CALC Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

03
Price $1.60
Market Cap (MRQ) $49M
P/E -3.3
EPS $-1.97
52W Range $2–$36

CALC Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

04
range
bars

Bar granularity adapts to the selected period — hover the chart to see open/high/low/close for a bar.

Stock splits 1
Ex-date Split Type
Aug. 31, 2026 1-for-5 Reverse

10-Year Performance Revenue, net income, margins and EPS trends

06
EPS$-1.97
2021-12-31 → 2025-12-31
Free Cash Flow·
2020-12-31 → 2024-12-31
Valuation & Ratios 07–12

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric 5Y trend CALC 5Y avg Peer Median Verdict
P/E -3.35Y avg ≈-2.2 ≈-2.2 · ·
P/B (MRQ) 8.9 · 2.1 Overvalued
Price / FCF (TTM) -2.6 · · ·
Price / Cash Flow (TTM) -2.6 · · ·
Price / Tangible Book 3.3 · · ·

Peer median is calculated on a standardized basis per metric and may not always match the TTM/MRQ basis shown for this stock.

value · ≈ 5Y avg · industry median · verdict relative to median

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

14
Avg Surprise 2.9%
Next Report Nov 10, 2026
PeriodReportEPS ActualEPS EstSurprise
June 30, 2026 Aug 18, 2026 $-2.25 $-1.45 -54.8%
March 31, 2026 May 18, 2026 $1.50 $-1.43 205.0%
Dec. 31, 2025 $-3.65 $-2.10 -73.5%
Sept. 30, 2025 $-2.60 $-2.10 -23.6%
June 30, 2025 $-0.40 $-0.36 -12.0%
March 31, 2025 $-0.36 $-0.31 -15.1%
Dec. 31, 2024 $-0.38 $-0.36 -5.7%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

15
Income Statement 14
Metric Trend 2025202420232022202120202019
R&D Expense $15M$14M$16M$8M$19M$21M$31M
SG&A Expense $8M$10M$22M$6M$17M$9M$7M
Operating Expenses $23M$24M$38M$14M$36M$30M$38M
Operating Income $-23M$-24M$-38M$-14M$-36M$-30M$-38M
Interest Income ···$575.0K$126.0K$143.0K$393.0K
Other Non-op $268.0K$0$550.0K$-28.0K···
Pretax Income $-30M$-14M·····
Income Tax $0$0$1.0K$1.0K···
Net Income $-30M$-14M$-34M$-8M$-36M$-28M$-37M
EPS (Basic) $-1.97$-1.22$-7.66$-111.16$-1.69··
EPS (Diluted) $-1.97$-1.22$-7.66$-111.16$-1.69··
Shares (Basic) 15,011,32111,245,9154,486,25882,24521,199,291··
Shares (Diluted) 15,011,32111,245,9154,486,25882,24521,199,291··
EBITDA ·$-24M··$-36M$-30M·
Balance Sheet 19
Metric Trend 2025202420232022202120202019
Cash & Equivalents $12M$8M$6M$1M$13M$33M$16M
Short-term Investments $1M$11M$6M$0$50M$62M$20M
Prepaid Expense $259.0K$248.0K$296.0K$254.0K$3M$4M$315.0K
Other Current Assets ····$1M$1M·
Current Assets $14M$20M$12M$2M$67M$99M$36M
PP&E (Net) $50.0K$119.0K$167.0K$147.0K$2M$2M$2M
PP&E (Gross) ····$4M$3M$3M
Accum. Depreciation ····$2M$1M$739.0K
Total Assets $14M$20M$12M$3M$69M$102M$41M
Accounts Payable $1M$2M$1M$3M$527.0K$3M$5M
Accrued Liabilities ···$200.0K$304.0K$1M$2M
Current Liabilities $4M$4M$4M$5M$4M$7M$12M
Total Liabilities $20M$5M$4M$13M$4M$7M$12M
Common Stock $4.0K$4.0K$1.0K$1.0K$2.0K$2.0K·
Retained Earnings $-189M$-160M$-146M$-112M$-169M$-133M$-106M
AOCI $0$4.0K$2.0K$-37.0K$-16.0K$-4.0K$3.0K
Stockholders' Equity $-7M$14M$8M$-71M$-64M$95M$-103M
Liabilities + Equity $14M$20M$12M$3M$69M$102M$41M
Shares Outstanding 15,437,41013,481,9175,754,50584,16521,357,77320,979,2651,371,467
Cash Flow 12
Metric Trend 2025202420232022202120202019
D&A ··$58.0K$52.0K···
Stock-based Comp $3M$2M$12M$2M$5M$2M$738.0K
Restructuring ···$3M···
Operating Cash Flow $-21M$-21M$-26M$-12M$-32M$-32M$-31M
CapEx $28.0K$8.0K$78.0K$4.0K$488.0K$1M$605.0K
Investing Cash Flow $10M$-4M$9M$-4.0K$11M$-43M$-21M
Stock Issued $8.0K$28M$10M··$96M·
Net Stock Activity ·$28M···$96M·
Financing Cash Flow $15M$28M$21M$8M$695.0K$92M$55M
Net Change in Cash $4M$2M$4M$-3M$-20M$18M$3M
Taxes Paid $0······
Free Cash Flow ·$-21M··$-32M$-33M·
Profitability 2
Metric Trend 2025202420232022202120202019
ROA ·-85.7%··-41.9%-38.6%·
ROE ·-116.9%··-52.2%-29.7%·
Liquidity & Solvency 2
Metric Trend 2025202420232022202120202019
Current Ratio ·5.3··16.514.2·
Quick Ratio ·5.1··15.713.6·
Per Share 4
Metric Trend 2025202420232022202120202019
Book Value / Share ·$1.07··$3.04$4.52·
Cash Flow / Share ·$-1.88·····
Cash / Share ·$0.59··$0.63$1.59·
EPS (TTM) $-1.97$-1.22$-7.66$-111.16$-1.69··
Growth Rates 1
Metric Trend 2025202420232022202120202019
Revenue YoY -29.7%······
Valuation (TTM) 10
Metric Trend 2025202420232022202120202019
Revenue TTM $713.0K$1M·····
Net Income TTM $-30M$-14M$-34M$-8M$-36M$-28M·
Market Cap ·$48M·····
P/E -3.3-2.9-0.4····
P/S ·47.1·····
P/B ·3.3·····
P / Tangible Book ·3.32.0····
P / Cash Flow ·-2.3·····
P / FCF ·-2.3·····
Earnings Yield -29.9%-34.5%-267.8%····

Most recent period on the left · null values shown as ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

16
Metric 2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-30M $-14M $-34M $-8M $-36M
Diluted EPS $-1.97 $-1.22 $-7.66 $-111.16 $-1.69

Institutional owners (13F) 35 filers · $11.6M total · As of June 30, 2026

17

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Holders 35
Value held $11.6M
New positions 10
Exited positions 6
Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
10 (-2 vs prior Q) 6 (-6 vs prior Q) 5 (+1 vs prior Q) 7 (+2 vs prior Q) +7.3M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
VANGUARD GROUP INC $2,687,408 407,801 23.20% Shares
Woodline Partners LP $2,564,421 2,489,729 22.14% Shares
HEIGHTS CAPITAL MANAGEMENT, INC $1,602,763 1,556,081 13.83% Shares
Squadron Capital Management LLC $1,282,210 1,244,864 11.07% Shares
STEMPOINT CAPITAL LP $1,195,661 1,244,864 10.32% Shares
Stonepine Capital Management, LLC $544,939 622,432 4.70% Shares
MERITAGE PORTFOLIO MANAGEMENT $405,542 61,539 3.50% Shares
L1 Global Manager Pty Ltd $256,441 248,972 2.21% Shares
Sheets Smith Investment Management $157,173 51,100 1.36% Shares
MORGAN STANLEY $147,543 143,245 1.27% Shares
GEODE CAPITAL MANAGEMENT, LLC $113,846 110,477 0.98% Shares
RENAISSANCE TECHNOLOGIES LLC $100,219 97,300 0.87% Shares
VANGUARD CAPITAL MANAGEMENT LLC $91,625 88,956 0.79% Shares
180 WEALTH ADVISORS, LLC $85,902 83,400 0.74% Shares
XTX Topco Ltd $80,637 78,288 0.70% Shares
CITADEL ADVISORS LLC $73,954 71,800 0.64% Call option
VANGUARD FIDUCIARY TRUST CO $47,204 45,829 0.41% Shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP $45,287 43,968 0.39% Shares
Rockefeller Capital Management L.P. $20,600 20,000 0.18% Shares
STATE STREET CORP $17,585 17,073 0.15% Shares
TritonPoint Partners, LLC $15,573 15,119 0.13% Shares
Scientech Research LLC $15,558 15,105 0.13% Shares
NORTHERN TRUST CORP $12,906 12,530 0.11% Shares
Sound View Wealth Advisors Group, LLC $10,300 10,000 0.09% Shares
SIMPLEX TRADING, LLC $4,864 4,723 0.04% Shares
Tower Research Capital LLC (TRC) $4,227 4,104 0.04% Shares
BROWN BROTHERS HARRIMAN & CO $317 308 0.00% Shares
BARCLAYS PLC $282 274 0.00% Shares
OSAIC HOLDINGS, INC. $110 107 0.00% Shares
SBI Securities Co., Ltd. $90 87 0.00% Shares
Cambridge Investment Research Advisors, Inc. $62 60,000 0.00% Shares
HRT FINANCIAL LP $48 46,825 0.00% Shares
GSA CAPITAL PARTNERS LLP $18 17,469 0.00% Shares
UBS Group AG $16 16 0.00% Shares
WELLS FARGO & COMPANY/MN $10 10 0.00% Shares

Activists & 5%+ owners 6 positions

18

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Alafi Capital Company LLC, Christopher D. Alafi ×2 filings Aug. 24, 2026 19.90% Amendment · SEC
Bering Partners II GP, L.L.C., Bering Partners II, L.P., Evgeny Zaytsev, Philip M Sawyer ×2 filings Aug. 21, 2026 9.99% Amendment · SEC
Valence Investments SPV IV, LLC, Valence Investments SPV V, LLC, Valence Investments SPV VI, LLC, Eric W. Roberts, A. Rachel Leheny ×5 filings June 30, 2026 6.40% Amendment · SEC
Sanderling Ventures Partners VI, L.P., Sanderling Venture Partners VI Co-Investment Fund, L.P., Sanderling Ventures VII, L.P., Sanderling Ventures VII (Canada), L.P., Sanderling Ventures VII Annex Fund, L.P., Sanderling Ventures Management VI, Sanderling Ventures Management VII, Sanderling VI Beteiligungs GmbH & Co KG, Sanderling VI Limited Partnership, Fred A. Middleton, Timothy C. Mills Nov. 26, 2024 · Initial filing · SEC
OrbiMed Advisors LLC, OrbiMed Capital GP VI LLC ×4 filings Feb. 5, 2024 · Initial filing · SEC
Deerfield Mgmt III, L.P., Deerfield Private Design Fund III, L.P., Deerfield Mgmt HIF, L.P., Deerfield Healthcare Innovations Fund, L.P., Deerfield Mgmt, L.P., Deerfield Partners, L.P., Deerfield Management Company, L.P., James E. Flynn ×6 filings May 23, 2023 · Initial filing · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Company insiders 24 insiders · 10 officers · 15 directors

19
Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Rachel A. Leheny CHIEF EXECUTIVE OFFICER Sept. 24, 2026 A 317,655 0 0 $0
Stephen Bardin Chief Financial Officer Sept. 24, 2026 A 3,000 0 0 $0
Daniel E. Geffken Interim CFO May 17, 2024 A · 0 0 $0
Robert S Breuil Chief Financial Officer March 23, 2023 D 35,326 0 0 $0
Michael J. Dunn President and COO April 5, 2025 A 11,761 0 0 $0
Kenneth A. Stauderman Chief Scientific Officer Sept. 24, 2026 A 12,944 0 0 $0
Sudarshan Hebbar Chief Medical Officer Sept. 24, 2026 A 186,025 0 0 $0
Eric W Roberts CHIEF BUSINESS OFFICER Aug. 19, 2026 A 366,435 0 0 $0
Parisa Zamiri Chief Medical Officer March 23, 2023 D 28,982 0 0 $0
Daniel Salain CTOO Dec. 8, 2020 A · 0 0 $0
Frederic Guerard Director Aug. 19, 2026 A 90,727 0 0 $0
Alan Glicklich Director Aug. 19, 2026 A · 0 0 $0
Evgeny Zaytsev Director Aug. 19, 2026 A · 0 0 $0
Allan Shaw Director Aug. 19, 2026 A · 0 0 $0
Robert N Wilson Director Aug. 19, 2026 A 1,604,650 0 0 $0
Fred A Middleton Director June 25, 2026 P 1,063,272 1 0 $199,178
Eric Bjerkholt Director Aug. 27, 2024 A 3,684 0 0 $0
Dirk Sauer Director March 23, 2023 D 1,429 0 0 $0
Christina Ackermann Director March 23, 2023 D 1,429 0 0 $0
Julia Marie Eastland Director March 23, 2023 D 1,429 0 0 $0
Christy L Shaffer Director March 23, 2023 D 1,429 0 0 $0
Gerald D. Cagle Director June 2, 2021 A 3,322 0 0 $0
Hansoo Michael Keyoung Director Sept. 29, 2020 C 1,133,596 0 0 $0
Alafi Capital Company LLC 10% owner Aug. 19, 2026 A · 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

CALC Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

21
rating · 10 analysts BUY
Median target $45.00 +2712.5%
3 30.0% Strong Buy
5 50.0% Buy
2 20.0% Hold
0 0.0% Sell
0 0.0% Strong Sell

12-Month Price Target

3 analysts · 2026-09-30

Mean target $50.00 +3025.0%

← Below all targets Current price $1.60
Low$30.00 Mean$50.00 High$75.00

Peer comparison (GICS sub-industry) Key metrics vs sector peers

22

FY basis, prices as of each company's last fiscal year-end close.

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
CALC · -3.3 -29.7% · · ·
BFRI · · · · · ·
CTXR · -0.4 · · · ·
HIND $20M -0.7 24.4% -3209.7% -411.1% 68.4%
KPRX $7M -0.7 · · -56.6% ·
ADIL $244.4K -0.0 · · -146.8% ·
TRAW · 1.4 1134.5% · · ·
JAGX · -0.0 -1.5% -465.4% 907.4% ·

My Metrics Your personal watchlist — selected rows from Full Fundamentals

26

Pick the metrics that matter to you — click the + next to any row in Full Fundamentals above.

Your selection is saved and follows you across all tickers.

Source: SEC 10-Q filed Aug 11, 2026