RIGL Rigel Pharmaceuticals, Inc. - Common Stock
RIGL Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
RIGL Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
RIGL Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 4 36,4%
- Compra 4 36,4%
- Mantener 3 27,3%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
5 analistas · 2026-08-17Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $0.88 | $0.63 | 0.25% |
| 31 de marzo de 2026 | $0.44 | $0.78 | -0.34% |
| 31 de diciembre de 2025 | $1.15 | $1.27 | -0.12% |
| 30 de septiembre de 2025 | $1.46 | $0.87 | 0.59% |
| 30 de junio de 2025 | $3.28 | $2.63 | 0.65% |
| 31 de marzo de 2025 | $0.63 | $0.09 | 0.54% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| RIGL | $784M | 2.2 | 64.1% | 124.7% | 155.1% | — |
| FTH | — | — | — | — | — | — |
| IMMX | $277M | -5.9 | — | — | -59.8% | — |
| AURA | $347M | -3.1 | -29.7% | -1601.4% | -68.2% | — |
| MNPR | — | — | — | — | — | — |
| ACHV | — | -4.0 | — | — | — | — |
| CTMX | $725M | — | -44.8% | -22.8% | -15.9% | — |
| RGNX | $733M | -3.8 | 104.5% | -113.8% | -122.5% | — |
| NGNE | $319M | -4.9 | — | — | -33.6% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $294M | $179M | $117M | $120M | $149M | $109M | $59M | $45M | $4M | $20M | |
| Cost of Revenue | $20M | $19M | $7M | $2M | $1M | $895.0K | $906.0K | $287.0K | · | · | |
| R&D Expense | $33M | $23M | $25M | · | · | · | · | · | · | · | |
| SG&A Expense | $116M | $113M | $106M | $112M | $92M | $77M | $75M | $70M | $38M | $21M | |
| Operating Expenses | $169M | $155M | $137M | $176M | $162M | $138M | $128M | $117M | $84M | $90M | |
| Operating Income | $125M | $24M | $-20M | $-56M | $-12M | $-29M | $-69M | $-73M | $-80M | $-70M | |
| Interest Expense | · | $8M | $7M | $4M | $5M | $1M | $335.0K | · | · | · | |
| Interest Income | $4M | $2M | $2M | $684.0K | $47.0K | $582.0K | $3M | $2M | $892.0K | $437.0K | |
| Pretax Income | $122M | $18M | $-25M | $-59M | $-17M | $-30M | $-67M | · | · | · | |
| Income Tax | $-245M | $881.0K | $0 | · | $605.0K | · | · | $0 | $0 | $0 | |
| Net Income | $367M | $17M | $-25M | $-59M | $-18M | $-30M | $-67M | $-70M | $-78M | $-69M | |
| EPS (Basic) | $20.40 | $0.99 | $-1.44 | $-3.44 | $-0.11 | $-0.18 | $-0.40 | · | · | · | |
| EPS (Diluted) | $19.48 | $0.99 | $-1.44 | $-3.44 | $-0.11 | $-0.18 | $-0.40 | · | · | · | |
| Shares (Basic) | 17,987,000 | 17,579,000 | 17,401,000 | 17,049,000 | 170,492,000 | 168,754,000 | 167,400,000 | · | · | · | |
| Shares (Diluted) | 18,840,000 | 17,687,000 | 17,401,000 | 17,049,000 | 170,492,000 | 168,754,000 | 167,400,000 | · | · | · | |
| EBITDA | $128M | $26M | $-19M | $-55M | $-11M | $-28M | $-68M | $-72M | · | $-69M |
Balance general 26
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $41M | $57M | $33M | $24M | $19M | $30M | $23M | $76M | $38M | $18M | |
| Short-term Investments | $114M | $21M | $24M | $34M | $106M | $27M | $76M | $52M | $77M | $57M | |
| Receivables | $52M | $42M | $31M | $40M | $15M | $16M | $10M | $4M | $0 | $0 | |
| Inventory | $12M | $6M | $6M | $9M | $7M | $2M | $1M | $894.0K | · | · | |
| Prepaid Expense | $22M | $10M | $6M | $8M | $7M | $14M | $9M | $3M | $2M | $1M | |
| Other Current Assets | $5M | $5M | · | · | · | · | · | · | · | · | |
| Current Assets | $240M | $135M | $99M | $116M | $154M | $89M | $119M | $137M | $117M | $76M | |
| PP&E (Net) | $30.0K | $92.0K | $165.0K | $857.0K | $2M | $3M | $2M | $1M | $875.0K | $1M | |
| PP&E (Gross) | $347.0K | $353.0K | $2M | $12M | $17M | $16M | $15M | $14M | $13M | $20M | |
| Accum. Depreciation | $317.0K | $261.0K | $2M | $11M | $15M | $14M | $13M | $13M | $12M | $19M | |
| Intangibles | $25M | $27M | $14M | $15M | · | · | · | · | · | · | |
| Other Non-current Assets | $2M | $2M | $3M | $640.0K | $974.0K | $824.0K | $696.0K | $735.0K | $803.0K | $764.0K | |
| Total Assets | $514M | $164M | $117M | $134M | $167M | $110M | $148M | $139M | $119M | $78M | |
| Accounts Payable | $7M | $3M | $7M | $23M | $4M | $4M | $4M | $6M | $3M | $6M | |
| Accrued Liabilities | · | · | · | · | $4M | $4M | $3M | · | · | · | |
| Current Liabilities | $99M | $63M | $53M | $65M | $64M | $41M | $58M | $28M | $18M | $23M | |
| Capital Leases | $395.0K | $0 | $285.0K | $972.0K | $759.0K | $11M | $19M | · | · | · | |
| Other Non-current Liabilities | $0 | $40M | $40M | $42M | $53M | $5M | $5M | · | $38.0K | $2.0K | |
| Total Liabilities | $122M | $161M | $146M | $148M | $137M | · | · | · | · | · | |
| Long-term Debt | $52M | $60M | $60M | $40M | $20M | $20M | $10M | · | · | · | |
| Common Stock | $18.0K | $18.0K | $17.0K | $174.0K | $172.0K | $169.0K | $168.0K | $167.0K | $147.0K | $100.0K | |
| Retained Earnings | $-1.02B | $-1.39B | $-1.41B | $-1.38B | $-1.32B | $-1.31B | $-1.28B | $-1.21B | $-1.14B | $-1.06B | |
| AOCI | $181.0K | $10.0K | $8.0K | $-153.0K | $-102.0K | $-4.0K | $23.0K | $-24.0K | $-82.0K | $-18.0K | |
| Stockholders' Equity | $391M | $3M | $-29M | $-14M | $30M | $34M | $54M | $110M | $101M | $55M | |
| Liabilities + Equity | $514M | $164M | $117M | $134M | $167M | $110M | $148M | $139M | $119M | $78M | |
| Shares Outstanding | 18,310,934 | 17,710,216 | 17,482,513 | 173,398,645 | 171,602,226 | 169,316,782 | 167,987,850 | 167,171,505 | 146,814,906 | 99,269,418 |
Flujo de Efectivo 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $2M | $2M | $1M | $998.0K | $1M | $706.0K | $683.0K | $594.0K | $465.0K | $941.0K | |
| Stock-based Comp | $13M | $12M | $9M | $12M | $9M | $7M | $9M | $8M | $6M | $7M | |
| Deferred Tax | $-246M | $0 | $0 | · | · | · | · | · | · | · | |
| Amort. of Intangibles | $2M | $2M | $1M | $100.0K | · | · | · | · | · | · | |
| Restructuring | · | · | · | $1M | $4M | · | · | · | · | $6M | |
| Other Non-cash | $-61M | $-635.0K | $9M | $-29M | $13M | $-30M | $16M | $3M | · | · | |
| Operating Cash Flow | $76M | $31M | $-6M | $-74M | $6M | $-52M | $-42M | $-59M | $-78M | $-76M | |
| CapEx | · | · | · | $450.0K | $627.0K | $1M | $1M | $1M | $164.0K | $804.0K | |
| Investing Cash Flow | $-92M | $4M | $-4M | $73M | $-80M | $47M | $-24M | $25M | $-19M | $25M | |
| Stock Issued | · | · | · | · | · | · | · | $67M | $114M | $24M | |
| Net Stock Activity | · | · | · | · | · | · | · | $67M | · | $30M | |
| Financing Cash Flow | $601.0K | $-12M | $18M | $7M | $63M | $13M | $11M | $72M | $118M | $25M | |
| Net Change in Cash | · | · | · | · | · | · | · | $38M | $21M | $-26M | |
| Taxes Paid | $1M | $331.0K | $81.0K | · | · | · | · | · | · | · | |
| Free Cash Flow | · | · | · | $-74M | $5M | $-53M | $-43M | $-60M | · | $-77M | |
| Levered FCF | · | · | · | · | $221.1K | · | · | · | · | · |
Rentabilidad 7
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | 42.6% | 13.5% | -17.5% | -46.2% | -8.4% | -26.7% | -116.5% | -163.3% | · | · | |
| Net Margin | 124.7% | 9.8% | -21.5% | -48.7% | -12.0% | -27.4% | -112.8% | -158.3% | · | · | |
| Pretax Margin | 41.4% | 10.2% | -21.5% | -48.7% | -11.6% | · | · | · | · | · | |
| EBITDA Margin | 43.5% | 14.7% | -16.5% | -45.4% | -7.6% | -26.0% | -115.4% | -162.0% | · | · | |
| ROA | 108.3% | 12.4% | -20.0% | -38.8% | -12.9% | -23.1% | -46.7% | -54.6% | · | · | |
| ROE | 155.1% | -308.2% | 83.0% | 350.2% | -44.8% | -70.0% | -109.0% | -66.1% | · | · | |
| ROIC | 96.5% | 700.5% | · | · | -42.6% | · | · | · | · | · |
Liquidez y Solvencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.4 | 2.1 | 1.9 | 1.8 | 2.4 | 2.2 | 2.0 | 4.9 | · | 3.4 | |
| Quick Ratio | 2.1 | 1.9 | 1.6 | 1.5 | 2.2 | 1.8 | 1.9 | 4.8 | · | 3.3 | |
| Interest Coverage | · | 3.1 | -3.0 | -15.0 | -2.6 | -21.4 | -206.2 | · | · | · |
Eficiencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.9 | 1.3 | 0.9 | 0.8 | 1.1 | 0.8 | 0.4 | 0.3 | · | · | |
| Inventory Turnover | 2.2 | 3.2 | 1.0 | 0.2 | 0.3 | 0.6 | 0.8 | 0.6 | · | · | |
| Receivables Turnover | 6.3 | 5.0 | 3.3 | 4.3 | 9.5 | 8.3 | 8.4 | 21.8 | · | · |
Tasas de Crecimiento 5
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 64.1% | 53.4% | -2.8% | -19.4% | 37.4% | · | · | · | · | · | |
| Revenue CAGR 3Y | 34.8% | 6.3% | 2.5% | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 22.1% | · | · | · | · | · | · | · | · | · | |
| EPS YoY | 1867.7% | · | · | · | · | · | · | · | · | · | |
| Net Income YoY | 1999.1% | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $294M | $179M | $117M | $120M | $149M | $109M | $59M | $45M | $4M | $20M | |
| Net Income TTM | $367M | $17M | $-25M | $-59M | $-18M | $-30M | $-67M | $-70M | $-78M | $-69M | |
| Market Cap | $784M | $298M | $2.53B | $2.60B | $4.55B | $5.93B | $3.59B | $3.84B | · | $2.36B | |
| P/E | 2.2 | 17.0 | -10.1 | -4.4 | -240.9 | -194.4 | -53.5 | · | · | · | |
| P/S | 2.7 | 1.7 | 21.7 | 21.6 | 30.5 | 54.6 | 60.6 | 86.4 | · | 115.9 | |
| P/B | 2.0 | 90.6 | -88.5 | -191.0 | 149.7 | 174.2 | 66.8 | 35.0 | · | 42.9 | |
| P / Tangible Book | 2.1 | · | · | · | 149.7 | 174.2 | · | · | · | · | |
| P / Cash Flow | 10.4 | 9.5 | -441.4 | -35.3 | 773.6 | -113.6 | -86.6 | -65.4 | · | -31.1 | |
| P / FCF | · | · | · | -35.0 | 866.0 | -110.9 | -83.7 | -64.2 | · | -30.8 | |
| Earnings Yield | 45.5% | 5.9% | -9.9% | -22.9% | -0.42% | -0.51% | -1.9% | · | · | · |
Estado de resultados 16
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $79M | $59M | $70M | $69M | $102M | $53M | $58M | $55M | $37M | $30M | $36M | $28M | $27M | $26M | $51M | $22M | |
| Cost of Revenue | $9M | $5M | $6M | $5M | $5M | $4M | $6M | $8M | $3M | $2M | $4M | $1M | $1M | $977.0K | $342.0K | $250.0K | |
| R&D Expense | $14M | $12M | · | · | $7M | $8M | · | · | · | · | · | · | · | · | · | · | |
| SG&A Expense | $33M | $31M | $30M | $29M | $29M | $28M | $30M | $27M | $28M | $28M | $27M | $25M | $26M | $28M | $32M | $26M | |
| Operating Expenses | $55M | $47M | $47M | $41M | $41M | $41M | $41M | $41M | $36M | $36M | $34M | $33M | $32M | $39M | $49M | $41M | |
| Operating Income | $24M | $12M | $23M | $28M | $61M | $13M | $17M | $14M | $447.0K | $-7M | $2M | $-4M | $-5M | $-13M | $2M | $-18M | |
| Interest Expense | · | · | · | $2M | $2M | $2M | · | $2M | $2M | $2M | · | $2M | $2M | $1M | $1M | $826.0K | |
| Interest Income | $789.0K | $1M | $1M | $1M | $753.0K | $591.0K | $522.0K | $425.0K | $552.0K | $593.0K | $678.0K | $672.0K | $529.0K | $393.0K | $429.0K | $192.0K | |
| Pretax Income | $24M | $12M | $23M | $28M | $60M | $12M | $15M | $12M | $-1M | $-8M | · | · | · | · | $1M | $-19M | |
| Income Tax | $6M | $3M | $-245M | $-280.0K | $369.0K | $65.0K | $881.0K | $0 | $0 | $0 | · | · | · | · | · | $0 | |
| Net Income | $17M | $9M | $268M | $28M | $60M | $11M | $14M | $12M | $-1M | $-8M | $737.0K | $-6M | $-7M | $-14M | $1M | $-19M | |
| EPS (Basic) | $0.93 | $0.47 | $14.88 | $1.55 | $3.33 | $0.64 | $0.81 | $0.71 | $-0.06 | $-0.47 | $-0.65 | $-0.33 | $-0.38 | $-0.08 | $-3.09 | $-0.11 | |
| EPS (Diluted) | $0.88 | $0.44 | $14.11 | $1.46 | $3.28 | $0.63 | $0.82 | $0.70 | $-0.06 | $-0.47 | $-0.65 | $-0.33 | $-0.38 | $-0.08 | $-3.09 | $-0.11 | |
| Shares (Basic) | 18,541,000 | 18,412,000 | -35,744,000 | 18,038,000 | 17,885,000 | 17,808,000 | -35,090,000 | 17,600,000 | 17,549,000 | 17,520,000 | -190,959,000 | 17,436,000 | 17,356,000 | 173,568,000 | -499,708,000 | 172,836,000 | |
| Shares (Diluted) | 19,570,000 | 19,686,000 | -36,647,000 | 19,156,000 | 18,162,000 | 18,169,000 | -35,030,000 | 17,648,000 | 17,549,000 | 17,520,000 | -190,959,000 | 17,436,000 | 17,356,000 | 173,568,000 | -499,708,000 | 172,836,000 | |
| EBITDA | $24M | $12M | · | $28M | $61M | $13M | · | $14M | $447.0K | $-7M | · | $-4M | $-5M | $-12M | · | $-18M |
Balance general 25
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $61M | $24M | $41M | $49M | $53M | $46M | $57M | $52M | $36M | $26M | · | $45M | $49M | $40M | · | $30M | |
| Short-term Investments | $35M | $122M | $114M | $89M | $55M | $31M | $21M | $9M | $13M | $24M | · | $17M | $16M | $18M | · | $52M | |
| Receivables | $56M | $50M | $52M | $46M | $40M | $42M | $42M | $31M | $29M | $28M | · | $24M | $21M | $29M | · | $16M | |
| Inventory | $14M | $12M | $12M | $13M | $10M | $5M | $6M | $5M | $8M | $7M | · | $6M | $11M | $11M | · | $7M | |
| Prepaid Expense | $20M | $26M | $22M | $19M | $17M | $23M | $10M | $10M | $9M | $9M | · | $3M | $5M | $8M | · | $6M | |
| Other Current Assets | $5M | $7M | $5M | $6M | $5M | $6M | $5M | · | · | · | · | · | · | · | · | · | |
| Current Assets | $186M | $234M | $240M | $215M | $175M | $147M | $135M | $106M | $95M | $92M | · | $95M | $101M | $107M | · | $110M | |
| PP&E (Net) | · | · | $30.0K | $54.0K | $57.0K | $76.0K | $92.0K | $99.0K | $115.0K | $140.0K | · | $190.0K | $215.0K | $294.0K | · | $2M | |
| PP&E (Gross) | · | · | $347.0K | · | · | · | $353.0K | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $317.0K | · | · | · | $261.0K | · | · | · | · | · | · | · | · | · | |
| Intangibles | $94M | $24M | $25M | $25M | $26M | $27M | $27M | $28M | $28M | $29M | · | · | · | · | · | · | |
| Other Non-current Assets | $3M | $2M | $2M | $1M | $4M | $2M | $2M | $5M | $5M | $4M | · | $5M | $541.0K | $542.0K | · | $484.0K | |
| Total Assets | $521M | $505M | $514M | $243M | $207M | $176M | $164M | $139M | $128M | $127M | · | $115M | $117M | $124M | · | $116M | |
| Accounts Payable | $4M | $4M | $7M | $4M | $7M | $4M | $3M | $4M | $6M | $9M | · | $8M | $5M | $6M | · | $3M | |
| Current Liabilities | $96M | $89M | $99M | $94M | $87M | $67M | $63M | $54M | $59M | $73M | · | $48M | $44M | $46M | · | $47M | |
| Capital Leases | $58.0K | $228.0K | $395.0K | $556.0K | $714.0K | $864.0K | $0 | · | · | $100.0K | · | $466.0K | $628.0K | $802.0K | · | · | |
| Other Non-current Liabilities | · | · | $0 | · | · | $40M | $40M | $40M | $40M | $40M | · | $39M | $41M | $42M | · | $49M | |
| Total Liabilities | $96M | $105M | $122M | $125M | $125M | $157M | $161M | $154M | $158M | $158M | · | $147M | $145M | $148M | · | · | |
| Long-term Debt | · | $45M | $52M | $60M | $60M | $60M | · | $60M | $60M | $60M | · | $60M | $60M | $60M | · | $40M | |
| Common Stock | $18.0K | $18.0K | $18.0K | $18.0K | $18.0K | $18.0K | $18.0K | $17.0K | $17.0K | $175.0K | · | $175.0K | $175.0K | $174.0K | · | $173.0K | |
| Retained Earnings | $-997M | $-1.01B | $-1.02B | $-1.29B | $-1.32B | $-1.38B | $-1.39B | $-1.40B | $-1.42B | $-1.42B | · | $-1.41B | $-1.40B | $-1.40B | · | $-1.38B | |
| AOCI | $-148.0K | $-128.0K | $181.0K | $96.0K | $6.0K | $-2.0K | $10.0K | $11.0K | $-9.0K | $-5.0K | · | $-15.0K | $-25.0K | $-27.0K | · | $-286.0K | |
| Stockholders' Equity | $425M | $400M | $391M | $118M | $82M | $19M | $3M | $-15M | $-30M | $-32M | $-29M | $-32M | $-28M | $-24M | $-14M | $-20M | |
| Liabilities + Equity | $521M | $505M | $514M | $243M | $207M | $176M | $164M | $139M | $128M | $127M | · | $115M | $117M | $124M | · | $116M | |
| Shares Outstanding | · | · | 18,310,934 | · | · | · | 17,710,216 | · | · | · | · | · | · | · | · | · |
Flujo de Efectivo 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $848.0K | $597.0K | $601.0K | $603.0K | $607.0K | $604.0K | $604.0K | $611.0K | $613.0K | $400.0K | $293.0K | $292.0K | $296.0K | $357.0K | $284.0K | $240.0K | |
| Stock-based Comp | $7M | $3M | $3M | $3M | $3M | $3M | $2M | $3M | $3M | $5M | $2M | $2M | $2M | $3M | $4M | $3M | |
| Amort. of Intangibles | · | $600.0K | $600.0K | $600.0K | $600.0K | $600.0K | $500.0K | $600.0K | $600.0K | $400.0K | $200.0K | $300.0K | $300.0K | $300.0K | · | · | |
| Other Non-cash | · | $-10M | · | · | · | $-16M | · | · | · | $-2M | · | · | · | $6M | · | · | |
| Operating Cash Flow | $31M | $3M | $22M | $24M | $31M | $-893.0K | $15M | $22M | $302.0K | $-5M | $-6M | $-1M | $6M | $-4M | $-22M | $-13M | |
| CapEx | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $189.0K | |
| Investing Cash Flow | $17M | $-8M | $-25M | $-33M | $-23M | $-11M | $-11M | $4M | $11M | $313.0K | $-7M | $-1M | $3M | $777.0K | $19M | $10M | |
| Stock Repurchased | $511.0K | $4M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Stock Activity | · | $-4M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $-12M | $-11M | $-5M | $4M | $418.0K | $484.0K | $1M | $-10M | $-752.0K | $-3M | $486.0K | $-869.0K | $-373.0K | $19M | $-2M | $6M |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | 29.9% | 20.2% | · | 40.9% | 60.1% | 23.9% | · | 25.4% | 1.2% | -23.6% | · | -15.9% | -19.6% | -48.8% | · | -82.1% | |
| Net Margin | 22.0% | 14.7% | · | 40.2% | 58.6% | 21.5% | · | 22.5% | -2.8% | -27.9% | · | -20.2% | -24.6% | -51.9% | · | -85.0% | |
| Pretax Margin | 30.0% | 19.8% | · | 39.8% | 59.0% | 21.6% | · | · | · | · | · | · | · | · | · | -85.0% | |
| EBITDA Margin | 29.9% | 21.2% | · | 40.9% | 60.1% | 25.1% | · | 25.4% | 1.2% | -22.2% | · | -15.9% | -19.6% | -47.4% | · | -82.1% | |
| ROA | 4.8% | 2.5% | · | 14.6% | 35.6% | 7.6% | · | 9.8% | -0.84% | -6.6% | · | -4.9% | -5.4% | -9.9% | · | -12.6% | |
| ROE | 6.8% | 4.1% | · | 54.2% | 229.2% | -174.7% | · | -53.5% | 3.5% | 29.5% | · | 22.0% | 41.5% | 155.1% | · | -127.6% | |
| ROIC | 4.1% | 2.2% | · | 24.4% | 74.1% | 68.4% | · | · | · | · | · | · | · | · | · | 92.8% |
Liquidez y Solvencia 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.9 | 2.6 | · | 2.3 | 2.0 | 2.2 | · | 2.0 | 1.6 | 1.3 | · | 2.0 | 2.3 | 2.4 | · | 2.3 | |
| Quick Ratio | 1.6 | 2.2 | · | 1.9 | 1.7 | 1.8 | · | 1.7 | 1.3 | 1.1 | · | 1.8 | 1.9 | 1.9 | · | 2.1 | |
| Interest Coverage | · | · | · | 15.0 | 32.6 | 6.9 | · | 6.8 | 0.2 | -3.7 | · | -2.4 | -2.8 | -10.6 | · | -22.3 |
Eficiencia 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.2 | 0.2 | · | 0.4 | 0.6 | 0.4 | · | 0.4 | 0.3 | 0.2 | · | 0.2 | 0.2 | 0.2 | · | 0.1 | |
| Inventory Turnover | 0.7 | 0.6 | · | 0.5 | 0.5 | 0.8 | · | 1.5 | 0.3 | 0.2 | · | 0.2 | 0.1 | 0.1 | · | 0.0 | |
| Receivables Turnover | 1.6 | 1.3 | · | 1.8 | 3.0 | 1.5 | · | 2.0 | 1.5 | 1.0 | · | 1.4 | 1.4 | 1.2 | · | 1.5 |
Valoración (TTM) 4
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $309M | $283M | · | $280M | $247M | $175M | · | $150M | $121M | $111M | · | $104M | $105M | $95M | · | $91M | |
| Net Income TTM | $113M | $108M | · | $111M | $82M | $15M | · | $-3M | $-22M | $-34M | · | $-45M | $-53M | $-74M | · | $-81M | |
| P/E | 6.5 | 4.7 | · | 4.7 | 4.1 | 22.5 | · | -101.1 | -6.6 | -11.7 | · | -12.0 | -19.8 | -30.7 | · | -25.1 | |
| Earnings Yield | 15.5% | 21.5% | · | 21.4% | 24.3% | 4.5% | · | -0.99% | -15.1% | -8.5% | · | -8.3% | -5.0% | -3.3% | · | -4.0% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $294M | $179M | $117M | $120M | $149M |
| Margen Operativo % | 42.6% | 13.5% | -17.5% | -46.2% | -8.4% |
| Beneficio neto | $367M | $17M | $-25M | $-59M | $-18M |
| EPS Diluido | $19.48 | $0.99 | $-1.44 | $-3.44 | $-0.11 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 2.4 | 2.1 | 1.9 | 1.8 | 2.4 |
| Ratio Rápido | 2.1 | 1.9 | 1.6 | 1.5 | 2.2 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | — | — | — | $-74M | $5M |
Últimas noticias Noticias recientes que mencionan a esta empresa
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Propietarios institucionales (13F) 170 declarantes · $451.1M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 37 (+25 vs trimestre anterior) | 22 (-22 vs trimestre anterior) | 43 (-25 vs trimestre anterior) | 59 (+12 vs trimestre anterior) | +1.6M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Soleus Capital Management, L.P. | $72 117 876 | 1 843 504 | 15,99% | Acciones |
| ARMISTICE CAPITAL, LLC | $65 408 640 | 1 672 000 | 14,50% | Acciones |
| STATE STREET CORP | $40 684 565 | 1 039 994 | 9,02% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $30 713 386 | 785 107 | 6,81% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $29 016 008 | 741 718 | 6,43% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $16 233 871 | 414 860 | 3,60% | Acciones |
| CM Management, LLC | $9 780 000 | 250 000 | 2,17% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $9 143 439 | 233 728 | 2,03% | Acciones |
| D. E. Shaw & Co., Inc. | $8 343 357 | 213 276 | 1,85% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $8 288 120 | 211 864 | 1,84% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $8 120 451 | 207 578 | 1,80% | Acciones |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $7 628 000 | 195 000 | 1,69% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $6 049 008 | 154 627 | 1,34% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $5 705 496 | 145 846 | 1,26% | Acciones |
| GOLDMAN SACHS GROUP INC | $5 507 079 | 140 774 | 1,22% | Acciones |
| VANGUARD GROUP INC | $5 228 301 | 122 071 | 1,16% | Acciones |
| O'SHAUGHNESSY ASSET MANAGEMENT, LLC | $5 131 644 | 131 177 | 1,14% | Acciones |
| AQR CAPITAL MANAGEMENT LLC | $4 875 134 | 124 620 | 1,08% | Acciones |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $4 858 078 | 124 184 | 1,08% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $4 762 195 | 121 733 | 1,06% | Acciones |
| BANK OF AMERICA CORP /DE/ | $4 448 962 | 113 726 | 0,99% | Acciones |
| GLOBEFLEX CAPITAL L P | $4 407 729 | 112 672 | 0,98% | Acciones |
| CenterBook Partners LP | $4 286 574 | 109 575 | 0,95% | Acciones |
| FMR LLC | $3 759 432 | 96 100 | 0,83% | Acciones |
| RITHOLTZ WEALTH MANAGEMENT | $3 694 884 | 94 450 | 0,82% | Acciones |
| JANUS HENDERSON GROUP PLC | $3 674 114 | 135 877 | 0,81% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $3 665 114 | 93 689 | 0,81% | Acciones |
| FIRST TRUST ADVISORS LP | $3 182 099 | 81 342 | 0,71% | Acciones |
| Empowered Funds, LLC | $3 097 678 | 79 184 | 0,69% | Acciones |
| Brandywine Global Investment Management, LLC | $3 065 343 | 71 570 | 0,68% | Acciones |
| FRANKLIN RESOURCES INC | $2 831 114 | 72 370 | 0,63% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2 687 544 | 68 700 | 0,60% | Opción de compra |
| Squarepoint Ops LLC | $2 607 661 | 66 658 | 0,58% | Acciones |
| BlackRock, Inc. | $2 389 410 | 61 079 | 0,53% | Acciones |
| BURNEY CO/ | $2 181 683 | 55 769 | 0,48% | Acciones |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $2 159 424 | 55 200 | 0,48% | Acciones |
| OMERS ADMINISTRATION Corp | $2 030 328 | 51 900 | 0,45% | Acciones |
| PRINCIPAL FINANCIAL GROUP INC | $2 017 066 | 51 561 | 0,45% | Acciones |
| Woodline Partners LP | $1 956 000 | 50 000 | 0,43% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $1 920 636 | 49 096 | 0,43% | Acciones |
| SEGALL BRYANT & HAMILL, LLC | $1 794 747 | 45 878 | 0,40% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 635 216 | 41 800 | 0,36% | Opción de venta |
| WELLS FARGO & COMPANY/MN | $1 528 927 | 39 083 | 0,34% | Acciones |
| ALPS ADVISORS INC | $1 488 633 | 38 053 | 0,33% | Acciones |
| Bank of New York Mellon Corp | $1 393 963 | 35 633 | 0,31% | Acciones |
| Virtus Investment Advisers, LLC | $1 384 848 | 35 400 | 0,31% | Acciones |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $1 370 334 | 35 029 | 0,30% | Acciones |
| Trexquant Investment LP | $1 312 945 | 33 562 | 0,29% | Acciones |
| SIERRA SUMMIT ADVISORS LLC | $1 246 990 | 31 876 | 0,28% | Acciones |
| CITIGROUP INC | $1 232 436 | 31 504 | 0,27% | Acciones |
| CREDIT AGRICOLE S A | $1 126 656 | 28 800 | 0,25% | Acciones |
| RHUMBLINE ADVISERS | $1 016 483 | 25 984 | 0,23% | Acciones |
| CITADEL ADVISORS LLC | $962 352 | 24 600 | 0,21% | Opción de compra |
| Vanguard Global Advisers, LLC | $949 247 | 24 265 | 0,21% | Acciones |
| Engineers Gate Manager LP | $933 638 | 23 866 | 0,21% | Acciones |
| AXA Investment Managers S.A. | $923 388 | 32 594 | 0,20% | Acciones |
| DIADEMA PARTNERS LP | $892 562 | 22 816 | 0,20% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $866 172 | 32 033 | 0,19% | Acciones |
| MARSHALL WACE, LLP | $863 770 | 22 080 | 0,19% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $847 730 | 21 670 | 0,19% | Acciones |
| STRS OHIO | $813 696 | 20 800 | 0,18% | Acciones |
| Man Group plc | $813 540 | 20 796 | 0,18% | Acciones |
| Quantinno Capital Management LP | $802 116 | 20 504 | 0,18% | Acciones |
| HSBC HOLDINGS PLC | $744 752 | 18 577 | 0,17% | Acciones |
| CANADA PENSION PLAN INVESTMENT BOARD | $735 456 | 18 800 | 0,16% | Acciones |
| Rafferty Asset Management, LLC | $707 094 | 18 075 | 0,16% | Acciones |
| DEUTSCHE BANK AG\ | $702 478 | 17 957 | 0,16% | Acciones |
| MACKENZIE FINANCIAL CORP | $701 109 | 17 922 | 0,16% | Acciones |
| TWO SIGMA ADVISERS, LP | $693 760 | 16 198 | 0,15% | Acciones |
| Aquatic Capital Management LLC | $674 155 | 17 233 | 0,15% | Acciones |
| CITADEL ADVISORS LLC | $668 952 | 17 100 | 0,15% | Opción de venta |
| WELLINGTON MANAGEMENT GROUP LLP | $632 062 | 16 157 | 0,14% | Acciones |
| BOKF, NA | $598 771 | 15 306 | 0,13% | Acciones |
| NJ State Employees Deferred Compensation Plan | $566 600 | 20 000 | 0,13% | Acciones |
| Pale Fire Capital SE | $557 538 | 14 252 | 0,12% | Acciones |
| AVIVA PLC | $529 607 | 13 538 | 0,12% | Acciones |
| BARCLAYS PLC | $524 091 | 13 397 | 0,12% | Acciones |
| Graham Capital Management, L.P. | $471 396 | 12 050 | 0,10% | Acciones |
| MetLife Investment Management, LLC | $447 063 | 11 428 | 0,10% | Acciones |
| OSAIC HOLDINGS, INC. | $436 075 | 11 151 | 0,10% | Acciones |
| Nuveen Asset Management, LLC | $387 751 | 23 053 | 0,09% | Acciones |
| WOLVERINE TRADING, LLC | $376 625 | 13 100 | 0,08% | Opción de compra |
| PROFUND ADVISORS LLC | $358 887 | 9 174 | 0,08% | Acciones |
| PRUDENTIAL FINANCIAL INC | $337 527 | 8 628 | 0,07% | Acciones |
| Advantage Alpha Capital Partners LP | $334 407 | 11 804 | 0,07% | Acciones |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | $296 099 | 7 569 | 0,07% | Acciones |
| JANE STREET GROUP, LLC | $285 576 | 7 300 | 0,06% | Opción de compra |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $280 177 | 7 162 | 0,06% | Acciones |
| Invesco Ltd. | $277 126 | 7 084 | 0,06% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $275 248 | 7 036 | 0,06% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $243 053 | 6 213 | 0,05% | Acciones |
| Caprock Group, LLC | $238 828 | 6 105 | 0,05% | Acciones |
| Jump Financial, LLC | $238 632 | 6 100 | 0,05% | Acciones |
| Persistent Asset Partners Ltd | $227 718 | 5 821 | 0,05% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $227 600 | 5 818 | 0,05% | Acciones |
| Nuveen, LLC | $226 231 | 5 783 | 0,05% | Acciones |
| Russell Investments Group, Ltd. | $210 504 | 5 381 | 0,05% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $133 908 | 3 423 | 0,03% | Acciones |
| MORGAN STANLEY | $131 678 | 3 366 | 0,03% | Acciones |
| AlphaQuest LLC | $127 462 | 2 976 | 0,03% | Acciones |
Informantes de la empresa 41 insiders · 19 directivos · 21 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Raul R Rodriguez | CEO, President | 17 de junio de 2026 A | 279 593 | 0 | 0 | $0 |
| James M Gower | CEO & Board Chairman | 27 de febrero de 2014 A | 180 676 | 0 | 0 | $0 |
| Dean L Schorno | EVP & Chief Financial Officer | 17 de junio de 2026 A | 78 790 | 0 | 0 | $0 |
| Ryan D Maynard | EVP & CFO | 3 de noviembre de 2017 M | 0 | 0 | 0 | $0 |
| James H Welch | CFO, VP & Secretary | 25 de enero de 2006 A | 3 757 | 0 | 0 | $0 |
| Lisa Rojkjaer | EVP, Chief Medical Officer | 17 de junio de 2026 A | 34 003 | 0 | 0 | $0 |
| David A Santos | EVP, Chief Commercial Officer | 17 de junio de 2026 A | 61 996 | 0 | 0 | $0 |
| Raymond J. Furey | EVP, GC, CCO & Corp Sec | 17 de junio de 2026 A | 50 936 | 0 | 0 | $0 |
| Wolfgang Dummer | EVP & CMO | 2 de febrero de 2023 S | 72 459 | 0 | 0 | $0 |
| Dolly Vance | EVP Corp. Affairs, G.C., Sect. | 14 de septiembre de 2022 A | 575 | 0 | 0 | $0 |
| Nelson Cabatuan | VP,Finance & Princ.Acctg. Off. | 14 de mayo de 2020 A | 58 | 0 | 0 | $0 |
| Eldon C. Mayer III | EVP & Chief Commercial Officer | 18 de noviembre de 2019 A | 215 000 | 0 | 0 | $0 |
| Joseph Lasaga | Sr.VP Bus.Dev.Alliance Mgmt. | 18 de noviembre de 2019 A | — | 0 | 0 | $0 |
| Esteban Masuda | Sr. VP Research | 18 de noviembre de 2019 S | — | 0 | 0 | $0 |
| Stacy Markel | EVP Human Resources | 20 de marzo de 2019 A | — | 0 | 0 | $0 |
| Anne-Marie Duliege | EVP & Chief Medical Officer | 20 de marzo de 2019 A | 0 | 0 | 0 | $0 |
| Donald G Payan | EVP, Pres. Discovery&Research | 30 de agosto de 2016 S | 53 031 | 0 | 0 | $0 |
| Elliot B Grossbard | EVP, CMO | 26 de enero de 2016 A | 2 000 | 0 | 0 | $0 |
| Robin D G Cooper | Sr. V.P. Pharmaceutical Scs. | 31 de enero de 2008 A | 9 000 | 0 | 0 | $0 |
| Kamil Ali-Jackson | Consejero | 22 de junio de 2026 S | 10 125 | 0 | 2 | $-160 425 |
| Alison L. Hannah | Consejero | 15 de mayo de 2026 A | 16 375 | 0 | 0 | $0 |
| Mark W Frohlich | Consejero | 15 de mayo de 2026 A | 7 000 | 0 | 0 | $0 |
| Jane Wasman | Consejero | 15 de mayo de 2026 A | 18 250 | 0 | 0 | $0 |
| Anthony Gregg Lapointe | Consejero | 15 de mayo de 2026 A | 18 250 | 0 | 0 | $0 |
| MILLER MICHAEL PATRICK | Consejero | 15 de mayo de 2026 A | 5 937 | 0 | 0 | $0 |
| Walter H Moos | Consejero | 15 de mayo de 2026 A | 18 472 | 0 | 1 | $-145 440 |
| Brian L. Kotzin | Consejero | 25 de mayo de 2024 A | 100 000 | 0 | 0 | $0 |
| LYONS GARY A | Consejero | 26 de mayo de 2023 A | 75 000 | 0 | 0 | $0 |
| Keith Katkin | Consejero | 19 de mayo de 2021 A | 25 000 | 0 | 0 | $0 |
| Bradford S Goodwin | Consejero | 19 de mayo de 2021 A | 35 000 | 0 | 0 | $0 |
| Peter S Ringrose | Consejero | 17 de mayo de 2018 A | — | 0 | 0 | $0 |
| SHERWIN STEPHEN A | Consejero | 11 de mayo de 2016 A | — | 0 | 0 | $0 |
| Hollings Renton | Consejero | 15 de mayo de 2013 A | — | 0 | 0 | $0 |
| Jean Deleage | Consejero | 28 de mayo de 2010 A | 697 | 0 | 0 | $0 |
| Alan D Frazier | Consejero | 7 de agosto de 2006 A | 10 905 | 0 | 0 | $0 |
| Nicholas J Simon III | Consejero | 3 de junio de 2005 A | 0 | 0 | 0 | $0 |
| Dennis Henner | Consejero | 5 de enero de 2005 S | 0 | 0 | 0 | $0 |
| Michael Steinmetz | Propietario del 10% | 2 de agosto de 2004 S | 1 833 597 | 0 | 0 | $0 |
| Nicholas Galakatos | Propietario del 10% | 2 de julio de 2004 S | 1 833 597 | 0 | 0 | $0 |
| Luke Evnin | Propietario del 10% | 2 de julio de 2004 S | 1 833 597 | 0 | 0 | $0 |
| ANSBERT GADICKE | Propietario del 10% | 2 de julio de 2004 J | 0 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 5 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Persona informante no revelada, Persona informante no revelada, Persona informante no revelada | 27 de enero de 2005 | — | Presentación inicial | Inversión pasiva | SEC |
| I.R.S.Identification Nos. of above persons (entities only). FRAZIER HEALTHCARE II, L.P., I.R.S.Identification Nos. of above persons (entities only). FHM II, L.L.C., I.R.S.Identification Nos. of above persons (entities only). FRAZIER HEALTHCARE IV, L.P., I.R.S.Identification Nos. of above persons (entities only). FRAZIER AFFILIATES IV, L.P.., I.R.S.Identification Nos. of above persons (entities only). FHM IV, L.P., I.R.S.Identification Nos. of above persons (entities only). FHM IV, L.L.C., I.R.S.Identification Nos. of above persons (entities only). FRAZIER MANAGEMENT, L.L.C., I.R.S.Identification Nos. of above persons (entities only). FRAZIER & COMPANY, INC., I.R.S.Identification Nos. of above persons (entities only). ALAN D. FRAZIER | 14 de abril de 2004 | — | Presentación inicial | Inversión pasiva | SEC |
| Persona informante no revelada, Persona informante no revelada, Persona informante no revelada, Persona informante no revelada | 7 de julio de 2003 | — | Presentación inicial | Campaña de la junta directiva | SEC |
| MPM BioVentures III, L.P., MPM BioVentures III-QP, L.P., MPM BioVentures III Parallel Fund, L.P., MPM BioVentures III GmbH & Co. Beteiligungs KG, MPM Asset Management Investors 2003 BVIII, LLC, MPM BioEquities Master Fund, L.P., MPM BioVentures III GP, LP, MPM BioVentures III LLC, MPM BioEquities GP, LP, MPM BioEquities GP, LLC, Luke Evnin, Ansbert Gadicke, Nicholas Galakatos, Dennis Henner, Robert Liptak, Nick Simon, III, Michael Steinmetz, Kurt von Emster, Kurt Wheeler | 7 de julio de 2003 | — | Presentación inicial | Campaña de la junta directiva | SEC |
| MPM Bio Ventures III, L.P., MPM Bio Ventures III-QP, L.P., MPM Bio Ventures III Parallel Fund, L.P., MPM Bio Ventures III GmbH & Co. Beteiligungs KG, MPM Asset Management Investors 2003 BVIII, LLC, MPM BioEquities Master Fund, L.P., MPM Bio Ventures III GP, L.P., MPM Bio Ventures III LLC, MPM BioEquities GP, L.P., MPM BioEquities GP, LLC, Luke Evnin, Ansbert Gadicke, Nicholas Galakatos, Dennis Henner, Robert Liptak, Nicholas Simon, III, Michael Steinmetz, Kurt von Emster, Kurt Wheeler | 14 de mayo de 2003 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 51 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IDNA · iShares Trust | 0,77% | 38 807 SH | 8 de agosto de 2026 | Diario |
| QQQS · Invesco Exchange-Traded Fund Trust … | 0,65% | 3 672 SH | 8 de agosto de 2026 | Diario |
| AFSM · First Trust Exchange-Traded Fund VI… | 0,53% | 17 221 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,52% | 6 766 NS | 30 de abril de 2026 | N-PORT |
| BRNY · EA Series Trust | 0,45% | 86 788 NS | 30 de abril de 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 0,36% | 19 042 NS | 31 de mayo de 2026 | N-PORT |
| JSML · Janus Detroit Street Trust | 0,34% | 37 605 NS | 30 de abril de 2026 | N-PORT |
| JSMD · Janus Detroit Street Trust | 0,30% | 102 534 NS | 30 de abril de 2026 | N-PORT |
| BFOR · ALPS ETF Trust | 0,27% | 19 079 NS | 31 de mayo de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,23% | 40 551 NS | 30 de abril de 2026 | N-PORT |
| IWC · iShares Trust | 0,16% | 62 571 SH | 8 de agosto de 2026 | Diario |
| JPSE · J.P. Morgan Exchange-Traded Fund Tr… | 0,15% | 30 071 NS | 30 de abril de 2026 | N-PORT |
| VFMF · VANGUARD WELLINGTON FUND | 0,13% | 23 978 SH | 8 de agosto de 2026 | Diario |
| CALF · Pacer Funds Trust | 0,10% | 113 280 NS | 30 de abril de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,07% | 23 773 NS | 31 de mayo de 2026 | N-PORT |
| AVUV · AMERICAN CENTURY ETF TRUST | 0,07% | 594 889 NS | 31 de mayo de 2026 | N-PORT |
| IBB · iShares Trust | 0,05% | 132 606 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,05% | 1 005 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,05% | 27 549 SH | 8 de agosto de 2026 | Diario |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,05% | 15 998 SH | 8 de agosto de 2026 | Diario |
| IWN · iShares Trust | 0,05% | 170 765 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,03% | 672 NS | 31 de mayo de 2026 | N-PORT |
| IWM · iShares Trust | 0,02% | 472 222 SH | 8 de agosto de 2026 | Diario |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,02% | 20 787 NS | 31 de mayo de 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,02% | 14 496 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 105 855 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,02% | 7 831 NS | 30 de abril de 2026 | N-PORT |
| TECB · iShares Trust | 0,02% | 1 868 SH | 8 de agosto de 2026 | Diario |
| ITWO · ProShares Trust | 0,01% | 843 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,01% | 58 389 NS | 30 de abril de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 89 359 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 212 359 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 54 159 SH | 8 de agosto de 2026 | Diario |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,01% | 622 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,01% | 659 NS | 31 de mayo de 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,01% | 1 135 NS | 31 de mayo de 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 665 NS | 31 de mayo de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,01% | 700 NS | 30 de abril de 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 18 569 NS | 31 de mayo de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 677 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 17 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 2 458 NS | 30 de abril de 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 6 483 SH | 8 de agosto de 2026 | Diario |
| DFAC · Dimensional ETF Trust | 0,00% | 17 507 NS | 30 de abril de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 22 837 SH | 8 de agosto de 2026 | Diario |
| DFAU · Dimensional ETF Trust | 0,00% | 3 011 NS | 30 de abril de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 5 798 NS | 30 de abril de 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 10 304 NS | 31 de mayo de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 555 846 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 1 629 SH | 8 de agosto de 2026 | Diario |