FULC Fulcrum Therapeutics, Inc. - Common Stock
Acerca de Fulcrum Therapeutics, Inc. - Common Stock Descripción general de la empresa de Wikipedia
FULC Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
FULC Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
FULC Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 0 0,0%
- Compra 0 0,0%
- Mantener 7 58,3%
- Venta 3 25,0%
- Venta fuerte 2 16,7%
Precio objetivo a 12 meses
5 analistas · 2026-08-16Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.22 | $-0.22 | 0.00% |
| 31 de marzo de 2026 | $-0.25 | $-0.30 | 0.05% |
| 31 de diciembre de 2025 | $-0.31 | $-0.32 | 0.01% |
| 30 de septiembre de 2025 | $-0.31 | $-0.30 | -0.01% |
| 30 de junio de 2025 | $-0.28 | $-0.30 | 0.02% |
| 31 de marzo de 2025 | $-0.28 | $-0.30 | 0.02% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| FULC | $753M | -9.6 | 2752.0% | — | -26.6% | — |
| NMRA | $312M | -1.2 | — | — | -165.2% | — |
| TTRX | $116M | -32.8 | — | — | -141.7% | — |
| ANTX | $31M | -1.0 | — | — | -57.7% | — |
| SIGA | $438M | 19.1 | -31.8% | 24.6% | 11.4% | — |
| ORMP | $112M | 1.9 | -50.4% | 3202.5% | 37.0% | 0.65% |
| LLY | — | 46.8 | 44.7% | 31.7% | 101.2% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 12
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue | $0 | $80M | $3M | $6M | $19M | $9M | |
| R&D Expense | $56M | $63M | $72M | $77M | $70M | $59M | |
| SG&A Expense | $29M | $36M | $42M | $42M | $31M | $21M | |
| Operating Expenses | $85M | $102M | $113M | $119M | $100M | $80M | |
| Operating Income | $-85M | $-22M | $-111M | $-113M | $-81M | $-72M | |
| Income Tax | $0 | $0 | · | · | · | · | |
| Net Income | $-75M | $-10M | $-97M | $-110M | $-81M | $-71M | |
| EPS (Basic) | $-1.18 | $-0.16 | $-1.59 | $-2.44 | $-2.29 | $-2.79 | |
| EPS (Diluted) | $-1.18 | $-0.16 | $-1.59 | $-2.44 | $-2.29 | $-2.79 | |
| Shares (Basic) | 63,355 | 61,984 | 61,310 | 44,991 | 35,361 | 25,354 | |
| Shares (Diluted) | 63,355 | 61,984 | 61,310 | 44,991 | 35,361 | 25,354 | |
| EBITDA | $-85M | $-22M | $-111M | $-113M | · | $-72M |
Balance general 21
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $198M | $58M | $26M | $35M | $35M | $57M | |
| Prepaid Expense | $5M | $7M | $5M | $4M | $4M | $4M | |
| Other Current Assets | · | · | · | · | $0 | $74.0K | |
| Current Assets | $357M | $250M | $242M | $208M | $226M | $120M | |
| PP&E (Net) | $3M | $4M | $5M | $7M | $7M | $8M | |
| PP&E (Gross) | $18M | $18M | $18M | $18M | $16M | $15M | |
| Accum. Depreciation | $16M | $14M | $13M | $11M | $8M | $6M | |
| Other Non-current Assets | $538.0K | $10.0K | $2M | $2M | $542.0K | $578.0K | |
| Total Assets | $366M | $261M | $258M | $227M | $235M | $130M | |
| Accounts Payable | $2M | $1M | $3M | $4M | $5M | $4M | |
| Current Liabilities | $13M | $11M | $14M | $17M | $19M | $27M | |
| Capital Leases | $4M | $6M | $9M | $11M | $0 | · | |
| Other Non-current Liabilities | $197.0K | $197.0K | $197.0K | $197.0K | $0 | · | |
| Total Liabilities | $17M | $18M | $23M | $28M | $23M | $34M | |
| Common Stock | $67.0K | $54.0K | $62.0K | $52.0K | $41.0K | $28.0K | |
| Retained Earnings | $-594M | $-519M | $-510M | $-412M | $-302M | $-222M | |
| Treasury Stock | · | · | · | $0 | $0 | · | |
| AOCI | $174.0K | $130.0K | $-136.0K | $-797.0K | $-397.0K | $-2.0K | |
| Stockholders' Equity | $349M | $243M | $235M | $199M | $212M | $95M | |
| Liabilities + Equity | $366M | $261M | $258M | $227M | $235M | $130M | |
| Shares Outstanding | 66,578,891 | 53,968,303 | 61,915,367 | 52,099,211 | 40,626,224 | 27,941,566 |
Flujo de Efectivo 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $12M | $15M | $15M | $13M | $11M | $7M | |
| Restructuring | $400.0K | $2M | · | $400.0K | · | · | |
| Operating Cash Flow | $-60M | $-2M | $-91M | $-97M | $-78M | $-54M | |
| CapEx | $314.0K | $278.0K | $508.0K | $2M | $2M | $1M | |
| Investing Cash Flow | $31M | $32M | $-37M | $12M | $-130M | $-57M | |
| Stock Issued | $4M | $3M | $777.0K | $4M | $4M | $1M | |
| Net Stock Activity | $4M | $3M | $777.0K | $4M | · | $1M | |
| Financing Cash Flow | $169M | $3M | $118M | $84M | $187M | $71M | |
| Net Change in Cash | $139M | $33M | $-10M | $-314.0K | $-22M | $-40M | |
| Free Cash Flow | $-60M | $-2M | $-91M | $-99M | · | $-55M |
Rentabilidad 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Operating Margin | · | -27.4% | -3945.2% | -1774.8% | · | -811.6% | |
| Net Margin | · | -12.2% | -3470.0% | -1732.4% | · | -802.7% | |
| EBITDA Margin | · | -27.4% | -3945.2% | -1774.8% | · | -811.6% | |
| ROA | -23.9% | -3.8% | -40.2% | -47.6% | · | -59.0% | |
| ROE | -26.6% | -3.9% | -39.7% | -52.3% | · | -70.8% |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 27.4 | 22.6 | 17.7 | 12.4 | · | 4.5 | |
| Quick Ratio | 15.1 | 5.3 | 1.9 | 2.1 | · | 2.1 |
Eficiencia 1
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.3 | 0.0 | 0.0 | · | 0.1 |
Tasas de Crecimiento 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue YoY | · | 2752.0% | -55.8% | -66.9% | 117.2% | · | |
| Revenue CAGR 3Y | · | 61.0% | -31.8% | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue TTM | $0 | $80M | $3M | $6M | $19M | $9M | |
| Net Income TTM | $-75M | $-10M | $-97M | $-110M | $-81M | $-71M | |
| Market Cap | $753M | $254M | $418M | $379M | · | $327M | |
| P/E | -9.6 | -29.4 | -4.2 | -3.0 | -7.7 | -4.2 | |
| P/S | · | 3.2 | 149.0 | 59.8 | · | 37.1 | |
| P/B | 2.2 | 1.0 | 1.8 | 1.9 | · | 3.4 | |
| P / Tangible Book | 2.2 | 1.0 | 1.8 | 1.9 | 3.4 | 3.4 | |
| P / Cash Flow | -12.5 | -114.4 | -4.6 | -3.9 | · | -6.1 | |
| P / FCF | -12.5 | -101.6 | -4.6 | -3.8 | · | -5.9 | |
| Earnings Yield | -10.4% | -3.4% | -23.6% | -33.5% | -13.0% | -23.8% |
Estado de resultados 11
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | $0 | $0 | $0 | · | $0 | $0 | $80M | $0 | $871.0K | $759.0K | $880.0K | $295.0K | $685.0K | $1M | |
| R&D Expense | $12M | $14M | $15M | $14M | $13M | $13M | $12M | $15M | $17M | $20M | $19M | $18M | $18M | $17M | $19M | $15M | |
| SG&A Expense | $7M | $8M | $7M | $8M | $7M | $7M | $8M | $8M | $10M | $10M | $10M | $10M | $10M | $12M | $10M | $10M | |
| Operating Expenses | $29M | $22M | $23M | $22M | $20M | $20M | $19M | $25M | $28M | $30M | $29M | $28M | $28M | $28M | $29M | $26M | |
| Operating Income | $-29M | $-22M | $-23M | $-22M | $-20M | $-20M | $-19M | $-25M | $52M | $-30M | $-28M | $-27M | $-27M | $-28M | $-28M | $-24M | |
| Net Income | $-26M | $-19M | $-20M | $-20M | $-17M | $-18M | $-17M | $-22M | $55M | $-27M | $-25M | $-24M | $-24M | $-25M | $-26M | $-24M | |
| EPS (Basic) | $-0.34 | $-0.25 | $-0.31 | $-0.31 | $-0.28 | $-0.28 | $-0.27 | $-0.35 | $0.89 | $-0.43 | $-0.41 | $-0.39 | $-0.38 | $-0.41 | $-0.46 | $-0.51 | |
| EPS (Diluted) | $-0.34 | $-0.25 | $-0.31 | $-0.31 | $-0.28 | $-0.28 | $-0.25 | $-0.35 | $0.87 | $-0.43 | $-0.41 | $-0.39 | $-0.38 | $-0.41 | $-0.46 | $-0.51 | |
| Shares (Basic) | 76,264,000 | 76,215,000 | -187,556,645 | 62,597,000 | 62,544,000 | 62,479,000 | -186,536,016 | 62,409,000 | 62,205,000 | 61,984,000 | -123,615,412 | 61,823,000 | 61,794,000 | 59,722 | -82,756 | 46,213 | |
| Shares (Diluted) | 76,264,000 | 76,215,000 | -187,556,645 | 62,597,000 | 62,544,000 | 62,479,000 | -187,918,016 | 62,409,000 | 63,587,000 | 61,984,000 | -123,615,412 | 61,823,000 | 61,794,000 | 59,722 | -82,756 | 46,213 | |
| EBITDA | $-29M | $-22M | · | $-22M | $-20M | $-20M | · | $-25M | $52M | $-30M | · | $-27M | $-27M | $-28M | · | $-24M |
Balance general 21
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $48M | $50M | $198M | $47M | $43M | $42M | $58M | $73M | $87M | $40M | $26M | $30M | $34M | $35M | $35M | $91M | |
| Prepaid Expense | $4M | $5M | $5M | $5M | $5M | $5M | $7M | $7M | $4M | $5M | $5M | $5M | $4M | $5M | $4M | $5M | |
| Other Current Assets | · | · | · | · | $69.0K | · | · | · | · | · | · | · | · | · | · | · | |
| Current Assets | $323M | $339M | $357M | $206M | $219M | $233M | $250M | $267M | $280M | $218M | $242M | $262M | $283M | $303M | $208M | $228M | |
| PP&E (Net) | $0 | $2M | $3M | $3M | $3M | $4M | $4M | $4M | $4M | $5M | $5M | $6M | $6M | $7M | $7M | $7M | |
| PP&E (Gross) | $1M | $18M | $18M | $18M | $18M | $18M | $18M | $18M | $18M | $18M | $18M | $18M | $18M | $18M | $18M | $17M | |
| Accum. Depreciation | $1M | $15M | $16M | $15M | $15M | $15M | $14M | $14M | $14M | $13M | $13M | $12M | $12M | $11M | $11M | $10M | |
| Other Non-current Assets | $9.0K | $546.0K | $538.0K | $9.0K | $12.0K | $10.0K | $10.0K | $76.0K | $2M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Total Assets | $324M | $347M | $366M | $215M | $229M | $243M | $261M | $279M | $294M | $233M | $258M | $279M | $300M | $321M | $227M | $248M | |
| Accounts Payable | $3M | $2M | $2M | $3M | $2M | $2M | $1M | $4M | $4M | $4M | $3M | $4M | $4M | $4M | $4M | $3M | |
| Current Liabilities | $10M | $10M | $13M | $12M | $9M | $8M | $11M | $15M | $13M | $11M | $14M | $14M | $15M | $14M | $17M | $15M | |
| Capital Leases | $3M | $3M | $4M | $5M | $5M | $6M | $6M | $7M | $8M | $8M | $9M | $9M | $10M | $10M | $11M | $11M | |
| Other Non-current Liabilities | $197.0K | $197.0K | $197.0K | $197.0K | $197.0K | $197.0K | $197.0K | $197.0K | $197.0K | $197.0K | $197.0K | $197.0K | $447.0K | $320.0K | $197.0K | $197.0K | |
| Total Liabilities | $13M | $13M | $17M | $16M | $14M | $14M | $18M | $22M | $20M | $19M | $23M | $23M | $25M | $25M | $28M | $26M | |
| Common Stock | $76.0K | $67.0K | $67.0K | $54.0K | $54.0K | $54.0K | $54.0K | $54.0K | $62.0K | $62.0K | $62.0K | $62.0K | $62.0K | $62.0K | $52.0K | $52.0K | |
| Retained Earnings | $-639M | $-613M | $-594M | $-574M | $-554M | $-537M | $-519M | $-503M | $-481M | $-537M | $-510M | $-485M | $-461M | $-437M | $-412M | $-386M | |
| Treasury Stock | · | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | · | $0 | |
| AOCI | $-567.0K | $-513.0K | $174.0K | $241.0K | $82.0K | $70.0K | $130.0K | $379.0K | $-366.0K | $-434.0K | $-136.0K | $-886.0K | $-1M | $-651.0K | $-797.0K | $-921.0K | |
| Stockholders' Equity | $311M | $333M | $349M | $198M | $214M | $228M | $243M | $257M | $274M | $214M | $235M | $255M | $275M | $296M | $199M | $221M | |
| Liabilities + Equity | $324M | $347M | $366M | $215M | $229M | $243M | $261M | $279M | $294M | $233M | $258M | $279M | $300M | $321M | $227M | $248M | |
| Shares Outstanding | 76,285,157 | 66,608,096 | 66,578,891 | 54,108,438 | 54,091,588 | 53,979,306 | 53,968,303 | 53,938,661 | 62,250,631 | 62,141,011 | 61,915,367 | 52,099,211 | 52,099,211 | 61,758,994 | 52,099,211 | 52,049,913 |
Flujo de Efectivo 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $3M | $4M | $3M | $3M | $3M | $3M | $2M | $4M | $4M | $4M | $3M | $4M | $3M | $4M | $3M | $3M | |
| Restructuring | $4M | · | $400.0K | $0 | $0 | $0 | $2M | $0 | · | · | · | · | · | · | · | $400.0K | |
| Operating Cash Flow | $-16M | $-19M | $-17M | $-14M | $-14M | $-15M | $-17M | $-19M | $59M | $-25M | $-23M | $-23M | $-21M | $-24M | $-20M | $-28M | |
| CapEx | $108.0K | $8.0K | $159.0K | $90.0K | $65.0K | $0 | $231.0K | $19.0K | $0 | $28.0K | $77.0K | $65.0K | $195.0K | $171.0K | $116.0K | $283.0K | |
| Investing Cash Flow | $14M | $-128M | $-1M | $19M | $14M | $-777.0K | $2M | $4M | $-13M | $38M | $18M | $19M | $20M | $-94M | $-36M | $-2M | |
| Stock Issued | $356.0K | $21.0K | $4M | $64.0K | $301.0K | $0 | $83.0K | $635.0K | $377.0K | $2M | $287.0K | $0 | $142.0K | $348.0K | $267.0K | $93.0K | |
| Net Stock Activity | · | $21.0K | · | · | · | $0 | · | · | · | $2M | · | · | · | $348.0K | · | · | |
| Financing Cash Flow | $356.0K | $-312.0K | $168M | $64.0K | $301.0K | $0 | $83.0K | $635.0K | $377.0K | $2M | $287.0K | $0 | $142.0K | $118M | $218.0K | $81M | |
| Net Change in Cash | $-2M | $-147M | $150M | $4M | $414.0K | $-16M | $-14M | $-14M | $47M | $14M | $-5M | $-4M | $-768.0K | $-364.0K | $-56M | $51M | |
| Free Cash Flow | · | $-19M | · | · | · | $-15M | · | · | · | $-25M | · | · | · | $-24M | · | · |
Rentabilidad 5
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | · | · | · | · | · | · | · | · | 65.6% | · | · | -3615.3% | -3101.4% | -9471.2% | · | · | |
| Net Margin | · | · | · | · | · | · | · | · | 69.3% | · | · | -3164.3% | -2702.6% | -8399.7% | · | · | |
| EBITDA Margin | · | · | · | · | · | · | · | · | 65.6% | · | · | -3615.3% | -3101.4% | -9471.2% | · | · | |
| ROA | -9.5% | -6.4% | · | -7.9% | -6.6% | -7.4% | · | -7.8% | 22.6% | -10.1% | · | -9.1% | · | -9.2% | · | -9.4% | |
| ROE | -10.0% | -6.7% | · | -8.6% | -7.1% | -8.0% | · | -8.5% | 25.5% | -11.0% | · | -10.1% | · | -10.2% | · | -10.5% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 31.4 | 34.3 | · | 17.7 | 24.4 | 28.7 | · | 18.4 | 22.1 | 20.4 | · | 18.6 | · | 21.0 | · | 15.5 | |
| Quick Ratio | 4.7 | 5.1 | · | 4.0 | 4.7 | 5.2 | · | 5.0 | 6.8 | 3.7 | · | 2.1 | · | 2.4 | · | 6.2 |
Eficiencia 1
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | 0.0 | 0.0 | · | · | 0.0 | 0.3 | 0.0 | · | 0.0 | · | 0.0 | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | · | · | · | · | · | $81M | · | $81M | $82M | $2M | · | $3M | $4M | $6M | · | $11M | |
| Net Income TTM | $-82M | $-73M | · | $-76M | $-1M | $-11M | · | $-17M | $-19M | $-99M | · | $-96M | $-106M | $-109M | · | $-104M | |
| Market Cap | $279M | $511M | · | $498M | $372M | $155M | · | $193M | $386M | $587M | · | $231M | · | $176M | · | $421M | |
| P/E | -3.1 | -6.8 | · | -7.5 | -172.0 | -15.2 | · | -11.9 | -18.8 | -5.9 | · | -2.6 | -1.5 | -1.2 | · | -3.2 | |
| P/S | · | · | · | · | · | 1.9 | · | 2.4 | 4.7 | 303.3 | · | 74.2 | · | 29.6 | · | 39.8 | |
| P/B | 0.9 | 1.5 | · | 2.5 | 1.7 | 0.7 | · | 0.7 | 1.4 | 2.7 | · | 0.9 | · | 0.6 | · | 1.9 | |
| P / Tangible Book | 0.9 | 1.5 | · | 2.5 | 1.7 | 0.7 | · | 0.7 | 1.4 | 2.7 | · | 0.9 | · | 0.6 | · | 1.9 | |
| P / Cash Flow | · | -27.2 | · | · | · | -10.2 | · | · | · | -23.2 | · | · | · | -7.3 | · | · | |
| P / FCF | · | -27.2 | · | · | · | -10.2 | · | · | · | -23.2 | · | · | · | -7.2 | · | · | |
| Earnings Yield | -32.2% | -14.6% | · | -13.3% | -0.58% | -6.6% | · | -8.4% | -5.3% | -17.1% | · | -38.1% | -64.5% | -83.9% | · | -31.5% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $0 | $80M | $3M | $6M | $19M |
| Margen Operativo % | — | -27.4% | -3945.2% | -1774.8% | — |
| Beneficio neto | $-75M | $-10M | $-97M | $-110M | $-81M |
| EPS Diluido | $-1.18 | $-0.16 | $-1.59 | $-2.44 | $-2.29 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 27.4 | 22.6 | 17.7 | 12.4 | — |
| Ratio Rápido | 15.1 | 5.3 | 1.9 | 2.1 | — |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-60M | $-2M | $-91M | $-99M | — |
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Propietarios institucionales (13F) 169 declarantes · $235.0M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 35 (+2 vs trimestre anterior) | 39 (+3 vs trimestre anterior) | 67 (-4 vs trimestre anterior) | 34 (-6 vs trimestre anterior) | +4.1M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| EcoR1 Capital, LLC | $23 972 510 | 6 549 866 | 10,20% | Acciones |
| TANG CAPITAL MANAGEMENT LLC | $23 868 368 | 6 521 412 | 10,15% | Acciones |
| Nantahala Capital Management, LLC | $20 038 646 | 5 475 040 | 8,53% | Acciones |
| MONTANOVA CAPITAL, LLC | $13 472 171 | 3 680 921 | 5,73% | Acciones |
| CITADEL ADVISORS LLC | $9 898 488 | 2 704 505 | 4,21% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $9 871 811 | 2 697 216 | 4,20% | Acciones |
| D. E. Shaw & Co., Inc. | $8 099 115 | 2 212 873 | 3,45% | Acciones |
| STATE STREET CORP | $7 455 512 | 2 037 025 | 3,17% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $7 320 000 | 2 000 000 | 3,11% | Acciones |
| GSK plc | $6 535 713 | 1 785 714 | 2,78% | Acciones |
| Qube Research & Technologies Ltd | $6 399 389 | 1 748 467 | 2,72% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $6 030 948 | 1 647 800 | 2,57% | Acciones |
| ADAR1 Capital Management, LLC | $5 728 006 | 1 565 029 | 2,44% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $5 438 039 | 1 485 803 | 2,31% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $4 516 515 | 1 233 727 | 1,92% | Acciones |
| JANE STREET GROUP, LLC | $4 371 332 | 1 194 353 | 1,86% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $4 322 262 | 1 180 946 | 1,84% | Acciones |
| Ikarian Capital, LLC | $3 839 929 | 1 049 161 | 1,63% | Acciones |
| BANK OF AMERICA CORP /DE/ | $3 764 884 | 1 028 657 | 1,60% | Acciones |
| Jump Financial, LLC | $3 678 300 | 1 005 000 | 1,56% | Acciones |
| VANGUARD GROUP INC | $3 580 169 | 316 549 | 1,52% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $3 296 957 | 900 808 | 1,40% | Acciones |
| GOLDMAN SACHS GROUP INC | $3 163 389 | 864 314 | 1,35% | Acciones |
| Assenagon Asset Management S.A. | $3 056 847 | 835 204 | 1,30% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $2 974 724 | 812 766 | 1,27% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $2 862 647 | 782 144 | 1,22% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $2 727 860 | 745 317 | 1,16% | Acciones |
| Balyasny Asset Management L.P. | $2 534 082 | 692 372 | 1,08% | Acciones |
| BlackRock, Inc. | $2 504 769 | 684 363 | 1,07% | Acciones |
| Y-Intercept (Hong Kong) Ltd | $2 495 505 | 681 832 | 1,06% | Acciones |
| Point72 Asset Management, L.P. | $2 384 223 | 651 427 | 1,01% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 585 585 | 433 220 | 0,67% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $1 265 072 | 345 648 | 0,54% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $1 112 596 | 303 988 | 0,47% | Acciones |
| Peapod Lane Capital LLC | $1 046 021 | 285 798 | 0,45% | Acciones |
| Engineers Gate Manager LP | $885 720 | 242 000 | 0,38% | Acciones |
| EntryPoint Capital, LLC | $794 948 | 217 199 | 0,34% | Acciones |
| XTX Topco Ltd | $765 844 | 209 247 | 0,33% | Acciones |
| CITADEL ADVISORS LLC | $743 712 | 203 200 | 0,32% | Opción de venta |
| Quadrature Capital Ltd | $692 176 | 189 119 | 0,29% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $641 964 | 175 400 | 0,27% | Opción de venta |
| ALLIANCEBERNSTEIN L.P. | $639 448 | 83 370 | 0,27% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $570 477 | 155 868 | 0,24% | Acciones |
| Simplify Asset Management Inc. | $562 886 | 153 794 | 0,24% | Acciones |
| MARSHALL WACE, LLP | $500 860 | 136 847 | 0,21% | Acciones |
| Fiduciary Trust Co | $499 791 | 136 555 | 0,21% | Acciones |
| Squarepoint Ops LLC | $463 202 | 126 558 | 0,20% | Acciones |
| Verdad Advisers, LP | $458 320 | 125 224 | 0,19% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $435 679 | 119 038 | 0,19% | Acciones |
| HSBC HOLDINGS PLC | $426 477 | 109 353 | 0,18% | Acciones |
| Rangeley Capital, LLC | $420 497 | 114 890 | 0,18% | Acciones |
| CANADA PENSION PLAN INVESTMENT BOARD | $374 784 | 102 400 | 0,16% | Acciones |
| ALGERT GLOBAL LLC | $370 978 | 101 360 | 0,16% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $349 607 | 95 521 | 0,15% | Acciones |
| TWO SIGMA ADVISERS, LP | $344 955 | 30 500 | 0,15% | Acciones |
| FMR LLC | $337 917 | 92 327 | 0,14% | Acciones |
| Headlands Technologies LLC | $328 386 | 89 723 | 0,14% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $314 032 | 85 801 | 0,13% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $313 223 | 85 580 | 0,13% | Acciones |
| Matisse Capital | $304 108 | 39 649 | 0,13% | Acciones |
| BARCLAYS PLC | $300 757 | 82 174 | 0,13% | Acciones |
| AXQ CAPITAL, LP | $298 228 | 81 483 | 0,13% | Acciones |
| Allostery Investments LP | $277 629 | 40 353 | 0,12% | Acciones |
| RHUMBLINE ADVISERS | $268 793 | 73 443 | 0,11% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $263 520 | 72 000 | 0,11% | Opción de compra |
| RBF Capital, LLC | $256 200 | 70 000 | 0,11% | Acciones |
| PRELUDE CAPITAL MANAGEMENT, LLC | $248 357 | 67 857 | 0,11% | Acciones |
| ALPS ADVISORS INC | $247 533 | 67 632 | 0,11% | Acciones |
| CITIGROUP INC | $217 217 | 59 349 | 0,09% | Acciones |
| FOX RUN MANAGEMENT, L.L.C. | $206 592 | 56 446 | 0,09% | Acciones |
| DEUTSCHE BANK AG\ | $191 714 | 52 381 | 0,08% | Acciones |
| Bank of New York Mellon Corp | $189 357 | 51 737 | 0,08% | Acciones |
| WELLS FARGO & COMPANY/MN | $181 887 | 49 696 | 0,08% | Acciones |
| STRS OHIO | $169 092 | 46 200 | 0,07% | Acciones |
| JANE STREET GROUP, LLC | $161 772 | 44 200 | 0,07% | Opción de compra |
| COMMONWEALTH EQUITY SERVICES, LLC | $146 400 | 40 000 | 0,06% | Acciones |
| Marquette Asset Management, LLC | $141 101 | 38 552 | 0,06% | Acciones |
| Nuveen Asset Management, LLC | $136 624 | 29 069 | 0,06% | Acciones |
| MetLife Investment Management, LLC | $124 729 | 34 079 | 0,05% | Acciones |
| CITADEL ADVISORS LLC | $124 440 | 34 000 | 0,05% | Opción de compra |
| PROFUND ADVISORS LLC | $119 001 | 32 514 | 0,05% | Acciones |
| SEI INVESTMENTS CO | $112 292 | 30 681 | 0,05% | Acciones |
| COUNTRY TRUST BANK | $109 950 | 30 041 | 0,05% | Acciones |
| LMR Partners LLP | $109 800 | 30 000 | 0,05% | Acciones |
| AlphaQuest LLC | $109 232 | 9 658 | 0,05% | Acciones |
| Aigen Investment Management, LP | $108 014 | 29 512 | 0,05% | Acciones |
| Scientech Research LLC | $104 617 | 28 584 | 0,04% | Acciones |
| Mariner, LLC | $102 861 | 28 104 | 0,04% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $100 010 | 27 325 | 0,04% | Acciones |
| CWM, LLC | $92 761 | 12 094 | 0,04% | Acciones |
| Nuveen, LLC | $92 426 | 25 253 | 0,04% | Acciones |
| MORGAN STANLEY | $92 045 | 25 149 | 0,04% | Acciones |
| Graham Capital Management, L.P. | $91 745 | 25 067 | 0,04% | Acciones |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $91 690 | 25 052 | 0,04% | Acciones |
| FRANKLIN RESOURCES INC | $90 845 | 24 821 | 0,04% | Acciones |
| Rafferty Asset Management, LLC | $89 809 | 24 538 | 0,04% | Acciones |
| JANE STREET GROUP, LLC | $87 840 | 24 000 | 0,04% | Opción de venta |
| MERCER GLOBAL ADVISORS INC /ADV | $78 214 | 21 370 | 0,03% | Acciones |
| Invesco Ltd. | $74 664 | 20 400 | 0,03% | Acciones |
| Castleview Partners, LLC | $69 906 | 19 100 | 0,03% | Acciones |
Informantes de la empresa 29 insiders · 13 directivos · 13 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Alex Sapir | President & Chief Executive Officer | 2 de febrero de 2026 A | 193 360 | 0 | 0 | $0 |
| Bryan Stuart | President & Chief Executive Officer | 19 de enero de 2022 A | 0 | 0 | 0 | $0 |
| Esther Rajavelu | Chief Financial Officer | 9 de febrero de 2023 A | — | 0 | 0 | $0 |
| Judith Dunn | President, Research & Development | 19 de enero de 2022 A | — | 0 | 0 | $0 |
| Melvin H. Hayes III | Chief Operating Officer | 26 de abril de 2023 A | — | 0 | 0 | $0 |
| Greg Tourangeau | Principal Accounting Officer | 2 de febrero de 2026 A | 14 062 | 0 | 0 | $0 |
| Curtis Gale Oltmans | Chief Legal Officer | 2 de febrero de 2026 A | 10 252 | 0 | 1 | $-44 600 |
| Patrick Taylor Horn | Chief Medical Officer | 18 de marzo de 2024 A | — | 0 | 0 | $0 |
| Santiago Arroyo | Chief Medical Officer | 7 de noviembre de 2022 A | — | 0 | 0 | $0 |
| Christopher Morabito | Chief Medical Officer | 19 de enero de 2022 A | 1 100 | 0 | 0 | $0 |
| Christopher Moxham | Chief Scientific Officer | 10 de agosto de 2021 M | 0 | 0 | 0 | $0 |
| Owen B. Wallace | Chief Scientific Officer | 14 de septiembre de 2020 M | 133 438 | 0 | 0 | $0 |
| Diego Cadavid | SVP Clinical Development | 1 de julio de 2020 S | 65 714 | 0 | 0 | $0 |
| Sonja Banks | Consejero | 30 de junio de 2026 A | — | 0 | 0 | $0 |
| Alan Ezekowitz | Consejero | 30 de junio de 2026 A | 10 927 | 0 | 1 | $-65 700 |
| Colin Hill | Consejero | 30 de junio de 2026 A | — | 0 | 0 | $0 |
| Kate Haviland | Consejero | 30 de junio de 2026 A | — | 0 | 0 | $0 |
| Katina Dorton | Consejero | 30 de junio de 2026 A | — | 0 | 0 | $0 |
| Rachel K. King | Consejero | 30 de junio de 2026 A | — | 0 | 0 | $0 |
| Robert J Gould | Consejero | 30 de junio de 2026 A | 469 864 | 0 | 4 | $-667 350 |
| James A Geraghty | Consejero | 30 de junio de 2026 A | 90 714 | 0 | 0 | $0 |
| Joshua Lehrer-Graiwer | Consejero | 23 de abril de 2026 A | — | 0 | 0 | $0 |
| James J. Collins | Consejero | 17 de junio de 2024 A | — | 0 | 0 | $0 |
| Mark J Levin | Consejero | 10 de noviembre de 2021 J | 3 962 202 | 0 | 0 | $0 |
| 6 Dimensions Capital, L.P. | Propietario del 10% | 22 de julio de 2019 C | 559 821 | 0 | 0 | $0 |
| GSK plc | Propietario del 10% | 22 de julio de 2019 C | 1 785 714 | 0 | 0 | $0 |
| Sanofi | Propietario del 10% | 22 de julio de 2019 C | 558 035 | 0 | 0 | $0 |
| Alan A Musso | — | 2 de febrero de 2026 A | — | 0 | 0 | $0 |
| Peter G. Thomson | — | 19 de enero de 2022 A | 2 300 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Propiedad de ETFs Mantenido por 35 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| PILL · Direxion Shares ETF Trust | 0,59% | 10 748 NS | 30 de abril de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,41% | 21 230 NS | 30 de abril de 2026 | N-PORT |
| IWC · iShares Trust | 0,05% | 203 387 SH | 8 de agosto de 2026 | Diario |
| GSSC · Goldman Sachs ETF Trust | 0,04% | 53 140 NS | 31 de mayo de 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,04% | 140 971 NS | 31 de mayo de 2026 | N-PORT |
| BIB · ProShares Trust | 0,02% | 2 464 NS | 31 de mayo de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,02% | 3 588 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,02% | 411 384 SH | 8 de agosto de 2026 | Diario |
| IWN · iShares Trust | 0,01% | 562 208 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,01% | 25 920 NS | 30 de abril de 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,01% | 81 961 SH | 8 de agosto de 2026 | Diario |
| DFAS · Dimensional ETF Trust | 0,01% | 219 460 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,01% | 2 817 NS | 31 de mayo de 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,01% | 53 282 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,01% | 341 378 SH | 8 de agosto de 2026 | Diario |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 50 849 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,01% | 1 521 240 SH | 8 de agosto de 2026 | Diario |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 228 499 NS | 31 de mayo de 2026 | N-PORT |
| UWM · ProShares Trust | 0,01% | 2 203 NS | 31 de mayo de 2026 | N-PORT |
| URTY · ProShares Trust | 0,00% | 2 227 NS | 31 de mayo de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 1 960 NS | 30 de abril de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 2 209 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 56 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 3 000 NS | 30 de abril de 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 10 997 NS | 31 de mayo de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 7 834 NS | 30 de abril de 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 30 377 NS | 31 de mayo de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 110 458 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 23 143 SH | 8 de agosto de 2026 | Diario |
| DFUS · Dimensional ETF Trust | 0,00% | 10 048 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 15 348 NS | 30 de abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 553 375 SH | 8 de agosto de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 2 074 332 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 5 108 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,00% | 140 406 SH | 8 de agosto de 2026 | Diario |