William D. Waddill
Insider
First SEC filing: June 11, 2026 · Latest: June 11, 2026
Insider at
Insider transactions
0 buys (P)
9 sells (S)
Net: $-6,146,459
Price change vs current quote, split-adjusted for corporate actions since the filing — not benchmarked, not annualized, not size-weighted
| Date | Ticker | Code | Shares | Price | Value | Owned after | Δ own | A/D | vs now |
|---|---|---|---|---|---|---|---|---|---|
| June 23, 2026 | PTGX | M | 9,000 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-05) |
| June 23, 2026 | PTGX | S 10b5-1 | 9,000 | $117.94 | $1,061,460 | 7,825 Direct | -53.49% | Disposed | 19.2% (price as of 2026-10-05) |
| June 23, 2026 | PTGX | M 10b5-1 | 9,000 | $16.54 | $148,860 | 16,825 Direct | +115.02% | Acquired | 750.2% (price as of 2026-10-05) |
| June 11, 2026 | ANNX | A | 65,000 | · | · | 65,000 Direct | · | Acquired | (price as of 2026-10-05) |
| June 10, 2026 | PTGX | M | 6,000 | · | · | 9,000 Direct | -40.00% | Disposed | (price as of 2026-10-05) |
| June 10, 2026 | PTGX | M | 3,000 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-05) |
| June 10, 2026 | PTGX | S 10b5-1 | 9,000 | $107.68 | $969,120 | 7,825 Direct | -53.49% | Disposed | 30.6% (price as of 2026-10-05) |
| June 10, 2026 | PTGX | M 10b5-1 | 6,000 | $16.54 | $99,240 | 16,825 Direct | +55.43% | Acquired | 750.2% (price as of 2026-10-05) |
| June 10, 2026 | PTGX | M 10b5-1 | 3,000 | $11.80 | $35,400 | 10,825 Direct | +38.34% | Acquired | 1091.8% (price as of 2026-10-05) |
| May 29, 2026 | PTGX | M | 9,000 | · | · | 3,000 Direct | -75.00% | Disposed | (price as of 2026-10-05) |
| May 29, 2026 | PTGX | S 10b5-1 | 9,000 | $99.64 | $896,760 | 7,825 Direct | -53.49% | Disposed | 41.1% (price as of 2026-10-05) |
| May 29, 2026 | PTGX | M 10b5-1 | 9,000 | $11.80 | $106,200 | 16,825 Direct | +115.02% | Acquired | 1091.8% (price as of 2026-10-05) |
| Feb. 6, 2026 | PTGX | M | 20,000 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-05) |
| Feb. 6, 2026 | PTGX | S | 20,000 | $83.68 | $1,673,600 | 7,825 Direct | -71.88% | Disposed | 68.1% (price as of 2026-10-05) |
| Feb. 6, 2026 | PTGX | M | 20,000 | $8.31 | $166,200 | 27,825 Direct | +255.59% | Acquired | 1592.3% (price as of 2026-10-05) |
| Jan. 2, 2026 | PTGX | A | 2,695 | · | · | 7,825 Direct | +52.53% | Acquired | (price as of 2026-10-05) |
| Jan. 2, 2026 | PTGX | A | 3,762 | · | · | 3,762 Direct | · | Acquired | (price as of 2026-10-05) |
| Dec. 19, 2025 | ARWR | S 10b5-1 | 2,416 | $66.66 | $161,051 | 62,514 Direct | -3.72% | Disposed | -6.5% (price as of 2026-10-05) |
| Dec. 19, 2025 | ARWR | S 10b5-1 | 5,451 | $68.01 | $370,723 | 57,063 Direct | -8.72% | Disposed | -8.3% (price as of 2026-10-05) |
| Dec. 19, 2025 | ARWR | S 10b5-1 | 500 | $68.53 | $34,265 | 56,563 Direct | -0.88% | Disposed | -9.0% (price as of 2026-10-05) |
| Dec. 16, 2025 | ARWR | A | 7,819 | · | · | 64,930 Direct | +13.69% | Acquired | (price as of 2026-10-05) |
| Oct. 10, 2025 | PTGX | M | 12,000 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-05) |
| Oct. 10, 2025 | PTGX | S 10b5-1 | 8,000 | $87.81 | $702,480 | 5,130 Direct | -60.93% | Disposed | 60.2% (price as of 2026-10-05) |
| Oct. 10, 2025 | PTGX | S 10b5-1 | 4,000 | $69.25 | $277,000 | 13,130 Direct | -23.35% | Disposed | 103.1% (price as of 2026-10-05) |
| Oct. 10, 2025 | PTGX | M | 12,000 | $6.98 | $83,760 | 17,130 Direct | +233.92% | Acquired | 1914.8% (price as of 2026-10-05) |
| Sept. 22, 2025 | PTGX | S 10b5-1 | 4,000 | $64.25 | $257,000 | 5,130 Direct | -43.81% | Disposed | 118.9% (price as of 2026-10-05) |
| Aug. 27, 2025 | PTGX | S 10b5-1 | 4,000 | $59.25 | $237,000 | 9,130 Direct | -30.46% | Disposed | 137.4% (price as of 2026-10-05) |
| June 5, 2025 | ANNX | A | 55,000 | · | · | 55,000 Direct | · | Acquired | (price as of 2026-10-05) |
| March 17, 2025 | PTGX | S 10b5-1 | 4,000 | $54.25 | $217,000 | 13,130 Direct | -23.35% | Disposed | 159.2% (price as of 2026-10-05) |
| Jan. 2, 2025 | PTGX | A | 6,584 | · | · | 6,584 Direct | · | Acquired | (price as of 2026-10-05) |
| Jan. 2, 2025 | PTGX | A | 5,130 | · | · | 17,130 Direct | +42.75% | Acquired | (price as of 2026-10-05) |
| Dec. 18, 2024 | ARWR | A | 16,733 | $22.99 | $384,692 | 57,111 Direct | +41.44% | Acquired | 171.2% (price as of 2026-10-05) |
| Dec. 17, 2024 | ARWR | S 10b5-1 | 3,747 | $22.04 | $82,584 | 40,378 Direct | -8.49% | Disposed | 182.9% (price as of 2026-10-05) |
| Dec. 16, 2024 | ARWR | S 10b5-1 | 3,748 | $21.90 | $82,081 | 44,125 Direct | -7.83% | Disposed | 184.7% (price as of 2026-10-05) |
| Sept. 10, 2024 | PTGX | M | 8,000 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-05) |
| Sept. 10, 2024 | PTGX | S 10b5-1 | 8,000 | $45.00 | $360,000 | 12,000 Direct | -40.00% | Disposed | 212.5% (price as of 2026-10-05) |
| Sept. 10, 2024 | PTGX | M | 8,000 | $12.88 | $103,040 | 20,000 Direct | +66.67% | Acquired | 991.8% (price as of 2026-10-05) |
| July 24, 2024 | PTGX | M | 8,000 | · | · | 8,000 Direct | -50.00% | Disposed | (price as of 2026-10-05) |
| July 24, 2024 | PTGX | S 10b5-1 | 8,000 | $40.00 | $320,000 | 12,000 Direct | -40.00% | Disposed | 251.6% (price as of 2026-10-05) |
| July 24, 2024 | PTGX | M | 8,000 | $12.88 | $103,040 | 20,000 Direct | +66.67% | Acquired | 991.8% (price as of 2026-10-05) |
| June 7, 2024 | PTGX | M | 8,000 | · | · | 16,000 Direct | -33.33% | Disposed | (price as of 2026-10-05) |
| June 7, 2024 | PTGX | S 10b5-1 | 8,000 | $35.00 | $280,000 | 12,000 Direct | -40.00% | Disposed | 301.8% (price as of 2026-10-05) |
| June 7, 2024 | PTGX | M | 8,000 | $12.88 | $103,040 | 20,000 Direct | +66.67% | Acquired | 991.8% (price as of 2026-10-05) |
| June 5, 2024 | ANNX | A | 44,000 | · | · | 44,000 Direct | · | Acquired | (price as of 2026-10-05) |
| March 1, 2024 | PTGX | M | 12,975 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-05) |
| March 1, 2024 | PTGX | S 10b5-1 | 12,975 | $31.34 | $406,636 | 12,000 Direct | -51.95% | Disposed | 348.7% (price as of 2026-10-05) |
| March 1, 2024 | PTGX | M | 12,975 | $6.09 | $79,018 | 24,975 Direct | +108.12% | Acquired | 2209.2% (price as of 2026-10-05) |
| Jan. 11, 2024 | ARWR | S 10b5-1 | 2,634 | $37.81 | $99,592 | 49,170 Direct | -5.08% | Disposed | 64.9% (price as of 2026-10-05) |
| Jan. 11, 2024 | ARWR | S 10b5-1 | 1,300 | $38.59 | $50,167 | 47,870 Direct | -2.64% | Disposed | 61.6% (price as of 2026-10-05) |
| Jan. 2, 2024 | PTGX | A | 25,700 | · | · | 25,700 Direct | · | Acquired | (price as of 2026-10-05) |
| Dec. 15, 2023 | ARWR | A | 14,987 | $25.41 | $380,820 | 51,804 Direct | +40.71% | Acquired | 145.4% (price as of 2026-10-05) |
| June 8, 2023 | ANNX | A | 24,000 | · | · | 24,000 Direct | · | Acquired | (price as of 2026-10-05) |
| Jan. 16, 2023 | PTGX | A | 30,000 | · | · | 30,000 Direct | · | Acquired | (price as of 2026-10-05) |
| Jan. 10, 2023 | ARWR | A | 4,593 | · | · | 4,593 Direct | · | Acquired | (price as of 2026-10-05) |
| Jan. 10, 2023 | ARWR | A | 7,867 | · | · | 36,817 Direct | +27.17% | Acquired | (price as of 2026-10-05) |
| Jan. 9, 2023 | ARWR | S 10b5-1 | 3,200 | $30.00 | $96,000 | 28,950 Direct | -9.95% | Disposed | 107.8% (price as of 2026-10-05) |
| June 9, 2022 | ANNX | A | 24,000 | · | · | 24,000 Direct | · | Acquired | (price as of 2026-10-05) |
| May 26, 2022 | PTGX | A | 20,000 | · | · | 20,000 Direct | · | Acquired | (price as of 2026-10-05) |
| May 3, 2022 | PTGX | M | 12,000 | · | · | 0 Direct | -100.00% | Disposed | (price as of 2026-10-05) |
| May 3, 2022 | PTGX | M | 12,000 | $8.59 | $103,080 | 12,000 Direct | · | Acquired | 1537.1% (price as of 2026-10-05) |
| Jan. 7, 2022 | ARWR | A | 6,400 | · | · | 32,150 Direct | +24.85% | Acquired | (price as of 2026-10-05) |
| Jan. 3, 2022 | ARWR | S 10b5-1 | 272 | $66.25 | $18,020 | 25,750 Direct | -1.05% | Disposed | -5.9% (price as of 2026-10-05) |
| Jan. 3, 2022 | ARWR | S 10b5-1 | 2,128 | $65.01 | $138,341 | 26,022 Direct | -7.56% | Disposed | -4.1% (price as of 2026-10-05) |
| Jan. 3, 2022 | ARWR | S 10b5-1 | 2,100 | $64.23 | $134,883 | 28,150 Direct | -6.94% | Disposed | -2.9% (price as of 2026-10-05) |
| Aug. 12, 2021 | ANNX | A | 20,000 | · | · | 20,000 Direct | · | Acquired | (price as of 2026-10-05) |
| May 27, 2021 | PTGX | A | 18,000 | · | · | 18,000 Direct | · | Acquired | (price as of 2026-10-05) |
| Jan. 4, 2021 | ARWR | S | 3,750 | $76.08 | $285,300 | 30,250 Direct | -11.03% | Disposed | -18.0% (price as of 2026-10-05) |
| Jan. 1, 2021 | ARWR | A | 9,000 | · | · | 34,000 Direct | +36.00% | Acquired | (price as of 2026-10-05) |
| Dec. 10, 2020 | ARWR | S | 1,800 | $73.10 | $131,580 | 25,000 Direct | -6.72% | Disposed | -14.7% (price as of 2026-10-05) |
| Dec. 10, 2020 | ARWR | S | 1,200 | $68.50 | $82,200 | 26,800 Direct | -4.29% | Disposed | -9.0% (price as of 2026-10-05) |
| May 28, 2020 | PTGX | A | 15,000 | · | · | 15,000 Direct | · | Acquired | (price as of 2026-10-05) |
| May 11, 2020 | ARWR | S | 26,000 | $36.54 | $950,040 | 28,000 Direct | -48.15% | Disposed | 70.6% (price as of 2026-10-05) |
| Jan. 1, 2020 | ARWR | A | 7,500 | · | · | 54,000 Direct | +16.13% | Acquired | (price as of 2026-10-05) |
| June 7, 2019 | PTGX | A | 12,000 | · | · | 12,000 Direct | · | Acquired | (price as of 2026-10-05) |
| Jan. 11, 2019 | ARWR | S | 8,500 | $14.77 | $125,545 | 46,500 Direct | -15.45% | Disposed | 322.1% (price as of 2026-10-05) |
| Jan. 1, 2019 | ARWR | A | 30,000 | · | · | 55,000 Direct | +120.00% | Acquired | (price as of 2026-10-05) |
| May 29, 2018 | PTGX | A | 12,000 | · | · | 12,000 Direct | · | Acquired | (price as of 2026-10-05) |
| Jan. 1, 2018 | ARWR | A | 25,000 | · | · | 25,000 Direct | · | Acquired | (price as of 2026-10-05) |
| May 25, 2017 | PTGX | A | 12,000 | · | · | 12,000 Direct | · | Acquired | (price as of 2026-10-05) |
| Sept. 13, 2016 | PTGX | A | 24,000 | · | · | 24,000 Direct | · | Acquired | (price as of 2026-10-05) |
P = Open-market purchase · S = Sale · A = Grant/award · M = Option exercise · G = Gift · F = Tax withholding
Insider transactions are not a recommendation; sales are often driven by liquidity or tax reasons.
Derivative holdings (Form 4 Table II) Options, RSUs and convertible securities reported on Form 4 Table II.
| Date | Ticker | Security | Underlying | Exercise price | Expiration | Shares | A/D |
|---|---|---|---|---|---|---|---|
| June 23, 2026 | PTGX | Stock Option (right to buy) | Common Stock | $16.54 | May 27, 2030 | 9,000 | Disposed |
| June 11, 2026 | ANNX | Stock Option (Right to Buy) | Common Stock | $4.70 | June 11, 2036 | 65,000 | Acquired |
| June 10, 2026 | PTGX | Stock Option (right to buy) | Common Stock | $16.54 | May 27, 2030 | 6,000 | Disposed |
| June 10, 2026 | PTGX | Stock Option (right to buy) | Common Stock | $11.80 | June 6, 2029 | 3,000 | Disposed |
| May 29, 2026 | PTGX | Stock Option (right to buy) | Common Stock | $11.80 | June 6, 2029 | 9,000 | Disposed |
| Feb. 6, 2026 | PTGX | Stock Option (right to buy) | Common Stock | $8.31 | May 25, 2032 | 20,000 | Disposed |
| Jan. 2, 2026 | PTGX | Stock Option (right to buy) | Common Stock | $87.18 | Jan. 2, 2036 | 3,762 | Acquired |
| Oct. 10, 2025 | PTGX | Stock Option (right to buy) | Common Stock | $6.98 | May 28, 2028 | 12,000 | Disposed |
| June 5, 2025 | ANNX | Stock Option (Right to Buy) | Common Stock | $2.55 | June 5, 2035 | 55,000 | Acquired |
| Jan. 2, 2025 | PTGX | Stock Option (right to buy) | Common Stock | $38.98 | Jan. 2, 2035 | 6,584 | Acquired |
| Sept. 10, 2024 | PTGX | Stock Option (right to buy) | Common Stock | $12.88 | Sept. 13, 2026 | 8,000 | Disposed |
| July 24, 2024 | PTGX | Stock Option (right to buy) | Common Stock | $12.88 | Sept. 13, 2026 | 8,000 | Disposed |
| June 7, 2024 | PTGX | Stock Option (right to buy) | Common Stock | $12.88 | Sept. 13, 2026 | 8,000 | Disposed |
| June 5, 2024 | ANNX | Stock Option (Right to Buy) | Common Stock | $6.79 | June 5, 2034 | 44,000 | Acquired |
| March 1, 2024 | PTGX | Stock Option (right to buy) | Common Stock | $6.09 | July 16, 2026 | 12,975 | Disposed |
| Jan. 2, 2024 | PTGX | Stock Option (right to buy) | Common Stock | $23.42 | Jan. 2, 2034 | 25,700 | Acquired |
| June 8, 2023 | ANNX | Stock Option (Right to Buy) | Common Stock | $2.88 | June 8, 2033 | 24,000 | Acquired |
| Jan. 16, 2023 | PTGX | Stock Option (right to buy) | Common Stock | $12.17 | Jan. 15, 2033 | 30,000 | Acquired |
| Jan. 10, 2023 | ARWR | Common Stock | Common Stock | $33.03 | Jan. 10, 2033 | 4,593 | Acquired |
| June 9, 2022 | ANNX | Stock Option (Right to Buy) | Common Stock | $3.84 | June 9, 2032 | 24,000 | Acquired |
| May 26, 2022 | PTGX | Stock Option (right to buy) | Common Stock | $8.31 | May 26, 2032 | 20,000 | Acquired |
| May 3, 2022 | PTGX | Stock Option (right to buy) | Common Stock | $8.59 | May 25, 2027 | 12,000 | Disposed |
| Aug. 12, 2021 | ANNX | Stock Option (Right to Buy) | Common Stock | $19.73 | Aug. 12, 2031 | 20,000 | Acquired |
| May 27, 2021 | PTGX | Stock Option (right to buy) | Common Stock | $35.23 | May 26, 2031 | 18,000 | Acquired |
| May 28, 2020 | PTGX | Stock Option (right to buy) | Common Stock | $16.54 | May 27, 2030 | 15,000 | Acquired |
| June 7, 2019 | PTGX | Stock Option (right to buy) | Common Stock | $11.80 | June 6, 2029 | 12,000 | Acquired |
| May 29, 2018 | PTGX | Stock Option (right to buy) | Common Stock | $6.98 | May 28, 2028 | 12,000 | Acquired |
| May 25, 2017 | PTGX | Stock Option (right to buy) | Common Stock | $8.59 | May 25, 2027 | 12,000 | Acquired |
| Sept. 13, 2016 | PTGX | Stock Option (right to buy) | Common Stock | $12.88 | Sept. 13, 2026 | 24,000 | Acquired |
Exercise/conversion price is blank when not applicable (e.g. RSUs).
Initial ownership (Form 3) 1 holding
Securities held when first becoming an insider, per SEC Form 3.
| Date | Ticker | Security | Shares | Ownership |
|---|---|---|---|---|
| Aug. 10, 2016 | PTGX | Stock Option (right to buy) | 12,975 | Direct |