LXRX Snapshot del titolo Prezzo, capitalizzazione di mercato, P/E, EPS, ROE, debito/capitale proprio, intervallo 52 settimane

03
Prezzo $1.82
Capitalizzazione di Mercato (MRQ) $813M
P/E (TTM) -12.1
EPS (TTM) $-0.15
Ricavi (TTM) $41M
ROE (TTM) -40.2%
D/E Debito/Patrimonio (MRQ) 0.3
Intervallo 52 sett. $1–$3

LXRX Grafico del prezzo delle azioni OHLCV giornaliero con indicatori tecnici — panoramica, zoom e personalizza la tua visualizzazione

04
intervallo
barre

La granularità delle barre si adatta al periodo selezionato — passa il mouse sul grafico per vedere apertura/massimo/minimo/chiusura di una barra.

Split azionari 1
Data ex-dividendo Split Tipo
21 Maggio 2015 1-for-7 Inverso

Informazioni su Lexicon Pharmaceuticals, Inc. - Common Stock Panoramica della società da Wikipedia

05 · wikidata

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its mouse gene knockout technology and in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 100 potential therapeutic targets. Lexicon has advanced multiple drug candidates into human clinical trials and has a broad and diverse pipeline of drug targets behind its clinical programs. Lexicon is pursuing drug targets in five therapeutic areas including oncology, gastroenterology, immunology, metabolism, and ophthalmology.

The company's clinical drug candidates include sotagliflozin (LX4211) for the treatment of type 2 diabetes; LX1033 for the treatment of irritable bowel syndrome and other gastrointestinal disorders; telotristat ethyl (LX1032) for the treatment of the symptoms associated with carcinoid syndrome; and LX2931 for the treatment of autoimmune diseases, such as rheumatoid arthritis.

Company history

Lexicon Pharmaceuticals was founded in September 1995 as a biotech venture of Baylor College of Medicine. The company went public in April 2000 with $220 million initial public offerings. In June, 2001 Lexicon purchased a privately owned small chemical library synthesis company, Coelacanth Corporation in Princeton, New Jersey, which became the site for the company's small molecule and medicinal chemistry efforts. The company's original name was Lexicon Genetics Incorporated, but in 2007, the name changed to Lexicon Pharmaceuticals, Inc. to reflect a renewed focus on drug development.

The company initially focused on using gene knockout technology to define the function of genes. This effort complemented and benefited from the international effort to sequence the human and mouse genomes (see Human Genome Project). Using its proprietary gene trapping and gene targeting technologies, the company created A repository of genetically modified mouse embryonic stem cells, known as OmniBank, and established a large-scale mammalian knockout program to discover the physiological and behavioral functions of the most druggable mammalian genes. The information collected from this program is stored in the company's LexVision database, which contains almost 5,000 gene knockouts studied. Over the years, Lexicon evolved from a genomics company into a drug discovery and development company focused on discovering and developing treatments for human disease. The company currently has multiple drug candidates in various stages of clinical trials.

In 2016, the company was ranked #8 on the Deloitte Fast 500 North America list.

Technology

Lexicon uses patented gene trapping and gene targeting technologies to generate and study knockout mice to discover the physiological and behavioral effects that result from the disruption of a single gene knockout. Because there is a close similarity in gene function and physiology between mice and humans, with a large majority of human genes having a counterpart in the mouse genome, knockout mouse technology has become a powerful tool in the discovery of new medicines.

The value of Lexicon's technology in drug discovery has been described in a retrospective analysis by the scientific journal Nature. The conclusion of this analysis was that, in most cases, there was a direct correlation when comparing the physiological characteristics, or phenotypes, of knockout mice to the therapeutic effect of the 100 best-selling drugs of 2001. The tremendous utility of knockout mouse technology was recognized in 2007 with the Nobel Prize in Physiology or Medicine to Drs. Mario Capecchi, Martin Evans, and Oliver Smithies.

In developing small molecule drugs for its validated targets, Lexicon uses medicinal chemistry known as "click chemistry." Dr. K. Barry Sharpless, who was awarded the 2001 Nobel Prize in Chemistry, developed this tools for the rapid synthesis of novel compounds. Lexicon uses solution-phase chemistry to generate diverse libraries of optically pure compounds that are built using organic reactions that allow the company to generate collections of different compounds and to tailor the compound collections to address various therapeutic target families. Lexicon's medicinal chemists design these libraries by analyzing the chemical structures of drugs that have been proven safe and effective against human disease and using that knowledge in the design of scaffolds and chemical building blocks for the generation of large numbers of new drug-like compounds.

Locations

Lexicon operates from two locations found in Texas and New Jersey. The corporate headquarters are in The Woodlands, Texas just north of Houston. This location serves as Lexicon's primary research facility to discover and validate the company's drug targets and test drug candidates in preclinical research. The company's clinical development and regulatory team is also based at the corporate headquarters.

Lexicon's campus in Princeton, New Jersey is the home of Lexicon's small molecule medicinal chemistry and preclinical development efforts. This site serves as Lexicon's primary medicinal chemistry site to create new chemical entities for therapeutic development.

== References ==

Fonte: Wikipedia (Inglese), CC BY-SA 4.0 · Vedi su Wikipedia ↗

Wikidata ↗

settoreHealthcare industriaPharmaceuticals dipendenti81 paeseUS

Performance decennale Andamento di ricavi, utile netto, margini e EPS

06
Ricavi$50M
2016-12-31 → 2025-12-31
EPS$-0.14
2017-12-31 → 2025-12-31
Flusso di cassa libero$-68M
2016-12-31 → 2025-12-31
Margine netto-147.4%
2016-12-31 → 2025-12-31
Valutazione e Rapporti 07–12

Valutazione Rapporti P/E, P/S, P/B, EV/EBITDA — il titolo è costoso o economico?

Metrica Tendenza 5 anni LXRX media 5 anni Mediana dei peer Verdetto
P/E (TTM) -12.1media 5 anni ≈-4.2 ≈-4.2 · ·
P/S (TTM) 19.6media 5 anni ≈1530.9 ≈1530.9 6.6 Sopravvalutato
P/B (MRQ) 4.7media 5 anni ≈4.1 ≈4.1 3.8 Sopravvalutato
EV / EBITDA (TTM) -12.5 · · ·
Price / FCF (Prezzo / FCF) -9.8media 5 anni ≈-5.6 ≈-5.6 · ·
Price / Cash Flow (Prezzo / Flusso di cassa) -9.8media 5 anni ≈-5.7 ≈-5.7 · ·
EV / Ricavi (TTM) 16.3 · · ·
EV / FCF -9.2 · · ·
Price / Tangible Book (Prezzo / Valore contabile tangibile) 10.6media 5 anni ≈6.7 ≈6.7 · ·

La mediana dei peer viene calcolata su base standardizzata per metrica e potrebbe non corrispondere sempre alla base TTM/MRQ mostrata per questo titolo.

valore · ≈ media 5 anni · mediana del settore · giudizio rispetto alla mediana

Cronologia utili EPS effettivo vs stima, surprise %, tasso di superamento, data prossimi utili

14
Sorpresa media 48.2%
Prossimo report Nov 13, 2026
PeriodoRapportoEPS ActualEPS StimatoSorpresa
30 Giugno 2026 Ago 4, 2026 $-0.07 $-0.05 -36.7%
31 Marzo 2026 Mag 11, 2026 $0.00 $-0.04 100.0%
31 Dicembre 2025 $-0.04 $-0.07 43.2%
30 Settembre 2025 $-0.04 $-0.07 40.6%
30 Giugno 2025 $0.01 $-0.08 112.6%
31 Marzo 2025 $-0.07 $-0.10 29.6%

Fondamentali Completi Tutte le metriche per anno — conto economico, stato patrimoniale, rendiconto finanziario

15
Conto Economico 16
Metrica Tendenza 202520242023202220212020201920182017201620152014
Revenue $50M$31M$1M$139.0K$298.0K$24M$322M$63M$92M$79M$130M$23M
Cost of Revenue $274.0K$616.0K$85.0K$0$0$2M$3M$2M$2M$0$0·
R&D Expense $61M$84M$59M$53M$55M$154M$92M$100M$152M$164M$95M$89M
SG&A Expense $37M$143M$114M$48M$32M$47M$57M$64M$66M$43M$24M$19M
Operating Expenses $99M$228M$173M$101M$87M$204M$181M$166M$222M$206M$129M$123M
Operating Income $-49M$-197M$-172M$-101M$-87M$-48M$141M$-103M$-131M$-127M$1M$-100M
Interest Expense ···$3M$802.0K$15M$21M$21M$7M$7M$7M$2M
Other Non-op $7M$12M$8M$2M$134.0K$3M$3M$4M$2M$2M$572.0K$2M
Pretax Income ····$-88M$-59M$124M$-121M$-136M$-131M$-5M$-100M
Income Tax ·$0$0$0$0····$0$0$-70.0K
Net Income $-50M$-200M$-177M$-102M$-88M$-59M$130M$-121M$-123M$-131M$-5M$-100M
EPS (Basic) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.23$-1.14$-1.17···
EPS (Diluted) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.16$-1.14$-1.17···
Shares (Basic) 363,053,000320,031,000221,130,000165,733,000145,652,000·······
Shares (Diluted) 363,053,000320,031,000221,130,000165,733,000145,652,000110,841,000116,747,000105,830,000105,237,000···
EBITDA $-48M$-197M$-171M$-100M$-87M$-45M$145M$-100M$-133M$-135M·$-98M
Stato Patrimoniale 30
Metrica Tendenza 202520242023202220212020201920182017201620152014
Cash & Equivalents $34M$67M$22M$46M$64M$126M$36M$80M$62M$47M$203M$137M
Short-term Investments $62M$171M$148M$92M$23M$26M$236M$80M$249M$300M$318M$202M
Receivables $2M$3M$1M$28.0K$14.0K$395.0K$57M$6M$5M$7M$911.0K$1M
Inventory $281.0K$231.0K$381.0K$0·$0$4M$5M$2M$0··
Other Current Assets $3M$5M$5M$2M$2M$5M$5M$3M$4M$4M$10M$5M
Current Assets $102M$246M$177M$141M$89M$158M$338M$173M$322M$358M$532M$369M
PP&E (Net) $2M$2M$2M$2M$1M$295.0K$14M$16M$18M$19M$21M$1M
PP&E (Gross) $5M$5M$7M$6M$6M$6M$76M$76M$76M$79M$81M$37M
Accum. Depreciation $3M$2M$5M$4M$5M$6M$62M$60M$59M$60M$59M$36M
Goodwill $45M$45M$45M$45M$45M$45M$45M$45M$45M$45M$45M$45M
Intangibles ······$20M$50M$52M$53M$53M$53M
Other Non-current Assets $368.0K$368.0K$828.0K$412.0K$2M$1M$2M$285.0K$429.0K$461.0K$433.0K$3M
Total Assets $185M$298M$229M$194M$137M$204M$418M$284M$437M$476M$652M$471M
Accounts Payable $3M$15M$14M$10M$9M$5M$12M$12M$39M$53M$20M$13M
Accrued Liabilities $13M$30M$17M$13M$13M$30M$42M$21M$12M$32M$25M$10M
Current Liabilities $21M$45M$32M$23M$22M$47M$65M$37M$105M$165M$123M$45M
Capital Leases $7M$5M$5M$5M········
Deferred Tax ······$0$6M$6M$19M$19M$19M
Other Non-current Liabilities $7M$7M$5M$5M$1M$611.0K$1M$238.0K$292.0K$805.0K$14M$24M
Total Liabilities $77M$152M$136M$77M$23M$47M$301M$311M$368M$318M$366M$187M
Long-term Debt $54M$100M·$49M$0$12M$249M$250M$252M$101M$106M$108M
Total Debt $54M$100M$100M·$0$12M$245M$245M$246M$101M·$108M
Common Stock $366.0K$363.0K$245.0K$189.0K$150.0K$142.0K$106.0K$106.0K$106.0K$105.0K$104.0K$104.0K
Paid-in Capital $2.13B$2.12B$1.86B$1.71B$1.61B$1.56B$1.46B$1.45B$1.44B$1.41B$1.40B$1.39B
Retained Earnings $-2.02B$-1.97B$-1.77B$-1.59B$-1.49B$-1.40B$-1.34B$-1.47B$-1.37B$-1.25B$-1.11B$-1.10B
Treasury Stock $5M$5M$3M$2M$8M$5M$4M$3M$2M$3M$3M$2M
AOCI $30.0K$119.0K$31.0K$-428.0K$-10.0K$-6.0K$84.0K$-12.0K$-222.0K$-195.0K$-219.0K$-63.0K
Stockholders' Equity $108M$146M$93M$117M$114M$156M$117M$-26M$68M$168M$286M$284M
Liabilities + Equity $185M$298M$229M$194M$137M$204M$418M$284M$437M$476M$652M$471M
Shares Outstanding 365,848,216363,020,303·189,214,000150,082,000142,289,000106,679,000106,162,000105,711,000104,582,000103,860,000103,663,000
Flusso di cassa 17
Metrica Tendenza 202520242023202220212020201920182017201620152014
D&A $621.0K$534.0K$554.0K$427.0K$292.0K$3M$4M$4M$3M$2M$727.0K$2M
Stock-based Comp $13M$13M$14M$12M$11M$13M$14M$12M$9M$7M$7M$7M
Deferred Tax ···$0$0$0$-6M$0$-13M$0$0$-70.0K
Amort. of Intangibles ·······$2M$2M···
Other Non-cash $-31M$8M$328.0K$1M$-10M$-101M$-28M$-43M$-57M$-44M·$16M
Operating Cash Flow $-68M$-179M$-162M$-89M$-87M$-143M$114M$-149M$-185M$-176M$185M$-76M
CapEx $0$1M$470.0K$1M$1M$87.0K$70.0K$95.0K$228.0K$231.0K$910.0K$80.0K
Investing Cash Flow $113M$-15M$-50M$-71M$2M$381M$-156M$170M$51M$18M$-117M$-108M
Debt Issued $0$0$50M$49M·$0$0$13M$146M$0$0$84M
Net Debt Issued $0$0·$49M$-12M$-217M$-1M$-2M$144M$-2M·$82M
Stock Issued $0$0$139M$94M$37M$70M$0$732.0K$8M$4M$114.0K$202M
Stock Repurchased ·$2M$824.0K$864.0K$3M$1M$941.0K$972.0K$2M$621.0K$357.0K$887.0K
Net Stock Activity $0$-2M$138M$93M$34M$69M$-941.0K$-240.0K$6M$3M·$201M
Financing Cash Flow $-48M$238M$188M$142M$23M$-148M$-2M$-2M$150M$987.0K$-2M$284M
Net Change in Cash $-3M$44M$-24M$-18M$-62M$90M$-44M$19M$15M$-156M$66M$100M
Free Cash Flow $-68M$-180M$-162M$-90M$-88M$-143M$114M$-149M$-186M$-176M·$-76M
Levered FCF ·········$-182M·$-78M
Redditività 7
Metrica Tendenza 202520242023202220212020201920182017201620152014
Operating Margin -98.2%-634.2%-14264.9%-72489.2%-29224.8%-199.2%43.9%-163.4%-151.3%-164.6%·-439.2%
Net Margin -101.1%-644.8%-14710.9%-73341.0%-29449.0%-244.1%40.4%-190.7%-142.9%-169.7%·-438.8%
Pretax Margin ····-29449.0%-244.1%38.5%-190.7%-156.9%-169.7%·-439.1%
EBITDA Margin -97.0%-632.5%-14218.9%-72182.0%-29126.9%-187.0%45.1%-157.6%-147.5%-162.1%·-430.7%
ROA -20.8%-75.9%-83.6%-61.6%-51.5%-18.9%37.1%-33.5%-28.3%-25.1%·-26.9%
ROE -39.7%-167.7%-168.5%-88.4%-65.0%-42.8%287.0%-576.0%-117.5%-63.8%·-44.2%
ROIC ·········-53.0%·-25.6%
Liquidità e Solvibilità 5
Metrica Tendenza 202520242023202220212020201920182017201620152014
Current Ratio 4.95.45.66.14.03.45.24.72.62.2·8.2
Quick Ratio 4.75.35.46.03.93.35.04.52.52.2·7.6
Debt / Equity 0.50.71.1·0.00.12.1-9.34.70.6·0.4
LT Debt / Equity 0.50.71.1··0.02.0-9.24.40.5·0.3
Interest Coverage ···-36.2-108.6-3.36.8-5.0-19.6-20.9·-44.5
Efficienza 3
Metrica Tendenza 202520242023202220212020201920182017201620152014
Asset Turnover 0.20.10.00.00.00.10.90.20.20.1·0.1
Inventory Turnover 1.12.00.4··0.90.70.81.9···
Receivables Turnover 17.013.92.36.61.50.810.311.814.719.8·25.0
Per Azione 5
Metrica Tendenza 202520242023202220212020201920182017201620152014
Book Value / Share $0.29··$0.62$0.76$1.10$1.10$-0.25$0.49$1.50·$0.39
Revenue / Share $0.14$0.10$0.01·$0.00$0.22$2.76·····
Cash Flow / Share $-0.19$-0.56$-0.73·$-0.60$-1.29$0.97·····
Cash / Share $0.09··$0.24$0.43$0.89$0.34$0.76$0.58$0.45·$0.19
EPS (TTM) $-0.14$-0.63$-0.80$-0.62$-0.60$-0.53$1.16$-1.14$-1.17$-0.12$-0.12·
Tassi di Crescita 3
Metrica Tendenza 202520242023202220212020201920182017201620152014
Revenue YoY 60.2%2481.5%766.2%-53.4%-98.8%·······
Revenue CAGR 3Y 610.2%370.7%-63.1%·········
Revenue CAGR 5Y 15.7%···········
Valutazione (TTM) 14
Metrica Tendenza 202520242023202220212020201920182017201620152014
Revenue TTM $50M$31M$1M$139.0K$298.0K$24M$322M$63M$92M$79M$130M$23M
Net Income TTM $-50M$-200M$-177M$-102M$-88M$-59M$130M$-121M$-123M$-131M$-5M$-100M
Market Cap $421M··$361M$591M$487M$443M$705M$1.04B$1.45B·$4.62B
Enterprise Value $378M···$505M$346M$416M$790M$979M$1.20B·$4.39B
P/E -8.2-1.2-1.9-3.1-6.6-6.53.6-5.8-8.4-115.2-110.9·
P/S 8.4··2600.01984.320.31.411.211.418.2·202.3
P/B 3.9··3.15.23.13.8-26.720.09.2·16.3
P / Tangible Book 6.7··5.08.64.4······
P / Cash Flow -6.2··-4.1-6.8-3.43.9-4.7-5.6-8.2·-61.1
P / FCF -6.2··-4.0-6.7-3.43.9-4.7-5.6-8.2·-61.1
EV / EBITDA -7.8···-5.8-7.72.9-7.9-7.3-8.9·-44.6
EV / FCF -5.6···-5.7-2.43.7-5.3-5.3-6.8·-58.0
EV / Revenue 7.6···1693.214.41.312.510.715.2·192.1
Earnings Yield -12.2%-85.1%-52.3%-32.5%-15.2%-15.5%28.0%-17.2%-11.8%-0.87%-0.90%·

Periodo più recente a sinistra · valori nulli mostrati come ·

Bilanci Conto economico, stato patrimoniale, flusso di cassa — annuale, ultimi 5 anni

16
Metrica 2025-12-312024-12-312023-12-312022-12-312021-12-31
Ricavi $50M $31M $1M $139.0K $298.0K
Margine Operativo % -98.2% -634.2% -14264.9% -72489.2% -29224.8%
Utile netto $-50M $-200M $-177M $-102M $-88M
EPS Diluito $-0.14 $-0.63 $-0.80 $-0.62 $-0.60

Proprietari istituzionali (13F) 167 filer · $890.0M totale · Aggiornato al 30 Giugno 2026

17

Istituzioni che segnalano il possesso di questo titolo nel loro Modulo SEC 13F trimestrale. Solo posizioni lunghe; un singolo depositante può apparire due volte per diverse gambe di opzioni. Grandi posizioni put/call contrapposte riflettono tipicamente market-making o inventario coperto, non convinzione direzionale.

Detentori 167
Valore detenuto $890.0M
Nuove posizioni 43
Posizioni chiuse 27
Attività istituzionale — Q2 2026 vs trimestre precedente
Nuove posizioni Posizioni chiuse Aumentato Diminuito Variazione netta delle azioni
43 (+9 vs trimestre precedente) 27 (+14 vs trimestre precedente) 39 (-5 vs trimestre precedente) 38 (+14 vs trimestre precedente) +42.4M

Confrontato con Q1 2026. Le dichiarazioni SEC Form 13F sono dovute entro 45 giorni dalla fine del trimestre più un breve margine per i dichiaranti in ritardo — i trimestri ancora all'interno di questa finestra vengono saltati a favore della coppia più recente completamente riportata.

Istituzione Valore Azioni % di 13F tracciati Tipo
Artal Group S.A. $420.374.549 175.156.062 47,23% Azioni
FMR LLC $124.276.907 51.782.045 13,96% Azioni
Siren, L.L.C. $106.328.443 44.303.518 11,95% Azioni
Sessa Capital IM, L.P. $45.506.006 18.960.836 5,11% Azioni
BlackRock, Inc. $41.636.978 17.348.741 4,68% Azioni
VANGUARD CAPITAL MANAGEMENT LLC $23.762.899 9.901.208 2,67% Azioni
Point72 Asset Management, L.P. $19.803.180 8.251.325 2,23% Azioni
GEODE CAPITAL MANAGEMENT, LLC $14.989.739 6.244.372 1,68% Azioni
STATE STREET CORP $11.802.646 4.917.769 1,33% Azioni
VANGUARD GROUP INC $11.047.532 9.606.549 1,24% Azioni
VANGUARD PORTFOLIO MANAGEMENT LLC $5.658.598 2.357.749 0,64% Azioni
NORTHERN TRUST CORP $4.724.686 1.968.619 0,53% Azioni
CHARLES SCHWAB INVESTMENT MANAGEMENT INC $4.696.260 1.956.775 0,53% Azioni
VANGUARD FIDUCIARY TRUST CO $3.922.970 1.634.571 0,44% Azioni
CITADEL ADVISORS LLC $3.842.837 1.601.182 0,43% Azioni
CIBC Private Wealth Group LLC $3.240.347 2.400.257 0,36% Azioni
Ishara Investments LP $3.050.400 1.271.000 0,34% Azioni
MILLENNIUM MANAGEMENT LLC $2.722.150 1.134.229 0,31% Azioni
RENAISSANCE TECHNOLOGIES LLC $2.704.800 1.127.000 0,30% Azioni
MACKENZIE FINANCIAL CORP $2.312.050 963.354 0,26% Azioni
ADAR1 Capital Management, LLC $1.800.000 750.000 0,20% Azioni
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1.672.262 696.776 0,19% Azioni
UBS Group AG $1.643.312 684.713 0,18% Azioni
SUSQUEHANNA INTERNATIONAL GROUP, LLP $1.604.400 668.500 0,18% Opzione Call
TWO SIGMA INVESTMENTS, LP $1.544.266 643.444 0,17% Azioni
Nuveen, LLC $1.407.994 586.664 0,16% Azioni
JANE STREET GROUP, LLC $1.398.960 582.900 0,16% Opzione Call
Bank of New York Mellon Corp $1.364.893 568.706 0,15% Azioni
Invesco Ltd. $1.219.370 508.071 0,14% Azioni
GOLDMAN SACHS GROUP INC $1.165.310 485.546 0,13% Azioni
Compagnie Lombard Odier SCmA $1.152.000 480.000 0,13% Azioni
BANK OF AMERICA CORP /DE/ $1.011.117 421.299 0,11% Azioni
BARCLAYS PLC $929.960 387.483 0,10% Azioni
CITADEL ADVISORS LLC $886.320 369.300 0,10% Opzione Call
XTX Topco Ltd $858.905 357.877 0,10% Azioni
CANADA PENSION PLAN INVESTMENT BOARD $618.960 257.900 0,07% Azioni
RHUMBLINE ADVISERS $616.523 256.885 0,07% Azioni
DEUTSCHE BANK AG\ $594.068 247.528 0,07% Azioni
WELLS FARGO & COMPANY/MN $553.128 230.470 0,06% Azioni
WELLINGTON MANAGEMENT GROUP LLP $431.280 179.700 0,05% Azioni
CITIGROUP INC $420.492 175.205 0,05% Azioni
GROUP ONE TRADING LLC $420.031 175.013 0,05% Azioni
Virtus Investment Advisers, LLC $408.996 170.415 0,05% Azioni
Headlands Technologies LLC $401.275 167.198 0,05% Azioni
Ikarian Capital, LLC $395.218 164.674 0,04% Azioni
Quarry LP $374.846 156.186 0,04% Azioni
MetLife Investment Management, LLC $351.384 146.410 0,04% Azioni
MORGAN STANLEY $318.964 132.902 0,04% Azioni
PANAGORA ASSET MANAGEMENT INC $316.901 132.042 0,04% Azioni
JPMORGAN CHASE & CO $289.975 109.839 0,03% Azioni

Mostra tutti i 167 proprietari istituzionali →

Attivisti e proprietari del 5%+ 11 partecipazioni

18

Investitori che hanno depositato SEC Schedule 13D — proprietà effettiva superiore al 5% con l'intento di influenzare l'emittente (partecipazioni attiviste, campagne per il consiglio di amministrazione, M&A). Ogni riga mostra lo stato più recente noto della posizione di quel depositante.

Depositante Depositato Partecipazione Stato Scopo Deposito
Invus, L.P., Invus Advisors, L.L.C., Invus Public Equities, L.P., Invus Public Equities Advisors, LLC, Invus Global Management, LLC, Siren, L.L.C., Avicenna Life Sci Master Fund LP, Avicenna Life Sci Master GP LLC, Invus US Partners LLC, Ulys, L.L.C., Raymond Debbane, Artal Participations S.a r.l., Artal International S.C.A., Artal International Management S.A., Artal Group S.A., Westend S.A., Stichting Administratiekantoor Westend, Amaury Wittouck ×7 depositi 08 Maggio 2026 39,40% Modifica · SEC
Invus, L.P. (2), Invus Advisors, L.L.C. (2), Invus Public Equities, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Global Management, LLC (2), Siren, L.L.C. (2), Artal Participations S.à r.l. (2), Artal International S.C.A. (2), Artal International Management S.A. (2), Artal Group S.A. (2), Westend S.A. (2), Stichting Administratiekantoor Westend (2), Mr. Amaury Wittouck (2), Invus US Partners LLC (2), Ulys, L.L.C. (2), Mr. Raymond Debbane (2) ×15 depositi 09 Dicembre 2024 · Deposito iniziale · SEC
24 Febbraio 2012 · Deposito iniziale · SEC
Raymond Debbane (2), Ulys, L.L.C. (2), Invus Advisors, L.L.C. (2), Invus, L.P. (2), Invus Public Equities Advisors, LLC (2), Invus Public Equities, L.P. (2), Invus C.V. (2) 27 Dicembre 2011 · Deposito iniziale · SEC
14 Novembre 2011 · Deposito iniziale · SEC
15 Agosto 2011 · Deposito iniziale · SEC
Raymond Debbane, Ulys, L.L.C., Invus Advisors, L.L.C., Invus, L.P., Invus Public Equities Advisors, LLC, Invus Public Equities, L.P., Invus C.V. 19 Marzo 2010 · Deposito iniziale Struttura del capitale SEC
Estate of Gordon A. Cain (, Mary H. Cain ×4 depositi 05 Agosto 2005 · Deposito iniziale · SEC
Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata 08 Agosto 2003 · Deposito iniziale · SEC
Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata 18 Luglio 2003 · Deposito iniziale Investimento passivo SEC
Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata, Persona segnalante non divulgata 19 Marzo 2003 · Deposito iniziale · SEC

Purpose is an automated classification of the filer's own stated purpose (SEC Item 4) — not investment advice. "—" means no clear purpose was stated or the text could not be classified.

Insider aziendali 49 insider · 32 dirigenti · 19 direttori

19
Insider Ruolo Ultima attività Azioni possedute Acquisti 12m Vendite 12m Netto 12m
Michael Exton Chief Executive Officer 28 Febbraio 2026 M 298.432 0 0 $0
Lonnel Coats Chief Executive Officer 28 Febbraio 2024 M 1.098.068 0 0 $0
Arthur T Sands President & CEO 28 Febbraio 2014 M 1.021.329 0 0 $0
Scott M Coiante SVP, Chief Financial Officer 28 Febbraio 2026 M 105.356 0 0 $0
Ajay Bansal EVP Corp Dev and CFO 02 Giugno 2009 A · 0 0 $0
Julia P Gregory EVP and CFO 07 Febbraio 2008 A 50.200 0 0 $0
Jeffrey L Wade President and COO 08 Luglio 2024 A 324.214 0 0 $0
Rachel Yap Martens SVP, Partnerships & Corp Strat 28 Febbraio 2026 M 31.264 0 0 $0
Suma Gopinathan SVP, Discovery 28 Febbraio 2026 M 150.132 0 0 $0
Wendy Mcdermott SVP, Human Resources 28 Febbraio 2026 M 277.945 0 0 $0
Craig B Granowitz SVP, Chief Medical Officer 28 Febbraio 2026 M 323.430 0 0 $0
Lisa Defrancesco SVP, IR and Corp Comm 28 Febbraio 2026 M 93.869 0 0 $0
Brian T Crum SVP, General Counsel & Secr. 28 Febbraio 2026 M 428.802 0 0 $0
Kristen Alexander VP, Finance and Accounting 28 Febbraio 2025 M 76.368 0 0 $0
Alan J Main EVP, Innov & Chem Sciences 28 Febbraio 2025 M 339.104 0 0 $0
Brian Corrigan SVP, Regulatory & QA 13 Febbraio 2025 A · 0 0 $0
Kenneth B. Kassler-Taub SVP, Regulatory & QA 28 Febbraio 2024 M 162.672 0 0 $0
Thomas Garner SVP, Chief Commercial Officer 08 Febbraio 2024 A · 0 0 $0
Kiernan Seth VP, Chief Commercial Officer 28 Febbraio 2023 M 53.136 0 0 $0
James F Tessmer VP, Finance & Accounting 15 Marzo 2021 M 71.766 0 0 $0
Alexander A Santini EVP and CCO 22 Aprile 2020 F 55.584 0 0 $0
Pablo Lapuerta EVP and CMO 22 Aprile 2020 F 85.719 0 0 $0
John Northcott VP, Marketing, Comm Strategy 02 Marzo 2015 M 8.235 0 0 $0
Brian P Zambrowicz EVP, Chief Scientific Officer 28 Febbraio 2014 M 278.703 0 0 $0
Steven Alan Tragash VP, Corporate Affairs 15 Febbraio 2010 A · 0 0 $0
Philip M Brown SVP, Clinical Development 15 Febbraio 2010 A 27.306 0 0 $0
James R Piggott PHD SVP of Pharm Bio 07 Febbraio 2008 A 0 0 0 $0
Lance K Ishimoto SVP, Intellectual Property 07 Febbraio 2008 A 10.200 0 0 $0
Tamar D Howson EVP of Bus Dev 07 Febbraio 2008 A · 0 0 $0
Walter F Colbert SVP, HR and Corp Serv 13 Febbraio 2007 A · 0 0 $0
Randall B Riggs SVP, Corp Licensing 23 Febbraio 2004 M 15.000 0 0 $0
Christophe Person VP Informatics 12 Gennaio 2004 M 0 0 0 $0
Ivan Cheung Direttore 03 Giugno 2026 M 89.312 0 0 $0
Diane E. Sullivan Direttore 03 Giugno 2026 M 126.122 0 0 $0
Judith L Swain Direttore 03 Giugno 2026 M 174.486 0 0 $0
Amouyal Philippe Direttore 03 Giugno 2026 M 374.486 0 0 $0
Sam L Barker Direttore 03 Giugno 2026 M 213.771 0 0 $0
Christopher J Sobecki Direttore 03 Giugno 2026 M 293.177 0 0 $0
Raymond Debbane Direttore 03 Giugno 2026 M 1.995.498 7 0 $723.048
Robert J Lefkowitz MD Direttore 13 Maggio 2024 A 48.364 0 0 $0
Frank Palantoni Direttore 21 Maggio 2023 M 40.332 0 0 $0
Alan S Nies Direttore 21 Maggio 2023 M 41.046 0 0 $0
Invus C.V. Direttore 31 Dicembre 2020 J 0 0 0 $0
Kathleen M Wiltsey Direttore 24 Aprile 2009 A · 0 0 $0
Clayton Stuart Rose Direttore 26 Giugno 2007 P 25.000 0 0 $0
Barry Mills Direttore 26 Aprile 2007 A 25.000 0 0 $0
Patricia M Cloherty Direttore 27 Aprile 2006 A · 0 0 $0
Thomas C Caskey Direttore 13 Ottobre 2005 P 6.300 0 0 $0
Praveen Tyle · 28 Febbraio 2021 M 120.791 0 0 $0

Insider dai depositi SEC Modulo 3/4/5; netto = solo acquisti/vendite di mercato

Proprietà ETF Posseduti da 16 ETF

20

Il peso riflette solo le partecipazioni azionarie dirette (N-PORT); fondi a leva o basati su derivati possono detenere ulteriore esposizione swap non mostrata.

Fondo Peso Unità Aggiornato al Fonte
BBC · ETFis Series Trust I 0,81% 161.882 NS 31 Luglio 2026 N-PORT
PILL · Direxion Shares ETF Trust 0,45% 40.310 NS 31 Luglio 2026 N-PORT
QQQS · Invesco Exchange-Traded Fund Trust … 0,42% 53.319 SH 02 Ottobre 2026 Giornaliero
IWC · iShares Trust 0,12% 842.323 SH 11 Settembre 2026 Giornaliero
VTWG · VANGUARD SCOTTSDALE FUNDS 0,04% 266.401 SH 19 Agosto 2026 Giornaliero
IWO · iShares Trust 0,03% 2.343.443 SH 11 Settembre 2026 Giornaliero
VTWO · VANGUARD SCOTTSDALE FUNDS 0,02% 1.432.882 SH 19 Agosto 2026 Giornaliero
RSSL · Global X Funds 0,02% 118.391 NS 31 Luglio 2026 N-PORT
PRFZ · Invesco Exchange-Traded Fund Trust 0,02% 255.130 SH 02 Ottobre 2026 Giornaliero
IWM · iShares Trust 0,02% 6.319.224 SH 11 Settembre 2026 Giornaliero
VXF · VANGUARD INDEX FUNDS 0,01% 2.594.934 SH 19 Agosto 2026 Giornaliero
VHT · VANGUARD WORLD FUND 0,01% 637.561 SH 19 Agosto 2026 Giornaliero
WSML · iShares Trust 0,01% 17.992 SH 11 Settembre 2026 Giornaliero
IWV · iShares Trust 0,00% 85.389 SH 03 Settembre 2026 Giornaliero
VTI · VANGUARD INDEX FUNDS 0,00% 7.083.651 SH 19 Agosto 2026 Giornaliero
VTHR · VANGUARD SCOTTSDALE FUNDS 0,00% 20.905 SH 19 Agosto 2026 Giornaliero

LXRX Consenso degli analisti Opinioni degli analisti, sia rialziste che ribassiste, target price a 12 mesi, potenziale di rialzo

21
rating · 11 analisti COMPRA
Target mediano $4.55 +150,0%
3 27,3% Acquisto forte
5 45,5% Compra
3 27,3% Mantieni
0 0,0% Vendi
0 0,0% Vendita forte

Target Price a 12 Mesi

6 analisti · 2026-09-30

Target medio $4.55 +149,8%

← Sotto tutti i target Prezzo attuale $1.82
Basso$2.00 Media$4.55 Alto$8.00

Confronto Peer (GICS sub-settore industriale) Metriche chiave rispetto ai pari del settore

22

Base FY, prezzi alla chiusura dell'ultimo anno fiscale di ciascuna società.

Ticker Capitalizzazione di Mercato P/E Rev YoY Margine Netto ROE Margine lordo
LXRX $421M -8.2 60.2% -101.1% -39.7% ·
ANRO $568M -8.1 · · -46.1% ·
ALMS · -3.4 · -1011.8% -61.9% ·
APMD · · · · · ·
SGP · · · · 50.0% ·
COLL $1.47B 26.8 23.6% 8.1% 23.5% 59.4%
ACRS $363M -5.7 -58.2% -829.6% -55.3% ·
ZVRA $509M 6.6 350.9% 78.2% 61.2% ·
AQST $788M -8.3 -22.6% -188.1% 157.7% ·
PHAT $1.18B -5.5 216.9% -126.4% 52.4% 87.1%

Ultime notizie Notizie recenti che menzionano questa società

23

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26

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Fonte: SEC 10-Q depositato Ago 6, 2026