DYN Dyne Therapeutics, Inc. - Common Stock
$26,41
Precio · Ago 19, 2026
Fundamentales a fecha de Jul 29, 2026
Rango 52S
$12–$27
94% of range
Calificación del Analista
BUY
21 analysts
Precio Objetivo
$39
+49% upside
P/E (TTM)
-7.6
ROE
-57.8%
Margen de Beneficio Neto
—
DYN Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$26.41
Capitalización Bursátil
$4.36B
P/E (TTM)
-7.6
BPA (TTM)
$-3.47
Ingresos (TTM)
—
Rendimiento div.
—
ROE
-57.8%
Deuda/Capital
—
Rango 52S
$12 – $27
DYN Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
—
BPA
$-3.47
2021-12-31
→
2025-12-31
Flujo de caja libre
$-405M
2020-12-31
→
2025-12-31
Márgenes
—
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
DYN
Mediana de Pares
P/E (TTM)
-7.6
13.2
P/B (P/C)
4.5
3.5
Price / FCF (Precio / FCF)
-10.8
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
DYN
Mediana de Pares
ROA
-47.5%
-42.2%
ROE
-57.8%
-52.8%
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
DYN
Mediana de Pares
Current Ratio (Ratio corriente)
22.3
10.3
Quick Ratio (Ratio Rápido)
17.6
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
DYN
Mediana de Pares
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
DYN
Mediana de Pares
DYN Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
21 analistas
- Compra fuerte 7 33,3%
- Compra 12 57,1%
- Mantener 2 9,5%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
15 analistas · 2026-08-15
Mediana
$40.00
Ahora
$26.41
Mín
$17.00
Máx
$50.00
Objetivo mediano
$40.00
+51,5%
Objetivo medio
$39.40
+49,2%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
-0.06%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-1.08 | $-0.76 | -0.32% |
| 31 de marzo de 2026 | $-0.73 | $-0.78 | 0.05% |
| 31 de diciembre de 2025 | $-0.76 | $-0.78 | 0.02% |
| 30 de septiembre de 2025 | $-0.76 | $-0.85 | 0.09% |
| 30 de junio de 2025 | $-0.97 | $-0.96 | -0.01% |
| 31 de marzo de 2025 | $-1.05 | $-0.89 | -0.16% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| DYN | $3.23B | -5.6 | — | — | -57.8% | — |
| CAI | $7.62B | -8.4 | 97.0% | -8.4% | -13.2% | — |
| PTCT | $6.19B | 9.8 | 114.5% | 39.4% | -331.5% | — |
| TVTX | $3.47B | -131.8 | 110.5% | -5.2% | -34.6% | — |
| ACAD | $4.55B | 11.6 | 11.9% | 36.5% | 38.1% | — |
| CELC | $4.81B | -26.3 | — | — | -244.3% | — |
| RLAY | $1.47B | -5.3 | 53.4% | -1800.6% | -44.9% | — |
| PBLS | — | — | — | — | — | — |
| TNGX | $1.20B | -10.2 | 48.3% | -162.8% | -42.2% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $398M | $281M | $211M | $143M | $121M | $45M | $11M | |
| SG&A Expense | $70M | $62M | $31M | $28M | $29M | $13M | $3M | |
| Operating Expenses | $468M | $344M | $242M | $171M | $150M | $59M | $14M | |
| Operating Income | $-468M | $-344M | $-242M | $-171M | $-150M | $-59M | $-14M | |
| Other Non-op | $22M | $26M | $6M | $3M | $734.0K | $-790.0K | $-1M | |
| Income Tax | $0 | $0 | $0 | · | · | · | · | |
| Net Income | $-446M | $-317M | $-236M | $-168M | $-149M | $-59M | $-15M | |
| EPS (Basic) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 | · | · | |
| EPS (Diluted) | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 | · | · | |
| EBITDA | $-466M | $-342M | $-240M | $-169M | $-149M | $-58M | · |
Balance general 20
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $893M | $435M | $122M | $172M | $201M | $301M | $15M | |
| Prepaid Expense | $16M | $17M | $6M | $10M | $6M | $4M | $127.0K | |
| Current Assets | $1.13B | $659M | $129M | $266M | $382M | $349M | $15M | |
| PP&E (Net) | $24M | $5M | $5M | $6M | $5M | $2M | $1M | |
| PP&E (Gross) | $33M | $12M | $10M | $10M | $7M | $3M | $2M | |
| Accum. Depreciation | $9M | $7M | $5M | $4M | $2M | $995.0K | $295.0K | |
| Other Non-current Assets | · | · | · | · | · | · | $191.0K | |
| Total Assets | $1.19B | $691M | $165M | $306M | $426M | $353M | $16M | |
| Accounts Payable | $8M | $7M | $23M | $5M | $4M | $3M | $1M | |
| Current Liabilities | $51M | $42M | $51M | $28M | $29M | $11M | $2M | |
| Capital Leases | $15M | $19M | $23M | $26M | $29M | $0 | · | |
| Total Liabilities | $215M | $61M | $74M | $54M | $57M | $11M | $2M | |
| Long-term Debt | $149M | $0 | · | · | · | · | · | |
| Common Stock | $16.0K | $10.0K | $6.0K | $6.0K | $6.0K | $5.0K | $1.0K | |
| Paid-in Capital | $2.37B | $1.58B | $724M | $650M | $597M | $422M | $6M | |
| Retained Earnings | $-1.40B | $-950M | $-633M | $-397M | $-228M | $-79M | $-20M | |
| AOCI | $475.0K | $6.0K | $0 | $-571.0K | $-269.0K | $-27.0K | · | |
| Stockholders' Equity | $972M | $630M | $91M | $252M | $368M | $342M | $14M | |
| Liabilities + Equity | $1.19B | $691M | $165M | $306M | $426M | $353M | $16M | |
| Shares Outstanding | 164,950,540 | 102,318,629 | 61,468,743 | 55,636,505 | 51,569,381 | 45,076,574 | 2,586,535 |
Flujo de Efectivo 13
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $2M | $2M | $1M | $700.0K | $271.0K | |
| Stock-based Comp | $46M | $46M | $20M | $15M | $18M | $7M | $26.0K | |
| Other Non-cash | $-5M | $-22M | $26M | $-2M | $11M | $6M | · | |
| Operating Cash Flow | $-403M | $-292M | $-188M | $-154M | $-120M | $-47M | $-12M | |
| CapEx | $2M | $2M | $729.0K | $3M | $4M | $1M | $2M | |
| Investing Cash Flow | $-29M | $-204M | $83M | $87M | $-138M | $-46M | $-2M | |
| Debt Issued | $148M | $0 | $0 | · | · | $10M | · | |
| Net Debt Issued | $148M | · | · | · | · | $10M | · | |
| Stock Issued | $141M | $98M | $52M | $37M | · | · | · | |
| Net Stock Activity | $141M | $98M | · | · | · | · | · | |
| Financing Cash Flow | $890M | $810M | $54M | $37M | $158M | $381M | $20M | |
| Net Change in Cash | $458M | $313M | $-51M | $-29M | $-100M | $289M | $7M | |
| Free Cash Flow | $-405M | $-295M | $-189M | $-157M | $-123M | $-48M | · |
Rentabilidad 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| ROA | -47.5% | -74.1% | -100.1% | -45.9% | -38.3% | -32.1% | · | |
| ROE | -57.8% | -47.5% | -193.9% | -67.0% | -38.2% | -16.8% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 22.3 | 15.6 | 2.5 | 9.5 | 13.3 | 31.8 | · | |
| Quick Ratio | 17.6 | 10.3 | 2.4 | 6.1 | 7.0 | 27.4 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-446M | $-317M | $-236M | $-168M | $-149M | $-59M | · | |
| Market Cap | $3.23B | $2.41B | $818M | $645M | $613M | $947M | · | |
| P/E | -5.6 | -7.0 | -3.4 | -3.6 | -4.1 | · | · | |
| P/B | 3.3 | 3.8 | 9.0 | 2.6 | 1.7 | 2.8 | · | |
| P / Tangible Book | 3.3 | 3.8 | 9.0 | 2.6 | 1.7 | 2.8 | · | |
| P / Cash Flow | -8.0 | -8.2 | -4.3 | -4.2 | -5.1 | -20.4 | · | |
| P / FCF | -8.0 | -8.2 | -4.3 | -4.1 | -5.0 | -19.9 | · | |
| Earnings Yield | -17.7% | -14.3% | -29.7% | -27.9% | -24.6% | · | · |
Estado de resultados 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $152M | $101M | $95M | $97M | $99M | $106M | $82M | $93M | $62M | $45M | $55M | $59M | $38M | $35M | $47M | $28M | |
| SG&A Expense | $29M | $24M | $21M | $17M | $17M | $16M | $15M | $13M | $10M | $25M | $7M | $8M | $8M | $8M | $6M | $8M | |
| Operating Expenses | $182M | $125M | $116M | $114M | $116M | $122M | $97M | $106M | $72M | $69M | $62M | $67M | $45M | $42M | $53M | $36M | |
| Operating Income | $-182M | $-125M | $-116M | $-114M | $-116M | $-122M | $-97M | $-106M | $-72M | $-69M | $-62M | $-67M | $-45M | $-42M | $-53M | $-36M | |
| Interest Expense | · | · | · | $3M | $94.0K | · | · | $0 | · | · | · | · | · | · | · | · | |
| Other Non-op | $3M | $4M | $4M | $6M | $5M | $7M | $8M | $9M | $7M | $4M | $2M | $2M | $1M | $894.0K | $451.0K | $200.0K | |
| Net Income | $-179M | $-121M | $-112M | $-108M | $-111M | $-115M | $-90M | $-97M | $-65M | $-66M | $-60M | $-65M | $-44M | $-41M | $-52M | $-36M | |
| EPS (Basic) | $-1.08 | $-0.73 | $-0.69 | $-0.76 | $-0.97 | $-1.05 | $-0.90 | $-0.96 | $-0.70 | $-0.81 | $-0.99 | $-1.08 | $-0.78 | $-0.80 | $-1.01 | $-0.69 | |
| EPS (Diluted) | $-1.08 | $-0.73 | $-0.69 | $-0.76 | $-0.97 | $-1.05 | $-0.90 | $-0.96 | $-0.70 | $-0.81 | $-0.99 | $-1.08 | $-0.78 | $-0.80 | $-1.01 | $-0.69 | |
| EBITDA | $-181M | $-125M | · | $-113M | $-115M | $-122M | · | $-105M | $-72M | $-69M | $-62M | $-66M | $-45M | $-42M | $-52M | $-35M |
Balance general 19
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $676M | $753M | $893M | $574M | $485M | $472M | $435M | $532M | $608M | $272M | $130M | $168M | $181M | $145M | $136M | $148M | |
| Prepaid Expense | $39M | $49M | $16M | $14M | $14M | $12M | $17M | $13M | $13M | $35M | $10M | $5M | $11M | $10M | $6M | $21M | |
| Current Assets | $938M | $1.02B | $1.13B | $806M | $698M | $690M | $659M | $736M | $792M | $488M | $168M | $213M | $249M | $258M | $298M | $344M | |
| PP&E (Net) | $25M | $24M | $24M | $24M | $6M | $6M | $5M | $5M | $5M | $5M | $5M | $5M | $6M | $6M | $5M | $6M | |
| PP&E (Gross) | $34M | $33M | $33M | $32M | $13M | $13M | $12M | $11M | $11M | $10M | $10M | $10M | $10M | $9M | $8M | $8M | |
| Accum. Depreciation | $10M | $9M | $9M | $8M | $8M | $7M | $7M | $7M | $6M | $6M | $5M | $4M | $4M | $3M | $3M | $2M | |
| Total Assets | $994M | $1.08B | $1.19B | $867M | $729M | $721M | $691M | $769M | $826M | $522M | $205M | $251M | $289M | $300M | $340M | $388M | |
| Accounts Payable | $12M | $11M | $8M | $12M | $14M | $7M | $7M | $6M | $2M | $7M | $4M | $3M | $9M | $919.0K | $7M | $5M | |
| Current Liabilities | $78M | $51M | $51M | $60M | $41M | $34M | $42M | $43M | $30M | $22M | $30M | $20M | $22M | $23M | $26M | $23M | |
| Capital Leases | $15M | $14M | $15M | $16M | $17M | $18M | $19M | $20M | $21M | $22M | $24M | $24M | $25M | $27M | $27M | $28M | |
| Total Liabilities | $292M | $215M | $215M | $175M | $158M | $52M | $61M | $63M | $51M | $44M | $53M | $45M | $47M | $50M | $53M | $51M | |
| Long-term Debt | $199M | $149M | $149M | $99M | $99M | · | $0 | · | · | · | · | · | · | · | · | · | |
| Common Stock | $16.0K | $16.0K | $16.0K | $14.0K | $11.0K | $11.0K | $10.0K | $10.0K | $10.0K | $9.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | |
| Paid-in Capital | $2.40B | $2.38B | $2.37B | $1.98B | $1.75B | $1.73B | $1.58B | $1.57B | $1.54B | $1.18B | $718M | $713M | $683M | $608M | $605M | $601M | |
| Retained Earnings | $-1.70B | $-1.52B | $-1.40B | $-1.28B | $-1.18B | $-1.07B | $-950M | $-860M | $-763M | $-698M | $-566M | $-506M | $-441M | $-358M | $-316M | $-264M | |
| AOCI | $-353.0K | $-137.0K | $475.0K | $496.0K | $252.0K | $241.0K | $6.0K | $478.0K | $-240.0K | $-132.0K | $-13.0K | $-56.0K | $-203.0K | $-983.0K | $-1M | $-930.0K | |
| Stockholders' Equity | $702M | $865M | $972M | $692M | $571M | $669M | $630M | $706M | $775M | $478M | $152M | $207M | $242M | $250M | $287M | $336M | |
| Liabilities + Equity | $994M | $1.08B | $1.19B | $867M | $729M | $721M | $691M | $769M | $826M | $522M | $205M | $251M | $289M | $300M | $340M | $388M | |
| Shares Outstanding | 165,670,880 | 165,201,329 | 164,950,540 | 142,613,248 | 114,338,610 | 113,633,782 | 102,318,629 | 101,753,378 | 100,119,518 | 87,089,649 | 61,322,283 | 61,013,986 | 58,305,480 | 51,906,773 | 51,734,361 | 51,649,423 |
Flujo de Efectivo 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $600.0K | $550.0K | $547.0K | $500.0K | $500.0K | $502.0K | $487.0K | $400.0K | $400.0K | $386.0K | $400.0K | $400.0K | $412.0K | $400.0K | $500.0K | $425.0K | |
| Stock-based Comp | $15M | $13M | $11M | $11M | $11M | $13M | $10M | $9M | $7M | $20M | $5M | $5M | $5M | $4M | $3M | $4M | |
| Other Non-cash | · | $-38M | · | · | · | $-4M | · | · | · | $-33M | · | · | $-8M | · | · | $-20M | |
| Operating Cash Flow | $-130M | $-145M | $-112M | $-91M | $-95M | $-106M | $-84M | $-75M | $-55M | $-79M | $-51M | $-56M | $-47M | $-43M | $-31M | $-51M | |
| CapEx | $2M | $221.0K | $484.0K | $395.0K | $60.0K | $981.0K | $1M | $253.0K | $857.0K | $191.0K | $167.0K | $250.0K | $230.0K | $886.0K | $261.0K | $1M | |
| Investing Cash Flow | $-5M | $-2M | $982.0K | $-38M | $7M | $1M | $-16M | $-19M | $11M | $-180M | $13M | $17M | $27M | $52M | $18M | $-2M | |
| Debt Issued | · | · | $49M | $0 | · | · | $0 | $0 | · | · | · | · | · | · | · | · | |
| Stock Issued | $0 | $0 | $0 | $0 | $0 | $141M | $0 | $0 | $24M | $74M | $0 | $24M | $28M | · | · | · | |
| Net Stock Activity | · | $0 | · | · | · | $141M | · | · | · | $74M | · | · | · | · | · | · | |
| Financing Cash Flow | $58M | $7M | $431M | $217M | $101M | $141M | $4M | $18M | $380M | $408M | $454.0K | $25M | $29M | $70.0K | $99.0K | $18.0K | |
| Net Change in Cash | $-77M | $-140M | $320M | $89M | $13M | $37M | $-97M | $-76M | $336M | $150M | $-37M | $-14M | $9M | $9M | $-12M | $-53M | |
| Free Cash Flow | · | $-145M | · | · | · | $-107M | · | · | · | $-79M | · | · | $-47M | · | · | $-52M |
Rentabilidad 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -20.7% | -13.4% | · | -13.2% | -14.3% | -18.6% | · | -19.9% | -12.1% | -16.2% | -23.8% | -21.9% | -13.1% | -10.8% | -13.0% | -8.1% | |
| ROE | -28.0% | -15.8% | · | -15.5% | -16.5% | -20.1% | · | -22.7% | -13.3% | -18.2% | -30.0% | -26.3% | -15.3% | -12.5% | -14.1% | -8.7% |
Liquidez y Solvencia 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 12.0 | 19.9 | · | 13.5 | 16.8 | 20.4 | · | 17.0 | 26.6 | 21.8 | 5.7 | 10.5 | 11.5 | 11.1 | 11.6 | 14.8 | |
| Quick Ratio | 8.7 | 14.7 | · | 9.6 | 11.7 | 13.9 | · | 12.3 | 20.4 | 12.2 | 4.4 | 8.3 | 8.4 | 6.2 | 5.3 | 6.4 | |
| Interest Coverage | · | · | · | -39.2 | -1231.8 | · | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-518M | $-455M | · | $-431M | $-388M | $-343M | · | $-288M | $-256M | $-235M | $-211M | $-203M | $-173M | $-172M | $-160M | $-133M | |
| Market Cap | $3.68B | $3.00B | · | $1.80B | $1.09B | $1.19B | · | $3.65B | $3.53B | $2.47B | $549M | $686M | $672M | $659M | $355M | $498M | |
| P/E | -6.3 | -5.2 | · | -3.4 | -2.6 | -3.0 | · | -10.4 | -9.9 | -7.8 | -2.5 | -3.1 | -3.5 | -3.8 | -2.2 | · | |
| P/B | 5.2 | 3.5 | · | 2.6 | 1.9 | 1.8 | · | 5.2 | 4.6 | 5.2 | 3.6 | 3.3 | 2.8 | 2.6 | 1.2 | 1.5 | |
| P / Tangible Book | 5.2 | 3.5 | · | 2.6 | 1.9 | 1.8 | · | 5.2 | 4.6 | 5.2 | 3.6 | 3.3 | 2.8 | 2.6 | 1.2 | 1.5 | |
| P / Cash Flow | · | -20.7 | · | · | · | -11.2 | · | · | · | -31.5 | · | · | -14.3 | · | · | -9.8 | |
| P / FCF | · | -20.6 | · | · | · | -11.1 | · | · | · | -31.4 | · | · | -14.2 | · | · | -9.5 | |
| Earnings Yield | -15.9% | -19.4% | · | -29.6% | -38.7% | -33.7% | · | -9.6% | -10.1% | -12.9% | -40.7% | -32.6% | -28.5% | -26.2% | -45.3% | · |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-446M | $-317M | $-236M | $-168M | $-149M |
| EPS Diluido | $-3.47 | $-3.37 | $-3.95 | $-3.23 | $-2.93 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 22.3 | 15.6 | 2.5 | 9.5 | 13.3 |
| Ratio Rápido | 17.6 | 10.3 | 2.4 | 6.1 | 7.0 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-405M | $-295M | $-189M | $-157M | $-123M |
Últimas noticias Noticias recientes que mencionan a esta empresa
Mis Métricas Tu lista de seguimiento personal — filas seleccionadas de Fundamentales Completos
📊
Elige las métricas que te importan — haz clic en el ➕ junto a cualquier fila en Fundamentales Completos arriba.
Tu selección se guarda y te sigue en todos los tickers.
Propietarios institucionales (13F) 261 declarantes · $2.5B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 54 (+19 vs trimestre anterior) | 27 (-14 vs trimestre anterior) | 87 (-11 vs trimestre anterior) | 70 (+7 vs trimestre anterior) | +15.5M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| STATE STREET CORP | $165 648 021 | 7 458 263 | 6,74% | Acciones |
| FMR LLC | $160 201 907 | 7 213 053 | 6,52% | Acciones |
| Orbis Allan Gray Ltd | $155 111 575 | 6 983 862 | 6,31% | Acciones |
| Atlas Venture Life Science Advisors, LLC | $151 030 199 | 6 800 099 | 6,14% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $140 166 621 | 6 310 969 | 5,70% | Acciones |
| TCG Crossover Management, LLC | $102 502 348 | 4 615 144 | 4,17% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $89 915 586 | 4 048 428 | 3,66% | Acciones |
| Vestal Point Capital, LP | $74 958 750 | 3 375 000 | 3,05% | Acciones |
| ORBIMED ADVISORS LLC | $71 864 542 | 3 235 684 | 2,92% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $71 309 878 | 3 209 934 | 2,90% | Acciones |
| Frazier Life Sciences Management, L.P. | $70 029 951 | 3 153 082 | 2,85% | Acciones |
| ARMISTICE CAPITAL, LLC | $68 567 289 | 3 087 226 | 2,79% | Acciones |
| PERCEPTIVE ADVISORS LLC | $59 727 909 | 2 689 235 | 2,43% | Acciones |
| Logos Global Management LP | $56 635 500 | 2 550 000 | 2,30% | Acciones |
| Venrock Adviser, LLC | $48 282 608 | 2 173 913 | 1,96% | Acciones |
| Siren, L.L.C. | $47 287 866 | 2 129 125 | 1,92% | Acciones |
| MPM BIOIMPACT LLC | $42 689 686 | 1 922 093 | 1,74% | Acciones |
| GOLDMAN SACHS GROUP INC | $41 625 071 | 1 874 159 | 1,69% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $40 865 556 | 1 839 962 | 1,66% | Acciones |
| Sofinnova Investments, Inc. | $36 832 709 | 1 658 384 | 1,50% | Acciones |
| Palo Alto Investors LP | $36 591 441 | 1 647 521 | 1,49% | Acciones |
| Vivo Capital, LLC | $34 591 320 | 1 557 466 | 1,41% | Acciones |
| Aberdeen Group plc | $34 190 829 | 1 539 434 | 1,39% | Acciones |
| Deep Track Capital, LP | $33 315 000 | 1 500 000 | 1,35% | Acciones |
| BANK OF AMERICA CORP /DE/ | $31 725 719 | 1 428 443 | 1,29% | Acciones |
| FCPM III SERVICES B.V. | $31 679 678 | 1 426 370 | 1,29% | Acciones |
| Polar Capital Holdings Plc | $28 580 072 | 1 286 811 | 1,16% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $26 700 929 | 1 202 203 | 1,09% | Acciones |
| CITADEL ADVISORS LLC | $25 407 307 | 1 143 958 | 1,03% | Acciones |
| Saturn V Capital Management LP | $23 486 920 | 1 057 493 | 0,96% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $21 964 557 | 988 949 | 0,89% | Acciones |
| NOVO HOLDINGS A/S | $21 330 351 | 960 394 | 0,87% | Acciones |
| Rock Springs Capital Management LP | $20 925 240 | 942 154 | 0,85% | Acciones |
| BRAIDWELL LP | $20 468 692 | 921 598 | 0,83% | Acciones |
| FRONTIER CAPITAL MANAGEMENT CO LLC | $19 414 605 | 874 138 | 0,79% | Acciones |
| BAKER BROS. ADVISORS LP | $18 066 702 | 813 449 | 0,73% | Acciones |
| SAMLYN CAPITAL, LLC | $14 875 658 | 669 773 | 0,61% | Acciones |
| Artisan Partners Limited Partnership | $14 653 847 | 659 786 | 0,60% | Acciones |
| TD Asset Management Inc | $12 173 568 | 548 112 | 0,50% | Acciones |
| ALGERT GLOBAL LLC | $11 244 323 | 506 273 | 0,46% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $9 591 389 | 431 850 | 0,39% | Acciones |
| Clearbridge Investments, LLC | $9 220 070 | 415 131 | 0,37% | Acciones |
| ArrowMark Colorado Holdings LLC | $8 822 278 | 397 221 | 0,36% | Acciones |
| MPM ASSET MANAGEMENT LLC | $8 632 056 | 682 376 | 0,35% | Acciones |
| WASATCH ADVISORS LP | $8 043 701 | 443 668 | 0,33% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $8 008 304 | 360 572 | 0,33% | Acciones |
| Tetragon Partners GP Ltd | $7 921 352 | 356 657 | 0,32% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $7 905 716 | 355 953 | 0,32% | Acciones |
| Granahan Investment Management, LLC | $7 519 529 | 338 565 | 0,31% | Acciones |
| University of Wisconsin Foundation | $6 964 146 | 313 559 | 0,28% | Acciones |
| MOORE CAPITAL MANAGEMENT, LP | $6 791 685 | 305 794 | 0,28% | Acciones |
| Squarepoint Ops LLC | $6 664 644 | 300 074 | 0,27% | Acciones |
| Fisher Asset Management, LLC | $6 629 795 | 298 505 | 0,27% | Acciones |
| AMERIPRISE FINANCIAL INC | $6 625 622 | 298 317 | 0,27% | Acciones |
| RAYMOND JAMES FINANCIAL INC | $6 468 951 | 291 263 | 0,26% | Acciones |
| Ensign Peak Advisors, Inc | $6 434 903 | 289 730 | 0,26% | Acciones |
| Alyeska Investment Group, L.P. | $5 447 624 | 245 278 | 0,22% | Acciones |
| Catalio Capital Management, LP | $5 439 873 | 244 929 | 0,22% | Acciones |
| Swiss National Bank | $5 152 720 | 232 000 | 0,21% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $4 432 983 | 199 594 | 0,18% | Acciones |
| SummitTX Capital, L.P. | $4 323 021 | 194 643 | 0,18% | Acciones |
| RHUMBLINE ADVISERS | $4 082 158 | 183 799 | 0,17% | Acciones |
| CITIGROUP INC | $3 998 733 | 180 042 | 0,16% | Acciones |
| HighVista Strategies LLC | $3 819 254 | 171 961 | 0,16% | Acciones |
| ALPS ADVISORS INC | $3 710 891 | 167 082 | 0,15% | Acciones |
| Y-Intercept (Hong Kong) Ltd | $3 469 269 | 156 203 | 0,14% | Acciones |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3 467 781 | 156 136 | 0,14% | Acciones |
| AXXCESS WEALTH MANAGEMENT, LLC | $3 448 547 | 155 270 | 0,14% | Acciones |
| Darwin Wealth Management, LLC | $3 448 546 | 155 270 | 0,14% | Acciones |
| Aegis Wealth Management LLC | $3 332 166 | 150 030 | 0,14% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $3 331 500 | 150 000 | 0,14% | Acciones |
| Woodline Partners LP | $3 317 907 | 149 388 | 0,13% | Acciones |
| BlackRock, Inc. | $3 223 182 | 145 123 | 0,13% | Acciones |
| Bank of New York Mellon Corp | $3 129 789 | 140 918 | 0,13% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $3 119 810 | 172 080 | 0,13% | Acciones |
| Schonfeld Strategic Advisors LLC | $2 992 841 | 134 752 | 0,12% | Acciones |
| XTX Topco Ltd | $2 793 707 | 125 786 | 0,11% | Acciones |
| Jain Global LLC | $2 583 934 | 116 341 | 0,11% | Acciones |
| Rafferty Asset Management, LLC | $2 556 415 | 115 102 | 0,10% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2 532 090 | 139 663 | 0,10% | Acciones |
| MORGAN STANLEY | $2 460 571 | 110 786 | 0,10% | Acciones |
| AXA Investment Managers S.A. | $2 064 872 | 163 231 | 0,08% | Acciones |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $1 933 798 | 87 069 | 0,08% | Acciones |
| JANUS HENDERSON GROUP PLC | $1 810 516 | 99 863 | 0,07% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $1 804 296 | 81 238 | 0,07% | Acciones |
| MetLife Investment Management, LLC | $1 771 803 | 79 775 | 0,07% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 746 195 | 78 622 | 0,07% | Acciones |
| FIFTH THIRD BANCORP | $1 684 826 | 75 859 | 0,07% | Acciones |
| CIBC WORLD MARKET INC. | $1 683 140 | 75 783 | 0,07% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 548 081 | 69 702 | 0,06% | Acciones |
| ENVESTNET ASSET MANAGEMENT INC | $1 478 808 | 66 583 | 0,06% | Acciones |
| VANGUARD GROUP INC | $1 433 904 | 73 308 | 0,06% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1 395 321 | 62 824 | 0,06% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 390 346 | 62 600 | 0,06% | Opción de venta |
| JANE STREET GROUP, LLC | $1 377 020 | 62 000 | 0,06% | Opción de venta |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $1 309 213 | 58 947 | 0,05% | Acciones |
| PROFUND ADVISORS LLC | $1 306 170 | 58 810 | 0,05% | Acciones |
| Invesco Ltd. | $1 212 555 | 54 595 | 0,05% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $1 210 400 | 54 498 | 0,05% | Acciones |
| Vanguard Global Advisers, LLC | $1 202 383 | 54 137 | 0,05% | Acciones |
Informantes de la empresa 26 insiders · 7 directivos · 10 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Joshua T Brumm | CEO & President | 11 de marzo de 2024 M | 537 998 | 0 | 0 | $0 |
| Susanna Gatti High | Chief Operating Officer | 18 de septiembre de 2024 S | 131 636 | 0 | 0 | $0 |
| Oxana Beskrovnaya | Chief Scientific Officer | 11 de marzo de 2025 S | 195 840 | 0 | 0 | $0 |
| Richard William Scalzo | SVP, Head of Finance & Admin. | 11 de marzo de 2025 S | 122 330 | 0 | 0 | $0 |
| Wildon Farwell | Chief Medical Officer | 19 de agosto de 2024 S | 143 222 | 0 | 0 | $0 |
| Jonathan Mcneill | Chief Business Officer | 19 de agosto de 2024 S | 132 106 | 0 | 0 | $0 |
| Romesh Subramanian | Chief Scientific Officer | 16 de septiembre de 2020 A | 566 249 | 0 | 0 | $0 |
| Dirk Kersten | Consejero | 27 de julio de 2026 S | 3 586 796 | 0 | 19 | $-38 570 974 |
| Barry E Greene | Consejero | 22 de junio de 2026 A | — | 0 | 0 | $0 |
| Carlo Incerti | Consejero | 5 de junio de 2026 A | 0 | 0 | 0 | $0 |
| Catherine Stehman-Breen | Consejero | 5 de junio de 2026 A | 115 713 | 0 | 0 | $0 |
| David Charles Lubner | Consejero | 5 de junio de 2026 A | 0 | 0 | 0 | $0 |
| Brian S Posner | Consejero | 5 de junio de 2026 A | 24 500 | 7 | 0 | $274 840 |
| Edward Hurwitz | Consejero | 5 de junio de 2026 A | 91 081 | 0 | 0 | $0 |
| Vikram Karnani | Consejero | 22 de diciembre de 2025 A | — | 0 | 0 | $0 |
| Lawrence Otto Klein | Consejero | 5 de julio de 2022 A | 10 725 | 0 | 0 | $0 |
| Atlas Venture Fund XI, L.P. | Propietario del 10% | 13 de julio de 2021 J | 7 326 117 | 0 | 0 | $0 |
| CureDuchenne Ventures, LLC | Propietario del 10% | 21 de septiembre de 2020 C | 602 972 | 0 | 0 | $0 |
| Forbion Capital Fund IV Cooperatief U.A. | Propietario del 10% | 21 de septiembre de 2020 C | 6 131 079 | 0 | 0 | $0 |
| Logos Global Management LP | Propietario del 10% | 21 de septiembre de 2020 C | 1 504 392 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | Propietario del 10% | 21 de septiembre de 2020 C | 1 608 785 | 0 | 0 | $0 |
| Jason P Rhodes | — | 14 de agosto de 2026 S | 428 946 | 0 | 31 | $-99 402 433 |
| Johanna Friedl-Naderer | — | 13 de agosto de 2026 S | 153 982 | 0 | 7 | $-31 766 |
| Douglas Kerr | — | 13 de agosto de 2026 S | 167 599 | 0 | 7 | $-176 412 |
| Erick Lucera | — | 13 de agosto de 2026 S | 119 766 | 0 | 4 | $-228 675 |
| John Cox | — | 13 de agosto de 2026 S | 363 165 | 0 | 5 | $-336 865 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 1 tenencia
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Vida Ventures II, LLC, Vida Ventures II-A, LLC, VV Manager II, LLC ×2 presentaciones | 10 de febrero de 2023 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 52 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IBRN · iShares Trust | 3,47% | 10 352 SH | 8 de agosto de 2026 | Diario |
| BBC · ETFis Series Trust I | 0,67% | 14 322 NS | 30 de abril de 2026 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,67% | 4 266 NS | 30 de abril de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,67% | 196 941 NS | 30 de abril de 2026 | N-PORT |
| IBB · iShares Trust | 0,30% | 1 099 711 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,30% | 8 997 SH | 8 de agosto de 2026 | Diario |
| ESSC · Strategy Shares | 0,18% | 2 581 NS | 30 de abril de 2026 | N-PORT |
| IWN · iShares Trust | 0,16% | 919 017 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,16% | 6 087 NS | 31 de mayo de 2026 | N-PORT |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,13% | 77 375 SH | 8 de agosto de 2026 | Diario |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,12% | 51 630 NS | 30 de abril de 2026 | N-PORT |
| IWM · iShares Trust | 0,12% | 3 833 065 SH | 8 de agosto de 2026 | Diario |
| BKSE · BNY Mellon ETF Trust | 0,10% | 4 423 NS | 30 de abril de 2026 | N-PORT |
| ISCG · iShares Trust | 0,09% | 36 532 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,09% | 784 894 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,08% | 463 505 SH | 8 de agosto de 2026 | Diario |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,08% | 82 893 SH | 8 de agosto de 2026 | Diario |
| ESML · iShares Trust | 0,08% | 84 297 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,07% | 57 752 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,06% | 6 271 NS | 31 de mayo de 2026 | N-PORT |
| ISCB · iShares Trust | 0,06% | 6 733 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,06% | 50 849 SH | 8 de agosto de 2026 | Diario |
| SCHA · SCHWAB STRATEGIC TRUST | 0,06% | 688 953 NS | 31 de mayo de 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,05% | 47 064 SH | 8 de agosto de 2026 | Diario |
| DFAS · Dimensional ETF Trust | 0,05% | 390 218 NS | 30 de abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,04% | 1 689 620 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,04% | 347 244 SH | 8 de agosto de 2026 | Diario |
| ISCV · iShares Trust | 0,04% | 10 732 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,04% | 4 905 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,03% | 53 716 NS | 30 de abril de 2026 | N-PORT |
| WSML · iShares Trust | 0,03% | 8 466 SH | 8 de agosto de 2026 | Diario |
| VBR · VANGUARD INDEX FUNDS | 0,03% | 1 020 875 SH | 8 de agosto de 2026 | Diario |
| URTY · ProShares Trust | 0,03% | 4 964 NS | 31 de mayo de 2026 | N-PORT |
| TILT · FlexShares Trust | 0,02% | 25 564 NS | 30 de abril de 2026 | N-PORT |
| VB · VANGUARD INDEX FUNDS | 0,02% | 1 607 020 SH | 8 de agosto de 2026 | Diario |
| SMLF · iShares Trust | 0,02% | 32 751 SH | 8 de agosto de 2026 | Diario |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 4 701 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,01% | 125 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 44 010 NS | 31 de mayo de 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,01% | 11 272 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 9 076 NS | 30 de abril de 2026 | N-PORT |
| ITOT · iShares Trust | 0,01% | 199 812 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,01% | 38 879 SH | 8 de agosto de 2026 | Diario |
| DFAC · Dimensional ETF Trust | 0,00% | 123 282 NS | 30 de abril de 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 84 436 NS | 31 de mayo de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 21 333 NS | 30 de abril de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 720 NS | 30 de abril de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 33 452 NS | 30 de abril de 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 5 252 NS | 31 de mayo de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 4 473 029 SH | 8 de agosto de 2026 | Diario |