HOWL Werewolf Therapeutics, Inc. - Common Stock
$0,41
Precio · Ago 19, 2026
Fundamentales a fecha de Jul 31, 2026
Rango 52S
$0–$2
7% of range
Calificación del Analista
STRONG BUY
10 analysts
Precio Objetivo
$7
+1602% upside
P/E (TTM)
-0.3
ROE
-183.6%
Margen de Beneficio Neto
—
HOWL Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$0.41
Capitalización Bursátil
$20M
P/E (TTM)
-0.3
BPA (TTM)
$-1.33
Ingresos (TTM)
—
Rendimiento div.
—
ROE
-183.6%
Deuda/Capital
1.1
Rango 52S
$0 – $2
HOWL Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
—
BPA
$-1.33
2020-12-31
→
2025-12-31
Flujo de caja libre
$-60M
2021-12-31
→
2025-12-31
Márgenes
—
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
HOWL
Mediana de Pares
P/E (TTM)
-0.3
—
P/B (P/C)
0.8
3.3
EV / EBITDA
0.1
—
Price / FCF (Precio / FCF)
-0.3
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
HOWL
Mediana de Pares
ROA
-62.0%
-66.0%
ROE
-183.6%
-128.2%
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
HOWL
Mediana de Pares
Debt / Equity (Deuda / Patrimonio)
1.1
1.0
Current Ratio (Ratio corriente)
1.6
2.6
Quick Ratio (Ratio Rápido)
1.6
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
HOWL
Mediana de Pares
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
HOWL
Mediana de Pares
HOWL Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
10 analistas
- Compra fuerte 4 40,0%
- Compra 4 40,0%
- Mantener 2 20,0%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
1 analistas · 2026-08-18
Mín
$7.00
Máx
$7.00
Objetivo mediano
$7.00
+1601,5%
Objetivo medio
$7.00
+1601,5%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.09%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $0.08 | $-0.27 | 0.35% |
| 31 de marzo de 2026 | $-0.28 | $-0.29 | 0.01% |
| 31 de diciembre de 2025 | $-0.17 | $-0.35 | 0.18% |
| 30 de septiembre de 2025 | $-0.36 | $-0.40 | 0.04% |
| 30 de junio de 2025 | $-0.40 | $-0.49 | 0.09% |
| 31 de marzo de 2025 | $-0.40 | $-0.40 | 0.00% |
| 31 de diciembre de 2024 | $-0.46 | $-0.43 | -0.03% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| HOWL | $31M | -0.5 | — | — | -183.6% | — |
| ALLR | $17M | -0.0 | — | -3509.7% | -102.1% | — |
| MRKR | $25M | -1.9 | -46.2% | -343.0% | -89.1% | — |
| NEUP | $14M | -30.9 | — | -2.4% | -2.3% | — |
| CYCN | — | -1.1 | 3.7% | — | — | — |
| KALA | $15M | -0.2 | — | — | -1423.8% | — |
| TPST | $14M | -0.5 | — | — | -319.3% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $45M | $56M | $42M | $54M | $35M | $17M | |
| SG&A Expense | $16M | $19M | $19M | $19M | $15M | $6M | |
| Operating Expenses | $61M | $75M | $60M | $72M | $50M | $22M | |
| Operating Income | $-61M | $-74M | $-41M | $-56M | $-50M | $-22M | |
| Interest Expense | · | · | $3M | $0 | · | · | |
| Interest Income | $3M | $7M | $7M | $2M | · | · | |
| Other Non-op | $2M | $2M | $-1M | $338.0K | $104.0K | $7M | |
| Income Tax | $0 | · | · | · | · | · | |
| Net Income | $-61M | $-71M | $-37M | $-54M | $-50M | $-15M | |
| EPS (Basic) | $-1.32 | $-1.63 | $-1.05 | $-1.86 | $-10.94 | $-28.08 | |
| EPS (Diluted) | $-1.33 | $-1.63 | $-1.05 | $-1.86 | $-10.94 | $-28.08 | |
| Shares (Basic) | 46,018,888 | 43,332,088 | 35,646,572 | 28,863,935 | 18,455,000 | 1,005,000 | |
| Shares (Diluted) | 46,810,252 | 43,859,664 | 35,646,572 | 28,863,935 | 18,455,000 | 1,005,000 | |
| EBITDA | $-61M | $-74M | $-41M | $-56M | $-50M | · |
Balance general 23
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $57M | $111M | $134M | $129M | $158M | $93M | |
| Prepaid Expense | $2M | $2M | $3M | $4M | $4M | $344.0K | |
| Current Assets | $59M | $113M | $138M | $140M | $161M | $93M | |
| PP&E (Net) | $5M | $6M | $8M | $9M | $3M | $651.0K | |
| PP&E (Gross) | $11M | $11M | $11M | $10M | $3M | $826.0K | |
| Accum. Depreciation | · | · | · | · | $391.0K | · | |
| Other Non-current Assets | $5.0K | $320.0K | $594.0K | $1M | $649.0K | $0 | |
| Total Assets | $69M | $127M | $175M | $160M | $179M | $96M | |
| Accounts Payable | $754.0K | $3M | $1M | $1M | $2M | $1M | |
| Accrued Liabilities | $5M | $11M | $9M | $14M | $9M | $4M | |
| Short-term Debt | $28M | $0 | $7M | $0 | · | · | |
| Current Liabilities | $36M | $15M | $19M | $24M | $12M | $5M | |
| Capital Leases | $8M | $9M | $11M | $13M | $15M | $2M | |
| Other Non-current Liabilities | · | · | $0 | $191.0K | $0 | $31.0K | |
| Total Liabilities | $45M | $54M | $63M | $38M | $26M | $7M | |
| Long-term Debt | $32M | $32M | $40M | · | · | · | |
| Total Debt | $28M | $0 | $7M | · | · | · | |
| Common Stock | $5.0K | $5.0K | $4.0K | $3.0K | $2.0K | $2.0K | |
| Paid-in Capital | $500M | $488M | $455M | $429M | $406M | $0 | |
| Retained Earnings | $-475M | $-415M | $-344M | $-307M | $-253M | $-52M | |
| Stockholders' Equity | $25M | $73M | $111M | $122M | $153M | $-52M | |
| Liabilities + Equity | $69M | $127M | $175M | $160M | $179M | $96M | |
| Shares Outstanding | 48,596,817 | 44,827,159 | 39,107,048 | 31,515,074 | 27,313,000 | 1,184,000 |
Flujo de Efectivo 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $6M | $9M | $8M | $7M | $4M | $632.0K | |
| Deferred Tax | $0 | $0 | $0 | $0 | $0 | $0 | |
| Operating Cash Flow | $-60M | $-56M | $-33M | $-41M | $-43M | $-19M | |
| CapEx | $0 | $254.0K | $769.0K | $4M | $498.0K | $560.0K | |
| Investing Cash Flow | $0 | $-254.0K | $-769.0K | $-4M | $-498.0K | $-560.0K | |
| Stock Issued | $6M | $24M | $18M | $16M | $0 | · | |
| Net Stock Activity | $6M | $24M | $18M | $16M | · | · | |
| Financing Cash Flow | $6M | $13M | $58M | $16M | $109M | $94M | |
| Net Change in Cash | $-54M | $-43M | $25M | $-28M | $66M | $75M | |
| Free Cash Flow | $-60M | $-56M | $-33M | $-44M | $-43M | · |
Rentabilidad 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -62.0% | -46.7% | -22.3% | -31.7% | -36.3% | · | |
| ROE | -183.6% | -86.6% | -33.4% | -42.5% | -31.0% | · |
Liquidez y Solvencia 4
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 1.6 | 7.4 | 7.1 | 5.8 | 13.6 | · | |
| Quick Ratio | 1.6 | 7.3 | 6.9 | 5.4 | 13.3 | · | |
| Debt / Equity | 1.1 | 0.0 | 0.1 | · | · | · | |
| Interest Coverage | · | · | -12.9 | · | · | · |
Valoración (TTM) 11
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-61M | $-71M | $-37M | $-54M | $-50M | · | |
| Market Cap | $31M | $66M | $151M | $64M | $325M | · | |
| Enterprise Value | $2M | $-45M | $23M | · | · | · | |
| P/E | -0.5 | -0.9 | -3.7 | -1.1 | -1.1 | · | |
| P/B | 1.2 | 0.9 | 1.4 | 0.5 | 2.1 | · | |
| P / Tangible Book | 1.2 | 0.9 | 1.4 | 0.5 | 2.1 | · | |
| P / Cash Flow | -0.5 | -1.2 | -4.6 | -1.6 | -7.6 | · | |
| P / FCF | -0.5 | -1.2 | -4.5 | -1.5 | -7.5 | · | |
| EV / EBITDA | -0.0 | 0.6 | -0.6 | · | · | · | |
| EV / FCF | -0.0 | 0.8 | -0.7 | · | · | · | |
| Earnings Yield | -209.8% | -110.1% | -27.2% | -90.7% | -91.9% | · |
Estado de resultados 13
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $6M | $8M | $7M | $12M | $13M | $13M | $16M | $13M | $15M | $13M | $10M | $11M | $10M | $12M | $16M | $13M | |
| SG&A Expense | $8M | $5M | $2M | $4M | $4M | $5M | $5M | $5M | $5M | $5M | $5M | $4M | $5M | $5M | $5M | $4M | |
| Operating Expenses | $14M | $13M | $9M | $16M | $18M | $18M | $20M | $17M | $20M | $18M | $14M | $15M | $14M | $17M | $20M | $18M | |
| Operating Income | $7M | $-13M | $-9M | $-16M | $-18M | $-18M | $-20M | $-17M | $-19M | $-17M | $-13M | $-9M | $-6M | $-12M | $-13M | $-13M | |
| Interest Expense | · | · | · | · | · | · | · | · | · | $1M | · | · | · | $172.0K | · | · | |
| Interest Income | $277.0K | $433.0K | $564.0K | $697.0K | $850.0K | $997.0K | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | · | · | |
| Other Non-op | $64.0K | $674.0K | $2M | $0 | $11.0K | $168.0K | $-94.0K | $97.0K | $2M | $-1.0K | $-6.0K | $-5.0K | $-25.0K | $-1M | $70.0K | $3.0K | |
| Net Income | $4M | $-14M | $-8M | $-16M | $-18M | $-18M | $-20M | $-17M | $-17M | $-16M | $-12M | $-8M | $-5M | $-12M | $-12M | $-12M | |
| EPS (Basic) | $0.08 | $-0.28 | $-0.16 | $-0.36 | $-0.40 | $-0.40 | $-0.46 | $-0.38 | $-0.40 | $-0.39 | $-0.34 | $-0.23 | $-0.14 | $-0.34 | $-0.37 | $-0.40 | |
| EPS (Diluted) | $0.08 | $-0.28 | $-0.17 | $-0.36 | $-0.40 | $-0.40 | $-0.43 | $-0.38 | $-0.43 | $-0.39 | $-0.34 | $-0.23 | $-0.14 | $-0.34 | $-0.37 | $-0.40 | |
| Shares (Basic) | 48,597,534 | 48,596,817 | -89,594,059 | 45,804,042 | 44,981,746 | 44,827,159 | -85,501,433 | 43,704,836 | 43,521,406 | 41,607,279 | -70,349,735 | 35,653,924 | 35,557,701 | 34,784,682 | -55,810,065 | 29,764,000 | |
| Shares (Diluted) | 48,597,534 | 49,388,181 | -88,802,695 | 45,804,042 | 44,981,746 | 44,827,159 | -85,495,635 | 43,704,836 | 44,043,184 | 41,607,279 | -70,349,735 | 35,653,924 | 35,557,701 | 34,784,682 | -55,810,065 | 29,764,000 | |
| EBITDA | $7M | $-13M | · | $-16M | $-18M | $-18M | · | $-17M | $-19M | $-17M | · | $-9M | $-6M | $-12M | · | $-13M |
Balance general 23
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $22M | $46M | $57M | $66M | $78M | $92M | $111M | $123M | $135M | $139M | $134M | $130M | $137M | $148M | $129M | $140M | |
| Prepaid Expense | $905.0K | $2M | $2M | $2M | $3M | $2M | $2M | $3M | $3M | $2M | $3M | $3M | $3M | $2M | $4M | $7M | |
| Current Assets | $23M | $49M | $59M | $68M | $80M | $94M | $113M | $126M | $139M | $142M | $138M | $139M | $147M | $157M | $140M | $152M | |
| PP&E (Net) | $1M | $4M | $5M | $5M | $5M | $6M | $6M | $7M | $7M | $8M | $8M | $8M | $8M | $9M | $9M | $9M | |
| PP&E (Gross) | · | · | $11M | · | · | · | $11M | · | · | · | $11M | · | · | · | $10M | $10M | |
| Accum. Depreciation | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $992.0K | |
| Other Non-current Assets | $0 | $0 | $5.0K | $46.0K | $122.0K | $179.0K | $320.0K | $42.0K | $265.0K | $248.0K | $594.0K | $516.0K | $652.0K | $670.0K | $1M | $2M | |
| Total Assets | $24M | $58M | $69M | $80M | $93M | $107M | $127M | $140M | $154M | $178M | $175M | $176M | $185M | $195M | $160M | $172M | |
| Accounts Payable | $2M | $4M | $754.0K | $1M | $3M | $986.0K | $3M | $1M | $1M | $2M | $1M | $1M | $1M | $2M | $1M | $1M | |
| Accrued Liabilities | $6M | $5M | $5M | $9M | $9M | $9M | $11M | $10M | $9M | $6M | $9M | $8M | $10M | $13M | $14M | $14M | |
| Short-term Debt | $0 | $29M | $28M | $6M | $2M | · | $0 | $0 | $0 | $12M | $7M | $2M | · | · | $0 | · | |
| Current Liabilities | $8M | $39M | $36M | $18M | $15M | $12M | $15M | $12M | $11M | $21M | $19M | $14M | $15M | $22M | $24M | $28M | |
| Capital Leases | $0 | $7M | $8M | $8M | $9M | $9M | $9M | $10M | $10M | $11M | $11M | $11M | $12M | $12M | $13M | $13M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | · | $0 | $0 | $0 | $191.0K | $191.0K | |
| Total Liabilities | $8M | $46M | $45M | $50M | $51M | $50M | $54M | $51M | $50M | $60M | $63M | $64M | $67M | $74M | $38M | $41M | |
| Long-term Debt | · | $32M | $32M | $32M | $32M | $32M | · | $32M | $32M | $40M | · | · | · | · | · | · | |
| Total Debt | $0 | $29M | · | $6M | $2M | · | · | $0 | $0 | $12M | · | $2M | · | · | · | · | |
| Common Stock | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $502M | $501M | $500M | $497M | $492M | $490M | $488M | $484M | $482M | $478M | $455M | $445M | $442M | $440M | $429M | $426M | |
| Retained Earnings | $-485M | $-489M | $-475M | $-467M | $-451M | $-433M | $-415M | $-394M | $-378M | $-360M | $-344M | $-332M | $-324M | $-319M | $-307M | $-295M | |
| Stockholders' Equity | $16M | $12M | $25M | $30M | $41M | $57M | $73M | $89M | $104M | $118M | $111M | $112M | $119M | $121M | $122M | $131M | |
| Liabilities + Equity | $24M | $58M | $69M | $80M | $93M | $107M | $127M | $140M | $154M | $178M | $175M | $176M | $185M | $195M | $160M | $172M | |
| Shares Outstanding | 48,599,066 | 48,596,817 | 48,596,817 | 47,273,685 | 45,335,265 | 44,827,159 | 44,827,159 | 43,721,772 | 43,702,147 | 43,282,371 | 39,107,048 | 35,658,000 | 35,642,000 | 35,301,000 | 31,433,731 | 30,611,000 |
Flujo de Efectivo 9
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $419.0K | $929.0K | $1M | $1M | $2M | $2M | $2M | $2M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Operating Cash Flow | $7M | $-11M | $-11M | $-15M | $-15M | $-19M | $-14M | $-12M | $-14M | $-15M | $-5M | $-7M | $-11M | $-10M | $-12M | $-14M | |
| CapEx | · | · | $0 | $0 | $0 | $0 | $123.0K | $3.0K | $17.0K | $111.0K | $198.0K | $221.0K | $182.0K | $168.0K | $518.0K | $2M | |
| Investing Cash Flow | · | · | $0 | $0 | $0 | $0 | $-123.0K | $-3.0K | $-17.0K | $-111.0K | $-198.0K | $-221.0K | $-182.0K | $-168.0K | $-518.0K | $-2M | |
| Stock Issued | · | · | $2M | $3M | $347.0K | $0 | $2M | $-29.0K | $877.0K | $20M | $9M | $-84.0K | $552.0K | $9M | $979.0K | $11M | |
| Net Stock Activity | · | · | · | · | · | $0 | · | · | · | $20M | · | · | · | $9M | · | · | |
| Financing Cash Flow | · | · | $2M | $3M | $388.0K | $0 | $3M | $-6.0K | $-10M | $20M | $9M | $41.0K | $692.0K | $49M | $1M | $11M | |
| Net Change in Cash | $-25M | $-11M | $-9M | $-12M | $-15M | $-19M | $-12M | $-12M | $-24M | $5M | $4M | $-7M | $-10M | $39M | $-11M | $-5M | |
| Free Cash Flow | · | · | · | · | · | $-19M | · | · | · | $-15M | · | · | · | $-10M | · | · |
Rentabilidad 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | 6.3% | -16.4% | · | -14.9% | -14.6% | -12.7% | · | -10.5% | -10.2% | -8.7% | · | -4.8% | -2.8% | -6.7% | · | -6.8% | |
| ROE | 12.7% | -38.9% | · | -27.5% | -24.7% | -20.7% | · | -16.5% | -15.5% | -13.6% | · | -6.8% | -4.1% | -9.2% | · | -8.0% |
Liquidez y Solvencia 4
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.9 | 1.3 | · | 3.9 | 5.3 | 8.1 | · | 10.1 | 12.1 | 6.7 | · | 9.6 | 9.8 | 7.2 | · | 5.5 | |
| Quick Ratio | 2.8 | 1.2 | · | 3.7 | 5.1 | 7.9 | · | 9.9 | 11.8 | 6.6 | · | 9.0 | 9.2 | 6.8 | · | 5.1 | |
| Debt / Equity | 0.0 | 2.4 | · | 0.2 | 0.1 | · | · | 0.0 | 0.0 | 0.1 | · | 0.0 | · | · | · | · | |
| Interest Coverage | · | · | · | · | · | · | · | · | · | -17.1 | · | · | · | · | · | · |
Valoración (TTM) 11
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-44M | $-66M | · | $-69M | $-70M | $-68M | · | $-58M | $-47M | $-42M | · | $-37M | $-44M | $-54M | · | $-56M | |
| Market Cap | $17M | $40M | · | $93M | $49M | $44M | · | $93M | $107M | $280M | · | $76M | $109M | $92M | · | $138M | |
| Enterprise Value | $-4M | $23M | · | $33M | $-26M | · | · | $-30M | $-29M | $153M | · | $-52M | · | · | · | · | |
| P/E | -0.4 | -0.6 | · | -1.3 | -0.7 | -0.6 | · | -1.5 | -2.1 | -5.9 | · | -1.9 | -2.2 | -1.4 | · | -2.3 | |
| P/B | 1.1 | 3.3 | · | 3.1 | 1.2 | 0.8 | · | 1.0 | 1.0 | 2.4 | · | 0.7 | 0.9 | 0.8 | · | 1.1 | |
| P / Tangible Book | 1.1 | 3.3 | · | 3.1 | 1.2 | 0.8 | · | 1.0 | 1.0 | 2.4 | · | 0.7 | 0.9 | 0.8 | · | 1.1 | |
| P / Cash Flow | · | -3.8 | · | · | · | -2.3 | · | · | · | -18.3 | · | · | · | -9.3 | · | · | |
| P / FCF | · | · | · | · | · | -2.3 | · | · | · | -18.2 | · | · | · | -9.1 | · | · | |
| EV / EBITDA | -0.6 | -1.7 | · | -2.1 | 1.5 | · | · | 1.8 | 1.5 | -8.9 | · | 5.6 | · | · | · | · | |
| EV / FCF | · | · | · | · | · | · | · | · | · | -9.9 | · | · | · | · | · | · | |
| Earnings Yield | -266.7% | -172.9% | · | -78.2% | -147.7% | -164.6% | · | -67.5% | -48.8% | -17.0% | · | -51.9% | -46.2% | -70.4% | · | -44.4% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-61M | $-71M | $-37M | $-54M | $-50M |
| EPS Diluido | $-1.33 | $-1.63 | $-1.05 | $-1.86 | $-10.94 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Deuda / Patrimonio | 1.1 | 0.0 | 0.1 | — | — |
| Ratio corriente | 1.6 | 7.4 | 7.1 | 5.8 | 13.6 |
| Ratio Rápido | 1.6 | 7.3 | 6.9 | 5.4 | 13.3 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-60M | $-56M | $-33M | $-44M | $-43M |
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Propietarios institucionales (13F) 54 declarantes · $12.4M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 13 (+3 vs trimestre anterior) | 11 (0 vs trimestre anterior) | 9 (+2 vs trimestre anterior) | 8 (-3 vs trimestre anterior) | -3.3M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| MPM ASSET MANAGEMENT LLC | $8 490 424 | 4 309 860 | 68,38% | Acciones |
| RA CAPITAL MANAGEMENT, L.P. | $859 349 | 2 387 744 | 6,92% | Acciones |
| Balyasny Asset Management L.P. | $644 253 | 1 790 089 | 5,19% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $438 471 | 1 217 976 | 3,53% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $242 800 | 674 632 | 1,96% | Acciones |
| Lynx1 Capital Management LP | $236 737 | 657 786 | 1,91% | Acciones |
| SPHERA FUNDS MANAGEMENT LTD. | $225 589 | 626 810 | 1,82% | Acciones |
| DC Funds, LP | $212 018 | 589 102 | 1,71% | Acciones |
| Verdad Advisers, LP | $125 500 | 348 709 | 1,01% | Acciones |
| VANGUARD GROUP INC | $113 948 | 179 728 | 0,92% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $98 563 | 273 764 | 0,79% | Acciones |
| XTX Topco Ltd | $97 705 | 271 478 | 0,79% | Acciones |
| Cubist Systematic Strategies, LLC | $92 020 | 46 711 | 0,74% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $56 781 | 157 726 | 0,46% | Acciones |
| JANE STREET GROUP, LLC | $52 752 | 146 573 | 0,42% | Acciones |
| STATE STREET CORP | $42 889 | 119 168 | 0,35% | Acciones |
| Squarepoint Ops LLC | $37 157 | 103 242 | 0,30% | Acciones |
| Rangeley Capital, LLC | $35 990 | 100 000 | 0,29% | Acciones |
| Nuveen Asset Management, LLC | $31 557 | 21 322 | 0,25% | Acciones |
| NORTHERN TRUST CORP | $31 258 | 86 851 | 0,25% | Acciones |
| Alyeska Investment Group, L.P. | $31 151 | 86 554 | 0,25% | Acciones |
| MPM BIOIMPACT LLC | $28 851 | 80 142 | 0,23% | Acciones |
| CITADEL ADVISORS LLC | $26 993 | 75 000 | 0,22% | Opción de compra |
| Point72 Asia (Singapore) Pte. Ltd. | $25 642 | 13 016 | 0,21% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $22 334 | 62 055 | 0,18% | Acciones |
| H D Vest Advisory Services | $11 118 | 10 200 | 0,09% | Acciones |
| BlackRock, Inc. | $10 661 | 29 623 | 0,09% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $9 825 | 27 300 | 0,08% | Acciones |
| StoneX Group Inc. | $9 000 | 20 000 | 0,07% | Acciones |
| BANK OF AMERICA CORP /DE/ | $8 331 | 23 206 | 0,07% | Acciones |
| GOLDMAN SACHS GROUP INC | $7 206 | 20 023 | 0,06% | Acciones |
| TWO SIGMA ADVISERS, LP | $6 525 | 10 300 | 0,05% | Acciones |
| CITADEL ADVISORS LLC | $5 578 | 15 500 | 0,04% | Opción de venta |
| CERTUITY, LLC | $5 399 | 15 000 | 0,04% | Acciones |
| HBK Sorce Advisory LLC | $5 317 | 13 227 | 0,04% | Acciones |
| BARCLAYS PLC | $4 763 | 13 235 | 0,04% | Acciones |
| Larson Financial Group LLC | $4 697 | 13 052 | 0,04% | Acciones |
| LPL Financial LLC | $4 244 | 11 791 | 0,03% | Acciones |
| Ranch Capital Advisors Inc. | $3 959 | 11 000 | 0,03% | Acciones |
| Marest Capital, LLC | $3 912 | 10 870 | 0,03% | Acciones |
| Cetera Investment Advisers | $3 671 | 10 200 | 0,03% | Acciones |
| Tower Research Capital LLC (TRC) | $3 562 | 9 897 | 0,03% | Acciones |
| OSAIC HOLDINGS, INC. | $3 087 | 8 575 | 0,02% | Acciones |
| Financial Perspectives, Inc | $2 429 | 6 750 | 0,02% | Acciones |
| MORGAN STANLEY | $678 | 1 885 | 0,01% | Acciones |
| GROUP ONE TRADING LLC | $673 | 1 871 | 0,01% | Acciones |
| JPMORGAN CHASE & CO | $287 | 931 | 0,00% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $284 | 790 | 0,00% | Acciones |
| SIMPLEX TRADING, LLC | $91 | 255 | 0,00% | Acciones |
| UBS Group AG | $37 | 102 | 0,00% | Acciones |
| SBI Securities Co., Ltd. | $36 | 100 | 0,00% | Acciones |
| Virtu Financial LLC | $16 | 45 467 | 0,00% | Acciones |
| GSA CAPITAL PARTNERS LLP | $10 | 27 146 | 0,00% | Acciones |
| Optiver Holding B.V. | $8 | 22 | 0,00% | Acciones |
Informantes de la empresa 20 insiders · 6 directivos · 10 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Daniel J Hicklin | President and Chief Executive Officer | 2 de enero de 2025 A | — | 0 | 0 | $0 |
| Timothy W. Trost | Chief Financial Officer | 2 de enero de 2025 A | — | 0 | 0 | $0 |
| Chulani Karunatilake | Chief Technology Officer | 2 de enero de 2025 A | — | 0 | 0 | $0 |
| Ellen Lubman | Chief Business Officer | 2 de enero de 2025 A | — | 0 | 0 | $0 |
| Randi Isaacs | Chief Medical Officer | 2 de enero de 2025 A | — | 0 | 0 | $0 |
| Cynthia Seidel-Dugan | Chief Scientific Officer | 2 de enero de 2024 A | 164 888 | 0 | 0 | $0 |
| Luke Evnin | Consejero | 7 de julio de 2026 S | 0 | 0 | 87 | $-3 255 563 |
| Michael B. Atkins | Consejero | 12 de junio de 2025 A | — | 0 | 0 | $0 |
| Anil K. Singhal | Consejero | 12 de junio de 2025 A | — | 0 | 0 | $0 |
| Meeta Chatterjee | Consejero | 12 de junio de 2025 A | — | 0 | 0 | $0 |
| Alon Lazarus | Consejero | 12 de junio de 2025 A | 2 046 634 | 0 | 0 | $0 |
| Briggs Morrison | Consejero | 12 de junio de 2025 A | — | 0 | 0 | $0 |
| Michael A. Sherman | Consejero | 12 de junio de 2025 A | — | 0 | 0 | $0 |
| Derek Dirocco | Consejero | 24 de mayo de 2024 A | — | 0 | 0 | $0 |
| Sakae Asanuma | Consejero | 4 de mayo de 2021 C | 2 068 909 | 0 | 0 | $0 |
| Taiho Ventures LLC | Propietario del 10% | 4 de mayo de 2021 C | 2 068 909 | 0 | 0 | $0 |
| UPMC | Propietario del 10% | 4 de mayo de 2021 C | 1 097 756 | 0 | 0 | $0 |
| HBM Healthcare Investments (Cayman) Ltd. | Propietario del 10% | 4 de mayo de 2021 C | 625 995 | 0 | 0 | $0 |
| Steven H. Bloom | — | 1 de mayo de 2025 A | — | 0 | 0 | $0 |
| Reid Leonard | — | 3 de enero de 2023 A | 14 102 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 4 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×13 presentaciones | 2 de julio de 2026 | 4,10% | Enmienda | — | SEC |
| MPM BioVentures 2014, L.P., MPM BioVentures 2014 (B), L.P., MPM Asset Management Investors BV2014 LLC, UBS Oncology Impact Fund L.P., MPM BioVentures 2014 GP LLC, MPM BioVentures 2014 LLC, Oncology Impact Fund (Cayman) Management L.P., MPM BioImpact LLC, ANSBERT GADICKE, LUKE EVNIN, Todd Foley, MPM ASSET MANAGEMENT LLC, MPM ONCOLOGY INNOVATIONS FUND LP, MPM Oncology Innovations Fund GP LLC ×8 presentaciones | 12 de mayo de 2026 | 3,80% | Enmienda | — | SEC |
| Taiho Ventures LLC | 13 de mayo de 2021 | — | Presentación inicial | Campaña de la junta directiva | SEC |
| Arkin Bio Ventures 2 L.P., Arkin Bio Venture GPGP Ltd., Moshe Arkin, Alon Lazarus | 10 de mayo de 2021 | — | Presentación inicial | Campaña de la junta directiva | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 2 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.