PEPG PepGen Inc. - Common Stock
PEPG Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
PEPG Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
PEPG Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 7 50,0%
- Compra 5 35,7%
- Mantener 1 7,1%
- Venta 1 7,1%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
8 analistas · 2026-08-19Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.26 | $-0.30 | 0.04% |
| 31 de marzo de 2026 | $-0.26 | $-0.32 | 0.06% |
| 31 de diciembre de 2025 | $-0.27 | $-0.38 | 0.11% |
| 30 de septiembre de 2025 | $-0.52 | $-0.58 | 0.06% |
| 30 de junio de 2025 | $-0.70 | $-0.84 | 0.14% |
| 31 de marzo de 2025 | $-0.92 | $-0.73 | -0.19% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| PEPG | $448M | -3.1 | — | — | -82.0% | — |
| NERV | $174M | -0.1 | — | — | 339.5% | — |
| TNXP | $200M | -1.1 | 29.8% | -946.2% | -60.0% | — |
| WHWK | $114M | -7.3 | -72.5% | -288.3% | -13.4% | — |
| IVVD | $697M | -8.2 | 110.5% | -98.2% | -36.9% | — |
| DTIL | $100M | -1.2 | -50.1% | -133.4% | -72.4% | — |
| KROS | $398M | 8.9 | — | 35.7% | 17.2% | — |
| CRBP | $143M | -1.4 | — | — | -60.8% | — |
| PYXS | $72M | -0.9 | -14.2% | -574.5% | -112.9% | — |
| KRRO | $75M | -0.6 | 181.5% | -1834.5% | -140.8% | — |
| VYGR | $232M | -1.9 | -49.5% | -296.5% | -54.4% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| R&D Expense | $71M | $76M | $68M | $54M | $19M | |
| SG&A Expense | $23M | $21M | $17M | $14M | $8M | |
| Operating Expenses | $94M | $98M | $85M | $68M | $27M | |
| Operating Income | $-94M | $-98M | $-85M | $-68M | $-27M | |
| Interest Income | $4M | $7M | $6M | $3M | · | |
| Other Non-op | $-11.0K | $-1.0K | $-187.0K | $110.0K | $-172.0K | |
| Pretax Income | $-90M | $-91M | $-79M | $-65M | $-27M | |
| Income Tax | $49.0K | $-617.0K | $73.0K | $4M | $0 | |
| Net Income | $-90M | $-90M | $-79M | $-69M | $-27M | |
| EPS (Basic) | $-2.12 | $-2.85 | $-3.30 | $-4.42 | $-30.27 | |
| EPS (Diluted) | $-2.12 | $-2.85 | $-3.30 | $-4.42 | $-30.27 | |
| Shares (Basic) | 42,221,808 | 31,583,073 | 23,796,000 | 15,639,728 | 901,108 | |
| Shares (Diluted) | 42,221,808 | 31,583,073 | 23,796,000 | 15,639,728 | 901,108 | |
| EBITDA | $-92M | $-96M | $-84M | $-68M | · |
Balance general 20
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Cash & Equivalents | $61M | $49M | $81M | $182M | $133M | |
| Short-term Investments | $88M | $71M | $30M | $0 | · | |
| Prepaid Expense | $3M | $4M | $2M | $4M | $2M | |
| Current Assets | $151M | $124M | $113M | $186M | $140M | |
| PP&E (Net) | $2M | $4M | $5M | $3M | $636.0K | |
| PP&E (Gross) | $6M | $7M | $6M | $4M | $1M | |
| Accum. Depreciation | $4M | $3M | $2M | $389.0K | $430.0K | |
| Other Non-current Assets | $372.0K | $426.0K | $442.0K | $1M | $3M | |
| Total Assets | $174M | $151M | $143M | $217M | $144M | |
| Accounts Payable | $822.0K | $2M | $1M | $1M | $3M | |
| Accrued Liabilities | $9M | $12M | $14M | $12M | $7M | |
| Current Liabilities | $13M | $17M | $18M | $19M | $10M | |
| Capital Leases | $14M | $16M | $17M | $19M | · | |
| Total Liabilities | $26M | $32M | $35M | $38M | $11M | |
| Common Stock | $7.0K | $3.0K | $2.0K | $2.0K | · | |
| Retained Earnings | $-361M | $-271M | $-181M | $-103M | $-34M | |
| AOCI | $11.0K | $23.0K | $34.0K | $-81.0K | $17.0K | |
| Stockholders' Equity | $147M | $119M | $108M | $180M | $-32M | |
| Liabilities + Equity | $174M | $151M | $143M | $217M | $144M | |
| Shares Outstanding | 68,874,944 | 32,619,663 | 23,823,241 | 23,713,196 | 963,588 |
Flujo de Efectivo 12
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| D&A | $1M | $2M | $1M | $500.0K | $200.0K | |
| Stock-based Comp | $11M | $11M | $7M | $5M | $2M | |
| Other Non-cash | $-4M | $-5M | $1M | $5M | · | |
| Operating Cash Flow | $-82M | $-82M | $-69M | $-59M | $-23M | |
| CapEx | $264.0K | $497.0K | $3M | $4M | $500.0K | |
| Investing Cash Flow | $-15M | $-38M | $-32M | $-4M | $-500.0K | |
| Stock Issued | · | $10M | · | $114M | · | |
| Net Stock Activity | · | $10M | · | $114M | · | |
| Financing Cash Flow | $108M | $89M | $-189.0K | $112M | $148M | |
| Net Change in Cash | $11M | $-31M | $-101M | $49M | $125M | |
| Taxes Paid | $82.0K | $71.0K | $3M | · | · | |
| Free Cash Flow | $-82M | $-83M | $-72M | $-63M | · |
Rentabilidad 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| ROA | -55.2% | -61.2% | -43.6% | -38.3% | · | |
| ROE | -82.0% | -70.3% | -67.1% | -37.1% | · | |
| ROIC | -63.5% | -81.8% | -78.2% | -40.2% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Current Ratio | 11.9 | 7.4 | 6.4 | 9.9 | · | |
| Quick Ratio | 11.7 | 7.2 | 6.3 | 9.7 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
| Net Income TTM | $-90M | $-90M | $-79M | $-69M | · | |
| Market Cap | $448M | $124M | $162M | $317M | · | |
| P/E | -3.1 | -1.3 | -2.1 | -3.0 | · | |
| P/B | 3.0 | 1.0 | 1.5 | 1.8 | · | |
| P / Tangible Book | 3.0 | 1.0 | 1.5 | 1.8 | · | |
| P / Cash Flow | -5.5 | -1.5 | -2.3 | -5.3 | · | |
| P / FCF | -5.5 | -1.5 | -2.3 | -5.0 | · | |
| Earnings Yield | -32.6% | -75.2% | -48.5% | -33.1% | · |
Estado de resultados 14
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $13M | $13M | $14M | $13M | $18M | $25M | $19M | $18M | $25M | $15M | $16M | $21M | $17M | $14M | $16M | $14M | |
| SG&A Expense | $6M | $6M | $6M | $5M | $6M | $6M | $5M | $5M | $5M | $5M | $5M | $4M | $4M | $4M | $4M | $3M | |
| Operating Expenses | $19M | $19M | $20M | $19M | $24M | $31M | $24M | $23M | $30M | $20M | $21M | $25M | $21M | $18M | $20M | $18M | |
| Operating Income | $-19M | $-19M | $-20M | $-19M | $-24M | $-31M | $-24M | $-23M | $-30M | $-20M | $-21M | $-25M | $-21M | $-18M | $-20M | $-18M | |
| Interest Income | $1M | $1M | $1M | $634.0K | $842.0K | $1M | $1M | $2M | $2M | $2M | $1M | $2M | $2M | $2M | $943.0K | $250.0K | |
| Other Non-op | $50.0K | $-56.0K | $-5.0K | $-6.0K | $3.0K | $-3.0K | $26.0K | $-39.0K | $-31.0K | $43.0K | $43.0K | $-88.0K | $-62.0K | $-80.0K | $4.0K | $76.0K | |
| Pretax Income | $-18M | $-18M | $-18M | $-18M | $-23M | $-30M | $-23M | $-21M | $-28M | $-18M | $-19M | $-23M | $-20M | $-16M | $-19M | $-17M | |
| Income Tax | $16.0K | $15.0K | $49.0K | $0 | $0 | $0 | $-617.0K | $0 | $0 | · | · | · | · | · | · | · | |
| Net Income | $-18M | $-18M | $-18M | $-18M | $-23M | $-30M | $-22M | $-21M | $-28M | $-18M | $-19M | $-23M | $-20M | $-16M | $-19M | $-17M | |
| EPS (Basic) | $-0.26 | $-0.26 | $0.02 | $-0.52 | $-0.70 | $-0.92 | $-0.69 | $-0.66 | $-0.87 | $-0.63 | $-0.81 | $-0.98 | $-0.82 | $-0.69 | $-0.79 | $-1.23 | |
| EPS (Diluted) | $-0.26 | $-0.26 | $0.02 | $-0.52 | $-0.70 | $-0.92 | $-0.69 | $-0.66 | $-0.87 | $-0.63 | $-0.81 | $-0.98 | $-0.82 | $-0.69 | $-0.79 | $-1.23 | |
| Shares (Basic) | 69,202,376 | 69,091,100 | -57,564,434 | 34,362,876 | 32,748,646 | 32,674,720 | -62,124,057 | 32,581,542 | 32,469,187 | 28,656,401 | -47,546,775 | 23,790,430 | 23,790,430 | 23,761,915 | 23,562,395 | 14,090,455 | |
| Shares (Diluted) | 69,202,376 | 69,091,100 | -57,564,434 | 34,362,876 | 32,748,646 | 32,674,720 | -62,124,057 | 32,581,542 | 32,469,187 | 28,656,401 | -47,546,775 | 23,790,430 | 23,790,430 | 23,761,915 | 23,562,395 | 14,090,455 | |
| EBITDA | $-19M | $-19M | · | $-18M | $-24M | $-31M | · | $-23M | $-30M | $-19M | · | $-24M | $-21M | $-18M | $-19M | $-18M |
Balance general 20
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $23M | $42M | $61M | $143M | $35M | $44M | $49M | $42M | $66M | $134M | $81M | $130M | $147M | $165M | $196M | $219M | |
| Short-term Investments | $94M | $90M | $88M | $21M | $40M | $54M | $71M | $97M | $95M | $41M | $30M | · | · | · | · | · | |
| Prepaid Expense | $3M | $2M | $3M | $3M | $3M | $3M | $4M | $4M | $3M | $2M | $2M | $4M | $3M | $3M | $5M | $3M | |
| Current Assets | $120M | $134M | $151M | $166M | $77M | $101M | $124M | $142M | $165M | $178M | $113M | $133M | $150M | $168M | $204M | $226M | |
| PP&E (Net) | $1M | $2M | $2M | $2M | $2M | $4M | $4M | $4M | $4M | $4M | $5M | $5M | $5M | $5M | $3M | $3M | |
| PP&E (Gross) | $6M | $6M | $6M | $6M | $6M | $7M | $7M | $7M | $7M | $6M | $6M | $6M | $6M | $6M | $3M | $3M | |
| Accum. Depreciation | $4M | $4M | $4M | $4M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | $1M | $871.0K | $540.0K | $245.0K | $415.0K | |
| Other Non-current Assets | $265.0K | $389.0K | $372.0K | $372.0K | $426.0K | $426.0K | $426.0K | $426.0K | $2M | $2M | $442.0K | $2M | $2M | $1M | $1M | $1M | |
| Total Assets | $141M | $156M | $174M | $190M | $102M | $127M | $151M | $170M | $194M | $207M | $143M | $164M | $182M | $201M | $208M | $231M | |
| Accounts Payable | $1M | $622.0K | $822.0K | $766.0K | $856.0K | $3M | $2M | $6M | $8M | $1M | $1M | $4M | $2M | $1M | $5M | $5M | |
| Accrued Liabilities | $5M | $5M | $9M | $9M | $12M | $15M | $12M | $8M | $11M | $7M | $14M | $14M | $12M | $13M | $11M | $15M | |
| Current Liabilities | $9M | $9M | $13M | $13M | $16M | $20M | $17M | $17M | $22M | $11M | $18M | $21M | $17M | $18M | $16M | $21M | |
| Capital Leases | $13M | $13M | $14M | $14M | $15M | $15M | $16M | $16M | $16M | $17M | $17M | $17M | $18M | $18M | · | · | |
| Total Liabilities | $22M | $22M | $26M | $27M | $31M | $36M | $32M | $33M | $38M | $28M | $35M | $38M | $35M | $36M | $16M | $21M | |
| Common Stock | $7.0K | $7.0K | $7.0K | $7.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | $2.0K | |
| Retained Earnings | $-397M | $-379M | $-361M | $-343M | $-325M | $-302M | $-271M | $-249M | $-228M | $-200M | $-181M | $-162M | $-139M | $-119M | $-88M | $-69M | |
| AOCI | $-117.0K | $-59.0K | $11.0K | $-25.0K | $-43.0K | $-22.0K | $23.0K | $91.0K | $-75.0K | $-37.0K | $34.0K | $-57.0K | $13.0K | $-28.0K | $-130.0K | $-99.0K | |
| Stockholders' Equity | $120M | $134M | $147M | $163M | $71M | $92M | $119M | $137M | $155M | $179M | $108M | $126M | $147M | $165M | $193M | $210M | |
| Liabilities + Equity | $141M | $156M | $174M | $190M | $102M | $127M | $151M | $170M | $194M | $207M | $143M | $164M | $182M | $201M | $208M | $231M | |
| Shares Outstanding | · | · | 68,874,944 | · | · | · | 32,619,663 | · | · | · | 23,823,241 | · | · | · | · | · |
Flujo de Efectivo 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $300.0K | $300.0K | $400.0K | $300.0K | $300.0K | $400.0K | $300.0K | $400.0K | $400.0K | $400.0K | $400.0K | $300.0K | $300.0K | $200.0K | $100.0K | $100.0K | |
| Stock-based Comp | $3M | $3M | $2M | $2M | $2M | $3M | $3M | $3M | $3M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | |
| Other Non-cash | · | $-4M | · | · | · | $3M | · | · | · | $-7M | · | · | · | $-651.0K | · | · | |
| Operating Cash Flow | $-16M | $-18M | $-16M | $-19M | $-24M | $-23M | $-19M | $-24M | $-16M | $-23M | $-19M | $-16M | $-17M | $-15M | $-21M | $-13M | |
| CapEx | $30.0K | $0 | $-1.0K | $97.0K | $43.0K | $125.0K | $228.0K | $185.0K | $31.0K | $53.0K | $184.0K | $225.0K | $1M | $1M | $430.0K | $609.0K | |
| Investing Cash Flow | $-4M | $-1M | $-66M | $19M | $15M | $17M | $27M | $-133.0K | $-53M | $-11M | $-30M | $-225.0K | $-1M | $-1M | $-430.0K | $-609.0K | |
| Stock Issued | $0 | $2M | · | $0 | $0 | $0 | $0 | $0 | $0 | $10M | · | · | · | · | $0 | · | |
| Net Stock Activity | · | $2M | · | · | · | $0 | · | · | · | $10M | · | · | · | · | · | · | |
| Financing Cash Flow | $-65.0K | $2M | $-171.0K | $108M | $98.0K | $0 | $128.0K | $327.0K | $1M | $87M | $26.0K | $-534.0K | $-19.0K | $130.0K | $-1M | $113M | |
| Net Change in Cash | $-19M | $-18M | $-82M | $108M | $-9M | $-6M | $7M | $-24M | $-68M | $53M | $-49M | $-17M | $-18M | $-16M | $-23M | $100M | |
| Taxes Paid | $49.0K | $0 | $-4.0K | $0 | $0 | $86.0K | $0 | $0 | $71.0K | $0 | · | · | · | · | · | · | |
| Free Cash Flow | · | $-18M | · | · | · | $-23M | · | · | · | $-23M | · | · | · | $-17M | · | · |
Rentabilidad 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -14.6% | -12.5% | · | -10.0% | -15.6% | -18.1% | · | -12.8% | -15.1% | -8.8% | · | -12.5% | -9.5% | -9.8% | -17.8% | -15.0% | |
| ROE | -18.7% | -15.7% | · | -12.0% | -20.4% | -22.3% | · | -16.2% | -18.7% | -10.5% | · | -14.6% | -10.9% | -28.3% | -19.3% | -16.5% | |
| ROIC | -15.9% | -14.1% | · | -11.4% | -33.6% | · | · | · | · | · | · | · | · | · | · | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 13.4 | 15.0 | · | 13.1 | 4.7 | 4.9 | · | 8.5 | 7.5 | 15.8 | · | 6.4 | 8.9 | 9.3 | 13.2 | 11.0 | |
| Quick Ratio | 13.0 | 14.8 | · | 12.9 | 4.6 | 4.8 | · | 8.3 | 7.3 | 15.6 | · | 6.2 | 8.7 | 9.2 | 12.6 | 10.6 |
Valoración (TTM) 3
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-77M | $-89M | · | $-93M | $-103M | $-98M | · | $-91M | $-89M | $-77M | · | $-78M | $-72M | $-70M | $-62M | $-49M | |
| P/E | -1.0 | -0.7 | · | -1.6 | -0.4 | -0.5 | · | -2.7 | -4.8 | -4.7 | · | -1.5 | -2.5 | -0.6 | -0.3 | -0.3 | |
| Earnings Yield | -96.7% | -135.6% | · | -60.6% | -283.8% | -219.2% | · | -36.7% | -20.7% | -21.2% | · | -64.6% | -39.5% | -177.0% | -330.7% | -355.2% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-90M | $-90M | $-79M | $-69M | $-27M |
| EPS Diluido | $-2.12 | $-2.85 | $-3.30 | $-4.42 | $-30.27 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 11.9 | 7.4 | 6.4 | 9.9 | — |
| Ratio Rápido | 11.7 | 7.2 | 6.3 | 9.7 | — |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-82M | $-83M | $-72M | $-63M | — |
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Propietarios institucionales (13F) 81 declarantes · $99.7M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 10 (-18 vs trimestre anterior) | 27 (+9 vs trimestre anterior) | 19 (-8 vs trimestre anterior) | 28 (+1 vs trimestre anterior) | -2.8M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $36 116 181 | 20 064 545 | 36,24% | Acciones |
| VANGUARD GROUP INC | $12 599 545 | 1 935 414 | 12,64% | Acciones |
| Commodore Capital LP | $8 055 000 | 4 475 000 | 8,08% | Acciones |
| VIKING GLOBAL INVESTORS LP | $6 268 381 | 3 482 434 | 6,29% | Acciones |
| Laurion Capital Management LP | $4 951 539 | 2 750 855 | 4,97% | Acciones |
| ADAR1 Capital Management, LLC | $4 663 953 | 2 591 085 | 4,68% | Acciones |
| Vivo Capital, LLC | $4 185 000 | 2 325 000 | 4,20% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $3 484 656 | 1 935 920 | 3,50% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $3 216 177 | 1 786 765 | 3,23% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $2 736 443 | 1 520 246 | 2,75% | Acciones |
| AWM Investment Company, Inc. | $1 080 000 | 600 000 | 1,08% | Acciones |
| MONIMUS CAPITAL MANAGEMENT, LP | $1 057 838 | 587 688 | 1,06% | Acciones |
| Squarepoint Ops LLC | $952 349 | 529 083 | 0,96% | Acciones |
| Creek Drive Management Group LLC | $810 000 | 450 000 | 0,81% | Acciones |
| Ikarian Capital, LLC | $804 897 | 447 165 | 0,81% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $764 626 | 424 484 | 0,77% | Acciones |
| DIADEMA PARTNERS LP | $671 911 | 373 284 | 0,67% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $659 054 | 366 141 | 0,66% | Acciones |
| Rosalind Advisors, Inc. | $630 000 | 350 000 | 0,63% | Acciones |
| Driehaus Capital Management LLC | $503 836 | 279 909 | 0,51% | Acciones |
| Boxer Capital Management, LLC | $491 206 | 272 892 | 0,49% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $470 657 | 261 476 | 0,47% | Acciones |
| XTX Topco Ltd | $441 625 | 245 347 | 0,44% | Acciones |
| STATE STREET CORP | $412 902 | 229 390 | 0,41% | Acciones |
| Artia Global Partners LP | $369 583 | 205 324 | 0,37% | Acciones |
| GOLDMAN SACHS GROUP INC | $302 598 | 168 110 | 0,30% | Acciones |
| JANE STREET GROUP, LLC | $292 891 | 162 717 | 0,29% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $201 728 | 112 071 | 0,20% | Acciones |
| NORTHERN TRUST CORP | $177 728 | 98 738 | 0,18% | Acciones |
| Qube Research & Technologies Ltd | $177 446 | 98 581 | 0,18% | Acciones |
| RBF Capital, LLC | $171 076 | 95 042 | 0,17% | Acciones |
| Persistent Asset Partners Ltd | $171 005 | 95 003 | 0,17% | Acciones |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $168 660 | 93 700 | 0,17% | Acciones |
| Cubist Systematic Strategies, LLC | $141 695 | 30 670 | 0,14% | Acciones |
| TWO SIGMA ADVISERS, LP | $135 447 | 20 806 | 0,14% | Acciones |
| Rangeley Capital, LLC | $126 000 | 70 000 | 0,13% | Acciones |
| Verdad Advisers, LP | $120 384 | 66 880 | 0,12% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $119 282 | 66 268 | 0,12% | Acciones |
| UBS Group AG | $106 331 | 59 073 | 0,11% | Acciones |
| MARSHALL WACE, LLP | $80 418 | 44 677 | 0,08% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $76 682 | 42 601 | 0,08% | Acciones |
| Quadrature Capital Ltd | $73 685 | 40 936 | 0,07% | Acciones |
| Point72 Asset Management, L.P. | $71 496 | 39 720 | 0,07% | Acciones |
| Rathbones Group PLC | $57 605 | 32 003 | 0,06% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $53 528 | 29 738 | 0,05% | Acciones |
| READYSTATE ASSET MANAGEMENT LP | $51 082 | 28 379 | 0,05% | Acciones |
| Bronte Capital Management Pty Ltd. | $31 997 | 17 776 | 0,03% | Acciones |
| Vanguard Global Advisers, LLC | $31 901 | 17 723 | 0,03% | Acciones |
| Vanguard Personalized Indexing Management, LLC | $31 732 | 17 629 | 0,03% | Acciones |
| Point72 Asia (Singapore) Pte. Ltd. | $31 240 | 6 762 | 0,03% | Acciones |
| Nuveen Asset Management, LLC | $27 595 | 7 281 | 0,03% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $23 971 | 13 317 | 0,02% | Acciones |
| CITADEL ADVISORS LLC | $23 580 | 13 100 | 0,02% | Opción de venta |
| Aigen Investment Management, LP | $23 179 | 12 877 | 0,02% | Acciones |
| China Universal Asset Management Co., Ltd. | $19 814 | 11 008 | 0,02% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $19 080 | 10 600 | 0,02% | Opción de venta |
| BlackRock, Inc. | $18 565 | 10 314 | 0,02% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $18 360 | 10 200 | 0,02% | Opción de compra |
| GROUP ONE TRADING LLC | $17 537 | 9 743 | 0,02% | Acciones |
| Tower Research Capital LLC (TRC) | $10 003 | 5 557 | 0,01% | Acciones |
| JPMORGAN CHASE & CO | $8 695 | 4 885 | 0,01% | Acciones |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $8 071 | 4 484 | 0,01% | Acciones |
| BARCLAYS PLC | $7 742 | 4 301 | 0,01% | Acciones |
| Mirae Asset Global Investments Co., Ltd. | $5 569 | 3 094 | 0,01% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $4 855 | 2 697 | 0,00% | Acciones |
| FMR LLC | $2 995 | 1 664 | 0,00% | Acciones |
| CITIGROUP INC | $2 929 | 1 627 | 0,00% | Acciones |
| GF FUND MANAGEMENT CO. LTD. | $2 569 | 1 427 | 0,00% | Acciones |
| CITADEL ADVISORS LLC | $2 293 | 1 274 | 0,00% | Acciones |
| GSA CAPITAL PARTNERS LLP | $1 535 | 852 852 | 0,00% | Acciones |
| Bare Financial Services, Inc | $589 | 327 | 0,00% | Acciones |
| Rialto Wealth Management, LLC | $573 | 318 | 0,00% | Acciones |
| JONES FINANCIAL COMPANIES LLLP | $554 | 326 | 0,00% | Acciones |
| NISA INVESTMENT ADVISORS, LLC | $351 | 195 | 0,00% | Acciones |
| Cornerstone Financial Management LLC | $218 | 121 | 0,00% | Acciones |
| Integrated Wealth Concepts LLC | $108 | 60 | 0,00% | Acciones |
| Caitong International Asset Management Co., Ltd | $23 | 13 | 0,00% | Acciones |
| MORGAN STANLEY | $22 | 12 | 0,00% | Acciones |
| CWM, LLC | $9 | 5 | 0,00% | Acciones |
| ACADIAN ASSET MANAGEMENT LLC | $1 | 869 | 0,00% | Acciones |
| ROYAL BANK OF CANADA | $0 | 61 | 0,00% | Acciones |
Informantes de la empresa 18 insiders · 9 directivos · 9 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| James G Mcarthur | President and CEO | 17 de abril de 2025 P | 113 913 | 0 | 0 | $0 |
| Noel Donnelly | Chief Financial Officer | 3 de marzo de 2025 A | 24 956 | 0 | 0 | $0 |
| Kasra Kasraian | Chief Technical Officer | 21 de mayo de 2026 S | 50 074 | 0 | 1 | $-1 739 |
| Paul Streck | EVP, Head of R&D | 30 de mayo de 2025 P | 27 805 | 0 | 0 | $0 |
| Mary Beth Delena | General Counsel | 3 de marzo de 2025 A | 14 968 | 0 | 0 | $0 |
| Michelle L Mellion | Chief Medical Officer | 25 de julio de 2024 M | 0 | 0 | 0 | $0 |
| Niels Svenstrup | SVP, Chem. Mfg & Controls | 17 de mayo de 2024 S | 0 | 0 | 0 | $0 |
| Jaya Goyal | EVP, Res. & Preclin. Dev. | 24 de marzo de 2023 M | 0 | 0 | 0 | $0 |
| Sonia Bracegirdle | Sr. VP Strategy & Operations | 6 de mayo de 2022 A | — | 0 | 0 | $0 |
| Lisa Wyman | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Howard Mayer | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Joshua Resnick | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Habib J Dable | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Laurie Keating | Consejero | 18 de junio de 2026 A | 4 166 | 0 | 0 | $0 |
| Mitchell H. Finer | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Heidi Henson | Consejero | 18 de junio de 2026 A | — | 0 | 0 | $0 |
| Christopher Ashton | Consejero | 20 de junio de 2024 A | — | 0 | 0 | $0 |
| Oxford Sciences Innovation plc | Propietario del 10% | 10 de mayo de 2022 P | 4 755 388 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 1 tenencia
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×5 presentaciones | 30 de septiembre de 2025 | 29,20% | Enmienda | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 9 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IBRN · iShares Trust | 0,14% | 4 634 SH | 8 de agosto de 2026 | Diario |
| IWC · iShares Trust | 0,02% | 140 776 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,01% | 3 729 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,01% | 463 527 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,01% | 2 541 NS | 31 de mayo de 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,00% | 42 601 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,00% | 17 863 NS | 30 de abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 480 909 SH | 8 de agosto de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 408 449 SH | 8 de agosto de 2026 | Diario |