ACHV Achieve Life Sciences, Inc. - Common Shares
ACHV Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
ACHV Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
ACHV Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 3 20,0%
- Compra 11 73,3%
- Mantener 1 6,7%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
12 analistas · 2026-08-16Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 31 de marzo de 2026 | $-0.19 | $-0.31 | 0.12% |
| 31 de diciembre de 2025 | $-0.28 | $-0.28 | -0.00% |
| 30 de septiembre de 2025 | $-0.28 | $-0.26 | -0.02% |
| 30 de junio de 2025 | $-0.37 | $-0.37 | 0.00% |
| 31 de marzo de 2025 | $-0.37 | $-0.37 | 0.00% |
| 31 de diciembre de 2024 | $-0.36 | $-0.33 | -0.03% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| ACHV | — | -4.0 | — | — | — | — |
| RIGL | $784M | 2.2 | 64.1% | 124.7% | 155.1% | — |
| AURA | $347M | -3.1 | -29.7% | -1601.4% | -68.2% | — |
| MNPR | — | — | — | — | — | — |
| FDMT | $432M | -3.1 | 230194.6% | -164.4% | -30.2% | — |
| CTMX | $725M | — | -44.8% | -22.8% | -15.9% | — |
| NGNE | $319M | -4.9 | — | — | -33.6% | — |
| STTK | $231M | -5.2 | -82.5% | -4880.9% | -70.0% | — |
| RGNX | $733M | -3.8 | 104.5% | -113.8% | -122.5% | — |
| BBOT | $1.00B | -2.9 | — | — | -146.2% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 13
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | · | · | · | · | · | · | $0 | $0 | |
| R&D Expense | · | $23M | $16M | $30M | $24M | $7M | $10M | $6M | |
| SG&A Expense | · | $16M | $11M | $11M | $9M | $8M | $7M | $7M | |
| Operating Expenses | $55M | $39M | $27M | $41M | $33M | $15M | $17M | $13M | |
| Interest Expense | · | · | $3M | $2M | · | · | · | · | |
| Interest Income | $1M | $2M | $825.0K | $199.0K | $17.0K | $69.0K | $170.0K | $171.0K | |
| Other Non-op | $-36.0K | $-30.0K | $-9.0K | $40.0K | $-75.0K | $-49.0K | $-37.0K | $-45.0K | |
| Pretax Income | $-55M | $-40M | $-30M | $-42M | $-33M | $-15M | $-16M | $-13M | |
| Net Income | $-55M | $-40M | $-30M | $-42M | $-33M | $-15M | $-16M | $-13M | |
| EPS (Basic) | $-1.25 | $-1.24 | $-1.50 | $-4.00 | $-4.08 | $-5.42 | · | · | |
| EPS (Diluted) | $-1.25 | $-1.24 | $-1.50 | $-4.00 | $-4.08 | $-5.42 | · | · | |
| Shares (Basic) | 43,594,652 | 32,071,146 | 19,827,534 | 10,593,034 | 8,119,836 | 2,718,909 | · | · | |
| Shares (Diluted) | 43,594,652 | 32,071,146 | 19,827,534 | 10,593,034 | 8,119,836 | 2,718,909 | · | · |
Balance general 22
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $21M | $13M | $16M | $25M | $43M | $36M | $17M | $10M | |
| Short-term Investments | $15M | $22M | · | · | · | · | · | $5M | |
| Receivables | · | · | · | · | · | · | $8.0K | $7.0K | |
| Prepaid Expense | · | $2M | $1M | $2M | $1M | $1M | $670.0K | $926.0K | |
| Current Assets | $40M | $36M | $17M | $27M | $45M | $37M | $17M | $16M | |
| PP&E (Net) | $3.0K | $8.0K | $13.0K | $4.0K | $15.0K | $42.0K | $57.0K | $35.0K | |
| PP&E (Gross) | $256.0K | $256.0K | $256.0K | $303.0K | $302.0K | $674.0K | $657.0K | $755.0K | |
| Accum. Depreciation | $253.0K | $248.0K | $243.0K | $299.0K | $287.0K | $632.0K | $600.0K | $720.0K | |
| Goodwill | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | |
| Intangibles | $751.0K | $974.0K | $1M | $1M | $2M | $2M | $2M | $2M | |
| Other Non-current Assets | · | · | · | · | · | $187.0K | $187.0K | $118.0K | |
| Total Assets | $42M | $39M | $19M | $30M | $48M | $40M | $21M | $19M | |
| Accounts Payable | · | $2M | $618.0K | $2M | $841.0K | $332.0K | $859.0K | $144.0K | |
| Current Liabilities | $9M | $7M | $21M | $22M | $5M | $3M | $3M | $3M | |
| Capital Leases | $5.0K | $66.0K | $6.0K | $69.0K | $4.0K | $77.0K | $159.0K | $12.0K | |
| Total Liabilities | $20M | $18M | $21M | $22M | $19M | $3M | $3M | $3M | |
| Common Stock | $121.0K | $103.0K | $90.0K | $87.0K | $79.0K | $76.0K | $41.0K | $18.0K | |
| Retained Earnings | $-260M | $-206M | $-166M | $-136M | $-94M | $-60M | $-46M | $-25M | |
| AOCI | $10.0K | $31.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Stockholders' Equity | $22M | $21M | $-1M | $8M | $28M | $37M | $18M | $16M | |
| Liabilities + Equity | $42M | $39M | $19M | $30M | $48M | $40M | $21M | $19M | |
| Shares Outstanding | 53,233,988 | 34,685,072 | 21,165,760 | 17,897,029 | 9,453,542 | 6,111,735 | 1,474,258 | 6,721,117 |
Flujo de Efectivo 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| D&A | $228.0K | $229.0K | $228.0K | $236.0K | $250.0K | $255.0K | · | · | |
| Stock-based Comp | $9M | $5M | $3M | $3M | $2M | $1M | $1M | $854.0K | |
| Amort. of Intangibles | $200.0K | $200.0K | $200.0K | $200.0K | $200.0K | $200.0K | $200.0K | $200.0K | |
| Operating Cash Flow | $-49M | $-30M | $-24M | $-38M | $-29M | $-13M | $-15M | $-11M | |
| CapEx | $3.0K | · | $21.0K | · | · | $17.0K | $53.0K | $46.0K | |
| Investing Cash Flow | $6M | $-22M | $-21.0K | · | · | $-17.0K | $5M | $-5M | |
| Financing Cash Flow | $52M | $49M | $15M | $19M | $37M | $33M | $17M | $20M | |
| Net Change in Cash | $8M | $-3M | $-9M | $-18M | $7M | $19M | $7M | $4M | |
| Taxes Paid | $0 | $0 | $0 | · | · | · | · | · | |
| Free Cash Flow | · | · | $-24M | · | · | $-13M | $-15M | $-11M |
Rentabilidad 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| ROA | · | -137.3% | -120.8% | · | -75.5% | -48.0% | -81.6% | -87.6% | |
| ROE | · | -152.4% | -2302.3% | · | -105.7% | -46.8% | -125.2% | -84.7% |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | · | 5.5 | 0.8 | · | 9.8 | 12.6 | 6.0 | 4.8 | |
| Quick Ratio | · | 5.1 | 0.7 | · | 9.5 | 12.2 | 5.8 | 4.5 |
Eficiencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | · | · | · | · | · | · | 0.0 | 0.0 | |
| Receivables Turnover | · | · | · | · | · | · | 0.0 | 0.0 |
Valoración (TTM) 9
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | · | · | · | · | · | · | $0 | $0 | |
| Net Income TTM | $-55M | $-40M | $-30M | $-42M | $-33M | $-15M | $-16M | $-13M | |
| Market Cap | · | $122M | $87M | · | $74M | $50M | $313M | $163M | |
| P/E | -4.0 | -2.8 | -2.7 | -0.6 | -1.9 | -1.5 | · | · | |
| P/B | · | 5.8 | -60.2 | · | 2.6 | 1.3 | 17.3 | 10.3 | |
| P / Tangible Book | 13.4 | 6.5 | · | 7.5 | 2.9 | 1.4 | · | · | |
| P / Cash Flow | · | -4.1 | -3.6 | · | -2.5 | -3.7 | -20.5 | -15.3 | |
| P / FCF | · | · | -3.6 | · | · | -3.7 | -20.5 | -15.2 | |
| Earnings Yield | -25.1% | -35.2% | -36.4% | -163.3% | -52.4% | -66.9% | · | · |
Estado de resultados 11
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | · | · | · | $5M | $7M | $7M | · | $8M | $5M | $3M | $4M | $5M | $6M | $10M | $7M | $4M | |
| SG&A Expense | · | · | · | $9M | $6M | $6M | · | $5M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | |
| Operating Expenses | $18M | $10M | $15M | $15M | $13M | $13M | $12M | $12M | $8M | $6M | $7M | $8M | $9M | $13M | $10M | $7M | |
| Interest Expense | · | · | · | · | · | · | · | $366.0K | $804.0K | $813.0K | $781.0K | $712.0K | $573.0K | $481.0K | $404.0K | $357.0K | |
| Interest Income | $1M | $297.0K | $427.0K | $554.0K | $192.0K | $322.0K | $482.0K | $673.0K | $833.0K | $368.0K | $262.0K | $193.0K | $162.0K | $73.0K | $4.0K | $4.0K | |
| Other Non-op | $-5.0K | $-13.0K | $7.0K | $-5.0K | $-59.0K | $21.0K | $-5.0K | $-8.0K | $-2.0K | $-15.0K | $-17.0K | $-6.0K | $-3.0K | $-30.0K | $5.0K | $6.0K | |
| Net Income | $-75M | $-10M | $-15M | $-14M | $-13M | $-13M | $-12M | $-13M | $-8M | $-6M | $-7M | $-8M | $-9M | $-13M | $-10M | $-8M | |
| EPS (Basic) | $-0.80 | $-0.19 | $-0.23 | $-0.28 | $-0.37 | $-0.37 | $-0.37 | $-0.36 | $-0.25 | $-0.26 | $-0.34 | $-0.43 | $-0.50 | $-1.35 | $-1.08 | $-0.80 | |
| EPS (Diluted) | $-0.80 | $-0.19 | $-0.23 | $-0.28 | $-0.37 | $-0.37 | $-0.37 | $-0.36 | $-0.25 | $-0.26 | $-0.34 | $-0.43 | $-0.50 | $-1.35 | $-1.08 | $-0.80 | |
| Shares (Basic) | 93,510,544 | 53,381,989 | -76,793,154 | 51,017,662 | 34,685,072 | 34,685,072 | -61,650,747 | 34,355,050 | 34,318,709 | 25,048,134 | 21,127,281 | 19,048,627 | 17,917,769 | 9,693,788 | 9,647,726 | 9,458,745 | |
| Shares (Diluted) | 93,510,544 | 53,381,989 | -76,793,154 | 51,017,662 | 34,685,072 | 34,685,072 | -61,650,747 | 34,355,050 | 34,318,709 | 25,048,134 | 21,127,281 | 19,048,627 | 17,917,769 | 9,693,788 | 9,647,726 | 9,458,745 |
Balance general 21
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $48M | $28M | $21M | $32M | $52M | $13M | $13M | $10M | $15M | $66M | $20M | $25M | $17M | $18M | $29M | $36M | |
| Short-term Investments | $139M | $1M | $15M | $16M | $4M | $10M | $22M | $33M | $47M | · | · | · | · | · | · | · | |
| Prepaid Expense | · | · | · | $2M | $2M | $2M | · | $3M | $1M | $1M | $2M | $958.0K | $2M | $3M | $1M | $1M | |
| Current Assets | $188M | $31M | $40M | $50M | $57M | $25M | $36M | $46M | $63M | $68M | $22M | $26M | $18M | $21M | $31M | $38M | |
| PP&E (Net) | · | · | $3.0K | · | · | · | $8.0K | · | · | · | · | · | · | · | · | · | |
| PP&E (Gross) | · | · | $256.0K | · | · | · | $256.0K | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $253.0K | · | · | · | $248.0K | · | · | · | · | · | · | · | · | · | |
| Goodwill | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | |
| Intangibles | $640.0K | $696.0K | $751.0K | $807.0K | $863.0K | $918.0K | $974.0K | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $2M | $2M | |
| Total Assets | $190M | $33M | $42M | $52M | $59M | $27M | $39M | $48M | $65M | $70M | $24M | $29M | $21M | $24M | $34M | $41M | |
| Accounts Payable | · | · | · | $2M | $1M | $2M | · | $1M | $550.0K | $373.0K | $638.0K | $361.0K | $1M | $412.0K | $656.0K | $418.0K | |
| Accrued Liabilities | $200.0K | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Current Liabilities | $198M | $12M | $9M | $10M | $9M | $7M | $7M | $7M | $14M | $21M | $4M | $3M | $20M | $7M | $5M | $4M | |
| Capital Leases | · | · | $5.0K | $21.0K | $37.0K | $52.0K | $66.0K | · | · | · | $22.0K | $38.0K | $54.0K | · | · | · | |
| Total Liabilities | $205M | $22M | $20M | $18M | $17M | $17M | $18M | $17M | $23M | $21M | $20M | $19M | $20M | $23M | $21M | $19M | |
| Common Stock | $170.0K | $121.0K | $121.0K | $121.0K | $118.0K | $103.0K | $103.0K | $103.0K | $103.0K | $103.0K | $90.0K | $90.0K | $87.0K | $79.0K | $79.0K | $79.0K | |
| Retained Earnings | $-345M | $-270M | $-260M | $-246M | $-231M | $-218M | $-206M | $-193M | $-181M | $-172M | $-160M | $-153M | $-145M | $-125M | $-112M | $-101M | |
| AOCI | $-88.0K | $2.0K | $10.0K | $9.0K | $3.0K | $6.0K | $31.0K | $75.0K | $-7.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Stockholders' Equity | $-15M | $11M | $22M | $34M | $42M | $10M | $21M | $31M | $42M | $49M | $4M | $10M | $443.0K | $1M | $13M | $21M | |
| Liabilities + Equity | $190M | $33M | $42M | $52M | $59M | $27M | $39M | $48M | $65M | $70M | $24M | $29M | $21M | $24M | $34M | $41M | |
| Shares Outstanding | 102,717,200 | 53,240,988 | 53,233,988 | 52,812,488 | 49,685,072 | 34,685,072 | 34,685,072 | 34,389,946 | 34,341,303 | 34,251,911 | 21,165,760 | 21,105,760 | 17,930,362 | 9,710,747 | 9,681,855 | 9,473,577 |
Flujo de Efectivo 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $58.0K | $57.0K | $57.0K | $54.0K | $55.0K | $62.0K | $58.0K | $57.0K | $57.0K | $57.0K | $58.0K | $55.0K | $58.0K | $55.0K | $56.0K | $60.0K | |
| Stock-based Comp | $7M | $-685.0K | $1M | $2M | $3M | $2M | $1M | $1M | $1M | $1M | $1M | $1M | $1M | $829.0K | $840.0K | $823.0K | |
| Amort. of Intangibles | · | $100.0K | $-100.0K | $100.0K | $100.0K | $100.0K | $-100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | $100.0K | |
| Operating Cash Flow | $-11M | $-7M | $-18M | $-11M | $-9M | $-11M | $-9M | $-10M | $-5M | $-5M | $-5M | $-7M | $-8M | $-11M | $-8M | $-7M | |
| Investing Cash Flow | $-138M | $14M | $709.0K | $-13M | $7M | $11M | $12M | $13M | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $168M | $21.0K | $6M | $4M | · | · | $682.0K | $-8M | $-153.0K | $56M | $0 | $15M | $47.0K | $146.0K | $1M | $95.0K | |
| Net Change in Cash | $20M | $7M | $-11M | $-20M | $39M | $263.0K | $3M | $-5M | $-52M | $51M | $-5M | $9M | $-8M | $-11M | $-7M | $-7M |
Rentabilidad 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -60.0% | -33.6% | · | -28.9% | -20.6% | -26.3% | · | -34.6% | -18.1% | -14.3% | -29.6% | -26.2% | -29.3% | -42.5% | -26.3% | -20.4% | |
| ROE | -554.0% | -97.0% | · | -44.4% | -30.3% | -43.0% | · | -70.7% | -32.6% | -26.0% | -279.7% | -72.1% | -82.2% | -73.2% | -38.8% | -29.4% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 1.0 | 2.6 | · | 5.1 | 6.6 | 3.5 | · | 6.8 | 4.6 | 3.3 | 5.4 | 7.7 | 0.9 | 3.0 | 5.8 | 9.4 | |
| Quick Ratio | 0.9 | 2.5 | · | 4.9 | 6.5 | 3.3 | · | 6.4 | 4.5 | 3.2 | 4.9 | 7.3 | 0.8 | 2.6 | 5.5 | 9.1 |
Valoración (TTM) 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-112M | $-50M | · | $-52M | $-47M | $-40M | · | $-35M | $-30M | $-31M | $-37M | $-41M | $-40M | $-38M | $-32M | $-33M | |
| Market Cap | $671M | $157M | · | $166M | $112M | $93M | · | $163M | $161M | $156M | $91M | $110M | $122M | $32M | $47M | $72M | |
| P/E | -4.0 | -2.4 | · | -2.3 | -1.7 | -2.2 | · | -3.9 | -3.7 | -3.0 | -1.6 | -1.5 | -1.8 | -0.8 | -1.2 | · | |
| P/B | -45.7 | 14.7 | · | 4.9 | 2.7 | 9.0 | · | 5.2 | 3.8 | 3.2 | 22.5 | 11.3 | 275.2 | 30.7 | 3.6 | 3.3 | |
| P / Tangible Book | · | 17.5 | · | 5.2 | 2.8 | 11.1 | · | 5.6 | 4.0 | 3.3 | 51.9 | 14.9 | · | · | 4.5 | 3.8 | |
| P / Cash Flow | · | -22.6 | · | · | · | -8.4 | · | · | · | -29.5 | · | · | -14.7 | · | · | -10.6 | |
| Earnings Yield | -25.1% | -41.2% | · | -43.8% | -59.7% | -46.4% | · | -25.5% | -27.2% | -33.6% | -60.9% | -64.7% | -54.9% | -119.4% | -84.4% | · |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-55M | $-40M | $-30M | $-42M | $-33M |
| EPS Diluido | $-1.25 | $-1.24 | $-1.50 | $-4.00 | $-4.08 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | — | 5.5 | 0.8 | — | 9.8 |
| Ratio Rápido | — | 5.1 | 0.7 | — | 9.5 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | — | — | $-24M | — | — |
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Propietarios institucionales (13F) 123 declarantes · $477.1M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 51 (+34 vs trimestre anterior) | 17 (+8 vs trimestre anterior) | 37 (+16 vs trimestre anterior) | 14 (-8 vs trimestre anterior) | +55.5M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $49 724 879 | 7 614 836 | 10,42% | Acciones |
| TPG GP A, LLC | $44 910 597 | 6 877 580 | 9,41% | Acciones |
| venBio Partners LLC | $38 623 122 | 5 914 720 | 8,10% | Acciones |
| Logos Global Management LP | $35 425 250 | 5 425 000 | 7,43% | Acciones |
| FRANKLIN RESOURCES INC | $32 344 527 | 4 953 220 | 6,78% | Acciones |
| Paradigm Biocapital Advisors LP | $32 335 620 | 4 951 856 | 6,78% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $27 039 502 | 4 140 812 | 5,67% | Acciones |
| Propel Bio Management, LLC | $26 342 138 | 4 034 018 | 5,52% | Acciones |
| STATE STREET CORP | $19 234 285 | 2 945 526 | 4,03% | Acciones |
| Venrock Adviser, LLC | $17 964 239 | 2 751 032 | 3,77% | Acciones |
| Vivo Capital, LLC | $17 964 239 | 2 751 032 | 3,77% | Acciones |
| EVENTIDE ASSET MANAGEMENT, LLC | $14 496 600 | 2 220 000 | 3,04% | Acciones |
| Alyeska Investment Group, L.P. | $12 574 965 | 1 925 722 | 2,64% | Acciones |
| MARSHALL WACE, LLP | $11 778 781 | 1 803 795 | 2,47% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $11 492 229 | 1 759 568 | 2,41% | Acciones |
| Simplify Asset Management Inc. | $9 351 646 | 1 432 105 | 1,96% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $9 090 511 | 1 392 115 | 1,91% | Acciones |
| Caption Management, LLC | $7 676 015 | 1 175 500 | 1,61% | Opción de compra |
| LPL Financial LLC | $5 891 725 | 902 255 | 1,23% | Acciones |
| Spruce Street Capital LP | $4 810 240 | 736 637 | 1,01% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $3 877 194 | 593 751 | 0,81% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3 771 075 | 577 500 | 0,79% | Opción de compra |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $3 510 502 | 537 596 | 0,74% | Acciones |
| KVP Capital Advisors, LP | $3 019 178 | 462 355 | 0,63% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $2 880 951 | 441 187 | 0,60% | Acciones |
| RAYMOND JAMES FINANCIAL INC | $2 741 340 | 419 807 | 0,57% | Acciones |
| UBS Group AG | $1 837 555 | 281 402 | 0,39% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 515 861 | 232 138 | 0,32% | Acciones |
| Caption Management, LLC | $1 487 096 | 227 733 | 0,31% | Acciones |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1 483 472 | 227 178 | 0,31% | Acciones |
| JANE STREET GROUP, LLC | $1 331 467 | 203 900 | 0,28% | Opción de compra |
| CITADEL ADVISORS LLC | $1 326 243 | 203 100 | 0,28% | Opción de compra |
| RENAISSANCE TECHNOLOGIES LLC | $1 162 660 | 178 049 | 0,24% | Acciones |
| TWO SIGMA ADVISERS, LP | $1 043 203 | 209 900 | 0,22% | Acciones |
| CITADEL ADVISORS LLC | $804 032 | 123 129 | 0,17% | Acciones |
| CANTOR FITZGERALD, L. P. | $794 250 | 121 631 | 0,17% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $791 534 | 121 215 | 0,17% | Acciones |
| BANK OF AMERICA CORP /DE/ | $758 727 | 116 191 | 0,16% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $677 161 | 103 700 | 0,14% | Opción de venta |
| WELLS FARGO & COMPANY/MN | $650 564 | 99 627 | 0,14% | Acciones |
| Shay Capital LLC | $606 049 | 92 810 | 0,13% | Acciones |
| XTX Topco Ltd | $587 896 | 90 030 | 0,12% | Acciones |
| RHUMBLINE ADVISERS | $568 253 | 87 023 | 0,12% | Acciones |
| Blue Trust, Inc. | $560 849 | 85 888 | 0,12% | Acciones |
| Diametric Capital, LP | $530 098 | 81 179 | 0,11% | Acciones |
| CITIGROUP INC | $454 632 | 69 622 | 0,10% | Acciones |
| MANCHESTER FINANCIAL INC | $438 666 | 67 177 | 0,09% | Acciones |
| MEMBERS WEALTH LLC | $435 962 | 66 763 | 0,09% | Acciones |
| Virtus Investment Advisers, LLC | $387 066 | 59 275 | 0,08% | Acciones |
| ADAR1 Capital Management, LLC | $351 314 | 53 800 | 0,07% | Acciones |
| JANE STREET GROUP, LLC | $329 197 | 50 413 | 0,07% | Acciones |
| MetLife Investment Management, LLC | $300 282 | 45 985 | 0,06% | Acciones |
| OSAIC HOLDINGS, INC. | $281 540 | 43 115 | 0,06% | Acciones |
| WINTON GROUP Ltd | $277 525 | 42 500 | 0,06% | Acciones |
| GOLDMAN SACHS GROUP INC | $267 573 | 40 976 | 0,06% | Acciones |
| Bank of New York Mellon Corp | $261 559 | 40 055 | 0,05% | Acciones |
| Rafferty Asset Management, LLC | $245 012 | 37 521 | 0,05% | Acciones |
| BlackRock, Inc. | $235 015 | 35 990 | 0,05% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $233 062 | 35 691 | 0,05% | Acciones |
| Next Capital Management LLC | $228 517 | 34 995 | 0,05% | Acciones |
| AMERIFLEX GROUP, INC. | $219 395 | 33 598 | 0,05% | Acciones |
| Vanguard Global Advisers, LLC | $211 624 | 32 408 | 0,04% | Acciones |
| Invesco Ltd. | $202 691 | 31 040 | 0,04% | Acciones |
| JPMORGAN CHASE & CO | $201 042 | 32 270 | 0,04% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $198 329 | 30 372 | 0,04% | Acciones |
| Rockefeller Capital Management L.P. | $195 900 | 30 000 | 0,04% | Acciones |
| Jones Hill Capital LP | $174 743 | 26 760 | 0,04% | Acciones |
| BCV Asset Management Inc. | $164 591 | 26 365 | 0,03% | Acciones |
| AXQ CAPITAL, LP | $164 380 | 25 173 | 0,03% | Acciones |
| Nuveen Asset Management, LLC | $164 271 | 46 668 | 0,03% | Acciones |
| Robertson Stephens Wealth Management, LLC | $163 250 | 25 000 | 0,03% | Acciones |
| Keating Financial Advisory Services, Inc. | $162 669 | 24 911 | 0,03% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $149 916 | 22 958 | 0,03% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $143 884 | 48 940 | 0,03% | Acciones |
| Scientech Research LLC | $143 706 | 22 007 | 0,03% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $134 583 | 20 610 | 0,03% | Acciones |
| SEI INVESTMENTS CO | $133 865 | 20 500 | 0,03% | Acciones |
| Nuveen, LLC | $133 865 | 20 500 | 0,03% | Acciones |
| PROFUND ADVISORS LLC | $129 660 | 19 856 | 0,03% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $125 376 | 19 200 | 0,03% | Acciones |
| nVerses Capital, LLC | $118 852 | 18 201 | 0,02% | Acciones |
| VANGUARD GROUP INC | $112 337 | 22 603 | 0,02% | Acciones |
| Cubist Systematic Strategies, LLC | $111 898 | 35 523 | 0,02% | Acciones |
| MAGNOLIA CAPITAL ADVISORS LLC | $98 603 | 15 100 | 0,02% | Acciones |
| VOYA INVESTMENT MANAGEMENT LLC | $96 931 | 14 844 | 0,02% | Acciones |
| SBI Securities Co., Ltd. | $96 912 | 14 841 | 0,02% | Acciones |
| INTECH INVESTMENT MANAGEMENT LLC | $89 696 | 13 736 | 0,02% | Acciones |
| StoneX Group Inc. | $86 507 | 16 342 | 0,02% | Acciones |
| PRUDENTIAL FINANCIAL INC | $85 151 | 13 040 | 0,02% | Acciones |
| Alpine Global Management, LLC | $81 625 | 12 500 | 0,02% | Acciones |
| NORTHERN TRUST CORP | $79 790 | 12 219 | 0,02% | Acciones |
| Windsor Capital Management, LLC | $70 635 | 10 817 | 0,01% | Acciones |
| BARCLAYS PLC | $66 861 | 10 239 | 0,01% | Acciones |
| ProShare Advisors LLC | $66 554 | 10 192 | 0,01% | Acciones |
| Legal & General Group Plc | $49 334 | 7 555 | 0,01% | Acciones |
| Ameritas Investment Partners, Inc. | $46 128 | 7 064 | 0,01% | Acciones |
| FMR LLC | $41 211 | 6 311 | 0,01% | Acciones |
| Russell Investments Group, Ltd. | $40 642 | 6 224 | 0,01% | Acciones |
| Point72 Asia (Singapore) Pte. Ltd. | $23 641 | 7 505 | 0,00% | Acciones |
| Allworth Financial LP | $19 590 | 3 000 | 0,00% | Acciones |
Informantes de la empresa 48 insiders · 17 directivos · 26 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Andrew D. Goldberg | CEO and President | 18 de abril de 2026 A | — | 0 | 0 | $0 |
| John Bencich | CEO | 16 de agosto de 2024 A | 100 636 | 0 | 0 | $0 |
| Mark K Oki | Chief Financial Officer | 28 de enero de 2026 A | 127 940 | 0 | 1 | $-146 175 |
| Michelle Renee Griffin | CFO | 8 de mayo de 2012 A | — | 0 | 0 | $0 |
| Stephen Charles Anderson | CFO and Secretary | 31 de diciembre de 2009 A | 10 000 | 0 | 0 | $0 |
| Alan Fuhrman | Senior Vice President & CFO | 18 de marzo de 2008 A | — | 0 | 0 | $0 |
| Cindy Jacobs | President & CMO | 4 de septiembre de 2025 M | 115 585 | 0 | 1 | $-76 532 |
| Mark Lawrence Rubinstein | Chief Medical Officer | 28 de enero de 2026 A | — | 0 | 0 | $0 |
| Craig Donnelly | Chief Operations Officer | 28 de enero de 2026 A | — | 0 | 0 | $0 |
| Jaime Xinos | Chief Commercial Officer | 28 de enero de 2026 A | 74 432 | 0 | 1 | $-57 766 |
| Jerry Wann | Principal Accounting Officer | 28 de enero de 2026 A | 32 694 | 0 | 1 | $-38 974 |
| Erik Atkisson | Chief Legal Officer | 4 de diciembre de 2025 A | — | 0 | 0 | $0 |
| Anthony Clarke | CSO | 28 de abril de 2022 M | 3 502 | 0 | 0 | $0 |
| Susan D. Wyrick | PAO | 14 de marzo de 2014 A | 1 312 | 0 | 0 | $0 |
| Cameron William Lawrence | Principal Accounting Officer | 8 de mayo de 2012 A | 950 | 0 | 0 | $0 |
| Craig Steven Eudy | Principal Accounting Officer | 29 de diciembre de 2006 A | — | 0 | 0 | $0 |
| Michael B Stewart | Sr. VP & Chief Medical Officer | 16 de diciembre de 2005 A | — | 0 | 0 | $0 |
| Reid Alexander Waldman | Consejero | 27 de julio de 2026 A | — | 0 | 0 | $0 |
| Christopher Nathan Martin | Consejero | 27 de julio de 2026 A | — | 0 | 0 | $0 |
| Thomas Sellig | Consejero | 27 de julio de 2026 A | — | 0 | 0 | $0 |
| Nancy R. Phelan | Consejero | 27 de julio de 2026 A | — | 0 | 0 | $0 |
| Aaron Royston | Consejero | 27 de julio de 2026 A | — | 0 | 0 | $0 |
| Richard Alistair Stewart | Consejero | 27 de julio de 2026 A | 228 875 | 0 | 1 | $-378 143 |
| Jeffrey S Farrow | Consejero | 27 de julio de 2026 A | — | 0 | 0 | $0 |
| Thomas Braxton King | Consejero | 4 de septiembre de 2025 M | 315 142 | 0 | 1 | $-387 407 |
| Kristen B. Slaoui | Consejero | 6 de junio de 2025 A | — | 0 | 0 | $0 |
| Stuart Duty | Consejero | 6 de junio de 2025 A | — | 0 | 0 | $0 |
| Bridget A Martell | Consejero | 6 de junio de 2025 A | — | 0 | 0 | $0 |
| Vaughn B Himes | Consejero | 22 de enero de 2024 A | — | 0 | 0 | $0 |
| Donald Joseph | Consejero | 31 de mayo de 2022 A | — | 0 | 0 | $0 |
| Martin A Mattingly | Consejero | 31 de mayo de 2022 A | 10 500 | 0 | 0 | $0 |
| Jay M Moyes | Consejero | 31 de mayo de 2022 A | — | 0 | 0 | $0 |
| Scott Daniel Cormack | Consejero | 12 de mayo de 2020 A | 14 810 | 0 | 0 | $0 |
| PARKER H STEWART | Consejero | 12 de mayo de 2020 A | 12 500 | 0 | 0 | $0 |
| Neil James Clendeninn | Consejero | 26 de mayo de 2016 A | 22 421 | 0 | 0 | $0 |
| Jack Goldstein | Consejero | 26 de mayo de 2016 A | 17 500 | 0 | 0 | $0 |
| David V Smith | Consejero | 26 de mayo de 2016 A | 9 500 | 0 | 0 | $0 |
| Dwight Winstead | Consejero | 17 de mayo de 2010 M | 0 | 0 | 0 | $0 |
| Patrick Robert Brady | Consejero | 12 de mayo de 2009 A | — | 0 | 0 | $0 |
| Robert E Ivy | Consejero | 18 de mayo de 2007 M | 1 700 | 0 | 0 | $0 |
| George W Dunbar JR | Consejero | 10 de mayo de 2007 A | 3 250 | 0 | 0 | $0 |
| VENTURES WEST CAPITAL LTD | Propietario del 10% | 15 de diciembre de 2008 S | 41 763 | 0 | 0 | $0 |
| SAC CAPITAL ADVISORS LLC | Propietario del 10% | 19 de febrero de 2004 P | 1 419 752 | 0 | 0 | $0 |
| SAC CAPITAL ASSOCIATES LLC | Propietario del 10% | 19 de febrero de 2004 P | 867 376 | 0 | 0 | $0 |
| S A C CAPITAL MANAGEMENT L L C | Propietario del 10% | 19 de febrero de 2004 P | 1 419 752 | 0 | 0 | $0 |
| Steven A. Cohen | Propietario del 10% | 19 de febrero de 2004 P | 1 419 752 | 0 | 0 | $0 |
| Michael A Martino | — | 6 de julio de 2010 M | 11 000 | 0 | 0 | $0 |
| Richard J Klein | — | 29 de diciembre de 2003 A | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 9 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| venBio Global Strategic Fund V, L.P., venBio Global Strategic GP V, LLC | 27 de abril de 2026 | 9,99% | Presentación inicial | Inversión pasiva | SEC |
| TPG GP A, LLC, James G. Coulter, Jon Winkelried | 24 de abril de 2026 | 12,60% | Presentación inicial | — | SEC |
| Dialectic Capital Management, LP, Dialectic Partners, LLC, Dialectic Life Sciences SPV LLC, Dialectic LS Manager LLC, John Fichthorn ×3 presentaciones | 23 de marzo de 2023 | — | Presentación inicial | — | SEC |
| Richard Stewart | 11 de agosto de 2017 | — | Presentación inicial | — | SEC |
| Anthony Clarke | 11 de agosto de 2017 | — | Presentación inicial | — | SEC |
| Working Opportunity Fund (EVCC) Ltd., GrowthWorks Capital Ltd. ×5 presentaciones | 14 de febrero de 2011 | — | Presentación inicial | — | SEC |
| 28 de octubre de 2010 | — | Presentación inicial | — | SEC | |
| Abingworth LLP | 20 de agosto de 2010 | — | Presentación inicial | Inversión pasiva | SEC |
| SCHERING BERLIN VENTURE CORPORATION, SCHERING BERLIN INC., SCHERING INTERNATIONAL HOLDING GmbH, SCHERING AKTIENGESELLSCHAFT | 31 de octubre de 2005 | — | Presentación inicial | Inversión pasiva | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 9 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IWC · iShares Trust | 0,12% | 263 891 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,03% | 713 270 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,03% | 83 121 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 447 963 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,02% | 1 953 101 SH | 8 de agosto de 2026 | Diario |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 957 103 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 31 465 SH | 8 de agosto de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 3 108 369 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 6 512 SH | 8 de agosto de 2026 | Diario |