CALC CalciMedica, Inc. - Common Stock
$0.63
Price · Aug 19, 2026
Fundamentals as of Aug 11, 2026
52W Range
$0–$7
3% of range
Analyst Rating
BUY
9 analysts
Price Target
$10
+1567% upside
P/E (TTM)
-3.3
ROE
—
Net Profit Margin
—
CALC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range
Price
$0.63
Market Cap
—
P/E (TTM)
-3.3
EPS (TTM)
$-1.97
Revenue (TTM)
—
Div Yield
—
ROE
—
Debt/Equity
—
52W Range
$0 – $7
CALC Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view
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10-Year Performance Revenue, net income, margins and EPS trends
Revenue & Net Income
—
EPS
$-1.97
2021-12-31
→
2025-12-31
Free Cash Flow
—
2020-12-31
→
2024-12-31
Margins
—
Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?
Metric
5Y trend
CALC
Peer Median
P/E (TTM)
-3.3
53.4
Profitability Gross, operating and net margins; ROE, ROA, ROIC
Metric
5Y trend
CALC
Peer Median
Financial Health Debt, liquidity, solvency — balance sheet strength
Metric
5Y trend
CALC
Peer Median
Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR
Metric
5Y trend
CALC
Peer Median
Revenue YoY
-29.7%
—
Capital Efficiency Asset turnover, inventory turnover, receivables turnover
Metric
5Y trend
CALC
Peer Median
CALC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside
BUY
9 analysts
- Strong Buy 2 22.2%
- Buy 5 55.6%
- Hold 2 22.2%
- Sell 0 0.0%
- Strong Sell 0 0.0%
12-Month Price Target
2 analysts · 2026-08-19
Median
$10.50
← Below all targets
$0.63
Low
$6.00
High
$15.00
Median target
$10.50
+1566.7%
Mean target
$10.50
+1566.7%
Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date
Avg Surprise
0.01%
| Period | EPS Actual | EPS Est | Surprise |
|---|---|---|---|
| March 31, 2026 | $0.30 | $-0.29 | 0.59% |
| Dec. 31, 2025 | $-0.73 | $-0.42 | -0.31% |
| Sept. 30, 2025 | $-0.52 | $-0.42 | -0.10% |
| June 30, 2025 | $-0.40 | $-0.36 | -0.04% |
| March 31, 2025 | $-0.36 | $-0.31 | -0.05% |
| Dec. 31, 2024 | $-0.38 | $-0.36 | -0.02% |
Peer comparison (GICS sub-industry) Key metrics vs sector peers
| Ticker | Market Cap | P/E | Rev YoY | Net Margin | ROE | Gross Margin |
|---|---|---|---|---|---|---|
| CALC | — | -3.3 | -29.7% | — | — | — |
| QCLS | — | -0.5 | — | — | — | — |
| CTXR | — | -0.4 | — | — | — | — |
| RKTO | — | — | — | — | — | — |
| TVRD | $40M | -1.3 | -66.0% | — | -67.6% | — |
| LPCN | $49M | -4.8 | -82.3% | -487.1% | -60.9% | — |
| LLY | — | 46.8 | 44.7% | 31.7% | 101.2% | — |
Full Fundamentals All metrics by year — income statement, balance sheet, cash flow
Income Statement 14
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $15M | $14M | $16M | $8M | $19M | $21M | $31M | |
| SG&A Expense | $8M | $10M | $22M | $6M | $17M | $9M | $7M | |
| Operating Expenses | $23M | $24M | $38M | $14M | $36M | $30M | $38M | |
| Operating Income | $-23M | $-24M | $-38M | $-14M | $-36M | $-30M | $-38M | |
| Interest Income | · | · | · | $575.0K | $126.0K | $143.0K | $393.0K | |
| Other Non-op | $268.0K | $0 | $550.0K | $-28.0K | · | · | · | |
| Pretax Income | $-30M | $-14M | · | · | · | · | · | |
| Income Tax | $0 | $0 | $1.0K | $1.0K | · | · | · | |
| Net Income | $-30M | $-14M | $-34M | $-8M | $-36M | $-28M | $-37M | |
| EPS (Basic) | $-1.97 | $-1.22 | $-7.66 | $-111.16 | $-1.69 | · | · | |
| EPS (Diluted) | $-1.97 | $-1.22 | $-7.66 | $-111.16 | $-1.69 | · | · | |
| Shares (Basic) | 15,011,321 | 11,245,915 | 4,486,258 | 82,245 | 21,199,291 | · | · | |
| Shares (Diluted) | 15,011,321 | 11,245,915 | 4,486,258 | 82,245 | 21,199,291 | · | · | |
| EBITDA | · | $-24M | · | · | $-36M | $-30M | · |
Balance Sheet 19
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $12M | $8M | $6M | $1M | $13M | $33M | $16M | |
| Short-term Investments | $1M | $11M | $6M | $0 | $50M | $62M | $20M | |
| Prepaid Expense | $259.0K | $248.0K | $296.0K | $254.0K | $3M | $4M | $315.0K | |
| Other Current Assets | · | · | · | · | $1M | $1M | · | |
| Current Assets | $14M | $20M | $12M | $2M | $67M | $99M | $36M | |
| PP&E (Net) | $50.0K | $119.0K | $167.0K | $147.0K | $2M | $2M | $2M | |
| PP&E (Gross) | · | · | · | · | $4M | $3M | $3M | |
| Accum. Depreciation | · | · | · | · | $2M | $1M | $739.0K | |
| Total Assets | $14M | $20M | $12M | $3M | $69M | $102M | $41M | |
| Accounts Payable | $1M | $2M | $1M | $3M | $527.0K | $3M | $5M | |
| Accrued Liabilities | · | · | · | $200.0K | $304.0K | $1M | $2M | |
| Current Liabilities | $4M | $4M | $4M | $5M | $4M | $7M | $12M | |
| Total Liabilities | $20M | $5M | $4M | $13M | $4M | $7M | $12M | |
| Common Stock | $4.0K | $4.0K | $1.0K | $1.0K | $2.0K | $2.0K | · | |
| Retained Earnings | $-189M | $-160M | $-146M | $-112M | $-169M | $-133M | $-106M | |
| AOCI | $0 | $4.0K | $2.0K | $-37.0K | $-16.0K | $-4.0K | $3.0K | |
| Stockholders' Equity | $-7M | $14M | $8M | $-71M | $-64M | $95M | $-103M | |
| Liabilities + Equity | $14M | $20M | $12M | $3M | $69M | $102M | $41M | |
| Shares Outstanding | 15,437,410 | 13,481,917 | 5,754,505 | 84,165 | 21,357,773 | 20,979,265 | 1,371,467 |
Cash Flow 12
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | · | · | $58.0K | $52.0K | · | · | · | |
| Stock-based Comp | $3M | $2M | $12M | $2M | $5M | $2M | $738.0K | |
| Restructuring | · | · | · | $3M | · | · | · | |
| Operating Cash Flow | $-21M | $-21M | $-26M | $-12M | $-32M | $-32M | $-31M | |
| CapEx | $28.0K | $8.0K | $78.0K | $4.0K | $488.0K | $1M | $605.0K | |
| Investing Cash Flow | $10M | $-4M | $9M | $-4.0K | $11M | $-43M | $-21M | |
| Stock Issued | $8.0K | $28M | $10M | · | · | $96M | · | |
| Net Stock Activity | · | $28M | · | · | · | $96M | · | |
| Financing Cash Flow | $15M | $28M | $21M | $8M | $695.0K | $92M | $55M | |
| Net Change in Cash | $4M | $2M | $4M | $-3M | $-20M | $18M | $3M | |
| Taxes Paid | $0 | · | · | · | · | · | · | |
| Free Cash Flow | · | $-21M | · | · | $-32M | $-33M | · |
Profitability 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | · | -85.7% | · | · | -41.9% | -38.6% | · | |
| ROE | · | -116.9% | · | · | -52.2% | -29.7% | · |
Liquidity & Solvency 2
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | · | 5.3 | · | · | 16.5 | 14.2 | · | |
| Quick Ratio | · | 5.1 | · | · | 15.7 | 13.6 | · |
Growth Rates 1
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -29.7% | · | · | · | · | · | · |
Valuation (TTM) 10
| Metric | Trend | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $713.0K | $1M | · | · | · | · | · | |
| Net Income TTM | $-30M | $-14M | $-34M | $-8M | $-36M | $-28M | · | |
| Market Cap | · | $48M | · | · | · | · | · | |
| P/E | -3.3 | -2.9 | -0.4 | · | · | · | · | |
| P/S | · | 47.1 | · | · | · | · | · | |
| P/B | · | 3.3 | · | · | · | · | · | |
| P / Tangible Book | · | 3.3 | 2.0 | · | · | · | · | |
| P / Cash Flow | · | -2.3 | · | · | · | · | · | |
| P / FCF | · | -2.3 | · | · | · | · | · | |
| Earnings Yield | -29.9% | -34.5% | -267.8% | · | · | · | · |
Income Statement 13
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $2M | $3M | $3M | $4M | $4M | $4M | $4M | $4M | $4M | $3M | $3M | $4M | $6M | $2M | $1M | $2M | |
| SG&A Expense | $2M | $2M | $1M | $2M | $3M | $2M | $2M | $2M | $2M | $3M | $2M | $3M | $16M | $1M | $2M | $1M | |
| Operating Expenses | $4M | $6M | $4M | $6M | $7M | $6M | $6M | $6M | $7M | $6M | $5M | $7M | $22M | $3M | $3M | $4M | |
| Operating Income | $-4M | $-6M | $-4M | $-6M | $-7M | $-6M | $-6M | $-6M | $-7M | $-6M | $-5M | $-7M | $-22M | $-3M | $-3M | $-4M | |
| Interest Income | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $171.0K | $60.0K | |
| Other Non-op | $231.0K | $11M | $-1M | $0 | $269.0K | $1M | $-6M | $0 | $0 | $6M | $214.0K | $279.0K | $-116.0K | $50.0K | $-49.0K | $-29.0K | |
| Income Tax | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $1.0K | $0 | $0 | |
| Net Income | $-8M | $5M | $-11M | $-8M | $-6M | $-5M | $-4M | $-6M | $-4M | $130.0K | $-5M | $-6M | $-19M | $1M | $-3M | $-3M | |
| EPS (Basic) | $-0.45 | $0.31 | $-0.69 | $-0.52 | $-0.40 | $-0.36 | $-0.37 | $-0.50 | $-0.36 | $0.01 | $-0.82 | $-1.11 | $-23.43 | $2.56 | $-31.04 | $-36.55 | |
| EPS (Diluted) | $-0.45 | $0.30 | $-0.69 | $-0.52 | $-0.40 | $-0.36 | $-0.37 | $-0.50 | $-0.36 | $0.01 | $-0.82 | $-1.11 | $-23.43 | $2.56 | $-31.04 | $-36.55 | |
| Shares (Basic) | 17,100,457 | 15,822,163 | -29,182,108 | 15,076,456 | 14,995,404 | 14,121,569 | -20,772,619 | 11,134,964 | 11,129,053 | 9,754,517 | 5,667,343 | 5,661,933 | 823,069 | -162,510 | 83,154 | 82,923 | |
| Shares (Diluted) | 17,100,457 | 16,328,947 | -29,182,108 | 15,076,456 | 14,995,404 | 14,121,569 | -21,065,517 | 11,134,964 | 11,129,053 | 10,047,415 | 5,667,343 | 5,661,933 | 823,069 | -162,510 | 83,154 | 82,923 | |
| EBITDA | $-4M | $-6M | · | $-6M | $-7M | $-6M | · | $-6M | $-7M | $-6M | $-5M | $-7M | $-22M | · | $-10M | $-8M |
Balance Sheet 16
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $19M | $8M | $12M | $5M | $6M | $13M | $8M | $9M | $5M | $7M | $12M | $19M | $24M | $1M | $10M | $14M | |
| Short-term Investments | $0 | $0 | $1M | $9M | $12M | $12M | $11M | $5M | $14M | $19M | $3M | · | $10M | $0 | $33M | $37M | |
| Prepaid Expense | $575.0K | $122.0K | $259.0K | $539.0K | $655.0K | $197.0K | $248.0K | $1M | $1M | $894.0K | $682.0K | $961.0K | $336.0K | $254.0K | $1M | $1M | |
| Current Assets | $19M | $9M | $14M | $15M | $19M | $25M | $20M | $16M | $20M | $27M | $15M | $20M | $34M | $2M | $45M | $52M | |
| PP&E (Net) | $36.0K | $43.0K | $50.0K | $49.0K | $105.0K | $118.0K | $119.0K | $130.0K | $138.0K | $153.0K | $187.0K | $199.0K | $134.0K | $147.0K | · | $2M | |
| Total Assets | $20M | $9M | $14M | $15M | $19M | $25M | $20M | $16M | $21M | $27M | $16M | $20M | $35M | $3M | $45M | $54M | |
| Accounts Payable | $2M | $2M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $2M | $2M | $3M | $498.0K | $1M | |
| Accrued Liabilities | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $200.0K | $463.0K | |
| Current Liabilities | $3M | $5M | $4M | $4M | $3M | $4M | $4M | $4M | $4M | $4M | $4M | $4M | $13M | $5M | $4M | $4M | |
| Total Liabilities | $14M | $10M | $20M | $15M | $13M | $14M | $5M | $7M | $7M | $10M | $4M | $4M | $13M | $13M | $4M | $4M | |
| Common Stock | $6.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $3.0K | $3.0K | $3.0K | $1.0K | $1.0K | $1.0K | $1.0K | $2.0K | $2.0K | |
| Retained Earnings | $-192M | $-184M | $-189M | $-179M | $-171M | $-165M | $-160M | $-156M | $-150M | $-146M | $-142M | $-137M | $-131M | $-112M | $-197M | $-188M | |
| AOCI | $-1.0K | · | $0 | $1.0K | $-4.0K | $-1.0K | $4.0K | $4.0K | $-9.0K | $-17.0K | · | · | · | · | $-123.0K | $-179.0K | |
| Stockholders' Equity | $6M | $-1M | $-7M | $-268.0K | $6M | $11M | $14M | $9M | $14M | $17M | $12M | $16M | $22M | $-71M | $42M | $50M | |
| Liabilities + Equity | $20M | $9M | $14M | $15M | $19M | $25M | $20M | $16M | $21M | $27M | $16M | $20M | $35M | $3M | $45M | $54M | |
| Shares Outstanding | 30,736,401 | 15,746,416 | 15,437,410 | 14,257,234 | 13,971,990 | 13,971,990 | 13,481,917 | 10,761,917 | 10,750,156 | 10,740,115 | 5,684,873 | 5,661,933 | 5,661,933 | 84,165 | · | · |
Cash Flow 12
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | · | · | · | · | · | · | $12.0K | $14.0K | $13.0K | $13.0K | $13.0K | $13.0K | |
| Stock-based Comp | $540.0K | $561.0K | $622.0K | $625.0K | $1M | $549.0K | $632.0K | $781.0K | $486.0K | $414.0K | $482.0K | $463.0K | $11M | $752.0K | $-2M | $-886.0K | |
| Restructuring | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $2M | · | |
| Other Non-cash | · | · | · | · | · | · | · | · | · | · | · | · | $3M | · | · | · | |
| Operating Cash Flow | $-5M | $-5M | $-5M | $-5M | $-7M | $-5M | $-5M | $-5M | $-7M | $-5M | $-5M | $-12M | $-5M | $-4M | $3M | $682.0K | |
| CapEx | $0 | $0 | $6.0K | $8.0K | $5.0K | $9.0K | $2.0K | $6.0K | $0 | $0 | $0 | · | · | $0 | $-169.0K | $0 | |
| Investing Cash Flow | $42.0K | $2M | $7M | $4M | $134.0K | $-1M | $-5M | $9M | $5M | $-13M | $-3M | $10M | $5M | $0 | $-11M | $-2M | |
| Stock Issued | $12M | $0 | $0 | $0 | $0 | $8.0K | $9M | $0 | $-60.0K | $19M | $0 | $0 | $10M | · | · | · | |
| Net Stock Activity | · | $0 | · | · | · | $8.0K | · | · | · | $19M | · | · | $10M | · | · | · | |
| Financing Cash Flow | $15M | $0 | $4M | $818.0K | $-102.0K | $11M | $9M | $16.0K | $-7.0K | $19M | $72.0K | $-3M | $24M | $5M | $3M | $1M | |
| Net Change in Cash | $10M | $-3M | $6M | $-448.0K | $-7M | $5M | $-1M | $4M | $-2M | $1M | $-7M | $-5M | $23M | $1M | $-5M | $465.0K | |
| Free Cash Flow | · | $-5M | · | · | · | $-5M | · | · | · | · | · | · | · | · | · | · |
Profitability 5
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -7429.6% | -5293.4% | · | -4012.9% | -3009.6% | -3216.3% | · | · | · | · | · | · | · | · | · | · | |
| Net Margin | -14170.4% | 4694.3% | · | -5574.3% | -2707.3% | -2496.0% | · | · | · | · | · | · | · | · | · | · | |
| EBITDA Margin | -7429.6% | -5293.4% | · | -4012.9% | -3009.6% | -3216.3% | · | · | · | · | · | · | · | · | · | · | |
| ROA | -39.7% | 29.3% | · | -50.1% | -29.7% | -19.2% | · | -35.0% | -19.1% | 0.42% | -15.1% | -17.0% | -40.5% | · | -16.1% | -12.0% | |
| ROE | -131.8% | 101.7% | · | -178.1% | -59.7% | -35.8% | · | -53.0% | -26.3% | 0.66% | -17.2% | -19.1% | -49.3% | · | -17.2% | -12.8% |
Liquidity & Solvency 2
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.6 | 1.6 | · | 4.0 | 5.5 | 5.7 | · | 4.1 | 5.2 | 6.2 | 4.1 | 5.0 | 2.7 | · | 12.0 | 11.9 | |
| Quick Ratio | 5.3 | 1.5 | · | 3.8 | 5.2 | 5.5 | · | 3.9 | 4.9 | 6.0 | 4.0 | 4.7 | 2.7 | · | 11.6 | 11.7 |
Efficiency 1
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | · | · | · | · | · | · | · | · | · |
Valuation (TTM) 10
| Metric | Trend | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $520.0K | $668.0K | · | $780.0K | $915.0K | $1M | · | · | · | · | · | · | · | · | · | · | |
| Net Income TTM | $-16M | $-14M | · | $-24M | $-21M | $-14M | · | $-14M | $-15M | $-30M | $-33M | $-31M | $-29M | · | $-17M | $-22M | |
| Market Cap | $32M | $9M | · | $44M | $22M | $27M | · | $48M | $43M | $45M | $15M | $23M | · | · | · | · | |
| P/E | -1.0 | -0.6 | · | -1.7 | -1.0 | -1.6 | · | -2.7 | -1.7 | -0.2 | -0.0 | -0.0 | · | · | · | · | |
| P/S | 60.9 | 12.7 | · | 56.2 | 24.4 | 26.6 | · | · | · | · | · | · | · | · | · | · | |
| P/B | 5.7 | -7.7 | · | -163.6 | 3.7 | 2.5 | · | 5.3 | 3.1 | 2.6 | 1.2 | 1.4 | · | · | · | · | |
| P / Tangible Book | 5.7 | · | · | · | 3.7 | 2.5 | · | 5.3 | 3.1 | 2.6 | 1.2 | 1.4 | · | · | · | · | |
| P / Cash Flow | · | -1.8 | · | · | · | -5.5 | · | · | · | -9.5 | · | · | · | · | · | · | |
| P / FCF | · | -1.8 | · | · | · | -5.5 | · | · | · | · | · | · | · | · | · | · | |
| Earnings Yield | -103.9% | -181.5% | · | -57.9% | -101.2% | -63.3% | · | -37.7% | -57.6% | -609.4% | -2120.3% | -2297.5% | · | · | · | · |
Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years
Income Statement
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Net Income | $-30M | $-14M | $-34M | $-8M | $-36M |
| Diluted EPS | $-1.97 | $-1.22 | $-7.66 | $-111.16 | $-1.69 |
Balance Sheet
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Current Ratio | — | 5.3 | — | — | 16.5 |
| Quick Ratio | — | 5.1 | — | — | 15.7 |
Cash Flow
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Free Cash Flow | — | $-21M | — | — | $-32M |
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Institutional owners (13F) 35 filers · $11.1M total · As of June 30, 2026
Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.
Institutional activity — Q2 2026 vs prior quarter
| New positions | Exited positions | Increased | Decreased | Net shares change |
|---|---|---|---|---|
| 12 (+2 vs prior Q) | 6 (-6 vs prior Q) | 5 (0 vs prior Q) | 6 (+2 vs prior Q) | +7.4M |
Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.
| Institution | Value | Shares | % of tracked 13F | Type |
|---|---|---|---|---|
| Woodline Partners LP | $2,564,421 | 2,489,729 | 23.15% | Shares |
| VANGUARD GROUP INC | $2,346,916 | 356,133 | 21.19% | Shares |
| HEIGHTS CAPITAL MANAGEMENT, INC | $1,602,763 | 1,556,081 | 14.47% | Shares |
| Squadron Capital Management LLC | $1,282,210 | 1,244,864 | 11.57% | Shares |
| STEMPOINT CAPITAL LP | $1,195,661 | 1,244,864 | 10.79% | Shares |
| Stonepine Capital Management, LLC | $544,939 | 622,432 | 4.92% | Shares |
| MERITAGE PORTFOLIO MANAGEMENT | $405,542 | 61,539 | 3.66% | Shares |
| L1 Global Manager Pty Ltd | $256,441 | 248,972 | 2.31% | Shares |
| Sheets Smith Investment Management | $157,173 | 51,100 | 1.42% | Shares |
| RENAISSANCE TECHNOLOGIES LLC | $100,219 | 97,300 | 0.90% | Shares |
| GEODE CAPITAL MANAGEMENT, LLC | $93,441 | 90,666 | 0.84% | Shares |
| VANGUARD CAPITAL MANAGEMENT LLC | $91,625 | 88,956 | 0.83% | Shares |
| 180 WEALTH ADVISORS, LLC | $85,902 | 83,400 | 0.78% | Shares |
| XTX Topco Ltd | $80,637 | 78,288 | 0.73% | Shares |
| CITADEL ADVISORS LLC | $73,954 | 71,800 | 0.67% | Call option |
| VANGUARD FIDUCIARY TRUST CO | $47,204 | 45,829 | 0.43% | Shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $45,287 | 43,968 | 0.41% | Shares |
| Rockefeller Capital Management L.P. | $20,600 | 20,000 | 0.19% | Shares |
| STATE STREET CORP | $17,585 | 17,073 | 0.16% | Shares |
| TritonPoint Partners, LLC | $15,573 | 15,119 | 0.14% | Shares |
| Scientech Research LLC | $15,558 | 15,105 | 0.14% | Shares |
| NORTHERN TRUST CORP | $12,906 | 12,530 | 0.12% | Shares |
| Sound View Wealth Advisors Group, LLC | $10,300 | 10,000 | 0.09% | Shares |
| SIMPLEX TRADING, LLC | $4,864 | 4,723 | 0.04% | Shares |
| Tower Research Capital LLC (TRC) | $4,227 | 4,104 | 0.04% | Shares |
| MORGAN STANLEY | $1,289 | 1,251 | 0.01% | Shares |
| BROWN BROTHERS HARRIMAN & CO | $317 | 308 | 0.00% | Shares |
| BARCLAYS PLC | $282 | 274 | 0.00% | Shares |
| OSAIC HOLDINGS, INC. | $110 | 107 | 0.00% | Shares |
| SBI Securities Co., Ltd. | $90 | 87 | 0.00% | Shares |
| Cambridge Investment Research Advisors, Inc. | $62 | 60,000 | 0.00% | Shares |
| HRT FINANCIAL LP | $48 | 46,825 | 0.00% | Shares |
| GSA CAPITAL PARTNERS LLP | $18 | 17,469 | 0.00% | Shares |
| UBS Group AG | $16 | 16 | 0.00% | Shares |
| WELLS FARGO & COMPANY/MN | $10 | 10 | 0.00% | Shares |
Company insiders 21 insiders · 10 officers · 14 directors
| Insider | Role | Last activity | Shares owned | Buys 12m | Sells 12m | Net 12m |
|---|---|---|---|---|---|---|
| Rachel A. Leheny | CHIEF EXECUTIVE OFFICER | June 25, 2026 A | 317,655 | 0 | 0 | $0 |
| Frederic Guerard | Chief Executive Officer | March 23, 2023 D | 90,727 | 0 | 0 | $0 |
| Robert S Breuil | Chief Financial Officer | March 23, 2023 D | 35,326 | 0 | 0 | $0 |
| Daniel E. Geffken | Interim CFO | March 20, 2023 A | — | 0 | 0 | $0 |
| Michael J. Dunn | President and COO | May 8, 2023 A | — | 0 | 0 | $0 |
| Sudarshan Hebbar | Chief Medical Officer | June 25, 2026 A | 186,025 | 0 | 0 | $0 |
| Eric W Roberts | CHIEF BUSINESS OFFICER | June 25, 2026 A | 366,435 | 0 | 0 | $0 |
| Kenneth A. Stauderman | Chief Scientific Officer | May 8, 2023 A | 11,944 | 0 | 0 | $0 |
| Parisa Zamiri | Chief Medical Officer | March 23, 2023 D | 28,982 | 0 | 0 | $0 |
| Daniel Salain | CTOO | Dec. 8, 2020 A | — | 0 | 0 | $0 |
| Evgeny Zaytsev | Director | July 2, 2026 A | — | 0 | 0 | $0 |
| Fred A Middleton | Director | June 25, 2026 P | 1,063,272 | 1 | 0 | $199,178 |
| Robert N Wilson | Director | June 25, 2026 A | 1,604,650 | 0 | 0 | $0 |
| Allan Shaw | Director | May 8, 2023 A | — | 0 | 0 | $0 |
| Eric Bjerkholt | Director | May 8, 2023 A | 3,684 | 0 | 0 | $0 |
| Dirk Sauer | Director | March 23, 2023 D | 1,429 | 0 | 0 | $0 |
| Christina Ackermann | Director | March 23, 2023 D | 1,429 | 0 | 0 | $0 |
| Julia Marie Eastland | Director | March 23, 2023 D | 1,429 | 0 | 0 | $0 |
| Christy L Shaffer | Director | March 23, 2023 D | 1,429 | 0 | 0 | $0 |
| Gerald D. Cagle | Director | June 2, 2021 A | 3,322 | 0 | 0 | $0 |
| Hansoo Michael Keyoung | Director | Sept. 29, 2020 C | 1,133,596 | 0 | 0 | $0 |
Insiders from SEC Form 3/4/5 filings; net = open-market P/S only
Activists & 5%+ owners 5 positions
Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.
| Filer | Filed | Stake | Status | Purpose | Filing |
|---|---|---|---|---|---|
| Bering Partners II GP, L.L.C., Bering Partners II, L.P., Evgeny Zaytsev, Philip M Sawyer | July 2, 2026 | 6.90% | Initial filing | — | SEC |
| Valence Investments SPV IV, LLC, Valence Investments SPV V, LLC, Valence Investments SPV VI, LLC, Eric W. Roberts, A. Rachel Leheny ×5 filings | June 30, 2026 | 6.40% | Amendment | — | SEC |
| Sanderling Ventures Partners VI, L.P., Sanderling Venture Partners VI Co-Investment Fund, L.P., Sanderling Ventures VII, L.P., Sanderling Ventures VII (Canada), L.P., Sanderling Ventures VII Annex Fund, L.P., Sanderling Ventures Management VI, Sanderling Ventures Management VII, Sanderling VI Beteiligungs GmbH & Co KG, Sanderling VI Limited Partnership, Fred A. Middleton, Timothy C. Mills | Nov. 26, 2024 | — | Initial filing | — | SEC |
| OrbiMed Advisors LLC, OrbiMed Capital GP VI LLC ×4 filings | Feb. 5, 2024 | — | Initial filing | — | SEC |
| Deerfield Mgmt III, L.P., Deerfield Private Design Fund III, L.P., Deerfield Mgmt HIF, L.P., Deerfield Healthcare Innovations Fund, L.P., Deerfield Mgmt, L.P., Deerfield Partners, L.P., Deerfield Management Company, L.P., James E. Flynn ×6 filings | May 23, 2023 | — | Initial filing | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.