PTCT PTC Therapeutics, Inc. - Common Stock
$72,62
Precio · Ago 19, 2026
Fundamentales a fecha de Jul 30, 2026
Rango 52S
$48–$91
57% of range
Calificación del Analista
BUY
21 analysts
Precio Objetivo
$98
+35% upside
P/E (TTM)
9.3
ROE
-331.5%
Margen de Beneficio Neto
39.4%
Acerca de PTC Therapeutics, Inc. - Common Stock Descripción general de la empresa de Wikipedia
PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.
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PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.
In September 2009, PTC entered into an agreement with Roche for the development of orally bioavailable small molecules for central nervous system diseases. PTC acquired the Bio-e platform in 2019.
Products
In 2017, PTC acquired Emflaza (deflazacort) from Marathon Pharmaceuticals. PTC also owns Translarna, (Ataluren) marketed for nonsense mutation Duchenne muscular dystrophy. Together, the two products generated revenues of 174 million dollars and 260 million dollars in 2017 and 2018 respectively.
PTC has the commercialization rights for WAYLIVRA (volanesorsen) in Latin America.
In 2018, PTC acquired Agilis Biotherapeutics and a gene therapy candidate, GT-AADC, with its compelling clinical data in treating aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency is a rare CNS disorder arising from reductions in the enzyme AADC that result from mutations in the dopa decarboxylase (DDC) gene. As of 2024, the AAV based treatment for AADC deficiency has been approved by the FDA and commercialized in the United States as Kebilidi. It is the first FDA-approved gene therapy treatment for AADC deficiency. This same product was granted EMA approval for use in the European Union under the name Upstaza.
Pipeline
In 2020, PTC acquired Censa Pharmaceuticals, Inc., a biopharmaceutical company focused on the development of CNSA-001 (sepiapterin), a clinical-stage investigational therapy for orphan metabolic diseases, including phenylketonuria (PKU) and other diseases associated with defects in the tetrahydrobiopterin (BH4) biochemical pathways diagnosed at birth.
In 2020, PTC announced the FDA approval of Evrysdi (risdiplam) for the treatment of spinal muscular atrophy (SMA) in adults and children 2 months and older.
In 2024, Novartis has committed $1 billion upfront in a licensing deal with PTC Therapeutics for an experimental treatment for Huntington’s disease, with the potential for an additional $1.9 billion tied to achieving specific development, regulatory, and commercial milestones. PTC Therapeutics’ therapy, known as PTC518, is an oral medication designed to reduce the production of the mutant protein linked to the genetic mutation responsible for the disease. This mutant protein is believed to contribute to neuronal death, driving disease progression. In June, interim data from a Phase 2 trial indicated that PTC518 successfully lowered levels of the mutant protein in both blood and cerebrospinal fluid.
Fuente: Wikipedia (Inglés), CC BY-SA 4.0 · Ver en Wikipedia ↗
PTCT Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$72.62
Capitalización Bursátil
$5.92B
P/E (TTM)
9.3
BPA (TTM)
$7.78
Ingresos (TTM)
$1.73B
Rendimiento div.
—
ROE
-331.5%
Deuda/Capital
-1.4
Rango 52S
$48 – $91
PTCT Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
$1.73B
2016-12-31
→
2025-12-31
BPA
$7.78
2019-12-31
→
2025-12-31
Flujo de caja libre
$702M
2016-12-31
→
2025-12-31
Márgenes
39.4%
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
PTCT
Mediana de Pares
P/E (TTM)
9.3
37.2
P/S (TTM) (P/V (TTM))
3.4
9.9
P/B (P/C)
-28.8
8.3
EV / EBITDA
4.7
—
Price / FCF (Precio / FCF)
8.4
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
PTCT
Mediana de Pares
Operating Margin (Margen Operativo)
50.1%
—
Net Profit Margin (Margen de Beneficio Neto)
39.4%
-15.1%
ROA
29.7%
-23.3%
ROE
-331.5%
-30.6%
ROIC
1044.7%
—
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
PTCT
Mediana de Pares
Debt / Equity (Deuda / Patrimonio)
-1.4
—
Current Ratio (Ratio corriente)
2.3
6.3
Quick Ratio (Ratio Rápido)
2.2
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
PTCT
Mediana de Pares
Revenue YoY (Ingresos interanuales)
114.5%
—
Revenue CAGR 3Y (Ingresos CAGR 3A)
35.3%
—
Revenue CAGR 5Y (Ingresos CAGR 5A)
35.4%
—
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
PTCT
Mediana de Pares
PTCT Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
21 analistas
- Compra fuerte 6 28,6%
- Compra 11 52,4%
- Mantener 3 14,3%
- Venta 1 4,8%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
14 analistas · 2026-08-13
Mediana
$98.00
Ahora
$72.62
Mín
$70.00
Máx
$130.00
Objetivo mediano
$98.00
+34,9%
Objetivo medio
$97.86
+34,8%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
1.9%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $0.92 | $0.43 | 0.49% |
| 31 de marzo de 2026 | $-0.03 | $-0.48 | 0.45% |
| 31 de diciembre de 2025 | $-1.67 | $0.04 | -1.7% |
| 30 de septiembre de 2025 | $0.20 | $-1.40 | 1.6% |
| 30 de junio de 2025 | $-0.83 | $-1.08 | 0.25% |
| 31 de marzo de 2025 | $10.04 | $-0.22 | 10.3% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| PTCT | $6.19B | 9.8 | 114.5% | 39.4% | -331.5% | — |
| MIRM | $4.10B | -168.1 | 54.7% | -4.5% | -8.2% | — |
| COGT | $5.72B | -16.4 | — | — | -83.1% | — |
| DNTH | $1.78B | -9.8 | -67.3% | -7973.3% | -40.8% | — |
| ERAS | $1.06B | -8.5 | — | — | -35.7% | — |
| CAI | $7.62B | -8.4 | 97.0% | -8.4% | -13.2% | — |
| TVTX | $3.47B | -131.8 | 110.5% | -5.2% | -34.6% | — |
| ACAD | $4.55B | 11.6 | 11.9% | 36.5% | 38.1% | — |
| DYN | $3.23B | -5.6 | — | — | -57.8% | — |
| PBLS | — | — | — | — | — | — |
| CELC | $4.81B | -26.3 | — | — | -244.3% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 15
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $1.73B | $807M | $938M | $699M | $539M | $381M | $307M | $265M | $194M | $83M | $37M | $25M | |
| Cost of Revenue | · | · | · | · | · | · | $12M | $13M | $5M | $0 | $0 | · | |
| R&D Expense | $455M | $534M | $667M | $651M | $541M | $478M | $257M | $172M | $117M | $118M | $122M | $80M | |
| SG&A Expense | $347M | $301M | $333M | $326M | $286M | $245M | $203M | $154M | $121M | $97M | $82M | $45M | |
| Operating Expenses | $864M | $1.11B | $1.38B | $1.15B | $913M | $813M | $548M | $380M | $259M | $215M | $204M | $125M | |
| Operating Income | $867M | $-303M | $-440M | $-447M | $-374M | $-432M | $-241M | $-116M | $-64M | $-132M | $-167M | $-99M | |
| Other Non-op | $-18M | $7M | $10M | $-49M | $-58M | $85M | $14M | $129.0K | $-1M | $-1M | $-465.0K | $-213.0K | |
| Pretax Income | $697M | $-363M | $-696M | $-587M | $-518M | $-403M | $-240M | $-128M | $-78M | $-142M | $-170M | $-98M | |
| Income Tax | $14M | $176.0K | $-70M | $-28M | $6M | $35M | $12M | $-29.0K | $1M | $569.0K | $485.0K | $-5M | |
| Net Income | $683M | $-363M | $-627M | $-559M | $-524M | $-438M | $-252M | $-128M | $-79M | $-142M | $-170M | $-94M | |
| EPS (Basic) | $8.58 | $-4.73 | $-8.37 | $-7.79 | $-7.43 | $-6.64 | $-4.27 | $-2.75 | $-2.02 | · | · | $-2.97 | |
| EPS (Diluted) | $7.78 | $-4.73 | $-8.37 | $-7.79 | $-7.43 | $-6.64 | $-4.27 | · | · | · | · | $-2.97 | |
| Shares (Basic) | 79,534,290 | 76,845,055 | 74,838,292 | 71,728,634 | 70,466,393 | 66,027,908 | 58,863,185 | · | · | · | · | 31,565,310 | |
| Shares (Diluted) | 88,311,494 | 76,845,055 | 74,838,292 | 71,728,634 | 70,466,393 | 66,027,908 | 58,863,185 | · | · | · | · | 31,565,310 | |
| EBITDA | $906M | $-227M | $-203M | · | $-310M | $-388M | $-209M | $-90M | $-47M | $-132M | $-167M | $-99M |
Balance general 27
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $985M | $780M | $594M | $280M | $190M | $209M | $288M | $169M | $112M | $58M | $58M | $50M | |
| Short-term Investments | $961M | $360M | $283M | $131M | $584M | $895M | $399M | $58M | $79M | $173M | $281M | $265M | |
| Receivables | $182M | $159M | $161M | $156M | $110M | $70M | $56M | $68M | $40M | $25M | $11M | $4M | |
| Inventory | $80M | $23M | $31M | $22M | $16M | $19M | $19M | $16M | $11M | $0 | · | · | |
| Prepaid Expense | $67M | $44M | $150M | $106M | $55M | $39M | $18M | $9M | $7M | $5M | $6M | $4M | |
| Current Assets | $2.27B | $1.37B | $1.22B | $694M | $954M | $1.23B | $779M | $321M | $249M | $261M | $356M | $324M | |
| PP&E (Net) | $55M | $61M | $87M | $73M | $53M | $34M | $22M | $13M | $8M | $7M | $9M | $9M | |
| PP&E (Gross) | $102M | $94M | $138M | $110M | $80M | $52M | $33M | $20M | $41M | $38M | $37M | $34M | |
| Accum. Depreciation | $47M | $33M | $51M | $37M | $27M | $18M | $12M | $7M | $33M | $31M | $28M | $25M | |
| Goodwill | $82M | $82M | $82M | $82M | $82M | $82M | $82M | $82M | $0 | · | · | · | |
| Intangibles | $389M | $119M | $379M | $706M | $725M | $715M | $710M | $701M | $133M | $0 | · | · | |
| Total Assets | $2.90B | $1.71B | $1.90B | $1.71B | $1.94B | $2.21B | $1.62B | $1.12B | $392M | $269M | $365M | $333M | |
| Accounts Payable | $45M | $17M | $6M | $27M | $23M | $19M | $10M | $6M | $15M | $6M | $6M | $4M | |
| Current Liabilities | $968M | $581M | $603M | $406M | $509M | $277M | $236M | $167M | $82M | $50M | $45M | $32M | |
| Capital Leases | $94M | $75M | $98M | $101M | $74M | $79M | $9M | · | · | · | · | · | |
| Deferred Tax | · | · | $56M | $103M | $137M | $137M | $131M | $122M | $0 | · | · | · | |
| Other Non-current Liabilities | $14M | $21M | $141.0K | $3M | · | $1M | $141.0K | $58.0K | $243.0K | $335.0K | $2M | $2M | |
| Total Liabilities | $3.10B | $2.80B | $2.71B | $2.05B | $1.94B | $1.73B | $1.03B | $768M | $235M | $150M | $139M | $35M | |
| Long-term Debt | · | · | · | · | $431M | · | $314M | $153M | $145M | · | · | · | |
| Total Debt | $287M | $285M | $284M | · | $431M | $309M | $314M | $153M | $145M | $98M | $95M | · | |
| Common Stock | $80.0K | $77.0K | $75.0K | $72.0K | $71.0K | $70.0K | $62.0K | $51.0K | $42.0K | $34.0K | $34.0K | $33.0K | |
| Paid-in Capital | $2.75B | $2.57B | $2.47B | $2.31B | $2.12B | $2.17B | $1.80B | $1.29B | $967M | $856M | $820M | $722M | |
| Retained Earnings | $-2.96B | $-3.65B | $-3.28B | $-2.66B | $-2.10B | $-1.63B | $-1.19B | $-939M | $-814M | $-735M | $-593M | $-423M | |
| AOCI | $11M | $-26M | $-1M | $5M | $-24M | $-61M | $-11M | $1M | $4M | $-1M | $-1M | $-737.0K | |
| Stockholders' Equity | $-205M | $-1.10B | $-819M | $-347M | $1M | $482M | $594M | $351M | $156M | $120M | $226M | $298M | |
| Liabilities + Equity | $2.90B | $1.71B | $1.90B | $1.71B | $1.94B | $2.21B | $1.62B | $1.12B | $392M | $269M | $365M | $333M | |
| Shares Outstanding | 81,474,366 | 77,704,188 | 75,708,889 | 73,104,692 | 70,828,226 | 69,718,096 | 61,935,870 | 50,606,147 | 41,612,395 | 34,169,410 | 33,916,559 | 32,898,392 |
Flujo de Efectivo 16
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $39M | $76M | $237M | $129M | $64M | $43M | $32M | $26M | $18M | $3M | $3M | · | |
| Stock-based Comp | $75M | $75M | $102M | $110M | $104M | $70M | $42M | $33M | $31M | $35M | $34M | $19M | |
| Deferred Tax | $-3.0K | $-56M | $-47M | $-34M | $377.0K | $6M | $9M | $0 | $199.0K | $-199.0K | $0 | $0 | |
| Amort. of Intangibles | $25M | $61M | $223M | $117M | $55M | $37M | $28M | $23M | $15M | $0 | $0 | · | |
| Restructuring | · | · | · | · | · | · | · | · | $0 | · | · | · | |
| Other Non-cash | $-85M | $161M | $177M | · | $105M | $124M | $70M | $41M | $20M | · | · | · | |
| Operating Cash Flow | $711M | $-108M | $-158M | $-357M | $-251M | $-194M | $-99M | $-28M | $-10M | $-104M | $-124M | $-57M | |
| CapEx | $9M | $7M | $28M | $32M | $28M | $18M | $14M | $7M | $3M | $2M | $3M | $5M | |
| Investing Cash Flow | $-862M | $44M | $-177M | $290M | $219M | $-562M | $-387M | $-43M | $13M | $104M | $-21M | $-145M | |
| Net Debt Issued | · | · | · | · | · | · | · | · | · | $0 | · | $-49.0K | |
| Stock Issued | · | · | · | · | · | $28M | $324M | $118M | $0 | $0 | $0 | $236M | |
| Net Stock Activity | · | · | · | · | · | $28M | $324M | $118M | · | $0 | · | $236M | |
| Financing Cash Flow | $331M | $256M | $646M | $168M | $21M | $669M | $613M | $132M | $44M | $968.0K | $154M | $237M | |
| Net Change in Cash | $203M | $185M | $314M | $99M | $-19M | $-79M | $126M | $58M | $53M | $299.0K | $8M | $34M | |
| Taxes Paid | $37M | $18M | $14M | $5M | $8M | $26M | $2M | $2M | $1M | $943.0K | $111.0K | $0 | |
| Free Cash Flow | $702M | $-114M | $-187M | · | $-280M | $-212M | $-112M | $-35M | $-13M | $-105M | $-127M | $-62M |
Rentabilidad 7
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | 50.1% | -37.5% | -46.9% | · | -69.5% | -113.4% | -78.6% | -43.7% | -33.1% | -159.7% | -454.6% | -393.8% | |
| Net Margin | 39.4% | -45.0% | -66.8% | · | -97.3% | -115.1% | -82.0% | -48.4% | -40.6% | -171.8% | -463.6% | -371.4% | |
| Pretax Margin | 40.2% | -45.0% | -74.2% | · | -96.2% | -105.8% | -78.2% | -48.4% | -40.0% | -171.1% | -462.3% | -390.0% | |
| EBITDA Margin | 52.3% | -28.1% | -21.6% | · | -57.6% | -102.0% | -68.1% | -33.8% | -24.0% | -159.7% | -454.6% | -393.8% | |
| ROA | 29.7% | -20.2% | -34.8% | · | -25.3% | -22.9% | -18.3% | -17.0% | -23.9% | -44.8% | -48.6% | -38.6% | |
| ROE | -331.5% | 33.8% | 84.1% | · | -985.1% | -88.3% | -40.0% | -34.8% | -57.2% | -82.2% | -65.0% | -43.1% | |
| ROIC | 1044.7% | 37.2% | 74.0% | · | -87.4% | -59.4% | -27.8% | -23.0% | -21.7% | -60.9% | -52.3% | -31.7% |
Liquidez y Solvencia 4
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.3 | 2.4 | 2.0 | · | 1.9 | 4.4 | 3.3 | 1.9 | 3.0 | 5.3 | 7.8 | 10.0 | |
| Quick Ratio | 2.2 | 2.2 | 1.7 | · | 1.7 | 4.2 | 3.1 | 1.8 | 2.8 | 5.2 | 7.7 | 9.8 | |
| Debt / Equity | -1.4 | -0.3 | -0.3 | · | 300.0 | 0.6 | 0.5 | 0.4 | 0.9 | 0.8 | 0.4 | · | |
| LT Debt / Equity | · | -0.3 | -0.3 | · | 196.0 | 0.6 | 0.5 | 0.4 | 0.9 | 0.8 | 0.4 | · |
Eficiencia 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.8 | 0.4 | 0.5 | · | 0.3 | 0.2 | 0.2 | 0.4 | 0.6 | 0.3 | 0.1 | 0.1 | |
| Inventory Turnover | · | · | · | · | · | · | 0.7 | · | 0.9 | · | · | · | |
| Receivables Turnover | 10.2 | 5.1 | 5.9 | · | 6.0 | 6.1 | 5.0 | 4.9 | 6.0 | 4.6 | 4.7 | 9.3 |
Tasas de Crecimiento 3
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY | 114.5% | -14.0% | 34.2% | 29.8% | 41.4% | · | · | · | · | · | · | · | |
| Revenue CAGR 3Y | 35.3% | 14.4% | 35.0% | · | · | · | · | · | · | · | · | · | |
| Revenue CAGR 5Y | 35.4% | · | · | · | · | · | · | · | · | · | · | · |
Valoración (TTM) 13
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $1.73B | $807M | $938M | $699M | $539M | $381M | $307M | $265M | $194M | $83M | $37M | $25M | |
| Net Income TTM | $683M | $-363M | $-627M | $-559M | $-524M | $-438M | $-252M | $-128M | $-79M | $-142M | $-170M | $-94M | |
| Market Cap | $6.19B | $3.51B | $2.09B | · | $2.82B | $4.25B | $2.97B | $1.74B | $694M | $373M | $1.10B | $1.70B | |
| Enterprise Value | $4.53B | $2.65B | $1.49B | · | $2.48B | $3.46B | $2.60B | $1.66B | $648M | $239M | $855M | · | |
| P/E | 9.8 | -9.5 | -3.3 | -4.9 | -5.4 | -9.2 | -11.2 | -10.7 | -5.2 | -3.4 | -10.1 | -17.4 | |
| P/S | 3.6 | 4.3 | 2.2 | · | 5.2 | 11.2 | 9.7 | 6.6 | 3.6 | 4.5 | 29.9 | 67.5 | |
| P/B | -30.1 | -3.2 | -2.5 | · | 1961.8 | 8.8 | 5.0 | 5.0 | 4.4 | 3.1 | 4.9 | 5.7 | |
| P / Cash Flow | 8.7 | -32.6 | -13.2 | · | -11.2 | -21.9 | -30.2 | -62.8 | -69.0 | -3.6 | -8.8 | -29.7 | |
| P / FCF | 8.8 | -30.7 | -11.2 | · | -10.1 | -20.1 | -26.5 | -50.0 | -52.7 | -3.5 | -8.6 | -27.5 | |
| EV / EBITDA | 5.0 | -11.7 | -7.4 | · | -8.0 | -8.9 | -12.5 | -18.6 | -13.9 | -1.8 | -5.1 | · | |
| EV / FCF | 6.5 | -23.2 | -8.0 | · | -8.9 | -16.3 | -23.2 | -47.9 | -49.2 | -2.3 | -6.7 | · | |
| EV / Revenue | 2.6 | 3.3 | 1.6 | · | 4.6 | 9.1 | 8.5 | 6.3 | 3.3 | 2.9 | 23.2 | · | |
| Earnings Yield | 10.2% | -10.5% | -30.4% | -20.4% | -18.6% | -10.9% | -8.9% | -9.3% | -19.2% | -29.4% | -9.9% | -5.7% |
Estado de resultados 14
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $361M | $273M | $165M | $211M | $179M | $1.18B | $213M | $197M | $187M | $210M | $307M | $197M | $214M | $220M | $167M | $217M | |
| R&D Expense | $99M | $101M | $133M | $100M | $113M | $109M | $125M | $161M | $132M | $116M | $121M | $164M | $186M | $195M | $189M | $165M | |
| SG&A Expense | $81M | $86M | $97M | $84M | $85M | $81M | $85M | $73M | $70M | $73M | $76M | $81M | $88M | $87M | $93M | $80M | |
| Operating Expenses | $212M | $228M | $236M | $208M | $214M | $206M | $376M | $251M | $227M | $256M | $301M | $315M | $423M | $338M | $368M | $285M | |
| Operating Income | $149M | $45M | $-71M | $3M | $-35M | $970M | $-162M | $-55M | $-40M | $-45M | $6M | $-118M | $-210M | $-118M | $-200M | $-68M | |
| Other Non-op | $-3M | $2M | $-13M | $7M | $-6M | $-6M | $9M | $-2M | $-2M | $2M | $19M | $-20M | $1M | $10M | $35M | $-38M | |
| Pretax Income | $98M | $-2M | $-139M | $-23M | $-71M | $930M | $-95M | $-98M | $-86M | $-85M | $-157M | $-167M | $-237M | $-135M | $-190M | $-127M | |
| Income Tax | $14M | $347.0K | $-4M | $-39M | $-6M | $63M | $-29M | $9M | $13M | $7M | $-1M | $-34M | $-39M | $4M | $-19M | $-18M | |
| Net Income | $83M | $-3M | $-135M | $16M | $-65M | $867M | $-66M | $-107M | $-99M | $-92M | $-156M | $-133M | $-199M | $-139M | $-171M | $-109M | |
| EPS (Basic) | $1.01 | $-0.03 | $-1.88 | $0.20 | $-0.83 | $11.09 | $-0.85 | $-1.39 | $-1.29 | $-1.20 | $-2.07 | $-1.76 | $-2.66 | $-1.88 | $-2.35 | $-1.53 | |
| EPS (Diluted) | $0.92 | $-0.03 | $-1.63 | $0.20 | $-0.83 | $10.04 | $-0.85 | $-1.39 | $-1.29 | $-1.20 | $-2.07 | $-1.76 | $-2.66 | $-1.88 | $-2.35 | $-1.53 | |
| Shares (Basic) | 83,006,808 | 82,521,023 | -155,203,905 | 78,471,119 | 78,151,240 | 78,115,836 | -153,301,665 | 76,925,523 | 76,725,070 | 76,496,127 | -148,999,422 | 75,377,997 | 74,730,433 | 73,729,284 | -142,514,082 | 71,654,671 | |
| Shares (Diluted) | 92,020,009 | 82,521,023 | -163,341,037 | 87,115,369 | 78,151,240 | 86,385,922 | -153,301,665 | 76,925,523 | 76,725,070 | 76,496,127 | -148,999,422 | 75,377,997 | 74,730,433 | 73,729,284 | -142,514,082 | 71,654,671 | |
| EBITDA | $149M | $60M | · | $3M | $-35M | $977M | · | $-55M | $-40M | $10M | · | $-118M | $-210M | $-75M | · | $-68M |
Balance general 27
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $1.05B | $834M | $985M | $673M | $1.02B | $1.48B | $780M | $526M | $655M | $548M | · | $165M | $208M | $167M | · | $104M | |
| Short-term Investments | $1.18B | $1.06B | $961M | $1.02B | $972M | $547M | $360M | $487M | $439M | $336M | · | $130M | $130M | $119M | · | $184M | |
| Receivables | $239M | $220M | $182M | $203M | $196M | $210M | $159M | $200M | $187M | $198M | · | $166M | $178M | $202M | · | $124M | |
| Inventory | $91M | $76M | $80M | $53M | $34M | $22M | $23M | $36M | $32M | $30M | · | $36M | $32M | $27M | · | $15M | |
| Prepaid Expense | $58M | $66M | $67M | $64M | $54M | $57M | $44M | $33M | $46M | $56M | · | $44M | $42M | $99M | · | $90M | |
| Current Assets | $2.62B | $2.25B | $2.27B | $2.01B | $2.27B | $2.32B | $1.37B | $1.28B | $1.36B | $1.17B | · | $540M | $590M | $613M | · | $517M | |
| PP&E (Net) | $51M | $53M | $55M | $57M | $57M | $59M | $61M | $63M | $66M | $93M | · | $85M | $82M | $79M | · | $67M | |
| PP&E (Gross) | · | · | $102M | · | · | · | $94M | · | · | · | · | · | · | · | · | · | |
| Accum. Depreciation | · | · | $47M | · | · | · | $33M | · | · | · | · | · | · | · | · | · | |
| Goodwill | $82M | $82M | $82M | $82M | $82M | $82M | $82M | $82M | $82M | $82M | · | $82M | $82M | $82M | · | $82M | |
| Intangibles | $403M | $381M | $389M | $396M | $144M | $118M | $119M | $330M | $330M | $330M | · | $423M | $452M | $686M | · | $750M | |
| Total Assets | $3.25B | $2.87B | $2.90B | $2.64B | $2.63B | $2.66B | $1.71B | $1.84B | $1.92B | $1.79B | · | $1.26B | $1.34B | $1.61B | · | $1.58B | |
| Accounts Payable | $40M | $25M | $45M | $37M | $27M | $15M | $17M | $13M | $24M | $27M | · | $19M | $26M | $26M | · | $21M | |
| Current Liabilities | $771M | $924M | $968M | $866M | $628M | $595M | $581M | $611M | $610M | $575M | · | $492M | $476M | $442M | · | $420M | |
| Capital Leases | $88M | $90M | $94M | $95M | $71M | $74M | $75M | $83M | $79M | $105M | · | $100M | $100M | $100M | · | $102M | |
| Deferred Tax | · | · | · | · | · | · | · | $56M | $56M | $56M | · | $52M | $52M | $103M | · | $137M | |
| Other Non-current Liabilities | $15M | $14M | $14M | $3M | $8M | $22M | $21M | $77.0K | $141.0K | $141.0K | · | $141.0K | $141.0K | $141.0K | · | $5M | |
| Total Liabilities | $3.42B | $3.05B | $3.10B | $2.80B | $2.84B | $2.84B | $2.80B | $2.90B | $2.90B | $2.68B | · | $1.93B | $1.92B | $2.07B | · | $1.80B | |
| Long-term Debt | $591M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Total Debt | $591M | $287M | · | $286M | $286M | $286M | · | $285M | $285M | $285M | · | $573M | $573M | $572M | · | $283M | |
| Common Stock | $82.0K | $81.0K | $80.0K | $79.0K | $78.0K | $78.0K | $77.0K | $76.0K | $76.0K | $76.0K | · | $75.0K | $75.0K | $73.0K | · | $71.0K | |
| Paid-in Capital | $2.71B | $2.78B | $2.75B | $2.67B | $2.63B | $2.61B | $2.57B | $2.53B | $2.51B | $2.49B | · | $2.45B | $2.42B | $2.34B | · | $2.22B | |
| Retained Earnings | $-2.88B | $-2.97B | $-2.96B | $-2.83B | $-2.85B | $-2.78B | $-3.65B | $-3.58B | $-3.47B | $-3.38B | · | $-3.13B | $-2.99B | $-2.80B | · | $-2.49B | |
| AOCI | $6M | $8M | $11M | $6M | $7M | $-14M | $-26M | $-4M | $-16M | $-6M | · | $10M | $-1M | $-2M | · | $36M | |
| Stockholders' Equity | $-165M | $-180M | $-205M | $-156M | $-207M | $-186M | $-1.10B | $-1.05B | $-980M | $-894M | $-819M | $-671M | $-579M | $-458M | $-347M | $-227M | |
| Liabilities + Equity | $3.25B | $2.87B | $2.90B | $2.64B | $2.63B | $2.66B | $1.71B | $1.84B | $1.92B | $1.79B | · | $1.26B | $1.34B | $1.61B | · | $1.58B | |
| Shares Outstanding | 83,327,286 | 82,882,024 | 81,474,366 | 79,931,766 | 79,378,145 | 79,225,276 | 77,704,188 | 76,952,124 | 76,900,123 | 76,653,960 | · | 75,459,022 | 75,318,233 | 74,012,034 | · | 71,854,892 |
Flujo de Efectivo 13
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $16M | $15M | $13M | $11M | $8M | $7M | $7M | $6M | $7M | $55M | $81M | $62M | $51M | $43M | $39M | $34M | |
| Stock-based Comp | $23M | $23M | $19M | $19M | $19M | $18M | $17M | $20M | $19M | $18M | $17M | $27M | $29M | $29M | $27M | $29M | |
| Deferred Tax | · | $-10.0K | $1.0K | · | · | $2.0K | $-56M | $-3.0K | $2.0K | $-1.0K | $4M | $-2.0K | $-51M | $-4.0K | · | · | |
| Amort. of Intangibles | $12M | $12M | $9M | $8M | $4M | $4M | $3M | $3M | $3M | $52M | $77M | $59M | $47M | $39M | $36M | $31M | |
| Restructuring | · | · | · | · | · | · | · | · | · | · | · | $23M | $8M | · | · | · | |
| Other Non-cash | · | $-95M | · | · | · | $-22M | · | · | · | $89M | · | · | · | $38M | · | · | |
| Operating Cash Flow | $129M | $-59M | $-34M | $-66M | $-58M | $870M | $-30M | $-77M | $-71M | $71M | $-100M | $-15M | $-14M | $-29M | $-166M | $-38M | |
| CapEx | $2M | $1M | $2M | $3M | $1M | $2M | $4M | $522.0K | $-7M | $10M | $6M | $6M | $6M | $10M | $9M | $5M | |
| Investing Cash Flow | $-123M | $-94M | $34M | $-290M | $-422M | $-184M | $268M | $-43M | $-66M | $-115M | $-94M | $-30M | $-24M | $-29M | $32M | $136M | |
| Financing Cash Flow | $212M | $6M | $303M | $15M | $4M | $9M | $26M | $-18M | $246M | $540.0K | $620M | $3M | $18M | $4M | $303M | $-140M | |
| Net Change in Cash | $216M | $-148M | $312M | $-347M | $-463M | $701M | $256M | $-129M | $104M | $-46M | $429M | $-43M | $-9M | $-62M | $175M | $-54M | |
| Taxes Paid | · | · | $-3M | $936.0K | $36M | $3M | $5M | $7M | $4M | $2M | $524.0K | $4M | $7M | $2M | $893.0K | $1M | |
| Free Cash Flow | · | $-60M | · | · | · | $868M | · | · | · | $61M | · | · | · | $-40M | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | 41.3% | 16.5% | · | 1.4% | -19.5% | 82.5% | · | -27.7% | -21.5% | -21.6% | · | -60.1% | -98.0% | -53.4% | · | -31.4% | |
| Net Margin | 23.2% | -1.0% | · | 7.5% | -36.2% | 73.7% | · | -54.2% | -53.1% | -43.6% | · | -67.6% | -93.0% | -63.0% | · | -50.3% | |
| Pretax Margin | 27.1% | -0.90% | · | -10.9% | -39.7% | 79.1% | · | -49.8% | -45.9% | -40.3% | · | -84.8% | -111.1% | -61.3% | · | -58.6% | |
| EBITDA Margin | 41.3% | 22.1% | · | 1.4% | -19.5% | 83.1% | · | -27.7% | -21.5% | 4.7% | · | -60.1% | -98.0% | -33.9% | · | -31.4% | |
| ROA | 2.8% | -0.10% | · | 0.71% | -2.9% | 39.0% | · | -6.9% | -6.1% | -5.4% | · | -9.4% | -12.7% | -8.2% | · | -6.1% | |
| ROE | -44.9% | 1.5% | · | -2.6% | 10.9% | -160.5% | · | 12.4% | 12.7% | 13.6% | · | 29.6% | 52.2% | 50.7% | · | 179.2% | |
| ROIC | 30.0% | 48.2% | · | -1.6% | -40.2% | 904.6% | · | 7.7% | 6.7% | 8.1% | · | 96.6% | 2648.9% | -105.7% | · | -104.9% |
Liquidez y Solvencia 4
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.4 | 2.4 | · | 2.3 | 3.6 | 3.9 | · | 2.1 | 2.2 | 2.0 | · | 1.1 | 1.2 | 1.4 | · | 1.2 | |
| Quick Ratio | 3.2 | 2.3 | · | 2.2 | 3.5 | 3.8 | · | 2.0 | 2.1 | 1.9 | · | 0.9 | 1.1 | 1.1 | · | 1.0 | |
| Debt / Equity | -3.6 | -1.6 | · | -1.8 | -1.4 | -1.5 | · | -0.3 | -0.3 | -0.3 | · | -0.9 | -1.0 | -1.3 | · | -1.2 | |
| LT Debt / Equity | -3.2 | · | · | · | -1.4 | -1.5 | · | -0.3 | -0.3 | -0.3 | · | -0.9 | -1.0 | -1.3 | · | -1.2 |
Eficiencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.1 | · | 0.1 | 0.1 | 0.5 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | |
| Receivables Turnover | 1.7 | 1.3 | · | 1.0 | 0.9 | 5.8 | · | 1.1 | 1.0 | 1.1 | · | 1.4 | 1.4 | 1.3 | · | 2.0 |
Valoración (TTM) 13
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $1.02B | $1.84B | · | $1.76B | $1.74B | $1.77B | · | $790M | $807M | $841M | · | $848M | $817M | $752M | · | $670M | |
| Net Income TTM | $32M | $815M | · | $711M | $596M | $569M | · | $-430M | $-523M | $-562M | · | $-580M | $-599M | $-527M | · | $-522M | |
| Market Cap | $6.80B | $5.65B | · | $4.91B | $3.88B | $4.04B | · | $2.85B | $2.35B | $2.23B | · | $1.69B | $3.06B | $3.59B | · | $3.61B | |
| Enterprise Value | $5.16B | $4.04B | · | $3.50B | $2.17B | $2.30B | · | $2.13B | $1.54B | $1.63B | · | $1.97B | $3.30B | $3.87B | · | $3.60B | |
| P/E | 313.7 | 7.3 | · | 7.7 | 7.5 | 8.3 | · | -6.6 | -4.4 | -3.9 | · | -2.9 | -5.0 | -6.6 | · | -6.8 | |
| P/S | 6.6 | 3.1 | · | 2.8 | 2.2 | 2.3 | · | 3.6 | 2.9 | 2.7 | · | 2.0 | 3.8 | 4.8 | · | 5.4 | |
| P/B | -41.1 | -31.3 | · | -31.5 | -18.8 | -21.7 | · | -2.7 | -2.4 | -2.5 | · | -2.5 | -5.3 | -7.8 | · | -15.9 | |
| P / Cash Flow | · | -95.6 | · | · | · | 4.6 | · | · | · | 31.5 | · | · | · | -121.6 | · | · | |
| P / FCF | · | -93.7 | · | · | · | 4.6 | · | · | · | 36.5 | · | · | · | -90.2 | · | · | |
| EV / EBITDA | 34.6 | 66.9 | · | 1161.8 | -62.2 | 2.3 | · | -39.0 | -38.4 | 163.9 | · | -16.7 | -15.7 | -51.8 | · | -52.8 | |
| EV / FCF | · | -67.1 | · | · | · | 2.6 | · | · | · | 26.6 | · | · | · | -97.4 | · | · | |
| EV / Revenue | 5.0 | 2.2 | · | 2.0 | 1.3 | 1.3 | · | 2.7 | 1.9 | 1.9 | · | 2.3 | 4.0 | 5.1 | · | 5.4 | |
| Earnings Yield | 0.32% | 13.8% | · | 13.1% | 13.4% | 12.1% | · | -15.2% | -22.6% | -25.8% | · | -34.9% | -20.2% | -15.1% | · | -14.6% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $1.73B | $807M | $938M | $699M | $539M |
| Margen Operativo % | 50.1% | -37.5% | -46.9% | — | -69.5% |
| Beneficio neto | $683M | $-363M | $-627M | $-559M | $-524M |
| EPS Diluido | $7.78 | $-4.73 | $-8.37 | $-7.79 | $-7.43 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Deuda / Patrimonio | -1.4 | -0.3 | -0.3 | — | 300.0 |
| Ratio corriente | 2.3 | 2.4 | 2.0 | — | 1.9 |
| Ratio Rápido | 2.2 | 2.2 | 1.7 | — | 1.7 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $702M | $-114M | $-187M | — | $-280M |
Señales de trading Señales recientes de compra/venta con precio de entrada y ratio riesgo/recompensa
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Propietarios institucionales (13F) 405 declarantes · $5.4B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 84 (+17 vs trimestre anterior) | 43 (-7 vs trimestre anterior) | 133 (-6 vs trimestre anterior) | 109 (+6 vs trimestre anterior) | -7.1M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| RTW INVESTMENTS, LP | $631 875 072 | 7 746 415 | 11,70% | Acciones |
| JANUS HENDERSON GROUP PLC | $479 178 655 | 7 034 622 | 8,87% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $401 986 014 | 4 928 111 | 7,44% | Acciones |
| STATE STREET CORP | $375 136 515 | 4 598 952 | 6,95% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $305 000 589 | 3 739 127 | 5,65% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $292 435 873 | 3 585 091 | 5,42% | Acciones |
| WESTFIELD CAPITAL MANAGEMENT CO LP | $159 563 645 | 1 956 156 | 2,95% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $155 132 041 | 1 901 417 | 2,87% | Acciones |
| Hood River Capital Management LLC | $141 818 662 | 1 738 613 | 2,63% | Acciones |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $140 519 660 | 1 722 688 | 2,60% | Acciones |
| TANG CAPITAL MANAGEMENT LLC | $122 355 000 | 1 500 000 | 2,27% | Acciones |
| Driehaus Capital Management LLC | $117 469 528 | 1 440 107 | 2,18% | Acciones |
| Jefferies Financial Group Inc. | $110 693 916 | 1 357 042 | 2,05% | Acciones |
| FULLER & THALER ASSET MANAGEMENT, INC. | $94 361 749 | 1 156 819 | 1,75% | Acciones |
| Pictet Asset Management Holding SA | $93 629 635 | 1 147 844 | 1,73% | Acciones |
| ARMISTICE CAPITAL, LLC | $87 393 690 | 1 071 395 | 1,62% | Acciones |
| Blue Sparrow, LLC /DE | $85 705 599 | 1 050 700 | 1,59% | Acciones |
| D. E. Shaw & Co., Inc. | $77 478 857 | 949 845 | 1,43% | Acciones |
| Palo Alto Investors LP | $74 950 268 | 918 846 | 1,39% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $64 449 436 | 790 112 | 1,19% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $59 015 895 | 723 500 | 1,09% | Acciones |
| Boston Partners | $57 080 953 | 699 871 | 1,06% | Acciones |
| FMR LLC | $56 956 987 | 698 259 | 1,05% | Acciones |
| BANK OF AMERICA CORP /DE/ | $56 350 840 | 690 828 | 1,04% | Acciones |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $53 377 940 | 654 382 | 0,99% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $51 486 821 | 631 199 | 0,95% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $47 953 943 | 587 887 | 0,89% | Acciones |
| Ensign Peak Advisors, Inc | $41 442 128 | 508 056 | 0,77% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $40 866 277 | 500 995 | 0,76% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $36 050 432 | 441 957 | 0,67% | Acciones |
| Parkman Healthcare Partners LLC | $35 539 315 | 435 691 | 0,66% | Acciones |
| LOOMIS SAYLES & CO L P | $35 387 921 | 433 835 | 0,66% | Acciones |
| Defilade Capital Management, L.P. | $35 376 827 | 433 699 | 0,66% | Acciones |
| GOLDMAN SACHS GROUP INC | $34 153 522 | 418 702 | 0,63% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $32 274 149 | 395 662 | 0,60% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $30 892 190 | 378 720 | 0,57% | Acciones |
| Qube Research & Technologies Ltd | $25 398 777 | 311 374 | 0,47% | Acciones |
| ARMISTICE CAPITAL, LLC | $24 471 000 | 300 000 | 0,45% | Opción de compra |
| Public Sector Pension Investment Board | $23 249 326 | 285 023 | 0,43% | Acciones |
| SEGALL BRYANT & HAMILL, LLC | $22 165 424 | 271 735 | 0,41% | Acciones |
| CITADEL ADVISORS LLC | $20 338 011 | 249 332 | 0,38% | Acciones |
| MORGAN STANLEY | $18 990 210 | 232 808 | 0,35% | Acciones |
| Boxer Capital Management, LLC | $16 314 000 | 200 000 | 0,30% | Acciones |
| RHUMBLINE ADVISERS | $15 718 994 | 192 706 | 0,29% | Acciones |
| AMERIPRISE FINANCIAL INC | $13 904 178 | 170 457 | 0,26% | Acciones |
| PRUDENTIAL FINANCIAL INC | $13 746 176 | 168 520 | 0,25% | Acciones |
| BlackRock, Inc. | $13 589 562 | 166 600 | 0,25% | Acciones |
| Rock Springs Capital Management LP | $13 238 648 | 162 298 | 0,25% | Acciones |
| Hudson Bay Capital Management LP | $13 033 091 | 159 778 | 0,24% | Acciones |
| Russell Investments Group, Ltd. | $12 687 724 | 155 544 | 0,23% | Acciones |
| Schonfeld Strategic Advisors LLC | $12 025 457 | 147 425 | 0,22% | Acciones |
| MARSHALL WACE, LLP | $11 724 301 | 143 733 | 0,22% | Acciones |
| Swiss National Bank | $11 539 300 | 141 465 | 0,21% | Acciones |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $11 063 583 | 135 633 | 0,20% | Acciones |
| Legal & General Group Plc | $10 362 979 | 127 044 | 0,19% | Acciones |
| CITIGROUP INC | $9 272 143 | 113 671 | 0,17% | Acciones |
| FIRST TRUST ADVISORS LP | $9 246 285 | 113 354 | 0,17% | Acciones |
| Longaeva Partners L.P. | $9 119 771 | 111 803 | 0,17% | Acciones |
| JUPITER ASSET MANAGEMENT LTD | $8 927 184 | 109 442 | 0,17% | Acciones |
| SCHRODER INVESTMENT MANAGEMENT GROUP | $8 215 404 | 100 716 | 0,15% | Acciones |
| SECTOR GAMMA AS | $8 157 000 | 100 000 | 0,15% | Acciones |
| WCM INVESTMENT MANAGEMENT, LLC | $7 651 184 | 93 799 | 0,14% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $7 256 141 | 88 956 | 0,13% | Acciones |
| VOYA INVESTMENT MANAGEMENT LLC | $7 239 501 | 88 752 | 0,13% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $7 217 488 | 105 937 | 0,13% | Acciones |
| Aquatic Capital Management LLC | $6 808 648 | 83 470 | 0,13% | Acciones |
| XTX Topco Ltd | $6 682 459 | 81 923 | 0,12% | Acciones |
| MOORE CAPITAL MANAGEMENT, LP | $6 165 713 | 75 588 | 0,11% | Acciones |
| PINNACLE ASSOCIATES LTD | $5 745 383 | 70 435 | 0,11% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $5 744 722 | 84 320 | 0,11% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $5 614 300 | 68 828 | 0,10% | Acciones |
| Capricorn Fund Managers Ltd | $5 212 323 | 63 900 | 0,10% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5 000 241 | 61 300 | 0,09% | Opción de compra |
| INTECH INVESTMENT MANAGEMENT LLC | $4 696 882 | 57 581 | 0,09% | Acciones |
| ExodusPoint Capital Management, LP | $4 672 166 | 57 278 | 0,09% | Acciones |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $4 561 884 | 55 926 | 0,08% | Acciones |
| BARCLAYS PLC | $4 169 858 | 51 120 | 0,08% | Acciones |
| ORBIMED ADVISORS LLC | $4 005 087 | 49 100 | 0,07% | Acciones |
| MetLife Investment Management, LLC | $3 932 653 | 48 212 | 0,07% | Acciones |
| Point72 Europe (London) LLP | $3 829 919 | 62 407 | 0,07% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $3 792 516 | 46 494 | 0,07% | Acciones |
| Phocas Financial Corp. | $3 766 087 | 46 170 | 0,07% | Acciones |
| MARTINGALE ASSET MANAGEMENT L P | $3 627 826 | 44 475 | 0,07% | Acciones |
| Quadrature Capital Ltd | $3 589 488 | 44 005 | 0,07% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3 531 981 | 43 300 | 0,07% | Opción de venta |
| STATE OF WISCONSIN INVESTMENT BOARD | $3 436 299 | 42 127 | 0,06% | Acciones |
| CREDIT AGRICOLE S A | $3 344 370 | 41 000 | 0,06% | Acciones |
| Fisher Asset Management, LLC | $3 322 345 | 40 730 | 0,06% | Acciones |
| HSBC HOLDINGS PLC | $3 200 425 | 38 732 | 0,06% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $3 134 490 | 38 427 | 0,06% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $3 114 179 | 38 178 | 0,06% | Acciones |
| CenterBook Partners LP | $3 082 938 | 37 795 | 0,06% | Acciones |
| Rafferty Asset Management, LLC | $3 069 805 | 37 634 | 0,06% | Acciones |
| FIFTH THIRD BANCORP | $3 044 843 | 37 328 | 0,06% | Acciones |
| BURNEY CO/ | $3 044 192 | 37 320 | 0,06% | Acciones |
| Vanguard Global Advisers, LLC | $3 033 180 | 37 185 | 0,06% | Acciones |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $3 007 731 | 36 873 | 0,06% | Acciones |
| Louisiana State Employees Retirement System | $2 969 148 | 36 400 | 0,05% | Acciones |
| JANE STREET GROUP, LLC | $2 854 950 | 35 000 | 0,05% | Opción de venta |
| CASTLEARK MANAGEMENT LLC | $2 765 223 | 33 900 | 0,05% | Acciones |
Informantes de la empresa 33 insiders · 13 directivos · 14 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Stuart Walter Peltz | Chief Executive Officer | 1 de febrero de 2022 S | 38 728 | 0 | 0 | $0 |
| Pierre Gravier | CHIEF FINANCIAL OFFICER | 14 de julio de 2026 S | 83 986 | 0 | 1 | $-280 743 |
| Emily Luisa Hill | Chief Financial Officer | 1 de febrero de 2022 S | 37 169 | 0 | 0 | $0 |
| Shane William Charles Kovacs | Chief Financial Officer | 9 de mayo de 2017 M | 37 850 | 0 | 0 | $0 |
| Claudia De Oliveira Ribeiro Hirawat | President | 15 de enero de 2015 M | 39 247 | 0 | 0 | $0 |
| Marcio Souza | Chief Operating Officer | 10 de febrero de 2020 M | 6 744 | 0 | 0 | $0 |
| Neil Gregory Almstead | CHIEF TECHNICAL OPS OFFICER | 9 de julio de 2026 M | 60 299 | 0 | 20 | $-9 184 852 |
| Mark Elliott Boulding | EXEC. VP AND CLO | 6 de julio de 2026 M | 105 272 | 0 | 12 | $-1 254 986 |
| Christine Marie Utter | SVP, CHIEF ACCOUNTING OFFICER | 17 de junio de 2026 M | 70 199 | 0 | 1 | $-1 487 474 |
| Eric Pauwels | CHIEF BUSINESS OFFICER | 10 de junio de 2026 S | 73 411 | 0 | 28 | $-7 477 160 |
| Mark Rothera | Chief Commercial Officer | 24 de mayo de 2017 M | 33 739 | 0 | 0 | $0 |
| Tuyen Ong | Chief Medical Officer | 3 de enero de 2017 A | 6 000 | 0 | 0 | $0 |
| Robert J. Spiegel | Chief Medical Officer | 4 de enero de 2016 A | 3 239 | 0 | 0 | $0 |
| Hege Elisabeth Sollie-Zetlmayer | Consejero | 28 de julio de 2026 A | 52 526 | 0 | 0 | $0 |
| Mary L. Smith | Consejero | 9 de julio de 2026 M | 21 813 | 0 | 2 | $-1 425 060 |
| Stephanie Okey | Consejero | 7 de enero de 2022 A | 4 163 | 0 | 0 | $0 |
| Emma Reeve | Consejero | 7 de enero de 2022 A | 7 528 | 0 | 0 | $0 |
| Allan Steven Jacobson | Consejero | 7 de enero de 2022 A | 8 348 | 0 | 0 | $0 |
| Dawn Svoronos | Consejero | 7 de enero de 2022 A | 29 755 | 0 | 0 | $0 |
| Jerome B Zeldis | Consejero | 7 de enero de 2022 A | 6 500 | 0 | 0 | $0 |
| Cameron Geoffrey Mcdonough | Consejero | 3 de enero de 2017 A | — | 0 | 0 | $0 |
| Adam Koppel | Consejero | 3 de enero de 2017 A | 2 333 333 | 0 | 0 | $0 |
| Ronald C Renaud JR | Consejero | 3 de enero de 2017 A | — | 0 | 0 | $0 |
| Richard Aldrich | Consejero | 8 de junio de 2015 M | 0 | 0 | 0 | $0 |
| Michael L Kranda | Consejero | 16 de marzo de 2015 S | 2 242 | 0 | 0 | $0 |
| Axel Bolte | Consejero | 25 de junio de 2013 P | 20 000 | 0 | 0 | $0 |
| HBM Healthcare Investments (Cayman) Ltd. | Propietario del 10% | 17 de diciembre de 2013 S | 2 441 504 | 0 | 0 | $0 |
| Matthew B. Klein | — | 4 de agosto de 2026 S | 383 868 | 0 | 1 | $-705 722 |
| Michael Schmertzler | — | 2 de enero de 2026 A | 163 266 | 0 | 0 | $0 |
| Glenn Steele JR MD PHD | — | 2 de enero de 2026 A | 22 500 | 0 | 1 | $-916 200 |
| David P Southwell | — | 2 de enero de 2026 A | 20 850 | 0 | 0 | $0 |
| Complete Pharma Holdings II, LLC | — | 28 de abril de 2017 J | 0 | 0 | 0 | $0 |
| CREDIT SUISSE/ | — | 25 de junio de 2013 C | 2 256 882 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 3 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Brookside Capital Partners Fund, L.P., Brookside Capital Trading Fund, L.P. ×5 presentaciones | 30 de enero de 2015 | — | Presentación inicial | — | SEC |
| HBM Healthcare Investments (Cayman) Ltd. (“HBM”) ×2 presentaciones | 12 de noviembre de 2014 | — | Presentación inicial | — | SEC |
| HBM Healthcare Investments (Cayman) Ltd. | 5 de julio de 2013 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 88 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| BBP · ETFis Series Trust I | 1,37% | 12 510 NS | 30 de abril de 2026 | N-PORT |
| SIXS · EXCHANGE TRADED CONCEPTS TRUST | 1,30% | 22 380 NS | 31 de mayo de 2026 | N-PORT |
| GURU · Global X Funds | 1,03% | 9 268 NS | 30 de abril de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,93% | 73 928 NS | 30 de abril de 2026 | N-PORT |
| VAMO · Cambria ETF Trust | 0,83% | 10 625 NS | 30 de abril de 2026 | N-PORT |
| VMAX · Lattice Strategies Trust | 0,72% | 5 120 NS | 30 de abril de 2026 | N-PORT |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,51% | 40 257 NS | 30 de abril de 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,49% | 3 490 NS | 31 de mayo de 2026 | N-PORT |
| CLSE · Trust for Professional Managers | 0,49% | 40 488 NS | 31 de mayo de 2026 | N-PORT |
| PSC · Principal Exchange-Traded Funds | 0,47% | 135 289 NS | 30 de junio de 2026 | N-PORT |
| HQGO · Lattice Strategies Trust | 0,43% | 3 203 NS | 30 de abril de 2026 | N-PORT |
| OASC · Unified Series Trust | 0,40% | 4 569 NS | 31 de mayo de 2026 | N-PORT |
| BRNY · EA Series Trust | 0,40% | 34 057 NS | 30 de abril de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,34% | 35 034 NS | 31 de mayo de 2026 | N-PORT |
| ESSC · Strategy Shares | 0,34% | 1 335 NS | 30 de abril de 2026 | N-PORT |
| BIB · ProShares Trust | 0,31% | 3 062 NS | 31 de mayo de 2026 | N-PORT |
| FSCC · Federated Hermes ETF Trust | 0,31% | 11 451 NS | 31 de mayo de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,30% | 39 411 NS | 31 de mayo de 2026 | N-PORT |
| SAA · ProShares Trust | 0,26% | 961 NS | 31 de mayo de 2026 | N-PORT |
| ROUS · Lattice Strategies Trust | 0,25% | 22 443 NS | 30 de abril de 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,24% | 27 276 NS | 30 de abril de 2026 | N-PORT |
| BKSE · BNY Mellon ETF Trust | 0,23% | 2 877 NS | 30 de abril de 2026 | N-PORT |
| AFSM · First Trust Exchange-Traded Fund VI… | 0,23% | 3 003 NS | 31 de mayo de 2026 | N-PORT |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,20% | 39 967 NS | 30 de abril de 2026 | N-PORT |
| RSSL · Global X Funds | 0,16% | 34 125 NS | 30 de abril de 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,15% | 11 071 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,15% | 3 710 NS | 31 de mayo de 2026 | N-PORT |
| FSMD · FIDELITY COVINGTON TRUST | 0,14% | 49 932 NS | 30 de abril de 2026 | N-PORT |
| SMDX · Tidal Trust III | 0,13% | 2 579 NS | 30 de abril de 2026 | N-PORT |
| SXQG · EXCHANGE TRADED CONCEPTS TRUST | 0,13% | 1 182 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,13% | 386 068 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,09% | 190 421 NS | 30 de abril de 2026 | N-PORT |
| UWM · ProShares Trust | 0,09% | 2 899 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,08% | 33 415 NS | 30 de abril de 2026 | N-PORT |
| FYEE · Fidelity Greenwood Street Trust | 0,07% | 1 913 NS | 30 de abril de 2026 | N-PORT |
| URTY · ProShares Trust | 0,06% | 2 936 NS | 31 de mayo de 2026 | N-PORT |
| FBUF · Fidelity Greenwood Street Trust | 0,05% | 154 NS | 30 de abril de 2026 | N-PORT |
| AFMC · First Trust Exchange-Traded Fund VI… | 0,05% | 1 112 NS | 31 de mayo de 2026 | N-PORT |
| TILT · FlexShares Trust | 0,04% | 13 552 NS | 30 de abril de 2026 | N-PORT |
| HDG · ProShares Trust | 0,03% | 74 NS | 31 de mayo de 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,02% | 6 829 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,01% | 95 919 NS | 30 de abril de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 17 796 NS | 31 de mayo de 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,01% | 47 658 NS | 31 de mayo de 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,01% | 506 NS | 31 de mayo de 2026 | N-PORT |
| AVUQ · AMERICAN CENTURY ETF TRUST | 0,01% | 273 NS | 31 de mayo de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,01% | 21 258 NS | 30 de abril de 2026 | N-PORT |
| FHEQ · Fidelity Greenwood Street Trust | 0,01% | 861 NS | 30 de abril de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 7 872 NS | 30 de abril de 2026 | N-PORT |
| FTLS · First Trust Exchange-Traded Fund III | -0,10% | -33 590 NS | 30 de abril de 2026 | N-PORT |