Jeffery A. Meckler

Activist

First SEC filing: Dec. 30, 2025 · Latest: Dec. 30, 2025

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Insider at Companies where this person is a reporting insider.
Insider transactions Every share this person bought or sold, from Form 4 filings.
Derivatives Options and other derivative holdings reported by this person.
Initial holdings The stakes this person held when they first started reporting.

Insider at

Insider transactions

0 buys (P) 0 sells (S) Net: $0 + 28 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

28 other filings hidden

Date	Ticker	Code	Shares	Price	Value	Owned after	Δ own	A/D	vs now
May 15, 2025	TVTX	A	6,500	—	—	87,500 Direct	+8.02%	Acquired	(price as of 2026-08-21)
May 15, 2025	TVTX	A	19,500	—	—	19,500 Direct	—	Acquired	(price as of 2026-08-21)
Sept. 30, 2024	TVTX	M	40,000	$10.48	$419,200	121,000 Direct	+49.38%	Acquired	520.0% (price as of 2026-08-21)
Sept. 30, 2024	TVTX	S 10b5-1	40,000	$14.06	$562,400	81,000 Direct	-33.06%	Disposed	362.2% (price as of 2026-08-21)
Sept. 30, 2024	TVTX	M	40,000	—	—	0 Direct	—	Acquired	(price as of 2026-08-21)
May 8, 2024	TVTX	A	6,500	—	—	81,000 Direct	+8.72%	Acquired	(price as of 2026-08-21)
May 8, 2024	TVTX	A	19,500	—	—	19,500 Direct	—	Acquired	(price as of 2026-08-21)
May 17, 2023	TVTX	A	13,500	—	—	13,500 Direct	—	Acquired	(price as of 2026-08-21)
May 17, 2023	TVTX	A	4,500	—	—	74,500 Direct	+6.43%	Acquired	(price as of 2026-08-21)
May 11, 2022	TVTX	A	9,000	—	—	9,000 Direct	—	Acquired	(price as of 2026-08-21)
May 11, 2022	TVTX	A	3,000	—	—	70,000 Direct	+4.48%	Acquired	(price as of 2026-08-21)
May 14, 2021	TVTX	A	3,000	—	—	67,000 Direct	+4.69%	Acquired	(price as of 2026-08-21)
May 14, 2021	TVTX	A	9,000	—	—	9,000 Direct	—	Acquired	(price as of 2026-08-21)
May 15, 2020	TVTX	A	9,000	—	—	9,000 Direct	—	Acquired	(price as of 2026-08-21)
May 15, 2020	TVTX	A	3,000	—	—	64,000 Direct	+4.92%	Acquired	(price as of 2026-08-21)
May 8, 2019	TVTX	A	8,000	—	—	8,000 Direct	—	Acquired	(price as of 2026-08-21)
May 8, 2019	TVTX	A	2,000	—	—	61,000 Direct	+3.39%	Acquired	(price as of 2026-08-21)
May 9, 2018	TVTX	A	10,000	—	—	10,000 Direct	—	Acquired	(price as of 2026-08-21)
May 9, 2018	TVTX	A	2,500	—	—	59,000 Direct	+4.42%	Acquired	(price as of 2026-08-21)
May 17, 2017	TVTX	A	10,000	—	—	10,000 Direct	—	Acquired	(price as of 2026-08-21)
May 17, 2017	TVTX	A	2,500	—	—	56,500 Direct	+4.63%	Acquired	(price as of 2026-08-21)
May 18, 2016	TVTX	A	8,000	—	—	8,000 Direct	—	Acquired	(price as of 2026-08-21)
May 18, 2016	TVTX	A	2,000	—	—	54,000 Direct	+3.85%	Acquired	(price as of 2026-08-21)
March 15, 2016	COCP	P	294,118	$0.51	$150,000	657,161 Direct	+81.01%	Acquired	-99.4% (price as of 2026-08-21)
March 4, 2016	TVTX	P	5,000	$15.31	$76,550	52,000 Direct	+10.64%	Acquired	324.4% (price as of 2026-08-21)
March 3, 2016	TVTX	P	10,000	$14.45	$144,500	47,000 Direct	+27.03%	Acquired	349.7% (price as of 2026-08-21)
Dec. 23, 2015	COCP	P	100,000	$0.58	$58,000	363,043 Direct	+38.02%	Acquired	-99.4% (price as of 2026-08-21)
Oct. 1, 2015	COCP	A	16,000,000	—	—	16,000,000 Direct	—	Acquired	(price as of 2026-08-21)
June 8, 2015	TVTX	A	8,000	—	—	8,000 Direct	—	Acquired	(price as of 2026-08-21)
June 8, 2015	TVTX	A	2,000	—	—	37,000 Direct	+5.71%	Acquired	(price as of 2026-08-21)
March 25, 2015	COCP	P	163,043	$0.92	$150,000	263,043 Direct	+163.04%	Acquired	-99.6% (price as of 2026-08-21)
March 23, 2015	COCP	A	1,750,000	—	—	1,750,000 Direct	—	Acquired	(price as of 2026-08-21)
Dec. 11, 2014	COCP	P	25,000	$0.45	$11,250	25,000 Direct	—	Acquired	-99.3% (price as of 2026-08-21)
Dec. 11, 2014	COCP	P	25,000	$0.45	$11,250	50,000 Direct	+100.00%	Acquired	-99.3% (price as of 2026-08-21)
Dec. 11, 2014	COCP	P	50,000	$0.46	$23,000	100,000 Direct	+100.00%	Acquired	-99.3% (price as of 2026-08-21)
Nov. 25, 2014	TVTX	P	15,000	$8.60	$129,000	35,000 Direct	+75.00%	Acquired	655.6% (price as of 2026-08-21)
Oct. 8, 2014	TVTX	A	40,000	—	—	40,000 Direct	—	Acquired	(price as of 2026-08-21)
Oct. 8, 2014	TVTX	A	20,000	—	—	20,000 Direct	—	Acquired	(price as of 2026-08-21)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II)

Options, RSUs and convertible securities reported on Form 4 Table II.

Date	Ticker	Security	Underlying	Exercise price	Expiration	Shares	A/D
May 15, 2025	TVTX	Stock option (right to buy)	Common Stock (19,500)	$21.15	May 15, 2035	19,500	Acquired
Sept. 30, 2024	TVTX	Stock option (right to buy)	Common Stock (40,000)	$10.48	Oct. 8, 2024	40,000	Acquired
May 8, 2024	TVTX	Stock option (right to buy) [F1]	Common Stock (19,500)	$6.82	May 7, 2034	19,500	Acquired
May 17, 2023	TVTX	Stock option (right to buy) [F1]	Common Stock (13,500)	$17.11	May 16, 2033	13,500	Acquired
May 11, 2022	TVTX	Stock option (right to buy) [F1]	Common Stock (9,000)	$21.38	May 10, 2032	9,000	Acquired
May 14, 2021	TVTX	Stock option (right to buy) [F1]	Common Stock (9,000)	$18.27	May 13, 2031	9,000	Acquired
May 15, 2020	TVTX	Employee stock option (right to buy)	Common Stock (9,000)	$15.43	May 14, 2030	9,000	Acquired
May 8, 2019	TVTX	Employee stock option (right to buy)	Common Stock (8,000)	$17.94	May 7, 2029	8,000	Acquired
May 9, 2018	TVTX	Employee Stock Option (Right to Buy)	Common Stock (10,000)	$26.52	May 8, 2028	10,000	Acquired
May 17, 2017	TVTX	Employee Stock Option (Right to Buy)	Common Stock (10,000)	$17.44	May 16, 2027	10,000	Acquired
May 18, 2016	TVTX	Employee Stock Option (Right to Buy)	Common Stock (8,000)	$16.33	May 17, 2026	8,000	Acquired
Oct. 1, 2015	COCP	Stock Option (Right to Buy)	Common Stock (16,000,000)	$0.70	Oct. 1, 2025	16,000,000	Acquired
June 8, 2015	TVTX	Employee Stock Option (Right to Buy)	Common Stock (8,000)	$32.59	June 7, 2025	8,000	Acquired
March 23, 2015	COCP	Stock Option (Right to Buy)	Common Stock (1,750,000)	$1.01	March 23, 2025	1,750,000	Acquired
Oct. 8, 2014	TVTX	Stock Option (Right to Buy)	Common Stock (40,000)	$10.48	Oct. 7, 2024	40,000	Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 7 holdings

Securities held when first becoming an insider, per SEC Form 3.

Date	Ticker	Security	Shares	Ownership
Aug. 2, 2021	INDP	Common Stock	2,460	Direct
Aug. 2, 2021	INDP	Stock Option (right to buy)→ Common Stock (1,500)	1,500	Direct
Aug. 2, 2021	INDP	Stock Option (right to buy)→ Common Stock (813)	813	Direct
Aug. 2, 2021	INDP	Stock Option (right to buy)→ Common Stock (4,750)	4,750	Direct
Aug. 2, 2021	INDP	Stock Option (right to buy)→ Common Stock (1,250)	1,250	Direct
Aug. 2, 2021	INDP	Stock Option (right to buy)→ Common Stock (1,563)	1,563	Direct
Aug. 2, 2021	INDP	Stock Option (right to buy)→ Common Stock (3,750)	3,750	Direct