Insider at

04

Insider transactions

05
0 buys (P) 0 sells (S) Net: $0 + 80 non-open-market transactions below last 12 months, based on the transactions shown below

Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted

80 other filings hidden
DateTickerCodeSharesPriceValue Owned afterΔ ownA/Dvs now
June 8, 2023 KYNB S 10b5-1 6,225 $17.68 $110,058 31,501 Direct -16.50% Disposed -98.6% (price as of 2026-10-05)
June 8, 2023 KYNB S 10b5-1 2,295 $16.79 $38,533 37,726 Direct -5.73% Disposed -98.5% (price as of 2026-10-05)

P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding

Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.

Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.

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DateTickerSecurityUnderlying Exercise priceExpirationSharesA/D
June 18, 2026 AGIO Stock options (right to buy) Common stock (14,950) $34.16 June 18, 2036 14,950 Acquired
June 18, 2026 AGIO Restricted stock units Common stock (2,927) · · 2,927 Acquired
June 18, 2026 AGIO Restricted stock units Common stock (2,816) · · 2,816 Disposed
June 12, 2026 KYNB Stock Option (Right to Buy) Common Stock (7,000) $7.13 June 11, 2036 7,000 Acquired
May 27, 2026 NMRA Stock Option (Right to Buy) Common Stock (80,000) $1.86 May 26, 2036 80,000 Acquired
June 20, 2025 AGIO Restricted stock units Common stock (2,120) · · 2,120 Disposed
June 18, 2025 AGIO Restricted stock units Common stock (2,816) · · 2,816 Acquired
June 18, 2025 AGIO Stock options (right to buy) Common stock (15,768) $35.50 June 18, 2035 15,768 Acquired
June 4, 2025 KYNB Stock Option (Right to Buy) Common Stock (120,000) $0.31 June 3, 2035 120,000 Acquired
May 28, 2025 NMRA Stock Option (Right to Buy) Common Stock (80,000) $0.72 May 27, 2035 80,000 Acquired
May 28, 2025 NMRA Stock Option (Right to Buy) Common Stock (28,571) · June 13, 2034 28,571 Acquired
May 28, 2025 NMRA Stock Option (Right to Buy) Common Stock (27,802) · Sept. 14, 2033 27,802 Acquired
May 28, 2025 NMRA Stock Option (Right to Buy) Common Stock (95,586) · April 23, 2031 95,586 Acquired
May 28, 2025 NMRA Stock Option (Right to Buy) Common Stock (28,571) $1.69 June 13, 2034 28,571 Disposed
May 28, 2025 NMRA Stock Option (Right to Buy) Common Stock (27,802) $1.69 Sept. 14, 2033 27,802 Disposed
May 28, 2025 NMRA Stock Option (Right to Buy) Common Stock (95,586) $1.69 April 23, 2031 95,586 Disposed
Feb. 13, 2025 NMRA Stock Option (Right to Buy) Common Stock (28,571) · June 13, 2034 28,571 Acquired
Feb. 13, 2025 NMRA Stock Option (Right to Buy) Common Stock (27,802) · Sept. 14, 2033 27,802 Acquired
Feb. 13, 2025 NMRA Stock Option (Right to Buy) Common Stock (95,586) · April 23, 2031 95,586 Acquired
Feb. 13, 2025 NMRA Stock Option (Right to Buy) Common Stock (28,571) $9.95 June 13, 2034 28,571 Disposed
Feb. 13, 2025 NMRA Stock Option (Right to Buy) Common Stock (27,802) $17.00 Sept. 14, 2033 27,802 Disposed
Feb. 13, 2025 NMRA Stock Option (Right to Buy) Common Stock (95,586) $2.51 April 23, 2031 95,586 Disposed
June 20, 2024 AGIO Restricted stock units Common stock (2,120) · · 2,120 Acquired
June 20, 2024 AGIO Stock options (right to buy) Common stock (11,774) $42.45 June 20, 2034 11,774 Acquired
June 13, 2024 AGIO Restricted stock units Common stock (3,388) · · 3,388 Disposed
June 13, 2024 NMRA Stock Option (Right to Buy) Common Stock (28,571) $9.95 June 12, 2034 28,571 Acquired
June 5, 2024 KYNB Stock Option (Right to Buy) Common Stock (70,000) $1.21 June 4, 2034 70,000 Acquired
Sept. 14, 2023 NMRA Stock Option (Right to Buy) Common Stock (27,802) $17.00 Sept. 13, 2033 27,802 Acquired
June 21, 2023 AGIO Restricted stock unit Common stock (4,975) · · 4,975 Disposed
June 13, 2023 AGIO Restricted stock units Common stock (3,388) · · 3,388 Acquired
June 13, 2023 AGIO Stock options (right to buy) Common stock (18,958) $26.56 June 13, 2033 18,958 Acquired
June 7, 2023 KYNB Stock Option (Right to Buy) Common Stock (12,666) $17.13 June 6, 2033 12,666 Acquired
June 21, 2022 AGIO Restricted stock unit Common stock (4,975) · · 4,975 Acquired
June 21, 2022 AGIO Stock options (right to buy) Common stock (29,307) $18.09 June 21, 2032 29,307 Acquired
June 16, 2022 KYNB Stock Option (Right to Buy) Common Stock (25,684) $9.00 June 15, 2032 25,684 Acquired
May 20, 2022 AGIO Restricted stock unit Common stock (1,585) · · 1,585 Disposed
May 28, 2021 AGIO Restricted stock units Common stock (1,686) · · 1,686 Disposed
May 26, 2021 KYNB Stock Option (Right to Buy) Common Stock (7,800) $20.86 May 25, 2031 7,800 Acquired
May 20, 2021 AGIO Restricted stock unit Common stock (1,585) · · 1,585 Acquired
May 20, 2021 AGIO Stock options (right to buy) Common stock (8,888) $56.76 May 20, 2031 8,888 Acquired
June 4, 2020 KYNB Stock Option (Right to Buy) Common Stock (7,800) $32.69 June 3, 2030 7,800 Acquired
May 29, 2020 AGIO Restricted stock units Common stock (1,878) · · 1,878 Disposed
May 28, 2020 AGIO Stock options (right to buy) Common stock (8,096) $53.35 May 28, 2030 8,096 Acquired
May 28, 2020 AGIO Restricted stock units Common stock (1,686) · · 1,686 Acquired
June 5, 2019 KYNB Stock Option (Right to Buy) Common Stock (7,800) $39.03 June 5, 2029 7,800 Acquired
May 31, 2019 AGIO Restricted stock units Common stock (1,400) · · 1,400 Disposed
May 29, 2019 AGIO Restricted stock units Common stock (1,878) · · 1,878 Acquired
May 29, 2019 AGIO Stock option (right to buy) Common stock (8,919) $47.91 May 29, 2029 8,919 Acquired
Dec. 6, 2018 KYNB Stock Option (Right to Buy) Common Stock (3,008) $40.93 Dec. 6, 2028 3,008 Acquired
Dec. 6, 2018 KYNB Stock Option (Right to Buy) Common Stock (10,400) $40.93 Dec. 6, 2028 10,400 Acquired
Dec. 5, 2018 KYNB Stock Option (Right to Buy) Common Stock (3,008) $41.34 Dec. 5, 2028 3,008 Acquired
Dec. 5, 2018 KYNB Stock Option (Right to Buy) Common Stock (10,400) $41.34 Dec. 5, 2028 10,400 Acquired
May 31, 2018 AGIO Restricted stock units Common stock (1,400) · · 1,400 Acquired
May 31, 2018 AGIO Stock option (right to buy) Common stock (5,700) $93.50 May 30, 2028 5,700 Acquired
June 13, 2017 AGIO Stock option (right to buy) Common stock (8,000) $50.73 June 12, 2027 8,000 Acquired
June 21, 2016 AGIO Stock option (right to buy) Common stock (8,000) $47.33 June 20, 2026 8,000 Acquired
June 23, 2015 AGIO Stock Option (right to buy) Common stock (21,250) $103.63 June 22, 2025 21,250 Acquired

Exercise/conversion price is blank when not applicable (e.g. RSUs).

Initial ownership (Form 3) 1 holding

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Securities held when first becoming an insider, per SEC Form 3.

DateTickerSecuritySharesOwnership
Sept. 14, 2023 NMRA Stock Option (Right to Buy)→ Common Stock · Direct