TRDA Entrada Therapeutics, Inc. - Common Stock
TRDA Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
TRDA Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
TRDA Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 5 35,7%
- Compra 7 50,0%
- Mantener 2 14,3%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
4 analistas · 2026-08-15Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-1.01 | $-1.07 | 0.06% |
| 31 de marzo de 2026 | $-0.95 | $-1.06 | 0.11% |
| 31 de diciembre de 2025 | $-0.94 | $-1.17 | 0.23% |
| 30 de septiembre de 2025 | $-1.06 | $-0.96 | -0.10% |
| 30 de junio de 2025 | $-1.04 | $-0.86 | -0.18% |
| 31 de marzo de 2025 | $-0.42 | $-0.80 | 0.38% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| TRDA | $394M | -3.0 | -87.9% | -565.5% | -41.9% | — |
| AVXL | $771M | -16.5 | -36.1% | -991.4% | -47.7% | — |
| ELDN | $114M | -2.9 | — | — | -69.4% | — |
| MYGN | $575M | -1.6 | -1.6% | -44.4% | -96.8% | 69.9% |
| ANIK | $133M | -12.6 | -5.9% | -9.6% | -7.5% | 56.6% |
| RNAC | $188M | -1.4 | -92.8% | -4658.6% | 202.4% | — |
| SRZN | — | — | — | — | — | — |
| SION | $1.84B | -21.9 | — | — | -23.4% | — |
| ZSQR | — | — | — | — | — | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 13
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue | $25M | $211M | $129M | |
| R&D Expense | $142M | $125M | $100M | |
| SG&A Expense | $41M | $38M | $32M | |
| Operating Expenses | $183M | $164M | $132M | |
| Operating Income | $-158M | $47M | $-3M | |
| Other Non-op | $15M | $19M | $15M | |
| Income Tax | $924.0K | $859.0K | $19M | |
| Net Income | $-144M | $66M | $-7M | |
| EPS (Basic) | $-3.47 | $1.76 | $-0.20 | |
| EPS (Diluted) | $-3.47 | $1.68 | $-0.20 | |
| Shares (Basic) | 41,371,486 | 37,306,363 | 33,050,319 | |
| Shares (Diluted) | 41,371,486 | 39,003,169 | 33,050,319 | |
| EBITDA | $-158M | $47M | $-3M |
Balance general 20
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Cash & Equivalents | $90M | $101M | $68M | |
| Prepaid Expense | $9M | $16M | $12M | |
| Current Assets | $306M | $440M | $370M | |
| PP&E (Net) | $7M | $11M | $11M | |
| PP&E (Gross) | $17M | $20M | $17M | |
| Accum. Depreciation | $10M | $9M | $6M | |
| Other Non-current Assets | $70.0K | $284.0K | $3M | |
| Total Assets | $377M | $526M | $469M | |
| Accounts Payable | $2M | $4M | $3M | |
| Accrued Liabilities | $18M | $13M | $11M | |
| Current Liabilities | $24M | $39M | $159M | |
| Capital Leases | $47M | $52M | $60M | |
| Total Liabilities | $71M | $98M | $227M | |
| Common Stock | $4.0K | $4.0K | $3.0K | |
| Paid-in Capital | $579M | $558M | $437M | |
| Retained Earnings | $-273M | $-129M | $-195M | |
| AOCI | $652.0K | $-43.0K | $195.0K | |
| Stockholders' Equity | $306M | $429M | $242M | |
| Liabilities + Equity | $377M | $526M | $469M | |
| Shares Outstanding | 38,284,221 | 37,574,538 | 33,437,296 |
Flujo de Efectivo 9
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Stock-based Comp | $20M | $18M | $13M | |
| Deferred Tax | $0 | $0 | $0 | |
| Operating Cash Flow | $-129M | $-42M | $140M | |
| CapEx | $1M | $3M | $6M | |
| Investing Cash Flow | $117M | $-28M | $-138M | |
| Financing Cash Flow | $887.0K | $103M | $21M | |
| Net Change in Cash | $-11M | $34M | $22M | |
| Taxes Paid | $2M | $5M | $15M | |
| Free Cash Flow | $-130M | $-45M | $134M |
Rentabilidad 5
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Operating Margin | -621.1% | 22.3% | -2.5% | |
| Net Margin | -565.5% | 31.1% | -5.2% | |
| EBITDA Margin | -621.1% | 22.3% | -2.5% | |
| ROA | -31.8% | 13.2% | -1.8% | |
| ROE | -41.9% | 15.4% | -2.7% |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Current Ratio | 12.5 | 11.1 | 2.3 | |
| Quick Ratio | 3.7 | 2.6 | 0.4 |
Eficiencia 1
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Asset Turnover | 0.1 | 0.4 | 0.4 |
Tasas de Crecimiento 1
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue YoY | -87.9% | 63.4% | · |
Valoración (TTM) 10
| Métrica | Tendencia | 2025 | 2024 | 2023 |
|---|---|---|---|---|
| Revenue TTM | $25M | $211M | $129M | |
| Net Income TTM | $-144M | $66M | $-7M | |
| Market Cap | $394M | $650M | $505M | |
| P/E | -3.0 | 10.3 | -75.5 | |
| P/S | 15.5 | 3.1 | 3.9 | |
| P/B | 1.3 | 1.5 | 2.1 | |
| P / Tangible Book | 1.3 | 1.5 | 2.1 | |
| P / Cash Flow | -3.1 | -15.6 | 3.6 | |
| P / FCF | -3.0 | -14.5 | 3.8 | |
| Earnings Yield | -33.8% | 9.7% | -1.3% |
Estado de resultados 13
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | $898.0K | $875.0K | $1M | $2M | $2M | $21M | $37M | $20M | $95M | $59M | $42M | $44M | $18M | $25M | · | $0 | |
| R&D Expense | $35M | $33M | $34M | $38M | $38M | $32M | $33M | $31M | $32M | $29M | $28M | $22M | $26M | $23M | $16M | $19M | |
| SG&A Expense | $10M | $10M | $10M | $10M | $11M | $10M | $10M | $10M | $9M | $9M | $9M | $8M | $8M | $8M | $10M | $7M | |
| Operating Expenses | $46M | $43M | $44M | $49M | $49M | $42M | $43M | $41M | $41M | $38M | $37M | $30M | $34M | $31M | $26M | $26M | |
| Operating Income | $-45M | $-42M | $-42M | $-47M | $-47M | $-22M | $-6M | $-22M | $53M | $21M | $5M | $14M | $-16M | $-6M | $-26M | $-26M | |
| Other Non-op | $2M | $3M | $3M | $4M | $4M | $4M | $5M | $6M | $4M | $4M | $4M | $4M | $4M | $3M | $950.0K | $799.0K | |
| Income Tax | $35.0K | $38.0K | $92.0K | $654.0K | $178.0K | $0 | $-2M | $-2M | $3M | $2M | $19M | $-17M | $14M | $4M | $0 | $0 | |
| Net Income | $-43M | $-40M | $-39M | $-44M | $-43M | $-17M | $1M | $-14M | $55M | $23M | $-10M | $35M | $-26M | $-7M | $-25M | $-25M | |
| EPS (Basic) | $-1.01 | $-0.95 | $-0.95 | $-1.06 | $-1.04 | $-0.42 | $-0.20 | $-0.35 | $1.61 | $0.70 | $-0.28 | $1.07 | $-0.78 | $-0.21 | $-0.79 | $-0.80 | |
| EPS (Diluted) | $-1.01 | $-0.95 | $-0.95 | $-1.06 | $-1.04 | $-0.42 | $-0.20 | $-0.35 | $1.55 | $0.68 | $-0.23 | $1.02 | $-0.78 | $-0.21 | $-0.79 | $-0.80 | |
| Shares (Basic) | 42,221,665 | 41,836,275 | -82,503,565 | 41,462,567 | 41,338,752 | 41,073,732 | -71,000,860 | 40,629,602 | 34,180,549 | 33,497,072 | -65,768,587 | 33,281,287 | 33,163,320 | 32,374,299 | -62,526,962 | 31,298,052 | |
| Shares (Diluted) | 42,221,665 | 41,836,275 | -82,503,565 | 41,462,567 | 41,338,752 | 41,073,732 | -71,924,387 | 40,629,602 | 35,507,029 | 34,790,925 | -67,262,751 | 34,775,451 | 33,163,320 | 32,374,299 | -62,526,962 | 31,298,052 | |
| EBITDA | $-45M | $-42M | · | $-47M | $-47M | $-22M | · | $-22M | $53M | $21M | · | $14M | $-16M | · | · | $-26M |
Balance general 21
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $99M | $76M | $90M | $93M | $72M | $68M | $101M | $78M | $185M | $68M | $68M | $52M | $80M | $228M | $45M | $53M | |
| Short-term Investments | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $162M | |
| Prepaid Expense | $9M | $11M | $9M | $10M | $14M | $19M | $16M | $13M | $12M | $9M | $12M | $24M | $10M | $16M | $21M | $19M | |
| Current Assets | $233M | $267M | $306M | $338M | $369M | $403M | $440M | $465M | $490M | $414M | $370M | $383M | $390M | $434M | $210M | $235M | |
| PP&E (Net) | $6M | $7M | $7M | $8M | $10M | $11M | $11M | $11M | $11M | $11M | $11M | $11M | $11M | $9M | $8M | $7M | |
| PP&E (Gross) | $16M | $17M | $17M | $19M | $21M | $21M | $20M | $19M | $19M | $18M | $17M | $16M | $15M | $13M | $11M | $10M | |
| Accum. Depreciation | $11M | $10M | $10M | $10M | $11M | $10M | $9M | $8M | $8M | $7M | $6M | $5M | $4M | $4M | $3M | $3M | |
| Other Non-current Assets | $118.0K | $90.0K | $70.0K | $163.0K | $199.0K | $239.0K | $284.0K | $746.0K | $747.0K | $3M | $3M | $3M | $538.0K | $14M | $5M | $954.0K | |
| Total Assets | $299M | $336M | $377M | $413M | $449M | $486M | $526M | $555M | $582M | $511M | $469M | $485M | $494M | $476M | $252M | $274M | |
| Accounts Payable | $4M | $3M | $2M | $3M | $2M | $2M | $4M | $1M | $2M | $3M | $3M | $752.0K | $2M | $6M | $6M | $1M | |
| Accrued Liabilities | $13M | $12M | $18M | $16M | $12M | $8M | $13M | $13M | $11M | $9M | $11M | $10M | $7M | $12M | $8M | $12M | |
| Current Liabilities | $21M | $19M | $24M | $24M | $20M | $18M | $39M | $71M | $86M | $174M | $159M | $165M | $126M | $148M | $22M | $22M | |
| Capital Leases | $44M | $45M | $47M | $48M | $49M | $50M | $52M | $54M | $56M | $58M | $60M | $62M | $66M | $9M | $18M | $20M | |
| Total Liabilities | $65M | $65M | $71M | $72M | $69M | $69M | $98M | $132M | $152M | $241M | $227M | $238M | $287M | $246M | $40M | $41M | |
| Common Stock | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | $3.0K | |
| Paid-in Capital | $589M | $583M | $579M | $574M | $569M | $564M | $558M | $552M | $547M | $441M | $437M | $433M | $429M | $425M | $403M | $400M | |
| Retained Earnings | $-356M | $-313M | $-273M | $-234M | $-190M | $-147M | $-129M | $-130M | $-116M | $-171M | $-195M | $-185M | $-221M | $-195M | $-188M | $-164M | |
| AOCI | $66.0K | $246.0K | $652.0K | $621.0K | $400.0K | $437.0K | $-43.0K | $972.0K | $-329.0K | $-246.0K | $195.0K | $-496.0K | $-1M | $-642.0K | $-2M | $-3M | |
| Stockholders' Equity | $233M | $271M | $306M | $341M | $380M | $417M | $429M | $422M | $430M | $269M | $242M | $247M | $207M | $230M | $213M | $233M | |
| Liabilities + Equity | $299M | $336M | $377M | $413M | $449M | $486M | $526M | $555M | $582M | $511M | $469M | $485M | $494M | $476M | $252M | $274M | |
| Shares Outstanding | 38,936,669 | 38,820,616 | 38,284,221 | 38,219,232 | 38,033,970 | 37,942,283 | 37,574,538 | 37,400,499 | 37,172,496 | 33,604,053 | 33,437,296 | 33,340,216 | 33,205,693 | 33,133,736 | 31,394,767 | 31,325,373 |
Flujo de Efectivo 9
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $5M | $5M | $4M | $5M | $5M | $5M | $5M | $5M | $5M | $4M | $4M | $3M | $3M | $3M | $3M | $3M | |
| Operating Cash Flow | $-32M | $-42M | $-32M | $-28M | $-29M | $-39M | $-32M | $-24M | $40M | $-26M | $-4M | $-24M | $-35M | $203M | $-27M | $-27M | |
| CapEx | $11.0K | $44.0K | $-207.0K | $-171.0K | $275.0K | $1M | $635.0K | $639.0K | $1M | $838.0K | $976.0K | $1M | $2M | $2M | $708.0K | $810.0K | |
| Investing Cash Flow | $55M | $27M | $29M | $49M | $34M | $5M | $53M | $-83M | $-24M | $26M | $19M | $-4M | $-113M | $-40M | $19M | $-10M | |
| Stock Issued | · | · | · | $0 | · | · | · | $-392.0K | $100M | $0 | · | $0 | $0 | $19M | · | $0 | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $0 | · | · | · | · | · | · | |
| Financing Cash Flow | $350.0K | $100.0K | $192.0K | $8.0K | $337.0K | $350.0K | $1M | $-11.0K | $101M | $206.0K | $690.0K | $368.0K | $443.0K | $20M | $358.0K | $60.0K | |
| Net Change in Cash | $23M | $-15M | $-3M | $21M | $5M | $-33M | $23M | $-107M | $117M | $834.0K | $16M | $-28M | $-148M | $182M | $-8M | $-38M | |
| Free Cash Flow | · | $-42M | · | · | · | $-40M | · | · | · | $-26M | · | · | · | · | · | · |
Rentabilidad 5
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating Margin | -5007.0% | -4834.6% | · | -2915.2% | -2402.5% | -106.0% | · | -110.7% | 56.4% | 35.7% | · | 32.0% | -89.7% | · | · | · | |
| Net Margin | -4762.0% | -4539.1% | · | -2734.4% | -2210.4% | -84.4% | · | -71.7% | 58.1% | 39.7% | · | 81.1% | -142.7% | · | · | · | |
| EBITDA Margin | -5007.0% | -4834.6% | · | -2915.2% | -2402.5% | -106.0% | · | -110.7% | 56.4% | 35.7% | · | 32.0% | -89.7% | · | · | · | |
| ROA | -11.4% | -9.7% | · | -9.1% | -8.4% | -3.5% | · | -2.7% | 10.2% | 4.8% | · | 9.3% | -6.6% | · | · | -12.4% | |
| ROE | -14.0% | -11.5% | · | -11.6% | -10.7% | -5.1% | · | -4.2% | 17.3% | 9.4% | · | 14.8% | -11.2% | · | · | -31.3% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 10.9 | 13.9 | · | 14.1 | 18.6 | 21.9 | · | 6.6 | 5.7 | 2.4 | · | 2.3 | 3.1 | · | · | 10.9 | |
| Quick Ratio | 4.6 | 4.0 | · | 3.9 | 3.7 | 3.7 | · | 1.1 | 2.2 | 0.4 | · | 0.3 | 0.6 | · | · | 10.0 |
Eficiencia 1
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Asset Turnover | 0.0 | 0.0 | · | 0.0 | 0.0 | 0.0 | · | 0.0 | 0.2 | 0.1 | · | 0.1 | 0.0 | · | · | · |
Valoración (TTM) 10
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue TTM | $5M | $25M | · | $44M | $137M | $194M | · | $217M | $216M | $146M | · | $87M | $43M | $25M | · | · | |
| Net Income TTM | $-170M | $-144M | · | $-119M | $-19M | $47M | · | $100M | $88M | $26M | · | $-22M | $-81M | $-77M | · | $-84M | |
| Market Cap | $287M | $490M | · | $222M | $256M | $343M | · | $598M | $530M | $476M | · | $527M | $503M | · | · | $494M | |
| P/E | -1.8 | -3.6 | · | -2.0 | -25.8 | 6.2 | · | 5.5 | 5.8 | 20.0 | · | -20.5 | -6.0 | -5.9 | · | -1.3 | |
| P/S | 53.7 | 19.6 | · | 5.1 | 1.9 | 1.8 | · | 2.8 | 2.5 | 3.3 | · | 6.0 | 11.6 | · | · | · | |
| P/B | 1.2 | 1.8 | · | 0.7 | 0.7 | 0.8 | · | 1.4 | 1.2 | 1.8 | · | 2.1 | 2.4 | · | · | 2.1 | |
| P / Tangible Book | 1.2 | 1.8 | · | 0.7 | 0.7 | 0.8 | · | 1.4 | 1.2 | 1.8 | · | 2.1 | 2.4 | 2.1 | · | 2.1 | |
| P / Cash Flow | · | -11.8 | · | · | · | -8.9 | · | · | · | -18.7 | · | · | · | · | · | · | |
| P / FCF | · | -11.7 | · | · | · | -8.7 | · | · | · | -18.1 | · | · | · | · | · | · | |
| Earnings Yield | -55.2% | -27.5% | · | -49.5% | -3.9% | 16.2% | · | 18.1% | 17.3% | 5.0% | · | -4.9% | -16.7% | -16.8% | · | -76.2% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ingresos | $25M | $211M | $129M | — | — |
| Margen Operativo % | -621.1% | 22.3% | -2.5% | — | — |
| Beneficio neto | $-144M | $66M | $-7M | $-95M | $-51M |
| EPS Diluido | $-3.47 | $1.68 | $-0.20 | $-3.02 | $-8.16 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 12.5 | 11.1 | 2.3 | — | 44.5 |
| Ratio Rápido | 3.7 | 2.6 | 0.4 | — | 43.3 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-130M | $-45M | $134M | — | $-55M |
Mis Métricas Tu lista de seguimiento personal — filas seleccionadas de Fundamentales Completos
Elige las métricas que te importan — haz clic en el ➕ junto a cualquier fila en Fundamentales Completos arriba.
Tu selección se guarda y te sigue en todos los tickers.
Propietarios institucionales (13F) 137 declarantes · $224.4M total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 34 (+17 vs trimestre anterior) | 16 (+4 vs trimestre anterior) | 47 (+2 vs trimestre anterior) | 30 (0 vs trimestre anterior) | +4.6M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | $37 335 293 | 5 072 730 | 16,63% | Acciones |
| 5AM Venture Management, LLC | $29 854 949 | 4 056 379 | 13,30% | Acciones |
| MPM ASSET MANAGEMENT LLC | $25 410 160 | 4 381 062 | 11,32% | Acciones |
| VANGUARD GROUP INC | $15 056 160 | 1 464 607 | 6,71% | Acciones |
| Merck & Co., Inc. | $12 804 692 | 1 739 768 | 5,71% | Acciones |
| StepStone Group LP | $9 607 316 | 761 277 | 4,28% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $9 344 506 | 1 269 634 | 4,16% | Acciones |
| MPM BIOIMPACT LLC | $9 222 470 | 1 253 053 | 4,11% | Acciones |
| TCG Crossover Management, LLC | $7 803 293 | 1 060 230 | 3,48% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $7 024 524 | 954 419 | 3,13% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $5 622 738 | 763 959 | 2,51% | Acciones |
| AQR CAPITAL MANAGEMENT LLC | $5 114 103 | 694 851 | 2,28% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $4 548 555 | 617 863 | 2,03% | Acciones |
| STATE STREET CORP | $4 391 543 | 596 677 | 1,96% | Acciones |
| JPMORGAN CHASE & CO | $3 170 992 | 411 283 | 1,41% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $2 523 148 | 342 819 | 1,12% | Acciones |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2 233 458 | 303 459 | 1,00% | Acciones |
| Nantahala Capital Management, LLC | $2 212 232 | 300 575 | 0,99% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 870 397 | 254 130 | 0,83% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $1 450 921 | 197 136 | 0,65% | Acciones |
| Longaeva Partners L.P. | $1 436 944 | 195 237 | 0,64% | Acciones |
| RENAISSANCE TECHNOLOGIES LLC | $1 405 760 | 191 000 | 0,63% | Acciones |
| Quantinno Capital Management LP | $1 389 855 | 188 839 | 0,62% | Acciones |
| Lynx1 Capital Management LP | $1 314 540 | 178 606 | 0,59% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $1 233 875 | 167 646 | 0,55% | Acciones |
| BlackRock, Inc. | $1 216 689 | 165 311 | 0,54% | Acciones |
| Woodline Partners LP | $1 071 616 | 145 600 | 0,48% | Acciones |
| Trexquant Investment LP | $1 031 452 | 140 143 | 0,46% | Acciones |
| GOLDMAN SACHS GROUP INC | $1 022 262 | 138 894 | 0,46% | Acciones |
| MOORE CAPITAL MANAGEMENT, LP | $772 800 | 105 000 | 0,34% | Acciones |
| Cubist Systematic Strategies, LLC | $711 521 | 122 676 | 0,32% | Acciones |
| XTX Topco Ltd | $701 680 | 95 337 | 0,31% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $699 524 | 95 044 | 0,31% | Acciones |
| Allspring Global Investments Holdings, LLC | $688 440 | 93 538 | 0,31% | Acciones |
| ROYCE & ASSOCIATES LP | $610 159 | 82 902 | 0,27% | Acciones |
| AMERICAN CENTURY COMPANIES INC | $586 599 | 79 701 | 0,26% | Acciones |
| CITADEL ADVISORS LLC | $551 058 | 74 872 | 0,25% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $533 747 | 72 520 | 0,24% | Acciones |
| AMERIPRISE FINANCIAL INC | $518 107 | 70 395 | 0,23% | Acciones |
| Qube Research & Technologies Ltd | $448 018 | 60 872 | 0,20% | Acciones |
| CANTOR FITZGERALD, L. P. | $441 600 | 60 000 | 0,20% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $399 297 | 31 640 | 0,18% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $398 272 | 54 113 | 0,18% | Acciones |
| TD Asset Management Inc | $394 408 | 53 588 | 0,18% | Acciones |
| ExodusPoint Capital Management, LP | $388 365 | 52 767 | 0,17% | Acciones |
| Nan Fung Group Holdings Ltd | $361 244 | 49 082 | 0,16% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $341 519 | 46 402 | 0,15% | Acciones |
| BANK OF AMERICA CORP /DE/ | $314 265 | 42 699 | 0,14% | Acciones |
| MARTINGALE ASSET MANAGEMENT L P | $281 616 | 38 263 | 0,13% | Acciones |
| HSBC HOLDINGS PLC | $278 266 | 36 470 | 0,12% | Acciones |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $276 015 | 37 502 | 0,12% | Acciones |
| RHUMBLINE ADVISERS | $270 421 | 36 743 | 0,12% | Acciones |
| Y-Intercept (Hong Kong) Ltd | $255 296 | 34 687 | 0,11% | Acciones |
| Brevan Howard Capital Management LP | $250 012 | 33 969 | 0,11% | Acciones |
| Graham Capital Management, L.P. | $246 244 | 33 457 | 0,11% | Acciones |
| D. E. Shaw & Co., Inc. | $238 442 | 32 397 | 0,11% | Acciones |
| Odyssean, LLC | $230 405 | 31 305 | 0,10% | Acciones |
| Corton Capital Inc. | $225 324 | 38 849 | 0,10% | Acciones |
| IEQ CAPITAL, LLC | $218 437 | 29 679 | 0,10% | Acciones |
| Point72 Asset Management, L.P. | $209 760 | 28 500 | 0,09% | Acciones |
| China Universal Asset Management Co., Ltd. | $204 446 | 27 778 | 0,09% | Acciones |
| BARCLAYS PLC | $204 298 | 27 758 | 0,09% | Acciones |
| Verdad Advisers, LP | $202 400 | 27 500 | 0,09% | Acciones |
| Bank of New York Mellon Corp | $198 661 | 26 992 | 0,09% | Acciones |
| DEUTSCHE BANK AG\ | $195 452 | 26 556 | 0,09% | Acciones |
| Voleon Capital Management LP | $186 385 | 25 324 | 0,08% | Acciones |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $184 000 | 25 000 | 0,08% | Acciones |
| WELLS FARGO & COMPANY/MN | $181 395 | 24 646 | 0,08% | Acciones |
| Inscription Capital, LLC | $176 206 | 23 941 | 0,08% | Acciones |
| AlphaQuest LLC | $160 666 | 15 629 | 0,07% | Acciones |
| Mariner, LLC | $159 779 | 21 707 | 0,07% | Acciones |
| MERCER GLOBAL ADVISORS INC /ADV | $152 006 | 20 653 | 0,07% | Acciones |
| MetLife Investment Management, LLC | $129 941 | 17 655 | 0,06% | Acciones |
| ADAR1 Capital Management, LLC | $114 080 | 15 500 | 0,05% | Acciones |
| PANAGORA ASSET MANAGEMENT INC | $114 028 | 15 493 | 0,05% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $99 735 | 13 551 | 0,04% | Acciones |
| Quadrature Capital Ltd | $97 572 | 13 257 | 0,04% | Acciones |
| CITIGROUP INC | $96 357 | 13 092 | 0,04% | Acciones |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $88 364 | 12 769 | 0,04% | Acciones |
| CWM, LLC | $85 665 | 6 788 | 0,04% | Acciones |
| Invesco Ltd. | $85 656 | 11 638 | 0,04% | Acciones |
| Cerity Partners LLC | $72 091 | 9 795 | 0,03% | Acciones |
| Police & Firemen's Retirement System of New Jersey | $69 707 | 9 471 | 0,03% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $65 335 | 8 877 | 0,03% | Acciones |
| Vanguard Global Advisers, LLC | $64 856 | 8 812 | 0,03% | Acciones |
| MORGAN STANLEY | $39 494 | 5 366 | 0,02% | Acciones |
| State of Wyoming | $36 903 | 5 014 | 0,02% | Acciones |
| NORTHERN TRUST CORP | $34 489 | 4 686 | 0,02% | Acciones |
| Arax Advisory Partners | $32 958 | 4 478 | 0,01% | Acciones |
| Versant Capital Management, Inc | $31 067 | 4 221 | 0,01% | Acciones |
| Nuveen Asset Management, LLC | $26 454 | 1 530 | 0,01% | Acciones |
| STRS OHIO | $23 552 | 3 200 | 0,01% | Acciones |
| NISA INVESTMENT ADVISORS, LLC | $21 874 | 2 972 | 0,01% | Acciones |
| Tower Research Capital LLC (TRC) | $21 462 | 2 916 | 0,01% | Acciones |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $19 784 | 2 688 | 0,01% | Acciones |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $19 435 | 1 540 | 0,01% | Acciones |
| Legal & General Group Plc | $18 807 | 2 557 | 0,01% | Acciones |
| Ameritas Investment Partners, Inc. | $17 789 | 2 417 | 0,01% | Acciones |
| FMR LLC | $15 692 | 2 132 | 0,01% | Acciones |
| FEDERATED HERMES, INC. | $14 484 | 1 968 | 0,01% | Acciones |
Informantes de la empresa 14 insiders · 5 directivos · 9 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Dipal Doshi | President and CEO | 1 de septiembre de 2022 A | 221 835 | 0 | 0 | $0 |
| Kory James Wentworth | Chief Financial Officer | 1 de septiembre de 2022 A | 16 489 | 0 | 0 | $0 |
| Nathan J Dowden | Chief Operating Officer | 1 de septiembre de 2022 A | 70 525 | 0 | 0 | $0 |
| Natarajan Sethuraman | Chief Scientific Officer | 1 de septiembre de 2022 A | 162 144 | 0 | 0 | $0 |
| Nerissa Kreher | Chief Medical Officer | 1 de septiembre de 2022 A | 20 716 | 0 | 0 | $0 |
| Maha Radhakrishnan | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| Gina Chapman | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| Bernhardt G Zeiher | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| Mary Thistle | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| Peter S Kim | Consejero | 10 de junio de 2026 A | — | 0 | 0 | $0 |
| John F Crowley | Consejero | 8 de junio de 2023 A | 5 000 | 0 | 0 | $0 |
| Carole Nuechterlein | Consejero | 2 de junio de 2022 A | — | 0 | 0 | $0 |
| Todd Foley | Consejero | 2 de junio de 2022 A | 4 425 784 | 0 | 0 | $0 |
| Kush Parmar | — | 10 de agosto de 2026 S | 2 691 337 | 0 | 5 | $-1 885 964 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 4 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| 5AM Ventures V, L.P., 5AM Partners V, LLC, 5AM Opportunities I, L.P., 5AM Opportunities I (GP), LLC, Andrew J. Schwab, Kush Parmar, Scott M. Rocklage | 18 de noviembre de 2025 | 10,80% | Enmienda | — | SEC |
| Baker Bros. Advisors LP, Baker Bros. Advisors (GP) LLC, Felix J. Baker, Julian C. Baker ×2 presentaciones | 26 de junio de 2024 | — | Presentación inicial | — | SEC |
| 5AM Partners V, LLC, 5AM Opportunities I, L.P., 5AM Opportunities I (GP), LLC, Andrew J. Schwab, Dr. Kush Parmar, Dr. Scott M. Rocklage | 12 de noviembre de 2021 | — | Presentación inicial | — | SEC |
| MPM BioVentures 2014, L.P., MPM BioVentures 2014 (B), L.P., MPM Asset Management Investors BV2014 LLC, MPM BioVentures 2018, L.P., MPM BioVentures 2018 (B), L.P., MPM Asset Management Investors BV2018 LLC, MPM BioVentures 2014 GP LLC, MPM BioVentures 2014 LLC, MPM BioVentures 2018 GP LLC, MPM BioVentures 2018 LLC, Ansbert Gadicke, Luke Evnin, Todd Foley, Edward Hurwitz | 12 de noviembre de 2021 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 34 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| IBRN · iShares Trust | 0,16% | 1 770 SH | 8 de agosto de 2026 | Diario |
| HAPS · Harbor ETF Trust | 0,16% | 18 286 NS | 30 de abril de 2026 | N-PORT |
| IWC · iShares Trust | 0,05% | 100 950 SH | 8 de agosto de 2026 | Diario |
| GSSC · Goldman Sachs ETF Trust | 0,02% | 33 055 NS | 31 de mayo de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,02% | 2 093 SH | 8 de agosto de 2026 | Diario |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,02% | 69 412 NS | 31 de mayo de 2026 | N-PORT |
| BIB · ProShares Trust | 0,01% | 1 416 NS | 31 de mayo de 2026 | N-PORT |
| IWN · iShares Trust | 0,01% | 268 344 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,01% | 12 375 NS | 30 de abril de 2026 | N-PORT |
| IBB · iShares Trust | 0,01% | 155 936 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,01% | 169 170 SH | 8 de agosto de 2026 | Diario |
| VTWV · VANGUARD SCOTTSDALE FUNDS | 0,01% | 25 636 SH | 8 de agosto de 2026 | Diario |
| DFAS · Dimensional ETF Trust | 0,01% | 100 802 NS | 30 de abril de 2026 | N-PORT |
| IWM · iShares Trust | 0,01% | 752 460 SH | 8 de agosto de 2026 | Diario |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,01% | 27 048 SH | 8 de agosto de 2026 | Diario |
| ITWO · ProShares Trust | 0,01% | 1 340 NS | 31 de mayo de 2026 | N-PORT |
| DFSV · Dimensional ETF Trust | 0,00% | 27 316 NS | 30 de abril de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,00% | 113 479 NS | 31 de mayo de 2026 | N-PORT |
| UWM · ProShares Trust | 0,00% | 1 047 NS | 31 de mayo de 2026 | N-PORT |
| DXUV · Dimensional ETF Trust | 0,00% | 800 NS | 30 de abril de 2026 | N-PORT |
| URTY · ProShares Trust | 0,00% | 1 057 NS | 31 de mayo de 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,00% | 742 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 27 NS | 31 de mayo de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 7 570 NS | 30 de abril de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 888 NS | 31 de mayo de 2026 | N-PORT |
| AVUS · AMERICAN CENTURY ETF TRUST | 0,00% | 6 979 NS | 31 de mayo de 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 7 594 SH | 8 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 17 261 NS | 31 de mayo de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 1 647 NS | 30 de abril de 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,00% | 2 069 NS | 30 de abril de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,00% | 283 038 SH | 8 de agosto de 2026 | Diario |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 953 727 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 1 999 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,00% | 57 325 SH | 8 de agosto de 2026 | Diario |