ACAD ACADIA Pharmaceuticals Inc. - Common Stock
$29,17
Precio · Ago 18, 2026
Fundamentales a fecha de Ago 5, 2026
Rango 52S
$20–$30
93% of range
Calificación del Analista
BUY
27 analysts
Precio Objetivo
$34
+16% upside
P/E (TTM)
12.7
ROE
38.1%
Margen de Beneficio Neto
36.5%
Acerca de ACADIA Pharmaceuticals Inc. - Common Stock Descripción general de la empresa de Wikipedia
Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, California.
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Acadia Pharmaceuticals Inc. is a biopharmaceutical company headquartered in Del Mar, California.
Product development
Nuplazid, a drug developed by Acadia in the late 1990s, "was designed to stimulate a subset of the brain’s serotonin receptors, or the proteins that govern memory, cognition and learning." On April 29, 2016, the FDA approved Acadia's drug, Nuplazid, for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis. Nuplazid is the trade name for Acadia's proprietary molecule, pimavanserin, a selective serotonin inverse agonist preferentially targeting 5-HT2a receptors. Acadia had partnered with Biovail in the late-stage clinical testing of the drug, which showed trial failures as of 2009.
Acadia is running multiple Phase 2 and Phase 3 trials with pimavanserin in several central nervous system conditions: dementia-related psychosis, major depressive disorder, schizophrenia inadequate response, and schizophrenia negative symptoms.
As of 1997, Acadia was among several companies that licensed compounds from Genzyme's small-molecule compound library.
In 2023, the FDA approved trofinetide (marketed as Daybue) for use in Rett syndrome.
History
Acadia started in 1993 as Receptor Technologies, based in Winooski, Vermont. In 1997, the company relocated all operations and management from Vermont to San Diego, California, as a strategic move to garner partnerships with other biotechnology companies. However, the company also had an office in Denmark, in which it received a crucial part of its early investments from BankInvest, under managing director Florian Schönharting, Kommunernes Pensionsforsikring A/S and Dansk Kapitalanlæg Aktieselskab as well as private investor Lars Christiansen. At the time, the company had fifty employees, fourteen of whom were in the Denmark office. The focus of the company in its early years was on genetic screens for receptors, aiming to accelerate early stage drug discovery.
The company planned to conduct an initial public offering (IPO) consisting of 31.6% of the company in 2001, with the intention of raising US$64 million and listing on the NASDAQ exchange under the symbol ACAD. At the time, Acadia and Allergan were collaborating on development of a treatment for glaucoma, and Allergan would retain a 6.3% ownership stake in Acadia after the IPO. However, the company's IPO, which ultimately took place in May 2004, did not fare as well as expected and netted only US$35 million. At the time, the company had five drugs in development and was running two in human trials. The company had a subsequent round of stock offering in May 2007 which raised US$102 million.
In September 2020, Acadia Pharmaceuticals acquired clinical-stage biotechnology company CerSci Therapeutics.
Corporate governance
In 2001, the company's chief executive officer at the time, Leonard R. Borrmann, left Acadia to lead Maret Pharmaceuticals. He was succeeded by Uli Hacksell, who left Acadia to lead Cerecor at the beginning of 2016.
== References ==
Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗
ACAD Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$29.17
Capitalización Bursátil
$4.97B
P/E (TTM)
12.7
BPA (TTM)
$2.30
Ingresos (TTM)
$1.07B
Rendimiento div.
—
ROE
38.1%
Deuda/Capital
—
Rango 52S
$20 – $30
ACAD Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
$1.07B
2016-12-31
→
2025-12-31
BPA
$2.30
2020-12-31
→
2025-12-31
Flujo de caja libre
$105M
2016-12-31
→
2025-12-31
Márgenes
36.5%
2016-12-31
→
2023-12-31
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
ACAD
Mediana de Pares
P/E (TTM)
12.7
13.2
P/S (TTM) (P/V (TTM))
4.6
55.3
P/B (P/C)
4.0
3.5
Price / FCF (Precio / FCF)
47.2
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
ACAD
Mediana de Pares
Operating Margin (Margen Operativo)
9.8%
—
Net Profit Margin (Margen de Beneficio Neto)
36.5%
-151.2%
ROA
28.4%
-42.2%
ROE
38.1%
-52.8%
ROIC
24.0%
—
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
ACAD
Mediana de Pares
Current Ratio (Ratio corriente)
3.8
10.3
Quick Ratio (Ratio Rápido)
1.1
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
ACAD
Mediana de Pares
Revenue YoY (Ingresos interanuales)
11.9%
—
Revenue CAGR 3Y (Ingresos CAGR 3A)
27.5%
—
Revenue CAGR 5Y (Ingresos CAGR 5A)
19.4%
—
EPS YoY (EPS interanual)
69.1%
—
Net Income YoY (Beneficio Neto interanual)
72.7%
—
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
ACAD
Mediana de Pares
ACAD Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
27 analistas
- Compra fuerte 7 25,9%
- Compra 14 51,9%
- Mantener 5 18,5%
- Venta 1 3,7%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
20 analistas · 2026-08-18
Mediana
$36.00
Ahora
$29.17
Mín
$17.00
Máx
$49.00
Objetivo mediano
$36.00
+23,4%
Objetivo medio
$33.85
+16,0%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.30%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $0.18 | $0.06 | 0.12% |
| 31 de marzo de 2026 | $0.02 | $0.06 | -0.04% |
| 31 de diciembre de 2025 | $1.60 | $0.14 | 1.5% |
| 30 de septiembre de 2025 | $0.42 | $0.15 | 0.27% |
| 30 de junio de 2025 | $0.16 | $0.14 | 0.02% |
| 31 de marzo de 2025 | $0.11 | $0.11 | -0.00% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| ACAD | $4.55B | 11.6 | 11.9% | 36.5% | 38.1% | — |
| DNTH | $1.78B | -9.8 | -67.3% | -7973.3% | -40.8% | — |
| CAI | $7.62B | -8.4 | 97.0% | -8.4% | -13.2% | — |
| PTCT | $6.19B | 9.8 | 114.5% | 39.4% | -331.5% | — |
| TVTX | $3.47B | -131.8 | 110.5% | -5.2% | -34.6% | — |
| DYN | $3.23B | -5.6 | — | — | -57.8% | — |
| CELC | $4.81B | -26.3 | — | — | -244.3% | — |
| RLAY | $1.47B | -5.3 | 53.4% | -1800.6% | -44.9% | — |
| PBLS | — | — | — | — | — | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1.07B | $958M | $726M | $517M | $484M | $442M | $339M | $224M | $125M | $17M | $61.0K | $120.0K | |
| Cost of Revenue | $89M | $82M | $42M | $10M | $19M | $10M | $11M | $12M | $9M | $3M | · | · | |
| Gross Profit | · | · | $685M | $507M | $473M | $432M | $328M | $211M | $116M | $14M | · | · | |
| R&D Expense | $329M | $303M | $352M | $362M | $239M | $319M | $240M | $187M | $149M | $99M | $74M | $61M | |
| SG&A Expense | $549M | $488M | $407M | $369M | $396M | $389M | $326M | $266M | $255M | $186M | $88M | $33M | |
| Operating Expenses | $967M | $727M | $800M | $741M | $655M | $728M | $586M | $471M | $417M | $290M | $165M | $93M | |
| Operating Income | $105M | $231M | $-73M | $-224M | $-170M | $-287M | $-247M | $-247M | $-292M | $-273M | $-165M | $-93M | |
| Other Non-op | $2M | $2M | $5M | $4M | $2M | $-997.0K | $997.0K | $-2M | · | · | · | · | |
| Pretax Income | $139M | $258M | $-51M | $-213M | $-168M | $-281M | $-234M | $-244M | $-288M | $-270M | $-164M | $-92M | |
| Income Tax | $-252M | $32M | $10M | $3M | $351.0K | $611.0K | $876.0K | $1M | $1M | $1M | $330.0K | $0 | |
| Net Income | $391M | $226M | $-61M | $-216M | $-168M | $-282M | $-235M | $-245M | $-289M | $-271M | $-164M | $-92M | |
| EPS (Basic) | $2.32 | $1.37 | $-0.37 | $-1.34 | $-1.05 | $-1.79 | · | · | · | · | · | · | |
| EPS (Diluted) | $2.30 | $1.36 | $-0.37 | $-1.34 | $-1.05 | $-1.79 | · | · | · | · | · | · | |
| Shares (Basic) | 168,356,000 | 165,717,000 | 163,819,000 | 161,683,000 | 160,493 | 157,331 | · | · | · | · | · | · | |
| Shares (Diluted) | 169,919,000 | 166,362,000 | 163,819,000 | 161,683,000 | 160,493 | 157,331 | · | · | · | · | · | · | |
| EBITDA | $105M | $231M | $-73M | $-224M | $-170M | $-287M | $-247M | $-247M | $-292M | $-273M | $-165M | $-93M |
Balance general 25
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $178M | $320M | $189M | $115M | $147M | $326M | $190M | $135M | $69M | $164M | $102M | $62M | |
| Receivables | $121M | $99M | $98M | $62M | $64M | $48M | $36M | $26M | $17M | $6M | · | · | |
| Inventory | $111M | $92M | $40M | $12M | $14M | $10M | $6M | $4M | $5M | $4M | · | · | |
| Prepaid Expense | $60M | $56M | $39M | $21M | $24M | $26M | $19M | $21M | $8M | $8M | $2M | $1M | |
| Current Assets | $1.06B | $938M | $616M | $508M | $618M | $718M | $760M | $526M | $373M | $548M | $219M | $325M | |
| PP&E (Net) | $8M | $4M | $5M | $6M | $8M | $9M | $3M | $3M | $3M | $3M | $2M | $553.0K | |
| PP&E (Gross) | $17M | $14M | $14M | $14M | $14M | $13M | $9M | $8M | $7M | $6M | $5M | $3M | |
| Accum. Depreciation | $9M | $10M | $10M | $8M | $6M | $4M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Intangibles | $109M | $120M | $65M | $0 | $0 | $1M | $3M | $4M | $6M | $7M | · | · | |
| Other Non-current Assets | $4M | $359.0K | $476.0K | $8M | $4M | $2M | $3M | $2M | $354.0K | $785.0K | $329.0K | $287.0K | |
| Total Assets | $1.56B | $1.19B | $749M | $588M | $700M | $783M | $783M | $540M | $385M | $561M | $222M | $325M | |
| Accounts Payable | $11M | $16M | $18M | $13M | $7M | $8M | $7M | $3M | $9M | $4M | $2M | $2M | |
| Accrued Liabilities | $266M | $379M | $237M | $113M | $89M | $97M | $68M | $56M | $40M | $36M | $20M | $14M | |
| Current Liabilities | $277M | $395M | $254M | $126M | $96M | $106M | $75M | $60M | $49M | $43M | $22M | $16M | |
| Capital Leases | $41M | $42M | $48M | $53M | $56M | $44M | $6M | · | · | · | · | · | |
| Deferred Tax | $11M | $11M | $12M | $13M | $14M | $13M | $3M | · | · | · | · | · | |
| Other Non-current Liabilities | $19M | $18M | $15M | $9M | $7M | $5M | $3M | $2M | · | · | · | · | |
| Total Liabilities | $337M | $455M | $317M | $187M | $159M | $156M | $84M | $61M | $49M | $43M | $22M | $16M | |
| Common Stock | $16.0K | $16.0K | $16.0K | $16.0K | $16.0K | $16.0K | $15.0K | $14.0K | $12.0K | $12.0K | $10.0K | $10.0K | |
| Paid-in Capital | · | · | · | · | · | · | · | · | · | $1.45B | $862M | $808M | |
| Retained Earnings | $-1.81B | $-2.20B | $-2.43B | $-2.37B | $-2.15B | $-1.99B | $-1.70B | $-1.47B | $-1.22B | $-934M | $-663M | $-498M | |
| AOCI | $1M | $292.0K | $24.0K | $-975.0K | $-192.0K | $36.0K | $297.0K | $-372.0K | $-399.0K | $106.0K | $11.0K | $-9.0K | |
| Stockholders' Equity | $1.23B | $733M | $432M | $400M | $541M | $627M | $699M | $479M | $335M | $518M | $200M | $309M | |
| Liabilities + Equity | $1.56B | $1.19B | $749M | $588M | $700M | $783M | $783M | $540M | $385M | $561M | $222M | $325M | |
| Shares Outstanding | 170,309,376 | 166,708,856 | 164,650,219 | 162,064,872 | 161,012,695 | 159,637,771 | 155,275,300 | 143,853,597 | 124,410,552 | 121,367,169 | 101,938,702 | 100,047,331 |
Flujo de Efectivo 13
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | · | · | · | · | · | · | · | · | · | · | · | $206.0K | |
| Stock-based Comp | $52M | $67M | $66M | $68M | $64M | $84M | $82M | $82M | $76M | $55M | $40M | $16M | |
| Deferred Tax | $-250M | $0 | $0 | $3M | $351.0K | · | · | · | · | · | · | · | |
| Amort. of Intangibles | $11M | $15M | $4M | $0 | $1M | $1M | $1M | $1M | $1M | $985.0K | $0 | $0 | |
| Operating Cash Flow | $110M | $158M | $17M | $-114M | $-126M | $-136M | $-151M | $-167M | $-218M | $-208M | $-122M | $-66M | |
| CapEx | $5M | $523.0K | $50.0K | $0 | $1M | $8M | $1M | $2M | $812.0K | $2M | $2M | $180.0K | |
| Investing Cash Flow | $-303M | $-31M | $32M | $73M | $-71M | $193M | $-166M | $-71M | $92M | $-262M | · | · | |
| Stock Issued | $50M | $7M | $25M | $8M | $18M | $81M | $372M | $307M | $31M | $519M | $15M | $204M | |
| Net Stock Activity | $50M | $7M | $25M | $8M | $18M | $81M | $372M | $307M | $31M | $519M | $15M | $204M | |
| Financing Cash Flow | $50M | $7M | $25M | $8M | $18M | $81M | $372M | $307M | $31M | $534M | · | · | |
| Net Change in Cash | $-143M | $134M | $74M | $-33M | $-179M | $137M | $55M | $68M | $-94M | $63M | $40M | $50M | |
| Taxes Paid | $25M | $20M | $6M | $2M | $1M | $1M | $2M | $1M | $1M | $-365.0K | $415.0K | · | |
| Free Cash Flow | $105M | $157M | $17M | $-114M | $-127M | $-144M | $-152M | $-170M | $-219M | $-212M | $-124M | $-67M |
Rentabilidad 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | · | · | 94.3% | 98.0% | 97.8% | 97.7% | 96.7% | 94.5% | 92.7% | 82.2% | · | · | |
| Operating Margin | 9.8% | 24.1% | -10.1% | -43.2% | -35.2% | -64.9% | -72.7% | -110.6% | -234.1% | -1574.1% | -269855.7% | -77691.7% | |
| Net Margin | 36.5% | 23.6% | -8.4% | -41.8% | -34.7% | -63.7% | -69.4% | -109.6% | -231.7% | -1565.9% | -269578.7% | -77062.5% | |
| Pretax Margin | 13.0% | 26.9% | -7.0% | -41.3% | -34.6% | -63.6% | -69.1% | -109.0% | -230.8% | -1558.2% | -269037.7% | · | |
| EBITDA Margin | 9.8% | 24.1% | -10.1% | -43.2% | -35.2% | -64.9% | -72.7% | -110.6% | -234.1% | -1574.1% | -269855.7% | -77691.7% | |
| ROA | 28.4% | 23.4% | -9.2% | -33.5% | -22.6% | -36.0% | -35.5% | -53.0% | -61.2% | -69.3% | -60.1% | -35.9% | |
| ROE | 38.1% | 34.6% | -15.4% | -52.3% | -30.3% | -43.9% | -33.9% | -69.8% | -67.8% | -75.6% | -64.6% | -37.6% | |
| ROIC | 24.0% | 27.6% | -20.4% | -56.5% | -31.6% | -45.8% | -35.4% | -51.9% | -87.5% | -52.9% | -82.6% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.8 | 2.4 | 2.4 | 4.0 | 6.4 | 6.8 | 10.2 | 8.8 | 7.6 | 12.9 | 10.0 | 20.5 | |
| Quick Ratio | 1.1 | 1.1 | 1.1 | 1.4 | 2.2 | 3.5 | 3.0 | 2.7 | 1.8 | 4.0 | 4.7 | 3.9 |
Eficiencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.8 | 1.0 | 1.1 | 0.8 | 0.7 | 0.6 | 0.5 | 0.5 | 0.3 | 0.0 | 0.0 | 0.0 | |
| Inventory Turnover | 0.9 | 1.2 | 1.6 | 0.8 | 0.9 | 1.3 | 2.2 | · | 1.9 | 1.5 | · | · | |
| Receivables Turnover | 9.7 | 9.7 | 9.1 | 8.2 | 8.6 | 10.5 | 11.0 | 10.3 | 10.7 | 5.9 | · | · |
Tasas de Crecimiento 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 11.9% | 31.9% | 40.5% | 6.8% | 9.6% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | 27.5% | 25.5% | 18.0% | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 19.4% | · | · | · | · | · | · | · | · | · | · | · | |
| EPS YoY | 69.1% | · | · | · | · | · | · | · | · | · | · | · | |
| Net Income YoY | 72.7% | · | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $1.07B | $958M | $726M | $517M | $484M | $442M | $339M | $224M | $125M | $17M | $61.0K | $120.0K | |
| Net Income TTM | $391M | $226M | $-61M | $-216M | $-168M | $-282M | $-235M | $-245M | $-289M | $-271M | $-164M | $-92M | |
| Market Cap | $4.55B | $3.06B | $5.16B | $2.58B | $3.76B | $8.53B | $6.64B | $2.33B | $3.75B | $3.50B | $3.63B | $3.18B | |
| P/E | 11.6 | 13.5 | -84.6 | -11.9 | -22.2 | -29.9 | · | · | · | · | · | · | |
| P/S | 4.2 | 3.2 | 7.1 | 5.0 | 7.8 | 19.3 | 19.6 | 10.4 | 30.0 | 202.0 | 59575.7 | 26470.9 | |
| P/B | 3.7 | 4.2 | 11.9 | 6.4 | 6.9 | 13.6 | 9.5 | 4.9 | 11.2 | 6.8 | 18.2 | 10.3 | |
| P / Tangible Book | 4.1 | 5.0 | 14.1 | 6.4 | 6.9 | 13.6 | · | · | · | · | · | · | |
| P / Cash Flow | 41.4 | 19.4 | 308.7 | -22.6 | -29.9 | -62.7 | -44.0 | -13.9 | -17.2 | -16.6 | -29.8 | -47.8 | |
| P / FCF | 43.3 | 19.5 | 309.6 | -22.6 | -29.6 | -59.4 | -43.6 | -13.7 | -17.1 | -16.5 | -29.3 | -47.7 | |
| Earnings Yield | 8.6% | 7.4% | -1.2% | -8.4% | -4.5% | -3.4% | · | · | · | · | · | · |
Estado de resultados 16
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $308M | $268M | $284M | $279M | $265M | $244M | $260M | $250M | $242M | $206M | $231M | $212M | $165M | $118M | $136M | $131M | |
| Cost of Revenue | $28M | $25M | $26M | $22M | $21M | $20M | $22M | $19M | $18M | $23M | $18M | $15M | $7M | $2M | $2M | $2M | |
| Gross Profit | · | · | · | · | · | · | · | · | · | · | $213M | $197M | $158M | $117M | $134M | $129M | |
| R&D Expense | $82M | $77M | $85M | $88M | $78M | $78M | $101M | $67M | $76M | $60M | $67M | $157M | $59M | $69M | $76M | $81M | |
| SG&A Expense | $160M | $171M | $156M | $133M | $134M | $126M | $130M | $133M | $117M | $108M | $111M | $98M | $96M | $101M | $104M | $78M | |
| Operating Expenses | $270M | $273M | $267M | $243M | $232M | $225M | $106M | $219M | $212M | $191M | $196M | $269M | $162M | $172M | $183M | $162M | |
| Operating Income | $38M | $-5M | $17M | $36M | $32M | $19M | $154M | $32M | $30M | $15M | $35M | $-58M | $3M | $-54M | $-46M | $-31M | |
| Other Non-op | $647.0K | $542.0K | $596.0K | $593.0K | $594.0K | $588.0K | $575.0K | $576.0K | $386.0K | $286.0K | $0 | $2M | $-1M | $5M | $2M | $2M | |
| Pretax Income | $46M | $4M | $26M | $45M | $40M | $28M | $161M | $39M | $37M | $21M | $40M | $-52M | $6M | $-45M | $-41M | $-26M | |
| Income Tax | $15M | $344.0K | $-247M | $-27M | $14M | $9M | $17M | $6M | $4M | $4M | $-6M | $13M | $5M | $-2M | $835.0K | $768.0K | |
| Net Income | $32M | $4M | $274M | $72M | $27M | $19M | $144M | $33M | $33M | $17M | $46M | $-65M | $1M | $-43M | $-42M | $-27M | |
| EPS (Basic) | $0.18 | $0.02 | $1.62 | $0.43 | $0.16 | $0.11 | $0.87 | $0.20 | $0.20 | $0.10 | $0.29 | $-0.40 | $0.01 | $-0.27 | $-0.26 | $-0.17 | |
| EPS (Diluted) | $0.18 | $0.02 | $1.61 | $0.42 | $0.16 | $0.11 | $0.86 | $0.20 | $0.20 | $0.10 | $0.29 | $-0.40 | $0.01 | $-0.27 | $-0.26 | $-0.17 | |
| Shares (Basic) | 171,603,000 | 170,517,000 | -335,115,000 | 168,836,000 | 167,827,000 | 166,808,000 | -330,606,000 | 165,974,000 | 165,551,000 | 164,798,000 | -326,136,000 | 164,234,000 | 163,458,000 | 162,263,000 | 128,494 | 161,852 | |
| Shares (Diluted) | 172,851,000 | 172,706,000 | -337,080,000 | 170,650,000 | 168,681,000 | 167,668,000 | -332,613,000 | 166,178,000 | 166,174,000 | 166,623,000 | -327,724,000 | 164,234,000 | 165,046,000 | 162,263,000 | 128,494 | 161,852 | |
| EBITDA | $38M | $-5M | · | $36M | $32M | $19M | · | $32M | $30M | $15M | · | $-58M | $3M | $-54M | · | $-31M |
Balance general 24
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $385M | $282M | $178M | $258M | $254M | $218M | $320M | $155M | $177M | $205M | $189M | $98M | $108M | $291M | $115M | $155M | |
| Receivables | $151M | $135M | $121M | $116M | $108M | $106M | $99M | $98M | $104M | $95M | · | $93M | $82M | $66M | · | $56M | |
| Inventory | $109M | $112M | $111M | $106M | $111M | $103M | $92M | $87M | $86M | $67M | · | $25M | $14M | $11M | · | $12M | |
| Prepaid Expense | $69M | $65M | $60M | $61M | $53M | $53M | $56M | $52M | $46M | $43M | · | $38M | $24M | $24M | · | $23M | |
| Current Assets | $1.22B | $1.10B | $1.06B | $1.08B | $961M | $871M | $938M | $788M | $729M | $675M | · | $499M | $493M | $503M | · | $522M | |
| PP&E (Net) | $17M | $15M | $8M | $4M | $4M | $3M | $4M | $4M | $4M | $4M | · | $5M | $5M | $6M | · | $7M | |
| PP&E (Gross) | · | · | $17M | · | · | · | $14M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $9M | · | · | · | $10M | · | · | · | · | · | · | · | · | · | |
| Intangibles | $103M | $106M | $109M | $112M | $114M | $117M | $120M | $106M | $108M | $110M | · | $67M | $68M | $70M | · | · | |
| Other Non-current Assets | $4M | $4M | $4M | $3M | $2M | $1M | $359.0K | $359.0K | $476.0K | $476.0K | · | $475.0K | $11M | $12M | · | $6M | |
| Total Assets | $1.74B | $1.61B | $1.56B | $1.33B | $1.23B | $1.13B | $1.19B | $977M | $914M | $855M | · | $633M | $643M | $655M | · | $602M | |
| Accounts Payable | $45M | $12M | $11M | $22M | $20M | $18M | $16M | $19M | $20M | $19M | · | $12M | $19M | $17M | · | $10M | |
| Accrued Liabilities | $317M | $293M | $266M | $335M | $310M | $284M | $379M | $325M | $318M | $311M | · | $197M | $169M | $207M | · | $107M | |
| Current Liabilities | $361M | $306M | $277M | $357M | $330M | $303M | $395M | $344M | $338M | $331M | · | $210M | $188M | $224M | · | $117M | |
| Capital Leases | $60M | $39M | $41M | $43M | $45M | $45M | $42M | $40M | $47M | $49M | · | $48M | $50M | $51M | · | $54M | |
| Deferred Tax | · | · | $11M | · | · | · | $11M | · | · | · | · | · | · | · | · | · | |
| Other Non-current Liabilities | $15M | $13M | $19M | $14M | $29M | $20M | $18M | $15M | $12M | $11M | · | $13M | $9M | $5M | · | $6M | |
| Total Liabilities | $436M | $357M | $337M | $413M | $403M | $367M | $455M | $400M | $397M | $391M | · | $270M | $247M | $281M | · | $177M | |
| Common Stock | $16.0K | $16.0K | $16.0K | $16.0K | $16.0K | $16.0K | $16.0K | $16.0K | $16.0K | $16.0K | · | $16.0K | $16.0K | $16.0K | · | $16.0K | |
| Retained Earnings | $-1.78B | $-1.81B | $-1.81B | $-2.09B | $-2.16B | $-2.19B | $-2.20B | $-2.35B | $-2.38B | $-2.41B | · | $-2.48B | $-2.41B | $-2.41B | · | $-2.33B | |
| AOCI | $-958.0K | $-563.0K | $1M | $989.0K | $406.0K | $437.0K | $292.0K | $858.0K | $-339.0K | $-229.0K | · | $-319.0K | $-535.0K | $-220.0K | · | $-1M | |
| Stockholders' Equity | $1.31B | $1.25B | $1.23B | $917M | $822M | $765M | $733M | $577M | $517M | $464M | $432M | $362M | $396M | $374M | $400M | $426M | |
| Liabilities + Equity | $1.74B | $1.61B | $1.56B | $1.33B | $1.23B | $1.13B | $1.19B | $977M | $914M | $855M | · | $633M | $643M | $655M | · | $602M | |
| Shares Outstanding | 172,132,442 | 171,086,205 | 170,309,376 | 169,146,043 | 168,607,881 | 167,116,045 | 166,708,856 | 166,351,715 | 165,853,301 | 164,959,736 | · | 163,968,949 | 163,355,787 | 162,384,178 | · | 161,871,806 |
Flujo de Efectivo 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $17M | $15M | $13M | $13M | $14M | $11M | $10M | $26M | $16M | $15M | $18M | $19M | $15M | $15M | $14M | $18M | |
| Amort. of Intangibles | $3M | $3M | $3M | $3M | $3M | $3M | $5M | $2M | $2M | $5M | $1M | $1M | $1M | $0 | $0 | $0 | |
| Operating Cash Flow | $101M | $34M | $-49M | $74M | $64M | $20M | $40M | $63M | $25M | $29M | $85M | $-59M | $8M | $-18M | $-24M | $-727.0K | |
| CapEx | $5M | $5M | $4M | $388.0K | $297.0K | $0 | $453.0K | $70.0K | · | · | $0 | · | · | · | $0 | $0 | |
| Investing Cash Flow | $-9M | $66M | $-56M | $-79M | $-43M | $-124M | $122M | $-82M | $-56M | $-14M | $-347.0K | $34M | $-194M | $193M | $-18M | $15M | |
| Stock Issued | $10M | $4M | $23M | $9M | $16M | $2M | $2M | $268.0K | $4M | $1M | $5M | $13M | $5M | $1M | $2M | $287.0K | |
| Net Stock Activity | · | $4M | · | · | · | $2M | · | · | · | $1M | · | · | · | $1M | · | · | |
| Financing Cash Flow | $10M | $4M | $23M | $9M | $16M | $2M | $2M | $268.0K | $4M | $1M | $5M | $13M | $5M | $1M | $2M | $287.0K | |
| Net Change in Cash | $103M | $105M | $-82M | $4M | $37M | $-102M | $164M | $-19M | $-28M | $16M | $90M | $-12M | $-181M | $176M | $-40M | $15M | |
| Free Cash Flow | · | $29M | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | 12.3% | -1.7% | · | 12.8% | 12.2% | 7.9% | · | 12.6% | 12.6% | 7.4% | · | -27.3% | 1.8% | -45.2% | · | -23.6% | |
| Net Margin | 10.2% | 1.4% | · | 25.8% | 10.1% | 7.8% | · | 13.1% | 13.8% | 8.0% | · | -30.8% | 0.67% | -36.3% | · | -20.8% | |
| Pretax Margin | 15.1% | 1.5% | · | 16.0% | 15.2% | 11.4% | · | 15.5% | 15.4% | 10.2% | · | -24.6% | 3.8% | -37.9% | · | -20.2% | |
| EBITDA Margin | 12.3% | -1.7% | · | 12.8% | 12.2% | 7.9% | · | 12.6% | 12.6% | 7.4% | · | -27.3% | 1.8% | -45.2% | · | -23.6% | |
| ROA | 2.1% | 0.27% | · | 6.2% | 2.5% | 1.9% | · | 4.1% | 4.3% | 2.2% | · | -10.5% | 0.18% | -6.7% | · | -4.1% | |
| ROE | 3.0% | 0.36% | · | 9.6% | 4.0% | 3.1% | · | 7.0% | 7.3% | 4.0% | · | -16.6% | 0.27% | -10.5% | · | -5.5% | |
| ROIC | 2.0% | -0.34% | · | 6.3% | 2.6% | 1.7% | · | 4.6% | 5.3% | 2.6% | · | -19.9% | 0.13% | -13.7% | · | -7.5% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.4 | 3.6 | · | 3.0 | 2.9 | 2.9 | · | 2.3 | 2.2 | 2.0 | · | 2.4 | 2.6 | 2.2 | · | 4.5 | |
| Quick Ratio | 1.5 | 1.4 | · | 1.0 | 1.1 | 1.1 | · | 0.7 | 0.8 | 0.9 | · | 0.9 | 1.0 | 1.6 | · | 1.8 |
Eficiencia 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.2 | 0.2 | · | 0.2 | 0.2 | 0.2 | · | 0.3 | 0.3 | 0.3 | · | 0.3 | 0.3 | 0.2 | · | 0.2 | |
| Inventory Turnover | 0.3 | 0.2 | · | 0.2 | 0.2 | 0.2 | · | 0.3 | 0.4 | 0.6 | · | 0.8 | 0.6 | 0.1 | · | 0.2 | |
| Receivables Turnover | 2.4 | 2.2 | · | 2.6 | 2.5 | 2.4 | · | 2.6 | 2.6 | 2.6 | · | 2.9 | 2.2 | 1.8 | · | 2.2 |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $1.12B | $1.06B | · | $1.04B | $1.00B | $943M | · | $929M | $891M | $814M | · | $632M | $551M | $520M | · | $512M | |
| Net Income TTM | $134M | $121M | · | $150M | $112M | $102M | · | $129M | $31M | $-2M | · | $-149M | $-111M | $-146M | · | $-217M | |
| Market Cap | $4.35B | $3.81B | · | $3.61B | $3.64B | $2.78B | · | $2.56B | $2.70B | $3.05B | · | $3.42B | $3.91B | $3.06B | · | $2.65B | |
| P/E | 32.4 | 31.4 | · | 24.0 | 32.2 | 27.2 | · | 19.7 | 90.3 | -1849.0 | · | -22.7 | -34.7 | -20.7 | · | -12.1 | |
| P/S | 3.9 | 3.6 | · | 3.5 | 3.6 | 2.9 | · | 2.8 | 3.0 | 3.7 | · | 5.4 | 7.1 | 5.9 | · | 5.2 | |
| P/B | 3.3 | 3.1 | · | 3.9 | 4.4 | 3.6 | · | 4.4 | 5.2 | 6.6 | · | 9.4 | 9.9 | 8.2 | · | 6.2 | |
| P / Tangible Book | 3.6 | 3.3 | · | 4.5 | 5.1 | 4.3 | · | 5.4 | 6.6 | 8.6 | · | 11.6 | 11.9 | 10.0 | · | 6.2 | |
| P / Cash Flow | · | 112.1 | · | · | · | 136.6 | · | · | · | 104.9 | · | · | · | -170.4 | · | · | |
| P / FCF | · | 132.4 | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Earnings Yield | 3.1% | 3.2% | · | 4.2% | 3.1% | 3.7% | · | 5.1% | 1.1% | -0.05% | · | -4.4% | -2.9% | -4.8% | · | -8.2% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $1.07B | $958M | $726M | $517M | $484M |
| Margen Bruto % | — | — | 94.3% | 98.0% | 97.8% |
| Margen Operativo % | 9.8% | 24.1% | -10.1% | -43.2% | -35.2% |
| Beneficio neto | $391M | $226M | $-61M | $-216M | $-168M |
| EPS Diluido | $2.30 | $1.36 | $-0.37 | $-1.34 | $-1.05 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 3.8 | 2.4 | 2.4 | 4.0 | 6.4 |
| Ratio Rápido | 1.1 | 1.1 | 1.1 | 1.4 | 2.2 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $105M | $157M | $17M | $-114M | $-127M |
Últimas noticias Noticias recientes que mencionan a esta empresa
Señales de trading Señales recientes de compra/venta con precio de entrada y ratio riesgo/recompensa
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Propietarios institucionales (13F) 387 declarantes · $3.2B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 56 (+10 vs trimestre anterior) | 37 (+10 vs trimestre anterior) | 136 (+11 vs trimestre anterior) | 100 (-13 vs trimestre anterior) | +17.3M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | $1 085 696 471 | 42 912 904 | 33,44% | Acciones |
| STATE STREET CORP | $229 628 164 | 9 076 212 | 7,07% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $223 612 785 | 8 838 450 | 6,89% | Acciones |
| RTW INVESTMENTS, LP | $180 756 457 | 7 144 524 | 5,57% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $145 822 875 | 5 763 750 | 4,49% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $88 971 384 | 3 516 656 | 2,74% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $73 088 127 | 2 888 204 | 2,25% | Acciones |
| Qube Research & Technologies Ltd | $61 899 233 | 2 446 610 | 1,91% | Acciones |
| Point72 Asset Management, L.P. | $61 559 150 | 2 433 168 | 1,90% | Acciones |
| CITADEL ADVISORS LLC | $53 414 195 | 2 111 233 | 1,65% | Acciones |
| Pictet Asset Management Holding SA | $50 146 450 | 1 983 198 | 1,54% | Acciones |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $49 826 959 | 1 969 445 | 1,53% | Acciones |
| MARSHALL WACE, LLP | $44 649 289 | 1 764 794 | 1,38% | Acciones |
| BRAIDWELL LP | $41 653 895 | 1 646 399 | 1,28% | Acciones |
| NORGES BANK | $41 069 692 | 1 623 308 | 1,26% | Acciones |
| Frazier Life Sciences Management, L.P. | $36 386 409 | 1 438 198 | 1,12% | Acciones |
| Artisan Partners Limited Partnership | $33 525 890 | 1 325 134 | 1,03% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $32 449 679 | 1 282 596 | 1,00% | Acciones |
| GOLDMAN SACHS GROUP INC | $32 070 584 | 1 267 612 | 0,99% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $30 520 301 | 1 206 336 | 0,94% | Acciones |
| D. E. Shaw & Co., Inc. | $28 330 257 | 1 119 773 | 0,87% | Acciones |
| Allspring Global Investments Holdings, LLC | $26 143 513 | 1 037 441 | 0,81% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $23 452 898 | 926 992 | 0,72% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $23 082 961 | 912 370 | 0,71% | Acciones |
| BANK OF AMERICA CORP /DE/ | $21 702 062 | 857 789 | 0,67% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $17 985 922 | 710 906 | 0,55% | Acciones |
| Fisher Asset Management, LLC | $17 690 535 | 699 230 | 0,54% | Acciones |
| Allianz Asset Management GmbH | $15 730 341 | 706 664 | 0,48% | Acciones |
| RICE HALL JAMES & ASSOCIATES, LLC | $15 657 841 | 618 887 | 0,48% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $14 925 077 | 589 924 | 0,46% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $14 771 456 | 583 852 | 0,45% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $12 903 000 | 510 000 | 0,40% | Acciones |
| Hudson Bay Capital Management LP | $11 764 500 | 465 000 | 0,36% | Acciones |
| GLENMEDE TRUST CO NA | $11 656 544 | 460 733 | 0,36% | Acciones |
| JUPITER ASSET MANAGEMENT LTD | $11 599 190 | 458 466 | 0,36% | Acciones |
| Public Sector Pension Investment Board | $11 014 988 | 435 375 | 0,34% | Acciones |
| MACKENZIE FINANCIAL CORP | $10 646 872 | 420 825 | 0,33% | Acciones |
| Ishara Investments LP | $10 373 000 | 410 000 | 0,32% | Acciones |
| TWO SIGMA ADVISERS, LP | $9 888 042 | 370 200 | 0,30% | Acciones |
| Balyasny Asset Management L.P. | $9 817 007 | 388 024 | 0,30% | Acciones |
| BlackRock, Inc. | $9 281 482 | 366 857 | 0,29% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $9 020 310 | 356 534 | 0,28% | Acciones |
| AMERIPRISE FINANCIAL INC | $8 039 177 | 317 754 | 0,25% | Acciones |
| PRUDENTIAL FINANCIAL INC | $7 985 313 | 315 625 | 0,25% | Acciones |
| Alyeska Investment Group, L.P. | $7 850 261 | 310 287 | 0,24% | Acciones |
| RHUMBLINE ADVISERS | $7 663 389 | 302 902 | 0,24% | Acciones |
| Schonfeld Strategic Advisors LLC | $7 189 171 | 284 157 | 0,22% | Acciones |
| Edgestream Partners, L.P. | $7 167 515 | 283 301 | 0,22% | Acciones |
| Logos Global Management LP | $6 325 000 | 250 000 | 0,19% | Acciones |
| LAZARD ASSET MANAGEMENT LLC | $6 263 496 | 247 569 | 0,19% | Acciones |
| FMR LLC | $6 052 317 | 239 222 | 0,19% | Acciones |
| Swiss National Bank | $5 841 871 | 230 904 | 0,18% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $5 432 213 | 214 712 | 0,17% | Acciones |
| ALPS ADVISORS INC | $4 985 340 | 197 049 | 0,15% | Acciones |
| ENVESTNET ASSET MANAGEMENT INC | $4 926 239 | 194 713 | 0,15% | Acciones |
| Legal & General Group Plc | $4 918 245 | 194 397 | 0,15% | Acciones |
| FIRST TRUST ADVISORS LP | $4 664 965 | 184 386 | 0,14% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $4 364 807 | 172 522 | 0,13% | Acciones |
| Birchview Capital, LP | $4 326 300 | 171 000 | 0,13% | Acciones |
| MARTINGALE ASSET MANAGEMENT L P | $4 247 693 | 167 893 | 0,13% | Acciones |
| Tetragon Partners GP Ltd | $4 247 238 | 167 875 | 0,13% | Acciones |
| GREAT LAKES ADVISORS, LLC | $3 822 526 | 151 088 | 0,12% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $3 635 306 | 143 688 | 0,11% | Acciones |
| STEMPOINT CAPITAL LP | $3 622 125 | 143 167 | 0,11% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $3 585 329 | 161 066 | 0,11% | Acciones |
| Squarepoint Ops LLC | $3 542 329 | 140 013 | 0,11% | Acciones |
| ORBIMED ADVISORS LLC | $3 466 100 | 137 000 | 0,11% | Acciones |
| Erste Asset Management GmbH | $3 369 240 | 133 700 | 0,10% | Acciones |
| Emerald Investment Advisers, LLC | $3 333 326 | 131 752 | 0,10% | Acciones |
| Caption Management, LLC | $3 289 000 | 130 000 | 0,10% | Opción de venta |
| VANGUARD ASSET MANAGEMENT, Ltd | $3 130 217 | 123 724 | 0,10% | Acciones |
| WELLS FARGO & COMPANY/MN | $3 084 475 | 121 916 | 0,09% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $3 077 311 | 138 244 | 0,09% | Acciones |
| Longaeva Partners L.P. | $2 968 145 | 117 318 | 0,09% | Acciones |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2 948 791 | 116 553 | 0,09% | Acciones |
| Trexquant Investment LP | $2 935 357 | 116 022 | 0,09% | Acciones |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $2 909 778 | 115 011 | 0,09% | Acciones |
| JONES FINANCIAL COMPANIES LLLP | $2 868 477 | 113 289 | 0,09% | Acciones |
| Rafferty Asset Management, LLC | $2 789 426 | 110 254 | 0,09% | Acciones |
| Nan Fung Group Holdings Ltd | $2 605 495 | 102 984 | 0,08% | Acciones |
| RAYMOND JAMES FINANCIAL INC | $2 406 232 | 95 108 | 0,07% | Acciones |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $2 344 000 | 92 648 | 0,07% | Acciones |
| ROYCE & ASSOCIATES LP | $2 324 691 | 91 885 | 0,07% | Acciones |
| HOHIMER WEALTH MANAGEMENT, LLC | $2 322 540 | 91 800 | 0,07% | Acciones |
| Point72 Europe (London) LLP | $2 305 047 | 108 015 | 0,07% | Acciones |
| VIRGINIA RETIREMENT SYSTEMS ET Al | $2 134 076 | 79 898 | 0,07% | Acciones |
| Campbell & CO Investment Adviser LLC | $2 108 527 | 83 341 | 0,06% | Acciones |
| Verdad Advisers, LP | $2 090 514 | 82 629 | 0,06% | Acciones |
| VOYA INVESTMENT MANAGEMENT LLC | $2 072 576 | 81 920 | 0,06% | Acciones |
| CITADEL ADVISORS LLC | $2 049 300 | 81 000 | 0,06% | Opción de compra |
| GUGGENHEIM CAPITAL LLC | $1 979 776 | 78 252 | 0,06% | Acciones |
| WESBANCO BANK INC | $1 978 460 | 78 200 | 0,06% | Acciones |
| Phocas Financial Corp. | $1 954 299 | 77 245 | 0,06% | Acciones |
| MetLife Investment Management, LLC | $1 899 043 | 75 061 | 0,06% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 850 493 | 73 142 | 0,06% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1 788 331 | 70 685 | 0,06% | Acciones |
| Freestone Grove Partners LP | $1 755 643 | 69 393 | 0,05% | Acciones |
| CenterBook Partners LP | $1 743 878 | 68 928 | 0,05% | Acciones |
| CANADA PENSION PLAN INVESTMENT BOARD | $1 722 930 | 68 100 | 0,05% | Acciones |
| Illinois Municipal Retirement Fund | $1 693 380 | 66 932 | 0,05% | Acciones |
Informantes de la empresa 37 insiders · 19 directivos · 19 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Stephen Davis | CEO | 6 de enero de 2024 M | 96 521 | 0 | 0 | $0 |
| Uli Hacksell | CEO | 25 de marzo de 2011 A | 69 916 | 0 | 0 | $0 |
| Elena Ridloff | EVP and CFO | 29 de abril de 2021 M | 10 553 | 0 | 0 | $0 |
| Todd S. Young | EVP AND CFO | 15 de octubre de 2018 A | — | 0 | 0 | $0 |
| Thomas H Aasen | Exec. VP, CFO & CBO | 25 de marzo de 2011 A | 13 899 | 0 | 0 | $0 |
| Srdjan R. Stankovic | President | 21 de noviembre de 2022 M | 61 234 | 0 | 0 | $0 |
| Mark R Brann | President & CSO | 16 de junio de 2006 S | 317 756 | 0 | 0 | $0 |
| Brendan Teehan | EVP, COO, Head of Commercial | 6 de enero de 2024 M | 30 949 | 0 | 0 | $0 |
| Elizabeth H.Z. Thompson | EVP, Head of Research & Dev | 29 de julio de 2026 M | 18 994 | 0 | 2 | $-432 662 |
| James Kihara | PRINCIPAL ACCOUNTING OFFICER | 26 de junio de 2026 S | 13 088 | 0 | 2 | $-412 253 |
| Austin D. Kim | EVP,General Counsel, Secretary | 6 de enero de 2024 M | 46 901 | 0 | 0 | $0 |
| Douglas J Williamson | Executive VP, Research & Dev | 10 de febrero de 2023 A | — | 0 | 0 | $0 |
| Michael J. Yang | EVP and CCO | 6 de enero de 2021 M | 8 059 | 0 | 0 | $0 |
| Eric Alejandro Miller | Controller & PAO | 15 de octubre de 2019 M | 270 | 0 | 0 | $0 |
| Glenn Baity | VP, GC & Sec. | 25 de marzo de 2011 A | — | 0 | 0 | $0 |
| Roger Mills | Executive VP, Development | 25 de marzo de 2011 A | — | 0 | 0 | $0 |
| Bo-Ragnar Tolf | VP/Mg. Dir. ACADIA Pharma AB | 8 de julio de 2009 M | 20 000 | 0 | 0 | $0 |
| Brian Lundstrom | Sr. VP, Bus. Development | 7 de marzo de 2008 A | 0 | 0 | 0 | $0 |
| Robert E Davis | Exec. VP, Drug Discovery | 11 de marzo de 2005 A | — | 0 | 0 | $0 |
| Adora Ndu | Consejero | 29 de mayo de 2026 A | 32 908 | 0 | 0 | $0 |
| Elizabeth A. Garofalo | Consejero | 29 de mayo de 2026 A | 33 489 | 0 | 0 | $0 |
| Jonathan Poole | Consejero | 29 de mayo de 2026 A | 2 010 | 0 | 0 | $0 |
| James M Daly | Consejero | 29 de mayo de 2026 A | 12 148 | 0 | 0 | $0 |
| Laura Brege | Consejero | 29 de mayo de 2026 A | 23 202 | 0 | 0 | $0 |
| Edmund Harrigan | Consejero | 29 de mayo de 2026 A | 43 148 | 0 | 0 | $0 |
| Daniel B Soland | Consejero | 1 de junio de 2023 A | 28 002 | 0 | 0 | $0 |
| Torsten Rasmussen | Consejero | 11 de junio de 2010 A | 4 000 | 0 | 0 | $0 |
| Leslie L Iversen | Consejero | 11 de junio de 2010 A | 9 000 | 0 | 0 | $0 |
| Mary Ann Gray | Consejero | 11 de junio de 2010 A | — | 0 | 0 | $0 |
| Michael T Borer | Consejero | 11 de junio de 2010 A | — | 0 | 0 | $0 |
| Lester J Ph D Kaplan | Consejero | 11 de junio de 2010 A | 4 000 | 0 | 0 | $0 |
| Gordon M Binder | Consejero | 12 de junio de 2009 A | 14 364 | 0 | 0 | $0 |
| Alan G Walton | Consejero | 12 de junio de 2009 A | 25 979 | 0 | 0 | $0 |
| Martien Van Osch | Consejero | 10 de junio de 2005 A | 1 168 892 | 0 | 0 | $0 |
| GORDON CARL L | Consejero | 20 de abril de 2005 A | 774 006 | 0 | 0 | $0 |
| Mark C. Schneyer | — | 6 de agosto de 2026 M | 67 828 | 0 | 3 | $-587 248 |
| John Joseph Kaiser | — | 20 de octubre de 2008 A | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 6 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Julian C. Baker, Felix J. Baker, FBB3 LLC ×14 presentaciones | 26 de febrero de 2026 | 25,40% | Enmienda | — | SEC |
| Baker Bros. Advisors, LLC, Felix J. Baker, Julian C. Baker ×4 presentaciones | 6 de junio de 2013 | — | Presentación inicial | — | SEC |
| Persona informante no revelada, Persona informante no revelada, Persona informante no revelada | 2 de mayo de 2005 | — | Presentación inicial | — | SEC |
| Persona informante no revelada, Persona informante no revelada, Persona informante no revelada | 2 de mayo de 2005 | — | Presentación inicial | — | SEC |
| Persona informante no revelada, Persona informante no revelada, Persona informante no revelada | 2 de mayo de 2005 | — | Presentación inicial | — | SEC |
| Oxford Bioscience Partners IV L.P., mRNA Fund II L.P., OBP Management IV L.P., Jeffrey T. Barnes, Mark P. Carthy, Jonathan J. Fleming, Michael E. Lytton, Alan G. Walton | 29 de abril de 2005 | — | Presentación inicial | Inversión pasiva | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 77 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IBRN · iShares Trust | 4,89% | 13 265 SH | 8 de agosto de 2026 | Diario |
| PBE · Invesco Exchange-Traded Fund Trust | 3,29% | 407 914 SH | 8 de agosto de 2026 | Diario |
| SBIO · ALPS ETF Trust | 2,35% | 175 740 NS | 31 de mayo de 2026 | N-PORT |
| PSCH · Invesco Exchange-Traded Fund Trust … | 1,87% | 109 972 SH | 8 de agosto de 2026 | Diario |
| BBP · ETFis Series Trust I | 1,32% | 34 855 NS | 30 de abril de 2026 | N-PORT |
| RZG · Invesco Exchange-Traded Fund Trust | 1,25% | 59 514 SH | 8 de agosto de 2026 | Diario |
| LABU · Direxion Shares ETF Trust | 0,85% | 195 542 NS | 30 de abril de 2026 | N-PORT |
| ROSC · Lattice Strategies Trust | 0,56% | 13 607 NS | 30 de abril de 2026 | N-PORT |
| IJT · iShares Trust | 0,40% | 1 176 933 SH | 8 de agosto de 2026 | Diario |
| OASC · Unified Series Trust | 0,39% | 15 269 NS | 31 de mayo de 2026 | N-PORT |
| IBB · iShares Trust | 0,37% | 1 239 145 SH | 8 de agosto de 2026 | Diario |
| VIOG · VANGUARD ADMIRAL FUNDS | 0,35% | 150 827 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,34% | 9 317 SH | 8 de agosto de 2026 | Diario |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,27% | 61 606 NS | 30 de abril de 2026 | N-PORT |
| BFOR · ALPS ETF Trust | 0,24% | 24 003 NS | 31 de mayo de 2026 | N-PORT |
| QVMS · Invesco Exchange-Traded Fund Trust … | 0,23% | 20 369 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,23% | 1 166 817 SH | 8 de agosto de 2026 | Diario |
| XJR · iShares Trust | 0,23% | 14 974 SH | 8 de agosto de 2026 | Diario |
| GSSC · Goldman Sachs ETF Trust | 0,20% | 89 945 NS | 31 de mayo de 2026 | N-PORT |
| IJR · iShares Trust | 0,20% | 7 728 433 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,19% | 137 860 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,19% | 6 303 NS | 31 de mayo de 2026 | N-PORT |
| VIOO · VANGUARD ADMIRAL FUNDS | 0,17% | 443 221 SH | 8 de agosto de 2026 | Diario |
| BKSE · BNY Mellon ETF Trust | 0,17% | 6 035 NS | 30 de abril de 2026 | N-PORT |
| SMMV · iShares Trust | 0,17% | 17 063 SH | 8 de agosto de 2026 | Diario |
| SMLF · iShares Trust | 0,15% | 219 745 SH | 8 de agosto de 2026 | Diario |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,15% | 47 683 NS | 30 de abril de 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,14% | 137 072 SH | 8 de agosto de 2026 | Diario |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,14% | 81 552 NS | 30 de abril de 2026 | N-PORT |
| SAA · ProShares Trust | 0,12% | 1 498 NS | 31 de mayo de 2026 | N-PORT |
| IWM · iShares Trust | 0,12% | 3 281 125 SH | 8 de agosto de 2026 | Diario |
| ISCG · iShares Trust | 0,11% | 39 884 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,10% | 741 237 SH | 8 de agosto de 2026 | Diario |
| RWJ · Invesco Exchange-Traded Fund Trust … | 0,09% | 66 331 SH | 8 de agosto de 2026 | Diario |
| VBK · VANGUARD INDEX FUNDS | 0,09% | 1 699 377 SH | 8 de agosto de 2026 | Diario |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,09% | 115 210 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,08% | 526 641 NS | 30 de abril de 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,08% | 16 957 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,07% | 5 921 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,06% | 599 784 NS | 31 de mayo de 2026 | N-PORT |
| ISCB · iShares Trust | 0,06% | 5 636 SH | 8 de agosto de 2026 | Diario |
| FHLC · FIDELITY COVINGTON TRUST | 0,04% | 54 956 NS | 30 de abril de 2026 | N-PORT |
| IEUS · iShares Trust | 0,04% | 7 411 SH | 8 de agosto de 2026 | Diario |
| SMDX · Tidal Trust III | 0,04% | 2 306 NS | 30 de abril de 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,04% | 4 033 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,04% | 4 631 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,04% | 1 457 036 SH | 8 de agosto de 2026 | Diario |
| VB · VANGUARD INDEX FUNDS | 0,04% | 2 944 095 SH | 8 de agosto de 2026 | Diario |
| PDN · Invesco Exchange-Traded Fund Trust … | 0,04% | 14 209 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,04% | 346 329 SH | 8 de agosto de 2026 | Diario |