TYRA Tyra Biosciences, Inc. - Common Stock
$26,42
Precio · Ago 18, 2026
Fundamentales a fecha de Ago 4, 2026
Rango 52S
$10–$41
54% of range
Calificación del Analista
BUY
22 analysts
Precio Objetivo
$51
+92% upside
P/E (TTM)
-13.1
ROE
-42.7%
Margen de Beneficio Neto
—
TYRA Instantánea de la Acción Precio, capitalización bursátil, P/E, BPA, ROE, deuda/capital, rango de 52 semanas
Precio
$26.42
Capitalización Bursátil
$1.42B
P/E (TTM)
-13.1
BPA (TTM)
$-2.01
Ingresos (TTM)
—
Rendimiento div.
—
ROE
-42.7%
Deuda/Capital
—
Rango 52S
$10 – $41
TYRA Gráfico del Precio de la Acción OHLCV diario con indicadores técnicos — desplace, amplíe y personalice su vista
Configure
Rendimiento a 10 años Tendencias de ingresos, beneficio neto, márgenes y BPA
Ingresos y Beneficio Neto
—
BPA
$-2.01
2021-12-31
→
2025-12-31
Flujo de caja libre
$-95M
2021-12-31
→
2025-12-31
Márgenes
—
Valoración Ratios P/E, P/S, P/B, EV/EBITDA: ¿está la acción cara o barata?
Métrica
Tendencia a 5 años
TYRA
Mediana de Pares
P/E (TTM)
-13.1
—
P/B (P/C)
5.5
2.7
Price / FCF (Precio / FCF)
-14.9
—
Rentabilidad Márgenes brutos, operativos y netos; ROE, ROA, ROIC
Métrica
Tendencia a 5 años
TYRA
Mediana de Pares
ROA
-37.1%
-43.1%
ROE
-42.7%
-49.0%
Salud financiera Deuda, liquidez, solvencia — solidez del balance general
Métrica
Tendencia a 5 años
TYRA
Mediana de Pares
Current Ratio (Ratio corriente)
14.7
9.0
Quick Ratio (Ratio Rápido)
4.3
—
Crecimiento Crecimiento de ingresos, BPA y beneficio neto: interanual, CAGR a 3 años, CAGR a 5 años
Métrica
Tendencia a 5 años
TYRA
Mediana de Pares
Eficiencia de capital Rotación de activos, rotación de inventario, rotación de cuentas por cobrar
Métrica
Tendencia a 5 años
TYRA
Mediana de Pares
TYRA Consenso de analistas Opiniones de analistas alcistas y bajistas, precio objetivo a 12 meses, potencial alcista
COMPRA
22 analistas
- Compra fuerte 9 40,9%
- Compra 11 50,0%
- Mantener 2 9,1%
- Venta 0 0,0%
- Venta fuerte 0 0,0%
Precio objetivo a 12 meses
11 analistas · 2026-08-16
Mediana
$53.00
Media
$50.82
← Por Debajo de Todos los Objetivos
$26.42
Mín
$39.00
Máx
$59.00
Objetivo mediano
$53.00
+100,6%
Objetivo medio
$50.82
+92,3%
Historial de Ganancias EPS real vs estimado, sorpresa %, tasa de aciertos, próxima fecha de resultados
Sorpresa Media
0.00%
| Período | EPS Actual | EPS est. | Sorpresa |
|---|---|---|---|
| 30 de junio de 2026 | $-0.69 | $-0.66 | -0.03% |
| 31 de marzo de 2026 | $-0.64 | $-0.60 | -0.04% |
| 31 de diciembre de 2025 | $-0.57 | $-0.54 | -0.03% |
| 30 de septiembre de 2025 | $-0.50 | $-0.51 | 0.01% |
| 30 de junio de 2025 | $-0.47 | $-0.54 | 0.07% |
| 31 de marzo de 2025 | $-0.47 | $-0.50 | 0.03% |
Comparación de pares (subindustria GICS) Métricas clave frente a competidores del sector
| Ticker | Capitalización Bursátil | P/E | Ingresos interanuales | Margen Neto | ROE | Margen Bruto |
|---|---|---|---|---|---|---|
| TYRA | $1.41B | -13.1 | — | — | -42.7% | — |
| RXRX | $2.16B | -2.8 | 26.9% | -863.4% | -62.9% | — |
| FBRX | $353M | -5.8 | 106.6% | -2555.2% | -86.9% | — |
| ZYME | $1.97B | -24.4 | 38.9% | -76.6% | -26.9% | — |
| BCAX | $953M | -6.7 | — | — | -33.0% | — |
| XNCR | $1.10B | -12.3 | 13.7% | -73.2% | -14.0% | — |
| JBIO | $761M | -4.8 | — | — | -47.7% | — |
| TRAX | — | — | — | — | — | — |
| VIR | $841M | -1.9 | -7.6% | -638.9% | -51.1% | — |
| ABSI | $529M | -4.2 | -38.2% | -4113.7% | -63.5% | — |
| AVBP | $854M | -4.7 | — | — | -59.7% | — |
Fundamentales Completos Todas las métricas por año — estado de resultados, balance general, flujo de caja
Estado de resultados 12
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $103M | $80M | $63M | $43M | $21M | $7M | |
| SG&A Expense | $30M | $24M | $17M | $16M | $6M | $2M | |
| Operating Expenses | $133M | $104M | $80M | $59M | $26M | $9M | |
| Operating Income | $-133M | $-104M | $-80M | $-59M | $-26M | $-9M | |
| Other Non-op | $13M | $18M | $11M | $4M | $-6.0K | $-39.0K | |
| Income Tax | $0 | $0 | $0 | $2.0K | $1.0K | $1.0K | |
| Net Income | $-120M | $-86M | $-69M | $-55M | $-26M | $-9M | |
| EPS (Basic) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 | · | |
| EPS (Diluted) | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 | · | |
| Shares (Basic) | 59,602,328 | 57,217,746 | 42,704,876 | 41,883,904 | 13,780,546 | · | |
| Shares (Diluted) | 59,602,328 | 57,217,746 | 42,704,876 | 41,883,904 | 13,780,546 | · | |
| EBITDA | $-132M | $-104M | $-80M | $-59M | $-26M | · |
Balance general 19
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $77M | $92M | $58M | $251M | $302M | $15M | |
| Prepaid Expense | $9M | $6M | $8M | $6M | $2M | $57.0K | |
| Current Assets | $265M | $347M | $212M | $257M | $304M | $15M | |
| PP&E (Net) | $1M | $2M | $2M | $1M | $1M | $297.0K | |
| PP&E (Gross) | · | $3M | $2M | $2M | $1M | $340.0K | |
| Accum. Depreciation | · | $1M | $807.0K | $461.0K | $169.0K | $43.0K | |
| Other Non-current Assets | $9M | $7M | $5M | $4M | $312.0K | $21.0K | |
| Total Assets | $283M | $364M | $226M | $266M | $307M | $16M | |
| Accounts Payable | $1M | $590.0K | $5M | $1M | $599.0K | $664.0K | |
| Current Liabilities | $18M | $15M | $15M | $6M | $4M | $2M | |
| Capital Leases | $5M | $6M | $6M | $2M | $981.0K | $0 | |
| Other Non-current Liabilities | $0 | $3.0K | $46.0K | $169.0K | $367.0K | $140.0K | |
| Total Liabilities | $23M | $20M | $22M | $8M | $5M | $2M | |
| Common Stock | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $0 | |
| Retained Earnings | $-371M | $-251M | $-165M | $-96M | $-40M | $-14M | |
| AOCI | $393.0K | $770.0K | $381.0K | $0 | · | · | |
| Stockholders' Equity | $259M | $343M | $204M | $258M | $302M | $-14M | |
| Liabilities + Equity | $283M | $364M | $226M | $266M | $307M | $16M | |
| Shares Outstanding | 53,706,357 | 50,749,945 | 43,024,634 | 42,353,550 | 41,441,135 | 1,829,377 |
Flujo de Efectivo 9
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| D&A | $546.0K | $519.0K | $357.0K | $296.0K | $140.0K | $47.0K | |
| Stock-based Comp | $28M | $23M | $14M | $11M | $3M | $439.0K | |
| Other Non-cash | $-4M | $-7M | $5M | $-6M | $-478.0K | · | |
| Operating Cash Flow | $-95M | $-70M | $-50M | $-50M | $-24M | $-8M | |
| CapEx | $141.0K | $664.0K | $770.0K | $559.0K | $661.0K | $312.0K | |
| Investing Cash Flow | $72M | $-98M | $-145M | $-559.0K | $-645.0K | $-312.0K | |
| Financing Cash Flow | $8M | $202M | $2M | $632.0K | $311M | $23M | |
| Net Change in Cash | $-15M | $34M | $-193M | $-50M | $287M | $15M | |
| Free Cash Flow | $-95M | $-70M | $-51M | $-51M | $-24M | · |
Rentabilidad 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -37.1% | -29.3% | -28.1% | -19.3% | -16.3% | · | |
| ROE | -42.7% | -24.5% | -32.4% | -21.1% | -8.6% | · |
Liquidez y Solvencia 2
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 14.7 | 23.8 | 13.8 | 45.1 | 84.1 | · | |
| Quick Ratio | 4.3 | 6.3 | 3.8 | 44.1 | 83.6 | · |
Valoración (TTM) 8
| Métrica | Tendencia | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-120M | $-86M | $-69M | $-55M | $-26M | · | |
| Market Cap | $1.41B | $705M | $596M | $322M | $583M | · | |
| P/E | -13.1 | -9.2 | -8.5 | -5.8 | -7.4 | · | |
| P/B | 5.4 | 2.1 | 2.9 | 1.2 | 1.9 | · | |
| P / Tangible Book | 5.4 | 2.1 | 2.9 | 1.2 | 1.9 | · | |
| P / Cash Flow | -14.8 | -10.1 | -11.9 | -6.4 | -24.6 | · | |
| P / FCF | -14.8 | -10.0 | -11.7 | -6.3 | -23.9 | · | |
| Earnings Yield | -7.6% | -10.9% | -11.7% | -17.4% | -13.6% | · |
Estado de resultados 11
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $39M | $33M | $28M | $25M | $24M | $25M | $22M | $23M | $18M | $17M | $21M | $19M | $12M | $10M | $10M | $11M | |
| SG&A Expense | $10M | $9M | $8M | $7M | $7M | $7M | $8M | $6M | $6M | $5M | $5M | $5M | $4M | $4M | $10M | $173.0K | |
| Operating Expenses | $49M | $42M | $37M | $33M | $31M | $32M | $30M | $29M | $24M | $22M | $26M | $24M | $16M | $14M | $15M | $14M | |
| Operating Income | $-49M | $-42M | $-37M | $-33M | $-31M | $-32M | $-30M | $-29M | $-24M | $-22M | $-26M | $-24M | $-16M | $-14M | $-15M | $-14M | |
| Other Non-op | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $5M | $5M | $4M | $3M | $3M | $3M | $2M | $3M | $5.0K | |
| Net Income | $-46M | $-39M | $-34M | $-30M | $-28M | $-28M | $-26M | $-24M | $-19M | $-18M | $-23M | $-21M | $-13M | $-12M | $-13M | $-13M | |
| EPS (Basic) | $-0.69 | $-0.64 | $-0.57 | $-0.50 | $-0.47 | $-0.47 | $-0.43 | $-0.41 | $-0.32 | $-0.35 | $-0.54 | $-0.49 | $-0.31 | $-0.28 | $-0.30 | $-0.30 | |
| EPS (Diluted) | $-0.69 | $-0.64 | $-0.57 | $-0.50 | $-0.47 | $-0.47 | $-0.43 | $-0.41 | $-0.32 | $-0.35 | $-0.54 | $-0.49 | $-0.31 | $-0.28 | $-0.30 | $-0.30 | |
| Shares (Basic) | 65,991,171 | 61,746,050 | -118,955,750 | 59,670,757 | 59,550,771 | 59,336,550 | -112,554,397 | 58,874,497 | 58,668,712 | 52,228,934 | -85,147,300 | 42,868,340 | 42,589,213 | 42,394,623 | -83,442,210 | 41,997,195 | |
| Shares (Diluted) | 65,991,171 | 61,746,050 | -118,955,750 | 59,670,757 | 59,550,771 | 59,336,550 | -112,554,397 | 58,874,497 | 58,668,712 | 52,228,934 | -85,147,300 | 42,868,340 | 42,589,213 | 42,394,623 | -83,442,210 | 41,997,195 | |
| EBITDA | $-49M | $-42M | · | $-33M | $-31M | $-32M | · | $-29M | $-24M | $-22M | · | $-24M | $-16M | $-14M | · | $-14M |
Balance general 19
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $74M | $85M | $77M | $62M | $98M | $101M | $92M | $104M | $99M | $254M | $58M | $216M | $232M | $242M | $251M | $263M | |
| Prepaid Expense | $13M | $11M | $9M | $6M | $6M | $6M | $6M | $5M | $5M | $8M | $8M | $9M | $8M | $5M | $6M | $4M | |
| Current Assets | $367M | $395M | $265M | $281M | $302M | $325M | $347M | $366M | $379M | $391M | $212M | $225M | $241M | $247M | $257M | $267M | |
| PP&E (Net) | $1M | $1M | $1M | $1M | $1M | $2M | $2M | $2M | $2M | $2M | $2M | $1M | $1M | $1M | $1M | $1M | |
| PP&E (Gross) | · | · | · | · | · | $3M | · | $3M | $3M | $3M | $2M | $2M | $2M | $2M | $2M | $2M | |
| Accum. Depreciation | · | · | · | · | · | $1M | · | $1M | $1M | $926.0K | $807.0K | $706.0K | $629.0K | $544.0K | $461.0K | $379.0K | |
| Other Non-current Assets | $9M | $10M | $9M | $13M | $11M | $10M | $7M | $6M | $5M | $5M | $5M | $5M | $866.0K | $4M | $4M | $4M | |
| Total Assets | $383M | $412M | $283M | $302M | $321M | $343M | $364M | $381M | $392M | $405M | $226M | $238M | $250M | $255M | $266M | $276M | |
| Accounts Payable | $2M | $4M | $1M | $2M | $2M | $2M | $590.0K | $1M | $2M | $3M | $5M | $2M | $1M | $1M | $1M | $3M | |
| Current Liabilities | $25M | $19M | $18M | $16M | $14M | $14M | $15M | $12M | $10M | $9M | $15M | $10M | $5M | $4M | $6M | $5M | |
| Capital Leases | $5M | $5M | $5M | $5M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $6M | $2M | $2M | $3M | |
| Other Non-current Liabilities | · | · | $0 | $0 | $0 | $0 | $3.0K | $11.0K | $20.0K | $29.0K | $46.0K | $77.0K | $108.0K | $139.0K | $169.0K | $226.0K | |
| Total Liabilities | $30M | $24M | $23M | $21M | $19M | $20M | $20M | $18M | $16M | $15M | $22M | $16M | $11M | $6M | $8M | $8M | |
| Common Stock | $6.0K | $6.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $5.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | $4.0K | |
| Retained Earnings | $-456M | $-411M | $-371M | $-337M | $-308M | $-279M | $-251M | $-226M | $-202M | $-183M | $-165M | $-142M | $-121M | $-108M | $-96M | $-83M | |
| AOCI | $-580.0K | $107.0K | $393.0K | $442.0K | $436.0K | $688.0K | $770.0K | $2M | $-184.0K | $-6.0K | $381.0K | · | · | · | $0 | · | |
| Stockholders' Equity | $354M | $388M | $259M | $281M | $302M | $324M | $343M | $362M | $376M | $390M | $204M | $222M | $239M | $249M | $258M | $268M | |
| Liabilities + Equity | $383M | $412M | $283M | $302M | $321M | $343M | $364M | $381M | $392M | $405M | $226M | $238M | $250M | $255M | $266M | $276M | |
| Shares Outstanding | 59,662,877 | 59,469,687 | 53,706,357 | 53,318,198 | 53,233,494 | 53,089,957 | 50,749,945 | 52,871,825 | 52,736,458 | 52,474,533 | 43,024,634 | 42,928,884 | 42,817,233 | 42,535,374 | 42,353,550 | 42,136,971 |
Flujo de Efectivo 11
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D&A | $138.0K | $138.0K | $132.0K | $131.0K | $140.0K | $143.0K | $144.0K | $127.0K | $126.0K | $122.0K | $102.0K | $86.0K | $89.0K | $83.0K | $82.0K | $82.0K | |
| Stock-based Comp | $10M | $8M | $8M | $8M | $6M | $6M | $7M | $8M | $4M | $4M | $4M | $4M | $3M | $2M | $3M | $1M | |
| Other Non-cash | · | $-1M | · | · | · | $-4M | · | · | · | $-8M | · | · | · | $-483.0K | · | · | |
| Operating Cash Flow | $-31M | $-33M | $-24M | $-22M | $-24M | $-25M | $-20M | $-18M | $-10M | $-22M | $-14M | $-17M | $-10M | $-10M | $-12M | $-12M | |
| CapEx | $66.0K | $88.0K | $57.0K | $39.0K | $31.0K | $14.0K | $6.0K | $52.0K | $470.0K | $136.0K | $603.0K | $83.0K | $43.0K | $41.0K | $21.0K | $48.0K | |
| Investing Cash Flow | $18M | $-120M | $34M | $-15M | $21M | $32M | $7M | $22M | $-145M | $18M | $-144M | $-83.0K | $-43.0K | $-41.0K | $-21.0K | $-48.0K | |
| Stock Issued | $0 | $148M | · | · | $0 | $0 | · | · | · | · | · | · | · | · | · | · | |
| Net Stock Activity | · | $148M | · | · | · | · | · | · | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $2M | $160M | $5M | $647.0K | $583.0K | $2M | $706.0K | $743.0K | $373.0K | $200M | $324.0K | $467.0K | $370.0K | $376.0K | $3.0K | $364.0K | |
| Net Change in Cash | $-11M | $8M | $15M | $-37M | $-2M | $9M | $-12M | $4M | $-155M | $196M | $-158M | $-17M | $-9M | $-10M | $-12M | $-12M | |
| Free Cash Flow | · | $-33M | · | · | · | $-25M | · | · | · | $-22M | · | · | · | $-10M | · | · |
Rentabilidad 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -12.9% | -10.4% | · | -8.8% | -7.9% | -7.5% | · | -7.8% | -5.8% | -5.5% | · | -8.2% | -4.9% | -4.3% | · | -4.2% | |
| ROE | -13.9% | -11.1% | · | -9.3% | -8.3% | -7.9% | · | -8.2% | -6.1% | -5.7% | · | -8.6% | -5.1% | -4.4% | · | -4.3% |
Liquidez y Solvencia 2
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 14.9 | 20.5 | · | 17.7 | 21.9 | 22.8 | · | 29.5 | 36.5 | 44.8 | · | 22.1 | 44.5 | 67.0 | · | 48.7 | |
| Quick Ratio | 3.0 | 4.4 | · | 3.9 | 7.2 | 7.1 | · | 8.4 | 9.6 | 29.2 | · | 21.3 | 43.0 | 65.6 | · | 48.0 |
Valoración (TTM) 8
| Métrica | Tendencia | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q4 2023 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-143M | $-125M | · | $-110M | $-99M | $-89M | · | $-82M | $-71M | $-64M | · | $-59M | $-53M | $-54M | · | $-49M | |
| Market Cap | $1.91B | $2.28B | · | $746M | $509M | $494M | · | $1.24B | $843M | $861M | · | $591M | $729M | $684M | · | $370M | |
| P/E | -13.9 | -18.4 | · | -7.6 | -5.7 | -6.0 | · | -15.0 | -10.9 | -11.5 | · | -10.0 | -13.6 | -12.4 | · | -5.1 | |
| P/B | 5.4 | 5.9 | · | 2.7 | 1.7 | 1.5 | · | 3.4 | 2.2 | 2.2 | · | 2.7 | 3.1 | 2.7 | · | 1.4 | |
| P / Tangible Book | 5.4 | 5.9 | · | 2.7 | 1.7 | 1.5 | · | 3.4 | 2.2 | 2.2 | · | 2.7 | 3.1 | 2.7 | · | 1.4 | |
| P / Cash Flow | · | -69.9 | · | · | · | -19.4 | · | · | · | -39.1 | · | · | · | -69.4 | · | · | |
| P / FCF | · | -69.7 | · | · | · | -19.4 | · | · | · | -38.8 | · | · | · | -69.1 | · | · | |
| Earnings Yield | -7.2% | -5.4% | · | -13.2% | -17.4% | -16.7% | · | -6.7% | -9.2% | -8.7% | · | -10.0% | -7.3% | -8.1% | · | -19.8% |
Estados Financieros Estado de resultados, balance general, flujo de caja — anual, últimos 5 años
Estado de resultados
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Beneficio neto | $-120M | $-86M | $-69M | $-55M | $-26M |
| EPS Diluido | $-2.01 | $-1.51 | $-1.62 | $-1.32 | $-1.91 |
Balance general
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Ratio corriente | 14.7 | 23.8 | 13.8 | 45.1 | 84.1 |
| Ratio Rápido | 4.3 | 6.3 | 3.8 | 44.1 | 83.6 |
Flujo de Efectivo
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flujo de caja libre | $-95M | $-70M | $-51M | $-51M | $-24M |
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Propietarios institucionales (13F) 182 declarantes · $1.9B total · A fecha de 30 de junio de 2026
Instituciones que informan tener esta acción en su Formulario 13F trimestral de la SEC. Solo posiciones largas; un solo presentador puede aparecer dos veces para tramos de opciones separados. Las patas de put/call de compensación grandes suelen reflejar la creación de mercado o el inventario cubierto, no la convicción direccional.
Actividad institucional — Q2 2026 vs trimestre anterior
| Nuevas posiciones | Posiciones cerradas | Aumentado | Disminuido | Cambio neto de acciones |
|---|---|---|---|---|
| 41 (-9 vs trimestre anterior) | 22 (+9 vs trimestre anterior) | 60 (+8 vs trimestre anterior) | 49 (+12 vs trimestre anterior) | +7.7M |
Comparado con Q1 2026. Las presentaciones del Formulario 13F de la SEC vencen dentro de los 45 días posteriores al final del trimestre, más un pequeño margen para los presentadores tardíos; los trimestres que aún se encuentran dentro de esa ventana se omiten en favor del par más reciente completamente reportado.
| Institución | Valor | Acciones | % de 13F rastreadas | Tipo |
|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | $389 624 083 | 12 198 625 | 20,33% | Acciones |
| FMR LLC | $259 465 452 | 8 123 527 | 13,54% | Acciones |
| Alta Partners Management Company, L.P. | $122 120 195 | 3 823 425 | 6,37% | Acciones |
| Nextech Invest Ltd. | $113 501 505 | 3 553 585 | 5,92% | Acciones |
| TCG Crossover Management, LLC | $103 772 421 | 3 248 980 | 5,42% | Acciones |
| STATE STREET CORP | $68 363 354 | 2 140 368 | 3,57% | Acciones |
| Commodore Capital LP | $59 887 500 | 1 875 000 | 3,13% | Acciones |
| Paradigm Biocapital Advisors LP | $58 405 708 | 1 828 607 | 3,05% | Acciones |
| Nextech Invest Ltd. | $56 376 468 | 4 055 861 | 2,94% | Acciones |
| VANGUARD CAPITAL MANAGEMENT LLC | $48 179 797 | 1 508 447 | 2,51% | Acciones |
| BVF INC/IL | $47 149 700 | 1 476 196 | 2,46% | Acciones |
| VANGUARD GROUP INC | $36 938 081 | 1 405 024 | 1,93% | Acciones |
| 5AM Venture Management, LLC | $32 875 778 | 1 029 298 | 1,72% | Acciones |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $32 482 980 | 1 017 000 | 1,70% | Acciones |
| Hood River Capital Management LLC | $32 475 794 | 1 016 775 | 1,69% | Acciones |
| GEODE CAPITAL MANAGEMENT, LLC | $27 157 539 | 850 108 | 1,42% | Acciones |
| Caligan Partners LP | $25 775 133 | 806 986 | 1,34% | Acciones |
| Canaan Partners XI LLC | $23 955 000 | 750 000 | 1,25% | Acciones |
| Siren, L.L.C. | $23 156 500 | 725 000 | 1,21% | Acciones |
| Sio Capital Management, LLC | $22 208 361 | 695 315 | 1,16% | Acciones |
| STEMPOINT CAPITAL LP | $20 210 163 | 632 754 | 1,05% | Acciones |
| MARSHALL WACE, LLP | $18 625 268 | 583 133 | 0,97% | Acciones |
| JENNISON ASSOCIATES LLC | $14 403 791 | 450 964 | 0,75% | Acciones |
| TWO SIGMA INVESTMENTS, LP | $14 366 868 | 449 808 | 0,75% | Acciones |
| GOLDMAN SACHS GROUP INC | $13 394 997 | 419 380 | 0,70% | Acciones |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $12 872 427 | 403 019 | 0,67% | Acciones |
| Defilade Capital Management, L.P. | $12 037 228 | 376 870 | 0,63% | Acciones |
| Walleye Capital LLC | $11 111 862 | 347 898 | 0,58% | Acciones |
| Woodline Partners LP | $10 222 078 | 320 040 | 0,53% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $9 086 930 | 284 500 | 0,47% | Opción de compra |
| BANK OF AMERICA CORP /DE/ | $8 955 529 | 280 386 | 0,47% | Acciones |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $8 550 306 | 267 699 | 0,45% | Acciones |
| Qube Research & Technologies Ltd | $8 525 872 | 266 934 | 0,44% | Acciones |
| BNP PARIBAS FINANCIAL MARKETS | $7 672 850 | 240 227 | 0,40% | Acciones |
| ALGERT GLOBAL LLC | $7 637 493 | 239 120 | 0,40% | Acciones |
| VANGUARD FIDUCIARY TRUST CO | $7 180 272 | 224 805 | 0,37% | Acciones |
| DIMENSIONAL FUND ADVISORS LP | $6 691 686 | 209 508 | 0,35% | Acciones |
| Affinity Asset Advisors, LLC | $6 388 383 | 200 012 | 0,33% | Acciones |
| FRANKLIN RESOURCES INC | $6 143 340 | 192 340 | 0,32% | Acciones |
| HighVista Strategies LLC | $5 901 681 | 184 774 | 0,31% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $5 674 844 | 177 672 | 0,30% | Acciones |
| CITADEL ADVISORS LLC | $5 581 036 | 174 735 | 0,29% | Acciones |
| BOOTHBAY FUND MANAGEMENT, LLC | $5 543 474 | 173 559 | 0,29% | Acciones |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $5 174 280 | 162 000 | 0,27% | Acciones |
| Jump Financial, LLC | $5 014 580 | 157 000 | 0,26% | Acciones |
| VICTORY CAPITAL MANAGEMENT INC | $4 873 565 | 152 585 | 0,25% | Acciones |
| Ensign Peak Advisors, Inc | $4 680 392 | 146 537 | 0,24% | Acciones |
| Trexquant Investment LP | $4 239 716 | 132 740 | 0,22% | Acciones |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $3 931 495 | 123 090 | 0,21% | Acciones |
| BARCLAYS PLC | $3 631 578 | 113 700 | 0,19% | Opción de compra |
| ORBIMED ADVISORS LLC | $3 257 880 | 102 000 | 0,17% | Acciones |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $2 849 208 | 89 205 | 0,15% | Acciones |
| JANUS HENDERSON GROUP PLC | $2 711 816 | 70 814 | 0,14% | Acciones |
| OPPENHEIMER & CO INC | $2 676 029 | 83 783 | 0,14% | Acciones |
| XTX Topco Ltd | $2 597 361 | 81 320 | 0,14% | Acciones |
| Kalehua Capital Management LLC | $2 378 412 | 74 465 | 0,12% | Acciones |
| RAYMOND JAMES FINANCIAL INC | $2 177 094 | 68 162 | 0,11% | Acciones |
| SEI INVESTMENTS CO | $2 127 428 | 66 607 | 0,11% | Acciones |
| Squarepoint Ops LLC | $2 037 932 | 63 805 | 0,11% | Acciones |
| Fisher Asset Management, LLC | $1 923 745 | 60 230 | 0,10% | Acciones |
| ALPS ADVISORS INC | $1 921 478 | 60 159 | 0,10% | Acciones |
| CITIGROUP INC | $1 921 383 | 60 156 | 0,10% | Acciones |
| ALLIANCEBERNSTEIN L.P. | $1 854 486 | 48 420 | 0,10% | Acciones |
| AXA Investment Managers S.A. | $1 801 758 | 128 789 | 0,09% | Acciones |
| RHUMBLINE ADVISERS | $1 662 114 | 52 039 | 0,09% | Acciones |
| TD Asset Management Inc | $1 597 000 | 50 000 | 0,08% | Acciones |
| Arkadios Wealth Advisors | $1 575 792 | 49 336 | 0,08% | Acciones |
| TWO SIGMA ADVISERS, LP | $1 548 481 | 58 900 | 0,08% | Acciones |
| STATE OF WISCONSIN INVESTMENT BOARD | $1 491 502 | 46 697 | 0,08% | Acciones |
| JANE STREET GROUP, LLC | $1 437 300 | 45 000 | 0,08% | Opción de venta |
| Susquehanna Portfolio Strategies, LLC | $1 433 403 | 44 878 | 0,07% | Acciones |
| Swiss National Bank | $1 427 718 | 44 700 | 0,07% | Acciones |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1 415 804 | 44 327 | 0,07% | Acciones |
| ExodusPoint Capital Management, LP | $1 310 370 | 41 026 | 0,07% | Acciones |
| Rafferty Asset Management, LLC | $1 236 142 | 38 702 | 0,06% | Acciones |
| Bank of New York Mellon Corp | $1 224 612 | 38 341 | 0,06% | Acciones |
| Verdad Advisers, LP | $1 149 936 | 36 003 | 0,06% | Acciones |
| WELLS FARGO & COMPANY/MN | $1 071 938 | 33 561 | 0,06% | Acciones |
| Sofinnova Investments, Inc. | $1 030 608 | 32 267 | 0,05% | Acciones |
| Engineers Gate Manager LP | $1 020 739 | 31 958 | 0,05% | Acciones |
| BlackRock, Inc. | $841 236 | 26 338 | 0,04% | Acciones |
| PDT Partners, LLC | $820 347 | 25 684 | 0,04% | Acciones |
| MILLENNIUM MANAGEMENT LLC | $798 500 | 25 000 | 0,04% | Opción de compra |
| STRS OHIO | $705 874 | 22 100 | 0,04% | Acciones |
| MetLife Investment Management, LLC | $693 833 | 21 723 | 0,04% | Acciones |
| LMR Partners LLP | $675 563 | 21 151 | 0,04% | Acciones |
| Auour Investments LLC | $671 379 | 21 020 | 0,04% | Acciones |
| Vanguard Global Advisers, LLC | $643 719 | 20 154 | 0,03% | Acciones |
| Elmind Capital, LP | $638 800 | 20 000 | 0,03% | Acciones |
| PROFUND ADVISORS LLC | $625 641 | 19 588 | 0,03% | Acciones |
| WELLINGTON MANAGEMENT GROUP LLP | $594 467 | 18 612 | 0,03% | Acciones |
| Cubist Systematic Strategies, LLC | $549 946 | 39 310 | 0,03% | Acciones |
| AMERIPRISE FINANCIAL INC | $540 425 | 16 920 | 0,03% | Acciones |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $538 764 | 16 868 | 0,03% | Acciones |
| WINTON GROUP Ltd | $536 592 | 16 800 | 0,03% | Acciones |
| VANGUARD ASSET MANAGEMENT, Ltd | $494 399 | 15 479 | 0,03% | Acciones |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $479 100 | 15 000 | 0,03% | Opción de venta |
| Invesco Ltd. | $463 897 | 14 524 | 0,02% | Acciones |
| FOX RUN MANAGEMENT, L.L.C. | $461 533 | 14 450 | 0,02% | Acciones |
| NEW YORK STATE COMMON RETIREMENT FUND | $412 761 | 12 923 | 0,02% | Acciones |
Informantes de la empresa 24 insiders · 12 directivos · 12 consejeros
| Insider | Rol | Última actividad | Acciones en propiedad | Compras 12m | Ventas 12m | Neto 12m |
|---|---|---|---|---|---|---|
| Todd Harris | President and CEO | 5 de mayo de 2026 A | 1 437 631 | 0 | 0 | $0 |
| Alan Fuhrman | Chief Financial Officer | 5 de mayo de 2026 A | 36 164 | 0 | 0 | $0 |
| Esther Van Den Boom | Chief Financial Officer | 15 de septiembre de 2022 A | 121 897 | 0 | 0 | $0 |
| Bhavesh Ashar | Chief Operating Officer | 5 de mayo de 2026 A | 15 013 | 0 | 0 | $0 |
| Yuliya Rueb | Vice President, Finance (PAO) | 5 de mayo de 2026 A | 43 354 | 0 | 0 | $0 |
| Douglas J Warner | Chief Medical Officer | 5 de mayo de 2026 A | 25 000 | 0 | 0 | $0 |
| Daniel Bensen | Chief Discovery Officer | 12 de febrero de 2026 S | 146 981 | 0 | 11 | $-4 811 405 |
| Hiroomi Tada | Chief Medical Officer | 15 de marzo de 2024 A | 86 435 | 0 | 0 | $0 |
| Patel Piyush R. | Chief Development Officer | 21 de febrero de 2023 G | 73 794 | 0 | 0 | $0 |
| Robert L. Hudkins | Chief Technology Officer | 15 de septiembre de 2022 A | 273 576 | 0 | 0 | $0 |
| Ronald V. Swanson | Chief Scientific Officer | 6 de septiembre de 2022 A | 273 254 | 0 | 0 | $0 |
| Ali D. Fawaz | General Counsel and Secretary | 16 de mayo de 2022 A | — | 0 | 0 | $0 |
| Habib J Dable | Consejero | 16 de abril de 2026 A | — | 0 | 0 | $0 |
| Gilla Kaplan | Consejero | 26 de marzo de 2026 M | 28 231 | 0 | 1 | $-528 486 |
| Robert J More | Consejero | 19 de diciembre de 2025 S | 3 823 425 | 0 | 2 | $-5 249 138 |
| Stephen Michael Rothenberg | Consejero | 29 de mayo de 2025 A | — | 0 | 0 | $0 |
| Rehan Verjee | Consejero | 29 de mayo de 2025 A | — | 0 | 0 | $0 |
| Susan Moran | Consejero | 29 de mayo de 2025 A | — | 0 | 0 | $0 |
| Nina S Kjellson | Consejero | 5 de febrero de 2025 S | 443 885 | 0 | 0 | $0 |
| Adele M. Gulfo | Consejero | 29 de enero de 2025 A | — | 0 | 0 | $0 |
| Siddarth Subramony | Consejero | 29 de mayo de 2024 A | — | 0 | 0 | $0 |
| Jake Simson | Consejero | 29 de mayo de 2024 A | — | 0 | 0 | $0 |
| Isan Chen | Consejero | 31 de mayo de 2023 A | 192 783 | 0 | 0 | $0 |
| Boxer Capital Management, LLC | — | 18 de octubre de 2024 A | 4 448 359 | 0 | 0 | $0 |
Informantes de las presentaciones SEC Form 3/4/5; neto = solo P/S de mercado abierto
Activistas y propietarios del %+ 5 5 tenencias
Inversores que presentaron el Anexo 13D de la SEC — propiedad beneficiosa superior al % 5 con la intención de influir en el emisor (participaciones activistas, campañas de la junta directiva, M&A). Cada fila muestra el estado conocido más reciente de la posición de ese declarante.
| Declarante | Presentado | Participación | Estado | Propósito | Presentación |
|---|---|---|---|---|---|
| RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, RA Capital Healthcare Fund, L.P. ×7 presentaciones | 6 de marzo de 2026 | 21,20% | Enmienda | — | SEC |
| MVA Investors, LLC, Aaron I. Davis, Boxer Capital Management, LLC ×3 presentaciones | 6 de diciembre de 2024 | — | Presentación inicial | — | SEC |
| Boxer Asset Management Inc, Joe Lewis | 15 de octubre de 2024 | — | Presentación inicial | — | SEC |
| Boxer Capital, LLC, MVA Investors, LLC, Aaron I. Davis, Boxer Capital Management, LLC, Siddarth Subramony ×4 presentaciones | 15 de octubre de 2024 | — | Presentación inicial | — | SEC |
| Alta Partners NextGen Fund II, L.P., Alta Partners NextGen Fund II Management, LLC, Peter Hudson, Daniel Janney, Robert More | 27 de septiembre de 2021 | — | Presentación inicial | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Propiedad de ETFs Mantenido por 42 ETFs
El peso refleja solo las tenencias directas de acciones (N-PORT); los fondos apalancados o basados en derivados pueden tener exposición adicional a swaps no mostrada.
| Fondo | Ponderación | Unidades | A fecha de | Fuente |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1,15% | 55 509 NS | 31 de mayo de 2026 | N-PORT |
| BBC · ETFis Series Trust I | 1,14% | 12 196 NS | 30 de abril de 2026 | N-PORT |
| CANC · Tema ETF Trust | 0,30% | 15 780 NS | 31 de mayo de 2026 | N-PORT |
| ESSC · Strategy Shares | 0,25% | 1 876 NS | 30 de abril de 2026 | N-PORT |
| LABU · Direxion Shares ETF Trust | 0,25% | 37 514 NS | 30 de abril de 2026 | N-PORT |
| VFMO · VANGUARD WELLINGTON FUND | 0,13% | 81 594 SH | 8 de agosto de 2026 | Diario |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,11% | 3 239 SH | 8 de agosto de 2026 | Diario |
| IBB · iShares Trust | 0,09% | 325 051 SH | 8 de agosto de 2026 | Diario |
| BIB · ProShares Trust | 0,09% | 1 974 NS | 31 de mayo de 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,09% | 33 120 NS | 30 de abril de 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,07% | 39 429 SH | 8 de agosto de 2026 | Diario |
| IWO · iShares Trust | 0,06% | 331 311 SH | 8 de agosto de 2026 | Diario |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,04% | 211 804 SH | 8 de agosto de 2026 | Diario |
| SMMV · iShares Trust | 0,04% | 4 107 SH | 8 de agosto de 2026 | Diario |
| IWM · iShares Trust | 0,03% | 933 036 SH | 8 de agosto de 2026 | Diario |
| RSSL · Global X Funds | 0,03% | 11 184 NS | 30 de abril de 2026 | N-PORT |
| GSSC · Goldman Sachs ETF Trust | 0,02% | 7 291 NS | 31 de mayo de 2026 | N-PORT |
| ITWO · ProShares Trust | 0,02% | 1 219 NS | 31 de mayo de 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,02% | 114 471 NS | 31 de mayo de 2026 | N-PORT |
| OMFS · Invesco Exchange-Traded Self-Indexe… | 0,02% | 1 805 SH | 8 de agosto de 2026 | Diario |
| UWM · ProShares Trust | 0,01% | 954 NS | 31 de mayo de 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,01% | 340 900 SH | 8 de agosto de 2026 | Diario |
| VHT · VANGUARD WORLD FUND | 0,01% | 67 148 SH | 8 de agosto de 2026 | Diario |
| URTY · ProShares Trust | 0,01% | 967 NS | 31 de mayo de 2026 | N-PORT |
| FHLC · FIDELITY COVINGTON TRUST | 0,01% | 6 122 NS | 30 de abril de 2026 | N-PORT |
| ISCV · iShares Trust | 0,01% | 1 827 SH | 8 de agosto de 2026 | Diario |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 18 052 NS | 31 de mayo de 2026 | N-PORT |
| ISCB · iShares Trust | 0,01% | 583 SH | 8 de agosto de 2026 | Diario |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,00% | 1 002 NS | 31 de mayo de 2026 | N-PORT |
| ISCG · iShares Trust | 0,00% | 1 509 SH | 8 de agosto de 2026 | Diario |
| WSML · iShares Trust | 0,00% | 955 SH | 8 de agosto de 2026 | Diario |
| HDG · ProShares Trust | 0,00% | 24 NS | 31 de mayo de 2026 | N-PORT |
| DFAS · Dimensional ETF Trust | 0,00% | 12 741 NS | 30 de abril de 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 46 810 SH | 8 de agosto de 2026 | Diario |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 13 115 NS | 31 de mayo de 2026 | N-PORT |
| IWV · iShares Trust | 0,00% | 6 606 SH | 8 de agosto de 2026 | Diario |
| DCOR · Dimensional ETF Trust | 0,00% | 548 NS | 30 de abril de 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 1 440 NS | 30 de abril de 2026 | N-PORT |
| DFAU · Dimensional ETF Trust | 0,00% | 682 NS | 30 de abril de 2026 | N-PORT |
| AVSU · AMERICAN CENTURY ETF TRUST | 0,00% | 10 NS | 31 de mayo de 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,00% | 1 135 472 SH | 8 de agosto de 2026 | Diario |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 3 044 SH | 8 de agosto de 2026 | Diario |