Fred A Middleton
First SEC filing: Feb. 2, 2011 · Latest: Feb. 2, 2011
Insider at
Insider transactions
Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted
| Date | Ticker | Code | Shares | Price | Value | Owned after | Δ own | A/D | vs now |
|---|---|---|---|---|---|---|---|---|---|
| June 25, 2026 | CALC | P | 248,972 | $0.80 | $199,178 | 1,063,272 Indirect | +30.57% | Acquired | -60.0% (price as of 2026-10-02) |
| June 24, 2025 | CALC | A | 10,000 | · | · | 10,000 Direct | · | Acquired | (price as of 2026-10-02) |
| June 24, 2025 | CALC | A | 6,562 | · | · | 6,562 Direct | · | Acquired | (price as of 2026-10-02) |
| June 24, 2025 | CALC | A | 19,687 | · | · | 19,687 Direct | · | Acquired | (price as of 2026-10-02) |
| June 24, 2025 | CALC | A | 10,000 | · | · | 10,000 Direct | · | Acquired | (price as of 2026-10-02) |
| Dec. 6, 2024 | CALC | P | 4,800 | $2.65 | $12,720 | 36,514 Direct | +15.14% | Acquired | -87.9% (price as of 2026-10-02) |
| Nov. 1, 2024 | CALC | P | 20,000 | $3.75 | $75,000 | 31,714 Direct | +170.74% | Acquired | -91.5% (price as of 2026-10-02) |
| Nov. 1, 2024 | CALC | P | 86,867 | $3.75 | $325,751 | 814,300 Indirect | +11.94% | Acquired | -91.5% (price as of 2026-10-02) |
| Nov. 1, 2024 | CALC | P | 877 | $3.75 | $3,289 | 22,479 Indirect | +4.06% | Acquired | -91.5% (price as of 2026-10-02) |
| Aug. 27, 2024 | CALC | A | 10,000 | · | · | 10,000 Direct | · | Acquired | (price as of 2026-10-02) |
| March 28, 2024 | CALC | A | 10,000 | · | · | 10,000 Direct | · | Acquired | (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 243,356 | $3.70 | $900,417 | 946,744 Indirect | +34.60% | Acquired | -91.4% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 144,676 | $3.70 | $535,301 | 727,433 Indirect | +24.83% | Acquired | -91.4% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 194,472 | $3.70 | $719,546 | 435,148 Indirect | +80.80% | Acquired | -91.4% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 51,032 | $3.70 | $188,818 | 114,260 Indirect | +80.71% | Acquired | -91.4% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 13,184 | $3.70 | $48,781 | 27,609 Indirect | +91.40% | Acquired | -91.4% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 3,920 | $3.70 | $14,504 | 21,602 Indirect | +22.17% | Acquired | -91.4% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 28,744 | $3.70 | $106,353 | 30,292 Indirect | +1856.85% | Acquired | -91.4% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 121,678 | $0.12 | $14,601 | 121,678 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 121,678 | $0.12 | $14,601 | 121,678 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 72,338 | $0.12 | $8,681 | 72,338 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 72,338 | $0.12 | $8,681 | 72,338 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 97,236 | $0.12 | $11,668 | 97,236 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 97,236 | $0.12 | $11,668 | 97,236 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 25,516 | $0.12 | $3,062 | 25,516 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 25,516 | $0.12 | $3,062 | 25,516 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 6,592 | $0.12 | $791 | 6,592 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 6,592 | $0.12 | $791 | 6,592 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 1,960 | $0.12 | $235 | 1,960 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 1,960 | $0.12 | $235 | 1,960 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 14,372 | $0.12 | $1,725 | 14,372 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| Jan. 23, 2024 | CALC | P | 14,372 | $0.12 | $1,725 | 14,372 Indirect | · | Acquired | 166.7% (price as of 2026-10-02) |
| June 9, 2023 | CALC | P | 714 | $5.20 | $3,713 | 11,714 Direct | +6.49% | Acquired | -93.8% (price as of 2026-10-02) |
| June 7, 2023 | CALC | P | 500 | $5.20 | $2,600 | 11,000 Direct | +4.76% | Acquired | -93.8% (price as of 2026-10-02) |
| June 6, 2023 | CALC | P | 500 | $4.88 | $2,440 | 10,500 Direct | +5.00% | Acquired | -93.4% (price as of 2026-10-02) |
| May 19, 2023 | CALC | P | 10,000 | $2.85 | $28,500 | 10,000 Direct | · | Acquired | -88.8% (price as of 2026-10-02) |
| May 8, 2023 | CALC | A | 20,000 | · | · | 20,000 Direct | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 8,176 | · | · | 8,176 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 167 | · | · | 167 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 113 | · | · | 113 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 840 | · | · | 840 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 569 | · | · | 569 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 3,249 | · | · | 3,249 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 2,203 | · | · | 2,203 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 12,380 | · | · | 12,380 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 8,393 | · | · | 8,393 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 183 | · | · | 183 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 237 | · | · | 237 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 15,403 | · | · | 15,403 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 6,852 | · | · | 6,852 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 1,910 | · | · | 1,910 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 2,685 | · | · | 2,685 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 16,539 | · | · | 16,539 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 2,672 | · | · | 2,672 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 5,760 | · | · | 5,760 Direct | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 1,548 | · | · | 1,548 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 47,052 | · | · | 47,052 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 14,425 | · | · | 14,425 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 256,852 | · | · | 256,852 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 8,884 | · | · | 8,884 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 7,456 | · | · | 7,456 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 17,682 | · | · | 17,682 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 582,757 | · | · | 582,757 Indirect | · | Acquired | (price as of 2026-10-02) |
| March 20, 2023 | CALC | A | 703,388 | · | · | 703,388 Indirect | · | Acquired | (price as of 2026-10-02) |
| June 24, 2013 | PCRX | S 10b5-1 | 5,900 | $28.70 | $169,330 | 0 Indirect | -100.00% | Disposed | -12.2% (price as of 2026-10-02) |
| June 21, 2013 | PCRX | S 10b5-1 | 2,828 | $28.49 | $80,570 | 5,900 Indirect | -32.40% | Disposed | -11.5% (price as of 2026-10-02) |
| June 21, 2013 | PCRX | S 10b5-1 | 36,374 | $29.22 | $1,062,848 | 8,728 Indirect | -80.65% | Disposed | -13.7% (price as of 2026-10-02) |
| June 21, 2013 | PCRX | S 10b5-1 | 2,222 | $28.49 | $63,305 | 0 Indirect | -100.00% | Disposed | -11.5% (price as of 2026-10-02) |
| June 21, 2013 | PCRX | S 10b5-1 | 28,576 | $29.22 | $834,991 | 2,222 Indirect | -92.79% | Disposed | -13.7% (price as of 2026-10-02) |
| June 20, 2013 | PCRX | S 10b5-1 | 66,100 | $28.93 | $1,912,273 | 30,798 Indirect | -68.22% | Disposed | -12.9% (price as of 2026-10-02) |
| June 19, 2013 | PCRX | S 10b5-1 | 48,400 | $29.76 | $1,440,384 | 96,898 Indirect | -33.31% | Disposed | -15.3% (price as of 2026-10-02) |
| June 18, 2013 | PCRX | S 10b5-1 | 29,600 | $29.48 | $872,608 | 145,298 Indirect | -16.92% | Disposed | -14.5% (price as of 2026-10-02) |
| June 12, 2013 | PCRX | A | 7,000 | · | · | 7,000 Direct | · | Acquired | (price as of 2026-10-02) |
| June 5, 2013 | PCRX | J | 7,433 | · | · | 70,399 Direct | +11.80% | Acquired | (price as of 2026-10-02) |
| June 5, 2013 | PCRX | J | 241,185 | · | · | 174,898 Indirect | -57.97% | Disposed | (price as of 2026-10-02) |
| June 5, 2013 | PCRX | J | 316,660 | · | · | 45,102 Indirect | -87.53% | Disposed | (price as of 2026-10-02) |
| June 5, 2012 | PCRX | A | 7,000 | · | · | 7,000 Direct | · | Acquired | (price as of 2026-10-02) |
| March 25, 2012 | PCRX | G | 5,000 | · | · | 62,966 Direct | -7.36% | Disposed | (price as of 2026-10-02) |
| Nov. 21, 2011 | PCRX | P | 10,000 | $6.50 | $65,000 | 10,000 Direct | · | Acquired | 287.8% (price as of 2026-10-02) |
| June 2, 2011 | PCRX | A | 15,692 | · | · | 15,692 Direct | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 736,583 | · | · | 736,583 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 14,877 | · | · | 14,877 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 24,871 | · | · | 24,871 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 29,634 | · | · | 29,634 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 681,715 | · | · | 681,715 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 344,355 | · | · | 344,355 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 12,058 | · | · | 12,058 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 14,366 | · | · | 14,366 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 341,788 | · | · | 341,788 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 129,445 | · | · | 129,445 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 4,533 | · | · | 4,533 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 5,400 | · | · | 5,400 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 128,479 | · | · | 128,479 Indirect | · | Acquired | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | P | 46,379 | $7.00 | $324,653 | 46,379 Indirect | · | Acquired | 260.1% (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | P | 27,931 | $7.00 | $195,517 | 27,931 Indirect | · | Acquired | 260.1% (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | P | 4,297 | $7.00 | $30,079 | 4,297 Indirect | · | Acquired | 260.1% (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | P | 5,119 | $7.00 | $35,833 | 5,119 Indirect | · | Acquired | 260.1% (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | P | 184,131 | $7.00 | $1,288,917 | 184,131 Indirect | · | Acquired | 260.1% (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 736,583 | · | · | 0 Indirect | -100.00% | Disposed | (price as of 2026-10-02) |
| Feb. 8, 2011 | PCRX | C | 14,877 | · | · | 0 Indirect | -100.00% | Disposed | (price as of 2026-10-02) |
Showing latest 100 of 111 transactions
P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding
Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.
Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.
| Date | Ticker | Security | Underlying | Exercise price | Expiration | Shares | A/D |
|---|---|---|---|---|---|---|---|
| June 24, 2025 | CALC | Director Stock Option (Right to Buy) | Common Stock | $1.53 | April 22, 2035 | 10,000 | Acquired |
| June 24, 2025 | CALC | Director Stock Option (Right to Buy) | Common Stock | $1.53 | April 22, 2035 | 6,562 | Acquired |
| June 24, 2025 | CALC | Director Stock Option (Right to Buy) | Common Stock | $1.53 | April 22, 2035 | 19,687 | Acquired |
| June 24, 2025 | CALC | Director Stock Option (Right to Buy) | Common Stock | $1.65 | June 23, 2035 | 10,000 | Acquired |
| Aug. 27, 2024 | CALC | Director Stock Option (Right to Buy) | Common Stock | $4.16 | Aug. 26, 2034 | 10,000 | Acquired |
| March 28, 2024 | CALC | Director Stock Option (Right to Buy) | Common Stock | $4.16 | March 27, 2034 | 10,000 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $5.36 | Dec. 31, 2024 | 121,678 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $7.15 | Dec. 31, 2026 | 121,678 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $5.36 | Dec. 31, 2024 | 72,338 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $7.15 | Dec. 31, 2026 | 72,338 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $5.36 | Dec. 31, 2024 | 97,236 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $7.15 | Dec. 31, 2026 | 97,236 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $5.36 | Dec. 31, 2024 | 25,516 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $7.15 | Dec. 31, 2026 | 25,516 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $5.36 | Dec. 31, 2024 | 6,592 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $7.15 | Dec. 31, 2026 | 6,592 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $5.36 | Dec. 31, 2024 | 1,960 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $7.15 | Dec. 31, 2026 | 1,960 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $5.36 | Dec. 31, 2024 | 14,372 | Acquired |
| Jan. 23, 2024 | CALC | Warrant | Common Stock | $7.15 | Dec. 31, 2026 | 14,372 | Acquired |
| May 8, 2023 | CALC | Director Stock Option (Right to Buy) | Common Stock | $3.25 | May 7, 2033 | 20,000 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | June 25, 2026 | 167 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | March 4, 2026 | 113 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | June 25, 2026 | 840 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | March 4, 2026 | 569 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | June 25, 2026 | 3,249 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | March 4, 2026 | 2,203 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | June 25, 2026 | 12,380 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | Feb. 22, 2026 | 8,393 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | June 25, 2026 | 183 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | March 4, 2026 | 237 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | June 25, 2026 | 15,403 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | Feb. 22, 2026 | 6,852 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $26.74 | Feb. 28, 2027 | 1,910 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | June 25, 2026 | 2,685 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $27.94 | Feb. 22, 2026 | 16,539 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $26.74 | Feb. 28, 2027 | 2,672 | Acquired |
| March 20, 2023 | CALC | Warrant | Common Stock | $10.42 | Oct. 24, 2032 | 5,760 | Acquired |
| June 12, 2013 | PCRX | Stock Option (Right to Buy) | Common Stock | $29.20 | June 11, 2023 | 7,000 | Acquired |
| June 5, 2012 | PCRX | Common Stock | Common Stock | $10.81 | June 4, 2022 | 7,000 | Acquired |
| June 2, 2011 | PCRX | Stock option (right to buy) | Common Stock | $13.98 | June 2, 2021 | 15,692 | Acquired |
| Feb. 8, 2011 | PCRX | Series A Convertible Preferred Stock | Common Stock | · | · | 736,583 | Disposed |
| Feb. 8, 2011 | PCRX | Series A Convertible Preferred Stock | Common Stock | · | · | 14,877 | Disposed |
| Feb. 8, 2011 | PCRX | Series A Convertible Preferred Stock | Common Stock | · | · | 24,871 | Disposed |
| Feb. 8, 2011 | PCRX | Series A Convertible Preferred Stock | Common Stock | · | · | 29,634 | Disposed |
| Feb. 8, 2011 | PCRX | Series A Convertible Preferred Stock | Common Stock | · | · | 681,715 | Disposed |
| Feb. 8, 2011 | PCRX | Convertible Promissory Notes | Common Stock | · | · | 344,355 | Disposed |
| Feb. 8, 2011 | PCRX | Convertible Promissory Notes | Common Stock | · | · | 12,058 | Disposed |
| Feb. 8, 2011 | PCRX | Convertible Promissory Notes | Common Stock | · | · | 14,366 | Disposed |
| Feb. 8, 2011 | PCRX | Convertible Promissory Notes | Common Stock | · | · | 341,788 | Disposed |
| Feb. 8, 2011 | PCRX | Convertible Promissory Notes | Common Stock | · | · | 129,445 | Disposed |
| Feb. 8, 2011 | PCRX | Convertible Promissory Notes | Common Stock | · | · | 4,533 | Disposed |
| Feb. 8, 2011 | PCRX | Convertible Promissory Notes | Common Stock | · | · | 5,400 | Disposed |
| Feb. 8, 2011 | PCRX | Convertible Promissory Notes | Common Stock | · | · | 128,479 | Disposed |
Exercise/conversion price is blank when not applicable (e.g. RSUs).
Initial ownership (Form 3) 27 holdings
Securities held when first becoming an insider, per SEC Form 3.
| Date | Ticker | Security | Shares | Ownership |
|---|---|---|---|---|
| Feb. 2, 2011 | PCRX | Common Stock | 125,800 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock | 55,788 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock | 1,995 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock | 2,377 | Indirect |
| Feb. 2, 2011 | PCRX | Series A Convertible Preferred Stock | 736,583 | Indirect |
| Feb. 2, 2011 | PCRX | Series A Convertible Preferred Stock | 14,877 | Indirect |
| Feb. 2, 2011 | PCRX | Series A Convertible Preferred Stock | 24,871 | Indirect |
| Feb. 2, 2011 | PCRX | Series A Convertible Preferred Stock | 29,634 | Indirect |
| Feb. 2, 2011 | PCRX | Series A Convertible Preferred Stock | 681,715 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock Warrant (Right to Buy) | 17,973 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock Warrant (Right to Buy) | 629 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock Warrant (Right to Buy) | 749 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock Warrant (Right to Buy) | 17,839 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock Warrant (Right to Buy) | 20,220 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock Warrant (Right to Buy) | 708 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock Warrant (Right to Buy) | 843 | Indirect |
| Feb. 2, 2011 | PCRX | Common Stock Warrant (Right to Buy) | 20,069 | Indirect |
| Feb. 2, 2011 | PCRX | Convertible Promissory Notes | 344,355 | Indirect |
| Feb. 2, 2011 | PCRX | Convertible Promissory Notes | 12,058 | Indirect |
| Feb. 2, 2011 | PCRX | Convertible Promissory Notes | 14,366 | Indirect |
| Feb. 2, 2011 | PCRX | Convertible Promissory Notes | 341,788 | Indirect |
| Feb. 2, 2011 | PCRX | Convertible Promissory Notes | 129,445 | Indirect |
| Feb. 2, 2011 | PCRX | Convertible Promissory Notes | 5,400 | Indirect |
| Feb. 2, 2011 | PCRX | Convertible Promissory Notes | 128,479 | Indirect |
| Feb. 2, 2011 | PCRX | Convertible Promissory Notes | 4,533 | Indirect |
| Feb. 2, 2011 | PCRX | Stock Option (Right to Buy) | 4,649 | Direct |
| Feb. 2, 2011 | PCRX | Stock Option (Right to Buy) | 1,394 | Direct |