COCP Cocrystal Pharma, Inc. - Common Stock

NASDAQ · Pharmaceuticals · View on SEC EDGAR ↗
$1.08
Price · Aug 19, 2026
Fundamentals as of Aug 13, 2026

COCP Stock Snapshot Price, market cap, P/E, EPS, ROE, debt/equity, 52-week range

Price
$1.08
Market Cap
$15M
P/E (TTM)
-1.4
EPS (TTM)
$-0.78
Revenue (TTM)
Div Yield
ROE
-151.4%
Debt/Equity
52W Range
$1 – $3

COCP Stock Price Chart Daily OHLCV with technical indicators — pan, zoom, and customize your view

10-Year Performance Revenue, net income, margins and EPS trends

Revenue & Net Income
2-point trend, -69.3%
2019-12-31 2020-12-31
EPS $-0.78
6-point trend, +76.4%
2016-12-31 2025-12-31
Free Cash Flow $-8M
7-point trend, +1.4%
2018-12-31 2025-12-31
Margins

Valuation P/E, P/S, P/B, EV/EBITDA ratios — is the stock expensive or cheap?

Metric
5Y trend
COCP
Peer Median
P/E (TTM)
5-point trend, +98.5%
-1.4
44.2
P/S (TTM)
5-point trend, -98.8%
7.5
8.2
P/B
5-point trend, -90.3%
2.4
2.1
Price / FCF
5-point trend, +98.6%
-1.8

Profitability Gross, operating and net margins; ROE, ROA, ROIC

Metric
5Y trend
COCP
Peer Median
ROA
5-point trend, -227.0%
-76.2%
-49.9%
ROE
5-point trend, -705.9%
-151.4%
-51.4%

Financial Health Debt, liquidity, solvency — balance sheet strength

Metric
5Y trend
COCP
Peer Median
Current Ratio
5-point trend, -85.3%
3.7
3.7
Quick Ratio
5-point trend, -87.1%
3.2

Growth Revenue, EPS and net income growth: YoY, 3Y CAGR, 5Y CAGR

Metric
5Y trend
COCP
Peer Median

Per Share Metrics EPS, book value per share, cash flow per share, dividend per share

Metric
5Y trend
COCP
Peer Median
EPS (Diluted)
5-point trend, -2500.0%
$-0.78

Capital Efficiency Asset turnover, inventory turnover, receivables turnover

Metric
5Y trend
COCP
Peer Median

COCP Analyst Consensus Bullish and bearish analyst opinions, 12-month price target, upside

BUY 7 analysts
  • Strong Buy 2 28.6%
  • Buy 4 57.1%
  • Hold 1 14.3%
  • Sell 0 0.0%
  • Strong Sell 0 0.0%

12-Month Price Target

2 analysts · 2026-08-18
Median target $9.00 +733.3%
Mean target $9.00 +733.3%

Earnings History EPS actual vs estimate, surprise %, beat rate, next earnings date

Avg Surprise
0.10%
Period EPS Actual EPS Est Surprise
March 31, 2026 $-0.17 $-0.15 -0.02%
Dec. 31, 2025 $-0.17 $-0.18 0.01%
Sept. 30, 2025 $-0.19 $-0.21 0.02%
June 30, 2025 $-0.20 $-0.31 0.11%
March 31, 2025 $-0.23 $-0.52 0.29%
Dec. 31, 2024 $-0.32 $-0.54 0.22%

Peer comparison (GICS sub-industry) Key metrics vs sector peers

Ticker Market Cap P/E Rev YoY Net Margin ROE Gross Margin
COCP $14M -1.3 -151.4%
TXMD $19M -32.6 71.6% -18.8% -2.1%
QCLS -0.5
BFRI
CALC -3.3 -29.7%
RKTO
LLY 46.8 44.7% 31.7% 101.2%

Full Fundamentals All metrics by year — income statement, balance sheet, cash flow

Income Statement 16
Annual Income Statement data for COCP
Metric Trend 202520242023202220212020201920182017201620152014
Revenue 2-point trend, -69.3% · · · · · $2M $7M · · · · ·
R&D Expense 12-point trend, +24.2% $5M $13M $15M $12M $9M $6M $4M $5M $6M $102M $47M $4M
SG&A Expense 12-point trend, +128.2% $4M $5M $6M $6M $5M $6M $5M $4M $2M $4M $7M $2M
Operating Expenses 12-point trend, +55.3% $9M $18M $19M $39M $14M $12M $55M $63M $8M $106M $54M $6M
Operating Income 12-point trend, -55.5% $-9M $-18M $-19M $-39M $-14M $-10M $-48M $-63M $-8M $-106M $-54M $-6M
Interest Expense 6-point trend, -1203.4% · · $-640.0K $2.0K $4.0K $8.0K $19.0K $58.0K · · · ·
Interest Income 4-point trend, -107.3% · · · · · · · · $-7.0K $126.0K $180.0K $96.0K
Other Non-op 12-point trend, -96.7% $188.0K $374.0K $575.0K $-8.0K $36.0K $-62.0K $237.0K $294.0K $769.0K $2M $-11M $6M
Pretax Income 9-point trend, -5748.3% $-9M $-19M · · · $-10M $-48M $-63M $-7M $-104M $-65M $-151.0K
Income Tax 5-point trend, -26019.2% · · · · · · · $-14M $-7M $-29M $-15M $-52.0K
Net Income 12-point trend, -8820.2% $-9M $-18M $-18M $-39M $-14M $-10M $-48M $-49M $-613.0K $-75M $-50M $-99.0K
EPS (Basic) 9-point trend, -0.78 $-0.78 $-1.72 $-1.87 $-4.77 $-0.16 · · · $-0.03 $-3.18 $-2.40 $0.00
EPS (Diluted) 8-point trend, -7700.0% $-0.78 $-1.72 $-1.87 $-4.77 · · · · $-0.03 $-3.30 $-2.40 $-0.01
Shares (Basic) 11-point trend, -96.5% 11,290,000 10,174,000 9,651,000 8,143,000 7,364,000 · 31,859 28,009 24,126,000 23,518,000 21,011,000 326,779,000
Shares (Diluted) 8-point trend, -96.6% 11,290,000 10,174,000 9,651,000 8,143,000 · · · · 24,126,000 23,533,000 21,011,000 327,753,000
EBITDA 7-point trend, +85.7% $-9M $-18M · $-39M $-14M $-10M $-48M $-63M · · · ·
Balance Sheet 24
Annual Balance Sheet data for COCP
Metric Trend 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +77.0% $7M $10M $26M $37M $59M $33M $7M $3M $748.0K $4M $9M $4M
Short-term Investments · · · · · · · · · · · $2M
Receivables 6-point trend, +355.7% · · · · · $556.0K $644.0K · $1.0K $21.0K $32.0K $122.0K
Prepaid Expense 12-point trend, +127.8% $328.0K $430.0K $2M $2M $568.0K $399.0K $169.0K $191.0K $105.0K $517.0K $441.0K $144.0K
Current Assets 12-point trend, +27.6% $8M $12M $29M $40M $59M $34M $8M $3M $2M $5M $10M $6M
PP&E (Net) 12-point trend, -67.3% $93.0K $153.0K $271.0K $342.0K $453.0K $591.0K $431.0K $384.0K $119.0K $280.0K $430.0K $284.0K
PP&E (Gross) 12-point trend, +69.8% $2M $2M $2M $2M $2M $2M $2M $1M $1M $2M $2M $1M
Accum. Depreciation 12-point trend, +110.9% $2M $2M $2M $2M $1M $1M $1M $983.0K $1M $1M $1M $949.0K
Goodwill 8-point trend, -70.7% · · · · $19M $19M $19M $65M $65M $65M $65M $65M
Total Assets 12-point trend, -96.3% $10M $13M $31M $41M $79M $54M $29M $69M $121M $125M $224M $259M
Accounts Payable 11-point trend, +197.7% $890.0K $2M $1M $614.0K $578.0K $657.0K $2M $616.0K $494.0K $563.0K · $299.0K
Accrued Liabilities 3-point trend, -18.8% · · · · · · · · · $563.0K $3M $693.0K
Current Liabilities 12-point trend, -75.9% $2M $2M $3M $1M $2M $1M $2M $2M $1M $2M $7M $9M
Capital Leases 7-point trend, +123.9% $1M $2M $2M $57.0K $291.0K $345.0K $523.0K · · · · ·
Deferred Tax 4-point trend, -79.2% · · · · · · · · $14M $20M $50M $65M
Total Liabilities 12-point trend, -95.5% $3M $4M $5M $1M $2M $2M $3M $2M $16M $23M $57M $74M
Long-term Debt 2-point trend, -23.5% · · · · · · · · · · $50M $65M
Common Stock 12-point trend, -89.4% $13.0K $10.0K $10.0K $8.0K $8.0K $71.0K $36.0K $30.0K $24.0K $24.0K $694.0K $123.0K
Paid-in Capital 4-point trend, +1200.0% · · · · · · · · $243M $240M $229M $19M
Retained Earnings 12-point trend, -2652.5% $-342M $-333M $-316M $-298M $-259M $-245M $-235M $-187M $-138M $-137M $-63M $-12M
AOCI 2-point trend, -100.0% · · · · · · · · · · $0 $236.0K
Stockholders' Equity 12-point trend, -4.8% $6M $10M $26M $40M $78M $53M $26M $67M $105M $102M $168M $7M
Liabilities + Equity 12-point trend, -96.3% $10M $13M $31M $41M $79M $54M $29M $69M $121M $125M $224M $259M
Shares Outstanding 12-point trend, +11152.8% 13,784,000 10,174,000 10,174,000 8,143,000 8,143,000 70,439,000 35,150,000 29,938,000 24,275,000 23,801,000 694,396,000 122,494
Cash Flow 12
Annual Cash Flow data for COCP
Metric Trend 202520242023202220212020201920182017201620152014
D&A 12-point trend, -63.8% $72.0K $126.0K $189.0K $185.0K $190.0K $157.0K $98.0K $6.0K $101.0K $201.0K $192.0K $199.0K
Stock-based Comp 12-point trend, +610.5% $270.0K $643.0K $801.0K $855.0K $724.0K $662.0K $351.0K $562.0K $614.0K $548.0K $3M $38.0K
Deferred Tax 6-point trend, -25051.9% · · · · · · $-14M $-14M $-7M $-29M $-15M $-54.0K
Operating Cash Flow 12-point trend, -36.3% $-8M $-16M $-15M $-21M $-13M $-10M $-2M $-8M $-7M $-15M $-10M $-6M
CapEx 12-point trend, +140.0% $12.0K $8.0K $118.0K $74.0K $52.0K $240.0K $145.0K $28.0K $40.0K $51.0K $339.0K $5.0K
Investing Cash Flow 12-point trend, -100.2% $-12.0K $-8.0K $-118.0K $-74.0K $-52.0K $-240.0K $-145.0K $1M $-40.0K $3.0K $-262.0K $6M
Stock Issued 9-point trend, -99.0% $154.0K · $4M · $39M $36M $7M $8M $3M $9M $16M ·
Net Stock Activity 5-point trend, -98.0% $154.0K · · · $39M $36M $7M $8M · · · ·
Financing Cash Flow 11-point trend, +87.3% $5M · $4M $-27.0K $38M $36M $6M $9M $4M $9M $16M $3M
Net Change in Cash 12-point trend, -196.6% $-3M $-16M $-11M $-22M $26M $26M $5M $2M $-3M $-6M $5M $3M
Free Cash Flow 7-point trend, +1.4% $-8M $-16M · $-22M $-13M $-10M $-2M $-8M · · · ·
Levered FCF · · · · · · · $-8M · · · ·
Profitability 7
Annual Profitability data for COCP
Metric Trend 202520242023202220212020201920182017201620152014
Operating Margin 3-point trend, -100.4% · · · · · -476.0% -737.5% 108489.7% · · · ·
Net Margin 3-point trend, -100.6% · · · · · -479.0% -733.8% 84565.5% · · · ·
Pretax Margin 3-point trend, -100.4% · · · · · -479.0% -733.8% 107982.8% · · · ·
EBITDA Margin 3-point trend, -100.4% · · · · · -476.0% -737.5% 108489.7% · · · ·
ROA 7-point trend, -47.6% -76.2% -78.3% · -64.6% -21.2% -23.3% -99.2% -51.6% · · · ·
ROE 7-point trend, -174.4% -151.4% -157.5% · -86.8% -17.9% -18.8% -99.9% -55.2% · · · ·
ROIC · · · · · · · -73.7% · · · ·
Liquidity & Solvency 3
Annual Liquidity & Solvency data for COCP
Metric Trend 202520242023202220212020201920182017201620152014
Current Ratio 7-point trend, +94.7% 3.7 4.8 · 33.0 38.4 25.0 3.6 1.9 · · · ·
Quick Ratio 7-point trend, +81.8% 3.2 4.1 · 30.6 38.0 24.7 3.5 1.7 · · · ·
Interest Coverage 4-point trend, -1689.5% · · · -19414.5 -3555.2 -1198.2 · -1084.9 · · · ·
Efficiency 2
Annual Efficiency data for COCP
Metric Trend 202520242023202220212020201920182017201620152014
Asset Turnover 3-point trend, +8216.7% · · · · · 0.0 0.1 -0.0 · · · ·
Receivables Turnover 2-point trend, -83.5% · · · · · 3.4 20.4 · · · · ·
Per Share 4
Annual Per Share data for COCP
Metric Trend 202520242023202220212020201920182017201620152014
Book Value / Share 7-point trend, -79.4% $0.46 $0.94 · $4.86 $0.80 $0.75 $0.73 $2.23 · · · ·
Cash Flow / Share 2-point trend, +55.2% $-0.73 $-1.62 · · · · · · · · · ·
Cash / Share 7-point trend, +460.0% $0.51 $0.97 · $4.57 $0.60 $0.47 $0.21 $0.09 · · · ·
EPS (TTM) 10-point trend, -7700.0% $-0.78 $-1.72 $-1.87 $-4.77 · · $-0.07 $0.03 $-0.03 $-3.30 $-2.40 $-0.01
Valuation (TTM) 10
Annual Valuation (TTM) data for COCP
Metric Trend 202520242023202220212020201920182017201620152014
Revenue TTM 10-point trend, +2459.0% $2M $2M $2M $2M $2M $2M $7M $78.0K $78.0K $78.0K · ·
Net Income TTM 12-point trend, -8820.2% $-9M $-18M $-18M $-39M $-14M $-10M $-48M $-49M $-613.0K $-75M $-50M $-99.0K
Market Cap 7-point trend, -99.0% $14M $21M · $16M $760M $1.15B $211M $1.29B · · · ·
P/E 10-point trend, +100.0% -1.3 -1.2 -0.9 -0.4 · · -85.7 1440.0 -2400.0 -42.5 -133.5 -15120.0
P/S 7-point trend, -100.0% 6.8 10.3 · 8.0 380.9 570.8 32.1 16581.0 · · · ·
P/B 7-point trend, -89.0% 2.1 2.2 · 0.4 9.8 21.9 8.2 19.3 · · · ·
P / Tangible Book 6-point trend, -93.8% 2.1 2.2 0.7 0.4 13.0 34.4 · · · · · ·
P / Cash Flow 7-point trend, +98.9% -1.6 -1.2 · -0.7 -59.8 -116.9 -134.9 -156.0 · · · ·
P / FCF 7-point trend, +98.9% -1.6 -1.2 · -0.7 -59.5 -114.2 -123.5 -155.5 · · · ·
Earnings Yield 10-point trend, -795800.0% -79.6% -85.2% -108.7% -244.6% · · -1.2% 0.07% -0.04% -2.4% -0.75% -0.01%

Financial Statements Income statement, balance sheet, cash flow — annual, last 5 years

Income Statement
2025-12-312024-12-312023-12-312022-12-312021-12-31
Net Income $-9M$-18M$-18M$-39M$-14M
Diluted EPS $-0.78$-1.72$-1.87$-4.77
Balance Sheet
2025-12-312024-12-312023-12-312022-12-312021-12-31
Current Ratio 3.74.833.038.4
Quick Ratio 3.24.130.638.0
Cash Flow
2025-12-312024-12-312023-12-312022-12-312021-12-31
Free Cash Flow $-8M$-16M$-22M$-13M

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Institutional owners (13F) 28 filers · $1.2M total · As of June 30, 2026

Institutions that report holding this stock in their quarterly SEC Form 13F. Long positions only; a single filer may appear twice for separate option legs. Large offsetting put/call legs typically reflect market-making or hedged inventory, not directional conviction.

Institutional activity — Q2 2026 vs prior quarter
New positions Exited positions Increased Decreased Net shares change
8 (+4 vs prior Q) 6 (+3 vs prior Q) 2 (-3 vs prior Q) 7 (+2 vs prior Q) +340K

Compared to Q1 2026. SEC Form 13F filings are due within 45 days of quarter-end plus a short buffer for late filers — quarters still inside that window are skipped in favor of the most recent fully-reported pair.

Institution Value Shares % of tracked 13F Type
VANGUARD CAPITAL MANAGEMENT LLC $376,139 358,228 32.52% Shares
RENAISSANCE TECHNOLOGIES LLC $188,609 179,628 16.31% Shares
TWO SIGMA INVESTMENTS, LP $184,148 175,379 15.92% Shares
BlackRock, Inc. $77,433 73,746 6.70% Shares
GEODE CAPITAL MANAGEMENT, LLC $74,175 70,628 6.41% Shares
CITADEL ADVISORS LLC $47,374 45,118 4.10% Shares
NEUBERGER BERMAN GROUP LLC $33,480 31,886 2.89% Shares
XTX Topco Ltd $30,809 29,342 2.66% Shares
VANGUARD FIDUCIARY TRUST CO $25,217 24,016 2.18% Shares
JANE STREET GROUP, LLC $23,777 22,645 2.06% Shares
VANGUARD GROUP INC $23,512 24,016 2.03% Shares
STATE STREET CORP $21,570 20,543 1.87% Shares
Parallel Advisors, LLC $13,197 12,569 1.14% Shares
NORTHERN TRUST CORP $12,517 11,921 1.08% Shares
Ground Swell Capital, LLC $11,290 10,752 0.98% Shares
WELLS FARGO & COMPANY/MN $6,564 6,251 0.57% Shares
Tower Research Capital LLC (TRC) $4,183 3,984 0.36% Shares
MORGAN STANLEY $915 871 0.08% Shares
NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO $858 817 0.07% Shares
Clean Yield Group $439 418 0.04% Shares
UBS Group AG $125 119 0.01% Shares
NVWM, LLC $88 84 0.01% Shares
BARCLAYS PLC $44 42 0.00% Shares
SBI Securities Co., Ltd. $35 33 0.00% Shares
HRT FINANCIAL LP $21 20,336 0.00% Shares
VIMA LLC $18 17 0.00% Shares
ROYAL BANK OF CANADA $0 9 0.00% Shares
Motiv8 Investments LLC $0 42 0.00% Shares

Company insiders 2 insiders · 0 officers · 0 directors

Insider Role Last activity Shares owned Buys 12m Sells 12m Net 12m
Phillip Frost, M.D. Aug. 5, 2026 P 1,993,551 2 0 $80,300
James Sapirstein June 3, 2026 A 0 0 $0

Insiders from SEC Form 3/4/5 filings; net = open-market P/S only

Activists & 5%+ owners 4 positions

Investors who filed SEC Schedule 13D — beneficial ownership above 5% with an intent to influence the issuer (activist stakes, board campaigns, M&A). Each row shows the most recent known state of that filer's position.

Filer Filed Stake Status Purpose Filing
Phillip Frost, M.D., Frost Gamma Investments Trust ×6 filings Aug. 7, 2026 13.90% Amendment Passive investment SEC
OPKO HEALTH, INC., FROST PHILLIP MD ET AL, Frost Gamma Investments Trust, Rubin Steven D ×5 filings Aug. 7, 2026 29.60% Initial filing Passive investment SEC
FiveT Investment Management Ltd, FiveT Capital AG May 25, 2021 Initial filing SEC
Raymond F. Schinazi, Phillip Frost, M.D., Frost Gamma Investments Trust, Gary Wilcox, Roger Kornberg, Steven D. Rubin ×3 filings March 19, 2019 Initial filing SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

ETF ownership Held by 2 ETFs

Weight reflects direct equity holdings (N-PORT) only; leveraged or derivative-based funds may hold additional swap exposure not shown.

Fund Weight Units As of Source
VXF · VANGUARD INDEX FUNDS July 15, 2026 Daily
VTI · VANGUARD INDEX FUNDS July 15, 2026 Daily