MIRM Mirum Pharmaceuticals, Inc. - common stock
$96,33
Precio · Ago 24, 2026
Fundamentales a fecha de Ago 5, 2026
Rango 52S
$63–$130
50% of range
Calificación del Analista
BUY
20 analysts
Precio Objetivo
$138
+43% upside
P/E (TTM)
-205.0
ROE
-8.2%
Margen de Beneficio Neto
-4.5%
Acerca de Mirum Pharmaceuticals, Inc. - common stock Descripción general de la empresa de Wikipedia
MIRM Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$96.33
Capitalización Bursátil
$5.00B
P/E (TTM)
-205.0
BPA (TTM)
$-0.47
Ingresos (TTM)
$521M
Rendimiento div.
—
ROE
-8.2%
Deuda/Capital
—
Rango 52S
$63 – $130
MIRM Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
$521M
2020-12-31
→
2025-12-31
BPA
$-0.47
2021-12-31
→
2025-12-31
Flujo de caja libre
$55M
2019-12-31
→
2025-12-31
Márgenes
-4.5%
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
MIRM
Mediana de Pares
P/E (TTM)
-205.0
16.0
P/S (TTM) (P/V (TTM))
9.6
47.5
P/B (P/C)
15.9
8.5
Price / FCF (Precio / FCF)
91.1
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
MIRM
Mediana de Pares
Operating Margin (Margen Operativo)
-4.2%
—
Net Profit Margin (Margen de Beneficio Neto)
-4.5%
-140.2%
ROA
-3.1%
-45.0%
ROE
-8.2%
-86.5%
ROIC
-7.7%
—
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
MIRM
Mediana de Pares
Current Ratio (Ratio corriente)
2.7
5.8
Quick Ratio (Ratio Rápido)
2.5
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
MIRM
Mediana de Pares
Revenue YoY (Ingresos interanuales)
54.7%
—
Revenue CAGR 3Y (Ingresos CAGR 3A)
89.1%
—
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
MIRM
Mediana de Pares
MIRM Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
20 analistas
- Compra fuerte 8 40,0%
- Compra 11 55,0%
- Mantener 1 5,0%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
14 analistas · 2026-08-18
Mediana
$137.00
← Por Debajo de Todos los Objetivos
$96.33
Mín
$118.00
Máx
$183.00
Objetivo mediano
$137.00
+42,2%
Objetivo medio
$138.21
+43,5%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
-0.13%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-1.06 | $-0.69 | -0.37% |
| 31 de marzo de 2026 | $-1.08 | $-0.36 | -0.72% |
| 31 de diciembre de 2025 | $-0.10 | $0.04 | -0.14% |
| 30 de septiembre de 2025 | $0.05 | $-0.17 | 0.22% |
| 30 de junio de 2025 | $-0.12 | $-0.33 | 0.21% |
| 31 de marzo de 2025 | $-0.30 | $-0.34 | 0.04% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| MIRM | $4.10B | -168.1 | 54.7% | -4.5% | -8.2% | — |
| CGON | $3.35B | -20.0 | 254.7% | -3985.0% | -22.6% | — |
| SRRK | $4.78B | -13.4 | — | — | -157.9% | — |
| COGT | $5.72B | -16.4 | — | — | -83.1% | — |
| DNTH | $1.78B | -9.8 | -67.3% | -7973.3% | -40.8% | — |
| ERAS | $1.06B | -8.5 | — | — | -35.7% | — |
| TVTX | $3.47B | -131.8 | 110.5% | -5.2% | -34.6% | — |
| PTCT | $6.19B | 9.8 | 114.5% | 39.4% | -331.5% | — |
| ACAD | $4.55B | 11.6 | 11.9% | 36.5% | 38.1% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue | $521M | $337M | $186M | $77M | $19M | $0 | |
| SG&A Expense | $257M | $202M | $146M | $89M | $59M | $23M | |
| Operating Expenses | $543M | $424M | $296M | $208M | $193M | $104M | |
| Operating Income | $-22M | $-88M | $-109M | $-131M | $-173M | $-104M | |
| Interest Income | $13M | $14M | $14M | $4M | $366.0K | $2M | |
| Other Non-op | $2M | $1M | $-3M | $365.0K | $-582.0K | $-192.0K | |
| Pretax Income | $-21M | $-87M | $-162M | $-142M | $-84M | $-103M | |
| Income Tax | $2M | $1M | $991.0K | $-6M | $37.0K | $6.0K | |
| Net Income | $-23M | $-88M | $-163M | $-136M | $-84M | $-103M | |
| EPS (Basic) | $-0.47 | $-1.85 | $-4.00 | $-4.01 | $-2.77 | · | |
| EPS (Diluted) | $-0.47 | $-1.85 | $-4.00 | $-4.02 | $-2.77 | · | |
| Shares (Basic) | 50,198,304 | 47,522,594 | 40,885,124 | 33,839,072 | 30,321,722 | · | |
| Shares (Diluted) | 50,198,304 | 47,522,594 | 40,885,124 | 33,982,493 | 30,321,722 | · | |
| EBITDA | $2M | $-64M | $-98M | $-128M | $-173M | $-104M |
Balance general 23
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $297M | $223M | $286M | $28M | $31M | $142M | |
| Short-term Investments | $87M | $58M | $0 | $124M | $125M | $90M | |
| Receivables | $123M | $78M | $68M | $24M | $3M | $0 | |
| Inventory | $25M | $22M | $22M | $6M | $2M | $0 | |
| Prepaid Expense | $18M | $12M | $11M | $9M | $5M | $5M | |
| Current Assets | $550M | $393M | $388M | $190M | $167M | $236M | |
| PP&E (Net) | $2M | $1M | $706.0K | $914.0K | $981.0K | $1M | |
| Accum. Depreciation | $1M | $700.0K | $2M | $1M | $700.0K | $300.0K | |
| Intangibles | $261M | $250M | $253M | $59M | $19M | $0 | |
| Other Non-current Assets | $12M | $5M | $4M | $1M | $2M | $1M | |
| Total Assets | $843M | $671M | $647M | $353M | $295M | $241M | |
| Accounts Payable | $10M | $15M | $7M | $9M | $9M | $3M | |
| Accrued Liabilities | $196M | $112M | $79M | $54M | $31M | $13M | |
| Current Liabilities | $206M | $127M | $87M | $65M | $43M | $18M | |
| Capital Leases | $8M | $8M | $617.0K | $1M | $2M | $3M | |
| Other Non-current Liabilities | $5M | $3M | $4M | $5M | $17.0K | $29.0K | |
| Total Liabilities | $528M | $445M | $398M | $211M | $174M | $69M | |
| Common Stock | $5.0K | $5.0K | $5.0K | $4.0K | $3.0K | $3.0K | |
| Retained Earnings | $-668M | $-644M | $-556M | $-393M | $-257M | $-173M | |
| AOCI | $351.0K | $-373.0K | $2M | $-217.0K | $-35.0K | $83.0K | |
| Stockholders' Equity | $315M | $226M | $249M | $142M | $120M | $172M | |
| Liabilities + Equity | $843M | $671M | $647M | $353M | $295M | $241M | |
| Shares Outstanding | 51,896,391 | 48,338,096 | 46,723,143 | 36,956,345 | 30,582,596 | 29,776,544 |
Flujo de Efectivo 14
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $24M | $24M | $11M | $3M | $595.0K | $305.0K | |
| Stock-based Comp | $71M | $48M | $35M | $27M | $23M | $13M | |
| Deferred Tax | $0 | $0 | $0 | $-7M | $0 | · | |
| Amort. of Intangibles | $24M | $23M | $10M | $3M | $300.0K | · | |
| Other Non-cash | $-16M | $26M | $47M | $-8M | $-72M | $1M | |
| Operating Cash Flow | $56M | $10M | $-71M | $-120M | $-133M | $-89M | |
| CapEx | $954.0K | $993.0K | $109.0K | $278.0K | $24.0K | $225.0K | |
| Investing Cash Flow | $-24M | $-90M | $-107M | $8M | $49M | $38M | |
| Stock Issued | $0 | $0 | $14M | $21M | $0 | · | |
| Net Stock Activity | $0 | $0 | $14M | $21M | · | · | |
| Financing Cash Flow | $40M | $18M | $337M | $109M | $73M | $181M | |
| Net Change in Cash | $75M | $-63M | $158M | $-3M | $-11M | $130M | |
| Taxes Paid | $2M | $1M | $125.0K | $0 | · | · | |
| Free Cash Flow | $55M | $9M | $-71M | $-120M | $-133M | $-89M |
Rentabilidad 7
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Operating Margin | -4.2% | -26.0% | -58.6% | -170.3% | -906.1% | · | |
| Net Margin | -4.5% | -26.1% | -87.7% | -176.0% | -438.8% | · | |
| Pretax Margin | -4.1% | -25.8% | -87.2% | -184.4% | -438.7% | · | |
| EBITDA Margin | 0.40% | -19.0% | -52.8% | -166.1% | -903.0% | · | |
| ROA | -3.1% | -13.4% | -32.7% | -41.9% | -31.4% | -53.3% | |
| ROE | -8.2% | -38.4% | -63.1% | -87.2% | -95.1% | -70.7% | |
| ROIC | -7.7% | -39.3% | -44.2% | -88.2% | -144.3% | -60.6% |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 2.7 | 3.1 | 4.5 | 2.9 | 3.9 | 12.8 | |
| Quick Ratio | 2.5 | 2.8 | 4.1 | 2.7 | 3.8 | 12.6 |
Eficiencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.7 | 0.5 | 0.4 | 0.2 | 0.1 | · | |
| Receivables Turnover | 5.2 | 4.6 | 4.1 | 5.7 | 11.7 | · |
Tasas de Crecimiento 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue YoY | 54.7% | 80.8% | 141.9% | 302.7% | · | · | |
| Revenue CAGR 3Y | 89.1% | 160.1% | · | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Revenue TTM | $521M | $337M | $186M | $77M | $19M | $0 | |
| Net Income TTM | $-23M | $-88M | $-163M | $-136M | $-84M | $-103M | |
| Market Cap | $4.10B | $2.00B | $1.38B | $721M | $488M | $520M | |
| P/E | -168.1 | -22.4 | -7.4 | -4.9 | -5.8 | · | |
| P/S | 7.9 | 5.9 | 7.4 | 9.4 | 25.5 | · | |
| P/B | 13.0 | 8.9 | 5.5 | 5.1 | 4.1 | 3.0 | |
| P / Tangible Book | 76.2 | · | · | 8.7 | 4.8 | 3.0 | |
| P / Cash Flow | 73.4 | 193.6 | -19.4 | -6.0 | -3.7 | -5.8 | |
| P / FCF | 74.7 | 214.2 | -19.4 | -6.0 | -3.7 | -5.8 | |
| Earnings Yield | -0.60% | -4.5% | -13.6% | -20.6% | -17.4% | · |
Estado de resultados 14
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $176M | $160M | $149M | $133M | $128M | $112M | $99M | $90M | $78M | $69M | $70M | $48M | $37M | $32M | $28M | $19M | |
| SG&A Expense | $81M | $96M | $74M | $62M | $63M | $58M | $57M | $51M | $49M | $46M | $46M | $37M | $33M | $30M | $26M | $23M | |
| Operating Expenses | $219M | $949M | $153M | $130M | $133M | $127M | $124M | $103M | $102M | $96M | $102M | $73M | $62M | $59M | $62M | $52M | |
| Operating Income | $-43M | $-789M | $-5M | $3M | $-5M | $-15M | $-24M | $-13M | $-24M | $-26M | $-33M | $-25M | $-24M | $-27M | $-34M | $-33M | |
| Interest Income | $4M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $4M | $4M | $2M | $2M | $1M | |
| Other Non-op | $-24M | $0 | $-218.0K | $395.0K | $86.0K | $2M | $231.0K | $-1M | $312.0K | $2M | $-3M | $1M | $-274.0K | $-811.0K | $-588.0K | $-192.0K | |
| Pretax Income | $-66M | $-790M | $-5M | $3M | $-5M | $-14M | $-24M | $-14M | $-24M | $-25M | $-35M | $-23M | $-74M | $-30M | $-36M | $-36M | |
| Income Tax | $2M | $475.0K | $767.0K | $-262.0K | $402.0K | $1M | $-576.0K | $347.0K | $635.0K | $624.0K | $225.0K | $249.0K | $316.0K | $201.0K | $140.0K | $13.0K | |
| Net Income | $-67M | $-790M | $-6M | $3M | $-6M | $-15M | $-24M | $-14M | $-25M | $-25M | $-36M | $-24M | $-74M | $-30M | $-36M | $-36M | |
| EPS (Basic) | $-1.06 | $-13.43 | $-0.11 | $0.06 | $-0.12 | $-0.30 | $-0.49 | $-0.30 | $-0.52 | $-0.54 | $-0.69 | $-0.57 | $-1.94 | $-0.80 | $-0.98 | $-1.02 | |
| EPS (Diluted) | $-1.06 | $-13.43 | $-0.10 | $0.05 | $-0.12 | $-0.30 | $-0.49 | $-0.30 | $-0.52 | $-0.54 | $-0.69 | $-0.57 | $-1.94 | $-0.80 | $-0.99 | $-1.02 | |
| Shares (Basic) | 63,374,183 | 58,851,021 | -99,056,808 | 50,639,231 | 49,726,823 | 48,889,058 | -94,422,655 | 47,782,619 | 47,235,080 | 46,927,550 | -75,996,436 | 41,098,920 | 38,107,334 | 37,675,306 | -64,549,115 | 34,927,790 | |
| Shares (Diluted) | 63,374,183 | 58,851,021 | -105,411,418 | 56,993,841 | 49,726,823 | 48,889,058 | -94,422,655 | 47,782,619 | 47,235,080 | 46,927,550 | -75,996,436 | 41,098,920 | 38,107,334 | 37,675,306 | -64,420,691 | 34,927,790 | |
| EBITDA | $-43M | $-783M | · | $3M | $-5M | $-9M | · | $-13M | $-24M | $-21M | · | $-25M | $-24M | $-26M | · | $-33M |
Balance general 23
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $331M | $325M | $297M | $282M | $228M | $212M | $223M | $223M | $233M | $303M | · | $303M | $297M | $49M | · | $36M | |
| Short-term Investments | $108M | $61M | $87M | $94M | $76M | $66M | $58M | $61M | $45M | · | · | $3M | $33M | $83M | · | $150M | |
| Receivables | $145M | $133M | $123M | $107M | $107M | $96M | $78M | $69M | $60M | $55M | · | $48M | $35M | $25M | · | $16M | |
| Inventory | $26M | $26M | $25M | $24M | $23M | $22M | $22M | $22M | $20M | $22M | · | $22M | $9M | $7M | · | $7M | |
| Prepaid Expense | $27M | $25M | $18M | $24M | $19M | $15M | $12M | $12M | $9M | $10M | · | $12M | $10M | $9M | · | $7M | |
| Current Assets | $636M | $569M | $550M | $531M | $453M | $411M | $393M | $387M | $368M | $389M | · | $389M | $384M | $172M | · | $216M | |
| PP&E (Net) | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $1M | $1M | $501.0K | · | $787.0K | $866.0K | $877.0K | · | $795.0K | |
| Accum. Depreciation | · | · | $1M | · | · | · | $700.0K | · | · | · | · | · | · | · | · | · | |
| Intangibles | $247M | $254M | $261M | $232M | $238M | $244M | $250M | $256M | $262M | $257M | · | $258M | $56M | $58M | · | $45M | |
| Other Non-current Assets | $22M | $16M | $12M | $10M | $7M | $5M | $5M | $5M | $4M | $4M | · | $2M | $1M | $1M | · | $2M | |
| Total Assets | $1.04B | $891M | $843M | $785M | $726M | $690M | $671M | $668M | $661M | $652M | · | $651M | $444M | $334M | · | $364M | |
| Accounts Payable | $23M | $59M | $10M | $12M | $18M | $12M | $15M | $10M | $10M | $16M | · | $7M | $14M | $6M | · | $11M | |
| Accrued Liabilities | · | · | $196M | · | · | · | $112M | $105M | $101M | $90M | · | $66M | $43M | $40M | · | $38M | |
| Current Liabilities | $223M | $273M | $206M | $160M | $145M | $128M | $127M | $116M | $112M | $106M | · | $75M | $58M | $49M | · | $51M | |
| Capital Leases | $10M | $11M | $8M | $7M | $8M | $7M | $8M | $8M | $8M | $328.0K | · | $868.0K | $1M | $1M | · | $1M | |
| Other Non-current Liabilities | $11M | $6M | $5M | $16M | $9M | $14M | $3M | $4M | $4M | $4M | · | $7.0K | $10.0K | $772.0K | · | $4M | |
| Total Liabilities | $1.06B | $648M | $528M | $493M | $471M | $457M | $445M | $436M | $432M | $417M | · | $382M | $365M | $192M | · | $195M | |
| Common Stock | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | · | $5.0K | $4.0K | $4.0K | · | $4.0K | |
| Retained Earnings | $-1.52B | $-1.46B | $-668M | $-662M | $-665M | $-659M | $-644M | $-620M | $-606M | $-582M | · | $-521M | $-497M | $-423M | · | $-356M | |
| AOCI | $-674.0K | $-28.0K | $351.0K | $37.0K | $352.0K | $-258.0K | $-373.0K | $920.0K | $-477.0K | $-13.0K | · | $-1M | $76.0K | $136.0K | · | $-413.0K | |
| Stockholders' Equity | $-10M | $242M | $315M | $292M | $255M | $233M | $226M | $232M | $229M | $235M | $249M | $269M | $79M | $141M | $142M | $169M | |
| Liabilities + Equity | $1.04B | $891M | $843M | $785M | $726M | $690M | $671M | $668M | $661M | $652M | · | $651M | $444M | $334M | · | $364M | |
| Shares Outstanding | 64,754,699 | 60,926,165 | 51,896,391 | 51,314,176 | 50,058,392 | 49,451,223 | 48,338,096 | 47,968,121 | 47,571,847 | 47,061,106 | · | 46,595,745 | 38,222,058 | 38,012,247 | · | 36,813,754 |
Flujo de Efectivo 13
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $7M | $7M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $5M | $3M | $1M | $1M | $1M | $1M | |
| Stock-based Comp | $31M | $36M | $19M | $18M | $18M | $16M | $13M | $12M | $12M | $11M | $10M | $8M | $8M | $9M | $7M | $7M | |
| Amort. of Intangibles | $7M | $7M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $5M | $3M | $1M | $1M | $1M | $1M | |
| Other Non-cash | · | $518M | · | · | · | $-9M | · | · | · | $23M | · | · | · | $-14M | · | · | |
| Operating Cash Flow | $-44M | $-229M | $6M | $40M | $12M | $-2M | $-5M | $4M | $-4M | $15M | $-17M | $-18M | $-2M | $-19M | $-34M | $-26M | |
| CapEx | $23.0K | $664.0K | $600.0K | $187.0K | $126.0K | $41.0K | $20.0K | $181.0K | $779.0K | $13.0K | $0 | $0 | $68.0K | $41.0K | $242.0K | $19.0K | |
| Investing Cash Flow | $-160M | $-12M | $1M | $-2M | $-7M | $-16M | $641.0K | $-18M | $-73M | $-13.0K | $-2M | $-183M | $36M | $27M | $27M | $-80M | |
| Stock Issued | · | · | · | · | · | · | $0 | $0 | $0 | $0 | $0 | $0 | $0 | $14M | $0 | $0 | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $0 | · | · | · | $14M | · | · | |
| Financing Cash Flow | $211M | $270M | $9M | $16M | $9M | $6M | $5M | $4M | $7M | $1M | $2M | $207M | $115M | $13M | $-329.0K | $86M | |
| Net Change in Cash | $6M | $28M | $16M | $54M | $16M | $-11M | $-466.0K | $-10M | $-69M | $17M | $-17M | $6M | $148M | $21M | $-8M | $-20M | |
| Taxes Paid | $907.0K | $220.0K | $6.0K | $504.0K | $1M | $162.0K | $233.0K | $432.0K | $200.0K | $139.0K | $125.0K | $0 | $0 | $0 | · | · | |
| Free Cash Flow | · | $-229M | · | · | · | $-2M | · | · | · | $15M | · | · | · | $-34M | · | · |
Rentabilidad 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -24.1% | -493.8% | · | 2.0% | -3.9% | -13.6% | · | -14.0% | -31.1% | -38.2% | · | -52.7% | -64.7% | -85.9% | · | -175.1% | |
| Net Margin | -38.1% | -494.2% | · | 2.2% | -4.6% | -13.2% | · | -15.8% | -31.6% | -36.5% | · | -49.4% | -197.4% | -95.3% | · | -190.1% | |
| Pretax Margin | -37.2% | -493.9% | · | 2.0% | -4.3% | -12.2% | · | -15.4% | -30.8% | -35.6% | · | -48.9% | -196.6% | -94.7% | · | -190.1% | |
| EBITDA Margin | -24.1% | -489.5% | · | 2.0% | -3.9% | -8.2% | · | -14.0% | -31.1% | -30.0% | · | -52.7% | -64.7% | -81.7% | · | -175.1% | |
| ROA | -7.6% | -100.0% | · | 0.40% | -0.85% | -2.2% | · | -2.2% | -4.5% | -5.1% | · | -4.7% | -20.0% | -9.8% | · | -11.9% | |
| ROE | -54.9% | -332.2% | · | 1.1% | -2.4% | -6.3% | · | -5.7% | -16.0% | -13.5% | · | -10.8% | -78.2% | -24.1% | · | -31.6% | |
| ROIC | 418.7% | -325.8% | · | 0.98% | -2.1% | -7.0% | · | -5.6% | -10.9% | -11.6% | · | -9.4% | -31.0% | -19.4% | · | -19.4% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.9 | 2.1 | · | 3.3 | 3.1 | 3.2 | · | 3.3 | 3.3 | 3.7 | · | 5.2 | 6.6 | 3.5 | · | 4.2 | |
| Quick Ratio | 2.6 | 1.9 | · | 3.0 | 2.8 | 2.9 | · | 3.0 | 3.0 | 3.4 | · | 4.7 | 6.3 | 3.2 | · | 3.9 |
Eficiencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.2 | 0.2 | · | 0.2 | 0.2 | 0.2 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | 0.1 | 0.1 | · | 0.1 | |
| Receivables Turnover | 1.4 | 1.4 | · | 1.5 | 1.5 | 1.5 | · | 1.6 | 1.6 | 1.7 | · | 1.5 | 1.5 | 1.9 | · | 2.3 |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $597M | $532M | · | $463M | $408M | $349M | · | $285M | $232M | $186M | · | $136M | $105M | $81M | · | $54M | |
| Net Income TTM | $-860M | $-808M | · | $-32M | $-59M | $-79M | · | $-88M | $-148M | $-153M | · | $-163M | $-167M | $-129M | · | $-146M | |
| Market Cap | $7.58B | $5.63B | · | $3.76B | $2.55B | $2.23B | · | $1.87B | $1.63B | $1.18B | · | $1.47B | $989M | $913M | · | $773M | |
| P/E | -8.0 | -6.7 | · | -109.4 | -41.0 | -27.1 | · | -20.2 | -9.6 | -6.5 | · | -7.3 | -5.6 | -6.3 | · | -4.6 | |
| P/S | 12.7 | 10.6 | · | 8.1 | 6.2 | 6.4 | · | 6.6 | 7.0 | 6.4 | · | 10.9 | 9.4 | 11.3 | · | 14.3 | |
| P/B | -727.4 | 23.2 | · | 12.9 | 10.0 | 9.6 | · | 8.1 | 7.1 | 5.0 | · | 5.5 | 12.6 | 6.5 | · | 4.6 | |
| P / Tangible Book | · | · | · | 62.5 | 147.4 | · | · | · | · | · | · | 137.1 | 44.6 | 10.9 | · | 6.2 | |
| P / Cash Flow | · | -24.6 | · | · | · | -1136.0 | · | · | · | 77.7 | · | · | · | -27.0 | · | · | |
| P / FCF | · | -24.5 | · | · | · | -1112.8 | · | · | · | 77.8 | · | · | · | -27.0 | · | · | |
| Earnings Yield | -12.4% | -14.9% | · | -0.91% | -2.4% | -3.7% | · | -5.0% | -10.4% | -15.3% | · | -13.7% | -17.8% | -16.0% | · | -21.8% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $521M | $337M | $186M | $77M | $19M |
| Margen Operativo % | -4.2% | -26.0% | -58.6% | -170.3% | -906.1% |
| Beneficio neto | $-23M | $-88M | $-163M | $-136M | $-84M |
| EPS Diluido | $-0.47 | $-1.85 | $-4.00 | $-4.02 | $-2.77 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 2.7 | 3.1 | 4.5 | 2.9 | 3.9 |
| Ratio Rápido | 2.5 | 2.8 | 4.1 | 2.7 | 3.8 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $55M | $9M | $-71M | $-120M | $-133M |
Últimas noticias Noticias recientes que mencionan a esta empresa
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Propietarios institucionales (13F) 349 declarantes · $6.6B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 63 (-10 vs trimestre anterior) | 41 (+11 vs trimestre anterior) | 119 (+2 vs trimestre anterior) | 102 (+19 vs trimestre anterior) | -4.0M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| Frazier Life Sciences Management, L.P. | $899 060 606 | 7 679 684 | 13,65% | Acciones |
| JANUS HENDERSON GROUP PLC | $626 019 056 | 6 775 388 | 9,51% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $278 277 614 | 2 377 019 | 4,23% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $263 888 541 | 2 254 109 | 4,01% | Acciones |
| STATE STREET CORP | $254 122 561 | 2 170 689 | 3,86% | Acciones |
| FMR LLC | $247 478 839 | 2 113 939 | 3,76% | Acciones |
| VANGUARD GROUP INC | $177 282 549 | 2 244 367 | 2,69% | Acciones |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | $164 453 029 | 1 404 741 | 2,50% | Acciones |
| EVENTIDE ASSET MANAGEMENT, LLC | $146 202 247 | 1 248 389 | 2,22% | Acciones |
| TANG CAPITAL MANAGEMENT LLC | $144 701 681 | 1 236 027 | 2,20% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $142 515 401 | 1 217 103 | 2,16% | Acciones |
| Capital World Investors | $135 037 904 | 1 153 480 | 2,05% | Acciones |
| NOVO HOLDINGS A/S | $131 703 750 | 1 125 000 | 2,00% | Acciones |
| TCG Crossover Management, LLC | $124 334 076 | 1 062 049 | 1,89% | Acciones |
| BVF INC/IL | $123 629 081 | 1 056 027 | 1,88% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $106 638 009 | 910 891 | 1,62% | Acciones |
| Polar Capital Holdings Plc | $98 985 495 | 845 524 | 1,50% | Acciones |
| Rock Springs Capital Management LP | $93 438 835 | 798 145 | 1,42% | Acciones |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $88 042 000 | 752 044 | 1,34% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $80 815 528 | 690 318 | 1,23% | Acciones |
| Clearbridge Investments, LLC | $74 893 623 | 639 734 | 1,14% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $70 994 409 | 606 427 | 1,08% | Acciones |
| Woodline Partners LP | $66 483 351 | 567 894 | 1,01% | Acciones |
| Pictet Asset Management Holding SA | $61 630 682 | 526 443 | 0,94% | Acciones |
| Balyasny Asset Management L.P. | $57 267 132 | 489 170 | 0,87% | Acciones |
| EMERALD ADVISERS, LLC | $54 823 296 | 468 295 | 0,83% | Acciones |
| GOLDMAN SACHS GROUP INC | $54 346 587 | 464 223 | 0,83% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $52 614 653 | 449 429 | 0,80% | Acciones |
| BAKER BROS. ADVISORS LP | $52 210 293 | 445 975 | 0,79% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $51 766 598 | 442 185 | 0,79% | Acciones |
| AMERIPRISE FINANCIAL INC | $51 255 634 | 437 818 | 0,78% | Acciones |
| NEXT CENTURY GROWTH INVESTORS LLC | $49 194 335 | 420 213 | 0,75% | Acciones |
| Connor, Clark & Lunn Investment Management Ltd. | $49 176 775 | 420 063 | 0,75% | Acciones |
| BOONE CAPITAL MANAGEMENT LLC | $48 659 092 | 415 641 | 0,74% | Acciones |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $44 572 061 | 380 730 | 0,68% | Acciones |
| Candriam S.C.A. | $43 992 694 | 376 143 | 0,67% | Acciones |
| LOOMIS SAYLES & CO L P | $43 189 230 | 368 918 | 0,66% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $40 974 500 | 350 000 | 0,62% | Acciones |
| Palo Alto Investors LP | $40 834 953 | 348 808 | 0,62% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $40 767 286 | 348 230 | 0,62% | Acciones |
| Octagon Capital Advisors LP | $39 675 023 | 338 900 | 0,60% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $39 506 559 | 337 461 | 0,60% | Acciones |
| BANK OF AMERICA CORP /DE/ | $39 300 282 | 335 699 | 0,60% | Acciones |
| RA CAPITAL MANAGEMENT, L.P. | $37 293 117 | 318 554 | 0,57% | Acciones |
| Hood River Capital Management LLC | $35 874 814 | 306 439 | 0,54% | Acciones |
| Penn Capital Management Company, LLC | $35 055 617 | 298 914 | 0,53% | Acciones |
| TimesSquare Capital Management, LLC | $34 778 576 | 376 473 | 0,53% | Acciones |
| EMERALD MUTUAL FUND ADVISERS TRUST | $33 876 780 | 289 372 | 0,51% | Acciones |
| Patient Square Capital LP | $30 496 735 | 260 500 | 0,46% | Acciones |
| MORGAN STANLEY | $30 180 880 | 257 802 | 0,46% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $29 332 825 | 250 558 | 0,45% | Acciones |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $28 796 644 | 245 978 | 0,44% | Acciones |
| NAN FUNG TRINITY (HK) LTD | $27 239 731 | 232 679 | 0,41% | Acciones |
| Trails Edge Capital Partners, LP | $26 143 136 | 223 312 | 0,40% | Acciones |
| First Turn Management, LLC | $25 527 231 | 218 051 | 0,39% | Acciones |
| Erste Asset Management GmbH | $25 215 000 | 205 000 | 0,38% | Acciones |
| SEGALL BRYANT & HAMILL, LLC | $20 953 189 | 178 980 | 0,32% | Acciones |
| Ensign Peak Advisors, Inc | $20 557 258 | 175 598 | 0,31% | Acciones |
| Nicholas Investment Partners, LP | $20 217 404 | 172 695 | 0,31% | Acciones |
| CITIGROUP INC | $19 011 700 | 162 396 | 0,29% | Acciones |
| AXA Investment Managers S.A. | $18 744 487 | 255 688 | 0,28% | Acciones |
| TWO SIGMA ADVISERS, LP | $18 333 579 | 232 100 | 0,28% | Acciones |
| Rhenman & Partners Asset Management AB | $16 296 729 | 139 205 | 0,25% | Acciones |
| FIRST TRUST ADVISORS LP | $15 938 026 | 136 141 | 0,24% | Acciones |
| Highlander Partners, L.P. | $14 397 269 | 122 980 | 0,22% | Acciones |
| PDT Partners, LLC | $14 287 340 | 122 041 | 0,22% | Acciones |
| PERCEPTIVE ADVISORS LLC | $13 508 824 | 115 391 | 0,21% | Acciones |
| RICE HALL JAMES & ASSOCIATES, LLC | $12 956 488 | 110 673 | 0,20% | Acciones |
| Seven Fleet Capital Management LP | $12 923 709 | 110 393 | 0,20% | Acciones |
| ESSEX INVESTMENT MANAGEMENT CO LLC | $12 370 670 | 105 669 | 0,19% | Acciones |
| RAYMOND JAMES FINANCIAL INC | $12 130 910 | 103 621 | 0,18% | Acciones |
| Capricorn Fund Managers Ltd | $11 852 167 | 101 240 | 0,18% | Acciones |
| Atle Fund Management AB | $11 801 475 | 100 807 | 0,18% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $11 263 656 | 96 213 | 0,17% | Acciones |
| NEUBERGER BERMAN GROUP LLC | $10 885 871 | 92 986 | 0,17% | Acciones |
| Cubist Systematic Strategies, LLC | $10 570 103 | 144 184 | 0,16% | Acciones |
| PEREGRINE CAPITAL MANAGEMENT LLC | $10 398 157 | 88 820 | 0,16% | Acciones |
| Swiss National Bank | $9 927 536 | 84 800 | 0,15% | Acciones |
| BlackRock, Inc. | $9 709 786 | 82 940 | 0,15% | Acciones |
| Voleon Capital Management LP | $9 702 410 | 82 877 | 0,15% | Acciones |
| Fisher Asset Management, LLC | $9 655 464 | 82 476 | 0,15% | Acciones |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | $9 046 935 | 77 278 | 0,14% | Acciones |
| Soleus Capital Management, L.P. | $8 780 250 | 75 000 | 0,13% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $8 750 983 | 74 750 | 0,13% | Acciones |
| Alyeska Investment Group, L.P. | $8 658 380 | 73 959 | 0,13% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $7 902 225 | 67 500 | 0,12% | Opción de compra |
| ARISTEIA CAPITAL, L.L.C. | $7 548 088 | 64 475 | 0,11% | Acciones |
| Lisanti Capital Growth, LLC | $7 409 946 | 63 295 | 0,11% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $7 124 997 | 60 861 | 0,11% | Acciones |
| RHUMBLINE ADVISERS | $6 951 601 | 59 380 | 0,11% | Acciones |
| Hillsdale Investment Management Inc. | $6 863 814 | 58 630 | 0,10% | Acciones |
| Legato Capital Management LLC | $6 849 999 | 58 512 | 0,10% | Acciones |
| BARCLAYS PLC | $6 522 555 | 55 715 | 0,10% | Acciones |
| Trexquant Investment LP | $6 245 567 | 53 349 | 0,09% | Acciones |
| F/m Investments LLC | $6 027 115 | 51 483 | 0,09% | Acciones |
| PICTON MAHONEY ASSET MANAGEMENT | $5 581 782 | 47 679 | 0,08% | Acciones |
| Secure Asset Management, LLC | $5 514 524 | 47 105 | 0,08% | Acciones |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $5 468 692 | 46 713 | 0,08% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $5 430 743 | 58 787 | 0,08% | Acciones |
| Informed Momentum Co LLC | $5 017 620 | 42 860 | 0,08% | Acciones |
Informantes de la empresa 33 insiders · 7 directivos · 11 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Ian Clements | Chief Financial Officer | 10 de noviembre de 2022 A | 30 011 | 0 | 0 | $0 |
| Peter Radovich | PRESIDENT AND COO | 5 de junio de 2026 M | 57 260 | 0 | 0 | $0 |
| Jolanda Howe | SVP, GLOBAL CONTROLLER | 18 de agosto de 2026 M | 1 274 | 0 | 4 | $-4 784 712 |
| Joanne Quan | CHIEF MEDICAL OFFICER | 21 de enero de 2025 A | 5 649 | 0 | 0 | $0 |
| Pamela Vig | CHIEF SCIENTIFIC OFFICER | 24 de junio de 2024 M | 27 406 | 0 | 0 | $0 |
| Lara Longpre | CHIEF DEVELOPMENT OFFICER | 9 de enero de 2023 S | 104 369 | 0 | 0 | $0 |
| Edwin Jonathan Tucker | Chief Medical Officer | 10 de noviembre de 2021 A | 45 838 | 0 | 0 | $0 |
| Lon Cardon | Consejero | 15 de junio de 2026 A | 9 680 | 0 | 0 | $0 |
| William Fairey | Consejero | 15 de junio de 2026 A | 2 500 | 0 | 0 | $0 |
| Saira Ramasastry | Consejero | 15 de junio de 2026 A | 0 | 0 | 1 | $-397 700 |
| Laurent Fischer | Consejero | 15 de junio de 2026 A | 10 727 | 0 | 0 | $0 |
| Laura Brege | Consejero | 15 de junio de 2026 A | 15 703 | 0 | 2 | $-1 264 868 |
| Patrick J. Heron | Consejero | 15 de junio de 2026 A | 459 010 | 1 | 0 | $8 999 984 |
| Timothy P Walbert | Consejero | 15 de junio de 2026 A | 9 680 | 0 | 0 | $0 |
| Michael G Grey | Consejero | 15 de junio de 2026 A | 0 | 0 | 3 | $-11 100 000 |
| Niall O'Donnell, Ph.D. | Consejero | 15 de noviembre de 2022 S | 1 621 118 | 0 | 0 | $0 |
| Carol L Brosgart | Consejero | 2 de junio de 2022 A | — | 0 | 0 | $0 |
| Edward T. Mathers | Consejero | 2 de junio de 2022 A | — | 0 | 0 | $0 |
| Carmen Chang | Propietario del 10% | 13 de junio de 2023 J | 135 | 0 | 0 | $0 |
| New Enterprise Associates 16, L.P. | Propietario del 10% | 13 de junio de 2023 J | 2 186 243 | 0 | 0 | $0 |
| Mohamad Makhzoumi | Propietario del 10% | 13 de junio de 2023 J | 11 348 | 0 | 0 | $0 |
| Ali Behbahani | Propietario del 10% | 13 de junio de 2023 J | 135 | 0 | 0 | $0 |
| Anthony A. Florence, Jr. | Propietario del 10% | 13 de junio de 2023 J | 11 348 | 0 | 0 | $0 |
| Paul Walker | Propietario del 10% | 13 de junio de 2023 J | 114 | 0 | 0 | $0 |
| Forest Baskett | Propietario del 10% | 13 de junio de 2023 J | 1 548 | 0 | 0 | $0 |
| Scott D. Sandell | Propietario del 10% | 13 de junio de 2023 J | 11 348 | 0 | 0 | $0 |
| Peter W. Sonsini | Propietario del 10% | 22 de julio de 2019 C | 4 186 243 | 0 | 0 | $0 |
| Novo Holdings A/S | Propietario del 10% | 22 de julio de 2019 C | 2 445 147 | 0 | 0 | $0 |
| Joshua Makower | Propietario del 10% | 22 de julio de 2019 C | 4 186 243 | 0 | 0 | $0 |
| David M Mott | Propietario del 10% | 22 de julio de 2019 C | 4 186 243 | 0 | 0 | $0 |
| Peter J Barris | Propietario del 10% | 22 de julio de 2019 C | 4 186 243 | 0 | 0 | $0 |
| Eric Bjerkholt | — | 11 de agosto de 2026 S | 36 355 | 0 | 12 | $-3 312 043 |
| Christopher Peetz | — | 10 de agosto de 2026 M | 194 309 | 0 | 8 | $-4 670 036 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 7 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| Frazier Life Sciences IX, L.P., FHMLS IX, L.P., FHMLS IX, L.L.C., Frazier Life Sciences X, L.P., FHMLS X, L.P., FHMLS X, L.L.C., Frazier Life Sciences Public Fund, L.P., FHMLSP, L.P., FHMLSP, L.L.C., Frazier Life Sciences XI, L.P., FHMLS XI, L.P., FHMLS XI, L.L.C., Frazier Life Sciences XII, L.P., FHMLS XII, L.P., FHMLS XII, L.L.C., James N. Topper, Patrick J. Heron ×9 presentaciones | 27 de enero de 2026 | 6,80% | Enmienda | Inversión pasiva | SEC |
| 29 de diciembre de 2023 | — | Presentación inicial | — | SEC | |
| New Enterprise Associates 16, L.P., NEA Partners 16, L.P., NEA 16 GP, LLC, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad H. Makhzoumi, Scott D. Sandell, Paul Walker ×2 presentaciones | 23 de junio de 2023 | — | Presentación inicial | — | SEC |
| Persona informante no revelada, Persona informante no revelada, Persona informante no revelada | 1 de diciembre de 2022 | — | Presentación inicial | — | SEC |
| Novo Holdings A/S ×7 presentaciones | 18 de agosto de 2022 | — | Presentación inicial | — | SEC |
| Persona informante no revelada, Persona informante no revelada, Persona informante no revelada | 22 de diciembre de 2020 | — | Presentación inicial | — | SEC |
| Persona informante no revelada, Persona informante no revelada, Persona informante no revelada | 1 de agosto de 2019 | — | Presentación inicial | Inversión pasiva | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 58 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| LFSC · RBB Fund, Inc. | 4,92% | 50 911 NS | 31 de mayo de 2026 | N-PORT |
| SBIO · ALPS ETF Trust | 3,90% | 62 199 NS | 31 de mayo de 2026 | N-PORT |
| BBP · ETFis Series Trust I | 2,39% | 14 558 NS | 30 de abril de 2026 | N-PORT |
| FSCC · Federated Hermes ETF Trust | 1,15% | 31 245 NS | 31 de mayo de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,99% | 52 917 NS | 30 de abril de 2026 | N-PORT |
| ILDR · First Trust Exchange-Traded Fund VI… | 0,98% | 27 829 NS | 31 de mayo de 2026 | N-PORT |
| FNY · First Trust Exchange-Traded AlphaDE… | 0,70% | 37 112 NS | 30 de abril de 2026 | N-PORT |
| FTXH · First Trust Exchange-Traded Fund VI | 0,59% | 1 840 NS | 30 de junio de 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 0,54% | 2 191 NS | 31 de mayo de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,38% | 3 585 SH | 21 de agosto de 2026 | Diario |
| ESSC · Strategy Shares | 0,37% | 979 NS | 30 de abril de 2026 | N-PORT |
| FNX · First Trust Exchange-Traded AlphaDE… | 0,36% | 49 242 NS | 30 de abril de 2026 | N-PORT |
| IBB · iShares Trust | 0,34% | 370 464 SH | 21 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,33% | 50 804 SH | 19 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,31% | 2 231 NS | 31 de mayo de 2026 | N-PORT |
| PSC · Principal Exchange-Traded Funds | 0,30% | 60 377 NS | 30 de junio de 2026 | N-PORT |
| OASC · Unified Series Trust | 0,29% | 2 396 NS | 31 de mayo de 2026 | N-PORT |
| IWO · iShares Trust | 0,29% | 441 449 SH | 21 de agosto de 2026 | Diario |
| AFSM · First Trust Exchange-Traded Fund VI… | 0,26% | 2 555 NS | 31 de mayo de 2026 | N-PORT |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,25% | 19 108 NS | 30 de abril de 2026 | N-PORT |
| FAD · First Trust Exchange-Traded AlphaDE… | 0,21% | 10 203 NS | 30 de abril de 2026 | N-PORT |
| ROSC · Lattice Strategies Trust | 0,20% | 1 131 NS | 30 de abril de 2026 | N-PORT |
| BKSE · BNY Mellon ETF Trust | 0,19% | 1 598 NS | 30 de abril de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,19% | 18 177 NS | 31 de mayo de 2026 | N-PORT |
| VBK · VANGUARD INDEX FUNDS | 0,17% | 686 321 SH | 19 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,17% | 273 231 SH | 19 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,15% | 1 209 046 SH | 21 de agosto de 2026 | Diario |
| ISCG · iShares Trust | 0,14% | 13 979 SH | 21 de agosto de 2026 | Diario |
| FSMD · FIDELITY COVINGTON TRUST | 0,13% | 31 277 NS | 30 de abril de 2026 | N-PORT |
| RSSL · Global X Funds | 0,12% | 18 274 NS | 30 de abril de 2026 | N-PORT |
| RB · ProShares Trust | 0,11% | 13 NS | 31 de mayo de 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,11% | 18 506 SH | 19 de agosto de 2026 | Diario |
| ITWO · ProShares Trust | 0,11% | 1 985 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,10% | 227 202 NS | 31 de mayo de 2026 | N-PORT |
| VB · VANGUARD INDEX FUNDS | 0,07% | 1 188 816 SH | 19 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,07% | 126 877 SH | 19 de agosto de 2026 | Diario |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,07% | 2 008 SH | 21 de agosto de 2026 | Diario |
| ISCB · iShares Trust | 0,07% | 1 994 SH | 21 de agosto de 2026 | Diario |
| AVIE · AMERICAN CENTURY ETF TRUST | 0,06% | 65 NS | 31 de mayo de 2026 | N-PORT |
| UWM · ProShares Trust | 0,06% | 1 553 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,06% | 552 499 SH | 19 de agosto de 2026 | Diario |
| FHLC · FIDELITY COVINGTON TRUST | 0,06% | 17 493 NS | 30 de abril de 2026 | N-PORT |
| ESML · iShares Trust | 0,05% | 13 978 SH | 21 de agosto de 2026 | Diario |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,05% | 13 366 SH | 21 de agosto de 2026 | Diario |
| URTY · ProShares Trust | 0,05% | 1 572 NS | 31 de mayo de 2026 | N-PORT |
| WSML · iShares Trust | 0,04% | 2 581 SH | 21 de agosto de 2026 | Diario |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,02% | 1 589 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,02% | 39 NS | 31 de mayo de 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 14 006 NS | 31 de mayo de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,01% | 1 648 584 SH | 19 de agosto de 2026 | Diario |