IVA — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Caligan Partners LP | $30 856 862 | 8 163 191 | 9,39% | Actions |
| SAMSARA BIOCAPITAL, LLC | $23 869 963 | 6 314 805 | 7,26% | Actions |
| Paradigm Biocapital Advisors LP | $15 120 000 | 4 000 000 | 4,60% | Actions |
| ANDERA PARTNERS | $13 733 424 | 3 633 181 | 4,18% | Actions |
| ADAR1 Capital Management, LLC | $13 633 160 | 3 606 656 | 4,15% | Actions |
| MILLENNIUM MANAGEMENT LLC | $13 276 018 | 3 512 174 | 4,04% | Actions |
| SymBiosis Capital Partners, LLC | $13 064 700 | 2 354 000 | 3,98% | Actions |
| Nantahala Capital Management, LLC | $10 154 566 | 2 686 393 | 3,09% | Actions |
| Trails Edge Capital Partners, LP | $10 047 228 | 2 657 997 | 3,06% | Actions |
| FRANKLIN RESOURCES INC | $9 989 070 | 2 642 611 | 3,04% | Actions |
| Squadron Capital Management LLC | $9 204 300 | 2 435 000 | 2,80% | Actions |
| Woodline Partners LP | $8 781 503 | 2 323 149 | 2,67% | Actions |
| Aberdeen Group plc | $8 723 382 | 2 307 773 | 2,65% | Actions |
| UBS Group AG | $8 713 626 | 2 305 192 | 2,65% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $7 574 296 | 2 003 782 | 2,30% | Actions |
| Patient Square Capital LP | $7 435 906 | 1 967 171 | 2,26% | Actions |
| NEXTBio Capital Management LP | $6 758 580 | 1 787 984 | 2,06% | Actions |
| CITADEL ADVISORS LLC | $6 745 659 | 1 784 566 | 2,05% | Actions |
| AMERIPRISE FINANCIAL INC | $6 415 219 | 1 697 148 | 1,95% | Actions |
| Point72 Asset Management, L.P. | $6 361 785 | 1 683 012 | 1,94% | Actions |
| Integral Health Asset Management, LLC | $5 745 600 | 1 520 000 | 1,75% | Actions |
| Yu Fan | $5 670 000 | 1 500 000 | 1,73% | Actions |
| NEA Management Company, LLC | $5 528 575 | 1 462 586 | 1,68% | Actions |
| STEMPOINT CAPITAL LP | $5 391 490 | 1 426 320 | 1,64% | Actions |
| Propel Bio Management, LLC | $4 842 981 | 1 281 212 | 1,47% | Actions |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $4 800 600 | 1 270 000 | 1,46% | Actions |
| JPMORGAN CHASE & CO | $4 647 305 | 1 309 100 | 1,41% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4 233 600 | 1 120 000 | 1,29% | Actions |
| Ikarian Capital, LLC | $4 152 521 | 1 129 101 | 1,26% | Actions |
| Polar Capital Holdings Plc | $4 060 529 | 1 074 214 | 1,24% | Actions |
| MARSHALL WACE, LLP | $3 651 131 | 965 907 | 1,11% | Actions |
| Alyeska Investment Group, L.P. | $3 436 020 | 909 000 | 1,05% | Actions |
| MORGAN STANLEY | $3 408 199 | 901 640 | 1,04% | Actions |
| JANE STREET GROUP, LLC | $3 407 175 | 901 369 | 1,04% | Actions |
| HighVista Strategies LLC | $3 142 851 | 831 442 | 0,96% | Actions |
| Deep Track Capital, LP | $3 024 000 | 800 000 | 0,92% | Actions |
| TWO SIGMA INVESTMENTS, LP | $2 752 260 | 728 111 | 0,84% | Actions |
| DIADEMA PARTNERS LP | $2 725 718 | 740 786 | 0,83% | Actions |
| BVF INC/IL | $2 593 231 | 686 040 | 0,79% | Actions |
| FMR LLC | $2 590 812 | 685 400 | 0,79% | Actions |
| Ally Bridge Group (NY) LLC | $2 399 544 | 634 800 | 0,73% | Actions |
| Qube Research & Technologies Ltd | $1 502 769 | 397 558 | 0,46% | Actions |
| J. Goldman & Co LP | $1 275 750 | 337 500 | 0,39% | Actions |
| Simplify Asset Management Inc. | $1 184 966 | 313 483 | 0,36% | Actions |
| Artisan Partners Limited Partnership | $996 174 | 263 538 | 0,30% | Actions |
| Ghisallo Capital Management LLC | $945 000 | 250 000 | 0,29% | Actions |
| Burkehill Global Management, LP | $850 500 | 225 000 | 0,26% | Actions |
| SEVEN GRAND MANAGERS, LLC | $850 500 | 225 000 | 0,26% | Actions |
| GOLDMAN SACHS GROUP INC | $848 606 | 224 499 | 0,26% | Actions |
| XTX Topco Ltd | $809 986 | 214 282 | 0,25% | Actions |
| Persistent Asset Partners Ltd | $790 708 | 209 182 | 0,24% | Actions |
| Quadrature Capital Ltd | $783 148 | 207 182 | 0,24% | Actions |
| Seven Fleet Capital Management LP | $756 533 | 200 141 | 0,23% | Actions |
| BANK OF AMERICA CORP /DE/ | $574 247 | 151 917 | 0,17% | Actions |
| Balyasny Asset Management L.P. | $545 004 | 144 181 | 0,17% | Actions |
| Walleye Capital LLC | $512 749 | 135 648 | 0,16% | Actions |
| Hudson Bay Capital Management LP | $434 700 | 115 000 | 0,13% | Actions |
| Rathbones Group PLC | $378 000 | 100 000 | 0,12% | Actions |
| COMMONWEALTH EQUITY SERVICES, LLC | $317 500 | 83 996 | 0,10% | Actions |
| Engineers Gate Manager LP | $268 818 | 71 116 | 0,08% | Actions |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | $157 922 | 36 726 | 0,05% | Actions |
| Jefferies Financial Group Inc. | $151 200 | 40 000 | 0,05% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $129 861 | 34 355 | 0,04% | Actions |
| R Squared Ltd | $113 090 | 29 918 | 0,03% | Actions |
| Quaker Wealth Management, LLC | $94 349 | 24 960 | 0,03% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $92 485 | 24 467 | 0,03% | Actions |
| Shay Capital LLC | $82 672 | 21 871 | 0,03% | Actions |
| China Universal Asset Management Co., Ltd. | $81 648 | 21 600 | 0,02% | Actions |
| NewEdge Advisors, LLC | $75 895 | 20 078 | 0,02% | Actions |
| Cerity Partners LLC | $75 600 | 20 000 | 0,02% | Actions |
| ROYAL BANK OF CANADA | $60 000 | 15 741 | 0,02% | Actions |
| Ground Swell Capital, LLC | $48 395 | 12 803 | 0,01% | Actions |
| BLAIR WILLIAM & CO/IL | $37 800 | 10 000 | 0,01% | Actions |
| Frec Markets, Inc. | $37 800 | 10 000 | 0,01% | Actions |
| CITIGROUP INC | $24 993 | 6 612 | 0,01% | Actions |
| GAMMA Investing LLC | $18 976 | 5 020 | 0,01% | Actions |
| RHUMBLINE ADVISERS | $17 656 | 4 672 | 0,01% | Actions |
| Tower Research Capital LLC (TRC) | $6 804 | 1 800 | 0,00% | Actions |
| BARCLAYS PLC | $6 732 | 1 781 | 0,00% | Actions |
| Stone House Investment Management, LLC | $5 530 | 1 463 | 0,00% | Actions |
| SYQUANT CAPITAL SAS | $3 452 | 913 135 | 0,00% | Actions |
| OSAIC HOLDINGS, INC. | $1 164 | 308 | 0,00% | Actions |
| Atlantic Union Bankshares Corp | $1 134 | 300 | 0,00% | Actions |
| Larson Financial Group LLC | $851 | 225 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $586 | 155 | 0,00% | Actions |
| HRT FINANCIAL LP | $468 | 123 953 | 0,00% | Actions |
| Bell Investment Advisors, Inc | $288 | 76 | 0,00% | Actions |
| Arax Advisory Partners | $193 | 51 | 0,00% | Actions |
| Covestor Ltd | $2 | 402 | 0,00% | Actions |