PCRX Pacira BioSciences, Inc. - Common Stock

NASDAQ · Pharmaceuticals · View on SEC EDGAR ↗
$23.49
Price · Aug 18, 2026
Fundamentals as of Aug 4, 2026

PCRX Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$23.48
Market Cap
$1.13B
P/E (TTM)
172.5
EPS (TTM)
$0.16
Revenue (TTM)
$726M
Div Yield
ROE
0.97%
Debt/Equity
0.5
52W Range
$19 – $28

PCRX Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $726M
10-point trend, +162.8%
2016-12-31 2025-12-31
EPS $0.16
10-point trend, +115.7%
2016-12-31 2025-12-31
Free Cash Flow $137M
10-point trend, +1462.9%
2016-12-31 2025-12-31
Margins 0.97%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
PCRX
Peer Median
P/E (TTM)
5-point trend, +147.3%
172.5
29.9
P/S (TTM)
5-point trend, -70.5%
1.6
14.4
P/B
5-point trend, -58.3%
1.6
4.4
EV / EBITDA
2-point trend, +118.0%
11.5
Price / FCF
5-point trend, -76.9%
8.3

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
PCRX
Peer Median
Operating Margin
5-point trend, -75.5%
2.6%
Net Profit Margin
5-point trend, -97.1%
0.97%
0.70%
ROA
5-point trend, -80.1%
0.50%
-0.55%
ROE
5-point trend, -83.2%
0.97%
-2.5%
ROIC
5-point trend, -91.8%
0.75%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
PCRX
Peer Median
Debt / Equity
2-point trend, -0.8%
0.5
Current Ratio
5-point trend, +173.4%
4.5
3.9
Quick Ratio
5-point trend, +108.1%
3.0

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
PCRX
Peer Median
Revenue YoY
5-point trend, +34.1%
3.6%
Revenue CAGR 3Y
5-point trend, +34.1%
2.9%
Revenue CAGR 5Y
5-point trend, +34.1%
11.1%
EPS YoY
5-point trend, -82.6%
161.8%
Net Income YoY
5-point trend, -83.2%
163.7%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
PCRX
Peer Median
EPS (Diluted)
5-point trend, -82.6%
$0.16

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
PCRX
Peer Median

PCRX Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 12 analysts
  • Strong Buy 3 25.0%
  • Buy 5 41.7%
  • Hold 3 25.0%
  • Sell 1 8.3%
  • Strong Sell 0 0.0%

12-Month Price Target

6 analysts · 2026-08-13
Median target $29.00 +23.5%
Mean target $30.00 +27.7%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
-0.03%
Period EPS Actual EPS Est Surprise
June 30, 2026 $0.73 $0.66 0.07%
March 31, 2026 $0.60 $0.57 0.03%
Dec. 31, 2025 $0.57 $0.92 -0.35%
Sept. 30, 2025 $0.70 $0.66 0.04%
June 30, 2025 $0.74 $0.72 0.02%
March 31, 2025 $0.62 $0.61 0.01%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
PCRX $1.06B 161.8 3.6% 0.97% 0.97%
OMER $1.23B -343.6 1.9%
LXRX $421M -8.2 60.2% -101.1% -39.7%
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
AMPH $1.22B 13.2 -1.7% 13.6% 12.7% 49.5%
ACRS $363M -5.7 -58.2% -829.6% -55.3%
SGP 50.0%
PHAT $1.18B -5.5 216.9% -126.4% 52.4% 87.1%
LLY 46.8 44.7% 31.7% 101.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 17
Annual Income Statement data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +267.5% $726M $701M $675M $667M $542M $430M $421M $337M $287M $276M $249M $198M
Cost of Revenue 12-point trend, +93.4% $150M $170M $185M $199M $140M $117M $107M $87M $88M $110M $72M $77M
R&D Expense 12-point trend, +526.3% $117M $82M $76M $85M $56M $59M $72M $56M $57M $46M $29M $19M
SG&A Expense 12-point trend, +245.7% $369M $294M $269M $255M $199M $194M $201M $177M $161M $153M $139M $107M
Operating Expenses 12-point trend, +248.7% $707M $774M $587M $607M $452M $383M $411M $321M $312M $308M $240M $203M
Operating Income 12-point trend, +471.6% $19M $-73M $88M $60M $90M $46M $10M $16M $-25M $-32M $9M $-5M
Interest Expense 10-point trend, +145.3% · · $20M $40M $32M $26M $24M $22M $18M $7M $8M $8M
Interest Income 12-point trend, +5850.8% $23M $20M $11M $5M $896.0K $5M $7M $6M $4M $1M $678.0K $382.0K
Other Non-op 12-point trend, -4063.5% $-7M $-373.0K $-186.0K $-11M $-3M $3M $-5M $-888.0K $167.0K $-82.0K $-165.0K $-159.0K
Pretax Income 12-point trend, +224.6% $17M $-63M $62M $13M $56M $20M $-11M $-425.0K $-42M $-38M $2M $-14M
Income Tax 12-point trend, +5587.9% $10M $36M $20M $-3M $14M $-125M $268.0K $46.0K $140.0K $105.0K $264.0K $173.0K
Net Income 12-point trend, +151.3% $7M $-100M $42M $16M $42M $146M $-11M $-471.0K $-43M $-38M $2M $-14M
EPS (Basic) 12-point trend, +141.0% $0.16 $-2.15 $0.91 $0.35 $0.95 $3.41 $-0.27 $-0.01 $-1.07 $-1.02 $0.05 $-0.39
EPS (Diluted) 12-point trend, +141.0% $0.16 $-2.15 $0.89 $0.34 $0.92 $3.33 $-0.27 $-0.01 $-1.07 $-1.02 $0.04 $-0.39
Shares (Basic) 12-point trend, +26.3% 44,566,000 46,245,000 46,222,000 45,521,000 44,262,000 42,671,000 41,513,000 40,911,000 39,806,000 37,236,000 36,540,000 35,299,000
Shares (Diluted) 12-point trend, +27.6% 45,042,000 46,245,000 51,979,000 46,538,000 45,630,000 43,682,000 41,513,000 40,911,000 39,806,000 37,236,000 41,301,000 35,299,000
EBITDA 12-point trend, +2163.1% $110M $5M $163M $152M $118M $66M $30M $29M $-11M $-19M $21M $5M
Balance Sheet 30
Annual Balance Sheet data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +322.6% $159M $277M $153M $104M $586M $100M $78M $133M $54M $36M $54M $38M
Short-term Investments 12-point trend, -33.0% $80M $208M $125M $185M $71M $422M $214M $251M $257M $137M $102M $119M
Receivables 12-point trend, +454.7% $124M $113M $106M $98M $96M $53M $48M $38M $32M $30M $26M $22M
Inventory 12-point trend, +422.4% $153M $125M $104M $96M $99M $65M $58M $49M $41M $31M $62M $29M
Prepaid Expense 12-point trend, +631.2% $33M $22M $22M $15M $15M $12M $11M $8M $7M $9M $6M $4M
Current Assets 12-point trend, +155.8% $548M $745M $510M $498M $866M $652M $409M $478M $391M $243M $253M $214M
PP&E (Net) 12-point trend, +132.0% $141M $167M $174M $184M $188M $137M $105M $109M $107M $101M $90M $61M
PP&E (Gross) 12-point trend, +244.8% $278M $300M $309M $301M $274M $215M $180M $170M $156M $139M $115M $81M
Accum. Depreciation 12-point trend, +584.6% $138M $133M $135M $117M $85M $78M $75M $62M $49M $38M $25M $20M
Goodwill 12-point trend, -14.9% $20M $0 $163M $163M $145M $100M $100M $62M $55M $47M $31M $24M
Intangibles 11-point trend, +91240.0% $368M $426M $483M $541M $624M $97M $104M $0 · $0 $81.0K $403.0K
Other Non-current Assets 5-point trend, -74.6% · · · · · · · $657.0K $825.0K $624.0K $406.0K $3M
Total Assets 12-point trend, +287.9% $1.26B $1.55B $1.57B $1.68B $2.08B $1.27B $831M $689M $628M $391M $388M $326M
Accounts Payable 12-point trend, +124.2% $15M $19M $16M $15M $11M $10M $13M $14M $15M $8M $9M $7M
Accrued Liabilities 12-point trend, +237.7% $96M $80M $64M $90M $128M $71M $70M $46M $41M $37M $35M $28M
Current Liabilities 12-point trend, -13.9% $121M $310M $97M $148M $521M $253M $108M $61M $56M $45M $150M $140M
Capital Leases 8-point trend, +36176000.00 $36M $45M $55M $65M $72M $71M $41M $0 · · · ·
Deferred Tax 2-point trend, +4213000.00 $4M $0 · · · · · · · · · ·
Other Non-current Liabilities 12-point trend, +280.3% $21M $17M $14M $10M $20M $4M $2M $17M $16M $19M $11M $5M
Total Liabilities 12-point trend, +269.1% $572M $775M $704M $906M $1.34B $655M $476M $368M $349M $172M $169M $155M
Long-term Debt 7-point trend, +261.0% $372M $585M $522M $689M · · · · · $109M $104M $103M
Total Debt 4-point trend, +210.2% $372M · · · · · · · · $119M $119M $120M
Common Stock 12-point trend, +33.3% $48.0K $47.0K $46.0K $46.0K $45.0K $44.0K $42.0K $41.0K $41.0K $37.0K $37.0K $36.0K
Paid-in Capital 12-point trend, +121.2% $1.06B $1.01B $977M $924M $942M $873M $754M $710M $669M $565M $527M $481M
Retained Earnings 12-point trend, +35.7% $-199M $-206M $-107M $-149M $-212M $-254M $-399M $-388M $-389M $-346M $-308M $-310M
Treasury Stock 3-point trend, +176565000.00 $177M $25M $0 · · · · · · · · ·
AOCI 12-point trend, +5508.8% $4M $343.0K $247.0K $-380.0K $167.0K $318.0K $322.0K $-280.0K $-454.0K $-30.0K $-52.0K $-80.0K
Stockholders' Equity 12-point trend, +305.0% $693M $778M $870M $775M $730M $620M $355M $321M $279M $219M $218M $171M
Liabilities + Equity 12-point trend, +287.9% $1.26B $1.55B $1.57B $1.68B $2.08B $1.27B $831M $689M $628M $391M $388M $326M
Shares Outstanding 12-point trend, +13.7% 41,116,739 47,078,000 46,481,000 45,928,000 44,734,000 43,637,000 41,908,148 41,222,799 40,668,877 37,480,952 36,848,319 36,150,620
Cash Flow 18
Annual Cash Flow data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, +807.1% $91M $79M $76M $92M $29M $20M $20M $13M $14M $13M $11M $10M
Stock-based Comp 12-point trend, +131.7% $58M $51M $48M $48M $42M $40M $34M $32M $32M $31M $33M $25M
Deferred Tax 9-point trend, +6477000.00 $6M $21M $16M $-8M $11M $-127M $-2M $0 $0 · · ·
Amort. of Intangibles 12-point trend, +7061.0% $57M $57M $57M $57M $14M $8M $6M $0 $0 $100.0K $300.0K $800.0K
Restructuring 8-point trend, +134.9% $4M $9M $1M $0 $0 $-38.0K $847.0K $2M · · · ·
Other Non-cash 12-point trend, -332.0% $-10M $138M $-26M $-2M $2M $-2M $30M $4M $15M $27M $-18M $4M
Operating Cash Flow 12-point trend, +472.2% $152M $189M $155M $145M $126M $77M $71M $49M $18M $33M $28M $27M
CapEx 12-point trend, -33.3% $15M $11M $15M $30M $46M $38M $10M $15M $19M $25M $40M $23M
Investing Cash Flow 9-point trend, +144.5% $99M $-83M $78M $-225M $-21M $-278M $-128M $21M $-224M · · ·
Debt Issued 3-point trend, -4000.00 · · · · · · · · · $-4.0K $-1M $0
Net Debt Issued 2-point trend, +99.7% · · · · · · · · · $-4.0K $-1M ·
Stock Repurchased 4-point trend, +148328000.00 $148M $25M $0 $0 · · · · · · · ·
Net Stock Activity 2-point trend, -493.3% $-148M $-25M · · · · · · · · · ·
Financing Cash Flow 9-point trend, -264.9% $-370M $17M $-183M $-402M $381M $222M $4M $9M $224M · · ·
Net Change in Cash 8-point trend, -250.8% $-118M $123M $49M $-481M $486M $22M $-54M $78M · · · ·
Taxes Paid 3-point trend, +104.8% $9M $11M $4M · · · · · · · · ·
Free Cash Flow 12-point trend, +3717.3% $137M $179M $139M $115M $80M $39M $60M $34M $-1M $9M $-12M $4M
Levered FCF 10-point trend, +2716.3% · · $126M $67M $56M $-147M $36M $10M $-20M $2M $-19M $-5M
Profitability 7
Annual Profitability data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +201.1% 2.6% · 13.0% 9.0% 16.6% 10.8% 2.5% 4.7% -8.7% -11.6% 3.8% -2.6%
Net Margin 11-point trend, +114.0% 0.97% · 6.2% 2.4% 7.8% 33.9% -2.6% -0.14% -14.9% -13.7% 0.75% -6.9%
Pretax Margin 11-point trend, +133.9% 2.3% · 9.1% 2.0% 10.4% 4.7% -2.5% -0.13% -14.8% -13.7% 0.85% -6.9%
EBITDA Margin 11-point trend, +516.7% 15.2% · 24.2% 22.7% 21.9% 15.4% 7.1% 8.6% -3.9% -6.9% 8.4% 2.5%
ROA 12-point trend, +109.0% 0.50% -6.4% 2.6% 0.85% 2.5% 13.8% -1.5% -0.07% -8.4% -9.7% 0.52% -5.5%
ROE 12-point trend, +107.5% 0.97% -13.0% 4.9% 2.1% 5.8% 24.2% -3.1% -0.15% -17.1% -17.3% 0.95% -12.9%
ROIC 12-point trend, +141.7% 0.75% -14.9% 6.9% 9.3% 9.2% 54.2% 3.0% 5.5% -8.9% -9.5% 2.5% -1.8%
Liquidity & Solvency 5
Annual Liquidity & Solvency data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 12-point trend, +196.9% 4.5 2.4 5.2 3.4 1.7 2.6 3.8 7.9 7.0 5.4 1.7 1.5
Quick Ratio 12-point trend, +135.1% 3.0 1.9 3.9 2.6 1.4 2.3 3.2 6.9 6.1 4.5 1.2 1.3
Debt / Equity 4-point trend, -23.4% 0.5 · · · · · · · · 0.5 0.5 0.7
LT Debt / Equity 0.5 · · · · · · · · · · ·
Interest Coverage 10-point trend, +792.1% · · 4.3 1.5 2.8 1.8 0.4 0.7 -1.4 -4.5 1.2 -0.6
Efficiency 3
Annual Efficiency data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, -35.3% 0.5 · 0.4 0.4 0.3 0.4 0.6 0.5 0.6 0.7 0.7 0.8
Inventory Turnover 12-point trend, -68.8% 1.1 1.5 1.8 2.0 1.7 1.9 2.0 1.9 2.4 2.4 1.6 3.5
Receivables Turnover 11-point trend, -42.8% 6.1 · 6.6 6.8 7.3 8.5 9.8 9.7 9.3 9.9 10.3 10.7
Per Share 5
Annual Per Share data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 12-point trend, +256.1% $16.86 $16.83 $18.72 $16.87 $16.33 $14.20 $8.47 $7.79 $6.87 $5.84 $5.93 $4.73
Revenue / Share 9-point trend, +167.5% $16.13 · $12.99 $14.33 $11.87 $9.84 $10.14 · $7.20 $7.42 $6.03 ·
Cash Flow / Share 10-point trend, +380.6% $3.37 $4.10 $2.98 $3.12 $2.76 $1.76 $1.70 · $0.45 $0.90 $0.70 ·
Cash / Share 12-point trend, +271.5% $3.86 $5.99 $3.30 $2.27 $13.09 $2.29 $1.87 $3.21 $1.33 $0.96 $1.55 $1.04
EPS (TTM) 12-point trend, +141.0% $0.16 $-2.15 $0.89 $0.34 $0.92 $3.33 $-0.27 $-0.01 $-1.07 $-1.02 $0.04 $-0.39
Growth Rates 9
Annual Growth Rates data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, -86.1% 3.6% 3.9% 1.2% 23.1% 26.0% · · · · · · ·
Revenue CAGR 3Y 3-point trend, -82.2% 2.9% 9.0% 16.2% · · · · · · · · ·
Revenue CAGR 5Y 11.1% · · · · · · · · · · ·
EPS YoY 3-point trend, +323.5% · · 161.8% -63.0% -72.4% · · · · · · ·
EPS CAGR 3Y 2-point trend, +37.6% -22.2% · -35.6% · · · · · · · · ·
EPS CAGR 5Y -45.5% · · · · · · · · · · ·
Net Income YoY 3-point trend, +330.1% · · 163.7% -62.1% -71.2% · · · · · · ·
Net Income CAGR 3Y 2-point trend, +29.8% -23.8% · -33.9% · · · · · · · · ·
Net Income CAGR 5Y -45.4% · · · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for PCRX
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +267.5% $726M $701M $675M $667M $542M $430M $421M $337M $287M $276M $249M $198M
Net Income TTM 12-point trend, +151.3% $7M $-100M $42M $16M $42M $146M $-11M $-471.0K $-43M $-38M $2M $-14M
Market Cap 12-point trend, -66.8% $1.06B $871M $1.57B $1.77B $2.69B $2.61B $1.90B $1.77B $1.86B $1.21B $2.83B $3.21B
Enterprise Value 4-point trend, -62.2% $1.20B · · · · · · · · $1.16B $2.79B $3.17B
P/E 12-point trend, +171.2% 161.8 -8.8 37.9 113.6 65.4 18.0 -167.8 -4302.0 -42.7 -31.7 1919.8 -227.3
P/S 12-point trend, -91.0% 1.5 1.2 2.3 2.7 5.0 6.1 4.5 5.3 6.5 4.4 11.4 16.2
P/B 12-point trend, -91.8% 1.5 1.1 1.8 2.3 3.7 4.2 5.3 5.5 6.6 5.5 13.0 18.7
P / Tangible Book 5-point trend, -43.4% 3.5 2.5 7.0 24.9 · 6.2 · · · · · ·
P / Cash Flow 12-point trend, -94.4% 7.0 4.6 10.1 12.2 21.4 33.9 26.9 36.3 104.4 36.2 97.6 125.8
P / FCF 12-point trend, -99.1% 7.8 4.9 11.2 15.4 33.7 66.6 31.5 51.6 -1253.6 138.5 -230.5 895.3
EV / EBITDA 4-point trend, -98.3% 10.9 · · · · · · · · -60.5 133.3 650.6
EV / FCF 4-point trend, -99.0% 8.8 · · · · · · · · 132.3 -227.2 885.0
EV / Revenue 4-point trend, -89.7% 1.6 · · · · · · · · 4.2 11.2 16.0
Earnings Yield 12-point trend, +240.9% 0.62% -11.4% 2.6% 0.88% 1.5% 5.6% -0.60% -0.02% -2.3% -3.2% 0.05% -0.44%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $726M$701M$675M$667M$542M
Operating Margin % 2.6%13.0%9.0%16.6%
Net Income $7M$-100M$42M$16M$42M
Diluted EPS $0.16$-2.15$0.89$0.34$0.92
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.5
Current Ratio 4.52.45.23.41.7
Quick Ratio 3.01.93.92.61.4
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $137M$179M$139M$115M$80M

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Institutional owners (13F) 267 filers · $788.9M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
42 (+13 vs prior Q) 23 (-17 vs prior Q) 78 (-4 vs prior Q) 74 (-7 vs prior Q) +4.6M

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
Doma Perpetual Capital Management LLC $70,472,634 2,777,794 8.93% Shares
VANGUARD PORTFOLIO MANAGEMENT LLC $61,046,258 2,406,238 7.74% Shares
STATE STREET CORP $52,261,616 2,059,977 6.62% Shares
DIMENSIONAL FUND ADVISORS LP $51,408,982 2,026,369 6.52% Shares
D. E. Shaw & Co., Inc. $48,394,315 1,907,541 6.13% Shares
RENAISSANCE TECHNOLOGIES LLC $43,986,531 1,733,801 5.58% Shares
VANGUARD CAPITAL MANAGEMENT LLC $42,915,156 1,691,571 5.44% Shares
GOLDMAN SACHS GROUP INC $29,790,215 1,174,230 3.78% Shares
AMERICAN CENTURY COMPANIES INC $25,829,019 1,018,093 3.27% Shares
GEODE CAPITAL MANAGEMENT, LLC $25,588,190 1,008,402 3.24% Shares
Impax Asset Management Group plc $19,028,185 750,027 2.41% Shares
TWO SIGMA INVESTMENTS, LP $18,383,203 724,604 2.33% Shares
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $17,525,241 690,786 2.22% Shares
GAGNON SECURITIES LLC $15,440,613 608,617 1.96% Shares
WELLINGTON MANAGEMENT GROUP LLP $12,178,564 480,038 1.54% Shares
BRIDGEWAY CAPITAL MANAGEMENT, LLC $10,436,533 411,373 1.32% Shares
Jefferies Financial Group Inc. $9,389,234 370,092 1.19% Shares
Hillsdale Investment Management Inc. $9,201,699 362,700 1.17% Shares
Gagnon Advisors, LLC $8,946,401 352,637 1.13% Shares
DEUTSCHE BANK AG\ $8,879,779 350,011 1.13% Shares
EASTERLY INVESTMENT PARTNERS LLC $8,550,172 337,019 1.08% Shares
Bridge City Capital, LLC $7,922,975 312,297 1.00% Shares
BARCLAYS PLC $7,825,936 308,472 0.99% Shares
VANGUARD GROUP INC $7,055,199 272,612 0.89% Shares
JPMORGAN CHASE & CO $6,850,197 273,025 0.87% Shares
VANGUARD FIDUCIARY TRUST CO $6,633,164 261,457 0.84% Shares
MILLENNIUM MANAGEMENT LLC $5,966,085 235,163 0.76% Shares
Coppell Advisory Solutions LLC $5,592,970 16 0.71% Shares
VICTORY CAPITAL MANAGEMENT INC $5,562,474 219,254 0.71% Shares
FMR LLC $5,499,658 216,778 0.70% Shares
BANK OF AMERICA CORP /DE/ $5,246,592 206,803 0.67% Shares
Empowered Funds, LLC $5,075,852 200,073 0.64% Shares
JACOBS LEVY EQUITY MANAGEMENT, INC $5,068,926 199,800 0.64% Shares
Banco Santander, S.A. $4,211,420 166,000 0.53% Shares
Robeco Institutional Asset Management B.V. $4,161,036 164,014 0.53% Shares
BlackRock, Inc. $3,645,035 143,675 0.46% Shares
AMERIPRISE FINANCIAL INC $3,591,503 141,565 0.46% Shares
Universal- Beteiligungs- und Servicegesellschaft mbH $3,562,811 140,434 0.45% Shares
Public Sector Pension Investment Board $3,429,720 135,188 0.43% Shares
PDT Partners, LLC $3,358,176 132,368 0.43% Shares
STATE OF WISCONSIN INVESTMENT BOARD $3,292,062 129,762 0.42% Shares
Man Group plc $3,180,637 125,370 0.40% Shares
MORGAN STANLEY $2,982,446 117,558 0.38% Shares
MARTINGALE ASSET MANAGEMENT L P $2,842,075 112,025 0.36% Shares
Assenagon Asset Management S.A. $2,573,254 101,429 0.33% Shares
RHUMBLINE ADVISERS $2,513,278 99,066 0.32% Shares
EXCHANGE TRADED CONCEPTS, LLC $2,505,592 98,762 0.32% Shares
TWO SIGMA ADVISERS, LP $2,453,424 94,800 0.31% Shares
RICE HALL JAMES & ASSOCIATES, LLC $2,369,457 93,396 0.30% Shares
Trexquant Investment LP $2,290,505 90,284 0.29% Shares
Simplify Asset Management Inc. $2,107,816 83,083 0.27% Shares
Vanguard Global Advisers, LLC $2,098,403 82,712 0.27% Shares
PRUDENTIAL FINANCIAL INC $2,022,065 79,703 0.26% Shares
Russell Investments Group, Ltd. $1,975,536 77,869 0.25% Shares
NORGES BANK $1,928,120 76,000 0.24% Shares
Swiss National Bank $1,907,824 75,200 0.24% Shares
NEW YORK STATE COMMON RETIREMENT FUND $1,857,997 73,236 0.24% Shares
CITADEL ADVISORS LLC $1,825,600 71,959 0.23% Shares
KLP KAPITALFORVALTNING AS $1,598,310 63,000 0.20% Shares
Three Seasons Wealth, LLC $1,596,839 62,942 0.20% Shares
ExodusPoint Capital Management, LP $1,546,631 60,963 0.20% Shares
Legal & General Group Plc $1,530,598 60,331 0.19% Shares
BNP PARIBAS FINANCIAL MARKETS $1,506,597 59,385 0.19% Shares
CAXTON ASSOCIATES LLP $1,443,984 56,917 0.18% Shares
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $1,385,516 61,306 0.18% Shares
MILESTONE ASSET MANAGEMENT, LLC $1,318,149 51,957 0.17% Shares
PRELUDE CAPITAL MANAGEMENT, LLC $1,284,610 50,635 0.16% Shares
ALLIANCEBERNSTEIN L.P. $1,145,662 50,693 0.15% Shares
Integrated Wealth Concepts LLC $1,110,299 43,764 0.14% Shares
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO $1,049,937 41,385 0.13% Shares
INTECH INVESTMENT MANAGEMENT LLC $1,047,553 41,291 0.13% Shares
XTX Topco Ltd $1,028,119 40,525 0.13% Shares
Vinva Investment Management Ltd $1,005,956 27,587 0.13% Shares
VIRGINIA RETIREMENT SYSTEMS ET Al $987,322 38,150 0.13% Shares
FIFTH THIRD BANCORP $972,914 38,349 0.12% Shares
VOYA INVESTMENT MANAGEMENT LLC $964,517 38,018 0.12% Shares
LAZARD ASSET MANAGEMENT LLC $943,206 37,178 0.12% Shares
Steward Partners Investment Advisory, LLC $920,246 36,273 0.12% Shares
SEGALL BRYANT & HAMILL, LLC $885,210 34,892 0.11% Shares
NATIXIS $862,580 34,000 0.11% Shares
CITIGROUP INC $845,379 33,322 0.11% Shares
Legato Capital Management LLC $778,047 30,668 0.10% Shares
HSBC HOLDINGS PLC $747,369 29,482 0.09% Shares
LPL Financial LLC $723,654 28,524 0.09% Shares
Gotham Asset Management, LLC $716,525 28,243 0.09% Shares
Vident Advisory, LLC $683,544 26,943 0.09% Shares
VANGUARD ASSET MANAGEMENT, Ltd $671,037 26,450 0.09% Shares
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ $667,612 26,315 0.08% Shares
HighTower Advisors, LLC $616,948 24,318 0.08% Shares
RAYMOND JAMES FINANCIAL INC $609,514 24,025 0.08% Shares
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management $604,872 23,842 0.08% Shares
O'SHAUGHNESSY ASSET MANAGEMENT, LLC $587,392 23,153 0.07% Shares
MetLife Investment Management, LLC $586,250 23,108 0.07% Shares
Quantinno Capital Management LP $568,948 22,426 0.07% Shares
J. Goldman & Co LP $560,119 22,078 0.07% Shares
GREENWOOD CAPITAL ASSOCIATES LLC $552,965 21,796 0.07% Shares
VARCOV Co. $549,260 21,650 0.07% Shares
Illinois Municipal Retirement Fund $545,633 21,507 0.07% Shares
Aquatic Capital Management LLC $544,161 21,449 0.07% Shares
JANUS HENDERSON GROUP PLC $526,776 23,319 0.07% Shares

Company insiders 44 insiders · 17 officers · 15 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
David M Stack CEO and Chairman June 14, 2023 A 186,481 0 0 $0
Max Reinhardt President, Rest of World June 7, 2023 S 29,225 0 0 $0
James S Scibetta President June 5, 2017 S 25,118 0 0 $0
Scott Braunstein Chief Operating Officer Jan. 3, 2018 A 20,982 0 0 $0
Jonathan Slonin Chief Medical Officer Aug. 17, 2026 S 216,384 0 1 $-70,619
Lauren Riker Senior Vice President, Finance June 11, 2026 S 62,284 0 1 $-143,702
Kristen Williams Chief Administrative Officer June 3, 2026 F 167,062 0 1 $-228,468
Ronald J. Ellis Jr. Chief Strategy Officer June 7, 2023 S 30,909 0 0 $0
Dennis Mcloughlin Chief Customer Officer June 7, 2023 S 38,115 0 0 $0
Anthony Molloy Chief Lgl & Compliance Officer June 6, 2023 S 12,877 0 0 $0
Charles Anthony Laranjeira Chief Technical Officer June 14, 2022 M 41,752 0 0 $0
Richard Scranton Chief Scientific Officer Nov. 8, 2019 M 16,061 0 0 $0
Robert J. Weiland Chief Commercial Officer June 4, 2018 S 5,088 0 0 $0
James B Jones SVP & Chief Medical Officer Nov. 20, 2017 S 16,823 0 0 $0
Taunia Markvicka SVP, Chief Commercial Officer March 17, 2015 M 8,579 0 0 $0
Gary Patou Chief Medical Officer Aug. 7, 2014 M 0 0 0 $0
John Pratt General Manager, San Diego June 13, 2013 M 0 0 0 $0
Marcelo Bigal Director June 10, 2026 A 17,798 0 0 $0
Alethia Young Director June 10, 2026 A 17,798 0 0 $0
Christopher Christie Director June 10, 2026 A 23,059 0 0 $0
Samit Hirawat Director June 10, 2026 A 6,405 0 0 $0
Mark Froimson Director June 10, 2026 A 26,541 0 0 $0
Michael J. Yang Director June 10, 2026 A 19,798 0 0 $0
Laura Brege Director June 10, 2026 A 30,120 0 0 $0
Thomas G Wiggans Director June 10, 2026 A 0 0 $0
Yvonne Greenstreet Director June 8, 2022 A 13,247 0 0 $0
John P Longenecker PHD Director March 3, 2022 M 18,823 0 0 $0
Andreas Wicki Director March 15, 2021 S 451,324 0 0 $0
Dennis L Winger Director June 14, 2017 A 7,490 0 0 $0
Fred A Middleton Director June 24, 2013 S 0 0 0 $0
Luke Evnin Director June 12, 2013 A 0 0 0 $0
HBM Healthcare Investments (Cayman) Ltd. 10% owner March 25, 2013 S 2,233,993 0 0 $0
Abraham Ceesay Sept. 4, 2025 S 9,039 0 1 $-64,005
Mark A. Kronenfeld June 11, 2025 A 34,901 0 0 $0
Brendan Teehan Feb. 4, 2025 A 54,000 0 0 $0
Frank D. Lee Feb. 1, 2025 A 448,409 0 0 $0
Daryl Gaugler Dec. 31, 2024 A 115,443 0 0 $0
Shawn Cross Nov. 4, 2024 A 75,000 0 0 $0
Charles A. Reinhart III June 12, 2024 A 51,867 0 0 $0
Paul J Hastings June 12, 2024 A 12,724 0 0 $0
Gary W Pace March 8, 2024 S 22,127 0 0 $0
Roy Winston Aug. 2, 2023 S 52,440 0 0 $0
Donald C. Manning June 9, 2021 A 29,520 0 0 $0
GORDON CARL L Feb. 8, 2011 C 2,828,941 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 16 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
DOMA PERPETUAL CAPITAL MANAGEMENT LLC, DOMA1 LLC, DOMA Perpetual LO Equity Master Fund LP, DOMA Perpetual Partners GP LLC, Pedro Escudero, The John Templeton Foundation, DOMA2 LLC, Eric de Armas ×4 filings March 12, 2026 7.30% Amendment Board campaign SEC
Consonance Capital Management LP, Consonance Capman GP LLC, Mitchell Blutt ×5 filings Sept. 6, 2019 Initial filing SEC
Undisclosed reporting person March 18, 2014 Initial filing SEC
Undisclosed reporting person July 26, 2013 Initial filing SEC
Undisclosed reporting person April 2, 2013 Initial filing SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person March 21, 2013 Initial filing SEC
Sanderling Venture Partners VI, L.P., Sanderling Ventures Management VI, Sanderling VI Beteiligungs GmbH & Co. KG, Sanderling VI Limited Partnership, Sanderling Venture Partners VI Co-Investment Fund, L.P., Middleton, McNeil, Mills & Associates VI, LLC, Fred A. Middleton ×4 filings March 21, 2013 Initial filing Passive investment SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Sept. 28, 2012 Initial filing SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person June 15, 2012 Initial filing SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person March 19, 2012 Initial filing SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Dec. 1, 2011 Initial filing SEC
Undisclosed reporting person Dec. 1, 2011 Initial filing Passive investment SEC
MPM BioVentures IV-QP, L.P., MPM BioVentures IV GmbH & Co. Beteiligungs KG, MPM Asset Management Investors BV4 LLC, MPM BioVentures IV GP LLC, MPM BioVentures IV LLC, Ansbert Gadicke, Luke Evnin, Steven St. Peter, Todd Foley, James Paul Scopa, Vaughn M. Kailian, John Vander Vort Nov. 29, 2011 Initial filing Passive investment SEC
Undisclosed reporting person, Undisclosed reporting person, Undisclosed reporting person Feb. 18, 2011 Initial filing SEC
Undisclosed reporting person Feb. 18, 2011 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 80 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
PILL · Direxion Shares ETF Trust 1.49% 7,557 NS April 30, 2026 N-PORT
RNIN · EA Series Trust 1.29% 77,493 NS April 30, 2026 N-PORT
SIXS · EXCHANGE TRADED CONCEPTS TRUST 1.15% 62,939 NS May 31, 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0.53% 4,821 SH Aug. 8, 2026 Daily
CAFG · Pacer Funds Trust 0.53% 4,674 NS April 30, 2026 N-PORT
PSCH · Invesco Exchange-Traded Fund Trust … 0.50% 34,147 SH Aug. 8, 2026 Daily
BRNY · EA Series Trust 0.49% 105,237 NS April 30, 2026 N-PORT
RZG · Invesco Exchange-Traded Fund Trust 0.44% 24,539 SH Aug. 8, 2026 Daily
SIXL · EXCHANGE TRADED CONCEPTS TRUST 0.44% 35,685 NS May 31, 2026 N-PORT
SCOW · Pacer Funds Trust 0.25% 151 NS April 30, 2026 N-PORT
IHE · iShares Trust 0.22% 140,292 SH Aug. 8, 2026 Daily
XSHQ · Invesco Exchange-Traded Fund Trust … 0.21% 26,878 SH Aug. 8, 2026 Daily
CALF · Pacer Funds Trust 0.17% 228,340 NS April 30, 2026 N-PORT
JPSE · J.P. Morgan Exchange-Traded Fund Tr… 0.16% 37,351 NS April 30, 2026 N-PORT
VFVA · VANGUARD WELLINGTON FUND 0.13% 42,794 SH Aug. 8, 2026 Daily
AFSM · First Trust Exchange-Traded Fund VI… 0.12% 5,078 NS May 31, 2026 N-PORT
IJT · iShares Trust 0.11% 366,482 SH Aug. 8, 2026 Daily
GSSC · Goldman Sachs ETF Trust 0.11% 46,867 NS May 31, 2026 N-PORT
VFMF · VANGUARD WELLINGTON FUND 0.11% 30,919 SH Aug. 8, 2026 Daily
VIOG · VANGUARD ADMIRAL FUNDS 0.11% 46,835 SH Aug. 8, 2026 Daily
FSMD · FIDELITY COVINGTON TRUST 0.11% 101,562 NS April 30, 2026 N-PORT
SMMV · iShares Trust 0.11% 12,284 SH Aug. 8, 2026 Daily
PRFZ · Invesco Exchange-Traded Fund Trust 0.08% 91,266 SH Aug. 8, 2026 Daily
DFSV · Dimensional ETF Trust 0.08% 228,455 NS April 30, 2026 N-PORT
IBBQ · Invesco Exchange-Traded Fund Trust … 0.07% 2,141 SH Aug. 8, 2026 Daily
AVUV · AMERICAN CENTURY ETF TRUST 0.07% 762,506 NS May 31, 2026 N-PORT
QVMS · Invesco Exchange-Traded Fund Trust … 0.06% 6,504 SH Aug. 8, 2026 Daily
XJR · iShares Trust 0.06% 4,673 SH Aug. 8, 2026 Daily
SMDX · Tidal Trust III 0.06% 3,111 NS April 30, 2026 N-PORT
VTWV · VANGUARD SCOTTSDALE FUNDS 0.06% 31,734 SH Aug. 8, 2026 Daily
IWN · iShares Trust 0.06% 336,803 SH Aug. 8, 2026 Daily
AVSC · AMERICAN CENTURY ETF TRUST 0.06% 70,645 NS May 31, 2026 N-PORT
IJR · iShares Trust 0.06% 2,401,037 SH Aug. 8, 2026 Daily
ROSC · Lattice Strategies Trust 0.05% 1,091 NS April 30, 2026 N-PORT
VIOO · VANGUARD ADMIRAL FUNDS 0.05% 137,158 SH Aug. 8, 2026 Daily
RWJ · Invesco Exchange-Traded Fund Trust … 0.05% 40,427 SH Aug. 8, 2026 Daily
BIB · ProShares Trust 0.05% 1,495 NS May 31, 2026 N-PORT
SAA · ProShares Trust 0.04% 492 NS May 31, 2026 N-PORT
FNDA · SCHWAB STRATEGIC TRUST 0.04% 161,376 NS May 31, 2026 N-PORT
VFQY · VANGUARD WELLINGTON FUND 0.04% 7,883 SH Aug. 8, 2026 Daily
IWM · iShares Trust 0.03% 1,012,844 SH Aug. 8, 2026 Daily
RSSL · Global X Funds 0.03% 17,676 NS April 30, 2026 N-PORT
VTWO · VANGUARD SCOTTSDALE FUNDS 0.03% 228,207 SH Aug. 8, 2026 Daily
ISCV · iShares Trust 0.03% 8,216 SH Aug. 8, 2026 Daily
DFAT · Dimensional ETF Trust 0.03% 159,088 NS April 30, 2026 N-PORT
PKW · Invesco Exchange-Traded Fund Trust 0.03% 20,231 SH Aug. 8, 2026 Daily
EBIT · Harbor ETF Trust 0.02% 109 NS April 30, 2026 N-PORT
DFAS · Dimensional ETF Trust 0.02% 131,931 NS April 30, 2026 N-PORT
ITWO · ProShares Trust 0.02% 1,922 NS May 31, 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0.02% 200,073 NS May 31, 2026 N-PORT