SION Sionna Therapeutics, Inc. - Common Stock
SION Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
SION Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
SION Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
- Compra fuerte 7 41,2%
- Compra 7 41,2%
- Mantener 2 11,8%
- Venta 1 5,9%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
6 analistas · 2026-08-18Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.66 | $-0.66 | 0.00% |
| 31 de marzo de 2026 | $-0.60 | $-0.52 | -0.08% |
| 31 de diciembre de 2025 | $-0.46 | $-0.55 | 0.09% |
| 30 de septiembre de 2025 | $-0.46 | $-0.49 | 0.03% |
| 30 de junio de 2025 | $-0.41 | $-0.57 | 0.16% |
| 31 de marzo de 2025 | $-0.62 | $-0.46 | -0.16% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| SION | $1.84B | -21.9 | — | — | -23.4% | — |
| MYGN | $575M | -1.6 | -1.6% | -44.4% | -96.8% | 69.9% |
| ANIK | $133M | -12.6 | -5.9% | -9.6% | -7.5% | 56.6% |
| TRDA | $394M | -3.0 | -87.9% | -565.5% | -41.9% | — |
| RNAC | $188M | -1.4 | -92.8% | -4658.6% | 202.4% | — |
| SRZN | — | — | — | — | — | — |
| ZSQR | — | — | — | — | — | — |
| MGNX | $102M | -1.4 | -0.31% | -49.9% | -87.0% | — |
| ALXO | $61M | -0.6 | — | — | -225.0% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 13
| Métrica | Tendencia | 2025 | 2024 |
|---|---|---|---|
| R&D Expense | $60M | $57M | |
| SG&A Expense | $29M | $13M | |
| Operating Expenses | $89M | $71M | |
| Operating Income | $-89M | $-71M | |
| Interest Income | $13M | $8M | |
| Other Non-op | $14M | $9M | |
| Income Tax | $0 | $0 | |
| Net Income | $-75M | $-62M | |
| EPS (Basic) | $-1.88 | $-15.99 | |
| EPS (Diluted) | $-1.88 | $-15.99 | |
| Shares (Basic) | 39,962,163 | 3,858,859 | |
| Shares (Diluted) | 39,962,163 | 3,858,859 | |
| EBITDA | $-89M | · |
Balance general 19
| Métrica | Tendencia | 2025 | 2024 |
|---|---|---|---|
| Cash & Equivalents | $58M | $38M | |
| Prepaid Expense | $6M | $3M | |
| Current Assets | $241M | $151M | |
| PP&E (Net) | $2M | $2M | |
| PP&E (Gross) | $4M | $4M | |
| Accum. Depreciation | $2M | $2M | |
| Other Non-current Assets | $0 | $3M | |
| Total Assets | $326M | $186M | |
| Accrued Liabilities | $10M | $8M | |
| Current Liabilities | $12M | $10M | |
| Capital Leases | $7M | $9M | |
| Total Liabilities | $19M | $19M | |
| Common Stock | $45.0K | $5.0K | |
| Paid-in Capital | $563M | $17M | |
| Retained Earnings | $-256M | $-181M | |
| AOCI | $540.0K | $368.0K | |
| Stockholders' Equity | $307M | $-164M | |
| Liabilities + Equity | $326M | $186M | |
| Shares Outstanding | 44,723,585 | 4,722,763 |
Flujo de Efectivo 7
| Métrica | Tendencia | 2025 | 2024 |
|---|---|---|---|
| Stock-based Comp | $12M | $4M | |
| Operating Cash Flow | $-66M | $-53M | |
| CapEx | $377.0K | $27.0K | |
| Investing Cash Flow | $-119M | $-127M | |
| Financing Cash Flow | $206M | $179M | |
| Net Change in Cash | $21M | $-733.0K | |
| Free Cash Flow | $-67M | · |
Rentabilidad 2
| Métrica | Tendencia | 2025 | 2024 |
|---|---|---|---|
| ROA | -29.4% | · | |
| ROE | -23.4% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 |
|---|---|---|---|
| Current Ratio | 20.6 | · | |
| Quick Ratio | 5.0 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 |
|---|---|---|---|
| Net Income TTM | $-75M | $-62M | |
| Market Cap | $1.84B | · | |
| P/E | -21.9 | · | |
| P/B | 6.0 | · | |
| P / Tangible Book | 6.0 | · | |
| P / Cash Flow | -27.8 | · | |
| P / FCF | -27.6 | · | |
| Earnings Yield | -4.6% | · |
Estado de resultados 12
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|---|
| R&D Expense | $22M | $19M | $15M | $16M | $15M | $14M | $14M | |
| SG&A Expense | $11M | $11M | $8M | $8M | $7M | $6M | $4M | |
| Operating Expenses | $32M | $30M | $24M | $24M | $22M | $20M | $18M | |
| Operating Income | $-32M | $-30M | $-24M | $-24M | $-22M | $-20M | $-18M | |
| Interest Income | $3M | $3M | $3M | $3M | $4M | $3M | $2M | |
| Other Non-op | $3M | $3M | $3M | $4M | $4M | $3M | $2M | |
| Net Income | $-30M | $-27M | $-20M | $-20M | $-18M | $-16M | $-16M | |
| EPS (Basic) | $-0.66 | $-0.60 | $1028.58 | $-0.46 | $-0.41 | $-0.62 | $6539.68 | |
| EPS (Diluted) | $-0.66 | $-0.60 | $1028.58 | $-0.46 | $-0.41 | $-0.62 | $6539.68 | |
| Shares (Basic) | 45,148,971 | 44,921,984 | -75,005,946 | 44,255,053 | 44,116,997 | 26,596,059 | -6,869,404 | |
| Shares (Diluted) | 45,148,971 | 44,921,984 | -75,005,946 | 44,255,053 | 44,116,997 | 26,596,059 | -6,869,404 | |
| EBITDA | $-32M | $-30M | · | $-24M | $-22M | $-20M | · |
Balance general 19
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $63M | $63M | $58M | $51M | $41M | $83M | $38M | |
| Prepaid Expense | $5M | $5M | $6M | $4M | $4M | $4M | $3M | |
| Current Assets | $216M | $221M | $241M | $252M | $267M | $274M | $151M | |
| PP&E (Net) | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| PP&E (Gross) | $4M | $4M | $4M | $4M | $4M | $4M | $4M | |
| Accum. Depreciation | $2M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Other Non-current Assets | $594.0K | $585.0K | $0 | $0 | $0 | $0 | $3M | |
| Total Assets | $283M | $305M | $326M | $339M | $352M | $370M | $186M | |
| Accrued Liabilities | $9M | $6M | $10M | $7M | $5M | $3M | $8M | |
| Current Liabilities | $11M | $10M | $12M | $10M | $8M | $10M | $10M | |
| Capital Leases | $7M | $7M | $7M | $8M | $8M | $8M | $9M | |
| Total Liabilities | $17M | $17M | $19M | $18M | $16M | $18M | $19M | |
| Common Stock | $45.0K | $45.0K | $45.0K | $44.0K | $44.0K | $44.0K | $5.0K | |
| Paid-in Capital | $579M | $571M | $563M | $557M | $552M | $549M | $17M | |
| Retained Earnings | $-313M | $-283M | $-256M | $-236M | $-216M | $-198M | $-181M | |
| AOCI | $-448.0K | $-84.0K | $540.0K | $420.0K | $183.0K | $301.0K | $368.0K | |
| Stockholders' Equity | $266M | $288M | $307M | $322M | $336M | $352M | $-164M | |
| Liabilities + Equity | $283M | $305M | $326M | $339M | $352M | $370M | $186M | |
| Shares Outstanding | 45,164,239 | 45,075,651 | 44,723,585 | 44,463,527 | 44,132,338 | 44,092,117 | 4,722,763 |
Flujo de Efectivo 7
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $7M | $7M | $4M | $3M | $3M | $2M | $1M | |
| Operating Cash Flow | $-22M | $-22M | $-17M | $-15M | $-18M | $-16M | $-12M | |
| CapEx | $0 | $0 | $204.0K | $87.0K | $0 | $86.0K | $27.0K | |
| Investing Cash Flow | $21M | $25M | $23M | $23M | $-23M | $-141M | $15M | |
| Financing Cash Flow | $749.0K | $2M | $2M | $2M | $-312.0K | $202M | $-1M | |
| Net Change in Cash | $-2.0K | $5M | $8M | $10M | $-42M | $45M | $2M | |
| Free Cash Flow | · | $-22M | · | · | · | $-16M | · |
Rentabilidad 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|---|
| ROA | -9.4% | -7.9% | · | -11.9% | -10.3% | -8.9% | · | |
| ROE | -9.9% | -8.4% | · | -12.6% | -10.7% | -9.4% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 20.0 | 22.6 | · | 25.6 | 35.3 | 28.7 | · | |
| Quick Ratio | 5.9 | 6.5 | · | 5.2 | 5.4 | 8.7 | · |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-95M | $-82M | · | $-80M | $-69M | $-62M | · | |
| Market Cap | $1.99B | $1.81B | · | $1.31B | $766M | $461M | · | |
| P/E | -20.7 | -0.1 | · | -0.0 | -0.0 | -0.0 | · | |
| P/B | 7.5 | 6.3 | · | 4.1 | 2.3 | 1.3 | · | |
| P / Tangible Book | 7.5 | 6.3 | · | 4.1 | 2.3 | 1.3 | · | |
| P / Cash Flow | · | -82.7 | · | · | · | -28.3 | · | |
| P / FCF | · | -82.7 | · | · | · | -28.2 | · | |
| Earnings Yield | -4.8% | -1026.9% | · | -3523.0% | -21588.9% | -68601.1% | · |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | |
|---|---|---|
| Beneficio neto | $-75M | $-62M |
| EPS Diluido | $-1.88 | $-15.99 |
Balance general
| 2025-12-31 | 2024-12-31 | |
|---|---|---|
| Ratio corriente | 20.6 | — |
| Ratio Rápido | 5.0 | — |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | |
|---|---|---|
| Flujo de caja libre | $-67M | — |
Últimas noticias Noticias recientes que mencionan a esta empresa
Mis Métricas Tu lista de seguimiento personal — filas seleccionadas de Fundamentales Completos
Elige las métricas que te importan — haz clic en el ➕ junto a cualquier fila en Fundamentales Completos arriba.
Tu selección se guarda y te sigue en todos los tickers.
Propietarios institucionales (13F) 158 declarantes · $2.0B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 49 (+21 vs trimestre anterior) | 6 (-4 vs trimestre anterior) | 49 (+12 vs trimestre anterior) | 36 (+8 vs trimestre anterior) | +3.7M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $435 722 930 | 9 905 045 | 21,94% | Acciones |
| TPG GP A, LLC | $285 713 378 | 6 494 962 | 14,39% | Acciones |
| VIKING GLOBAL INVESTORS LP | $140 556 012 | 3 195 181 | 7,08% | Acciones |
| Atlas Venture Life Science Advisors, LLC | $131 776 532 | 2 995 602 | 6,64% | Acciones |
| ORBIMED ADVISORS LLC | $112 433 029 | 2 555 877 | 5,66% | Acciones |
| ENAVATE SCIENCES GP, LLC | $109 008 540 | 2 478 030 | 5,49% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $70 384 000 | 1 600 000 | 3,54% | Acciones |
| JENNISON ASSOCIATES LLC | $51 562 131 | 1 172 133 | 2,60% | Acciones |
| CITADEL ADVISORS LLC | $50 143 057 | 1 139 874 | 2,52% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $49 796 724 | 1 132 001 | 2,51% | Acciones |
| STATE STREET CORP | $44 937 281 | 1 021 534 | 2,26% | Acciones |
| VANGUARD GROUP INC | $44 053 411 | 1 070 817 | 2,22% | Acciones |
| PERCEPTIVE ADVISORS LLC | $39 810 950 | 905 000 | 2,00% | Acciones |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $29 953 495 | 680 916 | 1,51% | Acciones |
| Siren, L.L.C. | $26 856 555 | 610 515 | 1,35% | Acciones |
| EVENTIDE ASSET MANAGEMENT, LLC | $20 894 402 | 474 981 | 1,05% | Acciones |
| Casdin Capital, LLC | $17 596 000 | 400 000 | 0,89% | Acciones |
| BAKER BROS. ADVISORS LP | $17 596 000 | 400 000 | 0,89% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $17 528 912 | 398 380 | 0,88% | Acciones |
| Driehaus Capital Management LLC | $16 955 814 | 385 447 | 0,85% | Acciones |
| GOLDMAN SACHS GROUP INC | $16 100 032 | 365 993 | 0,81% | Acciones |
| FRANKLIN RESOURCES INC | $12 762 071 | 290 113 | 0,64% | Acciones |
| Aberdeen Group plc | $12 499 231 | 284 138 | 0,63% | Acciones |
| FMR LLC | $12 242 065 | 278 292 | 0,62% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $12 173 485 | 276 733 | 0,61% | Acciones |
| Candriam S.C.A. | $10 248 950 | 233 208 | 0,52% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $9 807 527 | 222 949 | 0,49% | Acciones |
| Kalehua Capital Management LLC | $8 669 197 | 197 072 | 0,44% | Acciones |
| Longaeva Partners L.P. | $8 637 524 | 196 352 | 0,43% | Acciones |
| Artisan Partners Limited Partnership | $8 336 017 | 189 498 | 0,42% | Acciones |
| Ensign Peak Advisors, Inc | $8 117 563 | 184 532 | 0,41% | Acciones |
| Soleus Capital Management, L.P. | $7 816 451 | 177 687 | 0,39% | Acciones |
| Sofinnova Investments, Inc. | $6 353 564 | 144 432 | 0,32% | Acciones |
| Qube Research & Technologies Ltd | $6 172 193 | 140 309 | 0,31% | Acciones |
| Alyeska Investment Group, L.P. | $5 992 406 | 136 222 | 0,30% | Acciones |
| GordonMD Global Investments LP | $5 982 640 | 136 000 | 0,30% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $5 707 834 | 129 753 | 0,29% | Acciones |
| Sio Capital Management, LLC | $5 622 274 | 127 808 | 0,28% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $5 342 234 | 121 442 | 0,27% | Acciones |
| Artia Global Partners LP | $5 267 407 | 119 741 | 0,27% | Acciones |
| UBS Group AG | $5 111 902 | 116 206 | 0,26% | Acciones |
| First Turn Management, LLC | $4 860 587 | 110 493 | 0,24% | Acciones |
| CITIGROUP INC | $4 799 265 | 109 099 | 0,24% | Acciones |
| Ikarian Capital, LLC | $4 728 925 | 107 500 | 0,24% | Opción de venta |
| Rock Springs Capital Management LP | $4 373 882 | 99 429 | 0,22% | Acciones |
| Walleye Capital LLC | $4 282 295 | 97 347 | 0,22% | Acciones |
| Rhenman & Partners Asset Management AB | $4 271 429 | 97 100 | 0,22% | Acciones |
| D. E. Shaw & Co., Inc. | $3 998 779 | 90 902 | 0,20% | Acciones |
| AMERIPRISE FINANCIAL INC | $3 617 386 | 82 232 | 0,18% | Acciones |
| Integral Health Asset Management, LLC | $3 299 250 | 75 000 | 0,17% | Acciones |
| BANK OF AMERICA CORP /DE/ | $3 272 636 | 74 395 | 0,16% | Acciones |
| SUPERSTRING CAPITAL MANAGEMENT LP | $2 778 232 | 63 156 | 0,14% | Acciones |
| STEMPOINT CAPITAL LP | $2 614 150 | 59 426 | 0,13% | Acciones |
| SEVEN GRAND MANAGERS, LLC | $2 199 500 | 50 000 | 0,11% | Acciones |
| Point72 Asset Management, L.P. | $2 169 939 | 49 328 | 0,11% | Acciones |
| TD Asset Management Inc | $2 084 950 | 47 396 | 0,10% | Acciones |
| ALPS ADVISORS INC | $2 002 645 | 45 525 | 0,10% | Acciones |
| SILVERARC CAPITAL MANAGEMENT, LLC | $1 868 607 | 42 478 | 0,09% | Acciones |
| XTX Topco Ltd | $1 675 843 | 38 096 | 0,08% | Acciones |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | $1 582 232 | 35 968 | 0,08% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 558 126 | 35 420 | 0,08% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $1 429 675 | 32 500 | 0,07% | Opción de venta |
| BNP PARIBAS FINANCIAL MARKETS | $1 399 014 | 31 803 | 0,07% | Acciones |
| Ishara Investments LP | $1 350 540 | 123 000 | 0,07% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $1 258 114 | 28 600 | 0,06% | Opción de venta |
| Swiss National Bank | $1 187 730 | 27 000 | 0,06% | Acciones |
| Quadrature Capital Ltd | $1 144 752 | 26 023 | 0,06% | Acciones |
| MORGAN STANLEY | $1 140 617 | 25 929 | 0,06% | Acciones |
| Trexquant Investment LP | $1 047 402 | 23 810 | 0,05% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $1 037 548 | 23 586 | 0,05% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $1 020 291 | 25 450 | 0,05% | Acciones |
| TUDOR INVESTMENT CORP ET AL | $993 074 | 22 575 | 0,05% | Acciones |
| RHUMBLINE ADVISERS | $981 362 | 22 309 | 0,05% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $879 800 | 20 000 | 0,04% | Opción de compra |
| Maven Securities LTD | $879 800 | 20 000 | 0,04% | Acciones |
| LOS ANGELES CAPITAL MANAGEMENT LLC | $820 193 | 18 645 | 0,04% | Acciones |
| Susquehanna Portfolio Strategies, LLC | $793 316 | 18 034 | 0,04% | Acciones |
| Rafferty Asset Management, LLC | $791 996 | 18 004 | 0,04% | Acciones |
| Shay Capital LLC | $791 820 | 18 000 | 0,04% | Acciones |
| Engineers Gate Manager LP | $686 376 | 15 603 | 0,03% | Acciones |
| BlackRock, Inc. | $576 269 | 13 100 | 0,03% | Acciones |
| KENNEDY CAPITAL MANAGEMENT LLC | $555 198 | 12 621 | 0,03% | Acciones |
| MARSHALL WACE, LLP | $554 230 | 12 599 | 0,03% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $515 651 | 11 722 | 0,03% | Acciones |
| MetLife Investment Management, LLC | $482 658 | 10 972 | 0,02% | Acciones |
| Bank of New York Mellon Corp | $476 500 | 10 832 | 0,02% | Acciones |
| Jump Financial, LLC | $460 708 | 10 473 | 0,02% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $419 445 | 9 535 | 0,02% | Acciones |
| PROFUND ADVISORS LLC | $402 069 | 9 140 | 0,02% | Acciones |
| Virtus Investment Advisers, LLC | $400 705 | 9 109 | 0,02% | Acciones |
| Russell Investments Group, Ltd. | $395 118 | 8 982 | 0,02% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $373 519 | 8 491 | 0,02% | Acciones |
| CITADEL ADVISORS LLC | $369 516 | 8 400 | 0,02% | Opción de venta |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $356 319 | 8 100 | 0,02% | Opción de compra |
| Vanguard Global Advisers, LLC | $345 409 | 7 852 | 0,02% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $338 723 | 7 700 | 0,02% | Opción de venta |
| Invesco Ltd. | $321 919 | 7 318 | 0,02% | Acciones |
| China Universal Asset Management Co., Ltd. | $316 112 | 7 186 | 0,02% | Acciones |
| Quarry LP | $296 933 | 6 750 | 0,01% | Acciones |
| VARCOV Co. | $282 328 | 6 418 | 0,01% | Acciones |
Informantes de la empresa 12 insiders · 4 directivos · 9 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Michael Cloonan | President & CEO | 6 de febrero de 2025 A | — | 0 | 0 | $0 |
| Elena Ridloff | CFO & Head of Corp. Dev. | 6 de febrero de 2025 A | — | 0 | 0 | $0 |
| Jennifer Fitzpatrick | Chief Legal Officer | 6 de julio de 2026 M | 0 | 0 | 1 | $-446 900 |
| Charlotte Mckee | Chief Medical Officer | 6 de febrero de 2025 A | — | 0 | 0 | $0 |
| Peter A. Thompson | Consejero | 7 de julio de 2026 S | 2 469 959 | 0 | 20 | $-55 674 636 |
| Marcella K. Ruddy | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Harold Edward Fleming | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Joanne L. Viney | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Joshua Resnick | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Laurie Stelzer | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
| Bruce Booth | Consejero | 17 de junio de 2026 A | 807 727 | 0 | 0 | $0 |
| Paul J Clancy | Consejero | 17 de junio de 2026 A | — | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 5 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| ORBIMED ADVISORS LLC, OrbiMed Capital GP VIII LLC ×2 presentaciones | 20 de abril de 2026 | 6,60% | Enmienda | — | SEC |
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P., RA Capital Nexus Fund III, L.P. ×2 presentaciones | 7 de noviembre de 2025 | 22,60% | Enmienda | — | SEC |
| Atlas Venture Fund XI, L.P., Atlas Venture Associates XI, L.P., Atlas Venture Associates XI, LLC, Atlas Venture Opportunity Fund II, L.P., Atlas Venture Associates Opportunity II, LP, Atlas Venture Associates Opportunity II, LLC ×2 presentaciones | 20 de octubre de 2025 | 5,40% | Enmienda | — | SEC |
| TPG GP A, LLC, James G. Coulter, Jon Winkelried | 18 de febrero de 2025 | 15,20% | Presentación inicial | — | SEC |
| Enavate Sciences GP, LLC, Sionna Aggregator, LP | 18 de febrero de 2025 | 5,60% | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 32 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1,23% | 46 379 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,67% | 6 453 NS | 30 de abril de 2026 | N-PORT |
| JDOC · J.P. Morgan Exchange-Traded Fund Tr… | 0,42% | 1 201 NS | 30 de abril de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,18% | 23 827 NS | 30 de abril de 2026 | N-PORT |
| ESSC · Strategy Shares | 0,16% | 1 066 NS | 30 de abril de 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,16% | 2 455 SH | 8 de agosto de 2026 | Diario |
| VFMO · VANGUARD WELLINGTON FUND | 0,12% | 55 058 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,10% | 193 943 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,10% | 1 651 NS | 31 de mayo de 2026 | N-PORT |
| IWO · iShares Trust | 0,06% | 168 969 SH | 8 de agosto de 2026 | Diario |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,05% | 19 765 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,03% | 474 105 SH | 8 de agosto de 2026 | Diario |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,02% | 4 592 NS | 30 de abril de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,02% | 5 028 NS | 31 de mayo de 2026 | N-PORT |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,02% | 106 139 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,02% | 7 105 NS | 30 de abril de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 764 NS | 31 de mayo de 2026 | N-PORT |
| ISCB · iShares Trust | 0,01% | 854 SH | 8 de agosto de 2026 | Diario |
| SCHA · SCHWAB STRATEGIC TRUST | 0,01% | 69 810 NS | 31 de mayo de 2026 | N-PORT |
| UWM · ProShares Trust | 0,01% | 598 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 168 317 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 40 627 SH | 8 de agosto de 2026 | Diario |
| URTY · ProShares Trust | 0,01% | 605 NS | 31 de mayo de 2026 | N-PORT |
| WSML · iShares Trust | 0,01% | 828 SH | 8 de agosto de 2026 | Diario |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 13 843 NS | 31 de mayo de 2026 | N-PORT |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 633 NS | 31 de mayo de 2026 | N-PORT |
| HDG · ProShares Trust | 0,00% | 15 NS | 31 de mayo de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 21 710 SH | 8 de agosto de 2026 | Diario |
| IWV · iShares Trust | 0,00% | 4 321 SH | 8 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 7 386 NS | 31 de mayo de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 934 641 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 1 360 SH | 8 de agosto de 2026 | Diario |