GPCR Structure Therapeutics Inc. - American Depositary Shares
$53,70
Prezzo · Ago 19, 2026
Fondamentali al Ago 6, 2026
Intervallo 52 sett.
$18–$95
46% of range
Rating Analisti
BUY
23 analysts
Prezzo Obiettivo
$105
+96% upside
P/E (TTM)
-67.1
ROE
-12.3%
Margine di Profitto Netto
—
GPCR Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane
Prezzo
$53.70
Capitalizzazione di Mercato
$11.41B
P/E (TTM)
-67.1
EPS (TTM)
$-0.80
Ricavi (TTM)
—
Rendimento div.
—
ROE
-12.3%
D/E Debito/Patrimonio
—
Intervallo 52 sett.
$18 – $95
GPCR Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione
Configure
Performance decennale Andamento di ricavi, utile netto, margini e EPS
Ricavi e Utile Netto
—
EPS
$-0.80
2022-12-31
→
2025-12-31
Flusso di cassa libero
$-226M
2023-12-31
→
2025-12-31
Margini
—
Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?
Metrica
Tendenza 5 anni
GPCR
Mediana dei peer
P/E (TTM)
-67.1
38.7
P/B
7.5
3.8
Price / FCF (Prezzo / FCF)
-50.5
—
Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC
Metrica
Tendenza 5 anni
GPCR
Mediana dei peer
ROA
-11.3%
-6.4%
ROE
-12.3%
-16.8%
ROIC
-11.7%
—
Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio
Metrica
Tendenza 5 anni
GPCR
Mediana dei peer
Current Ratio (Rapporto corrente)
24.8
12.8
Quick Ratio
22.9
—
Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y
Metrica
Tendenza 5 anni
GPCR
Mediana dei peer
Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti
Metrica
Tendenza 5 anni
GPCR
Mediana dei peer
GPCR Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo
COMPRA
23 analisti
- Acquisto forte 8 34,8%
- Compra 13 56,5%
- Mantieni 2 8,7%
- Vendi 0 0,0%
- Vendita forte 0 0,0%
Target Price a 12 Mesi
15 analisti · 2026-08-14
Mediana
$104.00
← Sotto tutti i target
$53.70
Basso
$69.50
Alto
$145.00
Target mediano
$104.00
+93,7%
Target medio
$105.10
+95,7%
Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili
Sorpresa media
-0.49%
| Periodo | EPS Actual | EPS Stimato | Sorpresa |
|---|---|---|---|
| 30 Giugno 2026 | $-0.49 | $-0.41 | -0.08% |
| 31 Marzo 2026 | $-0.35 | $-0.35 | 0.00% |
| 31 Dicembre 2025 | $-1.22 | $-0.47 | -0.75% |
| 30 Settembre 2025 | $-1.11 | $-0.36 | -0.75% |
| 30 Giugno 2025 | $-1.08 | $-0.28 | -0.80% |
| 31 Marzo 2025 | $-0.81 | $-0.23 | -0.58% |
Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore
| Ticker | Capitalizzazione di Mercato | P/E | Rev YoY | Margine Netto | ROE | Margine lordo |
|---|---|---|---|---|---|---|
| GPCR | $14.78B | -86.9 | — | — | -12.3% | — |
| EWTX | $2.64B | -15.2 | — | — | -30.2% | — |
| MANE | — | — | — | — | 82.6% | — |
| INDV | — | 21.9 | 4.3% | 17.0% | -118.3% | 80.2% |
| ELVN | $915M | -8.4 | — | — | -21.9% | — |
| AMLX | $1.33B | -7.9 | -77.1% | — | -61.2% | — |
| OGN | $1.87B | 10.0 | -2.9% | 3.0% | 25.2% | 53.3% |
| MBX | $1.42B | -13.3 | — | — | -29.6% | — |
| ALMS | — | -3.4 | — | -1011.8% | -61.9% | — |
| TARS | $3.48B | -51.5 | 146.7% | -14.7% | -19.7% | — |
Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario
Conto Economico 12
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| R&D Expense | $225M | $109M | $70M | $36M | |
| SG&A Expense | $62M | $49M | $33M | $16M | |
| Operating Expenses | $177M | $158M | $103M | $53M | |
| Operating Income | $-177M | $-158M | $-103M | $-53M | |
| Pretax Income | $-141M | $-122M | $-89M | $-51M | |
| Income Tax | $515.0K | $310.0K | $236.0K | $17.0K | |
| Net Income | $-141M | $-123M | $-90M | $-51M | |
| EPS (Basic) | $-0.80 | $-0.78 | $-0.81 | $-5.51 | |
| EPS (Diluted) | $-0.80 | $-0.78 | $-0.81 | $-5.51 | |
| Shares (Basic) | 177,596,000 | 157,922,000 | 110,198,000 | 9,584,000 | |
| Shares (Diluted) | 177,596,000 | 157,922,000 | 110,198,000 | 9,584,000 | |
| EBITDA | $-177M | $-158M | $-103M | · |
Stato Patrimoniale 21
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Cash & Equivalents | $800M | $170M | $130M | $26M | |
| Short-term Investments | $647M | $714M | $338M | $65M | |
| Prepaid Expense | $24M | $8M | $6M | $2M | |
| Current Assets | $1.57B | $891M | $474M | $93M | |
| PP&E (Net) | $7M | $3M | $3M | $1M | |
| PP&E (Gross) | $10M | $5M | $4M | $1M | |
| Accum. Depreciation | $3M | $2M | $644.0K | $349.0K | |
| Other Non-current Assets | $717.0K | $5M | $45.0K | $3M | |
| Total Assets | $1.58B | $903M | $482M | $98M | |
| Accounts Payable | $14M | $8M | $5M | $6M | |
| Current Liabilities | $63M | $36M | $25M | $13M | |
| Capital Leases | $4M | $2M | $4M | · | |
| Other Non-current Liabilities | $647.0K | $302.0K | $298.0K | · | |
| Total Liabilities | $68M | $38M | $29M | $13M | |
| Common Stock | $21.0K | $17.0K | $14.0K | $1.0K | |
| Paid-in Capital | $1.99B | $1.19B | $659M | $2M | |
| Retained Earnings | $-470M | $-329M | $-207M | $-117M | |
| AOCI | $1M | $914.0K | $521.0K | $-110.0K | |
| Stockholders' Equity | $1.52B | $865M | $453M | $-115M | |
| Liabilities + Equity | $1.58B | $903M | $482M | $98M | |
| Shares Outstanding | 212,513,000 | 171,860,000 | 139,220,000 | 10,527,000 |
Flusso di cassa 10
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Stock-based Comp | $29M | $19M | $8M | $3M | |
| Operating Cash Flow | $-222M | $-117M | $-79M | $-46M | |
| CapEx | $4M | $1M | $2M | $155.0K | |
| Investing Cash Flow | $90M | $-359M | $-268M | $-62M | |
| Stock Issued | · | $515M | · | · | |
| Net Stock Activity | · | $515M | · | · | |
| Financing Cash Flow | $763M | $515M | $452M | $29M | |
| Net Change in Cash | $630M | $40M | $104M | $-79M | |
| Taxes Paid | $634.0K | $370.0K | $12.0K | · | |
| Free Cash Flow | $-226M | $-118M | $-82M | · |
Redditività 3
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| ROA | -11.3% | -17.7% | -30.9% | · | |
| ROE | -12.3% | -13.9% | -27.8% | · | |
| ROIC | -11.7% | -18.3% | -22.8% | · |
Liquidità e Solvibilità 2
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Current Ratio | 24.8 | 24.7 | 19.1 | · | |
| Quick Ratio | 22.9 | 24.5 | 18.9 | · |
Valutazione (TTM) 8
| Metrica | Tendenza | 2025 | 2024 | 2023 | 2022 |
|---|---|---|---|---|---|
| Net Income TTM | $-141M | $-123M | $-90M | $-51M | |
| Market Cap | $14.78B | $4.66B | $5.67B | · | |
| P/E | -86.9 | -34.8 | -50.3 | · | |
| P/B | 9.7 | 5.4 | 12.5 | · | |
| P / Tangible Book | 9.7 | 5.4 | 12.5 | · | |
| P / Cash Flow | -66.5 | -40.0 | -71.4 | · | |
| P / FCF | -65.5 | -39.5 | -69.5 | · | |
| Earnings Yield | -1.1% | -2.9% | -2.0% | · |
Conto Economico 12
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R&D Expense | $100M | $67M | $69M | $59M | $55M | $43M | $33M | $33M | $22M | $21M | $18M | $19M | $13M | $8M | $10M | $8M | |
| SG&A Expense | $19M | $23M | $18M | $15M | $16M | $13M | $14M | $13M | $11M | $11M | $9M | $7M | $7M | $5M | $4M | $4M | |
| Operating Expenses | $119M | $89M | $-24M | $74M | $70M | $56M | $47M | $46M | $33M | $32M | $26M | $26M | $20M | $13M | $14M | $13M | |
| Operating Income | $-119M | $-89M | $24M | $-74M | $-70M | $-56M | $-47M | $-46M | $-33M | $-32M | $-26M | $-26M | $-20M | $-13M | $-14M | $-13M | |
| Pretax Income | $-106M | $-76M | $33M | $-66M | $-62M | $-47M | $-36M | $-34M | $-26M | $-26M | $-23M | $-23M | $-18M | $-12M | $-14M | $-13M | |
| Income Tax | $234.0K | $190.0K | $170.0K | $108.0K | $139.0K | $98.0K | $136.0K | $92.0K | $53.0K | $29.0K | $405.0K | $118.0K | $25.0K | $-180.0K | $64.0K | $60.0K | |
| Net Income | $-106M | $-76M | $33M | $-66M | $-62M | $-47M | $-36M | $-34M | $-26M | $-26M | $-24M | $-23M | $-18M | $-12M | $-14M | $-13M | |
| EPS (Basic) | $-0.49 | $-0.35 | $0.20 | $-0.37 | $-0.36 | $-0.27 | $-0.21 | $-0.20 | $-0.18 | $-0.19 | $-0.21 | $-0.20 | $-0.25 | $-1.16 | $-1.64 | $-1.44 | |
| EPS (Diluted) | $-0.49 | $-0.35 | $0.20 | $-0.37 | $-0.36 | $-0.27 | $-0.21 | $-0.20 | $-0.18 | $-0.19 | $-0.21 | $-0.20 | $-0.25 | $-1.16 | $-1.64 | $-1.44 | |
| Shares (Basic) | 217,957,000 | 217,326,000 | -342,571,000 | 175,469,000 | 172,647,000 | 172,051,000 | -301,657,000 | 171,630,000 | 148,239,000 | 139,710,000 | 114,948,000 | 114,759,000 | 71,655,000 | -18,694,000 | 9,435,000 | 9,063,000 | |
| Shares (Diluted) | 217,957,000 | 217,326,000 | 4,194,000 | 175,469,000 | 172,647,000 | 172,051,000 | -301,657,000 | 171,630,000 | 148,239,000 | 139,710,000 | 114,948,000 | 114,759,000 | 71,655,000 | -18,694,000 | 9,435,000 | 9,063,000 | |
| EBITDA | $-119M | $-89M | · | $-74M | $-70M | $-56M | · | $-46M | $-33M | $-32M | $-26M | $-26M | $-20M | · | · | · |
Stato Patrimoniale 21
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash & Equivalents | $273M | $316M | $800M | $103M | $147M | $152M | $170M | $172M | $382M | $98M | $51M | $41M | $126M | $26M | · | · | |
| Short-term Investments | $1.07B | $1.14B | $647M | $696M | $639M | $685M | $714M | $743M | $545M | $339M | $155M | $184M | $114M | $65M | · | · | |
| Prepaid Expense | $29M | $32M | $24M | $15M | $13M | $13M | $8M | $8M | $11M | $13M | $5M | $4M | $5M | $2M | · | · | |
| Current Assets | $1.37B | $1.49B | $1.57B | $814M | $799M | $850M | $891M | $924M | $938M | $449M | $210M | $228M | $246M | $93M | · | · | |
| PP&E (Net) | $6M | $6M | $7M | $5M | $3M | $4M | $3M | $4M | $3M | $3M | $2M | $1M | $961.0K | $1M | · | · | |
| PP&E (Gross) | · | · | $10M | · | · | · | $5M | $5M | $4M | $4M | $3M | $2M | $1M | $1M | · | · | |
| Accum. Depreciation | · | · | $3M | · | · | · | $2M | $1M | $1M | $866.0K | $572.0K | $493.0K | $419.0K | $349.0K | · | · | |
| Other Non-current Assets | $41M | $6M | $717.0K | $7M | $6M | $6M | $5M | $2M | $2M | $47.0K | $350.0K | $38.0K | $59.0K | $3M | · | · | |
| Total Assets | $1.43B | $1.51B | $1.58B | $832M | $816M | $867M | $903M | $933M | $947M | $457M | $216M | $229M | $247M | $98M | · | · | |
| Accounts Payable | $11M | $8M | $14M | $18M | $9M | $9M | $8M | $8M | $2M | $7M | $3M | $6M | $5M | $6M | · | · | |
| Current Liabilities | $66M | $57M | $63M | $58M | $39M | $36M | $36M | $33M | $23M | $24M | $20M | $15M | $11M | $13M | · | · | |
| Capital Leases | $4M | $3M | $4M | $4M | $5M | $5M | $2M | $3M | $3M | $4M | $3M | · | · | · | · | · | |
| Other Non-current Liabilities | $1M | $863.0K | $647.0K | $325.0K | $317.0K | $308.0K | $302.0K | $309.0K | $293.0K | $296.0K | $281.0K | · | · | · | · | · | |
| Total Liabilities | $71M | $61M | $68M | $62M | $44M | $42M | $38M | $36M | $26M | $27M | $23M | $15M | $11M | $13M | · | · | |
| Common Stock | $21.0K | $21.0K | $21.0K | $18.0K | $17.0K | $17.0K | $17.0K | $17.0K | $17.0K | $14.0K | · | · | $11.0K | $1.0K | · | · | |
| Paid-in Capital | $2.01B | $2.00B | $1.99B | $1.27B | $1.21B | $1.20B | $1.19B | $1.19B | $1.18B | $663M | $375M | $373M | $371M | $2M | · | · | |
| Retained Earnings | $-652M | $-546M | $-470M | $-503M | $-438M | $-376M | $-329M | $-293M | $-259M | $-233M | $-182M | $-158M | $-135M | $-117M | · | · | |
| AOCI | $-3M | $-2M | $1M | $825.0K | $362.0K | $815.0K | $914.0K | $3M | $-487.0K | $-90.0K | $-310.0K | $-390.0K | $147.0K | $-110.0K | · | · | |
| Stockholders' Equity | $1.35B | $1.45B | $1.52B | $770M | $772M | $825M | $865M | $897M | $921M | $430M | $193M | $214M | $236M | $-115M | · | · | |
| Liabilities + Equity | $1.43B | $1.51B | $1.58B | $832M | $816M | $867M | $903M | $933M | $947M | $457M | $216M | $229M | $247M | $98M | · | · | |
| Shares Outstanding | 213,655,000 | 213,208,000 | 212,513,000 | 182,033,000 | 172,700,000 | 172,610,000 | 171,860,000 | 171,762,000 | 171,589,000 | 139,855,000 | · | · | 114,730,000 | 10,527,000 | · | · |
Flusso di cassa 8
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock-based Comp | $13M | $12M | $8M | $7M | $8M | $6M | $6M | $6M | $4M | $3M | $2M | $2M | $3M | $623.0K | $643.0K | $620.0K | |
| Operating Cash Flow | $-120M | $15M | $-64M | $-51M | $-55M | $-52M | $-36M | $-20M | $-26M | $-34M | $-21M | $-17M | $-20M | $-12M | $-10M | $-14M | |
| CapEx | $-42.0K | $1M | $1M | $2M | $232.0K | $314.0K | $16.0K | $685.0K | $427.0K | $162.0K | $820.0K | · | · | $71.0K | $-53.0K | $65.0K | |
| Investing Cash Flow | $74M | $-497M | $56M | $-49M | $49M | $34M | $33M | $-189M | $-205M | $1M | $30M | $-69M | $-49M | $10M | $-16M | $-40M | |
| Stock Issued | · | · | · | · | · | · | · | $0 | · | · | · | · | · | · | · | · | |
| Financing Cash Flow | $2M | $-2M | $705M | $56M | $517.0K | $809.0K | $615.0K | $-757.0K | $515M | $702.0K | $473.0K | $-297.0K | $170M | $-316.0K | $31M | $-1M | |
| Net Change in Cash | $-44M | $-483M | $697M | $-44M | $-5M | $-17M | $-3M | $-209M | $284M | $-32M | $10M | $-86M | $100M | $-2M | $5M | $-55M | |
| Free Cash Flow | · | $14M | · | · | · | $-53M | · | · | · | $-34M | · | · | · | · | · | · |
Redditività 3
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROA | -9.5% | -6.4% | · | -7.4% | -7.0% | -7.1% | · | -5.9% | -4.4% | -7.4% | -22.1% | · | -14.5% | · | · | · | |
| ROE | -10.0% | -6.7% | · | -7.9% | -7.3% | -7.5% | · | -6.2% | -4.6% | -7.8% | -24.7% | · | -15.2% | · | · | · | |
| ROIC | -8.8% | -6.2% | · | -9.6% | -9.2% | -6.8% | · | -5.1% | -3.6% | -7.5% | -13.8% | -12.2% | -8.3% | · | · | · |
Liquidità e Solvibilità 2
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 20.8 | 26.2 | · | 14.2 | 20.5 | 23.3 | · | 27.6 | 41.4 | 19.1 | 10.5 | 15.2 | 22.4 | · | · | · | |
| Quick Ratio | 20.3 | 25.6 | · | 13.9 | 20.1 | 22.9 | · | 27.4 | 40.9 | 18.5 | 10.2 | 15.0 | 21.9 | · | · | · |
Valutazione (TTM) 8
| Metrica | Tendenza | Q2 2026 | Q1 2026 | Q4 2025 | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 | Q3 2024 | Q2 2024 | Q1 2024 | Q3 2023 | Q2 2023 | Q1 2023 | Q4 2022 | Q2 2022 | Q1 2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Net Income TTM | $-310M | $-250M | · | $-208M | $-169M | $-133M | · | $-110M | $-99M | $-91M | $-78M | $-68M | $-57M | · | · | · | |
| Market Cap | $11.47B | $10.28B | · | $5.10B | $3.58B | $2.99B | · | $7.54B | $6.74B | $5.99B | · | · | $2.73B | · | · | · | |
| P/E | -34.2 | · | · | · | -24.7 | -20.6 | · | -56.3 | -50.3 | -50.4 | -26.1 | -12.4 | -5.2 | · | · | · | |
| P/B | 8.5 | 7.1 | · | 6.6 | 4.6 | 3.6 | · | 8.4 | 7.3 | 13.9 | · | · | 11.5 | · | · | · | |
| P / Tangible Book | 8.5 | 7.1 | · | 6.6 | 4.6 | 3.6 | · | 8.4 | 7.3 | 13.9 | · | · | 11.5 | · | · | · | |
| P / Cash Flow | · | 674.6 | · | · | · | -57.2 | · | · | · | -175.9 | · | · | -134.4 | · | · | · | |
| P / FCF | · | 731.3 | · | · | · | -56.9 | · | · | · | -175.1 | · | · | · | · | · | · | |
| Earnings Yield | -2.9% | · | · | · | -4.0% | -4.9% | · | -1.8% | -2.0% | -2.0% | -3.8% | -8.1% | -19.3% | · | · | · |
Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni
Conto Economico
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Utile netto | $-141M | $-123M | $-90M | $-51M |
| EPS Diluito | $-0.80 | $-0.78 | $-0.81 | $-5.51 |
Stato Patrimoniale
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Rapporto corrente | 24.8 | 24.7 | 19.1 | — |
| Quick Ratio | 22.9 | 24.5 | 18.9 | — |
Flusso di cassa
| 2025-12-31 | 2024-12-31 | 2023-12-31 | 2022-12-31 | |
|---|---|---|---|---|
| Flusso di cassa libero | $-226M | $-118M | $-82M | — |
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Proprietari istituzionali (13F) 206 filer · $2.9B totale · Aggiornato al 30 Giugno 2026
Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.
Attività istituzionale — Q2 2026 vs trimestre precedente
| Nuove posizioni | Posizioni chiuse | Aumentato | Diminuito | Variazione netta delle azioni |
|---|---|---|---|---|
| 32 (-8 vs trimestre precedente) | 28 (-10 vs trimestre precedente) | 71 (+3 vs trimestre precedente) | 58 (-9 vs trimestre precedente) | -489K |
Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.
| Istituzione | Valore | Azioni | % di 13F tracciati | Tipo |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | $351.836.637 | 6.555.555 | 12,00% | Azioni |
| FMR LLC | $345.296.142 | 6.433.690 | 11,78% | Azioni |
| WELLINGTON MANAGEMENT GROUP LLP | $340.675.263 | 6.347.592 | 11,62% | Azioni |
| Deep Track Capital, LP | $254.399.664 | 4.740.072 | 8,68% | Azioni |
| BVF INC/IL | $180.697.390 | 3.366.823 | 6,16% | Azioni |
| ORBIMED ADVISORS LLC | $118.578.498 | 2.209.400 | 4,05% | Azioni |
| PRINCIPAL FINANCIAL GROUP INC | $94.070.254 | 1.752.753 | 3,21% | Azioni |
| AMERICAN CENTURY COMPANIES INC | $90.282.956 | 1.682.179 | 3,08% | Azioni |
| RTW INVESTMENTS, LP | $86.274.901 | 1.607.507 | 2,94% | Azioni |
| Driehaus Capital Management LLC | $83.361.264 | 1.553.219 | 2,84% | Azioni |
| BAKER BROS. ADVISORS LP | $76.883.831 | 1.432.529 | 2,62% | Azioni |
| Casdin Capital, LLC | $63.062.250 | 1.175.000 | 2,15% | Azioni |
| DEERFIELD MANAGEMENT COMPANY, L.P. | $58.285.620 | 1.086.000 | 1,99% | Azioni |
| CAPITOLIS LIQUID GLOBAL MARKETS LLC | $55.875.837 | 1.041.100 | 1,91% | Azioni |
| Siren, L.L.C. | $46.852.139 | 872.967 | 1,60% | Azioni |
| Pacific Heights Asset Management LLC | $42.936.000 | 800.000 | 1,46% | Azioni |
| Rock Springs Capital Management LP | $34.365.813 | 640.317 | 1,17% | Azioni |
| Aberdeen Group plc | $34.344.238 | 639.915 | 1,17% | Azioni |
| ALLIANCEBERNSTEIN L.P. | $29.484.326 | 611.708 | 1,01% | Azioni |
| Logos Global Management LP | $26.835.000 | 500.000 | 0,92% | Azioni |
| Parkman Healthcare Partners LLC | $26.065.426 | 485.661 | 0,89% | Azioni |
| Davern Capital Partners, LP | $23.939.987 | 446.059 | 0,82% | Azioni |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | $22.476.996 | 418.800 | 0,77% | Azioni |
| DEUTSCHE BANK AG\ | $17.811.302 | 331.867 | 0,61% | Azioni |
| NEXTBio Capital Management LP | $16.771.660 | 312.496 | 0,57% | Azioni |
| Catalio Capital Management, LP | $14.842.438 | 276.550 | 0,51% | Azioni |
| MARSHALL WACE, LLP | $14.361.663 | 267.592 | 0,49% | Azioni |
| HSG Holding Ltd | $13.672.433 | 254.750 | 0,47% | Azioni |
| SEB Asset Management AB | $13.151.433 | 245.043 | 0,45% | Azioni |
| BANK OF AMERICA CORP /DE/ | $12.579.336 | 234.383 | 0,43% | Azioni |
| GOLDMAN SACHS GROUP INC | $12.520.889 | 233.294 | 0,43% | Azioni |
| NATIONAL BANK OF CANADA /FI/ | $11.581.986 | 215.800 | 0,40% | Azioni |
| TWO SIGMA INVESTMENTS, LP | $10.957.053 | 204.156 | 0,37% | Azioni |
| Eversept Partners, LP | $10.535.528 | 196.302 | 0,36% | Azioni |
| Schonfeld Strategic Advisors LLC | $10.234.062 | 190.685 | 0,35% | Azioni |
| Woodline Partners LP | $8.254.875 | 153.808 | 0,28% | Azioni |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $8.218.000 | 153.119 | 0,28% | Azioni |
| ArrowMark Colorado Holdings LLC | $8.081.575 | 150.579 | 0,28% | Azioni |
| Susquehanna Portfolio Strategies, LLC | $7.994.039 | 148.948 | 0,27% | Azioni |
| CenterBook Partners LP | $7.944.770 | 148.030 | 0,27% | Azioni |
| Rhenman & Partners Asset Management AB | $7.787.517 | 145.100 | 0,27% | Azioni |
| GOLDMAN SACHS GROUP INC | $7.782.150 | 145.000 | 0,27% | Opzione Call |
| B Group, Inc. | $7.513.800 | 140.000 | 0,26% | Azioni |
| HighVista Strategies LLC | $7.019.177 | 130.784 | 0,24% | Azioni |
| Universal- Beteiligungs- und Servicegesellschaft mbH | $6.745.728 | 125.689 | 0,23% | Azioni |
| Squarepoint Ops LLC | $6.739.610 | 125.575 | 0,23% | Azioni |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $6.566.202 | 122.344 | 0,22% | Azioni |
| D. E. Shaw & Co., Inc. | $6.188.151 | 115.300 | 0,21% | Azioni |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | $6.027.141 | 112.300 | 0,21% | Azioni |
| Soleus Capital Management, L.P. | $5.742.690 | 107.000 | 0,20% | Azioni |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $5.302.596 | 98.800 | 0,18% | Opzione Call |
| Avidity Partners Management LP | $5.259.660 | 98.000 | 0,18% | Azioni |
| GEODE CAPITAL MANAGEMENT, LLC | $5.215.811 | 97.183 | 0,18% | Azioni |
| Qube Research & Technologies Ltd | $5.012.939 | 93.403 | 0,17% | Azioni |
| PEREGRINE CAPITAL MANAGEMENT LLC | $4.949.930 | 92.229 | 0,17% | Azioni |
| PFM Health Sciences, LP | $4.913.489 | 91.550 | 0,17% | Azioni |
| PLATINUM INVESTMENT MANAGEMENT LTD | $4.849.782 | 90.363 | 0,17% | Azioni |
| MILLENNIUM MANAGEMENT LLC | $4.807.115 | 89.568 | 0,16% | Azioni |
| ExodusPoint Capital Management, LP | $4.200.536 | 78.266 | 0,14% | Azioni |
| Boxer Capital Management, LLC | $4.025.250 | 75.000 | 0,14% | Azioni |
| Cormorant Asset Management, LP | $4.025.250 | 75.000 | 0,14% | Azioni |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | $4.025.250 | 75.000 | 0,14% | Azioni |
| CITADEL ADVISORS LLC | $4.014.516 | 74.800 | 0,14% | Opzione Call |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3.869.607 | 72.100 | 0,13% | Opzione Put |
| ALPS ADVISORS INC | $3.855.277 | 71.833 | 0,13% | Azioni |
| TD Asset Management Inc | $3.701.191 | 68.962 | 0,13% | Azioni |
| Point72 Europe (London) LLP | $3.267.516 | 116.697 | 0,11% | Azioni |
| Brevan Howard Capital Management LP | $3.258.144 | 60.336 | 0,11% | Azioni |
| Burkehill Global Management, LP | $3.220.200 | 60.000 | 0,11% | Azioni |
| JANE STREET GROUP, LLC | $3.026.988 | 56.400 | 0,10% | Opzione Call |
| CITADEL ADVISORS LLC | $2.908.914 | 54.200 | 0,10% | Opzione Put |
| TUDOR INVESTMENT CORP ET AL | $2.879.718 | 53.656 | 0,10% | Azioni |
| ANTIPODES PARTNERS Ltd | $2.751.232 | 51.262 | 0,09% | Azioni |
| SCOGGIN MANAGEMENT LP | $2.683.500 | 50.000 | 0,09% | Opzione Call |
| Buckland Partners Management Co LLC | $2.683.500 | 50.000 | 0,09% | Azioni |
| SEVEN GRAND MANAGERS, LLC | $2.683.500 | 50.000 | 0,09% | Azioni |
| DAFNA Capital Management LLC | $2.495.655 | 46.500 | 0,09% | Azioni |
| Mariner, LLC | $2.484.116 | 46.285 | 0,08% | Azioni |
| STATE STREET CORP | $2.395.238 | 44.629 | 0,08% | Azioni |
| VOYA INVESTMENT MANAGEMENT LLC | $2.383.485 | 44.410 | 0,08% | Azioni |
| BANQUE PICTET & CIE SA | $2.325.628 | 43.332 | 0,08% | Azioni |
| Jump Financial, LLC | $2.289.455 | 42.658 | 0,08% | Azioni |
| Cinctive Capital Management LP | $2.193.869 | 40.877 | 0,07% | Azioni |
| Jefferies Financial Group Inc. | $2.180.344 | 40.625 | 0,07% | Azioni |
| Jones Hill Capital LP | $2.177.231 | 40.567 | 0,07% | Azioni |
| AMERIPRISE FINANCIAL INC | $2.117.656 | 39.457 | 0,07% | Azioni |
| OSAIC HOLDINGS, INC. | $2.115.279 | 39.414 | 0,07% | Azioni |
| STEMPOINT CAPITAL LP | $2.049.013 | 38.178 | 0,07% | Azioni |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | $2.045.256 | 38.108 | 0,07% | Azioni |
| CAPITAL FUND MANAGEMENT S.A. | $2.000.871 | 37.281 | 0,07% | Azioni |
| PSquared Asset Management AG | $1.996.524 | 37.200 | 0,07% | Azioni |
| FLAX POND CAPITAL, LLC | $1.932.120 | 36.000 | 0,07% | Azioni |
| TrueMark Investments, LLC | $1.803.312 | 33.600 | 0,06% | Azioni |
| NOMURA ASSET MANAGEMENT CO LTD | $1.759.839 | 32.790 | 0,06% | Azioni |
| DCF Advisers, LLC | $1.722.807 | 32.100 | 0,06% | Azioni |
| EXCHANGE TRADED CONCEPTS, LLC | $1.651.587 | 30.773 | 0,06% | Azioni |
| SPHERA FUNDS MANAGEMENT LTD. | $1.534.962 | 28.600 | 0,05% | Azioni |
| Verition Fund Management LLC | $1.530.615 | 28.519 | 0,05% | Azioni |
| Y-Intercept (Hong Kong) Ltd | $1.479.843 | 27.573 | 0,05% | Azioni |
| Seven Fleet Capital Management LP | $1.441.572 | 26.800 | 0,05% | Azioni |
Insider aziendali 15 insider · 4 dirigenti · 8 direttori
| Insider | Ruolo | Ultima attività | Azioni possedute | Acquisti 12m | Vendite 12m | Netto 12m |
|---|---|---|---|---|---|---|
| Raymond C Stevens | Chief Executive Officer | 07 Febbraio 2023 P | — | 0 | 0 | $0 |
| Jun Yoon | Chief Financial Officer | 07 Febbraio 2023 P | — | 0 | 0 | $0 |
| Mark Allen Bach | Chief Medical Officer | 07 Febbraio 2023 P | — | 0 | 0 | $0 |
| Melita Sun Jung | Chief Business Officer | 07 Febbraio 2023 P | — | 0 | 0 | $0 |
| Joanne Waldstreicher | Direttore | 17 Giugno 2026 A | — | 0 | 0 | $0 |
| Angus C. Russell | Direttore | 17 Giugno 2026 A | — | 0 | 0 | $0 |
| Sharon Tetlow | Direttore | 17 Giugno 2026 A | — | 0 | 0 | $0 |
| Daniel G Welch | Direttore | 17 Giugno 2026 A | 123.508 | 0 | 0 | $0 |
| Eric Dobmeier | Direttore | 17 Giugno 2026 A | — | 0 | 0 | $0 |
| Ted W Love | Direttore | 17 Giugno 2026 A | — | 0 | 0 | $0 |
| Ramy Farid | Direttore | 07 Febbraio 2023 P | 3.260.495 | 0 | 0 | $0 |
| FMR LLC | Proprietario del 10% | 22 Luglio 2026 S | 4.769.404 | 0 | 22 | $-7.057.088 |
| John Joseph Berrios | — | 06 Agosto 2026 A | 140.766 | 0 | 0 | $0 |
| Xichen Lin | — | 04 Agosto 2026 S | 228.960 | 0 | 5 | $-983.084 |
| FIL Ltd | — | 07 Febbraio 2023 C | 624.239 | 0 | 0 | $0 |
Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato
Proprietà ETF Posseduti da 14 ETF
Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.
| Fondo | Peso | Unità | Aggiornato al | Fonte |
|---|---|---|---|---|
| SBIO · ALPS ETF Trust | 1,78% | 73.020 NS | 31 Maggio 2026 | N-PORT |
| MID · AMERICAN CENTURY ETF TRUST | 0,70% | 17.825 NS | 31 Maggio 2026 | N-PORT |
| FDG · AMERICAN CENTURY ETF TRUST | 0,57% | 59.428 NS | 31 Maggio 2026 | N-PORT |
| BBC · ETFis Series Trust I | 0,46% | 4.115 NS | 30 Aprile 2026 | N-PORT |
| FMED · Fidelity Covington Trust | 0,44% | 4.628 NS | 31 Maggio 2026 | N-PORT |
| HRTS · Tema ETF Trust | 0,35% | 4.583 NS | 31 Maggio 2026 | N-PORT |
| IBBQ · Invesco Exchange-Traded Fund Trust … | 0,28% | 4.244 SH | 08 Agosto 2026 | Giornaliero |
| IBB · iShares Trust | 0,24% | 430.126 SH | 08 Agosto 2026 | Giornaliero |
| GDOC · Goldman Sachs ETF Trust | 0,20% | 1.008 NS | 31 Maggio 2026 | N-PORT |
| MMSC · First Trust Exchange-Traded Fund VI… | 0,19% | 2.531 NS | 31 Maggio 2026 | N-PORT |
| BIB · ProShares Trust | 0,15% | 2.880 NS | 31 Maggio 2026 | N-PORT |
| FFSM · FIDELITY COVINGTON TRUST | 0,13% | 40.344 NS | 30 Aprile 2026 | N-PORT |
| APIE · Trust for Professional Managers | 0,02% | 4.104 NS | 31 Maggio 2026 | N-PORT |
| ONEQ · Fidelity Commonwealth Trust | 0,01% | 20.734 NS | 31 Maggio 2026 | N-PORT |