Jack Kaye

Insider

First SEC filing: June 5, 2026 · Latest: June 5, 2026

On this page

Insider at Companies where this person is a reporting insider.
Insider transactions Every share this person bought or sold, from Form 4 filings.
Derivatives Options and other derivative holdings reported by this person.
Initial holdings The stakes this person held when they first started reporting.

Insider at

Insider transactions

0 buys (P) 9 sells (S) Net: $-2,693,581 + 40 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

40 other filings hidden

Date	Ticker	Code	Shares	Price	Value	Owned after	Δ own	A/D	vs now
June 30, 2026	QURE	M 10b5-1	17,060	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-20)
June 30, 2026	QURE	M 10b5-1	4,107	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-20)
June 30, 2026	QURE	S 10b5-1	17,060	$46.43	$792,096	25,996 Direct	-39.62%	Disposed	3.2% (price as of 2026-08-20)
June 30, 2026	QURE	M 10b5-1	17,060	$20.18	$344,271	43,056 Direct	+65.63%	Acquired	137.4% (price as of 2026-08-20)
June 30, 2026	QURE	S 10b5-1	4,107	$46.49	$190,934	25,996 Direct	-13.64%	Disposed	3.0% (price as of 2026-08-20)
June 30, 2026	QURE	M 10b5-1	4,107	$37.00	$151,959	30,103 Direct	+15.80%	Acquired	29.5% (price as of 2026-08-20)
June 17, 2026	QURE	M 10b5-1	5,295	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-20)
June 17, 2026	QURE	S 10b5-1	5,295	$42.57	$225,408	25,996 Direct	-16.92%	Disposed	12.5% (price as of 2026-08-20)
June 17, 2026	QURE	M 10b5-1	5,295	$31.71	$167,904	31,291 Direct	+20.37%	Acquired	51.1% (price as of 2026-08-20)
June 11, 2026	QURE	S	1,993	$27.06	$53,931	25,996 Direct	-7.12%	Disposed	77.0% (price as of 2026-08-20)
June 10, 2026	QURE	A	13,980	—	—	13,980 Direct	—	Acquired	(price as of 2026-08-20)
June 10, 2026	QURE	A	7,550	—	—	27,989 Direct	+36.94%	Acquired	(price as of 2026-08-20)
June 3, 2026	QURE	M 10b5-1	2,645	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-20)
June 3, 2026	QURE	S 10b5-1	2,645	$30.01	$79,376	20,439 Direct	-11.46%	Disposed	59.6% (price as of 2026-08-20)
June 3, 2026	QURE	M 10b5-1	2,645	$16.04	$42,426	23,084 Direct	+12.94%	Acquired	198.6% (price as of 2026-08-20)
Jan. 9, 2026	QURE	M 10b5-1	6,390	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-20)
Jan. 9, 2026	QURE	S 10b5-1	6,390	$27.28	$174,319	20,439 Direct	-23.82%	Disposed	75.6% (price as of 2026-08-20)
Jan. 9, 2026	QURE	M 10b5-1	6,390	$19.39	$123,902	26,829 Direct	+31.26%	Acquired	147.0% (price as of 2026-08-20)
Nov. 4, 2025	QURE	M 10b5-1	17,810	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-20)
Nov. 4, 2025	QURE	M 10b5-1	11,000	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-20)
Nov. 4, 2025	QURE	M 10b5-1	10,000	—	—	0 Direct	-100.00%	Disposed	(price as of 2026-08-20)
Nov. 4, 2025	QURE	S 10b5-1	17,810	$30.33	$540,177	20,439 Direct	-46.56%	Disposed	57.9% (price as of 2026-08-20)
Nov. 4, 2025	QURE	M 10b5-1	17,810	$14.08	$250,765	38,249 Direct	+87.14%	Acquired	240.2% (price as of 2026-08-20)
Nov. 4, 2025	QURE	S 10b5-1	11,000	$30.34	$333,740	20,439 Direct	-34.99%	Disposed	57.9% (price as of 2026-08-20)
Nov. 4, 2025	QURE	M 10b5-1	11,000	$5.37	$59,070	31,439 Direct	+53.82%	Acquired	792.0% (price as of 2026-08-20)
Nov. 4, 2025	QURE	S 10b5-1	10,000	$30.36	$303,600	20,439 Direct	-32.85%	Disposed	57.8% (price as of 2026-08-20)
Nov. 4, 2025	QURE	M 10b5-1	10,000	$7.37	$73,700	30,439 Direct	+48.93%	Acquired	549.9% (price as of 2026-08-20)
June 20, 2025	QURE	S	2,112	$14.45	$30,518	20,439 Direct	-9.37%	Disposed	231.5% (price as of 2026-08-20)
June 11, 2025	QURE	A	15,630	—	—	15,630 Direct	—	Acquired	(price as of 2026-08-20)
June 11, 2025	QURE	A	7,970	—	—	22,551 Direct	+54.66%	Acquired	(price as of 2026-08-20)
June 19, 2024	QURE	A	15,840	—	—	15,840 Direct	—	Acquired	(price as of 2026-08-20)
June 19, 2024	QURE	A	8,080	—	—	14,581 Direct	+124.29%	Acquired	(price as of 2026-08-20)
June 13, 2024	QURE	S	2,218	$5.16	$11,445	6,501 Direct	-25.44%	Disposed	828.3% (price as of 2026-08-20)
June 16, 2023	QURE	S	2,280	$18.93	$43,160	34,119 Direct	-6.26%	Disposed	153.0% (price as of 2026-08-20)
June 13, 2023	QURE	A	17,060	—	—	17,060 Direct	—	Acquired	(price as of 2026-08-20)
June 13, 2023	QURE	A	8,700	—	—	36,399 Direct	+31.41%	Acquired	(price as of 2026-08-20)
Feb. 27, 2023	QURE	S	384	$19.99	$7,676	27,699 Direct	-1.37%	Disposed	139.6% (price as of 2026-08-20)
June 15, 2022	QURE	A	17,810	—	—	17,810 Direct	—	Acquired	(price as of 2026-08-20)
June 15, 2022	QURE	A	9,080	—	—	28,083 Direct	+47.78%	Acquired	(price as of 2026-08-20)
Feb. 28, 2022	QURE	S	600	$16.76	$10,056	19,003 Direct	-3.06%	Disposed	185.8% (price as of 2026-08-20)
Feb. 24, 2022	QURE	A	2,645	—	—	2,645 Direct	—	Acquired	(price as of 2026-08-20)
Feb. 24, 2022	QURE	A	1,534	—	—	19,603 Direct	+8.49%	Acquired	(price as of 2026-08-20)
March 2, 2021	QURE	S	504	$37.60	$18,950	18,069 Direct	-2.71%	Disposed	27.4% (price as of 2026-08-20)
Feb. 25, 2021	QURE	A	4,107	—	—	4,107 Direct	—	Acquired	(price as of 2026-08-20)
Feb. 25, 2021	QURE	A	2,382	—	—	18,573 Direct	+14.71%	Acquired	(price as of 2026-08-20)
Feb. 27, 2020	QURE	A	3,620	—	—	3,620 Direct	—	Acquired	(price as of 2026-08-20)
Feb. 27, 2020	QURE	A	2,063	—	—	16,191 Direct	+14.60%	Acquired	(price as of 2026-08-20)
Jan. 28, 2020	QURE	S	806	$62.20	$50,133	14,128 Direct	-5.40%	Disposed	-23.0% (price as of 2026-08-20)
Jan. 2, 2020	DYAI	A	75,000	—	—	75,000 Direct	—	Acquired	(price as of 2026-08-20)
June 25, 2019	DYAI	A	25,000	—	—	25,000 Direct	—	Acquired	(price as of 2026-08-20)
Jan. 28, 2019	QURE	S	1,210	$31.31	$37,885	14,934 Direct	-7.50%	Disposed	53.0% (price as of 2026-08-20)
Jan. 25, 2019	QURE	A	5,295	—	—	5,295 Direct	—	Acquired	(price as of 2026-08-20)
Jan. 25, 2019	QURE	A	3,230	—	—	16,144 Direct	+25.01%	Acquired	(price as of 2026-08-20)
Jan. 29, 2018	QURE	S	2,878	$18.53	$53,329	12,914 Direct	-18.22%	Disposed	158.5% (price as of 2026-08-20)
Jan. 26, 2018	QURE	A	6,390	—	—	6,390 Direct	—	Acquired	(price as of 2026-08-20)
Jan. 26, 2018	QURE	A	4,792	—	—	15,792 Direct	+43.56%	Acquired	(price as of 2026-08-20)
Jan. 27, 2017	QURE	A	11,000	—	—	11,000 Direct	—	Acquired	(price as of 2026-08-20)
Jan. 27, 2017	QURE	A	11,000	—	—	11,000 Direct	—	Acquired	(price as of 2026-08-20)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II)

Options, RSUs and convertible securities reported on Form 4 Table II.

Date	Ticker	Security	Underlying	Exercise price	Expiration	Shares	A/D
June 30, 2026	QURE	Stock Option (Right to Buy)	Ordinary Shares (17,060)	$20.18	June 13, 2033	17,060	Disposed
June 30, 2026	QURE	Stock Option (Right to Buy)	Ordinary Shares (4,107)	$37.00	Feb. 25, 2031	4,107	Disposed
June 17, 2026	QURE	Stock Option (Right to Buy)	Ordinary Shares (5,295)	$31.71	Jan. 25, 2029	5,295	Disposed
June 10, 2026	QURE	Stock Option (Right to Buy)	Ordinary Shares (13,980)	$26.82	June 10, 2036	13,980	Acquired
June 3, 2026	QURE	Stock Option (Right to Buy)	Ordinary Shares (2,645)	$16.04	Feb. 24, 2032	2,645	Disposed
Jan. 9, 2026	QURE	Stock Option (Right to Buy)	Ordinary Shares (6,390)	$19.39	Jan. 26, 2028	6,390	Disposed
Nov. 4, 2025	QURE	Stock Option (Right to Buy)	Ordinary Shares (17,810)	$14.08	June 15, 2032	17,810	Disposed
Nov. 4, 2025	QURE	Stock Option (Right to Buy)	Ordinary Shares (11,000)	$5.37	Jan. 27, 2027	11,000	Disposed
Nov. 4, 2025	QURE	Stock Option (Right to Buy)	Ordinary Shares (10,000)	$7.37	June 29, 2027	10,000	Disposed
June 11, 2025	QURE	Stock Option (Right to Buy)	Ordinary Shares (15,630)	$16.22	June 11, 2035	15,630	Acquired
June 19, 2024	QURE	Stock Option (Right to Buy)	Ordinary Shares (15,840)	$4.57	June 19, 2034	15,840	Acquired
June 13, 2023	QURE	Stock Option (Right to Buy)	Ordinary Shares (17,060)	$20.18	June 13, 2033	17,060	Acquired
June 15, 2022	QURE	Stock Option (Right to Buy)	Ordinary Shares (17,810)	$14.08	June 15, 2032	17,810	Acquired
Feb. 24, 2022	QURE	Stock Option (Right to Buy)	Ordinary Shares (2,645)	$16.04	Feb. 24, 2032	2,645	Acquired
Feb. 25, 2021	QURE	Stock Option (Right to Buy)	Ordinary Shares (4,107)	$37.00	Feb. 25, 2031	4,107	Acquired
Feb. 27, 2020	QURE	Stock Option (Right to Buy)	Ordinary Shares (3,620)	$51.81	Feb. 27, 2030	3,620	Acquired
Jan. 2, 2020	DYAI	Stock Option	Common Stock (75,000)	$5.27	Jan. 1, 2030	75,000	Acquired
June 25, 2019	DYAI	Stock Option	Common Stock (25,000)	$5.83	June 24, 2029	25,000	Acquired
Jan. 25, 2019	QURE	Stock Option (Right to Buy)	Ordinary Shares (5,295)	$31.71	Jan. 25, 2029	5,295	Acquired
Jan. 26, 2018	QURE	Stock Option (Right to Buy)	Ordinary Shares (6,390)	$19.39	Jan. 26, 2028	6,390	Acquired
Jan. 27, 2017	QURE	Restricted Stock Units	Ordinary Shares (11,000)	$0.00	—	11,000	Acquired
Jan. 27, 2017	QURE	Stock Option (Right to Buy)	Ordinary Shares (11,000)	$5.37	Jan. 27, 2027	11,000	Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 29 holdings

Securities held when first becoming an insider, per SEC Form 3.

Date	Ticker	Security	Shares	Ownership
Feb. 13, 2019	DYAI	Common Stock	72,707	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (18,750)	18,750	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (14,062)	14,062	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (14,062)	14,062	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (14,062)	14,062	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (14,062)	14,062	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (12,500)	12,500	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (9,375)	9,375	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (9,375)	9,375	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (9,375)	9,375	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (9,375)	9,375	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (12,500)	12,500	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (9,375)	9,375	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (9,375)	9,375	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (9,375)	9,375	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (9,375)	9,375	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (7,500)	7,500	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (22,500)	22,500	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (6,250)	6,250	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (4,688)	4,688	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (4,687)	4,687	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (4,688)	4,688	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (4,687)	4,687	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (6,250)	6,250	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (4,688)	4,688	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (4,687)	4,687	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (4,688)	4,688	Direct
Feb. 13, 2019	DYAI	Stock Option→ Common Stock (4,687)	4,687	Direct
Jan. 10, 2017	QURE	Stock Option (right to buy)→ Ordinary Shares (10,000)	10,000	Direct