill Director Dec. 19, 2025 S 56,563 0 3 $-566,039
Douglas S Ingram Director Dec. 16, 2025 A 46,215 0 0 $0
Douglas B Given Director Dec. 17, 2024 S 124,167 0 0 $0
Marianne De Backer Director Jan. 10, 2023 A 31,267 0 0 $0
Edward W Frykman Director Jan. 1, 2018 A 148,852 0 0 $0
Charles Mckenney Director March 4, 2015 A 42,220 0 0 $0
Leroy T Rahn Director March 4, 2010 A · 0 0 $0
David M Knott 10% owner March 21, 2007 S 742,600 0 0 $0
Marshall Robert Ching 10% owner June 23, 2005 U 28,666 0 0 $0
James Hassard · June 22, 2021 S 105,750 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

ETF ownership Held by 75 ETFs

20

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
ADPV · Series Portfolios Trust 4.99% 105,093 NS July 31, 2026 N-PORT
IBRN · iShares Trust 4.45% 4,021 SH Sept. 11, 2026 Daily
HTEC · EXCHANGE TRADED CONCEPTS TRUST 2.08% 16,973 NS July 31, 2026 N-PORT
RFG · Invesco Exchange-Traded Fund Trust 1.90% 98,200 SH Oct. 2, 2026 Daily
FXH · First Trust Exchange-Traded AlphaDE… 1.76% 217,383 NS July 31, 2026 N-PORT
XMMO · Invesco Exchange-Traded Fund Trust 1.64% 1,801,188 SH Oct. 2, 2026 Daily
BBP · ETFis Series Trust I 1.56% 18,212 NS July 31, 2026 N-PORT
PAMC · Pacer Funds Trust 1.03% 6,557 NS July 31, 2026 N-PORT
LABU · Direxion Shares ETF Trust 0.82% 47,707 NS July 31, 2026 N-PORT
IBB · iShares Trust 0.81% 1,011,317 SH Sept. 11, 2026 Daily
JSMD · Janus Detroit Street Trust 0.80% 99,071 NS July 31, 2026 N-PORT
FNY · First Trust Exchange-Traded AlphaDE… 0.66% 45,043 NS July 31, 2026 N-PORT
FDMO · FIDELITY COVINGTON TRUST 0.62% 66,366 NS July 31, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.61% 10,003 SH Oct. 2, 2026 Daily
IVOG · VANGUARD ADMIRAL FUNDS 0.60% 138,986 SH Aug. 19, 2026 Daily
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0.41% 33,395 NS July 31, 2026 N-PORT
IQSM · New York Life Investments ETF Trust 0.39% 15,107 NS July 31, 2026 N-PORT
PTMC · Pacer Funds Trust 0.34% 15,508 NS July 31, 2026 N-PORT
FNX · First Trust Exchange-Traded AlphaDE… 0.31% 50,547 NS July 31, 2026 N-PORT
IVOO · VANGUARD ADMIRAL FUNDS 0.31% 227,611 SH Aug. 19, 2026 Daily
VBK · VANGUARD INDEX FUNDS 0.30% 1,772,235 SH Aug. 19, 2026 Daily
QVMM · Invesco Exchange-Traded Fund Trust … 0.29% 18,702 SH Oct. 2, 2026 Daily
VFMO · VANGUARD WELLINGTON FUND 0.27% 67,223 SH Aug. 19, 2026 Daily
BKMC · BNY Mellon ETF Trust 0.26% 19,553 NS July 31, 2026 N-PORT
MIDU · Direxion Shares ETF Trust 0.26% 2,069 NS July 31, 2026 N-PORT
FSMD · FIDELITY COVINGTON TRUST 0.25% 72,735 NS July 31, 2026 N-PORT
PWS · Pacer Funds Trust 0.23% 652 NS July 31, 2026 N-PORT
ISCG · iShares Trust 0.21% 24,642 SH Sept. 11, 2026 Daily
JMOM · J.P. Morgan Exchange-Traded Fund Tr… 0.21% 61,794 NS July 31, 2026 N-PORT
IWP · iShares Trust 0.21% 478,561 SH Sept. 11, 2026 Daily
FAD · First Trust Exchange-Traded AlphaDE… 0.20% 13,526 NS July 31, 2026 N-PORT
IYH · iShares Trust 0.18% 78,886 SH Sept. 11, 2026 Daily
FTLS · First Trust Exchange-Traded Fund III 0.17% 49,621 NS July 31, 2026 N-PORT
SMMD · iShares Trust 0.16% 72,102 SH Sept. 11, 2026 Daily
ESML · iShares Trust 0.15% 51,818 SH Sept. 11, 2026 Daily
FHLC · FIDELITY COVINGTON TRUST 0.15% 56,561 NS July 31, 2026 N-PORT
VHT · VANGUARD WORLD FUND 0.14% 357,682 SH Aug. 19, 2026 Daily
VXF · VANGUARD INDEX FUNDS 0.13% 1,615,938 SH Aug. 19, 2026 Daily
VB · VANGUARD INDEX FUNDS 0.13% 3,068,726 SH Aug. 19, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.10% 41,974 SH Oct. 2, 2026 Daily
DFAS · Dimensional ETF Trust 0.10% 175,306 NS July 31, 2026 N-PORT
TILT · FlexShares Trust 0.09% 24,490 NS July 31, 2026 N-PORT
WSML · iShares Trust 0.09% 7,591 SH Sept. 11, 2026 Daily
IWR · iShares Trust 0.08% 552,714 SH Sept. 11, 2026 Daily
EQAL · Invesco Exchange-Traded Fund Trust … 0.07% 9,134 SH Oct. 2, 2026 Daily
LRND · New York Life Investments ETF Trust 0.07% 3,180 NS July 31, 2026 N-PORT
IWS · iShares Trust 0.04% 74,359 SH Sept. 11, 2026 Daily
SMDX · Tidal Trust III 0.04% 602 NS July 31, 2026 N-PORT
IUSG · iShares Trust 0.03% 123,000 SH Sept. 11, 2026 Daily
DFAC · Dimensional ETF Trust 0.03% 153,604 NS July 31, 2026 N-PORT
RWK · Invesco Exchange-Traded Fund Trust … 0.02% 4,240 SH Oct. 2, 2026 Daily
IWF · iShares Trust 0.02% 319,335 SH Sept. 11, 2026 Daily
VONE · VANGUARD SCOTTSDALE FUNDS 0.02% 22,223 SH Aug. 19, 2026 Daily
VONG · VANGUARD SCOTTSDALE FUNDS 0.02% 133,946 SH Aug. 19, 2026 Daily
VTHR · VANGUARD SCOTTSDALE FUNDS 0.02% 11,327 SH Aug. 19, 2026 Daily
ESGV · VANGUARD WORLD FUND 0.02% 30,534 SH Aug. 19, 2026 Daily
DFAU · Dimensional ETF Trust 0.02% 25,782 NS July 31, 2026 N-PORT
RECS · Columbia ETF Trust I 0.02% 11,168 NS July 31, 2026 N-PORT
ITOT · iShares Trust 0.02% 185,916 SH Sept. 11, 2026 Daily
IWB · iShares Trust 0.02% 93,225 SH Sept. 11, 2026 Daily
IWV · iShares Trust 0.01% 36,139 SH Sept. 11, 2026 Daily
DCOR · Dimensional ETF Trust 0.01% 5,886 NS July 31, 2026 N-PORT
DFSU · Dimensional ETF Trust 0.01% 3,408 NS July 31, 2026 N-PORT
IWD · iShares Trust 0.01% 111,121 SH Sept. 11, 2026 Daily
REVS · Columbia ETF Trust I 0.01% 439 NS July 31, 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0.01% 4,247,432 SH Aug. 19, 2026 Daily
VT · VANGUARD INTERNATIONAL EQUITY INDEX… 0.01% 111,719 SH Aug. 19, 2026 Daily
VONV · VANGUARD SCOTTSDALE FUNDS 0.01% 30,273 SH Aug. 19, 2026 Daily
DFUS · Dimensional ETF Trust 0.01% 24,661 NS July 31, 2026 N-PORT
IJH · iShares Trust · 4,942,845 SH Sept. 11, 2026 Daily
IJK · iShares Trust · 816,879 SH Sept. 11, 2026 Daily
XJH · iShares Trust · 19,242 SH Sept. 8, 2026 Daily
ISCB · iShares Trust · 5,539 SH Sept. 11, 2026 Daily
ISCV · iShares Trust · 10,026 SH Sept. 11, 2026 Daily
SMLF · iShares Trust · 45,534 SH Sept. 11, 2026 Daily

ARWR Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 20 analysts BUY
Median target $104.00 +62.0%
6 30.0% Strong Buy
13 65.0% Buy
1 5.0% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

13 analysts · 2026-09-28

Mean target $107.23 +67.1%

← Below all targets Current price $64.19
Low$74.00 Mean$107.23 High$126.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
ARWR $4.68B -3449.0 23258.2% -0.20% -0.50% ·
KRYS $7.20B 36.0 33.9% 52.6% 18.1% ·
KYMR $6.33B -21.1 -16.7% -794.0% -24.4% ·
CYTK $7.81B -9.7 376.6% -891.6% 152.7% ·
PTGX $5.47B -42.6 -89.4% -282.8% -20.3% ·
PCVX $6.05B -8.2 · · -26.6% ·
TGTX $4.63B 10.8 87.3% 72.6% 96.7% ·
CAI $7.62B -8.4 97.0% -8.4% -13.2% ·

Latest News Recent headlines mentioning this company

23
Arrowhead Pharmaceuticals Inc. (ARWR): Billionaire Ken Fisher Bets Big on Pharma Yahoo Finance · 6 months, 2 weeks ago

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

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Source: SEC 10-Q filed Aug 4, 2026