SABS — Détenteurs institutionnels (13F)
Institutions qui déclarent détenir cette action dans leur Formulaire SEC 13F trimestriel. Uniquement les positions longues ; un même déclarant peut apparaître deux fois pour des jambes d'options distinctes. Les jambes put/call compensatoires importantes reflètent généralement la tenue de marché ou un inventaire couvert, pas une conviction directionnelle.
| Institution | Valeur | Actions | % de 13F suivies | Type |
|---|---|---|---|---|
| Caligan Partners LP | $31 072 107 | 7 967 207 | 11,30% | Actions |
| Vivo Capital, LLC | $28 469 645 | 7 299 909 | 10,35% | Actions |
| PERCEPTIVE ADVISORS LLC | $25 847 254 | 6 627 501 | 9,40% | Actions |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $24 981 657 | 6 405 553 | 9,09% | Actions |
| RA CAPITAL MANAGEMENT, L.P. | $17 165 850 | 4 401 500 | 6,24% | Actions |
| Balyasny Asset Management L.P. | $14 665 712 | 3 760 439 | 5,33% | Actions |
| BlackRock, Inc. | $11 957 462 | 3 066 016 | 4,35% | Actions |
| VANGUARD CAPITAL MANAGEMENT LLC | $11 594 423 | 2 972 929 | 4,22% | Actions |
| Commodore Capital LP | $11 193 000 | 2 870 000 | 4,07% | Actions |
| MILLENNIUM MANAGEMENT LLC | $10 721 439 | 2 749 087 | 3,90% | Actions |
| Spruce Street Capital LP | $8 574 158 | 2 198 502 | 3,12% | Actions |
| Sessa Capital IM, L.P. | $8 573 982 | 2 198 457 | 3,12% | Actions |
| VANGUARD GROUP INC | $6 908 288 | 1 847 136 | 2,51% | Actions |
| Affinity Asset Advisors, LLC | $5 947 500 | 1 525 000 | 2,16% | Actions |
| BOOTHBAY FUND MANAGEMENT, LLC | $5 778 474 | 1 481 660 | 2,10% | Actions |
| GEODE CAPITAL MANAGEMENT, LLC | $4 981 704 | 1 277 185 | 1,81% | Actions |
| Woodline Partners LP | $4 603 385 | 1 180 355 | 1,67% | Actions |
| Ensign Peak Advisors, Inc | $4 573 300 | 1 172 641 | 1,66% | Actions |
| Propel Bio Management, LLC | $4 198 654 | 1 076 578 | 1,53% | Actions |
| Soleus Capital Management, L.P. | $3 510 000 | 900 000 | 1,28% | Actions |
| Seven Fleet Capital Management LP | $2 870 700 | 736 077 | 1,04% | Actions |
| AMERIPRISE FINANCIAL INC | $2 382 975 | 611 019 | 0,87% | Actions |
| STATE STREET CORP | $2 070 241 | 530 831 | 0,75% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1 710 209 | 438 515 | 0,62% | Actions |
| DV EQUITIES, LLC | $1 560 000 | 400 000 | 0,57% | Actions |
| AWM Investment Company, Inc. | $1 462 500 | 375 000 | 0,53% | Actions |
| VANGUARD FIDUCIARY TRUST CO | $1 458 522 | 373 980 | 0,53% | Actions |
| UBS Group AG | $1 426 924 | 365 878 | 0,52% | Actions |
| NORTHERN TRUST CORP | $1 413 707 | 362 489 | 0,51% | Actions |
| STEMPOINT CAPITAL LP | $1 336 261 | 342 631 | 0,49% | Actions |
| HB Wealth Management, LLC | $1 199 250 | 307 500 | 0,44% | Actions |
| Polymer Capital Management (HK) LTD | $1 195 666 | 306 581 | 0,43% | Actions |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1 141 639 | 292 728 | 0,42% | Actions |
| JANE STREET GROUP, LLC | $883 350 | 226 500 | 0,32% | Option de vente |
| TWO SIGMA INVESTMENTS, LP | $837 065 | 214 632 | 0,30% | Actions |
| GOLDMAN SACHS GROUP INC | $746 089 | 191 305 | 0,27% | Actions |
| Bank of New York Mellon Corp | $420 604 | 107 847 | 0,15% | Actions |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $412 160 | 105 682 | 0,15% | Actions |
| Simplify Asset Management Inc. | $408 911 | 104 849 | 0,15% | Actions |
| AMERICAN CENTURY COMPANIES INC | $330 271 | 84 685 | 0,12% | Actions |
| CITADEL ADVISORS LLC | $315 900 | 81 000 | 0,11% | Option d'achat |
| ALPS ADVISORS INC | $302 640 | 77 600 | 0,11% | Actions |
| Stonepine Capital Management, LLC | $285 757 | 73 271 | 0,10% | Actions |
| CITADEL ADVISORS LLC | $244 908 | 62 797 | 0,09% | Actions |
| Nuveen, LLC | $227 752 | 58 398 | 0,08% | Actions |
| JANE STREET GROUP, LLC | $209 040 | 53 600 | 0,08% | Option d'achat |
| Pathstone Holdings, LLC | $197 537 | 50 650 | 0,07% | Actions |
| Kestra Advisory Services, LLC | $194 263 | 49 811 | 0,07% | Actions |
| RHUMBLINE ADVISERS | $176 133 | 45 164 | 0,06% | Actions |
| WELLS FARGO & COMPANY/MN | $171 924 | 44 083 | 0,06% | Actions |
| DEUTSCHE BANK AG\ | $165 247 | 42 371 | 0,06% | Actions |
| IFP Advisors, Inc | $150 926 | 38 699 | 0,05% | Actions |
| BARCLAYS PLC | $140 019 | 35 902 | 0,05% | Actions |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $110 760 | 28 400 | 0,04% | Option d'achat |
| MetLife Investment Management, LLC | $109 259 | 28 015 | 0,04% | Actions |
| ALLIANCEBERNSTEIN L.P. | $105 183 | 26 970 | 0,04% | Actions |
| CITIGROUP INC | $103 677 | 26 584 | 0,04% | Actions |
| Persistent Asset Partners Ltd | $99 060 | 25 400 | 0,04% | Actions |
| BANK OF AMERICA CORP /DE/ | $97 991 | 25 126 | 0,04% | Actions |
| Invesco Ltd. | $88 112 | 22 593 | 0,03% | Actions |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $77 984 | 19 996 | 0,03% | Actions |
| JPMORGAN CHASE & CO | $70 547 | 18 089 | 0,03% | Actions |
| Scientech Research LLC | $68 039 | 17 446 | 0,02% | Actions |
| Quadrature Capital Ltd | $59 261 | 15 195 | 0,02% | Actions |
| JANE STREET GROUP, LLC | $57 073 | 14 634 | 0,02% | Actions |
| MORGAN STANLEY | $53 624 | 13 750 | 0,02% | Actions |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $50 493 | 12 947 | 0,02% | Actions |
| NEW YORK STATE COMMON RETIREMENT FUND | $50 310 | 12 900 | 0,02% | Actions |
| Miller Capital Partners, Inc. | $50 193 | 12 870 | 0,02% | Actions |
| Police & Firemen's Retirement System of New Jersey | $49 947 | 12 807 | 0,02% | Actions |
| Vanguard Global Advisers, LLC | $46 223 | 11 852 | 0,02% | Actions |
| PNC Financial Services Group, Inc. | $40 053 | 10 270 | 0,01% | Actions |
| BNP PARIBAS FINANCIAL MARKETS | $33 669 | 8 633 | 0,01% | Actions |
| STRS OHIO | $33 150 | 8 500 | 0,01% | Actions |
| OSAIC HOLDINGS, INC. | $31 534 | 8 086 | 0,01% | Actions |
| Plante Moran Financial Advisors, LLC | $23 108 | 5 925 | 0,01% | Actions |
| Legal & General Group Plc | $16 470 | 4 223 | 0,01% | Actions |
| Ameritas Investment Partners, Inc. | $15 370 | 3 941 | 0,01% | Actions |
| Russell Investments Group, Ltd. | $13 540 | 3 472 | 0,00% | Actions |
| Tower Research Capital LLC (TRC) | $9 828 | 2 520 | 0,00% | Actions |
| Federation des caisses Desjardins du Quebec | $7 800 | 2 000 | 0,00% | Actions |
| GROUP ONE TRADING LLC | $7 223 | 1 852 | 0,00% | Actions |
| ROYAL BANK OF CANADA | $7 000 | 1 687 | 0,00% | Actions |
| Truvestments Capital LLC | $4 290 | 1 100 | 0,00% | Actions |
| Sterling Capital Management LLC | $3 413 | 875 | 0,00% | Actions |
| Caitong International Asset Management Co., Ltd | $2 894 | 742 | 0,00% | Actions |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2 332 | 598 | 0,00% | Actions |
| GS Investments, Inc. | $780 | 200 | 0,00% | Actions |
| FMR LLC | $452 | 116 | 0,00% | Actions |
| HARBOUR INVESTMENTS, INC. | $195 | 50 | 0,00% | Actions |
| PRICE T ROWE ASSOCIATES INC /MD/ | $139 | 35 620 | 0,00% | Actions |
| First PREMIER Bank | $74 | 18 986 | 0,00% | Actions |