GPCR Structure Therapeutics Inc. - American Depositary Shares
$53,70
Precio · Ago 19, 2026
Fundamentales a fecha de Ago 6, 2026
Rango 52S
$18–$95
46% of range
Calificación del Analista
BUY
23 analysts
Precio Objetivo
$105
+96% upside
P/E (TTM)
-67.1
ROE
-12.3%
Margen de Beneficio Neto
—
GPCR Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$53.70
Capitalización Bursátil
$11.41B
P/E (TTM)
-67.1
BPA (TTM)
$-0.80
Ingresos (TTM)
—
Rendimiento div.
—
ROE
-12.3%
Deuda/Capital
—
Rango 52S
$18 – $95
GPCR Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
—
BPA
$-0.80
2022-12-31
→
2025-12-31
Flujo de caja libre
$-226M
2023-12-31
→
2025-12-31
Márgenes
—
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
GPCR
Mediana de Pares
P/E (TTM)
-67.1
38.7
P/B (P/C)
7.5
3.8
Price / FCF (Precio / FCF)
-50.5
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
GPCR
Mediana de Pares
ROA
-11.3%
-6.4%
ROE
-12.3%
-16.8%
ROIC
-11.7%
—
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
GPCR
Mediana de Pares
Current Ratio (Ratio corriente)
24.8
12.8
Quick Ratio (Ratio Rápido)
22.9
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
GPCR
Mediana de Pares
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
GPCR
Mediana de Pares
GPCR Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
23 analistas
- Compra fuerte 8 34,8%
- Compra 13 56,5%
- Mantener 2 8,7%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
15 analistas · 2026-08-14
Mediana
$104.00
← Por Debajo de Todos los Objetivos
$53.70
Mín
$69.50
Máx
$145.00
Objetivo mediano
$104.00
+93,7%
Objetivo medio
$105.10
+95,7%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
-0.49%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.49 | $-0.41 | -0.08% |
| 31 de marzo de 2026 | $-0.35 | $-0.35 | 0.00% |
| 31 de diciembre de 2025 | $-1.22 | $-0.47 | -0.75% |
| 30 de septiembre de 2025 | $-1.11 | $-0.36 | -0.75% |
| 30 de junio de 2025 | $-1.08 | $-0.28 | -0.80% |
| 31 de marzo de 2025 | $-0.81 | $-0.23 | -0.58% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| MANE | — | — | — | — | 82.6% | — |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| AMLX | $1.33B | -7.9 | -77.1% | — | -61.2% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
| MBX | $1.42B | -13.3 | — | — | -29.6% | — |
| ALMS | — | -3.4 | — | -1011.8% | -61.9% | — |
| TARS | $3.48B | -51.5 | 146.7% | -14.7% | -19.7% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 12
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| R&D Expense | $225M | $109M | $70M | $36M | |
| SG&A Expense | $62M | $49M | $33M | $16M | |
| Operating Expenses | $177M | $158M | $103M | $53M | |
| Operating Income | $-177M | $-158M | $-103M | $-53M | |
| Pretax Income | $-141M | $-122M | $-89M | $-51M | |
| Income Tax | $515.0K | $310.0K | $236.0K | $17.0K | |
| Net Income | $-141M | $-123M | $-90M | $-51M | |
| EPS (Basic) | $-0.80 | $-0.78 | $-0.81 | $-5.51 | |
| EPS (Diluted) | $-0.80 | $-0.78 | $-0.81 | $-5.51 | |
| Shares (Basic) | 177,596,000 | 157,922,000 | 110,198,000 | 9,584,000 | |
| Shares (Diluted) | 177,596,000 | 157,922,000 | 110,198,000 | 9,584,000 | |
| EBITDA | $-177M | $-158M | $-103M | · |
Balance general 21
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $800M | $170M | $130M | $26M | |
| Short-term Investments | $647M | $714M | $338M | $65M | |
| Prepaid Expense | $24M | $8M | $6M | $2M | |
| Current Assets | $1.57B | $891M | $474M | $93M | |
| PP&E (Net) | $7M | $3M | $3M | $1M | |
| PP&E (Gross) | $10M | $5M | $4M | $1M | |
| Accum. Depreciation | $3M | $2M | $644.0K | $349.0K | |
| Other Non-current Assets | $717.0K | $5M | $45.0K | $3M | |
| Total Assets | $1.58B | $903M | $482M | $98M | |
| Accounts Payable | $14M | $8M | $5M | $6M | |
| Current Liabilities | $63M | $36M | $25M | $13M | |
| Capital Leases | $4M | $2M | $4M | · | |
| Other Non-current Liabilities | $647.0K | $302.0K | $298.0K | · | |
| Total Liabilities | $68M | $38M | $29M | $13M | |
| Common Stock | $21.0K | $17.0K | $14.0K | $1.0K | |
| Paid-in Capital | $1.99B | $1.19B | $659M | $2M | |
| Retained Earnings | $-470M | $-329M | $-207M | $-117M | |
| AOCI | $1M | $914.0K | $521.0K | $-110.0K | |
| Stockholders' Equity | $1.52B | $865M | $453M | $-115M | |
| Liabilities + Equity | $1.58B | $903M | $482M | $98M | |
| Shares Outstanding | 212,513,000 | 171,860,000 | 139,220,000 | 10,527,000 |
Flujo de Efectivo 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $29M | $19M | $8M | $3M | |
| Operating Cash Flow | $-222M | $-117M | $-79M | $-46M | |
| CapEx | $4M | $1M | $2M | $155.0K | |
| Investing Cash Flow | $90M | $-359M | $-268M | $-62M | |
| Stock Issued | · | $515M | · | · | |
| Net Stock Activity | · | $515M | · | · | |
| Financing Cash Flow | $763M | $515M | $452M | $29M | |
| Net Change in Cash | $630M | $40M | $104M | $-79M | |
| Taxes Paid | $634.0K | $370.0K | $12.0K | · | |
| Free Cash Flow | $-226M | $-118M | $-82M | · |
Rentabilidad 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| ROA | -11.3% | -17.7% | -30.9% | · | |
| ROE | -12.3% | -13.9% | -27.8% | · | |
| ROIC | -11.7% | -18.3% | -22.8% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 24.8 | 24.7 | 19.1 | · | |
| Quick Ratio | 22.9 | 24.5 | 18.9 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Net Income TTM | $-141M | $-123M | $-90M | $-51M | |
| Market Cap | $14.78B | $4.66B | $5.67B | · | |
| P/E | -86.9 | -34.8 | -50.3 | · | |
| P/B | 9.7 | 5.4 | 12.5 | · | |
| P / Tangible Book | 9.7 | 5.4 | 12.5 | · | |
| P / Cash Flow | -66.5 | -40.0 | -71.4 | · | |
| P / FCF | -65.5 | -39.5 | -69.5 | · | |
| Earnings Yield | -1.1% | -2.9% | -2.0% | · |
Estado de resultados 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $100M | $67M | $69M | $59M | $55M | $43M | $33M | $33M | $22M | $21M | $18M | $19M | $13M | $8M | $10M | $8M | |
| SG&A Expense | $19M | $23M | $18M | $15M | $16M | $13M | $14M | $13M | $11M | $11M | $9M | $7M | $7M | $5M | $4M | $4M | |
| Operating Expenses | $119M | $89M | $-24M | $74M | $70M | $56M | $47M | $46M | $33M | $32M | $26M | $26M | $20M | $13M | $14M | $13M | |
| Operating Income | $-119M | $-89M | $24M | $-74M | $-70M | $-56M | $-47M | $-46M | $-33M | $-32M | $-26M | $-26M | $-20M | $-13M | $-14M | $-13M | |
| Pretax Income | $-106M | $-76M | $33M | $-66M | $-62M | $-47M | $-36M | $-34M | $-26M | $-26M | $-23M | $-23M | $-18M | $-12M | $-14M | $-13M | |
| Income Tax | $234.0K | $190.0K | $170.0K | $108.0K | $139.0K | $98.0K | $136.0K | $92.0K | $53.0K | $29.0K | $405.0K | $118.0K | $25.0K | $-180.0K | $64.0K | $60.0K | |
| Net Income | $-106M | $-76M | $33M | $-66M | $-62M | $-47M | $-36M | $-34M | $-26M | $-26M | $-24M | $-23M | $-18M | $-12M | $-14M | $-13M | |
| EPS (Basic) | $-0.49 | $-0.35 | $0.20 | $-0.37 | $-0.36 | $-0.27 | $-0.21 | $-0.20 | $-0.18 | $-0.19 | $-0.21 | $-0.20 | $-0.25 | $-1.16 | $-1.64 | $-1.44 | |
| EPS (Diluted) | $-0.49 | $-0.35 | $0.20 | $-0.37 | $-0.36 | $-0.27 | $-0.21 | $-0.20 | $-0.18 | $-0.19 | $-0.21 | $-0.20 | $-0.25 | $-1.16 | $-1.64 | $-1.44 | |
| Shares (Basic) | 217,957,000 | 217,326,000 | -342,571,000 | 175,469,000 | 172,647,000 | 172,051,000 | -301,657,000 | 171,630,000 | 148,239,000 | 139,710,000 | 114,948,000 | 114,759,000 | 71,655,000 | -18,694,000 | 9,435,000 | 9,063,000 | |
| Shares (Diluted) | 217,957,000 | 217,326,000 | 4,194,000 | 175,469,000 | 172,647,000 | 172,051,000 | -301,657,000 | 171,630,000 | 148,239,000 | 139,710,000 | 114,948,000 | 114,759,000 | 71,655,000 | -18,694,000 | 9,435,000 | 9,063,000 | |
| EBITDA | $-119M | $-89M | · | $-74M | $-70M | $-56M | · | $-46M | $-33M | $-32M | $-26M | $-26M | $-20M | · | · | · |
Balance general 21
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $273M | $316M | $800M | $103M | $147M | $152M | $170M | $172M | $382M | $98M | $51M | $41M | $126M | $26M | · | · | |
| Short-term Investments | $1.07B | $1.14B | $647M | $696M | $639M | $685M | $714M | $743M | $545M | $339M | $155M | $184M | $114M | $65M | · | · | |
| Prepaid Expense | $29M | $32M | $24M | $15M | $13M | $13M | $8M | $8M | $11M | $13M | $5M | $4M | $5M | $2M | · | · | |
| Current Assets | $1.37B | $1.49B | $1.57B | $814M | $799M | $850M | $891M | $924M | $938M | $449M | $210M | $228M | $246M | $93M | · | · | |
| PP&E (Net) | $6M | $6M | $7M | $5M | $3M | $4M | $3M | $4M | $3M | $3M | $2M | $1M | $961.0K | $1M | · | · | |
| PP&E (Gross) | · | · | $10M | · | · | · | $5M | $5M | $4M | $4M | $3M | $2M | $1M | $1M | · | · | |
| Accum. Depreciation | · | · | $3M | · | · | · | $2M | $1M | $1M | $866.0K | $572.0K | $493.0K | $419.0K | $349.0K | · | · | |
| Other Non-current Assets | $41M | $6M | $717.0K | $7M | $6M | $6M | $5M | $2M | $2M | $47.0K | $350.0K | $38.0K | $59.0K | $3M | · | · | |
| Total Assets | $1.43B | $1.51B | $1.58B | $832M | $816M | $867M | $903M | $933M | $947M | $457M | $216M | $229M | $247M | $98M | · | · | |
| Accounts Payable | $11M | $8M | $14M | $18M | $9M | $9M | $8M | $8M | $2M | $7M | $3M | $6M | $5M | $6M | · | · | |
| Current Liabilities | $66M | $57M | $63M | $58M | $39M | $36M | $36M | $33M | $23M | $24M | $20M | $15M | $11M | $13M | · | · | |
| Capital Leases | $4M | $3M | $4M | $4M | $5M | $5M | $2M | $3M | $3M | $4M | $3M | · | · | · | · | · | |
| Other Non-current Liabilities | $1M | $863.0K | $647.0K | $325.0K | $317.0K | $308.0K | $302.0K | $309.0K | $293.0K | $296.0K | $281.0K | · | · | · | · | · | |
| Total Liabilities | $71M | $61M | $68M | $62M | $44M | $42M | $38M | $36M | $26M | $27M | $23M | $15M | $11M | $13M | · | · | |
| Common Stock | $21.0K | $21.0K | $21.0K | $18.0K | $17.0K | $17.0K | $17.0K | $17.0K | $17.0K | $14.0K | · | · | $11.0K | $1.0K | · | · | |
| Paid-in Capital | $2.01B | $2.00B | $1.99B | $1.27B | $1.21B | $1.20B | $1.19B | $1.19B | $1.18B | $663M | $375M | $373M | $371M | $2M | · | · | |
| Retained Earnings | $-652M | $-546M | $-470M | $-503M | $-438M | $-376M | $-329M | $-293M | $-259M | $-233M | $-182M | $-158M | $-135M | $-117M | · | · | |
| AOCI | $-3M | $-2M | $1M | $825.0K | $362.0K | $815.0K | $914.0K | $3M | $-487.0K | $-90.0K | $-310.0K | $-390.0K | $147.0K | $-110.0K | · | · | |
| Stockholders' Equity | $1.35B | $1.45B | $1.52B | $770M | $772M | $825M | $865M | $897M | $921M | $430M | $193M | $214M | $236M | $-115M | · | · | |
| Liabilities + Equity | $1.43B | $1.51B | $1.58B | $832M | $816M | $867M | $903M | $933M | $947M | $457M | $216M | $229M | $247M | $98M | · | · | |
| Shares Outstanding | 213,655,000 | 213,208,000 | 212,513,000 | 182,033,000 | 172,700,000 | 172,610,000 | 171,860,000 | 171,762,000 | 171,589,000 | 139,855,000 | · | · | 114,730,000 | 10,527,000 | · | · |
Flujo de Efectivo 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $13M | $12M | $8M | $7M | $8M | $6M | $6M | $6M | $4M | $3M | $2M | $2M | $3M | $623.0K | $643.0K | $620.0K | |
| Operating Cash Flow | $-120M | $15M | $-64M | $-51M | $-55M | $-52M | $-36M | $-20M | $-26M | $-34M | $-21M | $-17M | $-20M | $-12M | $-10M | $-14M | |
| CapEx | $-42.0K | $1M | $1M | $2M | $232.0K | $314.0K | $16.0K | $685.0K | $427.0K | $162.0K | $820.0K | · | · | $71.0K | $-53.0K | $65.0K | |
| Investing Cash Flow | $74M | $-497M | $56M | $-49M | $49M | $34M | $33M | $-189M | $-205M | $1M | $30M | $-69M | $-49M | $10M | $-16M | $-40M | |
| Stock Issued | · | · | · | · | · | · | · | $0 | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $2M | $-2M | $705M | $56M | $517.0K | $809.0K | $615.0K | $-757.0K | $515M | $702.0K | $473.0K | $-297.0K | $170M | $-316.0K | $31M | $-1M | |
| Net Change in Cash | $-44M | $-483M | $697M | $-44M | $-5M | $-17M | $-3M | $-209M | $284M | $-32M | $10M | $-86M | $100M | $-2M | $5M | $-55M | |
| Free Cash Flow | · | $14M | · | · | · | $-53M | · | · | · | $-34M | · | · | · | · | · | · |
Rentabilidad 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -9.5% | -6.4% | · | -7.4% | -7.0% | -7.1% | · | -5.9% | -4.4% | -7.4% | -22.1% | · | -14.5% | · | · | · | |
| ROE | -10.0% | -6.7% | · | -7.9% | -7.3% | -7.5% | · | -6.2% | -4.6% | -7.8% | -24.7% | · | -15.2% | · | · | · | |
| ROIC | -8.8% | -6.2% | · | -9.6% | -9.2% | -6.8% | · | -5.1% | -3.6% | -7.5% | -13.8% | -12.2% | -8.3% | · | · | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 20.8 | 26.2 | · | 14.2 | 20.5 | 23.3 | · | 27.6 | 41.4 | 19.1 | 10.5 | 15.2 | 22.4 | · | · | · | |
| Quick Ratio | 20.3 | 25.6 | · | 13.9 | 20.1 | 22.9 | · | 27.4 | 40.9 | 18.5 | 10.2 | 15.0 | 21.9 | · | · | · |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-310M | $-250M | · | $-208M | $-169M | $-133M | · | $-110M | $-99M | $-91M | $-78M | $-68M | $-57M | · | · | · | |
| Market Cap | $11.47B | $10.28B | · | $5.10B | $3.58B | $2.99B | · | $7.54B | $6.74B | $5.99B | · | · | $2.73B | · | · | · | |
| P/E | -34.2 | · | · | · | -24.7 | -20.6 | · | -56.3 | -50.3 | -50.4 | -26.1 | -12.4 | -5.2 | · | · | · | |
| P/B | 8.5 | 7.1 | · | 6.6 | 4.6 | 3.6 | · | 8.4 | 7.3 | 13.9 | · | · | 11.5 | · | · | · | |
| P / Tangible Book | 8.5 | 7.1 | · | 6.6 | 4.6 | 3.6 | · | 8.4 | 7.3 | 13.9 | · | · | 11.5 | · | · | · | |
| P / Cash Flow | · | 674.6 | · | · | · | -57.2 | · | · | · | -175.9 | · | · | -134.4 | · | · | · | |
| P / FCF | · | 731.3 | · | · | · | -56.9 | · | · | · | -175.1 | · | · | · | · | · | · | |
| Earnings Yield | -2.9% | · | · | · | -4.0% | -4.9% | · | -1.8% | -2.0% | -2.0% | -3.8% | -8.1% | -19.3% | · | · | · |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Beneficio neto | $-141M | $-123M | $-90M | $-51M |
| EPS Diluido | $-0.80 | $-0.78 | $-0.81 | $-5.51 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Ratio corriente | 24.8 | 24.7 | 19.1 | — |
| Ratio Rápido | 22.9 | 24.5 | 18.9 | — |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Flujo de caja libre | $-226M | $-118M | $-82M | — |
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Propietarios institucionales (13F) 206 declarantes · $2.9B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 33 (-6 vs trimestre anterior) | 28 (-10 vs trimestre anterior) | 71 (+3 vs trimestre anterior) | 58 (-9 vs trimestre anterior) | -476K |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | $351 836 637 | 6 555 555 | 12,00% | Acciones |
| FMR LLC | $345 296 142 | 6 433 690 | 11,78% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $340 675 263 | 6 347 592 | 11,62% | Acciones |
| Deep Track Capital, LP | $254 399 664 | 4 740 072 | 8,68% | Acciones |
| BVF INC/IL | $180 697 390 | 3 366 823 | 6,16% | Acciones |
| ORBIMED ADVISORS LLC | $118 578 498 | 2 209 400 | 4,05% | Acciones |
| PRINCIPAL FINANCIAL GROUP INC | $94 070 254 | 1 752 753 | 3,21% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $90 282 956 | 1 682 179 | 3,08% | Acciones |
| RTW INVESTMENTS, LP | $86 274 901 | 1 607 507 | 2,94% | Acciones |
| Driehaus Capital Management LLC | $83 361 264 | 1 553 219 | 2,84% | Acciones |
| BAKER BROS. ADVISORS LP | $76 883 831 | 1 432 529 | 2,62% | Acciones |
| Casdin Capital, LLC | $63 062 250 | 1 175 000 | 2,15% | Acciones |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $58 285 620 | 1 086 000 | 1,99% | Acciones |
| CAPITOLIS LIQUID GLOBAL MARKETS LLC | $55 875 837 | 1 041 100 | 1,91% | Acciones |
| Siren, L.L.C. | $46 852 139 | 872 967 | 1,60% | Acciones |
| Pacific Heights Asset Management LLC | $42 936 000 | 800 000 | 1,46% | Acciones |
| Rock Springs Capital Management LP | $34 365 813 | 640 317 | 1,17% | Acciones |
| Aberdeen Group plc | $34 344 238 | 639 915 | 1,17% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $29 484 326 | 611 708 | 1,01% | Acciones |
| Logos Global Management LP | $26 835 000 | 500 000 | 0,92% | Acciones |
| Parkman Healthcare Partners LLC | $26 065 426 | 485 661 | 0,89% | Acciones |
| Davern Capital Partners, LP | $23 939 987 | 446 059 | 0,82% | Acciones |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $22 476 996 | 418 800 | 0,77% | Acciones |
| DEUTSCHE BANK AG\ | $17 811 302 | 331 867 | 0,61% | Acciones |
| NEXTBio Capital Management LP | $16 771 660 | 312 496 | 0,57% | Acciones |
| Catalio Capital Management, LP | $14 842 438 | 276 550 | 0,51% | Acciones |
| MARSHALL WACE, LLP | $14 361 663 | 267 592 | 0,49% | Acciones |
| HSG Holding Ltd | $13 672 433 | 254 750 | 0,47% | Acciones |
| SEB Asset Management AB | $13 151 433 | 245 043 | 0,45% | Acciones |
| BANK OF AMERICA CORP /DE/ | $12 579 336 | 234 383 | 0,43% | Acciones |
| GOLDMAN SACHS GROUP INC | $12 520 889 | 233 294 | 0,43% | Acciones |
| NATIONAL BANK OF CANADA /FI/ | $11 581 986 | 215 800 | 0,40% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $10 957 053 | 204 156 | 0,37% | Acciones |
| Eversept Partners, LP | $10 535 528 | 196 302 | 0,36% | Acciones |
| Schonfeld Strategic Advisors LLC | $10 234 062 | 190 685 | 0,35% | Acciones |
| Woodline Partners LP | $8 254 875 | 153 808 | 0,28% | Acciones |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $8 218 000 | 153 119 | 0,28% | Acciones |
| ArrowMark Colorado Holdings LLC | $8 081 575 | 150 579 | 0,28% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $7 994 039 | 148 948 | 0,27% | Acciones |
| CenterBook Partners LP | $7 944 770 | 148 030 | 0,27% | Acciones |
| Rhenman & Partners Asset Management AB | $7 787 517 | 145 100 | 0,27% | Acciones |
| GOLDMAN SACHS GROUP INC | $7 782 150 | 145 000 | 0,27% | Opción de compra |
| B Group, Inc. | $7 513 800 | 140 000 | 0,26% | Acciones |
| HighVista Strategies LLC | $7 019 177 | 130 784 | 0,24% | Acciones |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $6 745 728 | 125 689 | 0,23% | Acciones |
| Squarepoint Ops LLC | $6 739 610 | 125 575 | 0,23% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6 566 202 | 122 344 | 0,22% | Acciones |
| D. E. Shaw & Co., Inc. | $6 188 151 | 115 300 | 0,21% | Acciones |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $6 027 141 | 112 300 | 0,21% | Acciones |
| Soleus Capital Management, L.P. | $5 742 690 | 107 000 | 0,20% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5 302 596 | 98 800 | 0,18% | Opción de compra |
| Avidity Partners Management LP | $5 259 660 | 98 000 | 0,18% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $5 215 811 | 97 183 | 0,18% | Acciones |
| Qube Research & Technologies Ltd | $5 012 939 | 93 403 | 0,17% | Acciones |
| PEREGRINE CAPITAL MANAGEMENT LLC | $4 949 930 | 92 229 | 0,17% | Acciones |
| PFM Health Sciences, LP | $4 913 489 | 91 550 | 0,17% | Acciones |
| PLATINUM INVESTMENT MANAGEMENT LTD | $4 849 782 | 90 363 | 0,17% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $4 807 115 | 89 568 | 0,16% | Acciones |
| ExodusPoint Capital Management, LP | $4 200 536 | 78 266 | 0,14% | Acciones |
| Boxer Capital Management, LLC | $4 025 250 | 75 000 | 0,14% | Acciones |
| Cormorant Asset Management, LP | $4 025 250 | 75 000 | 0,14% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4 025 250 | 75 000 | 0,14% | Acciones |
| CITADEL ADVISORS LLC | $4 014 516 | 74 800 | 0,14% | Opción de compra |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3 869 607 | 72 100 | 0,13% | Opción de venta |
| ALPS ADVISORS INC | $3 855 277 | 71 833 | 0,13% | Acciones |
| TD Asset Management Inc | $3 701 191 | 68 962 | 0,13% | Acciones |
| Point72 Europe (London) LLP | $3 267 516 | 116 697 | 0,11% | Acciones |
| Brevan Howard Capital Management LP | $3 258 144 | 60 336 | 0,11% | Acciones |
| Burkehill Global Management, LP | $3 220 200 | 60 000 | 0,11% | Acciones |
| JANE STREET GROUP, LLC | $3 026 988 | 56 400 | 0,10% | Opción de compra |
| CITADEL ADVISORS LLC | $2 908 914 | 54 200 | 0,10% | Opción de venta |
| TUDOR INVESTMENT CORP ET AL | $2 879 718 | 53 656 | 0,10% | Acciones |
| ANTIPODES PARTNERS Ltd | $2 751 232 | 51 262 | 0,09% | Acciones |
| SCOGGIN MANAGEMENT LP | $2 683 500 | 50 000 | 0,09% | Opción de compra |
| Buckland Partners Management Co LLC | $2 683 500 | 50 000 | 0,09% | Acciones |
| SEVEN GRAND MANAGERS, LLC | $2 683 500 | 50 000 | 0,09% | Acciones |
| DAFNA Capital Management LLC | $2 495 655 | 46 500 | 0,09% | Acciones |
| Mariner, LLC | $2 484 116 | 46 285 | 0,08% | Acciones |
| STATE STREET CORP | $2 395 238 | 44 629 | 0,08% | Acciones |
| VOYA INVESTMENT MANAGEMENT LLC | $2 383 485 | 44 410 | 0,08% | Acciones |
| BANQUE PICTET & CIE SA | $2 325 628 | 43 332 | 0,08% | Acciones |
| Jump Financial, LLC | $2 289 455 | 42 658 | 0,08% | Acciones |
| Cinctive Capital Management LP | $2 193 869 | 40 877 | 0,07% | Acciones |
| Jefferies Financial Group Inc. | $2 180 344 | 40 625 | 0,07% | Acciones |
| Jones Hill Capital LP | $2 177 231 | 40 567 | 0,07% | Acciones |
| AMERIPRISE FINANCIAL INC | $2 117 656 | 39 457 | 0,07% | Acciones |
| OSAIC HOLDINGS, INC. | $2 115 279 | 39 414 | 0,07% | Acciones |
| STEMPOINT CAPITAL LP | $2 049 013 | 38 178 | 0,07% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2 045 256 | 38 108 | 0,07% | Acciones |
| CAPITAL FUND MANAGEMENT S.A. | $2 000 871 | 37 281 | 0,07% | Acciones |
| PSquared Asset Management AG | $1 996 524 | 37 200 | 0,07% | Acciones |
| FLAX POND CAPITAL, LLC | $1 932 120 | 36 000 | 0,07% | Acciones |
| TrueMark Investments, LLC | $1 803 312 | 33 600 | 0,06% | Acciones |
| NOMURA ASSET MANAGEMENT CO LTD | $1 759 839 | 32 790 | 0,06% | Acciones |
| DCF Advisers, LLC | $1 722 807 | 32 100 | 0,06% | Acciones |
| EXCHANGE TRADED CONCEPTS, LLC | $1 651 587 | 30 773 | 0,06% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $1 534 962 | 28 600 | 0,05% | Acciones |
| Verition Fund Management LLC | $1 530 615 | 28 519 | 0,05% | Acciones |
| Y-Intercept (Hong Kong) Ltd | $1 479 843 | 27 573 | 0,05% | Acciones |
| Seven Fleet Capital Management LP | $1 441 572 | 26 800 | 0,05% | Acciones |
Informantes de la empresa 15 insiders · 4 directivos · 8 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Raymond C Stevens | Chief Executive Officer | 7 de febrero de 2023 P | — | 0 | 0 | $0 |
| Jun Yoon | Chief Financial Officer | 7 de febrero de 2023 P | — | 0 | 0 | $0 |
| Mark Allen Bach | Chief Medical Officer | 7 de febrero de 2023 P | — | 0 | 0 | $0 |
| Melita Sun Jung | Chief Business Officer | 7 de febrero de 2023 P | — | 0 | 0 | $0 |
| Joanne Waldstreicher | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Angus C. Russell | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Sharon Tetlow | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Daniel G Welch | Consejero | 17 de junio de 2026 A | 123 508 | 0 | 0 | $0 |
| Eric Dobmeier | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Ted W Love | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Ramy Farid | Consejero | 7 de febrero de 2023 P | 3 260 495 | 0 | 0 | $0 |
| FMR LLC | Propietario del 10% | 22 de julio de 2026 S | 4 769 404 | 0 | 22 | $-7 057 088 |
| John Joseph Berrios | — | 6 de agosto de 2026 A | 140 766 | 0 | 0 | $0 |
| Xichen Lin | — | 4 de agosto de 2026 S | 228 960 | 0 | 5 | $-983 084 |
| FIL Ltd | — | 7 de febrero de 2023 C | 624 239 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Propiedad de ETFs Mantenido por 14 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1,78% | 73 020 NS | 31 de mayo de 2026 | N-PORT |
| MID · AMERICAN CENTURY ETF TRUST | 0,70% | 17 825 NS | 31 de mayo de 2026 | N-PORT |
| FDG · AMERICAN CENTURY ETF TRUST | 0,57% | 59 428 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,46% | 4 115 NS | 30 de abril de 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 0,44% | 4 628 NS | 31 de mayo de 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,35% | 4 583 NS | 31 de mayo de 2026 | N-PORT |
| GDOC · Goldman Sachs ETF Trust | 0,20% | 1 008 NS | 31 de mayo de 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,19% | 2 531 NS | 31 de mayo de 2026 | N-PORT |
| BIB · ProShares Trust | 0,15% | 2 880 NS | 31 de mayo de 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,13% | 40 344 NS | 30 de abril de 2026 | N-PORT |
| APIE · Trust for Professional Managers | 0,02% | 4 104 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 20 734 NS | 31 de mayo de 2026 | N-PORT |
| IBB · iShares Trust | — | — | 18 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | — | — | 20 de julio de 2026 | Diario |