INSM Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane

03

Prezzo $111.12

Capitalizzazione di Mercato (MRQ) $24.26B

P/E (TTM) -27.0

EPS (TTM) $-4.12

Ricavi (TTM) $1.14B

ROE (TTM) -87.2%

D/E Debito/Patrimonio (MRQ) 0.7

Intervallo 52 sett. $90–$213

INSM Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione

04

intervallo

barre

La granularità delle barre si adatta al periodo selezionato — passa il mouse sul grafico per vedere apertura/massimo/minimo/chiusura di una barra.

Split azionari 2

Data ex-dividendo	Split	Tipo
03 Marzo 2011	1-for-10	Inverso
31 Luglio 2000	1-for-4	Inverso

Performance decennale Andamento di ricavi, utile netto, margini e EPS

06

Ricavi$606M

2016-12-31 → 2025-12-31

EPS$-6.42

2019-12-31 → 2025-12-31

Flusso di cassa libero$-968M

2016-12-31 → 2025-12-31

Margine netto-76.9%

2018-12-31 → 2025-12-31

Valutazione e Rapporti 07–12

Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?

Metrica	INSM	media 5 anni	Mediana dei peer	Verdetto
P/E (TTM)	-27.0media 5 anni ≈-11.5	≈-11.5	·	·
P/S (TTM)	21.3media 5 anni ≈27.8	≈27.8	7.3	Sopravvalutato
P/B (MRQ)	32.0media 5 anni ≈23.7	≈23.7	6.1	Sopravvalutato
EV / EBITDA	-18.6media 5 anni ≈-12.9	≈-12.9	·	·
Prezzo / FCF (TTM)	-30.0media 5 anni ≈-16.0	≈-16.0	·	·
Prezzo / Flusso di cassa (TTM)	-31.1media 5 anni ≈-16.4	≈-16.4	·	·
EV / Ricavi (TTM)	20.8media 5 anni ≈27.3	≈27.3	·	·
EV / FCF (TTM)	-29.3media 5 anni ≈-15.7	≈-15.7	·	·
Prezzo / Valore contabile tangibile (MRQ)	36.5media 5 anni ≈75.5	≈75.5	·	·

La mediana dei peer viene calcolata su base standardizzata per metrica e potrebbe non corrispondere sempre alla base TTM/MRQ mostrata per questo titolo.

Redditività Margini lordi, operativi e netti; ROE, ROA, ROIC

Metrica	INSM	media 5 anni	Mediana dei peer	Verdetto
Margine Operativo (TTM)	-73.9%media 5 anni ≈-213.0%	≈-213.0%	16.9%	Debole
EBITDA Margin (Margine EBITDA)	-205.6%media 5 anni ≈-211.2%	≈-211.2%	15.8%	Debole
Margine ante imposte (TTM)	-76.4%media 5 anni ≈-226.4%	≈-226.4%	9.3%	Debole
Margine di Profitto Netto (TTM)	-76.9%media 5 anni ≈-226.9%	≈-226.9%	12.7%	Debole
ROA (TTM)	-38.2%media 5 anni ≈-48.0%	≈-48.0%	6.8%	Debole
ROE (TTM)	-87.2%media 5 anni ≈-376.1%	≈-376.1%	18.7%	Debole
ROIC	-97.8%media 5 anni ≈-64.8%	≈-64.8%	16.4%	Debole

Salute finanziaria Debito, liquidità, solvibilità — solidità del bilancio

Metrica	INSM	media 5 anni	Mediana dei peer	Verdetto
Debito / Patrimonio Netto (MRQ)	0.7media 5 anni ≈3.1	≈3.1	0.0	Debito elevato
Rapporto corrente (MRQ)	3.7media 5 anni ≈5.3	≈5.3	3.1	Liquidità elevata
Quick Ratio (MRQ)	3.1media 5 anni ≈4.7	≈4.7	1.7	Liquidità elevata
Debito a lungo termine / Patrimonio netto (MRQ)	0.7media 5 anni ≈3.1	≈3.1	·	·
Interest Coverage (Copertura degli interessi)	-14.9media 5 anni ≈-12.1	≈-12.1	-2.3	Bassa liquidità

Crescita Crescita di ricavi, EPS e utile netto: YoY, CAGR 3Y, CAGR 5Y

Metrica	INSM	media 5 anni	Mediana dei peer	Verdetto
Revenue YoY (Ricavi YoY)	66.7%media 5 anni ≈31.0%	≈31.0%	·	·
Revenue CAGR 3Y (CAGR Ricavi 3Y)	35.2%media 5 anni ≈27.5%	≈27.5%	·	·
Revenue CAGR 5Y (CAGR Ricavi 5Y)	29.8%	·	·	·

Metriche per Azione EPS, valore contabile per azione, flusso di cassa per azione, dividendo per azione

Metrica	INSM	media 5 anni	Mediana dei peer	Verdetto
EPS (Diluted) (EPS (Diluito))	$-6.42media 5 anni ≈$-5.02	≈$-5.02	·	·
Revenue / Share (Ricavi / Azione)	$3.05media 5 anni ≈$2.22	≈$2.22	·	·
Cash Flow / Share (Flusso di cassa / Azione)	$-4.70media 5 anni ≈$-3.84	≈$-3.84	·	·
Cash / Share (Liquidità / Azione)	$2.38media 5 anni ≈$4.54	≈$4.54	·	·

Efficienza del Capitale Rotazione delle attività, rotazione delle scorte, rotazione dei crediti

Metrica	INSM	media 5 anni	Mediana dei peer	Verdetto
Asset Turnover (Rotazione delle attività)	0.3media 5 anni ≈0.2	≈0.2	0.7	Debole
Inventory Turnover (Rotazione delle scorte)	1.1media 5 anni ≈0.9	≈0.9	1.9	Debole
Receivables Turnover (Rotazione dei crediti)	6.3media 5 anni ≈8.2	≈8.2	7.1	Debole
Revenue / Employee (Ricavi / Dipendente)	≈$364.4K	·	·	·

valore · ≈ media 5 anni · mediana del settore · giudizio rispetto alla mediana

Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili

14

Sorpresa media 6.1%

Prossimo report Ott 28, 2026

Periodo	Rapporto	EPS Actual	EPS Stimato	Sorpresa
30 Giugno 2026	Ago 5, 2026	$-0.06	$-0.80	92.5%
31 Marzo 2026	Mag 6, 2026	$-0.76	$-0.98	22.3%
31 Dicembre 2025		$-1.54	$-1.32	-17.0%
30 Settembre 2025		$-1.75	$-1.37	-28.1%
30 Giugno 2025		$-1.70	$-1.32	-28.9%
31 Marzo 2025		$-1.42	$-1.36	-4.5%

Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario

15

Conto Economico 17

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Revenue	$606M	$364M	$305M	$245M	$188M	$164M	$136M	$10M	$0	$0	$0	·
Cost of Revenue	$123M	$86M	$66M	$55M	$44M	$40M	$24M	$2M	$0	$0	·	·
Gross Profit	·	·	·	·	·	·	$112M	$7M	$0	·	·	·
R&D Expense	$771M	$598M	$571M	$398M	$273M	$181M	$132M	$145M	$110M	$123M	$74M	$56M
SG&A Expense	$701M	$461M	$345M	$266M	$234M	$204M	$211M	$168M	$79M	$51M	$43M	$31M
Operating Expenses	$1.85B	$1.24B	$1.01B	$703M	$564M	$430M	$372M	$317M	$189M	$173M	$117M	$87M
Operating Income	$-1.25B	$-878M	$-710M	$-457M	$-375M	$-265M	$-235M	$-307M	$-189M	$-173M	$-117M	$-87M
Interest Expense	$84M	$85M	$82M	$26M	$40M	$30M	$28M	$25M	$6M	$3M	$3M	$2M
Other Non-op	$-2M	$29.0K	$2M	$-6M	$-3M	$405.0K	$-531.0K	$602.0K	$300.0K	$119.0K	$-33.0K	$141.0K
Pretax Income	$-1.27B	$-910M	$-747M	$-480M	$-436M	$-293M	$-254M	$-324M	$-193M	$-176M	$-120M	$-90M
Income Tax	$5M	$4M	$3M	$1M	$-2M	$1M	$777.0K	$201.0K	$-272.0K	$98.0K	$-2M	$-10M
Net Income	$-1.28B	$-914M	$-750M	$-482M	$-435M	$-294M	$-254M	$-324M	$-193M	$-176M	$-118M	$-79M
EPS (Basic)	$-6.42	$-5.57	$-5.34	$-3.91	$-3.88	$-3.01	$-3.01	·	·	·	·	·
EPS (Diluted)	$-6.42	$-5.57	$-5.34	$-3.91	$-3.88	$-3.01	$-3.01	·	·	·	·	·
Shares (Basic)	199,014,000	164,043,000	140,433,000	123,035,000	112,111,000	97,605,000	84,560,000	76,889,000	66,576,000	61,892,000	58,633,000	43,095,000
Shares (Diluted)	199,014,000	164,043,000	140,433,000	123,035,000	112,111,000	97,605,000	84,560,000	76,889,000	66,576,000	61,892,000	58,633,000	43,095,000
EBITDA	$-1.25B	$-878M	$-704M	$-452M	$-366M	$-256M	$-230M	$-304M	$-186M	$-171M	$-116M	·

Stato Patrimoniale 27

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Cash & Equivalents	$510M	$555M	$482M	$1.07B	$717M	$533M	$487M	$495M	$381M	$163M	$283M	$159M
Short-term Investments	$920M	$879M	$298M	$74M	$0	·	·	·	·	·	·	·
Receivables	$141M	$52M	$41M	$30M	$24M	$17M	$19M	$6M	$0	·	·	·
Inventory	$132M	$99M	$83M	$70M	$67M	$50M	$28M	$7M	$0	·	·	·
Prepaid Expense	$91M	$37M	$24M	$25M	$29M	$24M	$20M	$11M	$8M	$6M	$5M	$5M
Current Assets	$1.79B	$1.62B	$929M	$1.27B	$837M	$623M	$555M	$519M	$389M	$168M	$288M	$165M
PP&E (Net)	$103M	$80M	$65M	$56M	$53M	$54M	$60M	$23M	$12M	$10M	$8M	$8M
PP&E (Gross)	$164M	$130M	$110M	$96M	$90M	$82M	$79M	$37M	$23M	$18M	$13M	$11M
Accum. Depreciation	$61M	$50M	$45M	$39M	$37M	$28M	$19M	$14M	$11M	$8M	$5M	$3M
Goodwill	$136M	$136M	$136M	$136M	$136M	$0	·	·	·	·	·	·
Intangibles	$98M	$59M	$64M	$69M	$74M	$49M	$54M	$59M	$58M	·	·	·
Total Assets	$2.26B	$2.03B	$1.33B	$1.66B	$1.24B	$796M	$742M	$605M	$462M	$238M	$357M	$231M
Accounts Payable	$80M	$73M	$65M	$50M	$36M	$43M	$13M	$18M	$15M	$10M	$7M	$9M
Accrued Liabilities	·	·	·	·	$61M	$38M	$40M	$38M	$17M	$17M	$11M	$10M
Current Liabilities	$469M	$298M	$226M	$190M	$135M	$119M	$85M	$80M	$45M	$28M	$22M	$20M
Capital Leases	$12M	$9M	$11M	$15M	$21M	$21M	$29M	·	·	·	·	·
Other Non-current Liabilities	$6M	$499.0K	$3M	$9M	$20M	$9M	$11M	$0	$765.0K	$693.0K	$572.0K	$23.0K
Total Liabilities	$1.53B	$1.74B	$1.66B	$1.57B	$833M	$520M	$481M	$396M	$101M	$83M	$45M	$45M
Long-term Debt	$547M	$1.12B	$1.18B	$1.15B	$800M	$450M	$450M	$450M	$55M	$55M	$25M	$25M
Total Debt	$541M	$1.10B	$1.16B	$1.13B	$567M	$356M	$336M	$317M	$56M	$55M	$25M	·
Common Stock	$2M	$2M	$1M	$1M	$1M	$1M	$897.0K	$773.0K	$766.0K	$620.0K	$618.0K	$498.0K
Paid-in Capital	$6.37B	$4.65B	$3.11B	$2.78B	$2.67B	$2.11B	$1.80B	$1.49B	$1.32B	$919M	$900M	$657M
Retained Earnings	$-5.64B	$-4.36B	$-3.45B	$-2.70B	$-2.27B	$-1.83B	$-1.54B	$-1.28B	$-958M	$-765M	$-589M	$-471M
AOCI	$1M	$-2M	$-745.0K	$756.0K	$968.0K	$193.0K	$-10.0K	$-9.0K	$-3.0K	$-65.0K	·	·
Stockholders' Equity	$739M	$285M	$-332M	$88M	$410M	$276M	$262M	$208M	$361M	$154M	$312M	$186M
Liabilities + Equity	$2.26B	$2.03B	$1.33B	$1.66B	$1.24B	$796M	$742M	$605M	$462M	$238M	$357M	$231M
Shares Outstanding	214,255,853	179,383,000	147,978,000	135,654,000	118,738,000	102,763,060	89,682,387	77,307,521	76,610,508	62,019,889	61,813,995	49,806,131

Flusso di cassa 15

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
D&A	·	·	$6M	$5M	$9M	$9M	$5M	$4M	$3M	$2M	$2M	$1M
Stock-based Comp	$153M	$97M	$75M	$58M	$46M	$36M	$27M	$26M	$18M	$18M	$16M	$11M
Deferred Tax	$-27.0K	$-29.0K	$-54.0K	$-231.0K	$-3M	$0	$0	$0	$-417.0K	$0	$0	·
Amort. of Intangibles	$6M	$5M	$5M	$5M	$5M	$5M	$5M	$1M	$0	$0	·	·
Other Non-cash	·	·	$133M	$18M	$20M	$29M	$-28M	$36M	$12M	$9M	$-89.0K	·
Operating Cash Flow	$-935M	$-684M	$-536M	$-400M	$-363M	$-219M	$-251M	$-258M	$-160M	$-147M	$-101M	$-64M
CapEx	$33M	$22M	$13M	$10M	$7M	$6M	$42M	$13M	$3M	$4M	$3M	$5M
Investing Cash Flow	$-65M	$-583M	$-224M	$-35M	$-64M	$-7M	$-42M	$-15M	$-3M	$-4M	$-3M	·
Stock Issued	$823M	$1.08B	$152M	$292M	$270M	$246M	$261M	$0	$378M	$0	$223M	$109M
Net Stock Activity	$823M	$1.08B	$152M	$292M	$270M	$246M	$261M	$0	$378M	·	$223M	·
Financing Cash Flow	$954M	$1.34B	$168M	$793M	$613M	$271M	$285M	$387M	$381M	$31M	$228M	·
Net Change in Cash	$-45M	$73M	$-592M	$357M	$184M	$45M	$-8M	$114M	$219M	$-120M	$124M	$45M
Taxes Paid	$4M	$2M	$2M	$2M	$2M	$814.0K	$339.0K	$154.0K	$166.0K	$85.0K	$-3M	$9M
Free Cash Flow	$-968M	$-706M	$-550M	$-410M	$-371M	$-226M	$-293M	$-271M	$-163M	$-151M	$-104M	·
Levered FCF	$-1.05B	$-791M	$-632M	$-437M	$-411M	$-255M	$-321M	$-297M	$-169M	$-154M	$-107M	·

Redditività 8

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Gross Margin	·	·	·	·	·	·	82.3%	·	·	·	·	·
Operating Margin	-205.6%	-241.5%	-232.5%	-186.4%	-199.0%	-161.3%	-172.4%	-3124.9%	·	·	·	·
Net Margin	-210.5%	-251.2%	-245.6%	-196.3%	-230.6%	-178.9%	-186.4%	-3297.2%	·	·	·	·
Pretax Margin	-209.7%	-250.2%	-244.8%	-195.7%	-231.6%	-178.0%	-185.8%	-3295.1%	·	·	·	·
EBITDA Margin	-205.6%	-241.5%	-230.7%	-184.2%	-194.2%	-155.8%	-168.6%	-3088.3%	·	·	·	·
ROA	-59.5%	-54.5%	-50.2%	-33.2%	-42.6%	-38.2%	-37.8%	-60.8%	-55.0%	-59.3%	-40.2%	·
ROE	-128.4%	-237.7%	241.3%	-1660.7%	-95.0%	-92.9%	-89.9%	-129.8%	-74.7%	-75.6%	-47.5%	·
ROIC	-97.8%	-63.5%	-86.5%	-37.8%	-38.2%	-42.1%	-39.5%	-58.6%	-45.3%	-82.9%	-34.3%	·

Liquidità e Solvibilità 5

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Current Ratio	3.8	5.5	4.1	6.7	6.2	5.2	6.5	6.5	8.7	6.0	12.9	·
Quick Ratio	3.4	5.0	3.6	6.2	5.5	4.6	5.9	6.3	8.5	5.8	12.7	·
Debt / Equity	0.7	3.9	-3.5	12.8	1.4	1.3	1.3	1.5	0.2	0.4	0.1	·
LT Debt / Equity	0.7	3.9	-3.5	12.8	1.4	1.3	1.3	1.5	0.2	0.4	0.1	·
Interest Coverage	-14.9	-10.3	-8.7	-17.3	-9.3	-9.0	-8.5	-12.1	-31.9	-49.6	-40.7	·

Efficienza 3

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Asset Turnover	0.3	0.2	0.2	0.2	0.2	0.2	0.2	0.0	0.0	·	·	·
Inventory Turnover	1.1	0.9	0.9	0.8	0.8	1.0	1.4	0.7	·	·	·	·
Receivables Turnover	6.3	7.8	8.6	9.1	9.2	9.2	11.0	3.6	·	·	·	·

Per Azione 5

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Book Value / Share	$3.45	$1.59	$-2.24	$0.65	$3.46	$2.68	$2.92	$2.69	$4.71	$2.49	$5.04	·
Revenue / Share	$3.05	$2.22	$2.17	$1.99	$1.68	$1.68	$1.61	$0.13	$0.00	·	·	·
Cash Flow / Share	$-4.70	$-4.17	$-3.82	$-3.25	$-3.24	$-2.25	$-2.96	$-3.36	$-2.40	$-2.37	$-1.72	·
Cash / Share	$2.38	$3.09	$3.26	$7.92	$6.04	$5.18	$5.44	$6.40	$4.98	$2.62	$4.58	·
EPS (TTM)	$-6.42	$-5.57	$-5.34	$-3.91	$-3.88	$-3.01	$-3.01	·	·	·	·	·

Tassi di Crescita 3

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Revenue YoY	66.7%	19.2%	24.4%	30.2%	14.6%	·	·	·	·	·	·	·
Revenue CAGR 3Y	35.2%	24.5%	22.9%	·	·	·	·	·	·	·	·	·
Revenue CAGR 5Y	29.8%	·	·	·	·	·	·	·	·	·	·	·

Valutazione (TTM) 14

Metrica	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014
Revenue TTM	$606M	$364M	$305M	$245M	$188M	$164M	$136M	$10M	$0	$0	$0	$12M
Net Income TTM	$-1.28B	$-914M	$-750M	$-482M	$-435M	$-294M	$-254M	$-324M	$-193M	$-176M	$-118M	$-79M
Market Cap	$37.29B	$12.38B	$4.59B	$2.71B	$3.23B	$3.42B	$2.14B	$1.01B	$2.39B	$821M	$1.12B	·
Enterprise Value	$36.40B	$12.05B	$4.96B	$2.69B	$3.08B	$3.24B	$1.99B	$836M	$2.06B	$713M	$864M	·
P/E	-27.1	-12.4	-5.8	-5.1	-7.0	-11.1	-7.9	·	·	·	·	·
P/S	61.5	34.1	15.0	11.0	17.2	20.8	15.7	103.1	·	·	·	·
P/B	50.5	43.4	-13.8	30.8	7.9	12.4	8.2	4.9	6.6	5.3	3.6	·
P / Tangible Book	73.8	136.7	·	·	16.1	15.1	·	·	·	·	·	·
P / Cash Flow	-39.9	-18.1	-8.6	-6.8	-8.9	-15.6	-8.5	-3.9	-15.0	-5.6	-11.1	·
P / FCF	-38.5	-17.5	-8.3	-6.6	-8.7	-15.2	-7.3	-3.7	-14.7	-5.4	-10.8	·
EV / EBITDA	-29.2	-13.7	-7.0	-5.9	-8.4	-12.7	-8.7	-2.8	-11.1	-4.2	-7.5	·
EV / FCF	-37.6	-17.1	-9.0	-6.5	-8.3	-14.4	-6.8	-3.1	-12.7	-4.7	-8.3	·
EV / Revenue	60.0	33.1	16.3	11.0	16.4	19.7	14.6	85.0	·	·	·	·
Earnings Yield	-3.7%	-8.1%	-17.2%	-19.6%	-14.2%	-9.0%	-12.6%	·	·	·	·	·

Conto Economico 16

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Revenue	$425M	$306M	$264M	$142M	$107M	$93M	$104M	$93M	$90M	$76M	$84M	$79M	$77M	$65M	$59M	$68M
Cost of Revenue	$67M	$47M	$44M	$29M	$28M	$21M	$26M	$21M	$21M	$17M	$18M	$17M	$17M	$14M	$13M	$13M
R&D Expense	$210M	$209M	$255M	$186M	$177M	$153M	$180M	$151M	$147M	$121M	$137M	$109M	$197M	$128M	$125M	$100M
SG&A Expense	$247M	$247M	$212M	$186M	$155M	$148M	$143M	$119M	$107M	$93M	$90M	$91M	$84M	$80M	$73M	$76M
Operating Expenses	$427M	$459M	$584M	$508M	$420M	$341M	$335M	$307M	$379M	$221M	$262M	$227M	$313M	$213M	$211M	$195M
Operating Income	$-2M	$-153M	$-320M	$-366M	$-313M	$-248M	$-230M	$-213M	$-289M	$-146M	$-178M	$-148M	$-236M	$-148M	$-151M	$-128M
Interest Expense	·	·	·	·	$21M	$22M	$22M	$21M	$21M	$21M	$21M	$20M	$21M	$20M	$16M	$3M
Other Non-op	$-531.0K	$-736.0K	$-2M	$-603.0K	$453.0K	$132.0K	$-445.0K	$2M	$-269.0K	$-1M	$2M	$285.0K	$-488.0K	$-111.0K	$1M	$-2M
Pretax Income	$-11M	$-162M	$-327M	$-369M	$-320M	$-256M	$-234M	$-220M	$-300M	$-157M	$-185M	$-158M	$-244M	$-159M	$-160M	$-131M
Income Tax	$2M	$1M	$2M	$1M	$1M	$912.0K	$1M	$1M	$838.0K	$589.0K	$998.0K	$544.0K	$530.0K	$483.0K	$125.0K	$372.0K
Net Income	$-13M	$-164M	$-328M	$-370M	$-322M	$-257M	$-236M	$-221M	$-301M	$-157M	$-186M	$-159M	$-245M	$-160M	$-160M	$-131M
EPS (Basic)	$-0.06	$-0.76	$-1.55	$-1.75	$-1.70	$-1.42	$-1.30	$-1.27	$-1.94	$-1.06	$-1.28	$-1.11	$-1.78	$-1.17	$-1.22	$-1.09
EPS (Diluted)	$-0.06	$-0.76	$-1.55	$-1.75	$-1.70	$-1.42	$-1.30	$-1.27	$-1.94	$-1.06	$-1.28	$-1.11	$-1.78	$-1.17	$-1.22	$-1.09
Shares (Basic)	217,352,000	215,468,000	·	211,759,000	189,302,000	180,860,000	·	173,721,000	154,702,000	148,456,000	·	142,899,000	137,553,000	136,355,000	·	120,789,000
Shares (Diluted)	217,352,000	215,468,000	·	211,759,000	189,302,000	180,860,000	·	173,721,000	154,702,000	148,456,000	·	142,899,000	137,553,000	136,355,000	·	120,789,000
EBITDA	$-2M	$-153M	·	$-366M	$-313M	$-248M	·	$-213M	$-289M	$-146M	·	$-148M	$-236M	$-148M	·	$-128M

Stato Patrimoniale 26

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Cash & Equivalents	$545M	$582M	$510M	$335M	$1.28B	$403M	$555M	$461M	$1.25B	$596M	·	$487M	$613M	$969M	·	$415M
Short-term Investments	$616M	$641M	$920M	$1.35B	$572M	$796M	$879M	$1.01B	$0	$0	·	$299M	$305M	$30M	·	$99M
Receivables	$215M	$179M	$141M	$65M	$55M	$48M	$52M	$42M	$40M	$37M	·	$36M	$31M	$31M	·	$27M
Inventory	$142M	$133M	$132M	$121M	$108M	$101M	$99M	$98M	$90M	$83M	·	$78M	$77M	$71M	·	$66M
Prepaid Expense	$116M	$78M	$91M	$66M	$62M	$55M	$37M	$41M	$41M	$43M	·	$27M	$26M	$29M	·	$25M
Current Assets	$1.63B	$1.61B	$1.79B	$1.93B	$2.08B	$1.40B	$1.62B	$1.65B	$1.42B	$759M	·	$927M	$1.05B	$1.13B	·	$632M
PP&E (Net)	$107M	$103M	$103M	$90M	$90M	$88M	$80M	$75M	$73M	$69M	·	$65M	$62M	$60M	·	$54M
PP&E (Gross)	$174M	$166M	$164M	$147M	$145M	$141M	$130M	$124M	$120M	$115M	·	$108M	$104M	$100M	·	$92M
Accum. Depreciation	$67M	$64M	$61M	$57M	$55M	$52M	$50M	$49M	$47M	$46M	·	$43M	$42M	$41M	·	$38M
Goodwill	$136M	$136M	$136M	$136M	$136M	$136M	$136M	$136M	$136M	$136M	·	$136M	$136M	$136M	·	$136M
Intangibles	$93M	$96M	$98M	$85M	$56M	$57M	$59M	$60M	$61M	$62M	$64M	$65M	$66M	$67M	·	$70M
Total Assets	$2.10B	$2.08B	$2.26B	$2.36B	$2.48B	$1.80B	$2.03B	$2.05B	$1.81B	$1.16B	·	$1.32B	$1.44B	$1.52B	·	$995M
Accounts Payable	$75M	$73M	$80M	$80M	$74M	$58M	$73M	$65M	$51M	$44M	·	$65M	$56M	$57M	·	$12M
Current Liabilities	$439M	$361M	$469M	$417M	$312M	$239M	$298M	$259M	$524M	$421M	·	$197M	$204M	$188M	·	$138M
Capital Leases	$8M	$10M	$12M	$8M	$8M	$8M	$9M	$10M	$12M	$14M	·	$13M	$13M	$15M	·	$17M
Other Non-current Liabilities	$6M	$6M	$6M	$6M	$6M	$5M	$499.0K	$3M	$3M	$3M	·	$6M	$11M	$10M	·	$11M
Total Liabilities	$1.35B	$1.37B	$1.53B	$1.42B	$1.23B	$1.70B	$1.74B	$1.57B	$1.77B	$1.62B	·	$1.61B	$1.59B	$1.56B	·	$1.02B
Long-term Debt	$547M	$547M	$547M	$547M	$547M	$1.12B	·	$972M	$1.19B	$1.18B	·	$1.17B	$1.17B	$1.16B	·	$800M
Total Debt	$544M	$542M	·	$540M	$539M	$1.11B	·	$955M	$1.17B	$1.16B	·	$1.15B	$1.14B	$1.13B	·	$785M
Common Stock	$2M	$2M	$2M	$2M	$2M	$2M	$2M	$2M	$2M	$1M	·	$1M	$1M	$1M	·	$1M
Paid-in Capital	$6.57B	$6.50B	$6.37B	$6.25B	$6.18B	$4.71B	$4.65B	$4.61B	$3.94B	$3.14B	·	$2.97B	$2.95B	$2.81B	·	$2.51B
Retained Earnings	$-5.81B	$-5.80B	$-5.64B	$-5.31B	$-4.94B	$-4.62B	$-4.36B	$-4.12B	$-3.90B	$-3.60B	·	$-3.26B	$-3.10B	$-2.86B	·	$-2.54B
AOCI	$-3M	$4.0K	$1M	$2M	$2M	$-902.0K	$-2M	$547.0K	$-3M	$-2M	·	$-2M	$-1M	$1M	·	$-1M
Stockholders' Equity	$757M	$705M	$739M	$946M	$1.25B	$99M	$285M	$483M	$39M	$-465M	$-332M	$-289M	$-156M	$-45M	$88M	$-30M
Liabilities + Equity	$2.10B	$2.08B	$2.26B	$2.36B	$2.48B	$1.80B	$2.03B	$2.05B	$1.81B	$1.16B	·	$1.32B	$1.44B	$1.52B	·	$995M
Shares Outstanding	218,281,059	216,521,841	214,255,853	212,583,015	211,110,658	181,900,074	179,382,635	178,846,991	166,666,599	148,560,882	147,978,000	143,049,197	142,750,463	136,429,216	135,654,000	121,726,199

Flusso di cassa 12

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Stock-based Comp	$41M	$46M	$39M	$31M	$43M	$39M	$27M	$26M	$23M	$21M	$20M	$20M	$18M	$16M	$15M	$16M
Deferred Tax	$0	$0	$-27.0K	$0	$0	$0	$-29.0K	$0	$0	$0	$-54.0K	$0	$0	$0	$-231.0K	$0
Amort. of Intangibles	$2M	$2M	$2M	$2M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M	$1M
Operating Cash Flow	$-89M	$-223M	$-248M	$-220M	$-206M	$-262M	$-196M	$-181M	$-123M	$-184M	$-131M	$-136M	$-123M	$-146M	$-103M	$-90M
CapEx	$6M	$3M	$17M	$2M	$3M	$10M	$7M	$4M	$7M	$5M	$2M	$3M	$5M	$3M	$5M	$582.0K
Investing Cash Flow	$25M	$266M	$389M	$-762M	$228M	$80M	$132M	$-1.00B	$-7M	$295M	$2M	$7M	$-274M	$42M	$20M	$49M
Stock Issued	·	·	$0	$-256.0K	·	·	$-12.0K	$371M	·	·	$114M	$0	·	·	$259M	$33M
Financing Cash Flow	$27M	$30M	$34M	$33M	$858M	$29M	$159M	$397M	$781M	$3M	$123M	$1M	$44M	$-399.0K	$743M	$37M
Net Change in Cash	$-37M	$72M	$176M	$-950M	$881M	$-152M	$94M	$-785M	$651M	$113M	$-5M	$-126M	$-356M	$-105M	$659M	$-1M
Taxes Paid	$696.0K	$3M	$111.0K	$1M	$677.0K	$2M	$248.0K	$689.0K	$354.0K	$1M	$75.0K	$518.0K	$358.0K	$1M	$91.0K	$432.0K
Free Cash Flow	·	$-226M	·	·	·	$-272M	·	·	·	$-189M	·	·	·	$-150M	·	·
Levered FCF	·	·	·	·	·	$-294M	·	·	·	$-210M	·	·	·	$-170M	·	·

Redditività 7

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Operating Margin	-0.36%	-50.1%	·	-257.1%	-291.3%	-267.3%	·	-228.4%	-319.8%	-192.7%	·	-186.8%	-305.0%	-227.2%	·	-188.5%
Net Margin	-3.1%	-53.5%	·	-259.9%	-299.5%	-276.4%	·	-236.0%	-332.8%	-208.1%	·	-201.0%	-317.0%	-245.0%	·	-193.6%
Pretax Margin	-2.7%	-53.0%	·	-259.0%	-298.3%	-275.4%	·	-235.0%	-331.8%	-207.3%	·	-200.3%	-316.3%	-244.2%	·	-193.1%
EBITDA Margin	-0.36%	-50.1%	·	-257.1%	-291.3%	-267.3%	·	-228.4%	-319.8%	-192.7%	·	-186.8%	-305.0%	-227.2%	·	-188.5%
ROA	-0.58%	-8.4%	·	-16.8%	-15.0%	-17.3%	·	-13.1%	-18.5%	-11.7%	·	-13.7%	-19.6%	-12.0%	·	-11.4%
ROE	-1.3%	-40.7%	·	-51.8%	-49.9%	140.3%	·	-227.3%	514.2%	61.7%	·	99.6%	439.1%	-424.7%	·	-55.2%
ROIC	-0.14%	-12.4%	·	-24.7%	-17.6%	-20.7%	·	-14.9%	-23.9%	-20.9%	·	-17.3%	-24.0%	-13.7%	·	-17.0%

Liquidità e Solvibilità 5

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Current Ratio	3.7	4.5	·	4.6	6.7	5.9	·	6.4	2.7	1.8	·	4.7	5.2	6.0	·	4.6
Quick Ratio	3.1	3.9	·	4.2	6.1	5.2	·	5.8	2.5	1.5	·	4.2	4.6	5.5	·	3.9
Debt / Equity	0.7	0.8	·	0.6	0.4	11.1	·	2.0	30.2	-2.5	·	-4.0	-7.3	-25.4	·	-26.2
LT Debt / Equity	0.7	0.8	·	0.6	0.4	11.1	·	2.0	24.4	-2.0	·	-4.0	-7.3	-25.4	·	-26.2
Interest Coverage	·	·	·	·	-14.7	-11.5	·	-10.1	-13.6	-6.9	·	-7.3	-11.4	-7.4	·	-38.1

Efficienza 3

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Asset Turnover	0.2	0.2	·	0.1	0.1	0.1	·	0.1	0.1	0.1	·	0.1	0.1	0.0	·	0.1
Inventory Turnover	0.5	0.4	·	0.3	0.3	0.2	·	0.2	0.3	0.2	·	0.2	0.2	0.2	·	0.2
Receivables Turnover	3.1	2.7	·	2.6	2.3	2.2	·	2.4	2.5	2.2	·	2.5	2.6	2.3	·	2.9

Per Azione 5

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Book Value / Share	$3.47	$3.26	·	$4.45	$5.92	$0.55	·	$2.70	$0.23	$-3.13	·	$-2.02	$-1.09	$-0.33	·	$-0.25
Revenue / Share	$1.96	$1.42	·	$0.67	$0.57	$0.51	·	$0.54	$0.58	$0.51	·	$0.55	$0.56	$0.48	·	$0.56
Cash Flow / Share	·	$-1.03	·	·	·	$-1.45	·	·	·	$-1.24	·	·	·	$-1.07	·	·
Cash / Share	$2.50	$2.69	·	$1.57	$6.08	$2.22	·	$2.58	$7.48	$4.01	·	$3.41	$4.29	$7.10	·	$3.41
EPS (TTM)	$-4.12	$-5.76	·	$-6.17	$-5.69	$-5.93	·	$-5.55	$-5.39	$-5.23	·	$-5.28	$-5.26	$-4.28	·	$-3.65

Valutazione (TTM) 11

Metrica	Q2 2026	Q1 2026	Q4 2025	Q3 2025	Q2 2025	Q1 2025	Q4 2024	Q3 2024	Q2 2024	Q1 2024	Q4 2023	Q3 2023	Q2 2023	Q1 2023	Q4 2022	Q3 2022
Revenue TTM	$1.14B	$820M	·	$447M	$398M	$381M	·	$343M	$329M	$315M	·	$281M	$269M	$257M	·	$242M
Net Income TTM	$-875M	$-1.18B	·	$-1.18B	$-1.03B	$-1.01B	·	$-864M	$-803M	$-747M	·	$-724M	$-696M	$-547M	·	$-434M
Market Cap	$23.27B	$35.41B	·	$30.61B	$21.25B	$13.88B	·	$13.06B	$11.17B	$4.03B	·	$3.61B	$3.01B	$2.33B	·	$2.62B
Enterprise Value	$22.66B	$34.72B	·	$29.47B	$19.93B	$13.78B	·	$12.54B	$11.09B	$4.60B	·	$3.97B	$3.23B	$2.46B	·	$2.89B
P/E	-25.9	-28.4	·	-23.3	-17.7	-12.9	·	-13.2	-12.4	-5.2	·	-4.8	-4.0	-4.0	·	-5.9
P/S	20.5	43.2	·	68.5	53.4	36.4	·	38.1	34.0	12.8	·	12.9	11.2	9.0	·	10.8
P/B	30.7	50.2	·	32.4	17.0	139.9	·	27.0	287.7	-8.7	·	-12.5	-19.3	-52.1	·	-87.5
P / Tangible Book	44.1	74.8	·	42.2	20.1	·	·	45.4	·	·	·	·	·	·	·	·
P / Cash Flow	·	-159.0	·	·	·	-52.9	·	·	·	-21.9	·	·	·	-15.9	·	·
EV / Revenue	19.9	42.4	·	65.9	50.1	36.2	·	36.6	33.8	14.6	·	14.2	12.0	9.6	·	11.9
Earnings Yield	-3.9%	-3.5%	·	-4.3%	-5.7%	-7.8%	·	-7.6%	-8.0%	-19.3%	·	-20.9%	-24.9%	-25.1%	·	-17.0%

Periodo più recente a sinistra · valori nulli mostrati come ·

Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni

16

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Ricavi	$606M	$364M	$305M	$245M	$188M
Margine Operativo %	-205.6%	-241.5%	-232.5%	-186.4%	-199.0%
Utile netto	$-1.28B	$-914M	$-750M	$-482M	$-435M
EPS Diluito	$-6.42	$-5.57	$-5.34	$-3.91	$-3.88

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Debito / Patrimonio Netto	0.7	3.9	-3.5	12.8	1.4
Rapporto corrente	3.8	5.5	4.1	6.7	6.2
Quick Ratio	3.4	5.0	3.6	6.2	5.5

Metrica	2025-12-31	2024-12-31	2023-12-31	2022-12-31	2021-12-31
Flusso di cassa libero	$-968M	$-706M	$-550M	$-410M	$-371M

Proprietari istituzionali (13F) 747 filer · $27.2B totale · Aggiornato al 30 Settembre 2026

17

Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.

Detentori 747

Valore detenuto $27.2B

Nuove posizioni 129

Posizioni chiuse 115

Attività istituzionale — Q2 2026 vs trimestre precedente

Nuove posizioni	Posizioni chiuse	Aumentato	Diminuito	Variazione netta delle azioni
129 (+11 vs trimestre precedente)	115 (+23 vs trimestre precedente)	256 (-28 vs trimestre precedente)	241 (+13 vs trimestre precedente)	+7.8M

Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.

Istituzione	Valore	Azioni	% di 13F tracciati	Tipo
VANGUARD GROUP INC	$3.668.126.910	21.076.344	13,48%	Azioni
FMR LLC	$1.721.228.828	16.143.583	6,33%	Azioni
BlackRock, Inc.	$1.685.447.191	15.807.984	6,19%	Azioni
VANGUARD PORTFOLIO MANAGEMENT LLC	$1.109.696.908	10.407.962	4,08%	Azioni
JPMORGAN CHASE & CO	$1.092.246.620	10.428.170	4,01%	Azioni
VANGUARD CAPITAL MANAGEMENT LLC	$1.043.902.026	9.790.865	3,84%	Azioni
BAKER BROS. ADVISORS LP	$937.841.355	8.796.111	3,45%	Azioni
Capital International Investors	$878.338.960	8.238.124	3,23%	Azioni
Darwin Global Management, Ltd.	$673.600.013	6.431.163	2,48%	Azioni
AMERIPRISE FINANCIAL INC	$658.878.001	6.179.571	2,42%	Azioni
Orbis Allan Gray Ltd	$647.875.044	6.076.487	2,38%	Azioni
STATE STREET CORP	$645.282.792	6.052.174	2,37%	Azioni
D. E. Shaw & Co., Inc.	$626.707.989	5.877.959	2,30%	Azioni
Artisan Partners Limited Partnership	$580.195.955	5.441.718	2,13%	Azioni
RTW INVESTMENTS, LP	$516.347.866	4.842.880	1,90%	Azioni
GEODE CAPITAL MANAGEMENT, LLC	$448.763.113	4.220.155	1,65%	Azioni
NORGES BANK	$360.124.083	3.377.641	1,32%	Azioni
UBS Group AG	$275.553.633	2.584.446	1,01%	Azioni
CITADEL ADVISORS LLC	$272.624.461	2.556.973	1,00%	Azioni
FRANKLIN RESOURCES INC	$242.371.000	2.273.222	0,89%	Azioni
MAVERICK CAPITAL LTD	$229.314.244	2.150.762	0,84%	Azioni
MILLENNIUM MANAGEMENT LLC	$218.358.293	2.048.005	0,80%	Azioni
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	$198.680.888	1.215.025	0,73%	Azioni
Qube Research & Technologies Ltd	$179.370.451	1.682.334	0,66%	Azioni
WESTFIELD CAPITAL MANAGEMENT CO LP	$173.743.795	1.629.561	0,64%	Azioni
Integral Health Asset Management, LLC	$170.592.000	1.600.000	0,63%	Azioni
GOLDMAN SACHS GROUP INC	$150.322.007	1.409.885	0,55%	Azioni
VANGUARD FIDUCIARY TRUST CO	$149.433.474	1.401.552	0,55%	Azioni
Bellevue Group AG	$148.566.227	1.393.418	0,55%	Azioni
Balyasny Asset Management L.P.	$141.423.967	1.326.430	0,52%	Azioni
Paradigm Biocapital Advisors LP	$141.375.668	1.325.977	0,52%	Azioni
NORTHERN TRUST CORP	$140.239.951	1.315.325	0,52%	Azioni
Bank of New York Mellon Corp	$139.965.961	1.312.756	0,51%	Azioni
TWO SIGMA INVESTMENTS, LP	$132.445.710	1.242.222	0,49%	Azioni
MORGAN STANLEY	$131.515.791	1.233.498	0,48%	Azioni
Pictet Asset Management Holding SA	$129.804.038	1.220.353	0,48%	Azioni
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	$129.432.735	1.213.963	0,48%	Azioni
Hood River Capital Management LLC	$112.683.586	1.056.871	0,41%	Azioni
BANK OF AMERICA CORP /DE/	$109.084.466	1.023.114	0,40%	Azioni
SEI INVESTMENTS CO	$108.312.723	1.015.870	0,40%	Azioni
Castle Hook Partners LP	$105.906.712	993.310	0,39%	Azioni
JENNISON ASSOCIATES LLC	$96.501.143	905.094	0,35%	Azioni
TimesSquare Capital Management, LLC	$95.626.169	584.798	0,35%	Azioni
Polar Capital Holdings Plc	$94.984.773	890.872	0,35%	Azioni
MILLENNIUM MANAGEMENT LLC	$92.119.680	864.000	0,34%	Opzione Call
FIL Ltd	$91.289.537	856.214	0,34%	Azioni
PRINCIPAL FINANCIAL GROUP INC	$91.280.154	856.126	0,34%	Azioni
ADAGE CAPITAL PARTNERS GP, L.L.C.	$90.627.000	850.000	0,33%	Azioni
Fiera Capital Corp	$89.885.138	843.042	0,33%	Azioni
Legal & General Group Plc	$88.114.072	826.431	0,32%	Azioni

Mostra tutti i 747 proprietari istituzionali →

Insider aziendali 48 insider · 31 dirigenti · 18 direttori

19

Insider	Ruolo	Ultima attività	Azioni possedute	Vendite 12m	Netto 12m
William Lewis	Chair and CEO	23 Luglio 2026 M	259.058	74	$-32.791.057
Timothy Whitten	President & CEO	01 Giugno 2012 P	10.000	0	$0
Geoffrey Allan	President, CEO and Chairman	31 Marzo 2009 M	1.715.557	0	$0
Sara Bonstein	Chief Financial Officer	03 Giugno 2026 S	69.082	6	$-2.132.573
Paolo Tombesi	Chief Financial Officer	03 Gennaio 2019 A	10.669	0	$0
Andrew T Drechsler	Chief Financial Officer	01 Marzo 2017 M	15.000	0	$0
Kevin P Tully	Executive VP & CFO	21 Dicembre 2011 A	377.344	0	$0
Steve C Glover	President Follow-on Biologics	31 Marzo 2009 M	372.113	0	$0
Roger Adsett	Chief Operating Officer	10 Agosto 2026 M	98.744	10	$-48.253.225
Ronald D Gunn	Executive Vice President & COO	08 Dicembre 2005 A	40.074	0	$0
Martina Flammer M.D.	Chief Medical Officer	06 Agosto 2026 M	60.486	40	$-23.323.179
Samuele Butera	SVP, GM, Global Respiratory	23 Giugno 2026 A	7.342	0	$0
Michael Alexander Smith	Chief Legal Officer	22 Giugno 2026 S	37.648	20	$-13.997.738
Orlov S Nicole Schaeffer	Chief People Strategy Officer	02 Gennaio 2026 M	41.754	9	$-21.113.483
John Drayton Wise	Chief Commercial Officer	07 Febbraio 2025 S	133.015	0	$0
John Soriano	Chief Compliance Officer	07 Settembre 2021 M	35.204	0	$0
Christine A Pellizzari	Chief Legal Officer	15 Maggio 2021 F	149.985	0	$0
John Goll	Chief Accounting Officer	03 Gennaio 2020 A	14.166	0	$0
Paul Streck	Chief Medical Officer	08 Agosto 2018 A	15.996	0	$0
Eugene Jeffrey Sullivan	Chief Med. & Scientific Ofc.	17 Maggio 2017 A	·	0	$0
Mark Quigley	Vice President, Quality	12 Maggio 2015 M	0	0	$0
Peggy Berry	Vice President, Regulatory	26 Febbraio 2015 A	·	0	$0
Matthew Pauls	Chief Commercial Officer	02 Giugno 2014 A	·	0	$0
Renu Gupta	Executive Vice President & CMO	31 Gennaio 2014 M	37.014	0	$0
Andrea Holtzman Drucker	SVP, Gen. Counsel & Corp Sec.	03 Giugno 2013 M	45.000	0	$0
Nicholas A. Labella Jr.	Chief Scientific Officer	21 Dicembre 2011 A	·	0	$0
Nicholas Lee Gurreri	Senior VP, Commercial Ops	31 Gennaio 2011 A	·	0	$0
Doug Farrar	Vice President, ITP	31 Marzo 2009 M	292.055	0	$0
Michael Duncan	Principal Financial Officer	08 Dicembre 2005 A	·	0	$0
Philip J Young	Chief Business Officer and EVP	08 Dicembre 2005 A	·	0	$0
Thomas A Keuer	Sr VP, ITP (Subsidiary)	08 Dicembre 2005 A	·	0	$0
David R Brennan	Direttore	09 Settembre 2026 S	39.238	1	$-3.100.000
Melvin Sharoky MD	Direttore	17 Agosto 2026 S	0	2	$-4.737.850
Clarissa Desjardins	Direttore	13 Maggio 2026 A	70.312	0	$0
Elizabeth M Anderson	Direttore	13 Maggio 2026 A	62.034	2	$-2.981.600
Leo Lee	Direttore	13 Maggio 2026 A	57.971	5	$-14.692.249
David W J Mcgirr	Direttore	09 Febbraio 2026 G	53.400	0	$0
Alfred Altomari	Direttore	13 Maggio 2024 A	69.495	0	$0
Steinar J Engelsen	Direttore	01 Novembre 2021 P	320.802	0	$0
Donald J Hayden JR	Direttore	09 Aprile 2019 M	62.197	0	$0
Myrtle S Potter	Direttore	15 Maggio 2018 A	25.510	0	$0
Randall W Whitcomb	Direttore	10 Marzo 2015 M	69.188	0	$0
Richard S Kollender	Direttore	31 Ottobre 2013 M	24.598	0	$0
Dennis M Lanfear	Direttore	09 Giugno 2010 A	168.404	0	$0
Graham K Crooke	Direttore	09 Giugno 2010 A	228.404	0	$0
Kenneth G Condon	Direttore	09 Giugno 2010 A	168.504	0	$0
FMR LLC	Proprietario del 10%	22 Luglio 2013 S	2.221	0	$0
Carol Schafer	·	13 Maggio 2026 A	66.622	0	$0

Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato

Proprietà ETF Posseduti da 73 ETF

20

Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.

Fondo	Peso	Unità	Aggiornato al	Fonte
MEDI · Harbor ETF Trust	2,52%	10.513 NS	31 Luglio 2026	N-PORT
IBB · iShares Trust	2,02%	1.640.771 SH	11 Settembre 2026	Giornaliero
IBBQ · Invesco Exchange-Traded Fund Trust …	1,63%	15.452 SH	01 Ottobre 2026	Giornaliero
SPIT · RBB Fund, Inc.	1,60%	5.414 NS	31 Luglio 2026	N-PORT
BBP · ETFis Series Trust I	1,39%	13.870 NS	31 Luglio 2026	N-PORT
JDOC · J.P. Morgan Exchange-Traded Fund Tr…	0,97%	894 NS	31 Luglio 2026	N-PORT
IWP · iShares Trust	0,80%	1.209.253 SH	11 Settembre 2026	Giornaliero
LABU · Direxion Shares ETF Trust	0,73%	36.726 NS	31 Luglio 2026	N-PORT
IYH · iShares Trust	0,44%	125.597 SH	11 Settembre 2026	Giornaliero
IMCG · iShares Trust	0,38%	118.553 SH	11 Settembre 2026	Giornaliero
WINN · Harbor ETF Trust	0,36%	40.917 NS	31 Luglio 2026	N-PORT
VHT · VANGUARD WORLD FUND	0,33%	632.581 SH	19 Agosto 2026	Giornaliero
VBK · VANGUARD INDEX FUNDS	0,32%	1.435.651 SH	19 Agosto 2026	Giornaliero
FHLC · FIDELITY COVINGTON TRUST	0,30%	100.200 NS	31 Luglio 2026	N-PORT
FFLG · FIDELITY COVINGTON TRUST	0,26%	15.672 NS	31 Luglio 2026	N-PORT
VXF · VANGUARD INDEX FUNDS	0,26%	2.487.127 SH	19 Agosto 2026	Giornaliero
VOT · VANGUARD INDEX FUNDS	0,25%	830.249 SH	19 Agosto 2026	Giornaliero
SIZE · iShares Trust	0,23%	7.660 SH	11 Settembre 2026	Giornaliero
PWS · Pacer Funds Trust	0,21%	502 NS	31 Luglio 2026	N-PORT
IWR · iShares Trust	0,20%	879.778 SH	11 Settembre 2026	Giornaliero
EUSA · iShares, Inc.	0,20%	29.864 SH	11 Settembre 2026	Giornaliero
HEQQ · J.P. Morgan Exchange-Traded Fund Tr…	0,19%	587 NS	31 Luglio 2026	N-PORT
IMCB · iShares Trust	0,19%	25.151 SH	11 Settembre 2026	Giornaliero
FFSM · FIDELITY COVINGTON TRUST	0,19%	28.857 NS	31 Luglio 2026	N-PORT
JMOM · J.P. Morgan Exchange-Traded Fund Tr…	0,15%	38.663 NS	31 Luglio 2026	N-PORT
VB · VANGUARD INDEX FUNDS	0,14%	2.485.842 SH	19 Agosto 2026	Giornaliero
ESLG · Strategy Shares	0,13%	313 NS	31 Luglio 2026	N-PORT
ESUM · Strategy Shares	0,13%	2.410 NS	31 Luglio 2026	N-PORT
LRND · New York Life Investments ETF Trust	0,12%	4.894 NS	31 Luglio 2026	N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust	0,12%	27.929 SH	01 Ottobre 2026	Giornaliero
ESLV · Strategy Shares	0,12%	171 NS	31 Luglio 2026	N-PORT
SUSA · iShares Trust	0,11%	35.904 SH	11 Settembre 2026	Giornaliero
VO · VANGUARD INDEX FUNDS	0,11%	2.348.570 SH	19 Agosto 2026	Giornaliero
USXF · iShares Trust	0,11%	12.482 SH	11 Settembre 2026	Giornaliero
SDG · iShares Trust	0,10%	1.340 SH	11 Settembre 2026	Giornaliero
ESSC · Strategy Shares	0,10%	368 NS	31 Luglio 2026	N-PORT
ILCG · iShares Trust	0,09%	20.984 SH	10 Settembre 2026	Giornaliero
EQAL · Invesco Exchange-Traded Fund Trust …	0,09%	5.928 SH	01 Ottobre 2026	Giornaliero
IWF · iShares Trust	0,08%	806.337 SH	11 Settembre 2026	Giornaliero
FBCG · FIDELITY COVINGTON TRUST	0,08%	53.285 NS	31 Luglio 2026	N-PORT
VONG · VANGUARD SCOTTSDALE FUNDS	0,07%	339.999 SH	19 Agosto 2026	Giornaliero
VUG · VANGUARD INDEX FUNDS	0,05%	1.801.856 SH	19 Agosto 2026	Giornaliero
DYNF · BlackRock ETF Trust	0,05%	147.228 SH	11 Settembre 2026	Giornaliero
ILCB · iShares Trust	0,04%	4.085 SH	11 Settembre 2026	Giornaliero
VFMO · VANGUARD WELLINGTON FUND	0,04%	7.753 SH	19 Agosto 2026	Giornaliero
ESGV · VANGUARD WORLD FUND	0,04%	48.501 SH	19 Agosto 2026	Giornaliero
IWB · iShares Trust	0,04%	148.337 SH	11 Settembre 2026	Giornaliero
IYY · iShares Trust	0,04%	9.185 SH	11 Settembre 2026	Giornaliero
ITOT · iShares Trust	0,04%	283.947 SH	11 Settembre 2026	Giornaliero
IWV · iShares Trust	0,04%	59.481 SH	11 Settembre 2026	Giornaliero
PBUS · Invesco Exchange-Traded Fund Trust …	0,04%	36.517 SH	01 Ottobre 2026	Giornaliero
BBUS · J.P. Morgan Exchange-Traded Fund Tr…	0,03%	29.520 NS	31 Luglio 2026	N-PORT
VOTE · TCW ETF Trust	0,03%	3.623 NS	31 Luglio 2026	N-PORT
BKLC · BNY Mellon ETF Trust	0,03%	17.548 NS	31 Luglio 2026	N-PORT
DFUS · Dimensional ETF Trust	0,03%	66.777 NS	31 Luglio 2026	N-PORT
TOK · iShares Trust	0,03%	583 SH	11 Settembre 2026	Giornaliero
VTI · VANGUARD INDEX FUNDS	0,03%	6.885.800 SH	19 Agosto 2026	Giornaliero
VONE · VANGUARD SCOTTSDALE FUNDS	0,03%	35.614 SH	19 Agosto 2026	Giornaliero
VTHR · VANGUARD SCOTTSDALE FUNDS	0,03%	18.072 SH	19 Agosto 2026	Giornaliero
TOV · EA Series Trust	0,03%	751 NS	31 Luglio 2026	N-PORT
URTH · iShares, Inc.	0,03%	18.868 SH	11 Settembre 2026	Giornaliero
RECS · Columbia ETF Trust I	0,03%	17.415 NS	31 Luglio 2026	N-PORT
ACWI · iShares Trust	0,03%	67.041 SH	11 Settembre 2026	Giornaliero
CRBN · iShares Trust	0,02%	2.066 SH	11 Settembre 2026	Giornaliero
VV · VANGUARD INDEX FUNDS	0,02%	126.924 SH	19 Agosto 2026	Giornaliero
VT · VANGUARD INTERNATIONAL EQUITY INDEX…	0,02%	178.900 SH	19 Agosto 2026	Giornaliero
TILT · FlexShares Trust	0,02%	4.108 NS	31 Luglio 2026	N-PORT
DFSU · Dimensional ETF Trust	0,02%	4.167 NS	31 Luglio 2026	N-PORT
DCOR · Dimensional ETF Trust	0,02%	5.993 NS	31 Luglio 2026	N-PORT
DFAU · Dimensional ETF Trust	0,01%	18.487 NS	31 Luglio 2026	N-PORT
HDUS · Lattice Strategies Trust	0,01%	250 NS	31 Luglio 2026	N-PORT
DFAC · Dimensional ETF Trust	0,01%	48.566 NS	31 Luglio 2026	N-PORT
SMLF · iShares Trust	·	124.879 SH	11 Settembre 2026	Giornaliero

INSM Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo

21

rating · 30 analisti COMPRA

Target mediano $195.00 +75,5%

9 30,0% Acquisto forte

20 66,7% Compra

1 3,3% Mantieni

0 0,0% Vendi

0 0,0% Vendita forte

Target Price a 12 Mesi

23 analisti · 2026-09-29

Target medio $199.04 +79,1%

← Sotto tutti i target Prezzo attuale $111.12

Basso$169.00 Media$199.04 Alto$243.00

Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore

22

Base FY, prezzi alla chiusura dell'ultimo anno fiscale di ciascuna società.

Ticker	Capitalizzazione di Mercato	P/E	Rev YoY	Margine Netto	ROE	Margine lordo
INSM	$37.29B	-27.1	66.7%	-210.5%	-128.4%	·
NTRA	$32.00B	-150.7	35.9%	-9.0%	-14.1%	·
RVMD	·	·	·	·	·	·
BIIB	$25.84B	20.0	2.2%	13.1%	7.2%	·
ALNY	$52.64B	170.7	65.2%	8.5%	60.4%	·
UTHR	$21.27B	17.5	10.6%	41.9%	18.7%	87.9%
INCY	$19.60B	15.4	21.2%	25.0%	27.6%	·
NBIX	$14.20B	30.4	21.4%	16.7%	16.1%	·
EXEL	$11.44B	15.7	7.0%	33.7%	37.3%	·
SMMT	$13.56B	-12.1	·	·	-235.1%	·

Ultime notizie Notizie recenti che menzionano questa società

23

Is Insmed (INSM) One of the Most Promising Healthcare Stocks After Cantor Fitzgerald’s Target Raise? Yahoo Finance · 3 mesi, 1 settimana fa Pressioni Competitive Spingono Truist a Ridurre l'Obiettivo su Insmed (INSM) Yahoo Finance · 4 mesi, 1 settimana fa Insmed CEO rivela che la popolazione di pazienti giapponesi supera il mercato statunitense per la malattia polmonare Yahoo Finance · 6 mesi, 1 settimana fa Artisan Small Cap Fund ha Venduto Insmed (INSM) in Base alla Valutazione Yahoo Finance · 6 mesi, 2 settimane fa

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INSM Insmed Incorporated - Common Stock