BIOA — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| a16z Capital Management, L.L.C. | $79 244 997 | 3 233 170 | 8,37% | Actions |
| BlackRock, Inc. | $69 830 877 | 2 849 077 | 7,38% | Actions |
| Cormorant Asset Management, LP | $58 593 729 | 2 390 605 | 6,19% | Actions |
| Sofinnova Investments, Inc. | $56 220 744 | 2 293 788 | 5,94% | Actions |
| Octagon Capital Advisors LP | $42 843 480 | 1 748 000 | 4,53% | Actions |
| RA CAPITAL MANAGEMENT, L.P. | $40 972 092 | 1 671 648 | 4,33% | Actions |
| MPM BIOIMPACT LLC | $40 874 371 | 1 667 661 | 4,32% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $37 848 685 | 1 544 214 | 4,00% | Actions |
| JANUS HENDERSON GROUP PLC | $36 597 368 | 2 094 270 | 3,87% | Actions |
| Polar Capital Holdings Plc | $26 283 151 | 1 072 344 | 2,78% | Actions |
| BRAIDWELL LP | $25 321 992 | 1 033 129 | 2,67% | Actions |
| STATE STREET CORP | $25 036 083 | 1 021 464 | 2,64% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $24 619 235 | 1 004 264 | 2,60% | Actions |
| Sands Capital Alternatives, LLC | $19 273 512 | 786 353 | 2,04% | Actions |
| VANGUARD GROUP INC | $18 717 407 | 1 414 770 | 1,98% | Actions |
| ORBIMED ADVISORS LLC | $18 435 270 | 752 153 | 1,95% | Actions |
| D. E. Shaw & Co., Inc. | $18 205 072 | 742 761 | 1,92% | Actions |
| Balyasny Asset Management L.P. | $17 227 050 | 702 858 | 1,82% | Actions |
| Pivotal bioVenture Partners Investment Advisor LLC | $16 014 197 | 653 374 | 1,69% | Actions |
| COSMIC MANAGEMENT, LLC | $12 299 927 | 501 833 | 1,30% | Actions |
| STEMPOINT CAPITAL LP | $11 376 831 | 464 171 | 1,20% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $10 053 144 | 410 165 | 1,06% | Actions |
| DIMENSIONAL FUND ADVISORS LP | $9 661 958 | 394 138 | 1,02% | Actions |
| JACOBS LEVY EQUITY MANAGEMENT, INC | $9 242 353 | 377 085 | 0,98% | Actions |
| Walleye Capital LLC | $8 686 221 | 354 395 | 0,92% | Actions |
| Nuveen, LLC | $8 557 471 | 349 142 | 0,90% | Actions |
| NORTHERN TRUST CORP | $8 410 999 | 343 166 | 0,89% | Actions |
| Integral Health Asset Management, LLC | $7 353 000 | 300 000 | 0,78% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $7 353 000 | 300 000 | 0,78% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $7 267 215 | 296 500 | 0,77% | Option d'achat |
| MORGAN STANLEY | $6 921 282 | 282 386 | 0,73% | Actions |
| FRANKLIN RESOURCES INC | $6 911 011 | 281 967 | 0,73% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $6 700 323 | 273 371 | 0,71% | Actions |
| Comprehensive Financial Management LLC | $6 662 847 | 271 842 | 0,70% | Actions |
| GOLDMAN SACHS GROUP INC | $6 636 548 | 270 769 | 0,70% | Actions |
| BANK OF AMERICA CORP /DE/ | $6 320 026 | 257 855 | 0,67% | Actions |
| Squadron Capital Management LLC | $6 127 500 | 250 000 | 0,65% | Option d'achat |
| JPMORGAN CHASE & CO | $5 837 776 | 233 979 | 0,62% | Actions |
| MILLENNIUM MANAGEMENT LLC | $5 456 441 | 222 621 | 0,58% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $5 382 396 | 219 600 | 0,57% | Actions |
| SPHERA FUNDS MANAGEMENT LTD. | $5 237 076 | 213 671 | 0,55% | Actions |
| DIADEMA PARTNERS LP | $4 904 451 | 200 100 | 0,52% | Option d'achat |
| Ikarian Capital, LLC | $4 901 999 | 200 000 | 0,52% | Actions |
| FMR LLC | $4 499 129 | 183 563 | 0,48% | Actions |
| Yiheng Capital Management, L.P. | $4 179 739 | 170 532 | 0,44% | Actions |
| RENAISSANCE TECHNOLOGIES LLC | $4 061 307 | 165 700 | 0,43% | Actions |
| Squadron Capital Management LLC | $3 799 050 | 155 000 | 0,40% | Actions |
| DIADEMA PARTNERS LP | $3 586 646 | 146 334 | 0,38% | Actions |
| Ensign Peak Advisors, Inc | $3 473 018 | 141 698 | 0,37% | Actions |
| Invesco Ltd. | $3 123 064 | 127 420 | 0,33% | Actions |
| Bank of New York Mellon Corp | $2 630 698 | 107 332 | 0,28% | Actions |
| UBS Group AG | $2 522 716 | 102 926 | 0,27% | Actions |
| NEXTBio Capital Management LP | $2 468 941 | 100 732 | 0,26% | Actions |
| Burkehill Global Management, LP | $2 451 000 | 100 000 | 0,26% | Actions |
| WELLINGTON MANAGEMENT GROUP LLP | $2 320 018 | 94 656 | 0,25% | Actions |
| Alessandra Capital Management, LLC | $2 288 459 | 93 368 | 0,24% | Actions |
| Russell Investments Group, Ltd. | $1 941 112 | 79 196 | 0,21% | Actions |
| CITADEL ADVISORS LLC | $1 920 726 | 78 365 | 0,20% | Actions |
| Caption Management, LLC | $1 838 250 | 75 000 | 0,19% | Option d'achat |
| BNP PARIBAS FINANCIAL MARKETS | $1 752 146 | 71 487 | 0,19% | Actions |
| Birchview Capital, LP | $1 691 190 | 69 000 | 0,18% | Actions |
| Squarepoint Ops LLC | $1 677 366 | 68 436 | 0,18% | Actions |
| TWO SIGMA INVESTMENTS, LP | $1 504 767 | 61 394 | 0,16% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $1 504 424 | 61 380 | 0,16% | Actions |
| AMERIPRISE FINANCIAL INC | $1 450 943 | 59 198 | 0,15% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 431 384 | 58 400 | 0,15% | Option de vente |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 422 193 | 58 025 | 0,15% | Actions |
| AMERICAN CENTURY COMPANIES INC | $1 342 658 | 54 780 | 0,14% | Actions |
| AQR CAPITAL MANAGEMENT LLC | $1 254 618 | 51 188 | 0,13% | Actions |
| Quantinno Capital Management LP | $1 254 618 | 51 188 | 0,13% | Actions |
| SEVEN GRAND MANAGERS, LLC | $1 225 500 | 50 000 | 0,13% | Actions |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $1 214 348 | 49 545 | 0,13% | Actions |
| Moody Aldrich Partners LLC | $1 164 004 | 47 491 | 0,12% | Actions |
| SIMPLEX TRADING, LLC | $1 158 832 | 47 280 | 0,12% | Actions |
| RHUMBLINE ADVISERS | $1 076 080 | 43 904 | 0,11% | Actions |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | $1 029 420 | 42 000 | 0,11% | Actions |
| Corient Private Wealth LP | $986 724 | 40 258 | 0,10% | Actions |
| Persistent Asset Partners Ltd | $913 071 | 37 253 | 0,10% | Actions |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $866 183 | 35 340 | 0,09% | Actions |
| DEUTSCHE BANK AG\ | $840 644 | 34 298 | 0,09% | Actions |
| ALLIANCEBERNSTEIN L.P. | $799 293 | 45 700 | 0,08% | Actions |
| CITADEL ADVISORS LLC | $794 124 | 32 400 | 0,08% | Option de vente |
| Militia Capital Management LLC | $791 330 | 32 286 | 0,08% | Actions |
| Vanguard Global Advisers, LLC | $781 011 | 31 865 | 0,08% | Actions |
| MARSHALL WACE, LLP | $778 021 | 31 743 | 0,08% | Actions |
| CITIGROUP INC | $746 869 | 30 472 | 0,08% | Actions |
| WELLS FARGO & COMPANY/MN | $727 800 | 29 694 | 0,08% | Actions |
| STATE OF WISCONSIN INVESTMENT BOARD | $689 883 | 28 147 | 0,07% | Actions |
| CITADEL ADVISORS LLC | $681 378 | 27 800 | 0,07% | Option d'achat |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | $681 084 | 27 788 | 0,07% | Actions |
| XTX Topco Ltd | $656 696 | 26 793 | 0,07% | Actions |
| WEXFORD CAPITAL LP | $631 500 | 25 765 | 0,07% | Actions |
| BARCLAYS PLC | $627 947 | 25 620 | 0,07% | Actions |
| MILLENNIUM MANAGEMENT LLC | $612 750 | 25 000 | 0,06% | Option d'achat |
| JANE STREET GROUP, LLC | $590 421 | 24 089 | 0,06% | Actions |
| Caption Management, LLC | $569 612 | 23 240 | 0,06% | Actions |
| STRS OHIO | $539 220 | 22 000 | 0,06% | Actions |
| Militia Capital Partners, LP | $533 169 | 40 300 | 0,06% | Actions |
| MetLife Investment Management, LLC | $511 989 | 20 889 | 0,05% | Actions |
| Stonepine Capital Management, LLC | $490 200 | 20 000 | 0,05% | Actions |
| BANK OF NOVA SCOTIA | $490 200 | 20 000 | 0,05% | Actions |
| Creative Planning | $454 292 | 18 535 | 0,05% | Actions |
| Man Group plc | $444 783 | 18 147 | 0,05% | Actions |
| Virtus Investment Advisers, LLC | $444 538 | 18 137 | 0,05% | Actions |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | $443 386 | 18 090 | 0,05% | Actions |
| Verdad Advisers, LP | $426 327 | 17 394 | 0,05% | Actions |
| JANE STREET GROUP, LLC | $409 317 | 16 700 | 0,04% | Option de vente |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $396 743 | 16 187 | 0,04% | Actions |
| GREAT LAKES ADVISORS, LLC | $390 493 | 15 932 | 0,04% | Actions |
| Y-Intercept (Hong Kong) Ltd | $373 532 | 15 240 | 0,04% | Actions |
| Engineers Gate Manager LP | $343 508 | 14 015 | 0,04% | Actions |
| Persistent Asset Partners Ltd | $342 710 | 510 | 0,04% | Option d'achat |
| JANE STREET GROUP, LLC | $335 787 | 13 700 | 0,04% | Option d'achat |
| Valor Management LLC | $321 204 | 13 105 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $303 924 | 12 400 | 0,03% | Actions |
| NISA INVESTMENT ADVISORS, LLC | $293 556 | 11 977 | 0,03% | Actions |
| GLENMEDE TRUST CO NA | $268 629 | 10 960 | 0,03% | Actions |
| PROFUND ADVISORS LLC | $266 669 | 10 880 | 0,03% | Actions |
| TWO SIGMA ADVISERS, LP | $257 985 | 19 500 | 0,03% | Actions |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | $256 669 | 10 472 | 0,03% | Actions |
| Police & Firemen's Retirement System of New Jersey | $254 095 | 10 367 | 0,03% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $233 556 | 9 529 | 0,02% | Actions |
| Quadrature Capital Ltd | $232 355 | 9 480 | 0,02% | Actions |
| RWA WEALTH PARTNERS, LLC | $222 820 | 9 091 | 0,02% | Actions |
| China Universal Asset Management Co., Ltd. | $173 408 | 7 075 | 0,02% | Actions |
| State of Wyoming | $153 776 | 6 274 | 0,02% | Actions |
| Legal & General Group Plc | $83 653 | 3 413 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $78 530 | 3 204 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $78 187 | 3 190 | 0,01% | Actions |
| CWM, LLC | $64 328 | 3 678 | 0,01% | Actions |
| Zurcher Kantonalbank (Zurich Cantonalbank) | $51 397 | 2 097 | 0,01% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $48 726 | 1 988 | 0,01% | Actions |
| PNC Financial Services Group, Inc. | $48 382 | 1 974 | 0,01% | Actions |
| US BANCORP \DE\ | $32 132 | 1 311 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $26 000 | 1 070 | 0,00% | Actions |
| SIGNATUREFD, LLC | $24 682 | 1 007 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $22 574 | 921 | 0,00% | Actions |
| Parallel Advisors, LLC | $21 250 | 867 | 0,00% | Actions |
| Sterling Capital Management LLC | $15 956 | 651 | 0,00% | Actions |
| Arax Advisory Partners | $13 284 | 542 | 0,00% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $10 368 | 423 | 0,00% | Actions |
| TD Waterhouse Canada Inc. | $6 212 | 256 | 0,00% | Actions |
| ACADIAN ASSET MANAGEMENT LLC | $5 499 | 224 453 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $4 484 | 183 | 0,00% | Actions |
| Torren Management, LLC | $3 725 | 213 | 0,00% | Actions |
| EverSource Wealth Advisors, LLC | $3 555 | 145 | 0,00% | Actions |
| Farther Finance Advisors, LLC | $3 304 | 133 | 0,00% | Actions |
| Steward Partners Investment Advisory, LLC | $3 137 | 128 | 0,00% | Actions |
| NATIONAL BANK OF CANADA /FI/ | $3 064 | 125 | 0,00% | Actions |
| Truvestments Capital LLC | $2 917 | 119 | 0,00% | Actions |
| Cornerstone Financial Management LLC | $2 696 | 110 | 0,00% | Actions |
| Essential Partners LLC | $2 353 | 96 | 0,00% | Actions |
| GROUP ONE TRADING LLC | $2 353 | 96 | 0,00% | Actions |
| MassMutual Private Wealth & Trust, FSB | $2 328 | 95 | 0,00% | Actions |
| Cornerstone Planning Group LLC | $2 238 | 102 | 0,00% | Actions |
| ROTHSCHILD INVESTMENT LLC | $2 132 | 87 | 0,00% | Actions |
| True Wealth Design, LLC | $1 961 | 80 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $717 | 29 247 | 0,00% | Actions |
| Silver Grove Financial Group, Inc. | $368 | 15 | 0,00% | Actions |
| FIFTH THIRD BANCORP | $270 | 11 | 0,00% | Actions |
| GAMMA Investing LLC | $221 | 9 | 0,00% | Actions |
| IFP Advisors, Inc | $221 | 9 | 0,00% | Actions |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $122 | 7 | 0,00% | Actions |
| Allworth Financial LP | $99 | 4 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $98 | 4 | 0,00% | Actions |
| Sunbelt Securities, Inc. | $52 | 3 | 0,00% | Actions |