Insider at

04

Insider transactions

05
0 buys (P) 0 sells (S) Net: $0 + 17 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

No open-market trades on record; showing all filings.

DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
June 18, 2026 PEPG A 34,000 · · 34,000 Direct · Acquired (price as of 2026-10-05)
June 9, 2026 RLAY A 32,947 · · 32,947 Direct · Acquired (price as of 2026-10-05)
April 16, 2026 TYRA A 44,400 · · 44,400 Direct · Acquired (price as of 2026-10-05)
Feb. 5, 2026 SGP A 27,400 · · 27,400 Direct · Acquired (price as of 2026-10-05)
Nov. 4, 2025 RLAY A 207,931 · · 207,931 Direct · Acquired (price as of 2026-10-05)
June 4, 2025 PEPG A 16,000 · · 16,000 Direct · Acquired (price as of 2026-10-05)
June 20, 2024 PEPG A 13,000 · · 13,000 Direct · Acquired (price as of 2026-10-05)
June 5, 2024 JBIO A 12,500 · · 12,500 Direct · Acquired (price as of 2026-10-05)
March 4, 2024 JBIO A 1,531 $16.37 $25,062 1,531 Direct · Acquired -97.5% (price as of 2026-10-05)
Jan. 2, 2024 JBIO A 2,964 $13.49 $39,984 2,964 Direct · Acquired -97.0% (price as of 2026-10-05)
July 10, 2023 JBIO A 25,000 · · 25,000 Direct · Acquired (price as of 2026-10-05)
June 22, 2023 PEPG A 9,000 · · 9,000 Direct · Acquired (price as of 2026-10-05)
Oct. 3, 2022 PEPG A 22,686 · · 22,686 Direct · Acquired (price as of 2026-10-05)
June 22, 2020 TPST A 12,000 · · 12,000 Direct · Acquired (price as of 2026-10-05)
June 20, 2019 TPST A 12,000 · · 12,000 Direct · Acquired (price as of 2026-10-05)
Jan. 15, 2019 TPST A 6,000 · · 6,000 Direct · Acquired (price as of 2026-10-05)
Dec. 7, 2018 TPST A 14,880 · · 14,880 Direct · Acquired (price as of 2026-10-05)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

06
DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
June 18, 2026 PEPG Stock Option (Right to Buy) Common Stock (34,000) $1.79 June 17, 2036 34,000 Acquired
June 9, 2026 RLAY Stock Option (Right to Buy) Common Stock (32,947) $14.09 June 8, 2036 32,947 Acquired
April 16, 2026 TYRA Stock Option (Right to Buy) Common (44,400) $35.12 April 15, 2036 44,400 Acquired
Feb. 5, 2026 SGP Stock Option (right to buy) Common Stock (27,400) $16.00 Feb. 5, 2036 27,400 Acquired
Nov. 4, 2025 RLAY Stock Option (Right to Buy) Common Stock (207,931) $6.86 Nov. 3, 2035 207,931 Acquired
June 4, 2025 PEPG Stock Option (Right to Buy) Common Stock (16,000) $1.51 June 3, 2035 16,000 Acquired
June 20, 2024 PEPG Stock Option (Right to Buy) Common Stock (13,000) $16.80 June 19, 2034 13,000 Acquired
June 5, 2024 JBIO Stock Option (Right to Buy) Common Stock (12,500) $18.90 June 4, 2034 12,500 Acquired
March 4, 2024 JBIO Stock Option (Right to Buy) Common Stock (1,531) $22.49 March 4, 2034 1,531 Acquired
Jan. 2, 2024 JBIO Stock Option (Right to Buy) Common Stock (2,964) $21.81 Jan. 1, 2034 2,964 Acquired
July 10, 2023 JBIO Stock Option (Right to Buy) Common Stock (25,000) $18.08 July 9, 2033 25,000 Acquired
June 22, 2023 PEPG Stock Option (Right to Buy) Common Stock (9,000) $9.61 June 21, 2033 9,000 Acquired
Oct. 3, 2022 PEPG Stock Option (Right to Buy) Common Stock (22,686) $9.31 Oct. 2, 2032 22,686 Acquired
June 22, 2020 TPST Stock Option (right to buy) Common Stock (12,000) $2.40 June 21, 2030 12,000 Acquired
June 20, 2019 TPST Stock Option (right to buy) Common Stock (12,000) $11.59 June 19, 2029 12,000 Acquired
Jan. 15, 2019 TPST Stock Option (right to buy) Common Stock (6,000) $8.80 Jan. 14, 2029 6,000 Acquired
Dec. 7, 2018 TPST Stock Option (right to buy) Common Stock (14,880) $16.40 Sept. 20, 2028 14,880 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 1 holding

07

Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
April 20, 2026 TYRA No securities are beneficially owned. 0 Direct