OLMA Olema Pharmaceuticals, Inc. - Common Stock
OLMA Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
OLMA Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
OLMA Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 6 33,3%
- Compra 10 55,6%
- Mantener 2 11,1%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
10 analistas · 2026-08-17Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.61 | $-0.56 | -0.05% |
| 31 de marzo de 2026 | $-0.52 | $-0.54 | 0.02% |
| 31 de diciembre de 2025 | $-0.50 | $-0.54 | 0.04% |
| 30 de septiembre de 2025 | $-0.49 | $-0.49 | 0.00% |
| 30 de junio de 2025 | $-0.51 | $-0.38 | -0.13% |
| 31 de marzo de 2025 | $-0.36 | $-0.52 | 0.16% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| OLMA | $2.03B | -13.4 | — | — | -39.4% | — |
| ARDX | $1.42B | -22.4 | 22.1% | -15.1% | -40.2% | — |
| CADL | $310M | -7.8 | — | — | -53.7% | — |
| DSGN | $567M | -7.7 | — | — | -32.8% | — |
| CLYM | $191M | -4.5 | — | — | -34.6% | — |
| IMMX | $277M | -5.9 | — | — | -59.8% | — |
| FTH | — | — | — | — | — | — |
| FDMT | $432M | -3.1 | 230194.6% | -164.4% | -30.2% | — |
| RIGL | $784M | 2.2 | 64.1% | 124.7% | 155.1% | — |
| AURA | $347M | -3.1 | -29.7% | -1601.4% | -68.2% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 15
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $158M | $125M | $86M | $82M | $51M | $14M | |
| SG&A Expense | $21M | $18M | $19M | $25M | $20M | $8M | |
| Operating Expenses | $179M | $142M | $105M | $107M | $71M | $22M | |
| Operating Income | $-179M | $-142M | $-105M | $-107M | $-71M | $-22M | |
| Interest Expense | · | · | · | · | · | $653.0K | |
| Interest Income | $16M | $13M | $8M | $2M | $442.0K | $60.0K | |
| Other Non-op | $23.0K | $102.0K | $-19.0K | $-27.0K | $-47.0K | · | |
| Pretax Income | $-162M | $-129M | · | · | · | · | |
| Income Tax | $3.0K | $2.0K | $2.0K | $1.0K | · | · | |
| Net Income | $-162M | $-129M | $-97M | $-105M | $-71M | $-22M | |
| EPS (Basic) | $-1.87 | $-2.20 | $-2.14 | $-2.62 | $-1.80 | $-3.42 | |
| EPS (Diluted) | $-1.87 | $-2.20 | $-2.14 | $-2.62 | $-1.80 | $-3.42 | |
| Shares (Basic) | 87,006,027 | 58,743,522 | 45,247,098 | 39,995,460 | 39,524,272 | 7,021,468 | |
| Shares (Diluted) | 87,006,027 | 58,743,522 | 45,247,098 | 39,995,460 | 39,524,272 | 7,021,468 | |
| EBITDA | $-178M | $-142M | $-105M | $-107M | $-71M | · |
Balance general 20
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $48M | $139M | $69M | $24M | $14M | $339M | |
| Short-term Investments | $457M | $295M | $193M | $181M | $273M | · | |
| Prepaid Expense | $10M | $4M | $5M | $4M | $3M | $4M | |
| Current Assets | $515M | $438M | $267M | $209M | $291M | $342M | |
| PP&E (Net) | $274.0K | $746.0K | $968.0K | $1M | $1M | $75.0K | |
| PP&E (Gross) | · | · | · | $2M | $2M | $137.0K | |
| Accum. Depreciation | · | · | · | $581.0K | $224.0K | $62.0K | |
| Other Non-current Assets | · | $15.0K | · | $3M | $540.0K | $510.0K | |
| Total Assets | $533M | $451M | $277M | $216M | $296M | $343M | |
| Accounts Payable | $9M | $4M | $3M | $374.0K | $23.0K | $719.0K | |
| Current Liabilities | $52M | $42M | $22M | $17M | $9M | $5M | |
| Capital Leases | $69.0K | $257.0K | $1M | $2M | $2M | · | |
| Total Liabilities | $55M | $42M | $23M | $18M | $11M | $5M | |
| Common Stock | $8.0K | $7.0K | $4.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $1.08B | $844M | $559M | $408M | $389M | $371M | |
| Retained Earnings | $-598M | $-435M | $-306M | $-209M | $-104M | $-33M | |
| AOCI | $621.0K | $143.0K | $347.0K | $-2M | $-149.0K | · | |
| Stockholders' Equity | $479M | $409M | $254M | $198M | $285M | $338M | |
| Liabilities + Equity | $533M | $451M | $277M | $216M | $296M | $343M | |
| Shares Outstanding | 81,376,449 | 74,312,608 | 54,992,784 | 40,287,097 | 39,797,263 | 39,308,238 |
Flujo de Efectivo 9
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $490.0K | $393.0K | $377.0K | $357.0K | $163.0K | $11.0K | |
| Stock-based Comp | $18M | $23M | $17M | $19M | $16M | $3M | |
| Other Non-cash | $-2M | $2M | $-5M | $4M | $4M | · | |
| Operating Cash Flow | $-147M | $-104M | $-84M | $-82M | $-51M | $-20M | |
| CapEx | · | $159.0K | · | $363.0K | $2M | $56.0K | |
| Investing Cash Flow | $-156M | $-94M | $-5M | $91M | $-275M | $-56.0K | |
| Financing Cash Flow | $211M | $269M | $133M | $476.0K | $1M | $358M | |
| Net Change in Cash | $-91M | $71M | $45M | $10M | $-325M | $338M | |
| Free Cash Flow | · | $-105M | · | $-82M | $-52M | · |
Rentabilidad 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -33.0% | -35.6% | -39.2% | -41.0% | -22.3% | · | |
| ROE | -39.4% | -42.6% | -36.5% | -50.5% | -24.3% | · | |
| ROIC | -37.3% | · | · | · | · | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 10.0 | 10.5 | 12.3 | 12.6 | 32.2 | · | |
| Quick Ratio | 9.8 | 10.4 | 12.1 | 12.4 | 31.8 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-162M | $-129M | $-97M | $-105M | $-71M | $-22M | |
| Market Cap | $2.03B | $433M | $772M | $99M | $373M | · | |
| P/E | -13.4 | -2.6 | -6.6 | -0.9 | -5.2 | -14.1 | |
| P/B | 4.3 | 1.1 | 3.0 | 0.5 | 1.3 | · | |
| P / Tangible Book | 4.3 | 1.1 | 3.0 | 0.5 | 1.3 | · | |
| P / Cash Flow | -13.9 | -4.2 | -9.2 | -1.2 | -7.3 | · | |
| P / FCF | · | -4.1 | · | -1.2 | -7.1 | · | |
| Earnings Yield | -7.5% | -37.7% | -15.2% | -106.9% | -19.2% | -7.1% |
Estado de resultados 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $58M | $49M | $43M | $40M | $44M | $31M | $32M | $33M | $29M | $30M | $26M | $19M | $18M | $23M | $22M | $18M | |
| SG&A Expense | $9M | $9M | $7M | $6M | $4M | $4M | $4M | $4M | $4M | $4M | $5M | $4M | $4M | $7M | $6M | $6M | |
| Operating Expenses | $67M | $58M | $50M | $46M | $48M | $35M | $37M | $38M | $34M | $34M | $30M | $23M | $22M | $30M | $27M | $23M | |
| Operating Income | $-67M | $-58M | $-50M | $-46M | $-48M | $-35M | $-37M | $-38M | $-34M | $-34M | $-30M | $-23M | $-22M | $-30M | $-27M | $-23M | |
| Interest Income | $5M | $5M | $4M | $4M | $4M | $5M | $3M | $3M | $3M | $3M | $4M | $2M | $2M | $1M | $973.0K | $622.0K | |
| Other Non-op | $-528.0K | $121.0K | $13.0K | $12.0K | $38.0K | $-40.0K | $-93.0K | $138.0K | $40.0K | $17.0K | $93.0K | $-79.0K | $-44.0K | $11.0K | $67.0K | $-120.0K | |
| Net Income | $-63M | $-53M | $-46M | $-42M | $-44M | $-30M | $-34M | $-35M | $-30M | $-31M | $-27M | $-22M | $-20M | $-28M | $-26M | $-23M | |
| EPS (Basic) | $-0.61 | $-0.52 | $-0.51 | $-0.49 | $-0.51 | $-0.36 | $-0.50 | $-0.60 | $-0.54 | $-0.56 | $-0.47 | $-0.48 | $-0.49 | $-0.70 | $-0.65 | $-0.57 | |
| EPS (Diluted) | $-0.61 | $-0.52 | $-0.51 | $-0.49 | $-0.51 | $-0.36 | $-0.50 | $-0.60 | $-0.54 | $-0.56 | $-0.47 | $-0.48 | $-0.49 | $-0.70 | $-0.65 | $-0.57 | |
| Shares (Basic) | 104,453,732 | 102,800,098 | -169,649,843 | 85,732,221 | 85,497,426 | 85,426,223 | -110,376,007 | 57,262,803 | 56,282,402 | 55,574,324 | -80,804,850 | 44,977,161 | 40,720,294 | 40,354,493 | -79,793,579 | 40,036,201 | |
| Shares (Diluted) | 104,453,732 | 102,800,098 | -169,649,843 | 85,732,221 | 85,497,426 | 85,426,223 | -110,376,007 | 57,262,803 | 56,282,402 | 55,574,324 | -80,804,850 | 44,977,161 | 40,720,294 | 40,354,493 | -79,793,579 | 40,036,201 | |
| EBITDA | $-67M | $-58M | · | $-46M | $-48M | $-35M | · | $-38M | $-34M | $-34M | · | $-23M | $-22M | $-30M | · | $-23M |
Balance general 20
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $49M | $53M | $48M | $35M | $52M | $51M | $139M | $36M | $17M | $34M | $69M | $117M | $35M | $41M | $24M | $27M | |
| Short-term Investments | $412M | $453M | $457M | $294M | $309M | $342M | $295M | $179M | $222M | $215M | $193M | $159M | $132M | $145M | $181M | $196M | |
| Prepaid Expense | $9M | $8M | $10M | $5M | $6M | $4M | $4M | $3M | $3M | $3M | $5M | $5M | $4M | $3M | $4M | $2M | |
| Current Assets | $470M | $513M | $515M | $334M | $368M | $397M | $438M | $218M | $242M | $252M | $267M | $282M | $172M | $189M | $209M | $225M | |
| PP&E (Net) | $382.0K | $356.0K | $274.0K | $486.0K | $560.0K | $653.0K | $746.0K | $849.0K | $945.0K | $1M | $968.0K | $1M | $1M | $1M | $1M | $1M | |
| PP&E (Gross) | · | · | · | · | · | · | · | · | · | · | · | $2M | $2M | $2M | · | $2M | |
| Accum. Depreciation | · | · | · | · | · | · | · | · | · | · | · | $698.0K | $744.0K | $681.0K | · | $484.0K | |
| Other Non-current Assets | · | · | · | · | $15.0K | $14.0K | $15.0K | $15.0K | $16.0K | · | · | · | · | $3M | · | $3M | |
| Total Assets | $487M | $531M | $533M | $352M | $382M | $410M | $451M | $230M | $255M | $264M | $277M | $293M | $178M | $196M | $216M | $232M | |
| Accounts Payable | $2M | $4M | $9M | $3M | $934.0K | $151.0K | $4M | $3M | $4M | $8M | $3M | $2M | $2M | $681.0K | $374.0K | $14.0K | |
| Current Liabilities | $53M | $47M | $52M | $42M | $33M | $26M | $42M | $31M | $27M | $26M | $22M | $16M | $15M | $19M | $17M | $13M | |
| Capital Leases | $0 | $0 | $69.0K | $310.0K | $602.0K | $123.0K | $257.0K | $562.0K | $859.0K | $1M | $1M | $2M | $1M | $1M | $2M | $2M | |
| Total Liabilities | $56M | $50M | $55M | $45M | $37M | $26M | $42M | $31M | $27M | $27M | $23M | $18M | $16M | $21M | $18M | $14M | |
| Common Stock | $8.0K | $8.0K | $8.0K | $7.0K | $7.0K | $7.0K | $7.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $3.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $1.15B | $1.13B | $1.08B | $858M | $854M | $849M | $844M | $600M | $594M | $573M | $559M | $554M | $419M | $413M | $408M | $403M | |
| Retained Earnings | $-714M | $-651M | $-598M | $-551M | $-509M | $-465M | $-435M | $-402M | $-367M | $-337M | $-306M | $-279M | $-257M | $-237M | $-209M | $-183M | |
| AOCI | $-947.0K | $-460.0K | $621.0K | $526.0K | $314.0K | $420.0K | $143.0K | $464.0K | $-118.0K | $-10.0K | $347.0K | $-241.0K | $-518.0K | $-978.0K | $-2M | $-3M | |
| Stockholders' Equity | $431M | $480M | $479M | $307M | $345M | $383M | $409M | $199M | $227M | $236M | $254M | $275M | $162M | $175M | $198M | $218M | |
| Liabilities + Equity | $487M | $531M | $533M | $352M | $382M | $410M | $451M | $230M | $255M | $264M | $277M | $293M | $178M | $196M | $216M | $232M | |
| Shares Outstanding | 87,452,166 | 87,332,971 | 81,376,449 | 68,652,730 | 68,627,886 | 68,333,065 | 74,312,608 | 57,288,319 | 57,246,411 | 55,867,863 | 54,992,784 | 54,601,516 | 41,122,482 | 40,438,320 | 40,287,097 | 40,084,568 |
Flujo de Efectivo 9
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $102.0K | $119.0K | $187.0K | $43.0K | $132.0K | $128.0K | $116.0K | $95.0K | $94.0K | $88.0K | $88.0K | $90.0K | $99.0K | $100.0K | $97.0K | $91.0K | |
| Stock-based Comp | $13M | $10M | $4M | $4M | $5M | $4M | $6M | $6M | $6M | $5M | $4M | $4M | $4M | $5M | $5M | $4M | |
| Other Non-cash | · | $-3M | · | · | · | $-18M | · | · | · | $2M | · | · | · | $3M | · | · | |
| Operating Cash Flow | $-46M | $-46M | $-38M | $-35M | $-30M | $-44M | $-26M | $-27M | $-28M | $-23M | $-18M | $-23M | $-22M | $-20M | $-20M | $-18M | |
| CapEx | · | · | · | $0 | · | · | $0 | $0 | $6.0K | $153.0K | · | · | · | · | $173.0K | $139.0K | |
| Investing Cash Flow | $41M | $5M | $-162M | $17M | $34M | $-45M | $-114M | $46M | $-5M | $-20M | $-31M | $-25M | $14M | $37M | $16M | $20M | |
| Financing Cash Flow | $1M | $46M | $214M | $41.0K | $-3M | $222.0K | $244M | $92.0K | $16M | $9M | $523.0K | $131M | $2M | $220.0K | $273.0K | $106.0K | |
| Net Change in Cash | $-4M | $4M | $13M | $-17M | $2M | $-89M | $104M | $19M | $-17M | $-35M | $-49M | $82M | $-6M | $17M | $-3M | $2M | |
| Free Cash Flow | · | · | · | · | · | · | · | · | · | $-24M | · | · | · | · | · | · |
Rentabilidad 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -14.5% | -11.3% | · | -14.5% | -13.8% | -9.0% | · | -13.2% | -14.1% | -13.5% | · | -8.2% | -9.4% | -12.0% | · | -8.4% | |
| ROE | -16.3% | -12.3% | · | -16.7% | -15.3% | -9.8% | · | -14.6% | -15.6% | -15.1% | · | -8.7% | -10.1% | -12.9% | · | -8.8% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 8.9 | 10.9 | · | 8.0 | 11.1 | 15.2 | · | 7.1 | 9.1 | 9.6 | · | 17.7 | 11.6 | 9.8 | · | 17.9 | |
| Quick Ratio | 8.7 | 10.7 | · | 7.9 | 10.9 | 15.1 | · | 7.0 | 9.0 | 9.5 | · | 17.3 | 11.3 | 9.6 | · | 17.7 |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-202M | $-169M | · | $-151M | $-139M | $-126M | · | $-117M | $-103M | $-101M | · | $-93M | $-104M | $-107M | · | $-96M | |
| Market Cap | $1.09B | $1.30B | · | $672M | $292M | $257M | · | $684M | $619M | $632M | · | $674M | $371M | $140M | · | $111M | |
| P/E | -5.9 | -7.9 | · | -5.0 | -2.1 | -1.8 | · | -5.5 | -5.2 | -5.1 | · | -5.5 | -3.5 | -1.3 | · | -1.1 | |
| P/B | 2.5 | 2.7 | · | 2.2 | 0.8 | 0.7 | · | 3.4 | 2.7 | 2.7 | · | 2.5 | 2.3 | 0.8 | · | 0.5 | |
| P / Tangible Book | 2.5 | 2.7 | · | 2.2 | 0.8 | 0.7 | · | 3.4 | 2.7 | 2.7 | · | 2.5 | 2.3 | 0.8 | · | 0.5 | |
| P / Cash Flow | · | -28.3 | · | · | · | -5.8 | · | · | · | -26.9 | · | · | · | -6.9 | · | · | |
| P / FCF | · | · | · | · | · | · | · | · | · | -26.7 | · | · | · | · | · | · | |
| Earnings Yield | -17.0% | -12.6% | · | -20.0% | -47.2% | -54.8% | · | -18.3% | -19.1% | -19.7% | · | -18.1% | -28.6% | -77.0% | · | -87.7% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-162M | $-129M | $-97M | $-105M | $-71M |
| EPS Diluido | $-1.87 | $-2.20 | $-2.14 | $-2.62 | $-1.80 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 10.0 | 10.5 | 12.3 | 12.6 | 32.2 |
| Ratio Rápido | 9.8 | 10.4 | 12.1 | 12.4 | 31.8 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | — | $-105M | — | $-82M | $-52M |
Últimas noticias Noticias recientes que mencionan a esta empresa
Mis Métricas Tu lista de seguimiento personal — filas seleccionadas de Fundamentales Completos
Elige las métricas que te importan — haz clic en el ➕ junto a cualquier fila en Fundamentales Completos arriba.
Tu selección se guarda y te sigue en todos los tickers.
Propietarios institucionales (13F) 201 declarantes · $1.1B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 32 (-26 vs trimestre anterior) | 37 (-10 vs trimestre anterior) | 69 (-1 vs trimestre anterior) | 61 (+6 vs trimestre anterior) | -1.6M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| FMR LLC | $109 938 906 | 8 788 082 | 10,35% | Acciones |
| Paradigm Biocapital Advisors LP | $108 468 906 | 8 670 576 | 10,21% | Acciones |
| Bain Capital Life Sciences Investors, LLC | $88 636 465 | 7 085 249 | 8,34% | Acciones |
| VANGUARD GROUP INC | $81 312 975 | 3 252 519 | 7,65% | Acciones |
| BVF INC/IL | $66 251 621 | 5 295 893 | 6,23% | Acciones |
| Siren, L.L.C. | $60 760 432 | 4 856 949 | 5,72% | Acciones |
| STATE STREET CORP | $53 993 886 | 4 316 058 | 5,08% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $41 798 625 | 3 341 217 | 3,93% | Acciones |
| Logos Global Management LP | $40 143 026 | 3 208 875 | 3,78% | Acciones |
| FRANKLIN RESOURCES INC | $29 375 482 | 2 348 160 | 2,76% | Acciones |
| Cormorant Asset Management, LP | $26 896 500 | 2 150 000 | 2,53% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $20 806 857 | 1 663 218 | 1,96% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $19 640 235 | 1 569 659 | 1,85% | Acciones |
| Deep Track Capital, LP | $18 765 000 | 1 500 000 | 1,77% | Acciones |
| GOLDMAN SACHS GROUP INC | $17 828 551 | 1 425 144 | 1,68% | Acciones |
| LIGHTSPEED MANAGEMENT COMPANY, L.L.C. | $16 954 790 | 1 355 299 | 1,60% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $16 685 012 | 1 333 734 | 1,57% | Acciones |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $15 012 000 | 1 200 000 | 1,41% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $14 154 239 | 1 131 434 | 1,33% | Acciones |
| Point72 Asset Management, L.P. | $13 397 572 | 1 070 949 | 1,26% | Acciones |
| Defilade Capital Management, L.P. | $11 568 723 | 924 758 | 1,09% | Acciones |
| AMERIPRISE FINANCIAL INC | $10 346 508 | 827 059 | 0,97% | Acciones |
| Woodline Partners LP | $9 395 385 | 751 030 | 0,88% | Acciones |
| Candriam S.C.A. | $9 387 633 | 751 133 | 0,88% | Acciones |
| Vivo Capital, LLC | $8 404 756 | 671 843 | 0,79% | Acciones |
| Qube Research & Technologies Ltd | $8 298 121 | 663 319 | 0,78% | Acciones |
| Squarepoint Ops LLC | $7 699 530 | 615 470 | 0,72% | Acciones |
| READYSTATE ASSET MANAGEMENT LP | $7 428 801 | 593 829 | 0,70% | Acciones |
| Jones Hill Capital LP | $7 182 817 | 574 166 | 0,68% | Acciones |
| Hudson Bay Capital Management LP | $7 085 664 | 566 400 | 0,67% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $6 484 458 | 518 342 | 0,61% | Acciones |
| CITADEL ADVISORS LLC | $5 710 252 | 456 455 | 0,54% | Acciones |
| Vestal Point Capital, LP | $5 236 073 | 418 551 | 0,49% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $5 192 338 | 415 055 | 0,49% | Acciones |
| Ikarian Capital, LLC | $4 794 845 | 383 281 | 0,45% | Acciones |
| SEB Asset Management AB | $4 246 649 | 339 461 | 0,40% | Acciones |
| Fisher Asset Management, LLC | $3 712 015 | 296 724 | 0,35% | Acciones |
| BANK OF AMERICA CORP /DE/ | $3 148 342 | 251 666 | 0,30% | Acciones |
| Rock Springs Capital Management LP | $2 942 077 | 235 178 | 0,28% | Acciones |
| Pier Capital, LLC | $2 760 944 | 220 699 | 0,26% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $2 589 432 | 206 989 | 0,24% | Acciones |
| Ikarian Capital, LLC | $2 502 000 | 200 000 | 0,24% | Opción de compra |
| Birchview Capital, LP | $2 489 490 | 199 000 | 0,23% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2 280 573 | 182 300 | 0,21% | Opción de venta |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | $2 024 566 | 161 836 | 0,19% | Acciones |
| HighVista Strategies LLC | $2 003 689 | 160 167 | 0,19% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $1 847 339 | 147 669 | 0,17% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $1 784 051 | 142 610 | 0,17% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 665 769 | 133 155 | 0,16% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 563 150 | 124 952 | 0,15% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $1 530 810 | 102 670 | 0,14% | Acciones |
| CITIGROUP INC | $1 514 173 | 121 037 | 0,14% | Acciones |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $1 393 142 | 114 192 | 0,13% | Acciones |
| TD Asset Management Inc | $1 328 737 | 106 214 | 0,13% | Acciones |
| Swiss National Bank | $1 313 550 | 105 000 | 0,12% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 297 287 | 103 700 | 0,12% | Opción de compra |
| Integral Health Asset Management, LLC | $1 251 000 | 100 000 | 0,12% | Acciones |
| RHUMBLINE ADVISERS | $1 245 110 | 99 530 | 0,12% | Acciones |
| Trexquant Investment LP | $1 156 074 | 92 412 | 0,11% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 125 775 | 89 990 | 0,11% | Acciones |
| XTX Topco Ltd | $1 119 958 | 89 525 | 0,11% | Acciones |
| TEMA ETFS LLC | $1 112 625 | 44 505 | 0,10% | Acciones |
| ALPS ADVISORS INC | $1 108 999 | 88 649 | 0,10% | Acciones |
| Bank of New York Mellon Corp | $1 071 482 | 85 650 | 0,10% | Acciones |
| BlackRock, Inc. | $1 070 956 | 85 608 | 0,10% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $1 026 195 | 82 030 | 0,10% | Acciones |
| ALGERT GLOBAL LLC | $1 012 409 | 80 928 | 0,10% | Acciones |
| FEDERATED HERMES, INC. | $966 598 | 77 266 | 0,09% | Acciones |
| AQR CAPITAL MANAGEMENT LLC | $960 893 | 76 810 | 0,09% | Acciones |
| Rafferty Asset Management, LLC | $944 780 | 75 522 | 0,09% | Acciones |
| ExodusPoint Capital Management, LP | $877 476 | 70 142 | 0,08% | Acciones |
| WELLS FARGO & COMPANY/MN | $833 691 | 66 642 | 0,08% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $827 699 | 66 163 | 0,08% | Acciones |
| NOMURA HOLDINGS INC | $825 660 | 66 000 | 0,08% | Opción de venta |
| LPL Financial LLC | $737 352 | 58 941 | 0,07% | Acciones |
| Quantinno Capital Management LP | $699 046 | 55 879 | 0,07% | Acciones |
| CITADEL ADVISORS LLC | $691 803 | 55 300 | 0,07% | Opción de compra |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $689 564 | 55 121 | 0,06% | Acciones |
| Swedbank AB | $689 301 | 55 100 | 0,06% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $688 050 | 55 000 | 0,06% | Opción de compra |
| Engineers Gate Manager LP | $669 961 | 53 554 | 0,06% | Acciones |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $626 000 | 50 000 | 0,06% | Acciones |
| PORTLAND INVESTMENT COUNSEL INC. | $625 500 | 50 000 | 0,06% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $582 668 | 39 079 | 0,05% | Acciones |
| MetLife Investment Management, LLC | $581 715 | 46 500 | 0,05% | Acciones |
| Headlands Technologies LLC | $515 937 | 41 242 | 0,05% | Acciones |
| NOMURA HOLDINGS INC | $505 404 | 40 400 | 0,05% | Opción de compra |
| PRUDENTIAL FINANCIAL INC | $494 896 | 39 560 | 0,05% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $482 811 | 38 594 | 0,05% | Acciones |
| PROFUND ADVISORS LLC | $479 871 | 38 359 | 0,05% | Acciones |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $469 901 | 37 562 | 0,04% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $451 586 | 36 098 | 0,04% | Acciones |
| JANUS HENDERSON GROUP PLC | $450 716 | 30 219 | 0,04% | Acciones |
| Aristotle Atlantic Partners, LLC | $448 609 | 35 860 | 0,04% | Acciones |
| NOMURA HOLDINGS INC | $423 539 | 33 856 | 0,04% | Acciones |
| Virtus Investment Advisers, LLC | $414 707 | 33 150 | 0,04% | Acciones |
| JANE STREET GROUP, LLC | $401 571 | 32 100 | 0,04% | Opción de compra |
| Seven Fleet Capital Management LP | $393 765 | 31 476 | 0,04% | Acciones |
| Invesco Ltd. | $389 224 | 31 113 | 0,04% | Acciones |
| Caption Management, LLC | $375 300 | 30 000 | 0,04% | Opción de compra |
Informantes de la empresa 19 insiders · 7 directivos · 12 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Sean Bohen | President and CEO | 1 de febrero de 2023 A | 52 514 | 0 | 0 | $0 |
| Naseem Zojwalla | Chief Medical Officer | 1 de febrero de 2023 A | — | 0 | 0 | $0 |
| David C. Myles | Chief Development Officer | 1 de febrero de 2023 A | 582 901 | 0 | 0 | $0 |
| Kinney Horn | Chief Business Officer | 1 de febrero de 2023 A | 2 458 | 0 | 0 | $0 |
| Shane William Charles Kovacs | Ch. Operating & Financial Off. | 1 de febrero de 2023 A | 381 197 | 0 | 0 | $0 |
| John B Moriarty | EVP, Ch. Legal Officer & Sec. | 1 de febrero de 2023 A | — | 0 | 0 | $0 |
| Peter J. Kushner | CHIEF SCIENTIFIC OFFICER | 1 de febrero de 2022 A | 1 431 672 | 0 | 0 | $0 |
| Cyrus Harmon | Consejero | 24 de julio de 2026 S | 702 770 | 0 | 2 | $-291 125 |
| Prakash Raman | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Hrustanovic Gorjan | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Yi Larson | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Graham Walmsley | Consejero | 18 de junio de 2026 A | 700 761 | 0 | 0 | $0 |
| Sandra Horning | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Scott J. Garland | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Ian T Clark | Consejero | 18 de junio de 2026 A | 0 | 0 | 3 | $-7 873 109 |
| Cynthia M Butitta | Consejero | 18 de junio de 2026 A | 83 876 | 0 | 0 | $0 |
| Andrew Rappaport | Consejero | 18 de junio de 2026 A | 0 | 0 | 0 | $0 |
| Frank Mccormick | Consejero | 23 de noviembre de 2020 C | 84 260 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | Propietario del 10% | 23 de noviembre de 2020 C | 1 725 406 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 2 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Logos Global Management LP, Logos Global Management GP LLC, Arsani William, Graham Walmsley, Logos Opportunities GP LLC, Logos GP LLC ×4 presentaciones | 13 de mayo de 2025 | 4,70% | Enmienda | Inversión pasiva | SEC |
| BIOTECHNOLOGY VALUE FUND, L.P., BVF I GP LLC, BIOTECHNOLOGY VALUE FUND II, L.P., BVF II GP LLC, BIOTECHNOLOGY VALUE TRADING FUND OS, L.P., BVF PARTNERS OS LTD., BVF GP HOLDINGS LLC, BVF PARTNERS L.P., BVF INC., MARK N. LAMPERT, GORJAN HRUSTANOVIC ×4 presentaciones | 4 de diciembre de 2024 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 45 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 0,66% | 81 077 NS | 31 de mayo de 2026 | N-PORT |
| CANC · Tema ETF Trust | 0,60% | 79 759 NS | 31 de mayo de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,39% | 141 558 NS | 30 de abril de 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 0,36% | 11 250 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,32% | 8 351 NS | 30 de abril de 2026 | N-PORT |
| BIB · ProShares Trust | 0,05% | 2 962 NS | 31 de mayo de 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,04% | 40 123 NS | 30 de abril de 2026 | N-PORT |
| RSSL · Global X Funds | 0,03% | 30 271 NS | 30 de abril de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,03% | 284 227 NS | 30 de abril de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,03% | 18 801 NS | 31 de mayo de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 3 287 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 247 403 NS | 31 de mayo de 2026 | N-PORT |
| UWM · ProShares Trust | 0,01% | 2 571 NS | 31 de mayo de 2026 | N-PORT |
| URTY · ProShares Trust | 0,01% | 2 602 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 17 308 NS | 30 de abril de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 2 374 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 65 NS | 31 de mayo de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 1 110 NS | 30 de abril de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,00% | 6 974 NS | 30 de abril de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,00% | 23 513 NS | 31 de mayo de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 21 603 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 75 925 NS | 30 de abril de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 16 063 NS | 30 de abril de 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 28 000 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | — | — | 15 de julio de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | — | — | 15 de julio de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | — | — | 30 de julio de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | — | — | 15 de julio de 2026 | Diario |
| VTWV · VANGUARD SCOTTSDALE FUNDS | — | — | 15 de julio de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | — | — | 15 de julio de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | — | — | 15 de julio de 2026 | Diario |
| ITOT · iShares Trust | — | — | 5 de agosto de 2026 | Diario |
| IWV · iShares Trust | — | — | 18 de agosto de 2026 | Diario |
| IWN · iShares Trust | — | — | 17 de agosto de 2026 | Diario |
| IWO · iShares Trust | — | — | 18 de agosto de 2026 | Diario |
| IWM · iShares Trust | — | — | 18 de agosto de 2026 | Diario |
| IBB · iShares Trust | — | — | 18 de agosto de 2026 | Diario |
| IWC · iShares Trust | — | — | 18 de agosto de 2026 | Diario |
| PRFZ · Invesco Exchange-Traded Fund Trust | — | — | 13 de julio de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | — | — | 20 de julio de 2026 | Diario |
| ISCB · iShares Trust | — | — | 5 de agosto de 2026 | Diario |
| ISCG · iShares Trust | — | — | 5 de agosto de 2026 | Diario |
| ISCV · iShares Trust | — | — | 5 de agosto de 2026 | Diario |
| WSML · iShares Trust | — | — | 5 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | — | — | 20 de julio de 2026 | Diario |