LXRX Lexicon Pharmaceuticals, Inc. - Common Stock

NASDAQ · Pharmaceuticals · Lihat di SEC EDGAR ↗
$2,38
Harga · Agu 18, 2026
Fundamental per Agu 6, 2026

Tentang Lexicon Pharmaceuticals, Inc. - Common Stock Tinjauan perusahaan dari Wikipedia

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

Baca selengkapnya

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

The company's clinical drug candidates include sotagliflozin (LX4211) for the treatment of type 2 diabetes; LX1033 for the treatment of irritable bowel syndrome and other gastrointestinal disorders; telotristat ethyl (LX1032) for the treatment of the symptoms associated with carcinoid syndrome; and LX2931 for the treatment of autoimmune diseases, such as rheumatoid arthritis.

Company history

Lexicon Pharmaceuticals was founded in September 1995 as a biotech venture of Baylor College of Medicine. The company went public in April 2000 with $220 million initial public offerings. In June, 2001 Lexicon purchased a privately owned small chemical library synthesis company, Coelacanth Corporation in Princeton, New Jersey, which became the site for the company's small molecule and medicinal chemistry efforts. The company's original name was Lexicon Genetics Incorporated, but in 2007, the name changed to Lexicon Pharmaceuticals, Inc. to reflect a renewed focus on drug development.

The company initially focused on using gene knockout technology to define the function of genes. This effort complemented and benefited from the international effort to sequence the human and mouse genomes (see Human Genome Project). Using its proprietary gene trapping and gene targeting technologies, the company created A repository of genetically modified mouse embryonic stem cells, known as OmniBank, and established a large-scale mammalian knockout program to discover the physiological and behavioral functions of the most druggable mammalian genes. The information collected from this program is stored in the company's LexVision database, which contains almost 5,000 gene knockouts studied. Over the years, Lexicon evolved from a genomics company into a drug discovery and development company focused on discovering and developing treatments for human disease. The company currently has multiple drug candidates in various stages of clinical trials.

In 2016, the company was ranked #8 on the Deloitte Fast 500 North America list.

Technology

Lexicon uses patented gene trapping and gene targeting technologies to generate and study knockout mice to discover the physiological and behavioral effects that result from the disruption of a single gene knockout. Because there is a close similarity in gene function and physiology between mice and humans, with a large majority of human genes having a counterpart in the mouse genome, knockout mouse technology has become a powerful tool in the discovery of new medicines.

The value of Lexicon's technology in drug discovery has been described in a retrospective analysis by the scientific journal Nature. The conclusion of this analysis was that, in most cases, there was a direct correlation when comparing the physiological characteristics, or phenotypes, of knockout mice to the therapeutic effect of the 100 best-selling drugs of 2001. The tremendous utility of knockout mouse technology was recognized in 2007 with the Nobel Prize in Physiology or Medicine to Drs. Mario Capecchi, Martin Evans, and Oliver Smithies.

In developing small molecule drugs for its validated targets, Lexicon uses medicinal chemistry known as "click chemistry." Dr. K. Barry Sharpless, who was awarded the 2001 Nobel Prize in Chemistry, developed this tools for the rapid synthesis of novel compounds. Lexicon uses solution-phase chemistry to generate diverse libraries of optically pure compounds that are built using organic reactions that allow the company to generate collections of diffrent compounds and to tailor the compound collections to address various therapeutic target families. Lexicon's medicinal chemists design these libraries by analyzing the chemical structures of drugs that have been proven safe and effective against human disease and using that knowledge in the design of scaffolds and chemical building blocks for the generation of large numbers of new drug-like compounds.

Locations

Lexicon operates from two locations found in Texas and New Jersey. The corporate headquarters are in The Woodlands, Texas just north of Houston. This location serves as Lexicon's primary research facility to discover and validate the company's drug targets and test drug candidates in preclinical research. The company's clinical development and regulatory team is also based at the corporate headquarters.

Lexicon's campus in Princeton, New Jersey is the home of Lexicon's small molecule medicinal chemistry and preclinical development efforts. This site serves as Lexicon's primary medicinal chemistry site to create new chemical entities for therapeutic development.

== References ==

Sumber: Wikipedia (English), CC BY-SA 4.0 · Lihat di Wikipedia ↗

Wikidata ↗

LXRX Cuplikan Saham Harga, kapitalisasi pasar, P/E, EPS, ROE, utang/ekuitas, kisaran 52 minggu

Harga
$2.38
Kapitalisasi Pasar
$869M
P/E (TTM)
-17.0
EPS (TTM)
$-0.14
Pendapatan (TTM)
$50M
Imbal Hasil Dividen
ROE
-39.7%
D/E Utang/Ekuitas
0.5
Rentang 52M
$1 – $3

LXRX Grafik Harga Saham OHLCV harian dengan indikator teknis — geser, perbesar, dan sesuaikan tampilan Anda

Kinerja 10 Tahun Tren Pendapatan, laba bersih, margin, dan EPS

Pendapatan & Laba Bersih $50M
10-point trend, -37.2%
2016-12-31 2025-12-31
EPS $-0.14
9-point trend, +88.0%
2017-12-31 2025-12-31
Arus Kas Bebas $-68M
10-point trend, +61.4%
2016-12-31 2025-12-31
Margin -101.1%

Valuasi Rasio P/E, P/S, P/B, EV/EBITDA — apakah sahamnya mahal atau murah?

Metrik
Tren 5 Tahun
LXRX
Median Rekan
P/E (TTM)
5-point trend, -25.1%
-17.0
29.9
P/S (TTM)
5-point trend, +514.6%
17.4
14.4
P/B
5-point trend, +3.5%
8.1
4.4
EV / EBITDA
5-point trend, +1.2%
-17.1
Price / FCF (Harga / FCF)
5-point trend, -259.3%
-12.8

Profitabilitas Margin kotor, operasional, dan bersih; ROE, ROA, ROIC

Metrik
Tren 5 Tahun
LXRX
Median Rekan
Operating Margin (Margin Operasi)
5-point trend, +99.7%
-98.2%
Net Profit Margin (Margin Laba Bersih)
5-point trend, +99.7%
-101.1%
0.70%
ROA
5-point trend, +59.6%
-20.8%
-0.55%
ROE
5-point trend, +38.9%
-39.7%
-2.5%

Kesehatan Keuangan Utang, likuiditas, solvabilitas — kekuatan neraca

Metrik
Tren 5 Tahun
LXRX
Median Rekan
Debt / Equity (Utang / Ekuitas)
5-point trend, +574.1%
0.5
Current Ratio (Rasio Lancar)
5-point trend, +21.5%
4.9
3.9
Quick Ratio (Rasio Cepat)
5-point trend, +20.5%
4.7

Pertumbuhan Pertumbuhan Pendapatan, EPS, dan Laba Bersih: YoY, CAGR 3T, CAGR 5T

Metrik
Tren 5 Tahun
LXRX
Median Rekan
Revenue YoY (Pendapatan YoY)
5-point trend, +16612.4%
60.2%
Revenue CAGR 3Y (CAGR Pendapatan 3T)
5-point trend, +16612.4%
610.2%
Revenue CAGR 5Y (CAGR Pendapatan 5T)
5-point trend, +16612.4%
15.7%

Metrik Per Saham EPS, nilai buku per saham, arus kas per saham, dividen per saham

Metrik
Tren 5 Tahun
LXRX
Median Rekan
EPS (Diluted)
5-point trend, +76.7%
$-0.14

Efisiensi Modal Perputaran aset, perputaran persediaan, perputaran piutang

Metrik
Tren 5 Tahun
LXRX
Median Rekan

LXRX Konsensus Analis Opini analis bullish dan bearish, target harga 12 bulan, potensi kenaikan

BELI 11 analis
  • Beli Kuat 3 27,3%
  • Beli 5 45,5%
  • Tahan 3 27,3%
  • Jual 0 0,0%
  • Jual Kuat 0 0,0%

Target Harga 12 Bulan

5 analis · 2026-08-19
Target median $3.10 +30,5%
Target rata-rata $3.86 +62,4%

Riwayat Pendapatan EPS aktual vs perkiraan, kejutan %, tingkat keberhasilan, tanggal pendapatan berikutnya

Kejutan Rata-rata
0.03%
Periode EPS Aktual EPS Estimasi Kejutan
30 Juni 2026 $-0.07 $-0.05 -0.02%
31 Maret 2026 $0.00 $-0.04 0.04%
31 Des. 2025 $-0.04 $-0.07 0.03%
30 Sep. 2025 $-0.04 $-0.07 0.03%
30 Juni 2025 $0.01 $-0.08 0.09%
31 Maret 2025 $-0.07 $-0.10 0.03%

Perbandingan rekan (sub-industri GICS) Metrik utama vs rekan sektor

Ticker Kapitalisasi Pasar P/E Pendapatan YoY Margin Bersih ROE Margin Kotor
LXRX $421M -8.2 60.2% -101.1% -39.7%
ANRO $568M -8.1 -46.1%
EYPT $1.51B -5.8 -27.5% -739.4% -84.0%
OMER $1.23B -343.6 1.9%
PCRX $1.06B 161.8 3.6% 0.97% 0.97%
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
AMPH $1.22B 13.2 -1.7% 13.6% 12.7% 49.5%
ACRS $363M -5.7 -58.2% -829.6% -55.3%
SGP 50.0%
LLY 46.8 44.7% 31.7% 101.2%

Fundamental Lengkap Semua metrik per tahun — laporan laba rugi, neraca, arus kas

Laporan Laba Rugi 16
Data Laporan Laba Rugi Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +117.9% $50M $31M $1M $139.0K $298.0K $24M $322M $63M $92M $79M $130M $23M
Cost of Revenue 11-point trend, +274000.00 $274.0K $616.0K $85.0K $0 $0 $2M $3M $2M $2M $0 $0 ·
R&D Expense 12-point trend, -31.5% $61M $84M $59M $53M $55M $154M $92M $100M $152M $164M $95M $89M
SG&A Expense 12-point trend, +92.3% $37M $143M $114M $48M $32M $47M $57M $64M $66M $43M $24M $19M
Operating Expenses 12-point trend, -19.9% $99M $228M $173M $101M $87M $204M $181M $166M $222M $206M $129M $123M
Operating Income 12-point trend, +51.3% $-49M $-197M $-172M $-101M $-87M $-48M $141M $-103M $-131M $-127M $1M $-100M
Interest Expense 9-point trend, +23.4% · · · $3M $802.0K $15M $21M $21M $7M $7M $7M $2M
Other Non-op 12-point trend, +206.4% $7M $12M $8M $2M $134.0K $3M $3M $4M $2M $2M $572.0K $2M
Pretax Income 8-point trend, +12.6% · · · · $-88M $-59M $124M $-121M $-136M $-131M $-5M $-100M
Income Tax 7-point trend, +100.0% · $0 $0 $0 $0 · · · · $0 $0 $-70.0K
Net Income 12-point trend, +49.8% $-50M $-200M $-177M $-102M $-88M $-59M $130M $-121M $-123M $-131M $-5M $-100M
EPS (Basic) 9-point trend, +88.0% $-0.14 $-0.63 $-0.80 $-0.62 $-0.60 $-0.53 $1.23 $-1.14 $-1.17 · · ·
EPS (Diluted) 9-point trend, +88.0% $-0.14 $-0.63 $-0.80 $-0.62 $-0.60 $-0.53 $1.16 $-1.14 $-1.17 · · ·
Shares (Basic) 5-point trend, +149.3% 363,053,000 320,031,000 221,130,000 165,733,000 145,652,000 · · · · · · ·
Shares (Diluted) 9-point trend, +245.0% 363,053,000 320,031,000 221,130,000 165,733,000 145,652,000 110,841,000 116,747,000 105,830,000 105,237,000 · · ·
EBITDA 11-point trend, +50.9% $-48M $-197M $-171M $-100M $-87M $-45M $145M $-100M $-133M $-135M · $-98M
Neraca 30
Data Neraca Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, -75.0% $34M $67M $22M $46M $64M $126M $36M $80M $62M $47M $203M $137M
Short-term Investments 12-point trend, -69.4% $62M $171M $148M $92M $23M $26M $236M $80M $249M $300M $318M $202M
Receivables 12-point trend, +130.3% $2M $3M $1M $28.0K $14.0K $395.0K $57M $6M $5M $7M $911.0K $1M
Inventory 9-point trend, +281000.00 $281.0K $231.0K $381.0K $0 · $0 $4M $5M $2M $0 · ·
Other Current Assets 12-point trend, -37.0% $3M $5M $5M $2M $2M $5M $5M $3M $4M $4M $10M $5M
Current Assets 12-point trend, -72.4% $102M $246M $177M $141M $89M $158M $338M $173M $322M $358M $532M $369M
PP&E (Net) 12-point trend, +72.5% $2M $2M $2M $2M $1M $295.0K $14M $16M $18M $19M $21M $1M
PP&E (Gross) 12-point trend, -87.8% $5M $5M $7M $6M $6M $6M $76M $76M $76M $79M $81M $37M
Accum. Depreciation 12-point trend, -92.5% $3M $2M $5M $4M $5M $6M $62M $60M $59M $60M $59M $36M
Goodwill Flat — no change across 12 periods $45M $45M $45M $45M $45M $45M $45M $45M $45M $45M $45M $45M
Intangibles 6-point trend, -63.0% · · · · · · $20M $50M $52M $53M $53M $53M
Other Non-current Assets 12-point trend, -89.2% $368.0K $368.0K $828.0K $412.0K $2M $1M $2M $285.0K $429.0K $461.0K $433.0K $3M
Total Assets 12-point trend, -60.8% $185M $298M $229M $194M $137M $204M $418M $284M $437M $476M $652M $471M
Accounts Payable 12-point trend, -76.4% $3M $15M $14M $10M $9M $5M $12M $12M $39M $53M $20M $13M
Accrued Liabilities 12-point trend, +30.3% $13M $30M $17M $13M $13M $30M $42M $21M $12M $32M $25M $10M
Current Liabilities 12-point trend, -53.6% $21M $45M $32M $23M $22M $47M $65M $37M $105M $165M $123M $45M
Capital Leases 4-point trend, +21.7% $7M $5M $5M $5M · · · · · · · ·
Deferred Tax 6-point trend, -100.0% · · · · · · $0 $6M $6M $19M $19M $19M
Other Non-current Liabilities 12-point trend, -69.5% $7M $7M $5M $5M $1M $611.0K $1M $238.0K $292.0K $805.0K $14M $24M
Total Liabilities 12-point trend, -58.7% $77M $152M $136M $77M $23M $47M $301M $311M $368M $318M $366M $187M
Long-term Debt 11-point trend, -49.8% $54M $100M · $49M $0 $12M $249M $250M $252M $101M $106M $108M
Total Debt 10-point trend, -49.8% $54M $100M $100M · $0 $12M $245M $245M $246M $101M · $108M
Common Stock 12-point trend, +251.9% $366.0K $363.0K $245.0K $189.0K $150.0K $142.0K $106.0K $106.0K $106.0K $105.0K $104.0K $104.0K
Paid-in Capital 12-point trend, +53.2% $2.13B $2.12B $1.86B $1.71B $1.61B $1.56B $1.46B $1.45B $1.44B $1.41B $1.40B $1.39B
Retained Earnings 12-point trend, -82.7% $-2.02B $-1.97B $-1.77B $-1.59B $-1.49B $-1.40B $-1.34B $-1.47B $-1.37B $-1.25B $-1.11B $-1.10B
Treasury Stock 12-point trend, +117.0% $5M $5M $3M $2M $8M $5M $4M $3M $2M $3M $3M $2M
AOCI 12-point trend, +147.6% $30.0K $119.0K $31.0K $-428.0K $-10.0K $-6.0K $84.0K $-12.0K $-222.0K $-195.0K $-219.0K $-63.0K
Stockholders' Equity 12-point trend, -62.1% $108M $146M $93M $117M $114M $156M $117M $-26M $68M $168M $286M $284M
Liabilities + Equity 12-point trend, -60.8% $185M $298M $229M $194M $137M $204M $418M $284M $437M $476M $652M $471M
Shares Outstanding 11-point trend, +252.9% 365,848,216 363,020,303 · 189,214,000 150,082,000 142,289,000 106,679,000 106,162,000 105,711,000 104,582,000 103,860,000 103,663,000
Arus Kas 17
Data Arus Kas Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
D&A 12-point trend, -67.8% $621.0K $534.0K $554.0K $427.0K $292.0K $3M $4M $4M $3M $2M $727.0K $2M
Stock-based Comp 12-point trend, +76.8% $13M $13M $14M $12M $11M $13M $14M $12M $9M $7M $7M $7M
Deferred Tax 9-point trend, +100.0% · · · $0 $0 $0 $-6M $0 $-13M $0 $0 $-70.0K
Amort. of Intangibles 2-point trend, +20.0% · · · · · · · $2M $2M · · ·
Other Non-cash 11-point trend, -296.5% $-31M $8M $328.0K $1M $-10M $-101M $-28M $-43M $-57M $-44M · $16M
Operating Cash Flow 12-point trend, +10.3% $-68M $-179M $-162M $-89M $-87M $-143M $114M $-149M $-185M $-176M $185M $-76M
CapEx 12-point trend, -100.0% $0 $1M $470.0K $1M $1M $87.0K $70.0K $95.0K $228.0K $231.0K $910.0K $80.0K
Investing Cash Flow 12-point trend, +204.2% $113M $-15M $-50M $-71M $2M $381M $-156M $170M $51M $18M $-117M $-108M
Debt Issued 11-point trend, -100.0% $0 $0 $50M $49M · $0 $0 $13M $146M $0 $0 $84M
Net Debt Issued 10-point trend, -100.0% $0 $0 · $49M $-12M $-217M $-1M $-2M $144M $-2M · $82M
Stock Issued 12-point trend, -100.0% $0 $0 $139M $94M $37M $70M $0 $732.0K $8M $4M $114.0K $202M
Stock Repurchased 11-point trend, +95.0% · $2M $824.0K $864.0K $3M $1M $941.0K $972.0K $2M $621.0K $357.0K $887.0K
Net Stock Activity 11-point trend, -100.0% $0 $-2M $138M $93M $34M $69M $-941.0K $-240.0K $6M $3M · $201M
Financing Cash Flow 12-point trend, -117.1% $-48M $238M $188M $142M $23M $-148M $-2M $-2M $150M $987.0K $-2M $284M
Net Change in Cash 12-point trend, -103.3% $-3M $44M $-24M $-18M $-62M $90M $-44M $19M $15M $-156M $66M $100M
Free Cash Flow 11-point trend, +10.4% $-68M $-180M $-162M $-90M $-88M $-143M $114M $-149M $-186M $-176M · $-76M
Levered FCF 2-point trend, -134.0% · · · · · · · · · $-182M · $-78M
Profitabilitas 7
Data Profitabilitas Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +77.6% -98.2% -634.2% -14264.9% -72489.2% -29224.8% -199.2% 43.9% -163.4% -151.3% -164.6% · -439.2%
Net Margin 11-point trend, +77.0% -101.1% -644.8% -14710.9% -73341.0% -29449.0% -244.1% 40.4% -190.7% -142.9% -169.7% · -438.8%
Pretax Margin 7-point trend, -6605.9% · · · · -29449.0% -244.1% 38.5% -190.7% -156.9% -169.7% · -439.1%
EBITDA Margin 11-point trend, +77.5% -97.0% -632.5% -14218.9% -72182.0% -29126.9% -187.0% 45.1% -157.6% -147.5% -162.1% · -430.7%
ROA 11-point trend, +22.6% -20.8% -75.9% -83.6% -61.6% -51.5% -18.9% 37.1% -33.5% -28.3% -25.1% · -26.9%
ROE 11-point trend, +10.1% -39.7% -167.7% -168.5% -88.4% -65.0% -42.8% 287.0% -576.0% -117.5% -63.8% · -44.2%
ROIC 2-point trend, -106.9% · · · · · · · · · -53.0% · -25.6%
Likuiditas & Solvabilitas 5
Data Likuiditas & Solvabilitas Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -40.5% 4.9 5.4 5.6 6.1 4.0 3.4 5.2 4.7 2.6 2.2 · 8.2
Quick Ratio 11-point trend, -37.6% 4.7 5.3 5.4 6.0 3.9 3.3 5.0 4.5 2.5 2.2 · 7.6
Debt / Equity 10-point trend, +32.5% 0.5 0.7 1.1 · 0.0 0.1 2.1 -9.3 4.7 0.6 · 0.4
LT Debt / Equity 9-point trend, +49.1% 0.5 0.7 1.1 · · 0.0 2.0 -9.2 4.4 0.5 · 0.3
Interest Coverage 8-point trend, +18.6% · · · -36.2 -108.6 -3.3 6.8 -5.0 -19.6 -20.9 · -44.5
Efisiensi 3
Data Efisiensi Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, +236.1% 0.2 0.1 0.0 0.0 0.0 0.1 0.9 0.2 0.2 0.1 · 0.1
Inventory Turnover 7-point trend, -45.1% 1.1 2.0 0.4 · · 0.9 0.7 0.8 1.9 · · ·
Receivables Turnover 11-point trend, -32.1% 17.0 13.9 2.3 6.6 1.5 0.8 10.3 11.8 14.7 19.8 · 25.0
Per Saham 5
Data Per Saham Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
Book Value / Share 9-point trend, -24.9% $0.29 · · $0.62 $0.76 $1.10 $1.10 $-0.25 $0.49 $1.50 · $0.39
Revenue / Share 6-point trend, -95.0% $0.14 $0.10 $0.01 · $0.00 $0.22 $2.76 · · · · ·
Cash Flow / Share 6-point trend, -119.2% $-0.19 $-0.56 $-0.73 · $-0.60 $-1.29 $0.97 · · · · ·
Cash / Share 9-point trend, -50.4% $0.09 · · $0.24 $0.43 $0.89 $0.34 $0.76 $0.58 $0.45 · $0.19
EPS (TTM) 11-point trend, -16.7% $-0.14 $-0.63 $-0.80 $-0.62 $-0.60 $-0.53 $1.16 $-1.14 $-1.17 $-0.12 $-0.12 ·
Tingkat Pertumbuhan 3
Data Tingkat Pertumbuhan Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +161.0% 60.2% 2481.5% 766.2% -53.4% -98.8% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +1066.8% 610.2% 370.7% -63.1% · · · · · · · · ·
Revenue CAGR 5Y 15.7% · · · · · · · · · · ·
Valuasi (TTM) 14
Data Valuasi (TTM) Tahunan untuk LXRX
Metrik Tren 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +117.9% $50M $31M $1M $139.0K $298.0K $24M $322M $63M $92M $79M $130M $23M
Net Income TTM 12-point trend, +49.8% $-50M $-200M $-177M $-102M $-88M $-59M $130M $-121M $-123M $-131M $-5M $-100M
Market Cap 9-point trend, -90.9% $421M · · $361M $591M $487M $443M $705M $1.04B $1.45B · $4.62B
Enterprise Value 8-point trend, -91.4% $378M · · · $505M $346M $416M $790M $979M $1.20B · $4.39B
P/E 11-point trend, +92.6% -8.2 -1.2 -1.9 -3.1 -6.6 -6.5 3.6 -5.8 -8.4 -115.2 -110.9 ·
P/S 9-point trend, -95.8% 8.4 · · 2600.0 1984.3 20.3 1.4 11.2 11.4 18.2 · 202.3
P/B 9-point trend, -76.0% 3.9 · · 3.1 5.2 3.1 3.8 -26.7 20.0 9.2 · 16.3
P / Tangible Book 4-point trend, +53.5% 6.7 · · 5.0 8.6 4.4 · · · · · ·
P / Cash Flow 9-point trend, +89.9% -6.2 · · -4.1 -6.8 -3.4 3.9 -4.7 -5.6 -8.2 · -61.1
P / FCF 9-point trend, +89.8% -6.2 · · -4.0 -6.7 -3.4 3.9 -4.7 -5.6 -8.2 · -61.1
EV / EBITDA 8-point trend, +82.4% -7.8 · · · -5.8 -7.7 2.9 -7.9 -7.3 -8.9 · -44.6
EV / FCF 8-point trend, +90.4% -5.6 · · · -5.7 -2.4 3.7 -5.3 -5.3 -6.8 · -58.0
EV / Revenue 8-point trend, -96.0% 7.6 · · · 1693.2 14.4 1.3 12.5 10.7 15.2 · 192.1
Earnings Yield 11-point trend, -1252.2% -12.2% -85.1% -52.3% -32.5% -15.2% -15.5% 28.0% -17.2% -11.8% -0.87% -0.90% ·

Laporan Keuangan Laporan laba rugi, neraca, arus kas — tahunan, 5 tahun terakhir

Laporan Laba Rugi
2025-12-312024-12-312023-12-312022-12-312021-12-31
Pendapatan $50M$31M$1M$139.0K$298.0K
Margin Operasi % -98.2%-634.2%-14264.9%-72489.2%-29224.8%
Laba Bersih $-50M$-200M$-177M$-102M$-88M
EPS Dilusian $-0.14$-0.63$-0.80$-0.62$-0.60
Neraca
2025-12-312024-12-312023-12-312022-12-312021-12-31
Utang / Ekuitas 0.50.71.10.0
Rasio Lancar 4.95.45.66.14.0
Rasio Cepat 4.75.35.46.03.9
Arus Kas
2025-12-312024-12-312023-12-312022-12-312021-12-31
Arus Kas Bebas $-68M$-180M$-162M$-90M$-88M

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Pemilik institusional (13F) 169 pengaju · $760.9M total · Per tanggal 30 Juni 2026

Institusi yang melaporkan kepemilikan saham ini dalam SEC Form 13F triwulanan mereka. Hanya posisi panjang; satu pengaju dapat muncul dua kali untuk leg opsi terpisah. Kaki put/call offset yang besar biasanya mencerminkan pembuatan pasar atau inventaris yang dilindungi, bukan keyakinan arah.

Aktivitas institusional — Q2 2026 vs kuartal sebelumnya
Posisi baru Posisi yang keluar Meningkat Menurun Perubahan bersih saham
48 (+19 vs Kuartal sebelumnya) 26 (+13 vs Kuartal sebelumnya) 34 (-11 vs Kuartal sebelumnya) 37 (+17 vs Kuartal sebelumnya) +36.5M

Dibandingkan dengan Q1 2026. Pengajuan Formulir 13F SEC jatuh tempo dalam waktu 45 hari setelah akhir kuartal ditambah kelonggaran singkat untuk pengaju terlambat — kuartal yang masih dalam jangka waktu tersebut dilewati demi pasangan terakhir yang dilaporkan sepenuhnya.

Institusi Nilai Saham % dari 13F yang dilacak Tipe
Artal Group S.A. $420.374.549 175.156.062 55,25% Saham
Siren, L.L.C. $106.328.443 44.303.518 13,97% Saham
FMR LLC $65.057.059 27.107.108 8,55% Saham
Sessa Capital IM, L.P. $45.506.006 18.960.836 5,98% Saham
VANGUARD CAPITAL MANAGEMENT LLC $23.762.899 9.901.208 3,12% Saham
Point72 Asset Management, L.P. $19.803.180 8.251.325 2,60% Saham
GEODE CAPITAL MANAGEMENT, LLC $12.946.507 5.393.025 1,70% Saham
STATE STREET CORP $11.802.646 4.917.769 1,55% Saham
VANGUARD PORTFOLIO MANAGEMENT LLC $5.658.598 2.357.749 0,74% Saham
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4.696.260 1.956.775 0,62% Saham
VANGUARD FIDUCIARY TRUST CO $3.922.970 1.634.571 0,52% Saham
CIBC Private Wealth Group LLC $3.240.347 2.400.257 0,43% Saham
Ishara Investments LP $3.050.400 1.271.000 0,40% Saham
MILLENNIUM MANAGEMENT LLC $2.722.150 1.134.229 0,36% Saham
RENAISSANCE TECHNOLOGIES LLC $2.704.800 1.127.000 0,36% Saham
MACKENZIE FINANCIAL CORP $2.312.050 963.354 0,30% Saham
ADAR1 Capital Management, LLC $1.800.000 750.000 0,24% Saham
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1.604.400 668.500 0,21% Opsi beli
TWO SIGMA INVESTMENTS, LP $1.544.266 643.444 0,20% Saham
JANE STREET GROUP, LLC $1.398.960 582.900 0,18% Opsi beli
CITADEL ADVISORS LLC $1.348.733 561.972 0,18% Saham
VANGUARD GROUP INC $1.277.587 1.110.945 0,17% Saham
Compagnie Lombard Odier SCmA $1.152.000 480.000 0,15% Saham
BARCLAYS PLC $890.636 371.098 0,12% Saham
CITADEL ADVISORS LLC $886.320 369.300 0,12% Opsi beli
XTX Topco Ltd $858.905 357.877 0,11% Saham
GOLDMAN SACHS GROUP INC $725.810 302.421 0,10% Saham
CANADA PENSION PLAN INVESTMENT BOARD $618.960 257.900 0,08% Saham
RHUMBLINE ADVISERS $616.523 256.885 0,08% Saham
WELLS FARGO & COMPANY/MN $544.865 227.027 0,07% Saham
GROUP ONE TRADING LLC $420.031 175.013 0,06% Saham
Virtus Investment Advisers, LLC $408.996 170.415 0,05% Saham
Headlands Technologies LLC $401.275 167.198 0,05% Saham
Ikarian Capital, LLC $395.218 164.674 0,05% Saham
CITIGROUP INC $386.021 160.842 0,05% Saham
Quarry LP $374.846 156.186 0,05% Saham
MetLife Investment Management, LLC $351.384 146.410 0,05% Saham
Bank of New York Mellon Corp $345.307 143.878 0,05% Saham
BANK OF AMERICA CORP /DE/ $344.321 143.467 0,05% Saham
PANAGORA ASSET MANAGEMENT INC $316.901 132.042 0,04% Saham
State of Wyoming $285.816 119.090 0,04% Saham
BlackRock, Inc. $284.436 118.515 0,04% Saham
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $273.874 114.114 0,04% Saham
Cornerstone Investment Partners, LLC $272.974 113.739 0,04% Saham
Invesco Ltd. $238.190 99.246 0,03% Saham
ALGERT GLOBAL LLC $221.160 92.150 0,03% Saham
TWO SIGMA ADVISERS, LP $208.124 180.977 0,03% Saham
BANK OF NOVA SCOTIA $207.857 86.607 0,03% Saham
LPL Financial LLC $203.799 84.916 0,03% Saham
Vanguard Global Advisers, LLC $187.070 77.946 0,02% Saham
AQR CAPITAL MANAGEMENT LLC $180.101 75.042 0,02% Saham
Police & Firemen's Retirement System of New Jersey $176.165 73.402 0,02% Saham
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT CO $171.426 71.427 0,02% Saham
PRUDENTIAL FINANCIAL INC $171.228 71.345 0,02% Saham
MANUFACTURERS LIFE INSURANCE COMPANY, THE $167.393 69.747 0,02% Saham
NEW YORK STATE COMMON RETIREMENT FUND $164.160 68.400 0,02% Saham
TWO SIGMA SECURITIES, LLC $159.300 66.375 0,02% Saham
SEI INVESTMENTS CO $153.449 63.937 0,02% Saham
Nuveen, LLC $153.449 63.937 0,02% Saham
Straight Path Wealth Management $150.398 62.666 0,02% Saham
WELLINGTON MANAGEMENT GROUP LLP $144.000 60.000 0,02% Saham
R Squared Ltd $131.964 54.985 0,02% Saham
Vanguard Personalized Indexing Management, LLC $130.402 54.334 0,02% Saham
Fortis Group Advisors, LLC $120.000 50.000 0,02% Saham
Schonfeld Strategic Advisors LLC $118.642 49.435 0,02% Saham
SCOTIA CAPITAL INC. $117.291 48.871 0,02% Saham
PROFUND ADVISORS LLC $116.606 48.586 0,02% Saham
VOYA INVESTMENT MANAGEMENT LLC $114.650 47.771 0,02% Saham
AXQ CAPITAL, LP $109.745 45.727 0,01% Saham
BOOTHBAY FUND MANAGEMENT, LLC $106.356 44.315 0,01% Saham
ALLIANCEBERNSTEIN L.P. $105.768 67.800 0,01% Saham
WINTON GROUP Ltd $103.680 43.200 0,01% Saham
INTECH INVESTMENT MANAGEMENT LLC $101.978 42.491 0,01% Saham
LMR Partners LLP $98.618 41.091 0,01% Saham
BANK OF MONTREAL /CAN/ $96.000 40.000 0,01% Saham
NORTHERN TRUST CORP $93.794 39.081 0,01% Saham
BNP PARIBAS FINANCIAL MARKETS $90.672 37.780 0,01% Saham
Cubist Systematic Strategies, LLC $85.704 63.484 0,01% Saham
Rafferty Asset Management, LLC $81.816 34.090 0,01% Saham
ProShare Advisors LLC $78.212 32.588 0,01% Saham
Leonteq Securities AG $72.000 30.000 0,01% Saham
PINNACLE ASSOCIATES LTD $69.636 29.015 0,01% Saham
VICTORY CAPITAL MANAGEMENT INC $58.135 24.223 0,01% Saham
Legal & General Group Plc $58.044 24.185 0,01% Saham
XPONANCE LLC $57.031 23.763 0,01% Saham
Graham Capital Management, L.P. $56.498 23.541 0,01% Saham
D. E. Shaw & Co., Inc. $53.280 22.200 0,01% Saham
Quadrature Capital Ltd $52.795 21.998 0,01% Saham
Invera Wealth Advisors, LLC $48.000 20.000 0,01% Saham
DIKER MANAGEMENT LLC $48.000 20.000 0,01% Saham
TIAA-CREF INDIVIDUAL & INSTITUTIONAL SERVICES, LLC $48.000 20.000 0,01% Saham
Russell Investments Group, Ltd. $47.764 19.902 0,01% Saham
Point72 Asia (Singapore) Pte. Ltd. $47.282 35.024 0,01% Saham
Tower Research Capital LLC (TRC) $46.764 19.485 0,01% Saham
KWB Wealth $46.736 40.640 0,01% Saham
SBI Securities Co., Ltd. $46.092 19.205 0,01% Saham
PRINCIPAL FINANCIAL GROUP INC $45.682 19.034 0,01% Saham
CREDIT AGRICOLE S A $45.540 18.975 0,01% Saham
WOLVERINE TRADING, LLC $43.785 31.500 0,01% Opsi jual
SUSQUEHANNA INTERNATIONAL GROUP, LLP $42.960 17.900 0,01% Opsi jual

Orang dalam perusahaan 49 orang dalam · 32 pejabat · 19 direktur

Orang Dalam Peran Aktivitas terakhir Saham dimiliki Beli 12m Jual 12m Bersih 12m
Michael Exton Chief Executive Officer 28 Feb. 2026 M 298.432 0 0 $0
Lonnel Coats Chief Executive Officer 28 Feb. 2024 M 1.098.068 0 0 $0
Arthur T Sands President & CEO 28 Feb. 2014 M 1.021.329 0 0 $0
Scott M Coiante SVP, Chief Financial Officer 28 Feb. 2026 M 105.356 0 0 $0
Ajay Bansal EVP Corp Dev and CFO 2 Juni 2009 A 0 0 $0
Julia P Gregory EVP and CFO 7 Feb. 2008 A 50.200 0 0 $0
Jeffrey L Wade President and COO 8 Juli 2024 A 324.214 0 0 $0
Rachel Yap Martens SVP, Partnerships & Corp Strat 28 Feb. 2026 M 31.264 0 0 $0
Suma Gopinathan SVP, Discovery 28 Feb. 2026 M 150.132 0 0 $0
Wendy Mcdermott SVP, Human Resources 28 Feb. 2026 M 277.945 0 0 $0
Craig B Granowitz SVP, Chief Medical Officer 28 Feb. 2026 M 323.430 0 0 $0
Lisa Defrancesco SVP, IR and Corp Comm 28 Feb. 2026 M 93.869 0 0 $0
Brian T Crum SVP, General Counsel & Secr. 28 Feb. 2026 M 428.802 0 0 $0
Kristen Alexander VP, Finance and Accounting 28 Feb. 2025 M 76.368 0 0 $0
Alan J Main EVP, Innov & Chem Sciences 28 Feb. 2025 M 339.104 0 0 $0
Brian Corrigan SVP, Regulatory & QA 13 Feb. 2025 A 0 0 $0
Kenneth B. Kassler-Taub SVP, Regulatory & QA 28 Feb. 2024 M 162.672 0 0 $0
Thomas Garner SVP, Chief Commercial Officer 8 Feb. 2024 A 0 0 $0
Kiernan Seth VP, Chief Commercial Officer 28 Feb. 2023 M 53.136 0 0 $0
James F Tessmer VP, Finance & Accounting 15 Maret 2021 M 71.766 0 0 $0
Alexander A Santini EVP and CCO 22 April 2020 F 55.584 0 0 $0
Pablo Lapuerta EVP and CMO 22 April 2020 F 85.719 0 0 $0
John Northcott VP, Marketing, Comm Strategy 2 Maret 2015 M 8.235 0 0 $0
Brian P Zambrowicz EVP, Chief Scientific Officer 28 Feb. 2014 M 278.703 0 0 $0
Steven Alan Tragash VP, Corporate Affairs 15 Feb. 2010 A 0 0 $0
Philip M Brown SVP, Clinical Development 15 Feb. 2010 A 27.306 0 0 $0
James R Piggott PHD SVP of Pharm Bio 7 Feb. 2008 A 0 0 0 $0
Lance K Ishimoto SVP, Intellectual Property 7 Feb. 2008 A 10.200 0 0 $0
Tamar D Howson EVP of Bus Dev 7 Feb. 2008 A 0 0 $0
Walter F Colbert SVP, HR and Corp Serv 13 Feb. 2007 A 0 0 $0
Randall B Riggs SVP, Corp Licensing 23 Feb. 2004 M 15.000 0 0 $0
Christophe Person VP Informatics 12 Jan. 2004 M 0 0 0 $0
Ivan Cheung Direktur 3 Juni 2026 M 89.312 0 0 $0
Diane E. Sullivan Direktur 3 Juni 2026 M 126.122 0 0 $0
Judith L Swain Direktur 3 Juni 2026 M 174.486 0 0 $0
Amouyal Philippe Direktur 3 Juni 2026 M 374.486 0 0 $0
Sam L Barker Direktur 3 Juni 2026 M 213.771 0 0 $0
Christopher J Sobecki Direktur 3 Juni 2026 M 293.177 0 0 $0
Raymond Debbane Direktur 3 Juni 2026 M 1.995.498 7 0 $723.048
Robert J Lefkowitz MD Direktur 13 Mei 2024 A 48.364 0 0 $0
Frank Palantoni Direktur 21 Mei 2023 M 40.332 0 0 $0
Alan S Nies Direktur 21 Mei 2023 M 41.046 0 0 $0
Invus C.V. Direktur 31 Des. 2020 J 0 0 0 $0
Kathleen M Wiltsey Direktur 24 April 2009 A 0 0 $0
Clayton Stuart Rose Direktur 26 Juni 2007 P 25.000 0 0 $0
Barry Mills Direktur 26 April 2007 A 25.000 0 0 $0
Patricia M Cloherty Direktur 27 April 2006 A 0 0 $0
Thomas C Caskey Direktur 13 Okt. 2005 P 6.300 0 0 $0
Praveen Tyle 28 Feb. 2021 M 120.791 0 0 $0

Orang dalam dari pengajuan SEC Form 3/4/5; bersih = hanya P/S pasar terbuka

Aktivis & pemilik 5%+ 11 saham

Investor yang mengajukan Jadwal 13D SEC — kepemilikan manfaat di atas 5% dengan niat untuk memengaruhi penerbit (kepemilikan aktivis, kampanye dewan, M&A). Setiap baris menunjukkan status terbaru yang diketahui dari posisi pengaju tersebut.

Pengaju Diajukan Kepemilikan Status Tujuan Pengajuan
Invus, L.P., Invus Advisors, L.L.C., Invus Public Equities, L.P., Invus Public Equities Advisors, LLC, Invus Global Management, LLC, Siren, L.L.C., Avicenna Life Sci Master Fund LP, Avicenna Life Sci Master GP LLC, Invus US Partners LLC, Ulys, L.L.C., Raymond Debbane, Artal Participations S.a r.l., Artal International S.C.A., Artal International Management S.A., Artal Group S.A., Westend S.A., Stichting Administratiekantoor Westend, Amaury Wittouck ×7 pengajuan 8 Mei 2026 39,40% Amandemen SEC
Invus, L.P. (2), Invus Advisors, L.L.C. (2), Invus Public Equities, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Global Management, LLC (2), Siren, L.L.C. (2), Artal Participations S.à r.l. (2), Artal International S.C.A. (2), Artal International Management S.A. (2), Artal Group S.A. (2), Westend S.A. (2), Stichting Administratiekantoor Westend (2), Mr. Amaury Wittouck (2), Invus US Partners LLC (2), Ulys, L.L.C. (2), Mr. Raymond Debbane (2) ×15 pengajuan 9 Des. 2024 Pengajuan awal SEC
24 Feb. 2012 Pengajuan awal SEC
Raymond Debbane (2), Ulys, L.L.C. (2), Invus Advisors, L.L.C. (2), Invus, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Public Equities, L.P. (2), Invus C.V. (2) 27 Des. 2011 Pengajuan awal SEC
14 Nov. 2011 Pengajuan awal SEC
15 Agu 2011 Pengajuan awal SEC
Raymond Debbane, Ulys, L.L.C., Invus Advisors, L.L.C., Invus, L.P., Invus Public Equities Advisors, LLC, Invus Public Equities, L.P., Invus C.V. 19 Maret 2010 Pengajuan awal SEC
Estate of Gordon A. Cain (, Mary H. Cain ×4 pengajuan 5 Agu 2005 Pengajuan awal SEC
Orang pelapor yang tidak diungkapkan, Orang pelapor yang tidak diungkapkan, Orang pelapor yang tidak diungkapkan 8 Agu 2003 Pengajuan awal SEC
Orang pelapor yang tidak diungkapkan, Orang pelapor yang tidak diungkapkan, Orang pelapor yang tidak diungkapkan 18 Juli 2003 Pengajuan awal Investasi pasif SEC
Orang pelapor yang tidak diungkapkan, Orang pelapor yang tidak diungkapkan, Orang pelapor yang tidak diungkapkan, Orang pelapor yang tidak diungkapkan 19 Maret 2003 Pengajuan awal SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Kepemilikan ETF Dimiliki oleh 14 ETF

Bobot mencerminkan kepemilikan ekuitas langsung (N-PORT) saja; dana berbasis leverage atau derivatif mungkin memiliki eksposur swap tambahan yang tidak ditampilkan.

Dana Bobot Unit Per tanggal Sumber
QQQS · Invesco Exchange-Traded Fund Trust … 0,56% 51.356 SH 8 Agu 2026 Harian
IWC · iShares Trust 0,13% 841.693 SH 8 Agu 2026 Harian
VTWG · VANGUARD SCOTTSDALE FUNDS 0,04% 266.401 SH 8 Agu 2026 Harian
IWO · iShares Trust 0,04% 2.223.001 SH 8 Agu 2026 Harian
PRFZ · Invesco Exchange-Traded Fund Trust 0,03% 323.271 SH 8 Agu 2026 Harian
VTWO · VANGUARD SCOTTSDALE FUNDS 0,02% 1.432.882 SH 8 Agu 2026 Harian
IWM · iShares Trust 0,02% 6.194.737 SH 8 Agu 2026 Harian
VXF · VANGUARD INDEX FUNDS 0,01% 2.594.934 SH 8 Agu 2026 Harian
VHT · VANGUARD WORLD FUND 0,01% 637.561 SH 8 Agu 2026 Harian
SCHA · SCHWAB STRATEGIC TRUST 0,01% 1.032.223 NS 31 Mei 2026 N-PORT
IWV · iShares Trust 0,00% 84.479 SH 8 Agu 2026 Harian
SCHB · SCHWAB STRATEGIC TRUST 0,00% 110.085 NS 31 Mei 2026 N-PORT
VTI · VANGUARD INDEX FUNDS 0,00% 7.083.651 SH 8 Agu 2026 Harian
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 20.905 SH 8 Agu 2026 Harian