QURE uniQure N.V. - Ordinary Shares

NASDAQ · Biotechnology · View on SEC EDGAR ↗
$25.71
Price · May 20, 2026
Fundamentals as of May 5, 2026

QURE Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$25.71
Market Cap
$1.49B
P/E (TTM)
-6.9
EPS (TTM)
$-3.46
Revenue (TTM)
$16M
Div Yield
ROE
-204.2%
Debt/Equity
0.2
52W Range
$9 – $72

QURE Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income $16M
10-point trend, -35.9%
2016-12-31 2025-12-31
EPS $-3.46
7-point trend, -11.3%
2019-12-31 2025-12-31
Free Cash Flow $-178M
9-point trend, -103.9%
2016-12-31 2025-12-31
Margins -1236.0%

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
QURE
Peer Median
P/E (TTM)
5-point trend, -334.8%
-6.9
P/S (TTM)
5-point trend, +4956.7%
92.7
92.4
P/B
5-point trend, +365.3%
7.5
5.8
EV / EBITDA
5-point trend, -585.0%
-7.9
Price / FCF
5-point trend, -335.6%
-8.4

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
QURE
Peer Median
Operating Margin
5-point trend, -2042.3%
-1151.4%
Net Profit Margin
5-point trend, -2065.0%
-1236.0%
-905.7%
ROA
5-point trend, -150.2%
-28.8%
-27.1%
ROE
5-point trend, -467.5%
-204.2%
-58.4%
ROIC
5-point trend, -273.8%
-76.7%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
QURE
Peer Median
Debt / Equity
5-point trend, +47.4%
0.2
28.9
Current Ratio
5-point trend, -39.0%
10.4
7.9
Quick Ratio
5-point trend, -91.6%
1.3

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
QURE
Peer Median
Revenue YoY
5-point trend, -96.9%
-40.6%
Revenue CAGR 3Y
5-point trend, -96.9%
-46.7%
Revenue CAGR 5Y
5-point trend, -96.9%
-15.6%

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
QURE
Peer Median
EPS (Diluted)
5-point trend, -149.1%
$-3.46

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
QURE
Peer Median

QURE Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 21 analysts
  • Strong Buy 6 28.6%
  • Buy 10 47.6%
  • Hold 5 23.8%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

11 analysts · 2026-05-16
Median target $34.78 +35.3%
Mean target $39.15 +52.3%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.07%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.85 $-0.89 0.04%
Dec. 31, 2025 $-0.64 $-0.97 0.33%
Sept. 30, 2025 $-1.38 $-0.92 -0.46%
June 30, 2025 $-0.69 $-0.91 0.22%
March 31, 2025 $-0.82 $-1.03 0.21%

Peer Comparison Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
QURE $1.49B -6.9 -40.6% -1236.0% -204.2%
NAMS
PRQR

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 17
Annual Income Statement data for QURE
Metric Trend 20252024202320222021202020192018201720162015
Revenue 11-point trend, +52.2% $16M $27M $16M $106M $524M $38M $7M $11M $13M $25M $11M
Cost of Revenue 10-point trend, +25.1% $2M $1M $65.0K $1M $25M $3M $2M $1M $817.0K $1M ·
R&D Expense 11-point trend, +137.9% $141M $144M $215M $198M $144M $122M $95M $75M $72M $73M $59M
SG&A Expense 11-point trend, +179.9% $65M $53M $75M $55M $56M $43M $34M $25M $25M $26M $23M
Operating Expenses 11-point trend, +151.9% $208M $215M $303M $256M $225M $165M $128M $100M $97M $99M $83M
Operating Income 11-point trend, -160.5% $-185M $-184M $-283M $-143M $311M $-125M $-121M $-88M $-71M $-72M $-71M
Interest Expense 9-point trend, +1515.7% · · $42M $12M $7M $4M $4M $2M $2M $2M $3M
Interest Income 11-point trend, +13922.3% $17M $21M $20M $609.0K $162.0K $938.0K $4M $3M $117.0K $70.0K $121.0K
Other Non-op 9-point trend, +252.2% $11M · · $3M $-160.0K $483.0K $-3M $208.0K $-2M $785.0K $-7M
Pretax Income 11-point trend, -132.2% $-193M $-237M $-307M $-128M $333M $-141M $-124M $-83M $-79M $-72M $-83M
Income Tax 10-point trend, +577.6% $6M $2M $2M $-1M $3M $-16M · $231.0K $-199.0K $1M $-1M
Net Income 11-point trend, -142.4% $-199M $-240M $-308M $-127M $330M $-125M $-124M $-83M $-79M $-73M $-82M
EPS (Basic) 7-point trend, -11.3% $-3.46 $-4.92 $-6.47 $-2.71 $7.17 $-2.81 $-3.11 · · · ·
EPS (Diluted) 7-point trend, -11.3% $-3.46 $-4.92 $-6.47 $-2.71 $7.04 $-2.81 $-3.11 · · · ·
Shares (Basic) 7-point trend, +43.8% 57,502,068 48,649,129 47,670,986 46,735,045 45,986,467 44,466,365 39,999,450 · · · ·
Shares (Diluted) 7-point trend, +43.8% 57,502,068 48,649,129 47,670,986 46,735,045 46,840,972 44,466,365 39,999,450 · · · ·
EBITDA 9-point trend, -157.6% $-185M $-184M $-283M $-143M $311M $-125M $-121M · $-71M $-72M ·
Balance Sheet 29
Annual Balance Sheet data for QURE
Metric Trend 20252024202320222021202020192018201720162015
Cash & Equivalents 11-point trend, -63.8% $80M $159M $241M $228M $556M $245M $378M $235M $159M $132M $222M
Receivables 3-point trend, +59.3% $6M · · · · $7M · · · $4M ·
Inventory 3-point trend, +2436.7% · · $12M $7M · · · · · · $474.0K
Prepaid Expense 11-point trend, +2871.9% $21M $9M $15M $12M $11M $4M $5M $1M $1M $996.0K $690.0K
Other Current Assets 6-point trend, +153.3% · · · · · $3M $748.0K $329.0K $687.0K $1M $1M
Current Assets 11-point trend, +187.6% $656M $390M $652M $477M $628M $259M $384M $237M $163M $144M $228M
PP&E (Net) 11-point trend, -46.9% $14M $20M $47M $51M $44M $32M $29M $29M $34M $36M $26M
PP&E (Gross) 11-point trend, +55.7% $58M $52M $102M $95M $80M $68M $57M $52M $51M $48M $37M
Accum. Depreciation 11-point trend, +299.9% $44M $32M $56M $44M $37M $35M $29M $23M $17M $12M $11M
Goodwill 11-point trend, +5171.3% $25M $22M $26M $26M $28M $542.0K $496.0K $506.0K $530.0K $465.0K $481.0K
Intangibles 11-point trend, +968.1% $73M $71M $60M $59M $63M $3M $5M $5M $10M $8M $7M
Other Non-current Assets 9-point trend, +347.4% $6M $1M $3M $6M $6M $3M · · $2M $2M $1M
Total Assets 11-point trend, +214.1% $825M $557M $832M $705M $809M $340M $449M $274M $210M $190M $263M
Accounts Payable 11-point trend, +27.4% $5M $7M $7M $11M $3M $4M $6M $4M $3M $6M $4M
Accrued Liabilities 8-point trend, +401.6% $41M $29M $31M $31M $28M $18M $12M $8M · · ·
Current Liabilities 11-point trend, +133.8% $63M $40M $74M $76M $37M $27M $32M $20M $19M $23M $27M
Capital Leases 7-point trend, -68.4% $10M $11M $28M $32M $29M $30M $31M · · · ·
Deferred Tax 5-point trend, -38.3% $8M $7M $8M $8M $13M · · · · · ·
Other Non-current Liabilities 11-point trend, +532.4% $4M $8M $4M $935.0K $4M $3M $534.0K $435.0K $614.0K $51.0K $578.0K
Total Liabilities 11-point trend, +364.6% $626M $563M $624M $229M $213M $96M $126M $94M $120M $127M $135M
Long-term Debt 11-point trend, +255.9% $72M $66M $148M $144M $136M $42M $47M $48M $24M $20M $20M
Total Debt 9-point trend, +145.6% $50M $51M $102M $103M $101M $36M $36M · $21M $20M ·
Common Stock 11-point trend, +139.2% $4M $3M $3M $3M $3M $3M $3M $2M $2M $2M $2M
Paid-in Capital 11-point trend, +247.1% $1.58B $1.17B $1.15B $1.11B $1.08B $1.02B $987M $720M $567M $465M $456M
Retained Earnings 11-point trend, -311.8% $-1.33B $-1.13B $-890M $-582M $-455M $-785M $-660M $-536M $-475M $-396M $-323M
AOCI 11-point trend, -752.7% $-58M $-53M $-54M $-58M $-29M $-10M $-7M $-7M $-4M $-7M $-7M
Stockholders' Equity 11-point trend, +55.5% $199M $-7M $208M $476M $596M $244M $323M $180M $89M $64M $128M
Liabilities + Equity 11-point trend, +214.1% $825M $557M $832M $705M $809M $340M $449M $274M $210M $190M $263M
Shares Outstanding 11-point trend, +156.2% 62,336,717 48,988,087 47,833,830 46,968,032 46,298,635 44,777,799 43,711,954 37,351,653 31,339,040 25,257,420 24,327,944
Cash Flow 16
Annual Cash Flow data for QURE
Metric Trend 20252024202320222021202020192018201720162015
D&A 9-point trend, +95.7% $15M $13M $12M $9M $7M $11M $7M $12M $8M · ·
Stock-based Comp 11-point trend, +52.2% $18M $22M $35M $34M $26M $22M $18M $11M $10M $6M $12M
Deferred Tax 10-point trend, +234.7% $2M $2M $2M $-1M $3M $-16M · $209.0K $-209.0K $1M $-1M
Restructuring · · $3M · · · · · · · ·
Operating Cash Flow 11-point trend, -2483.0% $-178M $-183M $-146M $-145M $288M $-135M $-99M $-76M $-64M $-72M $7M
CapEx 11-point trend, -94.2% $439.0K $3M $7M $18M $17M $7M $6M $2M $4M $15M $8M
Investing Cash Flow 11-point trend, -3909.2% $-322M $163M $-206M $-183M $-67M $-9M $-7M $-4M $-6M $-17M $-8M
Debt Issued 2-point trend, +333.6% · · · · $64M · · $15M · · ·
Net Debt Issued 2-point trend, -182.8% · $-53M · · $64M · · · · · ·
Stock Issued 7-point trend, +978.5% · · · · $31M $7M $6M $5M $4M $3M $3M
Net Stock Activity 5-point trend, +7.9% · · · · $3M $7M $6M · $4M $3M ·
Financing Cash Flow 11-point trend, +158.5% $415M $-59M $363M $1M $95M $7M $249M $158M $90M $2M $161M
Net Change in Cash 11-point trend, -150.0% $-79M $-84M $13M $-328M $312M $-133M $143M $75M $28M $-89M $157M
Taxes Paid 3-point trend, +62750.0% $8M $21.0K $12.0K · · · · · · · ·
Free Cash Flow 9-point trend, -103.9% $-178M $-186M $-153M $-163M $271M $-142M $-104M · $-69M $-87M ·
Levered FCF 6-point trend, -117.3% · · $-195M $-174M $263M $-145M · · $-71M $-90M ·
Profitability 7
Annual Profitability data for QURE
Metric Trend 20252024202320222021202020192018201720162015
Operating Margin 9-point trend, -301.7% -1151.4% -679.6% -1785.5% -134.4% 59.3% -334.3% -1663.8% · -544.3% -286.7% ·
Net Margin 8-point trend, -104.4% -1236.0% -883.4% -1947.1% -119.1% 62.9% -333.3% -1705.8% · -604.7% · ·
Pretax Margin 9-point trend, -317.3% -1201.0% -874.4% -1935.0% -120.4% 63.5% -377.0% -1705.8% · -606.2% -287.8% ·
EBITDA Margin 9-point trend, -301.7% -1151.4% -679.6% -1785.5% -134.4% 59.3% -334.3% -1663.8% · -544.3% -286.7% ·
ROA 8-point trend, +27.3% -28.8% -34.5% -40.2% -16.8% 57.3% -31.7% -34.4% · -39.6% · ·
ROE 8-point trend, -97.1% -204.2% -976.4% -129.5% -28.3% 55.6% -53.0% -36.9% · -103.6% · ·
ROIC 8-point trend, +12.0% -76.7% -417.7% -92.0% -24.4% 44.1% -39.7% · · -64.6% -87.2% ·
Liquidity & Solvency 5
Annual Liquidity & Solvency data for QURE
Metric Trend 20252024202320222021202020192018201720162015
Current Ratio 9-point trend, +64.6% 10.4 9.7 8.8 6.3 17.1 9.5 12.1 · 8.5 6.3 ·
Quick Ratio 9-point trend, -78.7% 1.3 4.0 3.3 3.0 15.1 9.2 11.9 · 8.3 6.0 ·
Debt / Equity 9-point trend, -21.4% 0.2 -7.6 0.5 0.2 0.2 0.1 0.1 · 0.2 0.3 ·
LT Debt / Equity 9-point trend, -19.0% 0.2 -7.6 0.5 0.2 0.2 0.1 0.1 · 0.2 0.3 ·
Interest Coverage 7-point trend, +79.5% · · -6.8 -12.2 41.6 -32.8 -31.8 · -32.0 -33.1 ·
Efficiency 3
Annual Efficiency data for QURE
Metric Trend 20252024202320222021202020192018201720162015
Asset Turnover 9-point trend, -79.0% 0.0 0.0 0.0 0.1 0.9 0.1 0.0 · 0.1 0.1 ·
Inventory Turnover 2-point trend, -98.0% · · 0.0 0.3 · · · · · · ·
Receivables Turnover 2-point trend, -46.6% · · · · · 7.3 · · · 13.6 ·
Per Share 5
Annual Per Share data for QURE
Metric Trend 20252024202320222021202020192018201720162015
Book Value / Share 9-point trend, +26.7% $3.19 $-0.14 $4.34 $10.13 $12.87 $5.45 $7.39 · $2.85 $2.52 ·
Revenue / Share 5-point trend, -97.5% $0.28 $0.56 $0.33 $2.28 $11.19 · · · · · ·
Cash Flow / Share 5-point trend, -150.3% $-3.09 $-3.76 $-3.06 $-3.10 $6.15 · · · · · ·
Cash / Share 9-point trend, -75.5% $1.29 $3.24 $5.05 $4.85 $12.01 $5.47 $8.64 · $5.09 $5.25 ·
EPS (TTM) 7-point trend, -11.3% $-3.46 $-4.92 $-6.47 $-2.71 $7.04 $-2.81 $-3.11 · · · ·
Growth Rates 3
Annual Growth Rates data for QURE
Metric Trend 20252024202320222021202020192018201720162015
Revenue YoY 5-point trend, -103.1% -40.6% 71.2% -85.1% -79.7% 1296.8% · · · · · ·
Revenue CAGR 3Y 3-point trend, -87.1% -46.7% -62.7% -25.0% · · · · · · · ·
Revenue CAGR 5Y -15.6% · · · · · · · · · ·
Valuation (TTM) 14
Annual Valuation (TTM) data for QURE
Metric Trend 20252024202320222021202020192018201720162015
Revenue TTM 10-point trend, -35.9% $16M $27M $16M $106M $524M $38M $7M $11M $13M $25M ·
Net Income TTM 10-point trend, -171.2% $-199M $-240M $-308M $-127M $330M $-125M $-124M $-83M $-79M $-73M ·
Market Cap 9-point trend, +954.7% $1.49B $865M $324M $1.06B $960M $1.62B $3.13B · $614M $141M ·
Enterprise Value 9-point trend, +4907.2% $1.46B $758M $184M $940M $505M $1.41B $2.79B · $475M $29M ·
P/E 7-point trend, +70.0% -6.9 -3.6 -1.0 -8.4 2.9 -12.9 -23.0 · · · ·
P/S 9-point trend, +1544.3% 92.7 31.9 20.4 10.0 1.8 43.1 430.2 · 46.8 5.6 ·
P/B 9-point trend, +237.4% 7.5 -128.1 1.6 2.2 1.6 6.6 9.7 · 6.9 2.2 ·
P / Tangible Book 5-point trend, +119.6% 14.8 · 2.7 2.7 1.9 6.7 · · · · ·
P / Cash Flow 9-point trend, -327.8% -8.4 -4.7 -2.2 -7.3 3.3 -12.0 -31.7 · -9.6 -2.0 ·
P / FCF 9-point trend, -417.1% -8.4 -4.6 -2.1 -6.5 3.5 -11.4 -30.0 · -8.9 -1.6 ·
EV / EBITDA 9-point trend, -1843.6% -7.9 -4.1 -0.7 -6.6 1.6 -11.2 -23.0 · -6.7 -0.4 ·
EV / FCF 9-point trend, -2355.2% -8.2 -4.1 -1.2 -5.8 1.9 -9.9 -26.7 · -6.9 -0.3 ·
EV / Revenue 9-point trend, +7706.6% 90.8 27.9 11.6 8.8 1.0 37.5 383.3 · 36.3 1.2 ·
Earnings Yield 7-point trend, -233.2% -14.5% -27.9% -95.6% -11.9% 33.9% -7.8% -4.3% · · · ·

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Revenue $16M$27M$16M$106M$524M
Operating Margin % -1151.4%-679.6%-1785.5%-134.4%59.3%
Net Income $-199M$-240M$-308M$-127M$330M
Diluted EPS $-3.46$-4.92$-6.47$-2.71$7.04
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Debt / Equity 0.2-7.60.50.20.2
Current Ratio 10.49.78.86.317.1
Quick Ratio 1.34.03.33.015.1
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-178M$-186M$-153M$-163M$271M

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