PTCT PTC Therapeutics, Inc. - Common Stock

NASDAQ · Biotechnology · Lihat di SEC EDGAR ↗
$72,62
Harga · Agu 19, 2026
Fundamental per Jul 30, 2026

Tentang PTC Therapeutics, Inc. - Common Stock Tinjauan perusahaan dari Wikipedia

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

Baca selengkapnya

PTC Therapeutics, Inc. is a US pharmaceutical company focused on the development of orally administered small molecule drugs and gene therapy which regulate gene expression by targeting post-transcriptional control (PTC) mechanisms in orphan diseases.

In September 2009, PTC entered into an agreement with Roche for the development of orally bioavailable small molecules for central nervous system diseases. PTC acquired the Bio-e platform in 2019.

Products

In 2017, PTC acquired Emflaza (deflazacort) from Marathon Pharmaceuticals. PTC also owns Translarna, (Ataluren) marketed for nonsense mutation Duchenne muscular dystrophy. Together, the two products generated revenues of 174 million dollars and 260 million dollars in 2017 and 2018 respectively.

PTC has the commercialization rights for WAYLIVRA (volanesorsen) in Latin America.

In 2018, PTC acquired Agilis Biotherapeutics and a gene therapy candidate, GT-AADC, with its compelling clinical data in treating aromatic L-amino acid decarboxylase (AADC) deficiency. AADC deficiency is a rare CNS disorder arising from reductions in the enzyme AADC that result from mutations in the dopa decarboxylase (DDC) gene. As of 2024, the AAV based treatment for AADC deficiency has been approved by the FDA and commercialized in the United States as Kebilidi. It is the first FDA-approved gene therapy treatment for AADC deficiency. This same product was granted EMA approval for use in the European Union under the name Upstaza.

Pipeline

In 2020, PTC acquired Censa Pharmaceuticals, Inc., a biopharmaceutical company focused on the development of CNSA-001 (sepiapterin), a clinical-stage investigational therapy for orphan metabolic diseases, including phenylketonuria (PKU) and other diseases associated with defects in the tetrahydrobiopterin (BH4) biochemical pathways diagnosed at birth.

In 2020, PTC announced the FDA approval of Evrysdi (risdiplam) for the treatment of spinal muscular atrophy (SMA) in adults and children 2 months and older.

In 2024, Novartis has committed $1 billion upfront in a licensing deal with PTC Therapeutics for an experimental treatment for Huntington’s disease, with the potential for an additional $1.9 billion tied to achieving specific development, regulatory, and commercial milestones. PTC Therapeutics’ therapy, known as PTC518, is an oral medication designed to reduce the production of the mutant protein linked to the genetic mutation responsible for the disease. This mutant protein is believed to contribute to neuronal death, driving disease progression. In June, interim data from a Phase 2 trial indicated that PTC518 successfully lowered levels of the mutant protein in both blood and cerebrospinal fluid.

Sumber: Wikipedia (English), CC BY-SA 4.0 · Lihat di Wikipedia ↗

Wikidata ↗

PTCT Cuplikan Saham Harga, kapitalisasi pasar, P/E, EPS, ROE, utang/ekuitas, kisaran 52 minggu

Harga
$72.62
Kapitalisasi Pasar
$5.92B
P/E (TTM)
9.3
EPS (TTM)
$7.78
Pendapatan (TTM)
$1.73B
Imbal Hasil Dividen
ROE
-331.5%
D/E Utang/Ekuitas
-1.4
Rentang 52M
$48 – $91

PTCT Grafik Harga Saham OHLCV harian dengan indikator teknis — geser, perbesar, dan sesuaikan tampilan Anda

Kinerja 10 Tahun Tren Pendapatan, laba bersih, margin, dan EPS

Pendapatan & Laba Bersih $1.73B
10-point trend, +1992.6%
2016-12-31 2025-12-31
EPS $7.78
7-point trend, +282.2%
2019-12-31 2025-12-31
Arus Kas Bebas $702M
9-point trend, +766.7%
2016-12-31 2025-12-31
Margin 39.4%

Valuasi Rasio P/E, P/S, P/B, EV/EBITDA — apakah sahamnya mahal atau murah?

Metrik
Tren 5 Tahun
PTCT
Median Rekan
P/E (TTM)
5-point trend, +282.1%
9.3
37.2
P/S (TTM)
5-point trend, -68.0%
3.4
9.9
P/B
5-point trend, -441.5%
-28.8
8.3
EV / EBITDA
5-point trend, +156.1%
4.7
Price / FCF (Harga / FCF)
5-point trend, +143.9%
8.4

Profitabilitas Margin kotor, operasional, dan bersih; ROE, ROA, ROIC

Metrik
Tren 5 Tahun
PTCT
Median Rekan
Operating Margin (Margin Operasi)
5-point trend, +144.2%
50.1%
Net Profit Margin (Margin Laba Bersih)
5-point trend, +134.3%
39.4%
-15.1%
ROA
5-point trend, +229.7%
29.7%
-23.3%
ROE
5-point trend, -275.6%
-331.5%
-30.6%
ROIC
5-point trend, +1860.3%
1044.7%

Kesehatan Keuangan Utang, likuiditas, solvabilitas — kekuatan neraca

Metrik
Tren 5 Tahun
PTCT
Median Rekan
Debt / Equity (Utang / Ekuitas)
5-point trend, -317.7%
-1.4
Current Ratio (Rasio Lancar)
5-point trend, -47.1%
2.3
6.3
Quick Ratio (Rasio Cepat)
5-point trend, -48.1%
2.2

Pertumbuhan Pertumbuhan Pendapatan, EPS, dan Laba Bersih: YoY, CAGR 3T, CAGR 5T

Metrik
Tren 5 Tahun
PTCT
Median Rekan
Revenue YoY (Pendapatan YoY)
5-point trend, +221.3%
114.5%
Revenue CAGR 3Y (CAGR Pendapatan 3T)
5-point trend, +221.3%
35.3%
Revenue CAGR 5Y (CAGR Pendapatan 5T)
5-point trend, +221.3%
35.4%

Metrik Per Saham EPS, nilai buku per saham, arus kas per saham, dividen per saham

Metrik
Tren 5 Tahun
PTCT
Median Rekan
EPS (Diluted)
5-point trend, +204.7%
$7.78

Efisiensi Modal Perputaran aset, perputaran persediaan, perputaran piutang

Metrik
Tren 5 Tahun
PTCT
Median Rekan

PTCT Konsensus Analis Opini analis bullish dan bearish, target harga 12 bulan, potensi kenaikan

BELI 21 analis
  • Beli Kuat 6 28,6%
  • Beli 11 52,4%
  • Tahan 3 14,3%
  • Jual 1 4,8%
  • Jual Kuat 0 0,0%

Target Harga 12 Bulan

14 analis · 2026-08-13
Target median $98.00 +34,9%
Target rata-rata $97.86 +34,8%

Riwayat Pendapatan EPS aktual vs perkiraan, kejutan %, tingkat keberhasilan, tanggal pendapatan berikutnya

Kejutan Rata-rata
1.9%
Periode EPS Aktual EPS Estimasi Kejutan
30 Juni 2026 $0.92 $0.43 0.49%
31 Maret 2026 $-0.03 $-0.48 0.45%
31 Des. 2025 $-1.67 $0.04 -1.7%
30 Sep. 2025 $0.20 $-1.40 1.6%
30 Juni 2025 $-0.83 $-1.08 0.25%
31 Maret 2025 $10.04 $-0.22 10.3%

Perbandingan rekan (sub-industri GICS) Metrik utama vs rekan sektor

Ticker Kapitalisasi Pasar P/E Pendapatan YoY Margin Bersih ROE Margin Kotor
PTCT $6.19B 9.8 114.5% 39.4% -331.5%
MIRM $4.10B -168.1 54.7% -4.5% -8.2%
COGT $5.72B -16.4 -83.1%
DNTH $1.78B -9.8 -67.3% -7973.3% -40.8%
ERAS $1.06B -8.5 -35.7%
CAI $7.62B -8.4 97.0% -8.4% -13.2%
TVTX $3.47B -131.8 110.5% -5.2% -34.6%
ACAD $4.55B 11.6 11.9% 36.5% 38.1%
DYN $3.23B -5.6 -57.8%
PBLS
CELC $4.81B -26.3 -244.3%

Fundamental Lengkap Semua metrik per tahun — laporan laba rugi, neraca, arus kas

Laporan Laba Rugi 15
Data Laporan Laba Rugi Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
Revenue 12-point trend, +6755.4% $1.73B $807M $938M $699M $539M $381M $307M $265M $194M $83M $37M $25M
Cost of Revenue 5-point trend, +12135000.00 · · · · · · $12M $13M $5M $0 $0 ·
R&D Expense 12-point trend, +470.2% $455M $534M $667M $651M $541M $478M $257M $172M $117M $118M $122M $80M
SG&A Expense 12-point trend, +674.5% $347M $301M $333M $326M $286M $245M $203M $154M $121M $97M $82M $45M
Operating Expenses 12-point trend, +592.9% $864M $1.11B $1.38B $1.15B $913M $813M $548M $380M $259M $215M $204M $125M
Operating Income 12-point trend, +972.1% $867M $-303M $-440M $-447M $-374M $-432M $-241M $-116M $-64M $-132M $-167M $-99M
Other Non-op 12-point trend, -8391.1% $-18M $7M $10M $-49M $-58M $85M $14M $129.0K $-1M $-1M $-465.0K $-213.0K
Pretax Income 12-point trend, +807.6% $697M $-363M $-696M $-587M $-518M $-403M $-240M $-128M $-78M $-142M $-170M $-98M
Income Tax 12-point trend, +397.8% $14M $176.0K $-70M $-28M $6M $35M $12M $-29.0K $1M $569.0K $485.0K $-5M
Net Income 12-point trend, +828.1% $683M $-363M $-627M $-559M $-524M $-438M $-252M $-128M $-79M $-142M $-170M $-94M
EPS (Basic) 10-point trend, +388.9% $8.58 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 $-2.75 $-2.02 · · $-2.97
EPS (Diluted) 8-point trend, +362.0% $7.78 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 · · · · $-2.97
Shares (Basic) 8-point trend, +152.0% 79,534,290 76,845,055 74,838,292 71,728,634 70,466,393 66,027,908 58,863,185 · · · · 31,565,310
Shares (Diluted) 8-point trend, +179.8% 88,311,494 76,845,055 74,838,292 71,728,634 70,466,393 66,027,908 58,863,185 · · · · 31,565,310
EBITDA 11-point trend, +1011.1% $906M $-227M $-203M · $-310M $-388M $-209M $-90M $-47M $-132M $-167M $-99M
Neraca 27
Data Neraca Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
Cash & Equivalents 12-point trend, +1879.3% $985M $780M $594M $280M $190M $209M $288M $169M $112M $58M $58M $50M
Short-term Investments 12-point trend, +261.9% $961M $360M $283M $131M $584M $895M $399M $58M $79M $173M $281M $265M
Receivables 12-point trend, +3986.0% $182M $159M $161M $156M $110M $70M $56M $68M $40M $25M $11M $4M
Inventory 10-point trend, +79647000.00 $80M $23M $31M $22M $16M $19M $19M $16M $11M $0 · ·
Prepaid Expense 12-point trend, +1632.5% $67M $44M $150M $106M $55M $39M $18M $9M $7M $5M $6M $4M
Current Assets 12-point trend, +602.8% $2.27B $1.37B $1.22B $694M $954M $1.23B $779M $321M $249M $261M $356M $324M
PP&E (Net) 12-point trend, +504.6% $55M $61M $87M $73M $53M $34M $22M $13M $8M $7M $9M $9M
PP&E (Gross) 12-point trend, +200.4% $102M $94M $138M $110M $80M $52M $33M $20M $41M $38M $37M $34M
Accum. Depreciation 12-point trend, +88.6% $47M $33M $51M $37M $27M $18M $12M $7M $33M $31M $28M $25M
Goodwill 9-point trend, +82341000.00 $82M $82M $82M $82M $82M $82M $82M $82M $0 · · ·
Intangibles 10-point trend, +388753000.00 $389M $119M $379M $706M $725M $715M $710M $701M $133M $0 · ·
Total Assets 12-point trend, +769.9% $2.90B $1.71B $1.90B $1.71B $1.94B $2.21B $1.62B $1.12B $392M $269M $365M $333M
Accounts Payable 12-point trend, +1001.9% $45M $17M $6M $27M $23M $19M $10M $6M $15M $6M $6M $4M
Current Liabilities 12-point trend, +2882.1% $968M $581M $603M $406M $509M $277M $236M $167M $82M $50M $45M $32M
Capital Leases 7-point trend, +937.7% $94M $75M $98M $101M $74M $79M $9M · · · · ·
Deferred Tax 7-point trend, +55905000.00 · · $56M $103M $137M $137M $131M $122M $0 · · ·
Other Non-current Liabilities 11-point trend, +501.8% $14M $21M $141.0K $3M · $1M $141.0K $58.0K $243.0K $335.0K $2M $2M
Total Liabilities 12-point trend, +8832.1% $3.10B $2.80B $2.71B $2.05B $1.94B $1.73B $1.03B $768M $235M $150M $139M $35M
Long-term Debt 4-point trend, +197.6% · · · · $431M · $314M $153M $145M · · ·
Total Debt 10-point trend, +203.0% $287M $285M $284M · $431M $309M $314M $153M $145M $98M $95M ·
Common Stock 12-point trend, +142.4% $80.0K $77.0K $75.0K $72.0K $71.0K $70.0K $62.0K $51.0K $42.0K $34.0K $34.0K $33.0K
Paid-in Capital 12-point trend, +280.8% $2.75B $2.57B $2.47B $2.31B $2.12B $2.17B $1.80B $1.29B $967M $856M $820M $722M
Retained Earnings 12-point trend, -601.5% $-2.96B $-3.65B $-3.28B $-2.66B $-2.10B $-1.63B $-1.19B $-939M $-814M $-735M $-593M $-423M
AOCI 12-point trend, +1524.8% $11M $-26M $-1M $5M $-24M $-61M $-11M $1M $4M $-1M $-1M $-737.0K
Stockholders' Equity 12-point trend, -168.8% $-205M $-1.10B $-819M $-347M $1M $482M $594M $351M $156M $120M $226M $298M
Liabilities + Equity 12-point trend, +769.9% $2.90B $1.71B $1.90B $1.71B $1.94B $2.21B $1.62B $1.12B $392M $269M $365M $333M
Shares Outstanding 12-point trend, +147.7% 81,474,366 77,704,188 75,708,889 73,104,692 70,828,226 69,718,096 61,935,870 50,606,147 41,612,395 34,169,410 33,916,559 32,898,392
Arus Kas 16
Data Arus Kas Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
D&A 11-point trend, +1249.6% $39M $76M $237M $129M $64M $43M $32M $26M $18M $3M $3M ·
Stock-based Comp 12-point trend, +286.1% $75M $75M $102M $110M $104M $70M $42M $33M $31M $35M $34M $19M
Deferred Tax 12-point trend, -3000.00 $-3.0K $-56M $-47M $-34M $377.0K $6M $9M $0 $199.0K $-199.0K $0 $0
Amort. of Intangibles 11-point trend, +24742000.00 $25M $61M $223M $117M $55M $37M $28M $23M $15M $0 $0 ·
Restructuring · · · · · · · · $0 · · ·
Other Non-cash 8-point trend, -513.8% $-85M $161M $177M · $105M $124M $70M $41M $20M · · ·
Operating Cash Flow 12-point trend, +1341.7% $711M $-108M $-158M $-357M $-251M $-194M $-99M $-28M $-10M $-104M $-124M $-57M
CapEx 12-point trend, +90.0% $9M $7M $28M $32M $28M $18M $14M $7M $3M $2M $3M $5M
Investing Cash Flow 12-point trend, -493.8% $-862M $44M $-177M $290M $219M $-562M $-387M $-43M $13M $104M $-21M $-145M
Net Debt Issued 2-point trend, +100.0% · · · · · · · · · $0 · $-49.0K
Stock Issued 7-point trend, -88.1% · · · · · $28M $324M $118M $0 $0 $0 $236M
Net Stock Activity 5-point trend, -88.1% · · · · · $28M $324M $118M · $0 · $236M
Financing Cash Flow 12-point trend, +39.6% $331M $256M $646M $168M $21M $669M $613M $132M $44M $968.0K $154M $237M
Net Change in Cash 12-point trend, +491.3% $203M $185M $314M $99M $-19M $-79M $126M $58M $53M $299.0K $8M $34M
Taxes Paid 12-point trend, +36854000.00 $37M $18M $14M $5M $8M $26M $2M $2M $1M $943.0K $111.0K $0
Free Cash Flow 11-point trend, +1233.9% $702M $-114M $-187M · $-280M $-212M $-112M $-35M $-13M $-105M $-127M $-62M
Profitabilitas 7
Data Profitabilitas Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
Operating Margin 11-point trend, +112.7% 50.1% -37.5% -46.9% · -69.5% -113.4% -78.6% -43.7% -33.1% -159.7% -454.6% -393.8%
Net Margin 11-point trend, +110.6% 39.4% -45.0% -66.8% · -97.3% -115.1% -82.0% -48.4% -40.6% -171.8% -463.6% -371.4%
Pretax Margin 11-point trend, +110.3% 40.2% -45.0% -74.2% · -96.2% -105.8% -78.2% -48.4% -40.0% -171.1% -462.3% -390.0%
EBITDA Margin 11-point trend, +113.3% 52.3% -28.1% -21.6% · -57.6% -102.0% -68.1% -33.8% -24.0% -159.7% -454.6% -393.8%
ROA 11-point trend, +176.7% 29.7% -20.2% -34.8% · -25.3% -22.9% -18.3% -17.0% -23.9% -44.8% -48.6% -38.6%
ROE 11-point trend, -669.1% -331.5% 33.8% 84.1% · -985.1% -88.3% -40.0% -34.8% -57.2% -82.2% -65.0% -43.1%
ROIC 11-point trend, +3393.6% 1044.7% 37.2% 74.0% · -87.4% -59.4% -27.8% -23.0% -21.7% -60.9% -52.3% -31.7%
Likuiditas & Solvabilitas 4
Data Likuiditas & Solvabilitas Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
Current Ratio 11-point trend, -76.4% 2.3 2.4 2.0 · 1.9 4.4 3.3 1.9 3.0 5.3 7.8 10.0
Quick Ratio 11-point trend, -77.7% 2.2 2.2 1.7 · 1.7 4.2 3.1 1.8 2.8 5.2 7.7 9.8
Debt / Equity 10-point trend, -433.5% -1.4 -0.3 -0.3 · 300.0 0.6 0.5 0.4 0.9 0.8 0.4 ·
LT Debt / Equity 9-point trend, -162.1% · -0.3 -0.3 · 196.0 0.6 0.5 0.4 0.9 0.8 0.4 ·
Efisiensi 3
Data Efisiensi Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
Asset Turnover 11-point trend, +622.2% 0.8 0.4 0.5 · 0.3 0.2 0.2 0.4 0.6 0.3 0.1 0.1
Inventory Turnover 2-point trend, -19.5% · · · · · · 0.7 · 0.9 · · ·
Receivables Turnover 11-point trend, +8.9% 10.2 5.1 5.9 · 6.0 6.1 5.0 4.9 6.0 4.6 4.7 9.3
Per Saham 5
Data Per Saham Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
Book Value / Share 11-point trend, -127.8% $-2.52 $-14.13 $-10.81 · $0.02 $6.91 $9.60 $6.93 $3.76 $3.50 $6.66 $9.07
Revenue / Share 5-point trend, +2350.3% $19.60 $10.50 $12.53 · $7.64 · · · · · · $0.80
Cash Flow / Share 5-point trend, +543.8% $8.05 $-1.40 $-2.12 · $-3.57 · · · · · · $-1.81
Cash / Share 11-point trend, +699.2% $12.09 $10.03 $7.85 · $2.68 $3.00 $4.65 $3.35 $2.69 $1.71 $1.71 $1.51
EPS (TTM) 12-point trend, +362.0% $7.78 $-4.73 $-8.37 $-7.79 $-7.43 $-6.64 $-4.27 $-3.21 $-3.21 $-3.21 $-3.21 $-2.97
Tingkat Pertumbuhan 3
Data Tingkat Pertumbuhan Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
Revenue YoY 5-point trend, +176.3% 114.5% -14.0% 34.2% 29.8% 41.4% · · · · · · ·
Revenue CAGR 3Y 3-point trend, +0.7% 35.3% 14.4% 35.0% · · · · · · · · ·
Revenue CAGR 5Y 35.4% · · · · · · · · · · ·
Valuasi (TTM) 13
Data Valuasi (TTM) Tahunan untuk PTCT
Metrik Tren 202520242023202220212020201920182017201620152014
Revenue TTM 12-point trend, +6755.4% $1.73B $807M $938M $699M $539M $381M $307M $265M $194M $83M $37M $25M
Net Income TTM 12-point trend, +828.1% $683M $-363M $-627M $-559M $-524M $-438M $-252M $-128M $-79M $-142M $-170M $-94M
Market Cap 11-point trend, +263.4% $6.19B $3.51B $2.09B · $2.82B $4.25B $2.97B $1.74B $694M $373M $1.10B $1.70B
Enterprise Value 10-point trend, +430.1% $4.53B $2.65B $1.49B · $2.48B $3.46B $2.60B $1.66B $648M $239M $855M ·
P/E 12-point trend, +156.0% 9.8 -9.5 -3.3 -4.9 -5.4 -9.2 -11.2 -10.7 -5.2 -3.4 -10.1 -17.4
P/S 11-point trend, -94.7% 3.6 4.3 2.2 · 5.2 11.2 9.7 6.6 3.6 4.5 29.9 67.5
P/B 11-point trend, -628.2% -30.1 -3.2 -2.5 · 1961.8 8.8 5.0 5.0 4.4 3.1 4.9 5.7
P / Cash Flow 11-point trend, +129.3% 8.7 -32.6 -13.2 · -11.2 -21.9 -30.2 -62.8 -69.0 -3.6 -8.8 -29.7
P / FCF 11-point trend, +132.0% 8.8 -30.7 -11.2 · -10.1 -20.1 -26.5 -50.0 -52.7 -3.5 -8.6 -27.5
EV / EBITDA 10-point trend, +197.8% 5.0 -11.7 -7.4 · -8.0 -8.9 -12.5 -18.6 -13.9 -1.8 -5.1 ·
EV / FCF 10-point trend, +195.9% 6.5 -23.2 -8.0 · -8.9 -16.3 -23.2 -47.9 -49.2 -2.3 -6.7 ·
EV / Revenue 10-point trend, -88.7% 2.6 3.3 1.6 · 4.6 9.1 8.5 6.3 3.3 2.9 23.2 ·
Earnings Yield 12-point trend, +278.4% 10.2% -10.5% -30.4% -20.4% -18.6% -10.9% -8.9% -9.3% -19.2% -29.4% -9.9% -5.7%

Laporan Keuangan Laporan laba rugi, neraca, arus kas — tahunan, 5 tahun terakhir

Laporan Laba Rugi
2025-12-312024-12-312023-12-312022-12-312021-12-31
Pendapatan $1.73B$807M$938M$699M$539M
Margin Operasi % 50.1%-37.5%-46.9%-69.5%
Laba Bersih $683M$-363M$-627M$-559M$-524M
EPS Dilusian $7.78$-4.73$-8.37$-7.79$-7.43
Neraca
2025-12-312024-12-312023-12-312022-12-312021-12-31
Utang / Ekuitas -1.4-0.3-0.3300.0
Rasio Lancar 2.32.42.01.9
Rasio Cepat 2.22.21.71.7
Arus Kas
2025-12-312024-12-312023-12-312022-12-312021-12-31
Arus Kas Bebas $702M$-114M$-187M$-280M

Sinyal Perdagangan Sinyal beli/jual terbaru dengan harga masuk dan rasio risiko/imbalan

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Pemilik institusional (13F) 405 pengaju · $5.4B total · Per tanggal 30 Juni 2026

Institusi yang melaporkan kepemilikan saham ini dalam SEC Form 13F triwulanan mereka. Hanya posisi panjang; satu pengaju dapat muncul dua kali untuk leg opsi terpisah. Kaki put/call offset yang besar biasanya mencerminkan pembuatan pasar atau inventaris yang dilindungi, bukan keyakinan arah.

Aktivitas institusional — Q2 2026 vs kuartal sebelumnya
Posisi baru Posisi yang keluar Meningkat Menurun Perubahan bersih saham
84 (+17 vs Kuartal sebelumnya) 43 (-7 vs Kuartal sebelumnya) 133 (-6 vs Kuartal sebelumnya) 109 (+6 vs Kuartal sebelumnya) -7.1M

Dibandingkan dengan Q1 2026. Pengajuan Formulir 13F SEC jatuh tempo dalam waktu 45 hari setelah akhir kuartal ditambah kelonggaran singkat untuk pengaju terlambat — kuartal yang masih dalam jangka waktu tersebut dilewati demi pasangan terakhir yang dilaporkan sepenuhnya.

Institusi Nilai Saham % dari 13F yang dilacak Tipe
RTW INVESTMENTS, LP $631.875.072 7.746.415 11,70% Saham
JANUS HENDERSON GROUP PLC $479.178.655 7.034.622 8,87% Saham
VANGUARD PORTFOLIO MANAGEMENT LLC $401.986.014 4.928.111 7,44% Saham
STATE STREET CORP $375.136.515 4.598.952 6,95% Saham
VANGUARD CAPITAL MANAGEMENT LLC $305.000.589 3.739.127 5,65% Saham
WELLINGTON MANAGEMENT GROUP LLP $292.435.873 3.585.091 5,42% Saham
WESTFIELD CAPITAL MANAGEMENT CO LP $159.563.645 1.956.156 2,95% Saham
GEODE CAPITAL MANAGEMENT, LLC $155.132.041 1.901.417 2,87% Saham
Hood River Capital Management LLC $141.818.662 1.738.613 2,63% Saham
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC $140.519.660 1.722.688 2,60% Saham
TANG CAPITAL MANAGEMENT LLC $122.355.000 1.500.000 2,27% Saham
Driehaus Capital Management LLC $117.469.528 1.440.107 2,18% Saham
Jefferies Financial Group Inc. $110.693.916 1.357.042 2,05% Saham
FULLER & THALER ASSET MANAGEMENT, INC. $94.361.749 1.156.819 1,75% Saham
Pictet Asset Management Holding SA $93.629.635 1.147.844 1,73% Saham
ARMISTICE CAPITAL, LLC $87.393.690 1.071.395 1,62% Saham
Blue Sparrow, LLC /DE $85.705.599 1.050.700 1,59% Saham
D. E. Shaw & Co., Inc. $77.478.857 949.845 1,43% Saham
Palo Alto Investors LP $74.950.268 918.846 1,39% Saham
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $64.449.436 790.112 1,19% Saham
RENAISSANCE TECHNOLOGIES LLC $59.015.895 723.500 1,09% Saham
Boston Partners $57.080.953 699.871 1,06% Saham
FMR LLC $56.956.987 698.259 1,05% Saham
BANK OF AMERICA CORP /DE/ $56.350.840 690.828 1,04% Saham
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP $53.377.940 654.382 0,99% Saham
DIMENSIONAL FUND ADVISORS LP $51.486.821 631.199 0,95% Saham
VANGUARD FIDUCIARY TRUST CO $47.953.943 587.887 0,89% Saham
Ensign Peak Advisors, Inc $41.442.128 508.056 0,77% Saham
AMERICAN CENTURY COMPANIES INC $40.866.277 500.995 0,76% Saham
MANUFACTURERS LIFE INSURANCE COMPANY, THE $36.050.432 441.957 0,67% Saham
Parkman Healthcare Partners LLC $35.539.315 435.691 0,66% Saham
LOOMIS SAYLES & CO L P $35.387.921 433.835 0,66% Saham
Defilade Capital Management, L.P. $35.376.827 433.699 0,66% Saham
GOLDMAN SACHS GROUP INC $34.153.522 418.702 0,63% Saham
SUSQUEHANNA INTERNATIONAL GROUP, LLP $32.274.149 395.662 0,60% Saham
BNP PARIBAS FINANCIAL MARKETS $30.892.190 378.720 0,57% Saham
Qube Research & Technologies Ltd $25.398.777 311.374 0,47% Saham
ARMISTICE CAPITAL, LLC $24.471.000 300.000 0,45% Opsi beli
Public Sector Pension Investment Board $23.249.326 285.023 0,43% Saham
SEGALL BRYANT & HAMILL, LLC $22.165.424 271.735 0,41% Saham
CITADEL ADVISORS LLC $20.338.011 249.332 0,38% Saham
MORGAN STANLEY $18.990.210 232.808 0,35% Saham
Boxer Capital Management, LLC $16.314.000 200.000 0,30% Saham
RHUMBLINE ADVISERS $15.718.994 192.706 0,29% Saham
AMERIPRISE FINANCIAL INC $13.904.178 170.457 0,26% Saham
PRUDENTIAL FINANCIAL INC $13.746.176 168.520 0,25% Saham
BlackRock, Inc. $13.589.562 166.600 0,25% Saham
Rock Springs Capital Management LP $13.238.648 162.298 0,25% Saham
Hudson Bay Capital Management LP $13.033.091 159.778 0,24% Saham
Russell Investments Group, Ltd. $12.687.724 155.544 0,23% Saham
Schonfeld Strategic Advisors LLC $12.025.457 147.425 0,22% Saham
MARSHALL WACE, LLP $11.724.301 143.733 0,22% Saham
Swiss National Bank $11.539.300 141.465 0,21% Saham
Universal- Beteiligungs- und Servicegesellschaft mbH $11.063.583 135.633 0,20% Saham
Legal & General Group Plc $10.362.979 127.044 0,19% Saham
CITIGROUP INC $9.272.143 113.671 0,17% Saham
FIRST TRUST ADVISORS LP $9.246.285 113.354 0,17% Saham
Longaeva Partners L.P. $9.119.771 111.803 0,17% Saham
JUPITER ASSET MANAGEMENT LTD $8.927.184 109.442 0,17% Saham
SCHRODER INVESTMENT MANAGEMENT GROUP $8.215.404 100.716 0,15% Saham
SECTOR GAMMA AS $8.157.000 100.000 0,15% Saham
WCM INVESTMENT MANAGEMENT, LLC $7.651.184 93.799 0,14% Saham
PANAGORA ASSET MANAGEMENT INC $7.256.141 88.956 0,13% Saham
VOYA INVESTMENT MANAGEMENT LLC $7.239.501 88.752 0,13% Saham
ALLIANCEBERNSTEIN L.P. $7.217.488 105.937 0,13% Saham
Aquatic Capital Management LLC $6.808.648 83.470 0,13% Saham
XTX Topco Ltd $6.682.459 81.923 0,12% Saham
MOORE CAPITAL MANAGEMENT, LP $6.165.713 75.588 0,11% Saham
PINNACLE ASSOCIATES LTD $5.745.383 70.435 0,11% Saham
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM $5.744.722 84.320 0,11% Saham
VANGUARD ASSET MANAGEMENT, Ltd $5.614.300 68.828 0,10% Saham
Capricorn Fund Managers Ltd $5.212.323 63.900 0,10% Saham
SUSQUEHANNA INTERNATIONAL GROUP, LLP $5.000.241 61.300 0,09% Opsi beli
INTECH INVESTMENT MANAGEMENT LLC $4.696.882 57.581 0,09% Saham
ExodusPoint Capital Management, LP $4.672.166 57.278 0,09% Saham
LOS ANGELES CAPITAL MANAGEMENT LLC $4.561.884 55.926 0,08% Saham
BARCLAYS PLC $4.169.858 51.120 0,08% Saham
ORBIMED ADVISORS LLC $4.005.087 49.100 0,07% Saham
MetLife Investment Management, LLC $3.932.653 48.212 0,07% Saham
Point72 Europe (London) LLP $3.829.919 62.407 0,07% Saham
MILLENNIUM MANAGEMENT LLC $3.792.516 46.494 0,07% Saham
Phocas Financial Corp. $3.766.087 46.170 0,07% Saham
MARTINGALE ASSET MANAGEMENT L P $3.627.826 44.475 0,07% Saham
Quadrature Capital Ltd $3.589.488 44.005 0,07% Saham
SUSQUEHANNA INTERNATIONAL GROUP, LLP $3.531.981 43.300 0,07% Opsi jual
STATE OF WISCONSIN INVESTMENT BOARD $3.436.299 42.127 0,06% Saham
CREDIT AGRICOLE S A $3.344.370 41.000 0,06% Saham
Fisher Asset Management, LLC $3.322.345 40.730 0,06% Saham
HSBC HOLDINGS PLC $3.200.425 38.732 0,06% Saham
NEW YORK STATE COMMON RETIREMENT FUND $3.134.490 38.427 0,06% Saham
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. $3.114.179 38.178 0,06% Saham
CenterBook Partners LP $3.082.938 37.795 0,06% Saham
Rafferty Asset Management, LLC $3.069.805 37.634 0,06% Saham
FIFTH THIRD BANCORP $3.044.843 37.328 0,06% Saham
BURNEY CO/ $3.044.192 37.320 0,06% Saham
Vanguard Global Advisers, LLC $3.033.180 37.185 0,06% Saham
Arrowpoint Investment Partners (Singapore) Pte. Ltd. $3.007.731 36.873 0,06% Saham
Louisiana State Employees Retirement System $2.969.148 36.400 0,05% Saham
JANE STREET GROUP, LLC $2.854.950 35.000 0,05% Opsi jual
CASTLEARK MANAGEMENT LLC $2.765.223 33.900 0,05% Saham

Orang dalam perusahaan 33 orang dalam · 13 pejabat · 14 direktur

Orang Dalam Peran Aktivitas terakhir Saham dimiliki Beli 12m Jual 12m Bersih 12m
Stuart Walter Peltz Chief Executive Officer 1 Feb. 2022 S 38.728 0 0 $0
Pierre Gravier CHIEF FINANCIAL OFFICER 14 Juli 2026 S 83.986 0 1 $-280.743
Emily Luisa Hill Chief Financial Officer 1 Feb. 2022 S 37.169 0 0 $0
Shane William Charles Kovacs Chief Financial Officer 9 Mei 2017 M 37.850 0 0 $0
Claudia De Oliveira Ribeiro Hirawat President 15 Jan. 2015 M 39.247 0 0 $0
Marcio Souza Chief Operating Officer 10 Feb. 2020 M 6.744 0 0 $0
Neil Gregory Almstead CHIEF TECHNICAL OPS OFFICER 9 Juli 2026 M 60.299 0 20 $-9.184.852
Mark Elliott Boulding EXEC. VP AND CLO 6 Juli 2026 M 105.272 0 12 $-1.254.986
Christine Marie Utter SVP, CHIEF ACCOUNTING OFFICER 17 Juni 2026 M 70.199 0 1 $-1.487.474
Eric Pauwels CHIEF BUSINESS OFFICER 10 Juni 2026 S 73.411 0 28 $-7.477.160
Mark Rothera Chief Commercial Officer 24 Mei 2017 M 33.739 0 0 $0
Tuyen Ong Chief Medical Officer 3 Jan. 2017 A 6.000 0 0 $0
Robert J. Spiegel Chief Medical Officer 4 Jan. 2016 A 3.239 0 0 $0
Hege Elisabeth Sollie-Zetlmayer Direktur 28 Juli 2026 A 52.526 0 0 $0
Mary L. Smith Direktur 9 Juli 2026 M 21.813 0 2 $-1.425.060
Stephanie Okey Direktur 7 Jan. 2022 A 4.163 0 0 $0
Emma Reeve Direktur 7 Jan. 2022 A 7.528 0 0 $0
Allan Steven Jacobson Direktur 7 Jan. 2022 A 8.348 0 0 $0
Dawn Svoronos Direktur 7 Jan. 2022 A 29.755 0 0 $0
Jerome B Zeldis Direktur 7 Jan. 2022 A 6.500 0 0 $0
Cameron Geoffrey Mcdonough Direktur 3 Jan. 2017 A 0 0 $0
Adam Koppel Direktur 3 Jan. 2017 A 2.333.333 0 0 $0
Ronald C Renaud JR Direktur 3 Jan. 2017 A 0 0 $0
Richard Aldrich Direktur 8 Juni 2015 M 0 0 0 $0
Michael L Kranda Direktur 16 Maret 2015 S 2.242 0 0 $0
Axel Bolte Direktur 25 Juni 2013 P 20.000 0 0 $0
HBM Healthcare Investments (Cayman) Ltd. Pemilik 10% 17 Des. 2013 S 2.441.504 0 0 $0
Matthew B. Klein 4 Agu 2026 S 383.868 0 1 $-705.722
Michael Schmertzler 2 Jan. 2026 A 163.266 0 0 $0
Glenn Steele JR MD PHD 2 Jan. 2026 A 22.500 0 1 $-916.200
David P Southwell 2 Jan. 2026 A 20.850 0 0 $0
Complete Pharma Holdings II, LLC 28 April 2017 J 0 0 0 $0
CREDIT SUISSE/ 25 Juni 2013 C 2.256.882 0 0 $0

Orang dalam dari pengajuan SEC Form 3/4/5; bersih = hanya P/S pasar terbuka

Aktivis & pemilik 5%+ 3 saham

Investor yang mengajukan Jadwal 13D SEC — kepemilikan manfaat di atas 5% dengan niat untuk memengaruhi penerbit (kepemilikan aktivis, kampanye dewan, M&A). Setiap baris menunjukkan status terbaru yang diketahui dari posisi pengaju tersebut.

Pengaju Diajukan Kepemilikan Status Tujuan Pengajuan
Brookside Capital Partners Fund, L.P., Brookside Capital Trading Fund, L.P. ×5 pengajuan 30 Jan. 2015 Pengajuan awal SEC
HBM Healthcare Investments (Cayman) Ltd. (“HBM”) ×2 pengajuan 12 Nov. 2014 Pengajuan awal SEC
HBM Healthcare Investments (Cayman) Ltd. 5 Juli 2013 Pengajuan awal SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Kepemilikan ETF Dimiliki oleh 88 ETF

Bobot mencerminkan kepemilikan ekuitas langsung (N-PORT) saja; dana berbasis leverage atau derivatif mungkin memiliki eksposur swap tambahan yang tidak ditampilkan.

Dana Bobot Unit Per tanggal Sumber
BBP · ETFis Series Trust I 1,37% 12.510 NS 30 April 2026 N-PORT
SIXS · EXCHANGE TRADED CONCEPTS TRUST 1,30% 22.380 NS 31 Mei 2026 N-PORT
GURU · Global X Funds 1,03% 9.268 NS 30 April 2026 N-PORT
LABU · Direxion Shares ETF Trust 0,93% 73.928 NS 30 April 2026 N-PORT
VAMO · Cambria ETF Trust 0,83% 10.625 NS 30 April 2026 N-PORT
VMAX · Lattice Strategies Trust 0,72% 5.120 NS 30 April 2026 N-PORT
FNY · First Trust Exchange-Traded AlphaDE… 0,51% 40.257 NS 30 April 2026 N-PORT
MMSC · First Trust Exchange-Traded Fund VI… 0,49% 3.490 NS 31 Mei 2026 N-PORT
CLSE · Trust for Professional Managers 0,49% 40.488 NS 31 Mei 2026 N-PORT
PSC · Principal Exchange-Traded Funds 0,47% 135.289 NS 30 Juni 2026 N-PORT
HQGO · Lattice Strategies Trust 0,43% 3.203 NS 30 April 2026 N-PORT
OASC · Unified Series Trust 0,40% 4.569 NS 31 Mei 2026 N-PORT
BRNY · EA Series Trust 0,40% 34.057 NS 30 April 2026 N-PORT
MSSM · MORGAN STANLEY PATHWAY FUNDS 0,34% 35.034 NS 31 Mei 2026 N-PORT
ESSC · Strategy Shares 0,34% 1.335 NS 30 April 2026 N-PORT
BIB · ProShares Trust 0,31% 3.062 NS 31 Mei 2026 N-PORT
FSCC · Federated Hermes ETF Trust 0,31% 11.451 NS 31 Mei 2026 N-PORT
GSSC · Goldman Sachs ETF Trust 0,30% 39.411 NS 31 Mei 2026 N-PORT
SAA · ProShares Trust 0,26% 961 NS 31 Mei 2026 N-PORT
ROUS · Lattice Strategies Trust 0,25% 22.443 NS 30 April 2026 N-PORT
BBSC · J.P. Morgan Exchange-Traded Fund Tr… 0,24% 27.276 NS 30 April 2026 N-PORT
BKSE · BNY Mellon ETF Trust 0,23% 2.877 NS 30 April 2026 N-PORT
AFSM · First Trust Exchange-Traded Fund VI… 0,23% 3.003 NS 31 Mei 2026 N-PORT
FNX · First Trust Exchange-Traded AlphaDE… 0,20% 39.967 NS 30 April 2026 N-PORT
RSSL · Global X Funds 0,16% 34.125 NS 30 April 2026 N-PORT
FAD · First Trust Exchange-Traded AlphaDE… 0,15% 11.071 NS 30 April 2026 N-PORT
ITWO · ProShares Trust 0,15% 3.710 NS 31 Mei 2026 N-PORT
FSMD · FIDELITY COVINGTON TRUST 0,14% 49.932 NS 30 April 2026 N-PORT
SMDX · Tidal Trust III 0,13% 2.579 NS 30 April 2026 N-PORT
SXQG · EXCHANGE TRADED CONCEPTS TRUST 0,13% 1.182 NS 31 Mei 2026 N-PORT
SCHA · SCHWAB STRATEGIC TRUST 0,13% 386.068 NS 31 Mei 2026 N-PORT
DFAS · Dimensional ETF Trust 0,09% 190.421 NS 30 April 2026 N-PORT
UWM · ProShares Trust 0,09% 2.899 NS 31 Mei 2026 N-PORT
FHLC · FIDELITY COVINGTON TRUST 0,08% 33.415 NS 30 April 2026 N-PORT
FYEE · Fidelity Greenwood Street Trust 0,07% 1.913 NS 30 April 2026 N-PORT
URTY · ProShares Trust 0,06% 2.936 NS 31 Mei 2026 N-PORT
FBUF · Fidelity Greenwood Street Trust 0,05% 154 NS 30 April 2026 N-PORT
AFMC · First Trust Exchange-Traded Fund VI… 0,05% 1.112 NS 31 Mei 2026 N-PORT
TILT · FlexShares Trust 0,04% 13.552 NS 30 April 2026 N-PORT
HDG · ProShares Trust 0,03% 74 NS 31 Mei 2026 N-PORT
DCOR · Dimensional ETF Trust 0,02% 6.829 NS 30 April 2026 N-PORT
DFAC · Dimensional ETF Trust 0,01% 95.919 NS 30 April 2026 N-PORT
ONEQ · Fidelity Commonwealth Trust 0,01% 17.796 NS 31 Mei 2026 N-PORT
SCHB · SCHWAB STRATEGIC TRUST 0,01% 47.658 NS 31 Mei 2026 N-PORT
AVSU · AMERICAN CENTURY ETF TRUST 0,01% 506 NS 31 Mei 2026 N-PORT
AVUQ · AMERICAN CENTURY ETF TRUST 0,01% 273 NS 31 Mei 2026 N-PORT
DFUS · Dimensional ETF Trust 0,01% 21.258 NS 30 April 2026 N-PORT
FHEQ · Fidelity Greenwood Street Trust 0,01% 861 NS 30 April 2026 N-PORT
DFAU · Dimensional ETF Trust 0,00% 7.872 NS 30 April 2026 N-PORT
FTLS · First Trust Exchange-Traded Fund III -0,10% -33.590 NS 30 April 2026 N-PORT