CRIS Curis, Inc. - Common Stock
$1,88
Precio · Ago 18, 2026
Fundamentales a fecha de Ago 14, 2026
Rango 52S
$0–$9
19% of range
Calificación del Analista
BUY
10 analysts
Precio Objetivo
$43
+2170% upside
P/E (TTM)
-0.2
ROE
177.9%
Margen de Beneficio Neto
-80.3%
CRIS Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$1.88
Capitalización Bursátil
$1M
P/E (TTM)
-0.2
BPA (TTM)
$-0.58
Ingresos (TTM)
$9M
Rendimiento div.
—
ROE
177.9%
Deuda/Capital
0.0
Rango 52S
$0 – $9
CRIS Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
$9M
2016-12-31
→
2025-12-31
BPA
$-0.58
2019-12-31
→
2025-12-31
Flujo de caja libre
—
2016-12-31
→
2023-12-31
Márgenes
-80.3%
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
CRIS
Mediana de Pares
P/E (TTM)
-0.2
—
P/S (TTM) (P/V (TTM))
0.1
2.9
P/B (P/C)
0.2
1.1
EV / EBITDA
0.7
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
CRIS
Mediana de Pares
Operating Margin (Margen Operativo)
-60.5%
—
Net Profit Margin (Margen de Beneficio Neto)
-80.3%
-4409.1%
ROA
-24.8%
-111.4%
ROE
177.9%
-169.4%
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
CRIS
Mediana de Pares
Debt / Equity (Deuda / Patrimonio)
0.0
0.0
Current Ratio (Ratio corriente)
0.5
1.9
Quick Ratio (Ratio Rápido)
0.4
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
CRIS
Mediana de Pares
Revenue YoY (Ingresos interanuales)
-13.4%
—
Revenue CAGR 3Y (Ingresos CAGR 3A)
-2.4%
—
Revenue CAGR 5Y (Ingresos CAGR 5A)
-2.7%
—
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
CRIS
Mediana de Pares
CRIS Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
10 analistas
- Compra fuerte 2 20,0%
- Compra 7 70,0%
- Mantener 1 10,0%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
3 analistas · 2026-08-16
Mediana
$43.00
← Por Debajo de Todos los Objetivos
$1.88
Mín
$20.00
Máx
$65.00
Objetivo mediano
$43.00
+2187,2%
Objetivo medio
$42.67
+2169,5%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
-1.8%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 31 de marzo de 2026 | $-25.00 | $-8.16 | -16.8% |
| 31 de diciembre de 2025 | $-10.00 | $-9.18 | -0.82% |
| 30 de septiembre de 2025 | $-9.80 | $-11.79 | 2.0% |
| 30 de junio de 2025 | $-13.60 | $-18.16 | 4.6% |
| 31 de marzo de 2025 | $-1.25 | $-1.21 | -0.04% |
| 31 de diciembre de 2024 | $-1.25 | $-1.39 | 0.14% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| CRIS | $13M | -1.7 | -13.4% | -80.3% | 177.9% | — |
| HCWB | — | -0.1 | -97.9% | -14677.1% | -586.8% | 20.0% |
| REVB | — | — | — | — | — | — |
| SILO | $5M | -0.7 | 0.00% | -5863.5% | -75.3% | 38.6% |
| VIVS | $4M | -0.3 | -9.0% | -10567.2% | -294.8% | — |
| RNAZ | — | -0.1 | — | — | — | — |
| ONCO | $2M | -0.1 | -67.7% | -1721.0% | -129.5% | 77.6% |
| BIAF | — | — | — | — | — | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 15
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $9M | $11M | $10M | $10M | $11M | $11M | $10M | $10M | $10M | $8M | $8M | $10M | |
| R&D Expense | · | · | · | · | · | · | · | · | · | $18M | · | $14M | |
| SG&A Expense | $14M | $17M | $19M | $20M | $17M | $12M | $12M | $15M | $14M | $16M | $13M | $12M | |
| Operating Expenses | $42M | $55M | $58M | $63M | $53M | $36M | $34M | $40M | $60M | $66M | $64M | $26M | |
| Operating Income | $-6M | $-45M | $-48M | $-53M | $-42M | $-25M | $-24M | $-29M | $-50M | $-58M | $-56M | $-16M | |
| Interest Expense | · | · | · | · | $0 | $0 | $791.0K | $4M | $4M | $3M | $3M | $4M | |
| Interest Income | $316.0K | $2M | $3M | $1M | $211.0K | $63.0K | $614.0K | $684.0K | $513.0K | $406.0K | $277.0K | $165.0K | |
| Other Non-op | $-2M | $1M | $919.0K | $-4M | $890.0K | $22.0K | $-58.0K | $0 | $-4M | $-2M | $-2M | $-3M | |
| Income Tax | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Income | $-8M | $-43M | $-47M | $-57M | $-45M | $-30M | $-32M | $-33M | $-53M | $-60M | $-59M | $-19M | |
| EPS (Basic) | $-0.58 | $-6.88 | $-8.96 | $-12.14 | $0.50 | $-0.61 | $-0.97 | · | · | · | · | · | |
| EPS (Diluted) | $-0.58 | $-6.88 | $-8.96 | $-12.14 | $0.50 | $-0.61 | $-0.97 | · | · | · | · | · | |
| Shares (Basic) | 13,164,032 | 6,306,284 | 5,293,294 | 4,669,626 | 91,569,154 | 48,670,381 | 33,180,516 | · | · | · | · | · | |
| Shares (Diluted) | 13,164,032 | 6,306,284 | 5,293,294 | 4,669,626 | 91,569,154 | 48,670,381 | 33,180,516 | · | · | · | · | · | |
| EBITDA | $-6M | $-45M | $-48M | · | $-42M | $-25M | $-24M | $-29M | $-50M | $-58M | $-56M | $-16M |
Balance general 27
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $5M | $20M | $27M | $20M | $40M | $130M | $15M | $24M | $38M | $26M | $33M | $8M | |
| Short-term Investments | · | $0 | $30M | $66M | $76M | $39M | $5M | $634.0K | $22M | $18M | $49M | $42M | |
| Receivables | $0 | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | |
| Prepaid Expense | $2M | $3M | $2M | $4M | $3M | $1M | $1M | $827.0K | $989.0K | $1M | $1M | $489.8K | |
| Current Assets | $7M | $26M | $61M | $92M | $122M | $173M | $25M | $28M | $64M | $48M | $86M | $52M | |
| PP&E (Net) | $62.0K | $231.0K | $434.0K | $689.0K | $505.0K | $663.0K | $154.0K | $267.0K | $400.0K | $400.0K | $300.0K | $407.7K | |
| PP&E (Gross) | $913.0K | $1M | $2M | $3M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Accum. Depreciation | $851.0K | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Goodwill | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | |
| Other Non-current Assets | $2M | $2M | $3M | $2M | $0 | $3.0K | $3.0K | $2.0K | $3.0K | $3.0K | $51.0K | $67.5K | |
| Total Assets | $20M | $41M | $77M | $109M | $162M | $204M | $35M | $37M | $74M | $58M | $95M | $63M | |
| Accounts Payable | $6M | $3M | $3M | $3M | $6M | $4M | $4M | $3M | $5M | $6M | $4M | $2M | |
| Accrued Liabilities | $7M | $7M | $9M | $6M | $6M | $4M | $2M | $3M | $3M | $3M | $2M | $2M | |
| Current Liabilities | $14M | $19M | $22M | $10M | $13M | $10M | $7M | $13M | $14M | $14M | $11M | $10M | |
| Capital Leases | $428.0K | $2M | $1M | $3M | $4M | $5M | $0 | · | · | · | · | · | |
| Other Non-current Liabilities | · | · | · | · | $0 | $334.0K | $0 | $11.0K | $34.0K | $18.0K | $139.0K | $174.0K | |
| Total Liabilities | $15M | $47M | $58M | $62M | $72M | $74M | $69M | $42M | $50M | $28M | $30M | $33M | |
| Long-term Debt | · | · | · | · | · | $891.0K | $0 | $35M | $42M | $20M | $24M | $28M | |
| Total Debt | $0 | $8M | · | · | $0 | $557.0K | $0 | $35M | $42M | $20M | $24M | $28M | |
| Common Stock | $6.0K | $85.0K | $59.0K | $48.0K | $916.0K | $915.0K | $332.0K | $332.0K | $331.0K | $1M | $1M | $872.5K | |
| Paid-in Capital | · | · | · | · | · | · | · | · | · | · | · | $810M | |
| Retained Earnings | $-1.25B | $-1.24B | $-1.20B | $-1.15B | $-1.09B | $-1.05B | $-1.02B | $-985M | $-952M | $-899M | $-839M | $-780M | |
| Treasury Stock | · | · | · | · | · | · | · | $0 | $2M | $2M | $2M | $2M | |
| AOCI | · | $0 | $229.0K | $-186.0K | $-109.0K | $-3.0K | $0 | $0 | $-2.0K | $-4.0K | $28.0K | $-11.0K | |
| Stockholders' Equity | $5M | $-6M | $20M | $47M | $91M | $131M | $-34M | $-4M | $24M | $29M | $65M | $30M | |
| Liabilities + Equity | $20M | $41M | $77M | $109M | $162M | $204M | $35M | $37M | $74M | $58M | $95M | $63M | |
| Shares Outstanding | 646,537 | 8,487,818 | 5,894,085 | 4,830,464 | 91,645,369 | 91,502,461 | 33,241,793 | 33,159,253 | 32,831,380 | 141,124,025 | 128,990,378 | 86,030,811 |
Flujo de Efectivo 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $169.0K | $203.0K | $255.0K | $233.0K | $158.0K | $144.0K | $125.0K | $177.0K | $235.0K | $193.0K | $200.0K | $200.0K | |
| Stock-based Comp | $4M | $6M | $6M | $7M | $5M | $3M | $3M | $4M | $5M | $4M | $4M | $3M | |
| Operating Cash Flow | $-27M | $-40M | $-38M | $-54M | $-38M | $-26M | $-26M | $-30M | $-48M | $-36M | $-30M | $-17M | |
| CapEx | · | · | $0 | $416.0K | $0 | $677.0K | $41.0K | $85.0K | $188.0K | $329.0K | $48.0K | $92.0K | |
| Investing Cash Flow | $2M | $29M | $38M | $33M | $-48M | $-49M | $-4M | $21M | $-4M | $30M | $-6M | $16M | |
| Stock Issued | $15M | $12M | $14M | $6M | $0 | $159M | $0 | $0 | $42M | $0 | $65M | $0 | |
| Net Stock Activity | $15M | $12M | $14M | · | $0 | $159M | · | $0 | $42M | $0 | $65M | $282.8K | |
| Financing Cash Flow | $10M | $3M | $8M | $867.0K | $-4M | $189M | $23M | $-6M | $64M | $-1M | $62M | $-1M | |
| Net Change in Cash | $-15M | $-7M | $7M | $-20M | $-90M | $114M | $-7M | $-15M | $12M | $-7M | $25M | $-2M | |
| Free Cash Flow | · | · | $-38M | · | $-38M | $-26M | $-26M | $-30M | $-49M | $-36M | $-30M | $-17M |
Rentabilidad 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -60.5% | -408.3% | -482.2% | · | -395.0% | -229.8% | -243.5% | -281.3% | -502.7% | -771.1% | -716.9% | -161.1% | |
| Net Margin | -80.3% | -397.8% | -473.0% | · | -426.7% | -276.0% | -320.9% | -312.6% | -538.7% | -802.6% | -748.6% | -190.3% | |
| EBITDA Margin | -60.5% | -408.3% | -482.2% | · | -395.0% | -229.8% | -243.5% | -281.3% | -502.7% | -771.1% | -716.9% | -161.1% | |
| ROA | -24.8% | -73.2% | -50.9% | · | -24.8% | -25.0% | -88.6% | -58.7% | -81.1% | -79.1% | -74.9% | -26.2% | |
| ROE | 177.9% | 589.0% | -192.5% | · | -46.9% | -58.6% | 107.1% | 1755.5% | -199.5% | -128.8% | -125.1% | -50.0% |
Liquidez y Solvencia 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 0.5 | 1.4 | 4.5 | · | 9.1 | 17.1 | 3.8 | 2.1 | 4.6 | 3.6 | 7.9 | 5.2 | |
| Quick Ratio | 0.4 | 1.2 | 4.4 | · | 8.9 | 17.0 | 3.6 | 2.0 | 4.5 | 3.5 | 7.8 | 5.1 | |
| Debt / Equity | 0.0 | -1.3 | · | · | 0.0 | 0.0 | 0.0 | -7.9 | 1.7 | 0.7 | 0.4 | 1.0 | |
| LT Debt / Equity | · | · | · | · | · | · | 0.0 | -6.4 | 1.5 | 0.5 | 0.3 | 0.8 | |
| Interest Coverage | · | · | · | · | · | · | -30.8 | -7.5 | -12.5 | -20.9 | -17.0 | -4.2 |
Eficiencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.3 | 0.2 | 0.1 | · | 0.1 | 0.1 | 0.3 | 0.2 | 0.2 | 0.1 | 0.1 | 0.1 | |
| Receivables Turnover | 5.6 | 3.6 | 3.5 | · | 3.4 | 3.4 | 3.3 | 3.5 | 3.6 | 3.3 | 3.9 | 5.7 |
Tasas de Crecimiento 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | -13.4% | 8.8% | -1.4% | -4.6% | -1.7% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | -2.4% | 0.80% | -2.6% | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | -2.7% | · | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $9M | $11M | $10M | $10M | $11M | $11M | $10M | $10M | $10M | $8M | $8M | $10M | |
| Net Income TTM | $-8M | $-43M | $-47M | $-57M | $-45M | $-30M | $-32M | $-33M | $-53M | $-60M | $-59M | $-19M | |
| Market Cap | $13M | $26M | $75M | · | $8.72B | $14.99B | $1.13B | $458M | $11.49B | $43.47B | $37.54B | $12.90B | |
| Enterprise Value | $8M | $14M | · | · | $8.61B | $14.82B | $1.11B | $469M | $11.47B | $43.44B | $37.48B | $12.88B | |
| P/E | -1.7 | -0.4 | -1.4 | -0.9 | 190.4 | -268.5 | -35.1 | · | · | · | · | · | |
| P/S | 1.4 | 2.4 | 7.5 | · | 819.3 | 1383.3 | 113.0 | 43.9 | 1160.9 | 5774.7 | 4764.7 | 1311.0 | |
| P/B | 2.3 | -4.3 | 3.8 | · | 96.2 | 114.7 | -33.3 | -101.8 | 478.9 | 1485.2 | 581.9 | 433.3 | |
| P / Tangible Book | · | · | 7.0 | 28.3 | 106.8 | 123.2 | · | · | · | · | · | · | |
| P / Cash Flow | -0.5 | -0.7 | -2.0 | · | -231.9 | -582.3 | -43.1 | -15.2 | -237.6 | -1213.8 | -1255.8 | -767.5 | |
| P / FCF | · | · | -2.0 | · | -231.9 | -567.4 | -43.1 | -15.2 | -236.7 | -1202.7 | -1253.8 | -763.4 | |
| EV / EBITDA | -1.4 | -0.3 | · | · | -204.7 | -595.2 | -45.6 | -16.0 | -230.6 | -748.5 | -663.6 | -812.2 | |
| EV / FCF | · | · | · | · | -228.8 | -561.0 | -42.3 | -15.5 | -236.3 | -1202.0 | -1251.8 | -762.1 | |
| EV / Revenue | 0.8 | 1.2 | · | · | 808.4 | 1367.8 | 110.9 | 45.0 | 1159.1 | 5771.4 | 4757.3 | 1308.9 | |
| Earnings Yield | -58.6% | -224.8% | -70.3% | -110.4% | 0.53% | -0.37% | -2.9% | · | · | · | · | · |
Estado de resultados 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $0 | $0 | $1M | $3M | $3M | $2M | $3M | $3M | $3M | $2M | $3M | $3M | $2M | $2M | $3M | $3M | |
| SG&A Expense | $3M | $5M | $3M | $4M | $4M | $4M | $3M | $4M | $5M | $5M | $5M | $5M | $4M | $5M | $4M | $5M | |
| Operating Expenses | $10M | $12M | $9M | $10M | $11M | $13M | $12M | $13M | $15M | $15M | $15M | $15M | $14M | $14M | $13M | $15M | |
| Operating Income | $-10M | $-12M | $20M | $-7M | $-8M | $-10M | $-9M | $-11M | $-13M | $-12M | $-12M | $-12M | $-12M | $-12M | $-10M | $-13M | |
| Interest Income | $62.0K | $77.0K | $51.0K | $80.0K | $92.0K | $93.0K | $227.0K | $325.0K | $701.0K | $515.0K | $665.0K | $806.0K | $815.0K | $652.0K | $542.0K | $335.0K | |
| Other Non-op | $1M | $-13M | $-263.0K | $-805.0K | $-342.0K | $-459.0K | $-624.0K | $475.0K | $709.0K | $593.0K | $487.0K | $187.0K | $177.0K | $68.0K | $-1M | $-688.0K | |
| Net Income | $-9M | $-24M | $19M | $-8M | $-9M | $-11M | $-10M | $-10M | $-12M | $-12M | $-12M | $-12M | $-12M | $-12M | $-11M | $-13M | |
| EPS (Basic) | $-4.02 | $-1.25 | $1.84 | $-0.49 | $-13.61 | $-1.25 | $-1.10 | $-1.70 | $-2.03 | $-2.05 | $-1.97 | $-2.13 | $-2.47 | $-2.39 | $-8.96 | $-2.83 | |
| EPS (Diluted) | $-4.02 | $-1.25 | $1.84 | $-0.49 | $-13.61 | $-1.25 | $-1.10 | $-1.70 | $-2.03 | $-2.05 | $-1.97 | $-2.13 | $-2.47 | $-2.39 | $-8.96 | $-2.83 | |
| Shares (Basic) | 2,135,906 | 19,363,478 | -23,637,672 | 15,680,178 | 631,475 | 8,493,886 | -11,236,641 | 5,940,924 | 5,818,416 | 5,783,585 | -10,092,639 | 5,720,789 | 4,834,381 | 4,830,763 | -183,316,252 | 4,689,559 | |
| Shares (Diluted) | 2,135,906 | 19,363,478 | -23,637,672 | 15,680,178 | 631,475 | 8,493,886 | -11,236,641 | 5,940,924 | 5,818,416 | 5,783,585 | -10,092,639 | 5,720,789 | 4,834,381 | 4,830,763 | -183,316,252 | 4,689,559 | |
| EBITDA | $-10M | $-12M | · | $-7M | $-8M | $-10M | · | $-11M | $-13M | $-12M | · | $-12M | $-12M | $-12M | · | $-13M |
Balance general 23
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $5M | $15M | $5M | $9M | $10M | $20M | $20M | $21M | $10M | $30M | $27M | $24M | $20M | $32M | $20M | $30M | |
| Short-term Investments | · | · | · | · | · | · | · | $0 | $18M | $11M | $30M | $44M | $44M | $40M | $66M | $69M | |
| Receivables | · | · | $0 | $3M | $3M | $2M | $3M | $3M | $3M | $2M | $3M | $3M | $2M | $2M | $3M | $3M | |
| Prepaid Expense | $1M | $2M | $2M | $2M | $2M | $2M | $3M | $3M | $4M | $3M | $2M | $2M | $2M | $4M | $4M | $4M | |
| Current Assets | $7M | $17M | $7M | $14M | $14M | $25M | $26M | $27M | $35M | $46M | $61M | $73M | $68M | $78M | $92M | $106M | |
| PP&E (Net) | $46.0K | $54.0K | $62.0K | $98.0K | $130.0K | $172.0K | $231.0K | $246.0K | $308.0K | $370.0K | $434.0K | $497.0K | $561.0K | $625.0K | $689.0K | $780.0K | |
| PP&E (Gross) | · | · | $913.0K | · | · | · | $1M | · | · | · | $2M | · | · | · | $3M | · | |
| Accum. Depreciation | · | · | $851.0K | · | · | · | $1M | · | · | · | $2M | · | · | · | $2M | · | |
| Goodwill | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | $9M | |
| Other Non-current Assets | $2M | $2M | $2M | $2M | $3M | $2M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | |
| Total Assets | $19M | $30M | $20M | $28M | $29M | $39M | $41M | $42M | $50M | $62M | $77M | $90M | $84M | $95M | $109M | $123M | |
| Accounts Payable | $5M | $7M | $6M | $4M | $4M | $5M | $3M | $4M | $2M | $4M | $3M | $5M | $3M | $3M | $3M | $6M | |
| Accrued Liabilities | $7M | $7M | $7M | $7M | $7M | $6M | $7M | $8M | $7M | $6M | $9M | $7M | $6M | $4M | $6M | $7M | |
| Current Liabilities | $14M | $15M | $14M | $20M | $19M | $20M | $19M | $22M | $19M | $11M | $22M | $14M | $10M | $8M | $10M | $14M | |
| Capital Leases | $0 | $108.0K | $428.0K | $740.0K | $1M | $1M | $2M | $2M | $2M | $1M | $1M | $2M | $2M | $2M | $3M | $3M | |
| Total Liabilities | $14M | $17M | $15M | $42M | $43M | $46M | $47M | $51M | $51M | $53M | $58M | $60M | $58M | $58M | $62M | $67M | |
| Total Debt | · | · | · | $7M | $7M | $7M | · | · | · | · | · | · | · | · | · | · | |
| Common Stock | $19.0K | $400.0K | $129.0K | $127.0K | $107.0K | $105.0K | $85.0K | $60.0K | $59.0K | $59.0K | $59.0K | $59.0K | $993.0K | $966.0K | $48.0K | $964.0K | |
| Retained Earnings | $-1.28B | $-1.27B | $-1.25B | $-1.27B | $-1.26B | $-1.25B | $-1.24B | $-1.23B | $-1.22B | $-1.21B | $-1.20B | $-1.18B | $-1.17B | $-1.16B | $-1.15B | $-1.14B | |
| AOCI | · | · | · | · | · | · | · | $0 | $42.0K | $338.0K | $229.0K | $103.0K | $2.0K | $9.0K | $-186.0K | $-479.0K | |
| Stockholders' Equity | $5M | $13M | $5M | $-15M | $-14M | $-7M | $-6M | $-9M | $-694.0K | $9M | $20M | $30M | $26M | $37M | $47M | $56M | |
| Liabilities + Equity | $19M | $30M | $20M | $28M | $29M | $39M | $41M | $42M | $50M | $62M | $77M | $90M | $84M | $95M | $109M | $123M | |
| Shares Outstanding | 1,949,041 | 39,978,693 | 12,928,853 | 12,733,853 | 10,708,393 | 10,462,250 | 8,487,818 | 6,020,259 | 5,904,278 | 5,894,085 | 5,894,085 | 5,885,313 | 99,344,798 | 96,617,898 | 4,830,464 | 96,398,360 |
Flujo de Efectivo 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $8.0K | $8.0K | $36.0K | $32.0K | $42.0K | $59.0K | $16.0K | $61.0K | $62.0K | $64.0K | $64.0K | $63.0K | $64.0K | $64.0K | $92.0K | $61.0K | |
| Stock-based Comp | $569.0K | $575.0K | $795.0K | $924.0K | $1M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $1M | $1M | $2M | $1M | |
| Operating Cash Flow | $-10M | $-9M | $-6M | $-6M | $-8M | $-7M | $-9M | $-6M | $-11M | $-13M | $-10M | $-8M | $-8M | $-12M | $-12M | $-13M | |
| CapEx | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | $0 | $52.0K | |
| Investing Cash Flow | $0 | $0 | $2M | $0 | $0 | $0 | $-428.0K | $18M | $-7M | $19M | $15M | $180.0K | $-3M | $26M | $3M | $4M | |
| Stock Issued | $-282.0K | $19M | $-119.0K | $6M | $-578.0K | $10M | $11M | $696.0K | $291.0K | $0 | $118.0K | $14M | $178.0K | $7.0K | $179.0K | · | |
| Net Stock Activity | · | $19M | · | · | · | $10M | · | · | · | $0 | · | · | · | · | · | · | |
| Financing Cash Flow | $-282.0K | $19M | $-119.0K | $4M | $-2M | $8M | $9M | $-2M | $-1M | $-2M | $-2M | $13M | $-852.0K | $-2M | $-1M | $5M | |
| Net Change in Cash | $-10M | $10M | $-4M | $-1M | $-10M | $285.0K | $-857.0K | $11M | $-20M | $3M | $2M | $5M | $-12M | $12M | $-10M | $-4M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | · | · | · | · | $-12M | · | · |
Rentabilidad 5
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | -218.0% | -300.1% | -426.8% | · | -360.5% | -491.4% | -597.8% | · | -436.6% | -552.5% | -506.2% | · | -446.2% | |
| Net Margin | · | · | · | -243.4% | -312.6% | -446.0% | · | -344.3% | -463.6% | -569.3% | · | -430.0% | -544.4% | -503.2% | · | -470.6% | |
| EBITDA Margin | · | · | · | -218.0% | -300.1% | -426.8% | · | -360.5% | -491.4% | -597.8% | · | -436.6% | -552.5% | -506.2% | · | -446.2% | |
| ROA | -35.6% | -70.1% | · | -22.1% | -21.6% | -20.9% | · | -15.2% | -17.5% | -15.2% | · | -11.5% | -11.2% | -9.8% | · | -9.0% | |
| ROE | 184.7% | -793.4% | · | 66.0% | 117.1% | -743.7% | · | -96.8% | -92.5% | -51.6% | · | -28.5% | -27.1% | -20.5% | · | -16.8% |
Liquidez y Solvencia 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 0.5 | 1.1 | · | 0.7 | 0.7 | 1.2 | · | 1.2 | 1.8 | 4.1 | · | 5.4 | 7.0 | 9.7 | · | 7.7 | |
| Quick Ratio | 0.4 | 1.0 | · | 0.6 | 0.7 | 1.1 | · | 1.1 | 1.6 | 3.8 | · | 5.2 | 6.8 | 9.2 | · | 7.4 | |
| Debt / Equity | · | · | · | -0.5 | -0.5 | -1.1 | · | · | · | · | · | · | · | · | · | · |
Eficiencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.1 | 0.1 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | |
| Receivables Turnover | · | · | · | 1.0 | 1.0 | 1.1 | · | 1.0 | 1.0 | 0.9 | · | 1.0 | 0.9 | 1.1 | · | 1.0 |
Valoración (TTM) 13
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $6M | $8M | · | $11M | $11M | $10M | · | $10M | $10M | $9M | · | $10M | $10M | $10M | · | $10M | |
| Net Income TTM | $-49M | $-51M | · | $-37M | $-41M | $-44M | · | $-46M | $-48M | $-48M | · | $-49M | $-53M | $-57M | · | $-56M | |
| Market Cap | $1M | $22M | · | $21M | $25M | $22M | · | $32M | $41M | $64M | · | $39M | $1.65B | $1.16B | · | $1.35B | |
| Enterprise Value | · | · | · | $19M | $22M | $9M | · | · | · | · | · | · | · | · | · | · | |
| P/E | -0.0 | -0.1 | · | -0.4 | -0.4 | -0.3 | · | -0.7 | -0.8 | -1.2 | · | -0.7 | -2.1 | -2.2 | · | -4.2 | |
| P/S | 0.2 | 2.6 | · | 1.9 | 2.3 | 2.2 | · | 3.1 | 4.2 | 6.8 | · | 3.8 | 169.8 | 121.1 | · | 130.8 | |
| P/B | 0.2 | 1.7 | · | -1.4 | -1.8 | -3.3 | · | -3.7 | -58.7 | 6.8 | · | 1.3 | 62.9 | 31.7 | · | 24.2 | |
| P / Tangible Book | · | 5.9 | · | · | · | · | · | · | · | 133.5 | · | 1.9 | 95.6 | 42.0 | · | 28.9 | |
| P / Cash Flow | · | -2.4 | · | · | · | -3.0 | · | · | · | -4.8 | · | · | · | -95.0 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | · | · | · | · | -95.0 | · | · | |
| EV / EBITDA | · | · | · | -2.7 | -2.7 | -0.9 | · | · | · | · | · | · | · | · | · | · | |
| EV / Revenue | · | · | · | 1.7 | 2.1 | 0.9 | · | · | · | · | · | · | · | · | · | · | |
| Earnings Yield | -3725.0% | -667.3% | · | -248.2% | -244.0% | -334.8% | · | -146.8% | -125.8% | -83.2% | · | -149.0% | -47.3% | -46.4% | · | -23.6% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $9M | $11M | $10M | $10M | $11M |
| Margen Operativo % | -60.5% | -408.3% | -482.2% | — | -395.0% |
| Beneficio neto | $-8M | $-43M | $-47M | $-57M | $-45M |
| EPS Diluido | $-0.58 | $-6.88 | $-8.96 | $-12.14 | $0.50 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Deuda / Patrimonio | 0.0 | -1.3 | — | — | 0.0 |
| Ratio corriente | 0.5 | 1.4 | 4.5 | — | 9.1 |
| Ratio Rápido | 0.4 | 1.2 | 4.4 | — | 8.9 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | — | — | $-38M | — | $-38M |
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Propietarios institucionales (13F) 39 declarantes · $7.0M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 9 (+1 vs trimestre anterior) | 12 (+4 vs trimestre anterior) | 5 (-8 vs trimestre anterior) | 7 (+1 vs trimestre anterior) | -3.9M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Bleichroeder LP | $1 985 196 | 3 802 329 | 28,49% | Acciones |
| Stonepine Capital Management, LLC | $1 729 292 | 3 312 185 | 24,82% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $1 033 717 | 98 996 | 14,84% | Acciones |
| Cable Car Capital, LP | $696 134 | 1 333 334 | 9,99% | Acciones |
| CM Management, LLC | $287 155 | 550 000 | 4,12% | Acciones |
| MORGAN STANLEY | $263 290 | 504 291 | 3,78% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $179 486 | 343 842 | 2,58% | Acciones |
| M28 Capital Management LP | $148 741 | 284 889 | 2,13% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $142 044 | 272 044 | 2,04% | Acciones |
| FLPUTNAM INVESTMENT MANAGEMENT CO | $128 306 | 245 750 | 1,84% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $74 123 | 141 972 | 1,06% | Acciones |
| VANGUARD GROUP INC | $60 862 | 61 664 | 0,87% | Acciones |
| XTX Topco Ltd | $56 470 | 108 160 | 0,81% | Acciones |
| NORTHERN TRUST CORP | $50 054 | 95 870 | 0,72% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $32 189 | 61 664 | 0,46% | Acciones |
| BlackRock, Inc. | $27 846 | 53 334 | 0,40% | Acciones |
| Focused Wealth Management, Inc | $26 131 | 50 049 | 0,38% | Acciones |
| STATE STREET CORP | $10 990 | 21 049 | 0,16% | Acciones |
| FRANKLIN STREET ADVISORS INC /NC | $10 442 | 20 000 | 0,15% | Acciones |
| LPL Financial LLC | $7 819 | 14 977 | 0,11% | Acciones |
| MAVERICK CAPITAL LTD | $6 194 | 49 554 | 0,09% | Acciones |
| Dauntless Investment Group, LLC | $5 222 | 10 001 | 0,07% | Acciones |
| BARCLAYS PLC | $3 641 | 6 973 | 0,05% | Acciones |
| Steward Partners Investment Advisory, LLC | $1 356 | 2 597 | 0,02% | Acciones |
| OSAIC HOLDINGS, INC. | $785 | 1 510 | 0,01% | Acciones |
| GROUP ONE TRADING LLC | $235 | 450 | 0,00% | Acciones |
| Axiom Investment Management LLC | $52 | 100 | 0,00% | Acciones |
| JPMORGAN CHASE & CO | $48 | 108 | 0,00% | Acciones |
| JONES FINANCIAL COMPANIES LLLP | $39 | 120 | 0,00% | Acciones |
| WELLS FARGO & COMPANY/MN | $29 | 55 | 0,00% | Acciones |
| CWM, LLC | $28 | 51 | 0,00% | Acciones |
| UBS Group AG | $16 | 31 | 0,00% | Acciones |
| GSA CAPITAL PARTNERS LLP | $12 | 22 760 | 0,00% | Acciones |
| CIBC Private Wealth Group LLC | $10 | 6 | 0,00% | Acciones |
| WR Wealth Planners, LLC | $3 | 1 | 0,00% | Acciones |
| Blue Trust, Inc. | $2 | 4 | 0,00% | Acciones |
| VIMA LLC | $2 | 3 | 0,00% | Acciones |
| MPWM ADVISORY SOLUTIONS, LLC | $1 | 2 | 0,00% | Acciones |
| ROYAL BANK OF CANADA | $0 | 63 | 0,00% | Acciones |
Informantes de la empresa 33 insiders · 17 directivos · 16 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| James E Dentzer | President & CEO | 7 de julio de 2026 A | 148 730 | 0 | 0 | $0 |
| Ali Fattaey Ph.D. | President & CEO | 15 de mayo de 2018 A | 322 140 | 0 | 0 | $0 |
| Diantha Duvall | CFO | 7 de julio de 2026 A | 77 707 | 0 | 0 | $0 |
| William Steinkrauss | Chief Financial Officer | 29 de enero de 2022 A | — | 0 | 0 | $0 |
| Michael Gray | CFO | 27 de mayo de 2015 A | 107 304 | 0 | 0 | $0 |
| Mitchell Keegan | Vice-President | 7 de enero de 2011 A | — | 0 | 0 | $0 |
| Jonathan B. Zung | CDO | 7 de julio de 2026 A | 66 667 | 0 | 0 | $0 |
| Ahmed Hamdy MD | CMO | 20 de marzo de 2026 C | 66 667 | 0 | 0 | $0 |
| Robert Martell | Head of Research & Development | 20 de enero de 2023 A | 23 027 | 0 | 0 | $0 |
| David Tuck | Chief Medical Officer | 15 de mayo de 2018 A | 169 424 | 0 | 0 | $0 |
| Mani Mohindru | Chief Strategy Officer | 14 de febrero de 2017 A | — | 0 | 0 | $0 |
| Jaye Viner | Chief Medical Officer | 27 de mayo de 2015 A | — | 0 | 0 | $0 |
| Mark Noel | VP, Tech Management | 2 de mayo de 2013 M | 27 540 | 0 | 0 | $0 |
| Changgeng Qian | VP, Research & Preclinical Dev | 7 de enero de 2011 A | — | 0 | 0 | $0 |
| Mary Elizabeth Potthoff | VP and General Counsel | 31 de mayo de 2006 A | 0 | 0 | 0 | $0 |
| Lee L Rubin | VP of Research | 1 de junio de 2005 A | 9 814 | 0 | 0 | $0 |
| Christopher U Missling | Sr. VP, Strategic Planning | 16 de enero de 2004 M | 0 | 0 | 0 | $0 |
| Anne Elizabeth Borgman | Consejero | 7 de julio de 2026 A | — | 0 | 0 | $0 |
| John Hohneker | Consejero | 7 de julio de 2026 A | — | 0 | 0 | $0 |
| Marc Rubin | Consejero | 7 de julio de 2026 A | 28 108 | 0 | 0 | $0 |
| Kenneth I Kaitin | Consejero | 7 de julio de 2026 A | 11 407 | 1 | 0 | $5 500 |
| Martyn D Greenacre | Consejero | 7 de julio de 2026 A | 26 089 | 0 | 0 | $0 |
| Lori Anne Kunkel | Consejero | 31 de enero de 2022 A | 22 200 | 0 | 0 | $0 |
| James R Mcnab | Consejero | 5 de mayo de 2017 S | 50 000 | 0 | 0 | $0 |
| Kenneth Pienta | Consejero | 28 de febrero de 2017 A | 30 000 | 0 | 0 | $0 |
| James R Tobin | Consejero | 26 de enero de 2015 A | 144 921 | 0 | 0 | $0 |
| Susan B Bayh | Consejero | 17 de enero de 2013 A | 25 000 | 0 | 0 | $0 |
| Joseph Davie MD PHD | Consejero | 7 de enero de 2011 A | — | 0 | 0 | $0 |
| Stephen Carter | Consejero | 25 de enero de 2008 A | — | 0 | 0 | $0 |
| Joseph M Davie | Consejero | 6 de junio de 2007 A | 20 000 | 0 | 0 | $0 |
| Douglas Melton | Consejero | 23 de agosto de 2006 A | 173 499 | 0 | 0 | $0 |
| Daniel R Passeri | — | 19 de enero de 2016 A | 211 798 | 0 | 0 | $0 |
| Maurizio Voi | — | 17 de enero de 2013 A | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 3 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Persona informante no revelada | 4 de marzo de 2004 | — | Presentación inicial | — | SEC |
| Persona informante no revelada | 29 de enero de 2004 | — | Presentación inicial | Inversión pasiva | SEC |
| Persona informante no revelada | 4 de junio de 2003 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 2 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.