GHRS — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Lynx1 Capital Management LP | $356 517 181 | 13 263 288 | 25,76% | Actions |
| BVF INC/IL | $232 516 247 | 8 650 158 | 16,80% | Actions |
| RA CAPITAL MANAGEMENT, L.P. | $205 277 533 | 7 636 813 | 14,83% | Actions |
| FMR LLC | $160 662 969 | 5 977 045 | 11,61% | Actions |
| RTW INVESTMENTS, LP | $159 500 947 | 5 933 815 | 11,52% | Actions |
| Deep Track Capital, LP | $89 600 018 | 3 333 334 | 6,47% | Actions |
| Avoro Capital Advisors LLC | $48 384 000 | 1 800 000 | 3,50% | Actions |
| Foresite Capital Management VI LLC | $25 280 452 | 940 493 | 1,83% | Actions |
| Jefferies Financial Group Inc. | $19 146 624 | 712 300 | 1,38% | Actions |
| BlackRock, Inc. | $12 910 116 | 480 287 | 0,93% | Actions |
| UBS Group AG | $12 832 727 | 477 408 | 0,93% | Actions |
| MILLENNIUM MANAGEMENT LLC | $8 692 965 | 323 399 | 0,63% | Actions |
| BRAIDWELL LP | $5 570 611 | 207 240 | 0,40% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $5 432 529 | 202 103 | 0,39% | Actions |
| JANE STREET GROUP, LLC | $4 568 283 | 169 951 | 0,33% | Actions |
| HighVista Strategies LLC | $4 267 737 | 158 770 | 0,31% | Actions |
| Trexquant Investment LP | $4 133 257 | 153 767 | 0,30% | Actions |
| GOLDMAN SACHS GROUP INC | $3 996 330 | 148 673 | 0,29% | Actions |
| XTX Topco Ltd | $2 338 184 | 86 986 | 0,17% | Actions |
| CITADEL ADVISORS LLC | $2 310 390 | 85 952 | 0,17% | Actions |
| AdvisorShares Investments LLC | $1 915 657 | 71 267 | 0,14% | Actions |
| CenterBook Partners LP | $1 866 440 | 69 436 | 0,13% | Actions |
| MORGAN STANLEY | $1 403 620 | 52 218 | 0,10% | Actions |
| Point72 Asset Management, L.P. | $1 367 708 | 50 882 | 0,10% | Actions |
| MARSHALL WACE, LLP | $1 255 215 | 46 697 | 0,09% | Actions |
| Qube Research & Technologies Ltd | $1 181 322 | 43 948 | 0,09% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $1 088 183 | 40 483 | 0,08% | Actions |
| TUDOR INVESTMENT CORP ET AL | $921 393 | 34 278 | 0,07% | Actions |
| NORTHERN TRUST CORP | $855 967 | 31 844 | 0,06% | Actions |
| JANE STREET GROUP, LLC | $787 584 | 29 300 | 0,06% | Option d'achat |
| D. E. Shaw & Co., Inc. | $681 274 | 25 345 | 0,05% | Actions |
| Quadrature Capital Ltd | $567 625 | 21 117 | 0,04% | Actions |
| JPMORGAN CHASE & CO | $534 985 | 18 778 | 0,04% | Actions |
| CITADEL ADVISORS LLC | $532 224 | 19 800 | 0,04% | Option d'achat |
| Squarepoint Ops LLC | $495 398 | 18 430 | 0,04% | Actions |
| Virtus Investment Advisers, LLC | $416 425 | 15 492 | 0,03% | Actions |
| LETKO, BROSSEAU & ASSOCIATES INC | $414 624 | 15 425 | 0,03% | Actions |
| China Universal Asset Management Co., Ltd. | $360 703 | 13 419 | 0,03% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $360 192 | 13 400 | 0,03% | Option d'achat |
| JANE STREET GROUP, LLC | $360 192 | 13 400 | 0,03% | Option de vente |
| HighTower Advisors, LLC | $341 376 | 12 700 | 0,02% | Actions |
| Cubist Systematic Strategies, LLC | $325 068 | 22 732 | 0,02% | Actions |
| STATE STREET CORP | $300 061 | 11 163 | 0,02% | Actions |
| Lion Point Capital, LP | $274 176 | 10 200 | 0,02% | Actions |
| Eversept Partners, LP | $233 103 | 8 672 | 0,02% | Actions |
| HSBC HOLDINGS PLC | $216 420 | 7 847 | 0,02% | Actions |
| BARCLAYS PLC | $160 661 | 5 977 | 0,01% | Actions |
| ROYAL BANK OF CANADA | $158 000 | 5 877 | 0,01% | Actions |
| OSAIC HOLDINGS, INC. | $155 232 | 5 775 | 0,01% | Actions |
| SIMPLEX TRADING, LLC | $127 384 | 4 739 | 0,01% | Actions |
| Mirae Asset Global Investments Co., Ltd. | $82 468 | 3 068 | 0,01% | Actions |
| North Star Investment Management Corp. | $59 136 | 2 200 | 0,00% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $45 615 | 1 697 | 0,00% | Actions |
| CITIGROUP INC | $43 384 | 1 614 | 0,00% | Actions |
| GF FUND MANAGEMENT CO. LTD. | $35 347 | 1 315 | 0,00% | Actions |
| WELLS FARGO & COMPANY/MN | $33 600 | 1 250 | 0,00% | Actions |
| JONES FINANCIAL COMPANIES LLLP | $21 871 | 775 | 0,00% | Actions |
| HARBOUR INVESTMENTS, INC. | $21 504 | 800 | 0,00% | Actions |
| Tower Research Capital LLC (TRC) | $13 843 | 515 | 0,00% | Actions |
| SBI Securities Co., Ltd. | $11 048 | 411 | 0,00% | Actions |
| HOLLENCREST CAPITAL MANAGEMENT | $6 720 | 250 | 0,00% | Actions |
| Federation des caisses Desjardins du Quebec | $5 510 | 205 | 0,00% | Actions |
| Farther Finance Advisors, LLC | $2 688 | 100 | 0,00% | Actions |
| HRT FINANCIAL LP | $1 757 | 65 375 | 0,00% | Actions |
| Cornerstone Financial Management LLC | $860 | 32 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $511 | 19 | 0,00% | Actions |