JBIO Jade Biosciences, Inc. - Common Stock
JBIO Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
JBIO Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Dividendos Rendimiento, ratio de pago, historial de dividendos, CAGR a 5 años
| Fecha ex-dividendo | Monto |
|---|---|
| 29 de abril de 2025 | $2,4000 |
JBIO Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 8 47,1%
- Compra 8 47,1%
- Mantener 1 5,9%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
8 analistas · 2026-08-14Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 31 de marzo de 2026 | $-0.57 | $-0.49 | -0.08% |
| 31 de diciembre de 2025 | $-0.59 | $-0.48 | -0.11% |
| 30 de septiembre de 2025 | $-0.48 | $-0.69 | 0.21% |
| 30 de junio de 2025 | $-0.86 | $-0.44 | -0.42% |
| 31 de marzo de 2025 | $-3.15 | $-8.57 | 5.4% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| JBIO | $761M | -4.8 | — | — | -47.7% | — |
| FBRX | $353M | -5.8 | 106.6% | -2555.2% | -86.9% | — |
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| BCAX | $953M | -6.7 | — | — | -33.0% | — |
| TYRA | $1.41B | -13.1 | — | — | -42.7% | — |
| XNCR | $1.10B | -12.3 | 13.7% | -73.2% | -14.0% | — |
| TRAX | — | — | — | — | — | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| ABSI | $529M | -4.2 | -38.2% | -4113.7% | -63.5% | — |
| AVBP | $854M | -4.7 | — | — | -59.7% | — |
| PURR | — | — | — | — | — | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $93M | $53M | $64M | $39M | $15M | $8M | |
| SG&A Expense | $20M | $21M | $17M | $15M | $8M | $949.0K | |
| Operating Expenses | $114M | $75M | $81M | $53M | $23M | $9M | |
| Operating Income | $-114M | $-75M | $-81M | $-53M | $-23M | $-9M | |
| Interest Expense | · | · | · | · | · | $75.0K | |
| Other Non-op | $-8.0K | $-19.0K | $-1.0K | $2M | $62.0K | $-722.0K | |
| Pretax Income | $-127M | $-70M | $-75M | $-51M | $-23M | $-10M | |
| Income Tax | $58.0K | $55.0K | $56.0K | $25.0K | $3.0K | · | |
| Net Income | $-127M | $-70M | $-76M | $-52M | $-23M | $-10M | |
| EPS (Basic) | $-3.19 | $-2.44 | $-2.87 | $-2.10 | $-1.87 | · | |
| EPS (Diluted) | $-3.19 | $-2.44 | $-2.87 | $-2.10 | $-1.87 | · | |
| Shares (Basic) | 31,359,958 | 28,582,194 | 26,331,630 | 24,472,104 | 12,293,629 | · | |
| Shares (Diluted) | 31,359,958 | 28,582,194 | 26,331,630 | 24,472,104 | 12,293,629 | · | |
| EBITDA | $-114M | $-75M | $-81M | $-53M | $-23M | · |
Balance general 21
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $88M | $69M | $23M | $22M | $54M | $5M | |
| Short-term Investments | $248M | $0 | $99M | $107M | $113M | · | |
| Prepaid Expense | $13M | $268.0K | $2M | $2M | $7M | $103.0K | |
| Current Assets | $349M | $70M | $124M | $131M | $174M | $5M | |
| PP&E (Net) | $170.0K | · | $288.0K | $242.0K | $186.0K | $39.0K | |
| PP&E (Gross) | · | · | · | · | · | $40.0K | |
| Accum. Depreciation | · | · | · | · | · | $1.0K | |
| Other Non-current Assets | $69.0K | $3M | $2M | $3M | $302.0K | · | |
| Total Assets | $350M | $73M | $127M | $135M | $175M | $5M | |
| Accounts Payable | $2M | $1M | $2M | $3M | $1M | $618.0K | |
| Accrued Liabilities | $9M | $4M | · | · | · | · | |
| Current Liabilities | $17M | $12M | $18M | $8M | $3M | $2M | |
| Capital Leases | $724.0K | $0 | $255.0K | $705.0K | $382.0K | · | |
| Total Liabilities | $17M | $120M | $18M | $9M | $3M | $2M | |
| Common Stock | $5.0K | $1.0K | $3.0K | $2.0K | $2.0K | · | |
| Paid-in Capital | $507M | $179.0K | $273M | $215M | $209M | $63.0K | |
| Retained Earnings | $-174M | $-47M | $-163M | $-88M | $-36M | $-13M | |
| AOCI | $129.0K | $0 | $237.0K | $-466.0K | $-59.0K | · | |
| Stockholders' Equity | $333M | $-47M | $109M | $127M | $172M | $-13M | |
| Liabilities + Equity | $350M | $73M | $127M | $135M | $175M | $5M | |
| Shares Outstanding | 49,316,287 | 3,672,794 | 27,762,703 | 24,722,974 | 24,410,393 | 243,076 |
Flujo de Efectivo 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $20M | $11M | $12M | $5M | $2M | $58.0K | |
| Deferred Tax | $-44.0K | · | · | · | · | · | |
| Operating Cash Flow | $-95M | $-71M | $-57M | $-39M | $-27M | $-8M | |
| CapEx | $196.0K | · | $142.0K | $195.0K | $181.0K | · | |
| Investing Cash Flow | $-247M | $56M | $12M | $7M | $-113M | · | |
| Stock Issued | · | $24M | $45M | · | $127M | · | |
| Net Stock Activity | · | $24M | $45M | · | $127M | · | |
| Financing Cash Flow | $361M | $25M | $46M | $396.0K | $190M | $9M | |
| Net Change in Cash | $19M | $10M | $1M | $-32M | $50M | $1M | |
| Free Cash Flow | $-95M | · | $-57M | $-39M | $-28M | · |
Rentabilidad 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -60.3% | -67.0% | -57.5% | -33.2% | -25.5% | · | |
| ROE | -47.7% | -233.8% | -64.2% | -38.8% | -13.0% | · | |
| ROIC | -34.2% | -97.7% | -74.4% | -42.0% | -13.4% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 21.1 | 20.9 | 7.0 | 16.9 | 68.4 | · | |
| Quick Ratio | 20.3 | 20.5 | 6.9 | 16.6 | 65.6 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-127M | $-70M | $-76M | $-52M | $-23M | · | |
| Market Cap | $761M | $2.69B | $21.99B | $25.35B | $10.07B | · | |
| P/E | -4.8 | -38.0 | -276.0 | -488.3 | -220.7 | · | |
| P/B | 2.3 | 35.2 | 200.9 | 200.0 | 58.4 | · | |
| P / Tangible Book | 2.3 | · | 200.9 | 200.0 | 58.4 | · | |
| P / Cash Flow | -8.0 | -37.8 | -387.3 | -648.1 | -367.6 | · | |
| P / FCF | -8.0 | · | -386.3 | -644.8 | -365.2 | · | |
| Earnings Yield | -20.7% | -2.6% | -0.36% | -0.20% | -0.45% | · |
Estado de resultados 13
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $50M | $36M | $29M | $22M | $23M | $20M | $-2M | $14M | $21M | $20M | $18M | $17M | $16M | $13M | $12M | $11M | |
| SG&A Expense | $9M | $7M | $6M | $5M | $5M | $3M | $11M | $1M | $5M | $5M | $4M | $4M | $4M | $4M | $4M | $3M | |
| Operating Expenses | $59M | $43M | $55M | $27M | $28M | $23M | $9M | $15M | $26M | $25M | $22M | $21M | $20M | $18M | $16M | $14M | |
| Operating Income | $-59M | $-43M | $-55M | $-27M | $-28M | $-23M | $-9M | $-15M | $-26M | $-25M | $-22M | $-21M | $-20M | $-18M | $-16M | $-14M | |
| Other Non-op | $-62.0K | $-9.0K | $4M | $-28.0K | $0 | $0 | $-1M | $0 | $1M | $-3.0K | $-2M | $1.0K | $1M | $1M | $2M | $4.0K | |
| Pretax Income | $-56M | $-40M | · | · | $-32M | $-38M | · | · | · | · | · | · | · | · | · | · | |
| Income Tax | $15.0K | $16.0K | $58.0K | $0 | $0 | · | · | $0 | · | · | · | · | · | · | · | · | |
| Net Income | $-56M | $-40M | $-32M | $-25M | $-32M | $-38M | $-5M | $-16M | $-25M | $-23M | $-20M | $-20M | $-19M | $-17M | $-15M | $-14M | |
| EPS (Basic) | $-0.76 | $-0.57 | $-1.76 | $-0.48 | $-0.86 | $-12.10 | $4.41 | $-5.16 | $-0.86 | $-0.83 | $-0.73 | $-0.71 | $-0.76 | $-0.67 | $-0.60 | $-0.56 | |
| EPS (Diluted) | $-0.76 | $-0.57 | $-1.76 | $-0.48 | $-0.86 | $-12.10 | $4.41 | $-5.16 | $-0.86 | $-0.83 | $-0.73 | $-0.71 | $-0.76 | $-0.67 | $-0.60 | $-0.56 | |
| Shares (Basic) | 61,050,775 | 57,777,165 | -65,640,708 | 39,584,489 | 28,431,158 | 3,155,500 | -31,125,176 | 3,155,500 | 28,756,043 | 27,795,827 | -51,253,264 | 27,640,542 | 25,166,505 | 24,777,847 | -48,803,578 | 24,454,786 | |
| Shares (Diluted) | 61,050,775 | 57,777,165 | -65,640,708 | 39,584,489 | 28,431,158 | 3,155,500 | -31,125,176 | 3,155,500 | 28,756,043 | 27,795,827 | -51,253,264 | 27,640,542 | 25,166,505 | 24,777,847 | -48,803,578 | 24,454,786 | |
| EBITDA | $-59M | $-43M | · | $-27M | $-28M | $-3M | · | $-17M | $-26M | $-25M | · | $-21M | $-20M | $-18M | · | $-14M |
Balance general 19
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $107M | $55M | $88M | $50M | $221M | $44M | $34M | $31M | $31M | $9M | $23M | $32M | $61M | $27M | $22M | $22M | |
| Short-term Investments | $354M | $256M | $248M | $149M | · | $32M | $45M | $58M | $73M | $90M | $99M | $103M | $89M | $92M | $107M | $120M | |
| Prepaid Expense | $10M | $7M | $13M | $2M | $2M | $1M | $1M | $2M | $7M | $4M | $2M | $2M | $2M | $2M | $2M | $3M | |
| Current Assets | $471M | $319M | $349M | $201M | $223M | $77M | $80M | $91M | $111M | $103M | $124M | $138M | $152M | $121M | $131M | $145M | |
| PP&E (Net) | $144.0K | $157.0K | $170.0K | $176.0K | $147.0K | $2.0K | $6.0K | $14.0K | $232.0K | $260.0K | $288.0K | $316.0K | $245.0K | $267.0K | $242.0K | $330.0K | |
| Other Non-current Assets | $69.0K | $69.0K | $69.0K | $174.0K | $60.0K | · | · | $81.0K | $81.0K | $3M | $2M | $2M | $2M | $3M | $3M | $1M | |
| Total Assets | $472M | $319M | $350M | $202M | $224M | $78M | $80M | $91M | $112M | $107M | $127M | $141M | $156M | $124M | $135M | $148M | |
| Accounts Payable | $7M | $4M | $2M | $1M | $8M | $69.0K | $224.0K | $908.0K | $4M | $3M | $2M | $4M | $6M | $5M | $3M | $5M | |
| Accrued Liabilities | $15M | $15M | $9M | $14M | $8M | · | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $32M | $22M | $17M | $22M | $22M | $2M | $4M | $10M | $17M | $16M | $18M | $15M | $13M | $11M | $8M | $8M | |
| Capital Leases | $628.0K | $679.0K | $724.0K | $747.0K | $792.0K | · | · | $81.0K | $206.0K | $329.0K | $255.0K | $358.0K | $476.0K | $591.0K | $705.0K | $800.0K | |
| Total Liabilities | $32M | $23M | $17M | $23M | $22M | $2M | $4M | $10M | $17M | $16M | $18M | $15M | $14M | $11M | $9M | $9M | |
| Common Stock | $6.0K | $5.0K | $5.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $2.0K | $2.0K | $2.0K | |
| Paid-in Capital | $711M | $512M | $507M | $322M | $319M | $311M | $309M | $308M | $306M | $278M | $273M | $269M | $266M | $218M | $215M | $213M | |
| Retained Earnings | $-271M | $-215M | $-174M | $-142M | $-117M | $-236M | $-233M | $-228M | $-211M | $-187M | $-163M | $-143M | $-123M | $-104M | $-88M | $-73M | |
| AOCI | $-660.0K | $-342.0K | $129.0K | $29.0K | $-24.0K | $50.0K | $105.0K | $224.0K | $-83.0K | $-33.0K | $237.0K | $-195.0K | $-223.0K | $-201.0K | $-466.0K | $-771.0K | |
| Stockholders' Equity | $440M | $296M | $333M | $179M | $202M | $75M | $76M | $80M | $94M | $91M | $109M | $126M | $142M | $113M | $127M | $139M | |
| Liabilities + Equity | $472M | $319M | $350M | $202M | $224M | $78M | $80M | $91M | $112M | $107M | $127M | $141M | $156M | $124M | $135M | $148M | |
| Shares Outstanding | 63,556,065 | 49,345,967 | 49,316,287 | 32,626,730 | 32,626,730 | 28,985,019 | 28,985,019 | 28,867,711 | 28,854,750 | 27,898,761 | 27,762,703 | 27,653,187 | 27,601,098 | 24,816,940 | 24,722,974 | 24,506,390 |
Flujo de Efectivo 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $14M | $7M | $11M | $4M | $4M | $2M | $3M | $27.0K | $4M | $4M | $3M | $3M | $3M | $2M | $2M | $1M | |
| Operating Cash Flow | $-44M | $-24M | $-34M | $-22M | $-37M | $-19M | $-11M | $-7M | $-20M | $-24M | $-15M | $-16M | $-15M | $-11M | $-15M | $-10M | |
| CapEx | · | · | $3.0K | $57.0K | · | · | · | · | · | · | $64.0K | $32.0K | $30.0K | $16.0K | $4.0K | $33.0K | |
| Investing Cash Flow | $-98M | $-8M | $-98M | $-149M | $-13M | $13M | $13M | $0 | $18M | $9M | $6M | $-13M | $4M | $15M | $14M | $5M | |
| Stock Issued | · | · | · | · | · | · | $307.0K | $0 | · | · | $0 | $0 | · | · | · | · | |
| Financing Cash Flow | $194M | $-795.0K | $170M | $0 | $191M | $-700.0K | $554.0K | $95M | $24M | $471.0K | $463.0K | $20.0K | $45M | $223.0K | $357.0K | $37.0K | |
| Net Change in Cash | $52M | $-33M | $38M | $-171M | $141M | $-19M | $3M | $88M | $22M | $-14M | $-9M | $-29M | $34M | $4M | $-22.0K | $-5M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | · | · | · | · | $-11M | · | · |
Rentabilidad 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -16.0% | -20.3% | · | -17.2% | -19.1% | -2.7% | · | -14.0% | -18.5% | -20.1% | · | -13.6% | -12.2% | -11.3% | · | -8.2% | |
| ROE | -17.4% | -21.7% | · | -19.4% | -21.7% | -3.0% | · | -15.8% | -21.0% | -22.7% | · | -14.8% | -13.0% | -12.0% | · | -8.5% | |
| ROIC | -13.4% | -14.7% | · | · | · | · | · | · | · | · | · | · | · | · | · | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.9 | 14.3 | · | 9.0 | 10.3 | 32.0 | · | 8.8 | 6.5 | 6.7 | · | 9.3 | 11.5 | 11.3 | · | 18.8 | |
| Quick Ratio | 14.6 | 14.0 | · | 8.9 | 10.2 | 31.5 | · | 8.6 | 6.1 | 6.4 | · | 9.2 | 11.3 | 11.2 | · | 18.5 |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-153M | $-136M | · | $-112M | $-111M | $-102M | · | $-84M | $-87M | $-78M | · | $-69M | $-61M | $-53M | · | $-43M | |
| Market Cap | $1.41B | $693M | · | $282M | $326M | $2.55B | · | $2.11B | $1.68B | $28.87B | · | $13.13B | $16.57B | $17.52B | · | $14.22B | |
| P/E | -8.3 | -1.0 | · | -1.3 | -1.4 | -12.7 | · | -9.7 | -18.4 | -348.5 | · | -175.9 | -242.0 | -325.3 | · | -329.7 | |
| P/B | 3.2 | 2.3 | · | 1.6 | 1.6 | 33.9 | · | 26.2 | 17.8 | 317.6 | · | 104.5 | 116.7 | 154.9 | · | 102.2 | |
| P / Tangible Book | 3.2 | 2.3 | · | 1.6 | 1.6 | 33.9 | · | 26.2 | 17.8 | 317.6 | · | 104.5 | 116.7 | 154.9 | · | 102.2 | |
| P / Cash Flow | · | -28.8 | · | · | · | -1069.4 | · | · | · | -1219.7 | · | · | · | -1533.6 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | · | · | · | · | -1531.4 | · | · | |
| Earnings Yield | -12.0% | -99.7% | · | -76.4% | -69.8% | -7.9% | · | -10.3% | -5.4% | -0.29% | · | -0.57% | -0.41% | -0.31% | · | -0.30% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-127M | $-70M | $-76M | $-52M | $-23M |
| EPS Diluido | $-3.19 | $-2.44 | $-2.87 | $-2.10 | $-1.87 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 21.1 | 20.9 | 7.0 | 16.9 | 68.4 |
| Ratio Rápido | 20.3 | 20.5 | 6.9 | 16.6 | 65.6 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-95M | — | $-57M | $-39M | $-28M |
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Propietarios institucionales (13F) 161 declarantes · $1.3B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 58 (+29 vs trimestre anterior) | 15 (+4 vs trimestre anterior) | 52 (+16 vs trimestre anterior) | 26 (-3 vs trimestre anterior) | +12.9M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| FMR LLC | $160 922 573 | 7 242 240 | 12,56% | Acciones |
| Fairmount Funds Management LLC | $101 178 637 | 4 553 494 | 7,90% | Acciones |
| RA CAPITAL MANAGEMENT, L.P. | $81 571 464 | 3 671 083 | 6,37% | Acciones |
| Venrock Adviser, LLC | $71 556 488 | 3 220 364 | 5,59% | Acciones |
| Bellevue Group AG | $67 948 671 | 3 057 996 | 5,31% | Acciones |
| Paradigm Biocapital Advisors LP | $63 491 539 | 2 857 405 | 4,96% | Acciones |
| STATE STREET CORP | $51 890 033 | 2 335 285 | 4,05% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $49 878 856 | 2 244 773 | 3,89% | Acciones |
| JANUS HENDERSON GROUP PLC | $43 557 008 | 3 105 669 | 3,40% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $42 458 243 | 1 910 812 | 3,31% | Acciones |
| Polar Capital Holdings Plc | $41 039 940 | 1 846 982 | 3,20% | Acciones |
| Avidity Partners Management LP | $37 789 732 | 1 700 708 | 2,95% | Acciones |
| Remedium Capital Partners, LLC | $35 057 605 | 1 577 750 | 2,74% | Acciones |
| Soleus Capital Management, L.P. | $34 456 332 | 1 550 690 | 2,69% | Acciones |
| BAKER BROS. ADVISORS LP | $27 340 066 | 1 230 426 | 2,13% | Acciones |
| Logos Global Management LP | $24 997 500 | 1 125 000 | 1,95% | Acciones |
| Versant Venture Management, LLC | $22 037 418 | 991 783 | 1,72% | Acciones |
| ACORN CAPITAL ADVISORS, LLC | $21 925 807 | 986 760 | 1,71% | Acciones |
| Foresite Capital Management VI LLC | $19 701 741 | 886 667 | 1,54% | Acciones |
| Balyasny Asset Management L.P. | $19 525 292 | 878 726 | 1,52% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $18 744 951 | 843 337 | 1,46% | Acciones |
| Affinity Asset Advisors, LLC | $18 672 577 | 840 350 | 1,46% | Acciones |
| SAMSARA BIOCAPITAL, LLC | $16 359 186 | 736 237 | 1,28% | Acciones |
| Pictet Asset Management Holding SA | $16 304 325 | 733 768 | 1,27% | Acciones |
| Aberdeen Group plc | $13 801 020 | 621 108 | 1,08% | Acciones |
| GOLDMAN SACHS GROUP INC | $13 387 928 | 602 517 | 1,05% | Acciones |
| MARSHALL WACE, LLP | $12 342 966 | 555 489 | 0,96% | Acciones |
| CITADEL ADVISORS LLC | $12 093 546 | 544 264 | 0,94% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $10 255 152 | 461 528 | 0,80% | Acciones |
| BANK OF AMERICA CORP /DE/ | $10 088 569 | 454 031 | 0,79% | Acciones |
| Blackstone Inc. | $9 672 810 | 435 320 | 0,76% | Acciones |
| Ikarian Capital, LLC | $9 495 694 | 427 349 | 0,74% | Acciones |
| Walleye Capital LLC | $8 116 344 | 365 272 | 0,63% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $6 989 257 | 314 548 | 0,55% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $6 774 145 | 304 867 | 0,53% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $4 825 229 | 217 157 | 0,38% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $4 431 312 | 199 429 | 0,35% | Acciones |
| Point72 Asset Management, L.P. | $3 715 273 | 167 204 | 0,29% | Acciones |
| Opaleye Management Inc. | $3 221 900 | 145 000 | 0,25% | Acciones |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $3 114 989 | 140 886 | 0,24% | Acciones |
| Quantinno Capital Management LP | $2 548 990 | 114 716 | 0,20% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $2 504 261 | 112 703 | 0,20% | Acciones |
| VANGUARD GROUP INC | $2 491 621 | 161 479 | 0,19% | Acciones |
| Sofinnova Investments, Inc. | $2 386 228 | 107 391 | 0,19% | Acciones |
| AMERIPRISE FINANCIAL INC | $2 378 718 | 107 053 | 0,19% | Acciones |
| Woodline Partners LP | $2 227 977 | 100 269 | 0,17% | Acciones |
| SEVEN GRAND MANAGERS, LLC | $2 222 000 | 100 000 | 0,17% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $2 221 489 | 99 977 | 0,17% | Acciones |
| Atle Fund Management AB | $1 967 714 | 88 556 | 0,15% | Acciones |
| Swiss National Bank | $1 850 926 | 83 300 | 0,14% | Acciones |
| RAYMOND JAMES FINANCIAL INC | $1 749 225 | 78 723 | 0,14% | Acciones |
| Longaeva Partners L.P. | $1 744 292 | 78 501 | 0,14% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $1 635 192 | 73 591 | 0,13% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $1 532 736 | 68 980 | 0,12% | Acciones |
| Trexquant Investment LP | $1 517 982 | 68 316 | 0,12% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 517 626 | 68 300 | 0,12% | Opción de venta |
| Harvest Investment Services, LLC | $1 399 482 | 62 983 | 0,11% | Acciones |
| Corient Private Wealth LP | $1 365 199 | 61 440 | 0,11% | Acciones |
| XTX Topco Ltd | $1 313 046 | 59 093 | 0,10% | Acciones |
| Verdad Advisers, LP | $1 252 852 | 56 384 | 0,10% | Acciones |
| Squarepoint Ops LLC | $1 210 012 | 54 456 | 0,09% | Acciones |
| CITIGROUP INC | $1 166 506 | 52 498 | 0,09% | Acciones |
| Maven Securities LTD | $1 111 000 | 50 000 | 0,09% | Acciones |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $1 074 870 | 48 374 | 0,08% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $1 007 921 | 45 361 | 0,08% | Acciones |
| Rafferty Asset Management, LLC | $947 216 | 42 629 | 0,07% | Acciones |
| RHUMBLINE ADVISERS | $908 965 | 40 908 | 0,07% | Acciones |
| Russell Investments Group, Ltd. | $869 734 | 39 141 | 0,07% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $812 963 | 36 587 | 0,06% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $797 698 | 35 900 | 0,06% | Opción de compra |
| Vanguard Global Advisers, LLC | $757 546 | 34 093 | 0,06% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $702 441 | 31 613 | 0,05% | Acciones |
| BlackRock, Inc. | $673 999 | 30 333 | 0,05% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $664 987 | 47 330 | 0,05% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $635 003 | 28 578 | 0,05% | Acciones |
| Voleon Capital Management LP | $617 205 | 27 777 | 0,05% | Acciones |
| Man Group plc | $580 453 | 26 123 | 0,05% | Acciones |
| D. E. Shaw & Co., Inc. | $526 614 | 23 700 | 0,04% | Acciones |
| Engineers Gate Manager LP | $502 594 | 22 619 | 0,04% | Acciones |
| Aquatic Capital Management LLC | $498 417 | 22 431 | 0,04% | Acciones |
| BARCLAYS PLC | $485 285 | 21 840 | 0,04% | Acciones |
| PROFUND ADVISORS LLC | $475 775 | 21 412 | 0,04% | Acciones |
| Virtus Investment Advisers, LLC | $473 930 | 21 329 | 0,04% | Acciones |
| Bank of New York Mellon Corp | $454 221 | 20 442 | 0,04% | Acciones |
| Ghisallo Capital Management LLC | $444 400 | 20 000 | 0,03% | Acciones |
| MetLife Investment Management, LLC | $438 601 | 19 739 | 0,03% | Acciones |
| KLP KAPITALFORVALTNING AS | $306 636 | 13 800 | 0,02% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $292 037 | 13 143 | 0,02% | Acciones |
| Invesco Ltd. | $284 327 | 12 796 | 0,02% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $256 019 | 11 522 | 0,02% | Acciones |
| State of New Jersey Common Pension Fund D | $221 445 | 9 966 | 0,02% | Acciones |
| Brevan Howard Capital Management LP | $215 623 | 9 704 | 0,02% | Acciones |
| DELTEC ASSET MANAGEMENT LLC | $209 668 | 9 436 | 0,02% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $204 824 | 9 218 | 0,02% | Acciones |
| UBS Group AG | $194 936 | 8 773 | 0,02% | Acciones |
| Vanguard Investments Australia, Ltd. | $173 916 | 7 827 | 0,01% | Acciones |
| Nuveen, LLC | $136 742 | 6 154 | 0,01% | Acciones |
| NORTHERN TRUST CORP | $113 633 | 5 114 | 0,01% | Acciones |
| MERCER GLOBAL ADVISORS INC /ADV | $109 545 | 4 930 | 0,01% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $109 489 | 4 952 | 0,01% | Acciones |
Informantes de la empresa 20 insiders · 4 directivos · 9 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Tom Frohlich | Chief Executive Officer | 12 de febrero de 2026 A | 86 331 | 0 | 0 | $0 |
| Bradford D. Dahms | Chief Financial Officer | 12 de febrero de 2026 A | 37 813 | 0 | 0 | $0 |
| Elizabeth Balta | Chief Legal Officer and Corporate Secretary | 12 de febrero de 2026 A | 28 125 | 0 | 0 | $0 |
| Andrew James King | Chief Scientific Officer & Head of Research and Development | 12 de febrero de 2026 A | 386 113 | 0 | 0 | $0 |
| Mark Eisner | Consejero | 25 de junio de 2026 A | — | 0 | 0 | $0 |
| Christopher W. Cain | Consejero | 9 de junio de 2026 A | — | 0 | 0 | $0 |
| Lawrence Otto Klein | Consejero | 9 de junio de 2026 A | — | 0 | 0 | $0 |
| Erin Lavelle | Consejero | 9 de junio de 2026 A | — | 0 | 0 | $0 |
| Eric Dobmeier | Consejero | 9 de junio de 2026 A | — | 0 | 0 | $0 |
| Allison Dorval | Consejero | 15 de julio de 2021 A | — | 0 | 0 | $0 |
| David S. Grayzel | Consejero | 2 de julio de 2021 C | 3 103 879 | 0 | 0 | $0 |
| Dr. Maha Katabi | Consejero | 2 de julio de 2021 C | 3 758 686 | 0 | 0 | $0 |
| Atlas Venture Fund XII, L.P. | Propietario del 10% | 15 de julio de 2022 J | 2 327 909 | 0 | 0 | $0 |
| Benjamin T Dake | — | 29 de junio de 2021 A | — | 0 | 0 | $0 |
| Hunter Gillies | — | 29 de junio de 2021 A | — | 0 | 0 | $0 |
| Joshua Resnick | — | 29 de junio de 2021 A | — | 0 | 0 | $0 |
| Mark T Iwicki | — | 29 de junio de 2021 A | — | 0 | 0 | $0 |
| George A Eldridge | — | 29 de junio de 2021 A | — | 0 | 0 | $0 |
| Timothy P Noyes | — | 29 de junio de 2021 A | — | 0 | 0 | $0 |
| Ralph Niven | — | 29 de junio de 2021 A | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 5 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Fairmount Funds Management LLC, Fairmount Healthcare Fund II L.P., Fairmount Healthcare Co-Invest IV L.P., Peter Evan Harwin, Tomas Kiselak ×3 presentaciones | 9 de junio de 2026 | 19,99% | Enmienda | — | SEC |
| Sofinnova Venture Partners X, L.P. ("SVP X"), Sofinnova Management X, L.P. ("SM X LP"), Sofinnova Management X-A, L.L.C. ("SM X LLC"), Dr. James I. Healy ("Healy"), Dr. Maha Katabi ("Katabi") | 5 de marzo de 2026 | 0,30% | Enmienda | Inversión pasiva | SEC |
| Atlas Venture Fund XII, L.P., Atlas Venture Associates XII, L.P., Atlas Venture Associates XII, LLC ×5 presentaciones | 30 de abril de 2025 | 0,20% | Enmienda | — | SEC |
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×5 presentaciones | 30 de abril de 2025 | 4,10% | Enmienda | — | SEC |
| Sofinnova Venture Partners X, L.P. (“SVP X”), Sofinnova Management X, L.P. (“SM X LP”), Sofinnova Management X-A, L.L.C. (“SM X LLC”), Dr. James I. Healy (“Healy”), Dr. Maha Katabi (“Katabi”) ×3 presentaciones | 20 de febrero de 2024 | — | Presentación inicial | Inversión pasiva | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 24 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| BBC · ETFis Series Trust I | 1,20% | 18 425 NS | 30 de abril de 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,17% | 90 180 NS | 30 de abril de 2026 | N-PORT |
| IWC · iShares Trust | 0,16% | 110 226 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,12% | 111 509 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,04% | 291 651 SH | 8 de agosto de 2026 | Diario |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,04% | 53 058 NS | 31 de mayo de 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,04% | 34 886 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,02% | 834 822 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 187 416 SH | 8 de agosto de 2026 | Diario |
| ISCB · iShares Trust | 0,02% | 2 353 SH | 8 de agosto de 2026 | Diario |
| ITWO · ProShares Trust | 0,02% | 1 500 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 489 225 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 124 984 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,01% | 1 173 NS | 31 de mayo de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 3 435 NS | 31 de mayo de 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 2 542 SH | 8 de agosto de 2026 | Diario |
| URTY · ProShares Trust | 0,01% | 1 189 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 25 716 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 30 NS | 31 de mayo de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 71 137 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 14 895 SH | 8 de agosto de 2026 | Diario |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 5 087 NS | 31 de mayo de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 699 343 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 2 733 SH | 8 de agosto de 2026 | Diario |