EWTX Edgewise Therapeutics, Inc. - Common Stock
$44,20
Prezzo · Ago 18, 2026
Fondamentali al Ago 6, 2026
Intervallo 52 sett.
$14–$48
88% of range
Rating Analisti
BUY
19 analysts
Prezzo Obiettivo
$51
+16% upside
P/E (TTM)
-27.4
ROE
-30.2%
Margine di Profitto Netto
—
EWTX Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane
Prezzo
$44.20
Capitalizzazione di Mercato
$4.75B
P/E (TTM)
-27.4
EPS (TTM)
$-1.63
Ricavi (TTM)
—
Rendimento div.
—
ROE
-30.2%
D/E Debito/Patrimonio
—
Intervallo 52 sett.
$14 – $48
EWTX Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione
Configure
Performance decennale Andamento di ricavi, utile netto, margini e EPS
Ricavi e Utile Netto
—
EPS
$-1.63
2020-12-31
→
2025-12-31
Flusso di cassa libero
$-144M
2021-12-31
→
2025-12-31
Margini
—
Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?
Metrica
Tendenza 5 anni
EWTX
Mediana dei peer
P/E (TTM)
-27.4
38.7
P/B
9.1
3.8
Price / FCF (Prezzo / FCF)
-33.0
—
Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC
Metrica
Tendenza 5 anni
EWTX
Mediana dei peer
ROA
-32.3%
-6.4%
ROE
-30.2%
-16.8%
ROIC
-36.6%
—
Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio
Metrica
Tendenza 5 anni
EWTX
Mediana dei peer
Current Ratio (Rapporto corrente)
19.9
12.8
Quick Ratio
2.2
—
Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y
Metrica
Tendenza 5 anni
EWTX
Mediana dei peer
Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti
Metrica
Tendenza 5 anni
EWTX
Mediana dei peer
EWTX Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo
COMPRA
19 analisti
- Acquisto forte 7 36,8%
- Compra 9 47,4%
- Mantieni 3 15,8%
- Vendi 0 0,0%
- Vendita forte 0 0,0%
Target Price a 12 Mesi
13 analisti · 2026-08-18
Mediana
$52.00
Ora
$44.20
Basso
$36.00
Alto
$66.00
Target mediano
$52.00
+17,7%
Target medio
$51.15
+15,7%
Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili
Sorpresa media
0.01%
| Periodo | EPS Actual | EPS Stimato | Sorpresa |
|---|---|---|---|
| 30 Giugno 2026 | $-0.53 | $-0.48 | -0.05% |
| 31 Marzo 2026 | $-0.46 | $-0.50 | 0.04% |
| 31 Dicembre 2025 | $-0.47 | $-0.44 | -0.03% |
| 30 Settembre 2025 | $-0.39 | $-0.41 | 0.02% |
| 30 Giugno 2025 | $-0.34 | $-0.42 | 0.08% |
| 31 Marzo 2025 | $-0.43 | $-0.44 | 0.01% |
Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore
| Ticker | Capitalizzazione di Mercato | P/E | Rev YoY | Margine Netto | ROE | Margine lordo |
|---|---|---|---|---|---|---|
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| BLTE | — | — | — | — | — | — |
| LGND | $3.74B | 30.8 | 60.4% | 46.4% | 13.5% | — |
| DFTX | $1.32B | -6.5 | 212.0% | — | -71.0% | — |
| AMRX | — | 57.3 | 8.1% | 2.4% | -80.0% | 36.9% |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| MANE | — | — | — | — | 82.6% | — |
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario
Conto Economico 12
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| R&D Expense | $151M | $127M | $91M | $54M | $32M | $15M | |
| SG&A Expense | $40M | $32M | $23M | $18M | $11M | $2M | |
| Operating Expenses | $191M | $159M | $114M | $72M | $43M | $17M | |
| Operating Income | $-191M | $-159M | $-114M | $-72M | $-43M | $-17M | |
| Pretax Income | $-168M | $-134M | $-100M | · | · | · | |
| Income Tax | $4.0K | $3.0K | $4.0K | $0 | $0 | · | |
| Net Income | $-168M | $-134M | $-100M | $-68M | $-43M | $-17M | |
| EPS (Basic) | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 | $-23.17 | |
| EPS (Diluted) | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 | $-23.17 | |
| Shares (Basic) | 102,930,744 | 92,414,626 | 63,723,600 | 53,593,753 | 37,526,332 | 739,004 | |
| Shares (Diluted) | 102,930,744 | 92,414,626 | 63,723,600 | 53,593,753 | 37,526,332 | 739,004 | |
| EBITDA | $-191M | $-159M | $-114M | $-72M | $-43M | · |
Stato Patrimoniale 21
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $61M | $42M | $86M | $22M | $16M | $105M | |
| Prepaid Expense | $13M | $5M | $9M | $5M | $3M | $551.0K | |
| Current Assets | $543M | $475M | $327M | $357M | $284M | $130M | |
| PP&E (Net) | $8M | $10M | $10M | $9M | $912.0K | $516.0K | |
| PP&E (Gross) | $15M | $14M | $13M | $10M | $2M | $946.0K | |
| Accum. Depreciation | $7M | $5M | $3M | $1M | $702.0K | $430.0K | |
| Other Non-current Assets | · | $262.0K | $348.0K | $251.0K | $548.0K | $975.0K | |
| Total Assets | $553M | $487M | $340M | $367M | $285M | $131M | |
| Accounts Payable | $6M | $6M | $4M | $6M | $4M | $2M | |
| Accrued Liabilities | $8M | $7M | $6M | $6M | $4M | $2M | |
| Current Liabilities | $27M | $24M | $17M | $17M | $11M | $4M | |
| Capital Leases | $3M | $4M | $4M | $4M | · | · | |
| Other Non-current Liabilities | · | · | · | · | $329.0K | · | |
| Total Liabilities | $30M | $28M | $21M | $20M | $11M | $4M | |
| Common Stock | $10.0K | $9.0K | $7.0K | $6.0K | $5.0K | · | |
| Paid-in Capital | $1.07B | $837M | $563M | $493M | $352M | $727.0K | |
| Retained Earnings | $-546M | $-379M | $-245M | $-145M | $-77M | $-34M | |
| AOCI | $677.0K | $420.0K | $99.0K | $-1M | $-514.0K | · | |
| Stockholders' Equity | $522M | $459M | $319M | $347M | $274M | $-33M | |
| Liabilities + Equity | $553M | $487M | $340M | $367M | $285M | $131M | |
| Shares Outstanding | 106,249,579 | 94,838,466 | 70,453,342 | 63,257,376 | 49,500,308 | 1,009,479 |
Flusso di cassa 9
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Stock-based Comp | $35M | $25M | $18M | $11M | $4M | $354.0K | |
| Operating Cash Flow | $-144M | $-109M | $-92M | $-53M | $-34M | $-15M | |
| CapEx | $256.0K | $1M | $6M | $6M | $668.0K | $203.0K | |
| Investing Cash Flow | $-33M | $-185M | $103M | $-71M | $-242M | $-24M | |
| Stock Issued | $187M | $239M | $53M | $129M | · | · | |
| Net Stock Activity | $187M | $239M | $53M | $129M | · | · | |
| Financing Cash Flow | $196M | $249M | $53M | $130M | $186M | $120M | |
| Net Change in Cash | $19M | $-44M | $64M | $6M | $-89M | $81M | |
| Free Cash Flow | $-144M | $-110M | $-98M | $-58M | $-34M | · |
Redditività 3
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| ROA | -32.3% | -32.4% | -28.3% | -20.7% | -20.6% | · | |
| ROE | -30.2% | -28.2% | -32.9% | -19.1% | -15.3% | · | |
| ROIC | -36.6% | · | · | · | · | · |
Liquidità e Solvibilità 2
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Current Ratio | 19.9 | 19.9 | 19.5 | 21.5 | 27.0 | · | |
| Quick Ratio | 2.2 | 1.7 | 5.1 | 1.3 | 1.5 | · |
Valutazione (TTM) 8
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 |
|---|---|---|---|---|---|---|---|
| Net Income TTM | $-168M | $-134M | $-100M | $-68M | $-43M | · | |
| Market Cap | $2.64B | $2.53B | $771M | $566M | $756M | · | |
| P/E | -15.2 | -18.4 | -7.0 | -7.1 | -13.4 | · | |
| P/B | 5.0 | 5.5 | 2.4 | 1.6 | 2.8 | · | |
| P / Tangible Book | 5.0 | 5.5 | 2.4 | 1.6 | 2.8 | · | |
| P / Cash Flow | -18.3 | -23.2 | -8.4 | -10.7 | -22.6 | · | |
| P / FCF | -18.3 | -22.9 | -7.9 | -9.7 | -22.1 | · | |
| Earnings Yield | -6.6% | -5.4% | -14.3% | -14.1% | -7.5% | · |
Conto Economico 10
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $48M | $43M | $44M | $37M | $34M | $37M | $36M | $32M | $31M | $28M | $24M | $20M | $20M | $17M | $14M | $12M | |
| SG&A Expense | $14M | $11M | $12M | $9M | $9M | $9M | $9M | $8M | $7M | $7M | $6M | $6M | $6M | $5M | $4M | $4M | |
| Operating Expenses | $62M | $54M | $56M | $47M | $43M | $46M | $46M | $40M | $38M | $35M | $29M | $25M | $26M | $22M | $18M | $16M | |
| Operating Income | $-62M | $-54M | $-56M | $-47M | $-43M | $-46M | $-46M | $-40M | $-38M | $-35M | $-29M | $-25M | $-26M | $-22M | $-18M | $-16M | |
| Net Income | $-57M | $-49M | $-50M | $-41M | $-36M | $-41M | $-40M | $-34M | $-31M | $-29M | $-26M | $-21M | $-23M | $-19M | $-17M | $-16M | |
| EPS (Basic) | $-0.53 | $-0.46 | $-0.47 | $-0.39 | $-0.34 | $-0.43 | $-0.42 | $-0.36 | $-0.34 | $-0.33 | $-0.41 | $-0.34 | $-0.36 | $-0.30 | $-0.34 | $-0.32 | |
| EPS (Diluted) | $-0.53 | $-0.46 | $-0.47 | $-0.39 | $-0.34 | $-0.43 | $-0.42 | $-0.36 | $-0.34 | $-0.33 | $-0.41 | $-0.34 | $-0.36 | $-0.30 | $-0.34 | $-0.32 | |
| Shares (Basic) | 107,669,774 | 107,116,709 | -202,632,581 | 105,492,779 | 104,940,493 | 95,130,053 | -182,481,383 | 93,813,346 | 93,515,356 | 87,567,307 | 63,459,560 | 63,380,430 | 63,265,800 | -97,418,492 | 51,844,904 | 49,622,752 | |
| Shares (Diluted) | 107,669,774 | 107,116,709 | -202,632,581 | 105,492,779 | 104,940,493 | 95,130,053 | -182,481,383 | 93,813,346 | 93,515,356 | 87,567,307 | 63,459,560 | 63,380,430 | 63,265,800 | -97,418,492 | 51,844,904 | 49,622,752 | |
| EBITDA | $-62M | $-54M | · | $-47M | $-43M | $-46M | · | $-40M | $-38M | $-35M | $-29M | $-25M | $-26M | · | $-18M | $-16M |
Stato Patrimoniale 24
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $72M | $33M | $61M | $46M | $43M | $50M | $42M | $45M | $43M | $30M | $33M | $32M | $48M | $22M | $110M | $18M | |
| Prepaid Expense | $6M | $10M | $13M | $11M | $9M | $7M | $5M | $7M | $8M | $9M | $8M | $7M | $5M | $5M | $5M | $5M | |
| Current Assets | $472M | $510M | $543M | $574M | $603M | $443M | $475M | $499M | $519M | $541M | $298M | $317M | $333M | $357M | $370M | $253M | |
| PP&E (Net) | $7M | $7M | $8M | $8M | $9M | $9M | $10M | $10M | $10M | $10M | $11M | $11M | $10M | $9M | $5M | $2M | |
| PP&E (Gross) | $15M | $15M | $15M | $14M | $14M | $14M | $14M | $14M | $13M | $13M | $13M | $13M | $12M | $10M | $6M | $3M | |
| Accum. Depreciation | $8M | $7M | $7M | $6M | $6M | $5M | $5M | $4M | $4M | $3M | $2M | $2M | $1M | $1M | $977.0K | $882.0K | |
| Other Non-current Assets | · | · | · | · | · | $695.0K | $262.0K | $262.0K | $262.0K | · | $467.0K | $419.0K | $251.0K | $251.0K | $264.0K | $447.0K | |
| Total Assets | $480M | $519M | $553M | $583M | $613M | $454M | $487M | $511M | $532M | $554M | $311M | $331M | $346M | $367M | $377M | $257M | |
| Accounts Payable | $5M | $7M | $6M | $6M | $8M | $9M | $6M | $6M | $7M | $5M | $5M | $4M | $4M | $6M | $6M | $3M | |
| Accrued Liabilities | $5M | $9M | $8M | $6M | $6M | $7M | $7M | $6M | $5M | $6M | $6M | $7M | $6M | $6M | $5M | $4M | |
| Short-term Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $7.0K | · | |
| Current Liabilities | $29M | $23M | $27M | $22M | $21M | $21M | $24M | $19M | $17M | $15M | $16M | $14M | $13M | $17M | $13M | $9M | |
| Capital Leases | $3M | $3M | $3M | $3M | $3M | $4M | $4M | $3M | $4M | $4M | $5M | $5M | $5M | $4M | $2M | $2M | |
| Other Non-current Liabilities | · | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $192.0K | |
| Total Liabilities | $32M | $25M | $30M | $25M | $24M | $25M | $28M | $22M | $21M | $19M | $21M | $19M | $18M | $20M | $16M | $11M | |
| Long-term Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $59.0K | · | |
| Total Debt | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $7.0K | · | |
| Common Stock | $10.0K | $10.0K | $10.0K | $10.0K | $10.0K | $9.0K | $9.0K | $9.0K | $9.0K | $9.0K | $6.0K | $6.0K | $6.0K | $6.0K | $6.0K | $5.0K | |
| Paid-in Capital | $1.10B | $1.09B | $1.07B | $1.05B | $1.04B | $849M | $837M | $827M | $816M | $809M | $505M | $501M | $497M | $493M | $489M | $356M | |
| Retained Earnings | $-653M | $-595M | $-546M | $-496M | $-455M | $-419M | $-379M | $-339M | $-305M | $-273M | $-215M | $-189M | $-167M | $-145M | $-125M | $-108M | |
| AOCI | $-500.0K | $-252.0K | $677.0K | $701.0K | $204.0K | $401.0K | $420.0K | $1M | $-1M | $-861.0K | $-424.0K | $-547.0K | $-251.0K | $-1M | $-2M | $-2M | |
| Stockholders' Equity | $448M | $493M | $522M | $559M | $589M | $430M | $459M | $489M | $510M | $535M | $290M | $311M | $329M | $347M | $361M | $246M | |
| Liabilities + Equity | $480M | $519M | $553M | $583M | $613M | $454M | $487M | $511M | $532M | $554M | $311M | $331M | $346M | $367M | $377M | $257M | |
| Shares Outstanding | 107,776,380 | 107,481,522 | 106,249,579 | 105,761,949 | 105,341,296 | 95,205,683 | 94,838,466 | 94,408,911 | 93,643,341 | 93,284,528 | 63,460,939 | 63,458,932 | 63,274,732 | 63,257,376 | 63,208,828 | 49,780,365 |
Flusso di cassa 9
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $9M | $9M | $10M | $8M | $8M | $9M | $8M | $7M | $5M | $5M | $5M | $4M | $4M | $4M | $3M | $2M | |
| Operating Cash Flow | $-42M | $-43M | $-39M | $-35M | $-33M | $-38M | $-27M | $-27M | $-26M | $-29M | $-22M | $-20M | $-23M | $-12M | $-12M | $-16M | |
| CapEx | $32.0K | $260.0K | $73.0K | $89.0K | $50.0K | $44.0K | $274.0K | $520.0K | $221.0K | $297.0K | $457.0K | $759.0K | $4M | $3M | $1M | $554.0K | |
| Investing Cash Flow | $78M | $2M | $50M | $36M | $-162M | $44M | $21M | $25M | $37M | $-268M | $23M | $3M | $49M | $-76M | $-26M | $-46.0K | |
| Stock Issued | · | · | $0 | $0 | · | · | $0 | $0 | $0 | $239M | · | · | · | $-555.0K | · | · | |
| Net Stock Activity | · | · | · | · | · | · | · | · | · | $239M | · | · | · | · | · | · | |
| Financing Cash Flow | $3M | $12M | $4M | $2M | $188M | $2M | $3M | $3M | $2M | $241M | $-211.0K | $369.0K | $21.0K | $-303.0K | $130M | $179.0K | |
| Net Change in Cash | $39M | $-28M | $15M | $3M | $-7M | $8M | $-3M | $1M | $13M | $-56M | $1M | $-16M | $26M | $-88M | $91M | $-16M | |
| Free Cash Flow | · | $-43M | · | · | · | · | · | · | · | $-29M | · | · | $-27M | · | · | · |
Redditività 2
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -10.5% | -10.1% | · | -7.4% | -6.3% | -8.1% | · | -8.3% | -7.3% | -6.3% | -7.5% | -7.3% | -7.4% | · | -5.2% | -5.7% | |
| ROE | -11.1% | -10.6% | · | -7.8% | -6.6% | -8.5% | · | -8.8% | -7.7% | -6.6% | -7.9% | -7.7% | -7.8% | · | -5.4% | -5.9% |
Liquidità e Solvibilità 3
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 16.2 | 22.6 | · | 26.5 | 28.9 | 21.0 | · | 26.3 | 30.2 | 37.1 | 18.2 | 22.0 | 26.2 | · | 27.8 | 27.5 | |
| Quick Ratio | 2.5 | 1.5 | · | 2.1 | 2.1 | 2.4 | · | 2.4 | 2.5 | 2.1 | 2.0 | 2.2 | 3.8 | · | 8.2 | 2.0 | |
| Debt / Equity | · | · | · | · | · | · | · | · | · | · | · | · | · | · | 0.0 | · |
Valutazione (TTM) 10
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q3 2022 | Q2 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-183M | $-167M | · | $-152M | $-143M | $-135M | · | $-120M | $-107M | $-99M | $-88M | $-78M | $-71M | · | $-61M | $-54M | |
| Market Cap | $4.38B | $3.39B | · | $1.72B | $1.38B | $2.09B | · | $2.52B | $1.69B | $1.70B | $364M | $492M | $422M | · | $622M | $396M | |
| Enterprise Value | · | · | · | · | · | · | · | · | · | · | · | · | · | · | $512M | · | |
| P/E | -23.6 | -19.4 | · | -10.7 | -8.9 | -15.1 | · | -18.5 | -12.7 | -12.7 | -4.0 | -5.7 | -5.1 | · | -8.1 | -7.3 | |
| P/B | 9.8 | 6.9 | · | 3.1 | 2.3 | 4.9 | · | 5.2 | 3.3 | 3.2 | 1.3 | 1.6 | 1.3 | · | 1.7 | 1.6 | |
| P / Tangible Book | 9.8 | 6.9 | · | 3.1 | 2.3 | 4.9 | · | 5.2 | 3.3 | 3.2 | 1.3 | 1.6 | 1.3 | · | 1.7 | 1.6 | |
| P / Cash Flow | · | -79.6 | · | · | · | -55.3 | · | · | · | -59.5 | · | · | -18.5 | · | · | · | |
| P / FCF | · | -79.1 | · | · | · | · | · | · | · | -58.9 | · | · | -15.5 | · | · | · | |
| EV / EBITDA | · | · | · | · | · | · | · | · | · | · | · | · | · | · | -28.0 | · | |
| Earnings Yield | -4.2% | -5.1% | · | -9.4% | -11.2% | -6.6% | · | -5.4% | -7.9% | -7.9% | -25.3% | -17.5% | -19.8% | · | -12.4% | -13.7% |
Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni
Conto Economico
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Utile netto | $-168M | $-134M | $-100M | $-68M | $-43M |
| EPS Diluito | $-1.63 | $-1.45 | $-1.57 | $-1.26 | $-1.14 |
Stato Patrimoniale
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Rapporto corrente | 19.9 | 19.9 | 19.5 | 21.5 | 27.0 |
| Quick Ratio | 2.2 | 1.7 | 5.1 | 1.3 | 1.5 |
Flusso di cassa
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | 2021-12-31 | |
|---|---|---|---|---|---|
| Flusso di cassa libero | $-144M | $-110M | $-98M | $-58M | $-34M |
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Proprietari istituzionali (13F) 249 filer · $4.0B totale · Aggiornato al 30 Giugno 2026
Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.
Attività istituzionale — Q2 2026 vs trimestre precedente
| Nuove posizioni | Posizioni chiuse | Aumentato | Diminuito | Variazione netta delle azioni |
|---|---|---|---|---|
| 47 (+1 vs trimestre precedente) | 24 (+1 vs trimestre precedente) | 79 (+12 vs trimestre precedente) | 74 (+9 vs trimestre precedente) | +3.3M |
Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.
| Istituzione | Valore | Azioni | % di 13F tracciati | Tipo |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | $630.516.330 | 15.518.492 | 15,63% | Azioni |
| Paradigm Biocapital Advisors LP | $415.053.937 | 10.215.455 | 10,29% | Azioni |
| RA CAPITAL MANAGEMENT, L.P. | $340.996.620 | 8.392.730 | 8,46% | Azioni |
| NOVO HOLDINGS A/S | $217.370.500 | 5.350.000 | 5,39% | Azioni |
| Driehaus Capital Management LLC | $192.123.952 | 4.728.623 | 4,76% | Azioni |
| PERCEPTIVE ADVISORS LLC | $177.714.564 | 4.373.974 | 4,41% | Azioni |
| VANGUARD CAPITAL MANAGEMENT LLC | $156.859.022 | 3.860.670 | 3,89% | Azioni |
| BAKER BROS. ADVISORS LP | $150.400.843 | 3.701.719 | 3,73% | Azioni |
| Siren, L.L.C. | $129.391.476 | 3.184.629 | 3,21% | Azioni |
| FMR LLC | $107.911.899 | 2.655.966 | 2,68% | Azioni |
| Cormorant Asset Management, LP | $101.981.300 | 2.510.000 | 2,53% | Azioni |
| Integral Health Asset Management, LLC | $81.260.000 | 2.000.000 | 2,01% | Azioni |
| BRAIDWELL LP | $81.136.688 | 1.996.965 | 2,01% | Azioni |
| GEODE CAPITAL MANAGEMENT, LLC | $77.257.283 | 1.901.081 | 1,92% | Azioni |
| STATE STREET CORP | $74.268.674 | 1.827.927 | 1,84% | Azioni |
| ALLIANCEBERNSTEIN L.P. | $66.749.256 | 2.119.024 | 1,66% | Azioni |
| MPM BIOIMPACT LLC | $65.852.291 | 1.620.780 | 1,63% | Azioni |
| MORGAN STANLEY | $65.647.597 | 1.615.742 | 1,63% | Azioni |
| BANK OF AMERICA CORP /DE/ | $56.886.145 | 1.400.102 | 1,41% | Azioni |
| Qube Research & Technologies Ltd | $50.889.359 | 1.252.507 | 1,26% | Azioni |
| AMERICAN CENTURY COMPANIES INC | $45.793.233 | 1.127.078 | 1,14% | Azioni |
| First Light Asset Management, LLC | $44.496.798 | 1.095.171 | 1,10% | Azioni |
| DIMENSIONAL FUND ADVISORS LP | $43.383.658 | 1.067.774 | 1,08% | Azioni |
| VICTORY CAPITAL MANAGEMENT INC | $36.683.608 | 902.870 | 0,91% | Azioni |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $31.953.707 | 786.456 | 0,79% | Azioni |
| Aberdeen Group plc | $26.325.233 | 647.926 | 0,65% | Azioni |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $25.212.215 | 620.532 | 0,63% | Azioni |
| Tyro Capital Management LLC | $24.904.768 | 612.965 | 0,62% | Azioni |
| Parkman Healthcare Partners LLC | $23.444.973 | 577.036 | 0,58% | Azioni |
| Artisan Partners Limited Partnership | $23.359.203 | 574.925 | 0,58% | Azioni |
| VANGUARD FIDUCIARY TRUST CO | $22.276.820 | 548.285 | 0,55% | Azioni |
| NORGES BANK | $20.726.988 | 510.140 | 0,51% | Azioni |
| Opaleye Management Inc. | $20.315.000 | 500.000 | 0,50% | Azioni |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $18.771.060 | 462.000 | 0,47% | Azioni |
| Soleus Capital Management, L.P. | $18.319.620 | 450.889 | 0,45% | Azioni |
| New Leaf Venture Partners, L.L.C. | $16.709.211 | 1.030.161 | 0,41% | Azioni |
| GOLDMAN SACHS GROUP INC | $15.838.224 | 389.816 | 0,39% | Azioni |
| Sofinnova Investments, Inc. | $15.476.901 | 380.923 | 0,38% | Azioni |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $13.570.989 | 334.014 | 0,34% | Azioni |
| CITADEL ADVISORS LLC | $13.539.054 | 333.228 | 0,34% | Azioni |
| Squadron Capital Management LLC | $11.782.700 | 290.000 | 0,29% | Azioni |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $11.511.820 | 283.333 | 0,29% | Azioni |
| DIADEMA PARTNERS LP | $11.060.055 | 272.214 | 0,27% | Azioni |
| KENNEDY CAPITAL MANAGEMENT LLC | $10.425.983 | 256.608 | 0,26% | Azioni |
| Schonfeld Strategic Advisors LLC | $10.368.855 | 255.202 | 0,26% | Azioni |
| DAFNA Capital Management LLC | $9.215.656 | 226.819 | 0,23% | Azioni |
| Woodline Partners LP | $9.112.903 | 224.290 | 0,23% | Azioni |
| PRUDENTIAL FINANCIAL INC | $9.053.380 | 222.825 | 0,22% | Azioni |
| PEREGRINE CAPITAL MANAGEMENT LLC | $8.067.899 | 198.570 | 0,20% | Azioni |
| SEB Asset Management AB | $7.884.765 | 194.063 | 0,20% | Azioni |
| Granahan Investment Management, LLC | $7.873.200 | 193.778 | 0,20% | Azioni |
| BARCLAYS PLC | $7.694.956 | 189.391 | 0,19% | Azioni |
| D. E. Shaw & Co., Inc. | $6.616.027 | 162.836 | 0,16% | Azioni |
| Caption Management, LLC | $6.480.485 | 159.500 | 0,16% | Opzione Call |
| ADAR1 Capital Management, LLC | $5.818.175 | 143.199 | 0,14% | Azioni |
| KVP Capital Advisors, LP | $5.403.790 | 133.000 | 0,13% | Azioni |
| NEUBERGER BERMAN GROUP LLC | $5.201.900 | 128.031 | 0,13% | Azioni |
| Point72 Asset Management, L.P. | $4.764.355 | 117.262 | 0,12% | Azioni |
| Quantum Private Wealth, LLC | $4.606.640 | 113.380 | 0,11% | Azioni |
| ALPS ADVISORS INC | $4.420.341 | 108.795 | 0,11% | Azioni |
| Moody Aldrich Partners LLC | $4.264.200 | 104.952 | 0,11% | Azioni |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | $4.063.000 | 100.000 | 0,10% | Opzione Put |
| Artia Global Partners LP | $4.014.244 | 98.800 | 0,10% | Azioni |
| Nuveen, LLC | $3.934.203 | 96.830 | 0,10% | Azioni |
| Swiss National Bank | $3.932.984 | 96.800 | 0,10% | Azioni |
| HighVista Strategies LLC | $3.697.168 | 90.996 | 0,09% | Azioni |
| BlackRock, Inc. | $3.668.036 | 90.279 | 0,09% | Azioni |
| RHUMBLINE ADVISERS | $3.666.114 | 90.232 | 0,09% | Azioni |
| JANUS HENDERSON GROUP PLC | $3.597.171 | 114.215 | 0,09% | Azioni |
| Ally Bridge Group (NY) LLC | $3.384.479 | 83.300 | 0,08% | Azioni |
| BOOTHBAY FUND MANAGEMENT, LLC | $3.361.482 | 82.734 | 0,08% | Azioni |
| NEW YORK STATE COMMON RETIREMENT FUND | $3.258.404 | 80.197 | 0,08% | Azioni |
| Centiva Capital, LP | $3.047.250 | 75.000 | 0,08% | Opzione Call |
| Jefferies Financial Group Inc. | $2.900.535 | 71.389 | 0,07% | Azioni |
| Persistent Asset Partners Ltd | $2.821.388 | 69.441 | 0,07% | Azioni |
| Bank of New York Mellon Corp | $2.805.298 | 69.045 | 0,07% | Azioni |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $2.638.000 | 64.918 | 0,07% | Azioni |
| TUDOR INVESTMENT CORP ET AL | $2.313.228 | 56.934 | 0,06% | Azioni |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | $2.312.699 | 73.419 | 0,06% | Azioni |
| STATE OF WISCONSIN INVESTMENT BOARD | $2.312.253 | 56.910 | 0,06% | Azioni |
| CITADEL ADVISORS LLC | $2.263.091 | 55.700 | 0,06% | Opzione Call |
| CITIGROUP INC | $2.252.324 | 55.435 | 0,06% | Azioni |
| HighMark Wealth Management LLC | $2.160.662 | 53.179 | 0,05% | Azioni |
| TWO SIGMA INVESTMENTS, LP | $2.013.135 | 49.548 | 0,05% | Azioni |
| ALGERT GLOBAL LLC | $1.919.361 | 47.240 | 0,05% | Azioni |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.913.673 | 47.100 | 0,05% | Opzione Put |
| XTX Topco Ltd | $1.862.154 | 45.832 | 0,05% | Azioni |
| BNP PARIBAS FINANCIAL MARKETS | $1.770.940 | 43.587 | 0,04% | Azioni |
| MetLife Investment Management, LLC | $1.698.497 | 41.804 | 0,04% | Azioni |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $1.655.957 | 40.757 | 0,04% | Azioni |
| Ensign Peak Advisors, Inc | $1.640.599 | 40.379 | 0,04% | Azioni |
| Knights of Columbus Asset Advisors LLC | $1.569.984 | 38.641 | 0,04% | Azioni |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1.568.318 | 38.600 | 0,04% | Opzione Call |
| Aquatic Capital Management LLC | $1.499.978 | 36.918 | 0,04% | Azioni |
| VANGUARD ASSET MANAGEMENT, Ltd | $1.452.279 | 35.744 | 0,04% | Azioni |
| Vanguard Global Advisers, LLC | $1.434.361 | 35.303 | 0,04% | Azioni |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $1.338.312 | 32.939 | 0,03% | Azioni |
| JANE STREET GROUP, LLC | $1.178.676 | 29.010 | 0,03% | Azioni |
| Invesco Ltd. | $1.158.077 | 28.503 | 0,03% | Azioni |
| Verdad Advisers, LP | $1.106.517 | 27.234 | 0,03% | Azioni |
Insider aziendali 15 insider · 0 dirigenti · 7 direttori
| Insider | Ruolo | Ultima attività | Azioni possedute | Acquisti 12m | Vendite 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Jonathan C Fox | Direttore | 01 Luglio 2026 A | 24.833 | 0 | 0 | $0 |
| Christopher Nathan Martin | Direttore | 05 Giugno 2026 A | — | 0 | 0 | $0 |
| Badreddin Edris | Direttore | 05 Giugno 2026 A | — | 0 | 0 | $0 |
| Laura Brege | Direttore | 05 Giugno 2026 A | — | 0 | 0 | $0 |
| Arlene Morris | Direttore | 05 Giugno 2026 A | — | 0 | 0 | $0 |
| Peter A. Thompson | Direttore | 05 Giugno 2026 A | 443.792 | 0 | 0 | $0 |
| Jonathan D Root | Direttore | 05 Giugno 2026 A | 0 | 0 | 0 | $0 |
| Novo Holdings A/S | Proprietario del 10% | 14 Settembre 2022 P | 6.071.703 | 0 | 0 | $0 |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | Proprietario del 10% | 30 Marzo 2021 C | 681.812 | 0 | 0 | $0 |
| Alan J Russell | — | 12 Agosto 2026 A | 31.466 | 0 | 5 | $-8.140.060 |
| Behrad Derakhshan | — | 12 Agosto 2026 A | 31.826 | 0 | 4 | $-223.420 |
| Michael Nofi | — | 12 Agosto 2026 A | — | 0 | 0 | $0 |
| Joanne M. Donovan | — | 12 Agosto 2026 A | 8.625 | 0 | 5 | $-412.712 |
| John R Moore | — | 12 Agosto 2026 A | 17.697 | 0 | 4 | $-219.831 |
| Kevin Koch | — | 12 Agosto 2026 A | 52.488 | 0 | 3 | $-785.049 |
Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato
Attivisti e proprietari del 5%+ 3 partecipazioni
Investitori che hanno depositato SEC Schedule 13D — proprietà effettiva superiore al 5% con l'intento di influenzare l'emittente (partecipazioni attiviste, campagne per il consiglio di amministrazione, M&A). Ogni riga mostra lo stato più recente noto della posizione di quel depositante.
| Depositante | Depositato | Partecipazione | Stato | Scopo | Deposito |
|---|---|---|---|---|---|
| Novo Holdings A/S ×7 depositi | 27 Aprile 2026 | 4,90% | Modifica | — | SEC |
| ORBIMED ADVISORS LLC, ORBIMED CAPITAL GP VI LLC, OrbiMed Genesis GP LLC, ORBIMED CAPITAL LLC ×5 depositi | 12 Maggio 2025 | 14,50% | Modifica | — | SEC |
| U.S. Venture Partners XI, L.P. (“USVP XI”), Presidio Management Group XI, L.L.C. (“PMG XI”), Casey M. Tansey, Jonathan D. Root ×2 depositi | 01 Febbraio 2023 | — | Deposito iniziale | — | SEC |
Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.
Proprietà ETF Posseduti da 45 ETF
Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.
| Fondo | Peso | Unità | Aggiornato al | Fonte |
|---|---|---|---|---|
| IBRN · iShares Trust | 3,54% | 6.153 SH | 08 Agosto 2026 | Giornaliero |
| SBIO · ALPS ETF Trust | 2,33% | 110.576 NS | 31 Maggio 2026 | N-PORT |
| PILL · Direxion Shares ETF Trust | 1,34% | 5.567 NS | 30 Aprile 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,97% | 11.685 NS | 30 Aprile 2026 | N-PORT |
| IHE · iShares Trust | 0,74% | 269.166 SH | 08 Agosto 2026 | Giornaliero |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,63% | 9.620 NS | 31 Maggio 2026 | N-PORT |
| DWAS · Invesco Exchange-Traded Fund Trust … | 0,47% | 48.340 SH | 08 Agosto 2026 | Giornaliero |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,32% | 5.857 SH | 08 Agosto 2026 | Giornaliero |
| IBB · iShares Trust | 0,27% | 577.144 SH | 08 Agosto 2026 | Giornaliero |
| IWO · iShares Trust | 0,20% | 647.964 SH | 08 Agosto 2026 | Giornaliero |
| BIB · ProShares Trust | 0,18% | 3.966 NS | 31 Maggio 2026 | N-PORT |
| VTWG · VANGUARD SCOTTSDALE FUNDS | 0,17% | 76.681 SH | 08 Agosto 2026 | Giornaliero |
| VFMO · VANGUARD WELLINGTON FUND | 0,13% | 65.171 SH | 08 Agosto 2026 | Giornaliero |
| BBSC · J.P. Morgan Exchange-Traded Fund Tr… | 0,13% | 30.264 NS | 30 Aprile 2026 | N-PORT |
| IWM · iShares Trust | 0,10% | 1.809.565 SH | 08 Agosto 2026 | Giornaliero |
| VTWO · VANGUARD SCOTTSDALE FUNDS | 0,09% | 411.642 SH | 08 Agosto 2026 | Giornaliero |
| ESML · iShares Trust | 0,06% | 42.227 SH | 08 Agosto 2026 | Giornaliero |
| RSSL · Global X Funds | 0,06% | 29.238 NS | 30 Aprile 2026 | N-PORT |
| ISCG · iShares Trust | 0,06% | 13.816 SH | 08 Agosto 2026 | Giornaliero |
| ISCB · iShares Trust | 0,06% | 3.892 SH | 08 Agosto 2026 | Giornaliero |
| ISCV · iShares Trust | 0,06% | 9.273 SH | 08 Agosto 2026 | Giornaliero |
| ITWO · ProShares Trust | 0,06% | 3.175 NS | 31 Maggio 2026 | N-PORT |
| SCHA · SCHWAB STRATEGIC TRUST | 0,05% | 355.389 NS | 31 Maggio 2026 | N-PORT |
| PRFZ · Invesco Exchange-Traded Fund Trust | 0,05% | 30.883 SH | 08 Agosto 2026 | Giornaliero |
| DFAS · Dimensional ETF Trust | 0,04% | 167.330 NS | 30 Aprile 2026 | N-PORT |
| UWM · ProShares Trust | 0,03% | 2.484 NS | 31 Maggio 2026 | N-PORT |
| VXF · VANGUARD INDEX FUNDS | 0,03% | 864.416 SH | 08 Agosto 2026 | Giornaliero |
| VHT · VANGUARD WORLD FUND | 0,03% | 145.298 SH | 08 Agosto 2026 | Giornaliero |
| FHLC · FIDELITY COVINGTON TRUST | 0,03% | 24.144 NS | 30 Aprile 2026 | N-PORT |
| URTY · ProShares Trust | 0,02% | 2.510 NS | 31 Maggio 2026 | N-PORT |
| WSML · iShares Trust | 0,02% | 3.101 SH | 08 Agosto 2026 | Giornaliero |
| MSSM · MORGAN STANLEY PATHWAY FUNDS | 0,01% | 2.733 NS | 31 Maggio 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 33.343 NS | 31 Maggio 2026 | N-PORT |
| VTI · VANGUARD INDEX FUNDS | 0,01% | 2.902.915 SH | 08 Agosto 2026 | Giornaliero |
| HDG · ProShares Trust | 0,01% | 63 NS | 31 Maggio 2026 | N-PORT |
| TILT · FlexShares Trust | 0,01% | 5.888 NS | 30 Aprile 2026 | N-PORT |
| AVSC · AMERICAN CENTURY ETF TRUST | 0,01% | 7.155 NS | 31 Maggio 2026 | N-PORT |
| DFAC · Dimensional ETF Trust | 0,01% | 105.864 NS | 30 Aprile 2026 | N-PORT |
| DCOR · Dimensional ETF Trust | 0,01% | 6.245 NS | 30 Aprile 2026 | N-PORT |
| ITOT · iShares Trust | 0,00% | 105.818 SH | 08 Agosto 2026 | Giornaliero |
| IWV · iShares Trust | 0,00% | 20.898 SH | 08 Agosto 2026 | Giornaliero |
| DFAU · Dimensional ETF Trust | 0,00% | 15.310 NS | 30 Aprile 2026 | N-PORT |
| SCHB · SCHWAB STRATEGIC TRUST | 0,00% | 44.236 NS | 31 Maggio 2026 | N-PORT |
| DFUS · Dimensional ETF Trust | 0,00% | 9.382 NS | 30 Aprile 2026 | N-PORT |
| VTHR · VANGUARD SCOTTSDALE FUNDS | 0,00% | 5.890 SH | 08 Agosto 2026 | Giornaliero |